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Kallol K Roy, Sandeep Metta, Yamini Kansal, Sunesh Kumar, Seema Singhal, Perumal Vanamail
Study Objective: To compare the operative and reproductive outcome of hysteroscopic myomectomy using unipolar resectoscope versus bipolar resectoscope in patients with infertility and menorrhagia. Design: Randomized, prospective, parallel, comparative, single-blinded study. Design Classification: Canadian Task Force classification I. Setting: Tertiary care institute. Patients: Sixty women with submucous myoma and infertility...
July 2017: Journal of Human Reproductive Sciences
Eva Wiese, Giorgio Metta, Agnieszka Wykowska
Robots are increasingly envisaged as our future cohabitants. However, while considerable progress has been made in recent years in terms of their technological realization, the ability of robots to interact with humans in an intuitive and social way is still quite limited. An important challenge for social robotics is to determine how to design robots that can perceive the user's needs, feelings, and intentions, and adapt to users over a broad range of cognitive abilities. It is conceivable that if robots were able to adequately demonstrate these skills, humans would eventually accept them as social companions...
2017: Frontiers in Psychology
Wenting Cai, Roser Morales-Martínez, Xingxing Zhang, Daniel Najera, Elkin L Romero, Alejandro Metta-Magaña, Antonio Rodríguez-Fortea, Skye Fortier, Ning Chen, Josep M Poblet, Luis Echegoyen
Charge transfer is a general phenomenon observed for all endohedral mono-metallofullerenes. Since the detection of the first endohedral metallofullerene (EMF), La@C82, in 1991, it has always been observed that the oxidation state of a given encapsulated metal is always the same, regardless of the cage size. No crystallographic data exist for any early actinide endohedrals and little is known about the oxidation states for the few compounds that have been reported. Here we report the X-ray structures of three uranium metallofullerenes, U@D3h-C74, U@C2(5)-C82 and U@C2v(9)-C82, and provide theoretical evidence for cage isomer dependent charge transfer states for U...
August 1, 2017: Chemical Science
Jenna E Boyd, Ruth A Lanius, Margaret C McKinnon
Mindfulness-based treatments for posttraumatic stress disorder (PTSD) have emerged as promising adjunctive or alternative intervention approaches. A scoping review of the literature on PTSD treatment studies, including approaches such as mindfulness-based stress reduction, mindfulness-based cognitive therapy and metta mindfulness, reveals low attrition with medium to large effect sizes. We review the convergence between neurobiological models of PTSD and neuroimaging findings in the mindfulness literature, where mindfulness interventions may target emotional under- and overmodulation, both of which are critical features of PTSD symptomatology...
October 2, 2017: Journal of Psychiatry & Neuroscience: JPN
Arnab K Maity, Jesse Murillo, Alejandro J Metta-Magaña, Balazs Pinter, Skye Fortier
Utilizing the bulky guanidinate ligand [L(Ar*)](-) (L(Ar*) = (Ar*N)2C(R), Ar* = 2,6-bis(diphenylmethyl)-4-tert-butylphenyl, R = NC(t)Bu2) for kinetic stabilization, the synthesis of a rare terminal Fe(IV) nitride complex is reported. UV irradiation of a pyridine solution of the Fe(II) azide [L(Ar*)]FeN3(py) (3-py) at 0 °C cleanly generates the Fe(IV) nitride [L(Ar*)]FeN(py) (1). The (15)N NMR spectrum of the 1((15)N) (50% Fe≡(15)N) isotopomer shows a resonance at 1016 ppm (vs externally referenced CH3NO2 at 380 ppm), comparable to that known for other terminal iron nitrides...
October 19, 2017: Journal of the American Chemical Society
Metta Riebesell, Ralf J Sommer
Pristionchus pacificus is a model system in evolutionary biology and for comparison to Caenorhabditis elegans. As a necromenic nematode often found in association with scarab beetles, P. pacificus exhibits omnivorous feeding that is characterized by a mouth-form dimorphism, an example of phenotypic plasticity. Eurystomatous animals have a dorsal and a sub-ventral tooth enabling predatory feeding on other nematodes whereas stenostomatous animals have only a dorsal tooth and are microbivorous. Both mouth forms of P...
September 12, 2017: Journal of Morphology
Giuseppe D Ciccotosto, Metta Jana, Roberto Cappai
Prion neurotoxicity has been modeled in vitro using synthetic peptides derived from the PrP(C) sequence. The major region of neurotoxicity has been localized to the hydrophobic domain located in the middle of the PrP protein. Neurotoxicity assays are typically performed on cultured mouse cerebellar neurons derived from neonatal pups, and cell viability can be monitored by assays including MTT or MTS, cell death by LDH release, or apoptosis by caspase cleavage assays. These neurotoxicity studies have been useful in identifying cofactors, such as PrP(C) and metals, as modulators of PrP peptide-mediated neurotoxicity...
2017: Methods in Molecular Biology
Vinod Metta, Tamara C Sanchez, Chandrasekhara Padmakumar
Osteoporosis is a "hidden nonmotor face" of Parkinson's disease and a cause of considerable morbidity in the older general population and in Parkinson's disease patients. Some regard this as a "hidden epidemic." Women are overrepresented and have considerable problems related to osteoporosis. In general osteoporosis leads to reduced mobility aggravating the motor syndrome of PD. The nonmotor aspects and impact of osteoporosis in PD have remained unexplored. Possible nonmotor consequences include a range of pain syndromes related to local pain, fractures, falls, and injuries as well as pathological fractures and radiculopathy...
2017: International Review of Neurobiology
Edison Castro, Khalid Azmani, Andrea Hernandez Garcia, Amineh Aghabali, Shuming Liu, Alejandro Metta-Magana, Marilyn Olmstead, Antonio Rodriguez-Fortea, Josep Poblet, Luis Echegoyen
A totally unanticipated regio- and stereo-isomerically pure C₂h-symmetric trans-1-(bis-pyrrolidine)-tetra-malonate hexa-adduct of C₆₀ was obtained via a topologically controlled method, followed by a 1,3-dipolar cycloaddition reaction. The structures of the products were elucidated by ¹H- and ¹³C-NMR and by X-ray crystallography. The unexpected regio- and stereo-selectivity observed, supported by theoretical calculations, was found to be a consequence of malonate-pyrrolidine interactions.
August 4, 2017: Chemistry: a European Journal
M Soma Sekhar, T Srinivasa Rao, B K Chinnam, K V Subramanyam, M Metta, N Mohammad Sharif
Arcobacter is an emerging foodborne pathogen having zoonotic significance. Enterobacterial repetitive intergenic consensus (ERIC) PCR and repetitive sequence-based PCR (rep-PCR) analysis of a total of 41 Arcobacter isolates revealed a greater degree of genetic diversity. ERIC-PCR genotyping distinguished 14, 13 and 12 genotypes among 16, 13 and 12 isolates of A. butzleri, A. cryaerophilus and A. skirrowii, respectively. Rep-PCR genotyping distinguished 15, 12 and 11 genotypes among 16, 13 and 12 isolates of A...
June 2017: Indian Journal of Microbiology
Emmy Metta, Ajay Bailey, Flora Kessy, Eveline Geubbels, Hinke Haisma
BACKGROUND: Tanzania is doubly burdened with both non-communicable and infectious diseases, but information on how Tanzanians experience the co-existence of these conditions is limited. Using Kleinman's eight prompting questions the study synthesizes explanatory models from patients to describe common illness experiences of diabetes in a rural setting where malaria is the predominant health threat. METHODS: We conducted 17 focus group discussions with adult members of the general community, diabetes patients, neighbours and relatives of diabetes patients to gain insight into shared experiences...
2017: PloS One
Nanda Kishore Panigrahi, Jagannadh Raju, Dibya Kumar Baruah, Metta Srinivas, Ravi Kumar Varma
No abstract text is available yet for this article.
April 24, 2017: JACC. Cardiovascular Interventions
Manoj Kumar Metta, Vasavi Malkhed, Srinivasan Tantravahi, Uma Vuruputuri, Rajkumar Kunaparaju
Determination of biological activity and its comparison with clinical behavior is important in the quality assessment of therapeutic glycoproteins. In vivo studies are usually employed for evaluating bioactivity of these glycomolecules. However, alternative methods are required to simplify the bioassay and avoid ethical issues associated with in vivo studies. Negatively charged sialic acid residues are known to be critical for in vivo bioactivity of rHuEPO. To address this need, we employed the human acute myeloid leukemia cell line UT-7 for the determination of proliferative stimulation induced by rHuEPO...
April 2017: Protein Journal
Duer Bolotaulo, Alejandro Metta-Magaña, Skye Fortier
Using an improved, chromatography-free dipyrrin synthesis, the α,β-unsubstituted dipyrrins [RC(C4H2N)2H] (2) (R = tolyl (2toly(l)), p-OMe-C6H4 (2anis), mesityl (2mes), ferrocenyl (2Fc)) were isolated in good to excellent yields. Deprotonation of 2 with Na[N(SiMe3)2] gives the alkali metal salts [Na(DME)n][RC(C4H2N)2] (3) which reacts with UO2Cl2(THF)3 to give the uranyl bis(dipyrrinates) UO2[RC(C4H2N)2]2(L) (L = THF (4R-THF); DMAP (4R-DMAP)) (R = tolyl, p-OMe-C6H4, mesityl, ferrocenyl). The THF adducts, 4R-THF, are unstable in aromatic and nonpolar solvents and rapidly decompose to 2 and an intractable uranium-containing solid...
February 22, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
Usha Singh, Attachai Ueranantasun, Metta Kuning
BACKGROUND: Survey data from low income countries on birth weight usually pose a persistent problem. The studies conducted on birth weight have acknowledged missing data on birth weight, but they are not included in the analysis. Furthermore, other missing data presented on determinants of birth weight are not addressed. Thus, this study tries to identify determinants that are associated with low birth weight (LBW) using multiple imputation to handle missing data on birth weight and its determinants...
February 20, 2017: BMC Pregnancy and Childbirth
Ramesh V V S Metta, Awais Zaka, Vincent C Lee, M Jeffery Mador
Purpose To determine the short-term and long-term adherence rates with continuous positive airway pressure (CPAP) therapy in sleep apnea patients with benign prostatic hyperplasia (BPH) compared to matched controls. Methods A case-control retrospective analysis was performed in a veterans affairs hospital. All symptomatic patients with BPH (n = 107) ever started on CPAP therapy between 2006 and 2012 were compared with controls matched for severity of sleep apnea (AHI). Adherence measures were obtained at the third and twelfth month visits...
April 2017: Lung
Tanut Pettong, Pawin Iamprasertkun, Atiweena Krittayavathananon, Phansiri Sukha, Pichamon Sirisinudomkit, Anusorn Seubsai, Metta Chareonpanich, Paisan Kongkachuichay, Jumras Limtrakul, Montree Sawangphruk
The working potential of symmetric supercapacitors is not so wide because one type of material used for the supercapacitor electrodes prefers either positive or negative charge to both charges. To address this problem, a novel asymmetrical supercapacitor (ASC) of battery-type MnCo2O4 nanofibers (NFs)//N-doped reduced graphene oxide aerogel (N-rGOAE) was fabricated in this work. The MnCo2O4 NFs at the positive electrode store the negative charges, i.e., solvated OH(-), while the N-rGOAE at the negative electrode stores the positive charges, i...
December 14, 2016: ACS Applied Materials & Interfaces
Maren C Podszun, Metta Jakobi, Marc Birringer, Johanna Weiss, Jan Frank
SCOPE: Members of the vitamin E family or their metabolites may induce the xenobiotic transporter P-glycoprotein (P-gp), which can limit the bioavailability of drugs and phytochemicals. This study aimed to investigate if α- and γ-tocopherol, α- and γ-tocotrienol, the long chain metabolite α-tocopherol-13'-COOH, the short chain metabolites α- and γ-carboxyethylhydroxychromanol and plastochromanol-8 activate the pregnane X receptor (PXR) and thereby modulate P-gp expression and/or activity...
October 6, 2016: Molecular Nutrition & Food Research
Alessandro Roncone, Matej Hoffmann, Ugo Pattacini, Luciano Fadiga, Giorgio Metta
This paper investigates a biologically motivated model of peripersonal space through its implementation on a humanoid robot. Guided by the present understanding of the neurophysiology of the fronto-parietal system, we developed a computational model inspired by the receptive fields of polymodal neurons identified, for example, in brain areas F4 and VIP. The experiments on the iCub humanoid robot show that the peripersonal space representation i) can be learned efficiently and in real-time via a simple interaction with the robot, ii) can lead to the generation of behaviors like avoidance and reaching, and iii) can contribute to the understanding the biological principle of motor equivalence...
2016: PloS One
Metta Dülk, Gyöngyi Kudlik, Anna Fekete, Dávid Ernszt, Krisztián Kvell, Judit E Pongrácz, Balázs L Merő, Bálint Szeder, László Radnai, Miklós Geiszt, Dalma E Csécsy, Tamás Kovács, Ferenc Uher, Árpád Lányi, Virag Vas, László Buday
The commitment steps of mesenchymal stromal cells (MSCs) to adipogenic and other lineages have been widely studied but not fully understood. Therefore, it is critical to understand which molecules contribute to the conversion of stem cells into differentiated cells. The scaffold protein Tks4 plays a role in podosome formation, EGFR signaling and ROS production. Dysfunction of Tks4 causes a hereditary disease called Frank-ter Haar syndrome with a variety of defects concerning certain mesenchymal tissues (bone, fat and cartilage) throughout embryogenic and postnatal development...
October 6, 2016: Scientific Reports
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