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Neuromuscular stimulation

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https://www.readbyqxmd.com/read/27919609/randomised-controlled-trial-potential-benefit-of-a-footplate-neuromuscular-electrical-stimulation-device-in-patients-with-chronic-venous-disease
#1
R Ravikumar, K J Williams, A Babber, T R A Lane, H M Moore, A H Davies
OBJECTIVES: Chronic venous disease (CVD) is common, affecting a quarter of the population. Current conservative methods of treatment aim to prevent progression of disease by reducing ambulatory venous pressure. Neuromuscular electrical stimulation (NMES) refers to the use of electrical impulses to elicit muscle contraction. This pilot randomised controlled trial investigates the effect of a footplate NMES device (REVITIVE) on venous flow parameters, limb oedema, and quality of life outcome measures in patients with CVD...
December 2, 2016: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/27913592/complexin-mutants-reveal-partial-segregation-between-recycling-pathways-that-drive-evoked-and-spontaneous-neurotransmission
#2
Nadezhda Sabeva, Richard W Cho, Alexander Vasin, Agustin Gonzalez, J Troy Littleton, Maria Bykhovskaia
: Synaptic vesicles fuse at morphological specializations in the presynaptic terminal termed active zones (AZs). Vesicle fusion can occur spontaneously or in response to an action potential. Following fusion, vesicles are retrieved and recycled within nerve terminals. It is still unclear whether vesicles that fuse spontaneously or following evoked release share similar recycling mechanisms. Genetic deletion of the SNARE-binding protein complexin dramatically increases spontaneous fusion, with the protein serving as the synaptic vesicle fusion clamp at Drosophila synapses...
December 2, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/27899898/effects-of-neuromuscular-electrical-stimulation-training-on-endurance-performance
#3
Menno P Veldman, Julien Gondin, Nicolas Place, Nicola A Maffiuletti
No abstract text is available yet for this article.
2016: Frontiers in Physiology
https://www.readbyqxmd.com/read/27882697/biomechanical-properties-of-an-implanted-engineered-tubular-gut-sphincter-complex
#4
Elie Zakhem, Mostafa El Bahrawy, Giuseppe Orlando, Khalil N Bitar
Neuromuscular diseases of the gut alter the normal motility patterns. Although surgical intervention remains the standard treatment, preservation of the sphincter attached to the rest of the gut is challenging. The present study aimed to evaluate a bioengineered gut-sphincter complex following its subcutaneous implantation for 4 weeks in rats. Engineered innervated human smooth muscle sheets and innervated human sphincters with a predefined alignment were placed around tubular scaffolds to create a gut-sphincter complex...
November 23, 2016: Journal of Tissue Engineering and Regenerative Medicine
https://www.readbyqxmd.com/read/27881401/alterations-of-colonic-function-in-the-winnie-mouse-model-of-spontaneous-chronic-colitis
#5
Ainsley M Robinson, Ahmed A Rahman, Simona Elisa Carbone, Sarron Randall-Demllo, Rhiannon Filippone, Joel Charles Bornstein, Rajaraman Eri, Kulmira Nurgali
The Winnie mouse, carrying a missense mutation in Muc2, is a model for chronic intestinal inflammation demonstrating symptoms closely resembling inflammatory bowel disease (IBD). Alterations to the immune environment, morphological structure and innervation of Winnie mouse colon have been identified; however analyses of intestinal transit and colonic functions have not been conducted. In this study, we investigated in vivo intestinal transit in radiographic studies and in vitro motility of the isolated colon in organ bath experiments...
November 23, 2016: American Journal of Physiology. Gastrointestinal and Liver Physiology
https://www.readbyqxmd.com/read/27863913/commentary-on-randomised-controlled-trial-potential-benefit-of-a-footplate-neuromuscular-electrical-stimulation-device-in-patients-with-chronic-venous-disease
#6
S K Kakkos, I A Tsolakis
No abstract text is available yet for this article.
November 15, 2016: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/27862051/comparison-of-the-ballistic-contractile-responses-generated-during-microstimulation-of-single-human-motor-axons-with-brief-irregular-and-regular-stimuli
#7
Michael Leitch, Vaughan G Macefield
INTRODUCTION: Ballistic contractions are induced by brief, high frequency (60-100 Hz) trains of action potentials in motor axons. During ramp voluntary contractions, human motoneurones exhibit significant discharge variability of ∼20% and have shown to be advantageous to the neuromuscular system. We hypothesized that ballistic contractions incorporating discharge variability generate greater isometric forces than regular trains with zero variability. METHODS: High impedance tungsten microelectrodes were inserted into the fibular nerve, and single motor axons were stimulated with both irregular and constant-frequency stimuli at mean frequencies ranging from 57...
November 11, 2016: Muscle & Nerve
https://www.readbyqxmd.com/read/27862023/fatigue-reduction-during-aggregated-and-distributed-sequential-stimulation
#8
Austin J Bergquist, Vishvek Babbar, Saima Ali, Milos R Popovic, Masani Kei
INTRODUCTION: Transcutaneous neuromuscular electrical stimulation (NMES) can generate muscle contractions for rehabilitation and exercise. However, NMES-evoked contractions are limited by fatigue when they are delivered "conventionally" (CONV) using a single active electrode. Researchers developed "sequential" (SEQ) stimulation, involving rotation of pulses between multiple "aggregated" (AGGR-SEQ) or "distributed" (DISTR-SEQ) active electrodes, to reduce fatigue (torque-decline) by reducing motor unit discharge rates...
November 11, 2016: Muscle & Nerve
https://www.readbyqxmd.com/read/27859286/effects-of-electrical-stimulation-on-vocal-functions-in-patients-with-nasopharyngeal-carcinoma
#9
Thomas Law, Kathy Y-S Lee, Rita W-M Wong, Yeptain Leung, Peter K-M Ku, Eddy W-Y Wong, Hok-Nam Li, Louisa K-Y Ng, C Andrew van Hasselt, Michael C-F Tong
OBJECTIVES/HYPOTHESIS: This study aimed to evaluate the effects of neuromuscular electrical stimulation (NMES) on vocal functions in patients with nasopharyngeal carcinoma following radiation therapy. STUDY DESIGN: Prospective, randomized controlled trial. METHODS: One hundred forty newly treated NPC patients were recruited and randomized into NMES or traditional swallowing exercise (TE) group. Participants received intensive NMES or traditional swallowing therapy and were followed up until 12 months postrandomization...
November 12, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27852784/activity-induces-fmr1-sensitive-synaptic-capture-of-anterograde-circulating-neuropeptide-vesicles
#10
Samantha L Cavolo, Dinara Bulgari, David L Deitcher, Edwin S Levitan
: Synaptic neuropeptide and neurotrophin stores are maintained by constitutive bidirectional capture of dense-core vesicles (DCVs) as they circulate in and out of the nerve terminal. Activity increases DCV capture to rapidly replenish synaptic neuropeptide stores following release. However, it is not known whether this is due to enhanced bidirectional capture. Here experiments at the Drosophila neuromuscular junction, where DCVs contain neuropeptides and a bone morphogenic protein, show that activity-dependent replenishment of synaptic neuropeptides following release is evident after inhibiting the retrograde transport with the dynactin disruptor mycalolide B or photobleaching DCVs entering a synaptic bouton by retrograde transport...
November 16, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/27850101/461-neuromuscular-electrical-stimulation-may-exert-a-therapeutic-effect-for-acute-endotoxic-shock-mice
#11
Takayuki Irahara, Norio Sato, Kosuke Otake, Shigenobu Matsumura, Kazuo Inoue, Kaoru Koike, Hiroyuki Yokota
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27845664/the-time-varying-nature-of-electromechanical-delay-and-muscle-control-effectiveness-in-response-to-stimulation-induced-fatigue
#12
Ryan J Downey, Manelle Merad, Eric J Gonzalez, Warren E Dixon
Neuromuscular Electrical Stimulation (NMES) and Functional Electrical Stimulation (FES) are commonly prescribed rehabilitative therapies. Closed-loop NMES holds the promise to yield more accurate limb control, which could enable new rehabilitative procedures. However, NMES/FES can rapidly fatigue muscle, which limits potential treatments and presents several control challenges. Specifically, the stimulation intensity-force relation changes as the muscle fatigues. Additionally, the delayed response between the application of stimulation and muscle force production, termed electromechanical delay (EMD), may increase with fatigue...
November 8, 2016: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/27845663/demonstration-of-2-mm-thick-microcontrolled-injectable-stimulators-based-on-rectification-of-high-frequency-current-bursts
#13
Laura Becerra Fajardo, Marieluise Schmidbauer, Antoni Ivorra
Existing implantable stimulators use powering approaches that result in stiff and bulky systems or result in systems incapable of producing the current magnitudes required for neuromuscular stimulation. This hampers their use in neuroprostheses for paralysis. We previously demonstrated an electrical stimulation method based on electronic rectification of high frequency (HF) current bursts. The implants act as rectifiers of HF current that flows through the tissues by galvanic coupling, transforming this current into low frequency current capable of performing neuromuscular stimulation...
October 31, 2016: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/27834612/the-effectiveness-of-neuromuscular-electrical-stimulation-in-improving-voluntary-activation-of-the-quadriceps-a-critically-appraised-topic
#14
Cody B Bremner, William R Holcomb, Christopher D Brown, Melanie E Perreault
: Clinical Scenario: Orthopedic knee conditions are regularly treated in sports medicine clinics. Rehabilitation protocols for these conditions are often designed to address the associated quadriceps strength deficits. Despite these efforts, patients with orthopedic knee conditions often fail to completely regain their quadriceps strength. Disinhibitory modalities have recently been suggested as a clinical tool that can be used to counteract the negative effects of arthrogenic muscle inhibition (AMI), which is believed to limit the effectiveness of therapeutic exercise...
November 11, 2016: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/27832594/high-frequency-neuromuscular-electrical-stimulation-modulates-interhemispheric-inhibition-in-healthy-humans
#15
Nicolas Gueugneau, Sidney Grosprêtre, Paul J Stapley, Romuald Lepers
High frequency neuromuscular electrical stimulation (HF NMES) induces muscular contractions through neural mechanisms that partially match physiological motor control. Indeed, a portion of the contraction arises from central mechanisms, whereby spinal motoneurons are recruited through the evoked sensory volley. However, the involvement of supraspinal centers of motor control during such a stimulation remained poorly understood. Therefore, we tested whether a single HF NMES session applied to the upper limb influences interhemispheric inhibition (IHI) from left to right motor cortex (M1)...
November 9, 2016: Journal of Neurophysiology
https://www.readbyqxmd.com/read/27831886/demonstration-of-2-mm-thick-microcontrolled-injectable-stimulators-based-on-rectification-of-high-frequency-current-bursts
#16
Laura Becerra-Fajardo, Marieluise Schmidbauer, Antoni Ivorra
Existing implantable stimulators use powering approaches that result in stiff and bulky systems or result in systems incapable of producing the current magnitudes required for neuromuscular stimulation. This hampers their use in neuroprostheses for paralysis. We previously demonstrated an electrical stimulation method based on electronic rectification of high frequency (HF) current bursts. The implants act as rectifiers of HF current that flows through the tissues by galvanic coupling, transforming this current into low frequency current capable of performing neuromuscular stimulation...
October 31, 2016: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/27829262/-upper-airway-stimulation-in-osa
#17
B Bender
Anatomical basis of obstructive sleep apnea (OSA) is the collapse of the pharynx during sleep. It is considered as a result of complex interactions of structural and neuromuscular factors. Depth of sleep and body position have modulating effects. Although different areas of obstruction were identified, studies show that the sleep-mediated obstruction frequently occurs in the base of tongue area.Continuous positive airway pressure (CPAP) is the standard treatment for obstructive sleep apnea syndrome (OSAS) since more than 30 years...
November 2016: Laryngo- Rhino- Otologie
https://www.readbyqxmd.com/read/27828786/the-effect-of-prior-tetanic-stimulation-on-train-of-four-monitoring-in-paediatric-patients-a-randomised-open-label-controlled-trial
#18
Ricardo V Carlos, Hans Donald de Boer, Marcelo Luis Abramides Torres, Maria José Carvalho Carmona
BACKGROUND: In clinical research, neuromuscular monitoring must present a stable response for a period of 2 to 5 min before administration of a neuromuscular blocking agent. The time required to reach this stable response may be shortened by applying a 5-s tetanic stimulus. OBJECTIVES: The aim of this study was to test whether tetanic stimulation interferes with onset and recovery times after a single dose of rocuronium 0.6 mg kg followed by spontaneous recovery...
November 8, 2016: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/27826108/knee-extensors-neuromuscular-fatigue-changes-the-corticospinal-pathway-excitability-in-biceps-brachii-muscle
#19
Saied Jalal Aboodarda, Nemanja Šambaher, Guillaume Y Millet, David G Behm
Equivocal evidence indicates that high-intensity muscle contractions can affect the corticospinal responses in muscles not directly involved in the task. In the present study, the responsiveness of corticomotor pathway innervating non-dominant biceps brachii was measured in eleven healthy participants before and after: (i) two 100-s isometric unilateral knee extension maximal voluntary contractions (MVCs) on dominant leg (FATIGUE) and (ii) rest (CONTROL). Transcranial magnetic stimulation, transmastoid electrical and brachial plexus electrical stimulation were used to evoke motor evoked potential (MEP), cervicomedullary motor evoked potential (CMEP) and compound muscle action potential (Mmax) in biceps brachii muscle...
November 5, 2016: Neuroscience
https://www.readbyqxmd.com/read/27825837/effects-of-functional-electrical-stimulation-on-reducing-falls-and-improving-gait-parameters-in-multiple-sclerosis-and-stroke
#20
Elisa Gervasoni, Riccardo Parelli, Marcin Uszynski, Alessandro Crippa, Alberto Marzegan, Angelo Montesano, Davide Cattaneo
BACKGROUND: Loss of neuromuscular control of the ankle joint is a common impairment in neurologic conditions, leading to abnormal gait and a greater risk of falling. Limited information, however, is available on the effectiveness of functional electrical stimulation (FES) on reducing falls, and no studies have investigated its usefulness in improving lower limbs kinematics related to foot clearance and energy recovery. SETTING: Clinical setting. STUDY DESIGN: Prospective longitudinal study...
November 4, 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
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