keyword
MENU ▼
Read by QxMD icon Read
search

Neuromuscular stimulation

keyword
https://www.readbyqxmd.com/read/28077717/complexin-mutants-reveal-partial-segregation-between-recycling-pathways-that-drive-evoked-and-spontaneous-neurotransmission
#1
Nadezhda Sabeva, Richard W Cho, Alexander Vasin, Agustin Gonzalez, J Troy Littleton, Maria Bykhovskaia
: Synaptic vesicles fuse at morphological specializations in the presynaptic terminal termed active zones (AZs). Vesicle fusion can occur spontaneously or in response to an action potential. Following fusion, vesicles are retrieved and recycled within nerve terminals. It is still unclear whether vesicles that fuse spontaneously or following evoked release share similar recycling mechanisms. Genetic deletion of the SNARE-binding protein complexin dramatically increases spontaneous fusion, with the protein serving as the synaptic vesicle fusion clamp at Drosophila synapses...
January 11, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28077312/the-effect-of-calf-neuromuscular-electrical-stimulation-and-intermittent-pneumatic-compression-on-thigh-microcirculation
#2
Shayan Bahadori, Tikki Immins, Thomas W Wainwright
OBJECTIVE: This study compares the effectiveness of a neuromuscular electrical stimulation (NMES) device and an intermittent pneumatic compression (IPC) device on enhancing microcirculatory blood flow in the thigh of healthy individuals, when stimulation is carried out peripherally at the calf. MATERIALS AND METHODS: Blood microcirculation of ten healthy individuals was recorded using laser speckle contrast imaging (LSCI) technique.A region of interest (ROI) was marked on each participant thigh...
January 8, 2017: Microvascular Research
https://www.readbyqxmd.com/read/28060035/etiology-and-recovery-of-neuromuscular-fatigue-following-simulated-soccer-match-play
#3
Kevin Thomas, Jack Dent, Glyn Howatson, Stuart Goodall
PURPOSE: We profiled the etiology and recovery of neuromuscular fatigue post-simulated-soccer-match-play. METHODS: Fifteen semi-professional players completed a 90 min simulated soccer match. Pre-, immediately-post and at 24, 48 and 72 h participants completed a battery of neuromuscular, physical and perceptual tests. Perceived fatigue and muscle soreness were assessed via visual analogue scales. Maximum voluntary contraction (MVC) and twitch responses to electrical (femoral nerve) and magnetic (motor cortex) stimulation during isometric knee-extensor contractions and at rest were measured to assess central (voluntary activation, VA) and peripheral (quadriceps potentiated twitch force, Qtw,pot) fatigue, and responses to single and paired-magnetic stimuli were assessed to quantify corticospinal excitability and short-intracortical inhibition (SICI), respectively...
January 3, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28051969/effects-of-adding-neuromuscular-electrical-stimulation-to-traditional-military-amputee-rehabilitation
#4
Laura A Talbot, Emily Brede, E Jeffrey Metter
BACKGROUND: Traumatic transtibial amputations lead to an early decline in the use and weight bearing of the residual limb. These changes result in progressive quadriceps muscle atrophy with strength loss that affects standing and walking. Neuromuscular electrical stimulation (NMES) may be useful as an adjunct to amputee prosthetic rehabilitation to maintain quadriceps muscle strength and mass. The objective of this pilot study was to compare the effects of a home-based NMES rehabilitation program plus the traditional military amputee rehabilitation program (TMARP) to the effects of TMARP alone on quadriceps muscle strength, functional mobility, and pain in military service members after a combat-related lower extremity amputation...
January 2017: Military Medicine
https://www.readbyqxmd.com/read/28045856/a-multiparametric-alarm-criterion-for-motor-evoked-potential-monitoring-during-spine-deformity-surgery
#5
Martín J Segura, María E Talarico, Mariano A Noel
PURPOSE: This is a pilot study to compare changes in the amplitude, area below the curve, number of phases, duration, and latency of the intraoperative transcranial motor evoked potentials (TcMEP) for early detection of impending spinal cord injury. An empirical ratio calculated by a combination of the above-mentioned parameters was also assessed. METHODS: Intraoperative TcMEP recordings from five patients presenting with neuromuscular kyphoscoliosis, idiopathic scoliosis, achondroplasia and lumbar kyphosis, congenital kyphosis, and achondroplasia with cervical instability were reviewed...
January 2017: Journal of Clinical Neurophysiology: Official Publication of the American Electroencephalographic Society
https://www.readbyqxmd.com/read/28042994/assessing-neuromuscular-junction-stability-from-stimulated-emg-in-children
#6
Matthew C Pitt, John C Mchugh, Jacquie Deeb, Ralph A Smith
OBJECTIVE: We present our 9-year experience of stimulated EMG potential analysis using concentric electrodes (SPACE) to evaluate neuromuscular junction (NMJ) disorders in awake children. The technique uses high frequency filtration of stimulated motor unit potentials and applies peak detection software to estimate mean consecutive difference (MCD). METHODS: SPACE was carried out in orbicularis oculi of 878 children (377 girls; median age 47months) between 2007 and 2015, stimulating the facial nerve with a monopolar cathode...
December 3, 2016: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28039397/physical-exercise-in-aging-human-skeletal-muscle-increases-mitochondrial-calcium-uniporter-expression-levels-and-affects-mitochondria-dynamics
#7
Sandra Zampieri, Cristina Mammucari, Vanina Romanello, Laura Barberi, Laura Pietrangelo, Aurora Fusella, Simone Mosole, Gaia Gherardi, Christian Höfer, Stefan Löfler, Nejc Sarabon, Jan Cvecka, Matthias Krenn, Ugo Carraro, Helmut Kern, Feliciano Protasi, Antonio Musarò, Marco Sandri, Rosario Rizzuto
Age-related sarcopenia is characterized by a progressive loss of muscle mass with decline in specific force, having dramatic consequences on mobility and quality of life in seniors. The etiology of sarcopenia is multifactorial and underlying mechanisms are currently not fully elucidated. Physical exercise is known to have beneficial effects on muscle trophism and force production. Alterations of mitochondrial Ca(2+) homeostasis regulated by mitochondrial calcium uniporter (MCU) have been recently shown to affect muscle trophism in vivo in mice...
December 2016: Physiological Reports
https://www.readbyqxmd.com/read/28032141/vestibular-control-of-standing-balance-is-enhanced-with-increased-cognitive-load
#8
Michael A McGeehan, Marjorie H Woollacott, Brian H Dalton
When cognitive load is elevated during a motor task, cortical inhibition and reaction time are increased; yet, standing balance control is often unchanged. This disconnect is likely explained by compensatory mechanisms within the balance system such as increased sensitivity of the vestibulomotor pathway. This study aimed to determine the effects of increased cognitive load on the vestibular control of standing balance. Participants stood blindfolded on a force plate with their head facing left and arms relaxed at their sides for two trials while exposed to continuous electrical vestibular stimulation (EVS)...
December 28, 2016: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/28031759/evaluation-of-the-effects-of-neuromuscular-electrical-stimulation-of-the-lower-limbs-combined-with-pulmonary-rehabilitation-on-exercise-tolerance-in-patients-with-chronic-obstructive-pulmonary-disease
#9
Cezary Kucio, Justyna Niesporek, Ewa Kucio, Dominika Narloch, Bartosz Węgrzyn
Chronic obstructive pulmonary disease (COPD) is a systemic disease with multiple extrapulmonary manifestations including impeded skeletal muscle function, leading to decreased muscular strength and endurance in patients with COPD. Pulmonary rehabilitation eases the symptoms of the condition and produces increased muscular endurance. Neuromuscular electrical stimulation (NMES) may serve as a treatment alternative to traditional pulmonary rehabilitation. The aim of the study was to assess the effects of NMES combined with pulmonary rehabilitation on exercise tolerance in patients in comparison with pulmonary rehabilitation alone...
December 1, 2016: Journal of Human Kinetics
https://www.readbyqxmd.com/read/28027644/label-free-imaging-of-neurotransmitter-acetylcholine-at-neuromuscular-junctions-with-stimulated-raman-scattering
#10
Dan Fu, Wenlong Yang, Xiaoliang Sunney Xie
Acetylcholine is an important neurotransmitter that relays neural excitation from lower motor neurons to muscles. It also plays significant roles in the central nervous system by modulating neurotransmission. However, there is a lack of tools to directly measure the quantity and distribution of acetylcholine at the subcellular level. In this Communication, we demonstrate for the first time that label-free imaging of acetylcholine is achieved with frequency-modulated spectral-focusing stimulated Raman scattering (FMSF-SRS) microscopy: a technical improvement over traditional SRS microscopy that effectively removes imaging backgrounds...
December 30, 2016: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28008303/regenerated-sciatic-nerve-axons-stimulated-through-a-chronically-implanted-macro-sieve-electrode
#11
Matthew R MacEwan, Erik R Zellmer, Jesse J Wheeler, Harold Burton, Daniel W Moran
Sieve electrodes provide a chronic interface for stimulating peripheral nerve axons. Yet, successful utilization requires robust axonal regeneration through the implanted electrode. The present study determined the effect of large transit zones in enhancing axonal regeneration and revealed an intimate neural interface with an implanted sieve electrode. Fabrication of the polyimide sieve electrodes employed sacrificial photolithography. The manufactured macro-sieve electrode (MSE) contained nine large transit zones with areas of ~0...
2016: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28006886/neuromuscular-effect-of-dexmedetomidine-on-sevoflurane-an-open-label-dose-escalation-clinical-trial
#12
Hui H Ke, Huang H Wu, Qi Zhu, Yan Zhang, Jin R Xiao, Xiu Z Su, Wan J Zheng, Yu P Cai, Xiao Z Wu, Yu T Wang, Guo Z Chen
BACKGROUND: Sevoflurane presents reliable central neuromuscular effects. However, little knowledge is available regarding the interaction between sevoflurane and demedetomidine. We evaluated the neuromuscular effect of dexmedetomidine on sevoflurane in patients with normal neuromuscular transmission and calculated the 50% effective concentration (EC50). METHODS: One-hundred and forty-four ASA grade I~II patients with normal neuromuscular transmission, aged 20~60 years old, undergoing lower limbs surgery were enrolled in this open- label, dose-escalation clinical trial...
December 22, 2016: Minerva Anestesiologica
https://www.readbyqxmd.com/read/28002179/game-profile-based-training-in-soccer-a-new-field-approach
#13
Antonio Dello Iacono, Domenico Martone, Drazen Cular, Mirjana Milic, Johnny Padulo
The aim of the study was to profile and compare the time-motion, physiological, and neuromuscular responses of both national youth league (NYL) and UEFA Youth League (UYL) matches with those of an experimental game-profile-based training (GPBT) protocol. Time-motion traits and physiological, perceptual, and neuromuscular responses were investigated in 24 male soccer players across 14 matches and 6 GPBT training sessions, for a total of 420 samples. The GPBT had a greater influence on time-motion traits and perceptual responses than the NYL and UYL matches (all p< 0...
December 8, 2016: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/27998908/loss-of-laminin-%C3%AE-4-results-in-pre-and-postsynaptic-modifications-at-the-neuromuscular-junction
#14
Kirat K Chand, Kah Meng Lee, Nickolas A Lavidis, Peter G Noakes
Synaptic basal lamina such as laminin-421 (α4β2γ1) mediate differentiation of the neuromuscular junction (NMJ). Laminins interact with their pre- or postsynaptic receptors to provide stability and alignment of the pre- to postsynaptic specializations. Knockout of the lama4 gene does not alter gross NMJ morphogenesis. However, mice deficient in laminin-α4 (lama4(-/-)) display disruptions in the alignment of the active zones and postsynaptic folds at the NMJ, although the physiological consequences of this loss have not been examined...
December 20, 2016: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/27990239/towards-parameters-and-protocols-to-recommend-fes-cycling-in-cases-of-paraplegia-a-preliminary-report
#15
Juliana Araujo Guimarães, Lucas Oliveira da Fonseca, Clarissa Cardoso Dos Santos-Couto-Paz, Antônio Padilha Lanari Bó, Charles Fattal, Christine Azevedo-Coste, Emerson Fachin-Martins
Functional Electrical Stimulation assisted cycling (FES-Cycling) is increasingly becoming an alternative option recommended to people with spinal cord injury struggling with paraplegia and interested in practicing sports. In order to propose preconditions to guide FES-Cycling recommendation, we aimed to investigate some features and their potential relationships with responsiveness to Neuromuscular Electrical Stimulation (NMES). Fourteen volunteers attended a public recruitment forum to be assessed about their responsiveness through the 16-sessions of NMES...
June 13, 2016: European Journal of Translational Myology
https://www.readbyqxmd.com/read/27990107/a-novel-striated-muscle-specific-myosin-blocking-drug-for-the-study-of-neuromuscular-physiology
#16
Dante J Heredia, Douglas Schubert, Siddhardha Maligireddy, Grant W Hennig, Thomas W Gould
The failure to transmit neural action potentials (APs) into muscle APs is referred to as neuromuscular transmission failure (NTF). Although synaptic dysfunction occurs in a variety of neuromuscular diseases and impaired neurotransmission contributes to muscle fatigue, direct evaluation of neurotransmission by measurement of successfully transduced muscle APs is difficult due to the subsequent movements produced by muscle. Moreover, the voltage-gated sodium channel inhibitor used to study neurotransmitter release at the adult neuromuscular junction is ineffective in embryonic tissue, making it nearly impossible to precisely measure any aspect of neurotransmission in embryonic lethal mouse mutants...
2016: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/27981910/multilevel-analysis-of-locomotion-in-immature-preparations-suggests-innovative-strategies-to-reactivate-stepping-after-spinal-cord-injury
#17
Michele R Brumley, Pierre A Guertin, Giuliano Taccola
Locomotion is one of the most complex motor behaviors. Locomotor patterns change during early life, reflecting development of numerous peripheral and hierarchically organized central structures. Among them, the spinal cord is of particular interest since it houses the central pattern generator (CPG) for locomotion. This main command center is capable of eliciting and coordinating complex series of rhythmic neural signals sent to motoneurons and to corresponding target-muscles for basic locomotor activity. For a long-time, the CPG has been considered a black box...
December 14, 2016: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/27981782/neuromuscular-changes-and-the-rapid-adaptation-following-a-bout-of-damaging-eccentric-exercise
#18
Stuart Goodall, Kevin Thomas, Martin Barwood, Karen Keane, Javier T Gonzalez, Alan St Clair Gibson, Glyn Howatson
To determine if neuromuscular disturbances are modulated following a repeated bout of eccentric exercise METHODS: Following eccentric exercise performed with the elbow-flexors, we measured maximal voluntary force, resting twitch force, muscle soreness, creatine kinase and voluntary activation using motor point and motor cortex stimulation at baseline, immediately post and at 1, 2, 3, 4 and 7 days post-exercise on two occasions, separated by 3 weeks RESULTS: Significant muscle damage and fatigue was evident following the first exercise bout; maximal voluntary contraction was reduced immediately by 32% and remained depressed at 7 days post-exercise...
December 16, 2016: Acta Physiologica
https://www.readbyqxmd.com/read/27935072/physical-exercise-in-myasthenia-gravis-is-safe-and-improves-neuromuscular-parameters-and-physical-performance-based-measures-a-pilot-study
#19
Elisabet Westerberg, Carl Johan Molin, Ida Lindblad, Margareta Emtner, Anna Rostedt Punga
INTRODUCTION: Due to the shortage of exercise-related research in Myasthenia Gravis (MG), there are no consensus guidelines on physical exercise for MG patients. METHODS: In this prospective pilot study, 10 MG patients with mild disease performed supervised aerobic and resistance training twice weekly for 12 weeks. The Myasthenia Gravis Composite (MGC) score, compound motor action potential (CMAP), repetitive nerve stimulation, muscle force, physical performance-based measures, serum levels of interleukin-6, muscle enzymes as well as immuno-microRNAs miR-150-5p and miR-21-5p were assessed before and after the training period...
December 9, 2016: Muscle & Nerve
https://www.readbyqxmd.com/read/27935068/single-fiber-emg-with-concentric-electrodes-in-lambert-eaton-myasthenia
#20
Yuzhou Guan, Qingyun Ding, Mingsheng Liu, Jingwen Niu, Liying Cui
INTRODUCTION: We analyzed jitter recordings made with concentric needle electrode single-fiber EMG (CNE-SFEMG) in Lambert-Eaton myasthenia (LEM). METHODS: Fifteen subjects diagnosed with LEM were studied using CNE-SFEMG in the extensor digitorum (ED) and tibialis anterior (TA) muscles. CNE-SFEMG in the ED and TA was also used to evaluate 12 and 10 healthy controls (HCs), respectively. RESULTS: Ten men and 5 women were diagnosed with LEM based on an increase of 100% in compound muscle action potential (CMAP) amplitude during 50 Hz repetitive nerve stimulation...
December 9, 2016: Muscle & Nerve
keyword
keyword
74507
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"