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https://www.readbyqxmd.com/read/29777664/this-month-in-ajp
#1
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The following highlights summarize research articles that are published in the current issue of The American Journal of Pathology.
May 16, 2018: American Journal of Pathology
https://www.readbyqxmd.com/read/29771193/early-symptoms-of-systemic-lupus-erythematosus-sle-recalled-by-339-sle-patients
#2
N Leuchten, B Milke, B Winkler-Rohlfing, D Daikh, T Dörner, S R Johnson, M Aringer
Objective The European League Against Rheumatism and the American College of Rheumatology jointly embarked on a new classification criteria for systemic lupus erythematosus (SLE) project. Its first phase involved generation of a broad set of items potentially useful for classification of SLE. This study was undertaken to add the patient perspective to an expert Delphi approach and an early patient cohort study. Methods A national cross-sectional study was conducted. A self-report questionnaire was published in the "Schmetterling" (Butterfly), the quarterly journal of the German SLE patient association...
January 1, 2018: Lupus
https://www.readbyqxmd.com/read/29770463/a-first-for-dermatopathology-and-pathology-in-general-appropriate-use-criteria-in-dermatopathology-from-the-american-society-of-dermatopathology
#3
Adam I Rubin, Michael Hitchcock
In this issue of the Journal of Cutaneous Pathology(1), the ASDP Appropriate Use Criteria (AUC) Task Force releases a landmark series of recommendations on AUC from the American Society of Dermatopathology. This is the first set of AUC in dermatopathology and, indeed, in pathology overall. These recommendations were developed as part of the work of the ASDP AUC Task Force, created in 2015. This publication provides strong, evidence-based recommendations that will improve the delivery and utilization of care for our patients, just as AUC for Mohs surgery have elevated the discourse on that procedure for the benefit of patients and society as a whole(2)...
May 17, 2018: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/29767439/lessons-learned-and-next-steps-for-building-knowledge-about-tribal-maternal-infant-and-early-childhood-home-visiting
#4
Corrie B Whitmore, Michelle Sarche, Cathy Ferron, John Moritsugu, Jenae G Sanchez
Authors in this Special Issue of the Infant Mental Health Journal shared the work of the first three cohorts of Tribal Maternal, Infant, and Early Childhood Home Visiting (MIECHV) grantees funded by the Administration for Children and Families. Since 2010, Tribal MIECHV grantees have served families and children prenatally to kindergarten entry in American Indian and Alaska Native (AI/AN) communities across the lower 48 United States and Alaska. Articles highlighted challenges and opportunities that arose as grantees adapted, enhanced, implemented, and evaluated their home-visiting models...
May 16, 2018: Infant Mental Health Journal
https://www.readbyqxmd.com/read/29762119/hip-fracture-mortality-differences-between-intertrochanteric-and-femoral-neck-fractures
#5
Nicholas B Frisch, Nolan Wessell, Michael Charters, Alexander Greenstein, Jonathan Shaw, Edward Peterson, S Trent Guthrie
The purpose of this study was to identify the specific risk factors that affect mortality in patients with hip fractures and differentiate mortality-associated factors between intertrochanteric (IT) and femoral neck (FN) fractures. A total of 1538 consecutive patients with hip fractures were treated at the authors' institution between January 2005 and October 2013. Ultimately 858 IT and 479 FN fracture patients were included on the basis of age >60 years with an isolated hip fracture. Mortality rate at 90 days was 12...
2018: Journal of Surgical Orthopaedic Advances
https://www.readbyqxmd.com/read/29761775/-the-role-of-the-food-and-drug-administration-as-times-change
#6
Niels Keiding
The prestigious journal Biostatistics published in July 2017 six solicited commentaries on the role of the U.S. Food and Drug Administration (FDA), as times change, with ever developing technical tools for clinical trials and their evaluation, with increased focus on personalised medicine (possibly aided by genetic testing), and on patient self-determination. Two were written by American economists, four by leading biostatisticians, mostly from the USA. This paper summarises these texts for a Danish audience...
May 7, 2018: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/29755907/the-100-most-influential-papers-and-recent-trends-in-the-field-of-gastrointestinal-stromal-tumours-a-bibliometric-analysis
#7
Khadijah Siddiq, Hira F Akbar, Meeshal Khan, Amna A Siddiqui, Salman Nusrat, Jean Y Blay
Background Bibliometric analysis is a statistical tool used to examine the exponential growth in medical research. Many analogous analyses have been conducted, but none existed for gastrointestinal stromal tumors (GISTs). Hence, we conducted a citation analysis of the hundred most cited and recently published articles on this topic. Methods Scopus was chosen as the primary database, through which the top 100 and recent publications were ranked according to the citation count and were then analysed. Results The 100 most cited articles were published between 1992 and 2013, among which the greatest number of articles were published in the years 2002 (n = 15) and 2006 (n = 11)...
March 12, 2018: Curēus
https://www.readbyqxmd.com/read/29752897/ajo-centennial-the-influence-of-early-ophthalmic-hospitals-on-the-journal
#8
Akhilesh S Pathipati, James C Tsai
PURPOSE: To consider the American Journal of Ophthalmology's role as not only a forum to describe clinical and scientific advances but also as a record of institutional histories. We used the New York Eye and Ear Infirmary of Mount Sinai, the Massachusetts Eye and Ear Infirmary, and the Wills Eye Hospital as case studies on the journal's role in documenting the people and organizations that have moved ophthalmology forward. DESIGN: Perspective METHODS: Using the ScienceDirect database, we conducted a literature search to gather all mentions of the three eye hospitals in the journal's archives from 1918 to 2018...
May 9, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29750828/romosozumab-frame-study-a-post-hoc-analysis-of-the-role-of-regional-background-fracture-risk-on-nonvertebral-fracture-outcome
#9
Felicia Cosman, Daria B Crittenden, Serge Ferrari, E Michael Lewiecki, Juan Jaller-Raad, Cristiano Zerbini, Cassandra E Milmont, Paul D Meisner, Cesar Libanati, Andreas Grauer
In the pivotal Fracture Study in Postmenopausal Women with Osteoporosis (FRAME; NCT01575834), 1 year of the bone-forming agent romosozumab significantly reduced new vertebral and clinical fracture risk versus placebo. Nonvertebral fracture risk was not significantly reduced in the overall population, influenced by a low placebo-group fracture rate, observed particularly in the highest-enrolling region of Latin America. In year 1 of FRAME, postmenopausal women with a T-score of -2.5 to -3.5 at the total hip or femoral neck were randomized to subcutaneous romosozumab 210 mg or placebo once monthly for 12 months...
May 11, 2018: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/29745694/the-ab-normal-social-personality-catena-exploring-the-journal-of-abnormal-and-social-psychology-during-the-interwar-years
#10
Ian J Davidson
This article is a cocitation network analysis of The Journal of Abnormal and Social Psychology ( JASP ) from 1925 to 1942. The analysis was conducted to help shed light on the historical roots of the intellectual and institutional relationships among social, personality, and abnormal psychology. JASP was a main venue for the boundary work of early- to mid-twentieth-century American psychologists. One of the main goals of these various research communities was to appropriate psychoanalytic and sociological concepts into preferred methods and approaches that favored an individualistic, quantifiable, and ultimately normal subject...
May 2018: History of Psychology
https://www.readbyqxmd.com/read/29745246/chaco-canyon-dig-unearths-ethical-concerns
#11
Katrina G Claw, Dorothy Lippert, Jessica Bardill, Anna Cordova, Keolu Fox, Joseph M Yracheta, Alyssa C Bader, Deborah A Bolnick, Ripan S Malhi, Kimberly TallBear, Nanibaa' A Garrison
The field of paleogenomics (the study of ancient genomes) is rapidly advancing, with more robust methods of isolating ancient DNA and increasing access to next-generation DNA sequencing technology. As these studies progress, many important ethical issues have emerged that should be considered when ancient Native American remains, whom we refer to as ancestors, are used in research. We highlight a 2017 article by Kennett et al., "Archaeogenomic evidence reveals prehistoric matrilineal dynasty," that brings to light several ethical issues that should be addressed in paleogenomics research...
July 2017: Human Biology
https://www.readbyqxmd.com/read/29742375/investigational-testing-for-zika-virus-among-u-s-blood-donors
#12
MULTICENTER STUDY
Paula Saá, Melanie Proctor, Gregory Foster, David Krysztof, Colleen Winton, Jeffrey M Linnen, Kui Gao, Jaye P Brodsky, Ronald J Limberger, Roger Y Dodd, Susan L Stramer
BACKGROUND: Because of the potential severe clinical consequences of Zika virus (ZIKV) infection, the large numbers of asymptomatic travelers returning from ZIKV-active areas, the detection of ZIKV nucleic acid in blood, and reports of transmission of ZIKV through transfusion, in 2016 the Food and Drug Administration released recommendations for individual-unit nucleic acid testing to minimize the risk of transmission of ZIKV through blood transfusions. METHODS: The American Red Cross implemented investigational screening of donated blood for ZIKV RNA by means of transcription-mediated amplification (TMA)...
May 10, 2018: New England Journal of Medicine
https://www.readbyqxmd.com/read/29742290/contextual-issues-for-implementation-and-evaluation-of-home-visitation-programs-for-american-indian-and-alaska-native-communities-an-introduction-to-the-tribal-maternal-infant-and-early-childhood-home-visiting-program
#13
EDITORIAL
Douglas Novins, Aleta Meyer, Moushumi Beltangady
Home-visiting programs have become a key component of evidence-based services for pregnant women, new mothers, their infants, and their families. When Congress authorized the Maternal Infant and Early Childhood Home Visiting Program (MIECHV) in 2010, it set aside 3% of the $1.5 billion in funding to support home-visiting programs operated by tribes, Tribal MIECHV programs have been funded in 14 states and have served over 3,100 families, providing nearly 55,000 home visits to families at risk for poor child, maternal, and family outcomes...
May 9, 2018: Infant Mental Health Journal
https://www.readbyqxmd.com/read/29742281/analyzing-the-clinical-actionability-of-germline-pharmacogenomic-findings-in-oncology
#14
Rebecca Wellmann, Brittany A Borden, Keith Danahey, Rita Nanda, Blase N Polite, Walter M Stadler, Mark J Ratain, Peter H O'Donnell
BACKGROUND: Germline and tumor pharmacogenomics impact drug responses, but germline markers less commonly guide oncology prescribing. The authors hypothesized that a critical number of clinically actionable germline pharmacogenomic associations exist, representing clinical implementation opportunities. METHODS: In total, 125 oncology drugs were analyzed for positive germline pharmacogenomic associations in journals with impact factors ≥5. Studies were assessed for design and genotyping quality, clinically relevant outcomes, statistical rigor, and evidence of drug-gene effects...
May 9, 2018: Cancer
https://www.readbyqxmd.com/read/29741746/steps-to-achieve-universal-suicide-screening-in-emergency-departments-a-call-to-action
#15
Michelle Heyland, Kathleen R Delaney, Mona Shattell
American individuals attempt suicide at alarmingly high rates of approximately 1.1 million times per year. Yet the United States has failed to adopt a systematic approach to suicide prevention, particularly via universal screening. Given the increasing number of individuals with suicidal ideation presenting to emergency departments (EDs), all patients who present to the ED for treatment should be screened, as opposed to only individuals with mental health complaints. In the current article, barriers to suicide screening in the ED are discussed, as well as strategies to move ED providers toward the goal of universal screening...
May 8, 2018: Journal of Psychosocial Nursing and Mental Health Services
https://www.readbyqxmd.com/read/29741567/a-matter-of-survival-the-detrimental-consequences-of-adverse-early-life-conditions
#16
Susanne R de Rooij
Studies across different species have shown that moderate dietary restriction is associated with longer lifespan. Surprisingly however, when diet is restricted in prenatal life, the effect is completely the opposite. Animal work and human epidemiologic data have shown that undernutrition in utero negatively affects health in later life and reduces lifespan considerably. In this issue of the American Journal of Epidemiology, Schoeps et al. provide new evidence that variations in nutritional conditions during pregnancy relate to the future health of the unborn child (1)...
May 5, 2018: American Journal of Epidemiology
https://www.readbyqxmd.com/read/29731421/uncited-research-articles-in-popular-united-states-general-radiology-journals
#17
Andrew B Rosenkrantz, Ryan Chung, Richard Duszak
RATIONALE AND OBJECTIVES: This study aimed to characterize articles in popular general radiology journals that go uncited for a decade after publication. METHODS: Using the Web of Science database, we identified annual citation counts for 13,459 articles published in Radiology, American Journal of Roentgenology, and Academic Radiology between 1997 and 2006. From this article cohort, we then identified all original research articles that accrued zero citations within a decade of publication...
May 3, 2018: Academic Radiology
https://www.readbyqxmd.com/read/29727398/work-ability-trajectories-and-retirement-pathways-a-longitudinal-analysis-of-older-american-workers
#18
Michael Boissonneault, Joop de Beer
OBJECTIVE: To determine whether older workers who follow different work ability (WA) trajectories tend to follow different retirement pathways. METHODS: Nationally representative data on Americans born between 1943 and 1948. Latent class growth modelling to estimate trajectories of work ability between ages 53-54 and 65-66. Multinomial log-linear models to assess the association between WA trajectories and retirement pathways. RESULTS: Three WA trajectories were identified: high (74%), declining (17%) and low (9%)...
May 2, 2018: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29724430/acr-appropriateness-criteria-%C3%A2-hematuria-child
#19
Jonathan R Dillman, Cynthia K Rigsby, Ramesh S Iyer, Adina L Alazraki, Sudha A Anupindi, Brandon P Brown, Sherwin S Chan, Scott R Dorfman, Richard A Falcone, Matthew D Garber, Jie C Nguyen, Craig A Peters, Nabile M Safdar, Andrew T Trout, Boaz K Karmazyn
Hematuria is the presence of red blood cells in the urine, either visible to the eye (macroscopic hematuria) or as viewed under the microscope (microscopic hematuria). The clinical evaluation of children and adolescents with any form of hematuria begins with a meticulous history and thorough evaluation of the urine. The need for imaging evaluation depends on the clinical scenario in which hematuria presents, including the suspected etiology. Ultrasound and CT are the most common imaging methods used to assess hematuria in children, although other imaging modalities may be appropriate in certain instances...
May 2018: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/29724429/acr-appropriateness-criteria-%C3%A2-headache-child
#20
Laura L Hayes, Susan Palasis, Twyla B Bartel, Timothy N Booth, Ramesh S Iyer, Jeremy Y Jones, Nadja Kadom, Sarah S Milla, John S Myseros, Ann Pakalnis, Sonia Partap, Richard L Robertson, Maura E Ryan, Gaurav Saigal, Bruno P Soares, Aylin Tekes, Boaz K Karmazyn
Headaches in children are not uncommon and have various causes. Proper neuroimaging of these children is very specific to the headache type. Care must be taken to choose and perform the most appropriate initial imaging examination in order to maximize the ability to properly determine the cause with minimum risk to the child. This evidence-based report discusses the different headache types in children and provides appropriate guidelines for imaging these children. The American College of Radiology Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidisciplinary expert panel...
May 2018: Journal of the American College of Radiology: JACR
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