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Geun Yeol Bae, Joong Tark Han, Giwon Lee, Siyoung Lee, Sung Won Kim, Sangsik Park, Jimin Kwon, Sungjune Jung, Kilwon Cho
Human skin imperfectly discriminates between pressure and temperature stimuli under mixed stimulation, and exhibits nonlinear sensitivity to each stimulus. Despite great advances in the field of electronic skin (E-skin), the limitations of human skin have not previously been overcome. For the first time, the development of a stimulus-discriminating and linearly sensitive bimodal E-skin that can simultaneously detect and discriminate pressure and temperature stimuli in real time is reported. By introducing a novel device design and using a temperature-independent material, near-perfect stimulus discriminability is realized...
September 14, 2018: Advanced Materials
Glynis Ablon
Objective: The purpose of this study was to evaluate the efficacy and safety of an automated microneedling device (Exceed, Amiea Med, MT.DERM GmbH, Berlin, Germany) when used for the rejuvenation of facial skin, as well as to generate data for an FDA 510K submission for the device. Study design: This was an open-label, single-center study. Participants: Forty-eight subjects aged 35 to 75 years with signs of facial skin aging were recruited. After consenting and satisfying inclusion criteria, each subject underwent four microneedling sessions 30 days apart...
August 2018: Journal of Clinical and Aesthetic Dermatology
Shehnaz Zulfikar Arsiwala
Volumetric rejuvenation with fillers is a minimally invasive technique used for facial volume restoration. Volume restoration demands adequate knowledge of fat pads and vascularity of the face and the understanding of the depletion patterns. Volumetric restoration with injectable has witnessed a paradigm shift in the last decade with a global rejuvenation, acquiring a predominant emphasis over focal wrinkle filling to restore the depletion pattern of facial fat layers. The techniques used to achieve optimal restoration of facial volume revolve around zonal lifting and tenting, and the impact of treatment on one zone of the surrounding zones is crucial...
April 2018: Journal of Cutaneous and Aesthetic Surgery
Yimeng Sun, Yao-Jia Luo, Zhengxiu Li, Ai Jiao Yu, Lin Gong, Yuan Hong Li
BACKGROUND AND OBJECTIVES: Fractional radiofrequency (FRF) has been used in the treatment of photoaged skin for a long time. This study was intended to examine the efficacy and safety of electrode pin FRF in the treatment of photoaged skin in Chinese patients. MATERIALS AND METHODS: Twenty healthy Chinese subjects with facial photoaged skin were enrolled in this study. Each subject received three FRF treatments at 4-week intervals. Changes of photoaging were analyzed by a global evaluation, subjective Assessment, a Mexameter, and VISIA...
September 12, 2018: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
Li Lin, Bing Deng, Jingyu Sun, Hailin Peng, Zhongfan Liu
Graphene, in its ideal form, is a two-dimensional (2D) material consisting of a single layer of carbon atoms arranged in a hexagonal lattice. The richness in morphological, physical, mechanical, and optical properties of ideal graphene has stimulated enormous scientific and industrial interest, since its first exfoliation in 2004. In turn, the production of graphene in a reliable, controllable, and scalable manner has become significantly important to bring us closer to practical applications of graphene. To this end, chemical vapor deposition (CVD) offers tantalizing opportunities for the synthesis of large-area, uniform, and high-quality graphene films...
September 12, 2018: Chemical Reviews
Ilekuttige Priyan Shanura Fernando, Kil-Nam Kim, Daekyung Kim, You-Jin Jeon
The cosmetics industry is one of the most profitable in the world today. This multi-billion-dollar industry has a profound sociological impact worldwide. Its influence is global, with most individuals being concerned with conserving their physical appearance, beauty, and youth. The consumers' desire for novel, better, and safer products has stimulated the utilization of natural-product-based cosmeceutical formulations over synthetic chemicals. With remarkable advancements in marine bioresource technology, algal polysaccharides have gained much attention as bioactive ingredients in cosmeceuticals...
September 9, 2018: Critical Reviews in Biotechnology
Elena Fedyakova, Ander Pino, Lidiya Kogan, Charusa Eganova, María Troya, Eduardo Anitua
BACKGROUND: The aging process affects all organs of the body, but the skin is the most visible indicator with a great psychosocial impact. As a consequence, many skin anti-aging strategies have been developed to minimize, postpone, and even reverse the aging process. Growth factors have been widely studied in skin wound healing as these polypeptides play an essential role in the complex process of tissue regeneration. Recently, a novel 3D injectable gel based on the autologous technology platelet rich in growth factor has been described...
September 8, 2018: Journal of Cosmetic Dermatology
Jong Seo Kim
Background: Volume restoration using filler in the dorsum of the hand is a simple and effective procedure to improve wrinkles and to hide veins and tendons. Currently, Calcium-Hydroxyapatite (CaHA)-filler is the only FDA-accepted material to use in the hand dorsum. However, it is not easy to inject due to swelling and redness. In addition, hand anatomy through sonography is wrongly described in PRS. Through incorrect anatomy, physicians will make erroneous surgeries. Objectives: CaHA-filler and HA-filler were both injected into the hand to compare intra-individually the effect of each filler...
September 5, 2018: Aesthetic Surgery Journal
Sudip Saha, Yuting Chan, Leyla Soleymani
Photoelectrochemical (PEC) biosensors, with optical biasing and electrochemical readout, are expected to enhance the limit-of-detection of electrochemical biosensors by lowering their background signals. However, when PEC transducers are functionalized with biorecognition layers, their current significantly decreases, which reduces their signal-to-noise ratio and dynamic range. Here, we develop and investigate a wrinkled conductive scaffold for loading photoactive quantum dots into an electrode. The wrinkled photoelectrodes demonstrate an order of magnitude enhancement in the magnitude of the transduced PEC current compared to their planar counterparts...
September 7, 2018: ACS Applied Materials & Interfaces
Frederic Flament, David Amar, Charlotte Feltin, Roland Bazin
BACKGROUND: The alterations of some facial characteristics, with age, in men of different ethnic groups is a scarcely studied topic. OBJECTIVE: To illustrate and grade, among men of four different ethnic descents (Asians, African-Americans, Caucasians, Indians), aged 18-80 y, the changes in the severity of some facial signs occurring with age. METHODS: Digital Photographs (full face, profile, 45°) of 1058 subjects were taken under standard conditions of lightning...
September 7, 2018: International Journal of Cosmetic Science
Shu-Ichiro Fukushima, Makoto Yonetsu, Takeshi Yasui
Skin wrinkling is a typical symptom of cutaneous photoaging; however, the skin wrinkling depends on not only the actual age but also exposure history to ultraviolet B (UVB) rays in individuals. Therefore, there is considerable need for its assessment technique in vivo in skin cosmetics and antiaging dermatology. Wrinkles always appear as linear grooves in the skin, and dermal collagen fibers play an important role to determine the morphology and mechanical properties of the skin. Therefore, an optical probe sensitive to dermal collagen fiber and its orientation will be useful...
September 2018: Journal of Biomedical Optics
Jarkko Tolvanen, Jari Hannu, Heli Jantunen
Stretchable and wearable strain sensors have been intensively studied in recent years for applications in human motion monitoring. However, achieving a high-performance strain sensor with high stretchability, ultra-sensitivity, and functionality, such as tunable sensing ranges and sensitivity to various stimuli, has not yet been reported, even though such sensors have great importance for the future applications of wearable electronics. Herein, a novel and versatile strain sensor based on a cracking (silver ink patterned silicone elastomer)-(silver plated nylon structure) (Ag-DS/CF) has been designed and fabricated...
September 5, 2018: Scientific Reports
Kareem Morsy, Fathy Abdel-Ghaffar, Abdel-Rahman Bashtar, Saad Bin Dajem, Rewaida Abdel-Gaber, Marwa Mostafa
This report introduced the description of two different species of digenean parasites isolated from the intestine of Rhinopoma hardwickii with new host and locality records in Egypt. The recovered helminthes were studied morphologically and morphometrically by light microscopy and the surface topography of the two species was elucidated by scanning electron microscopy (SEM). Urotrema scabridum had an elongated body, testes were tandem, ovaries were pretesticular, and vitelline follicles were observed in 2 lateral fields...
August 30, 2018: Revista Brasileira de Parasitologia Veterinária, Brazilian Journal of Veterinary Parasitology
Seon-Hui Jang, Soo-Joung Park, Chang-Jin Lee, Dong-Kuk Ahn, Seong-Kyu Han
Botulinum toxin type A (BoNT/A) has been used therapeutically for various conditions including dystonia, cerebral palsy, wrinkle, hyperhidrosis and pain control. The substantia gelatinosa (SG) neurons of the trigeminal subnucleus caudalis (Vc) receive orofacial nociceptive information from primary afferents and transmit the information to higher brain center. Although many studies have shown the analgesic effects of BoNT/A, the effects of BoNT/A at the central nervous system and the action mechanism are not well understood...
September 2018: Korean Journal of Physiology & Pharmacology
Joo-Myung Moon, Se-Ho Park, Kwang-Hwan Jhee, Seun-Ah Yang
Tricin, a flavone found mainly in rice bran and sugarcane, has various beneficial effects. It has proven to be a clinically safe and selective potent inhibitor of different cancer cell lines. In this study, we evaluated the efficacy of enzyme-treated Zizania latifolia (ETZL) and its major active compound tricin on skin photoaging in SKH-1 hairless mice. Tricin (0.3 mg/kg) and ETZL (50, 150, and 300 mg/kg) were orally administrated to mice for 14 weeks; no cytotoxicity was observed during the entire experimental period...
September 4, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
Eunson Hwang, Pei Lin, Hien T T Ngo, Tae-Hoo Yi
Syzygium aromaticum L., commonly named clove, is widely used in the food industry due to its antioxidant and antibacterial capabilities. However, little information is available regarding its role in resisting skin photoaging. This study investigated 50% ethanol extract of Syzygium aromaticum L. (SA) and eugenol (EO) for anti-aging effects in UVB-irradiated normal human dermal fibroblasts (NHDFs) and hairless mice. In vitro, SA and EO suppressed matrix metalloproteinase-1, 3 (MMP-1 and MMP-3) secretion as well as the activator protein 1 (AP-1) phosphorylation...
September 4, 2018: Food & Function
Mina Volić, Ivana Pajić-Lijaković, Verica Djordjević, Zorica Knežević-Jugović, Ilinka Pećinar, Zora Stevanović-Dajić, Đorđe Veljović, Miroslav Hadnadjev, Branko Bugarski
Preparation of alginate-soy protein isolate (AL/SPI) complex beads containing essential oil of thyme was carried out by emulsification of thyme oil in aqueous sodium alginate solution blended with SPI solution, followed by atomization via electrostatic extrusion and gelification with calcium ions. The process parameters were optimized by variation of the alginate (1-2.5 wt.%) and SPI (0-1.5 wt.%) concentrations. Dry alginate-SPI particles exhibited wrinkle surface while shape distortion of hydrogel beads occurred with ≥1...
November 15, 2018: Carbohydrate Polymers
Hye-Na Kim, Dengteng Ge, Elaine Lee, Shu Yang
Composite films consisting of wrinkles on top of the elastomeric poly(dimethylsiloxane) film and a thin layer of silica particles embedded at the bottom is prepared as on-demand mechanoresponsive smart windows. By carefully varying the wrinkle geometry, silica particle size, and stretching strain, different initial optical states and a large degree of optical transmittance change in the visible to near infrared range with a relatively small strain (as small as 10%) is achieved. The 10% pre-strain sample has shallow wrinkles with a low amplitude and shows moderate transmittance (60...
September 2, 2018: Advanced Materials
S Rahrovan, F Fanian, P Mehryan, P Humbert, A Firooz
Introduction: The skin is important for the perception of health and beauty. Knowledge of the physiological, chemical, and biophysical differences between the skin of male and female patients helps dermatologists develop a proper approach not only for the management of skin diseases but also to properly take care of cosmetic issues. The influence of genetic and environmental factors on skin characteristics is also critical to consider. Methods: A literature search of PubMed and Google was conducted to compare the biophysical and biomechanical properties of the skin of male and female patients using the keywords "skin", "hydration", "water loss", "sebum", "circulation", "color", "thickness", "elasticity", "pH", "friction", "wrinkle", "sex", "male", and "female"...
September 2018: International Journal of Women's Dermatology
Ben-Hong Xu, Ya-Qin Lu, Zhi-Wei Ye, Qian-Wang Zheng, Tao Wei, Jun-Fang Lin, Li-Qiong Guo
In this research, a strain with broad-spectrum antimicrobial activities was isolated from the gastrointestinal tract of hairtail (Trichiurus haumela) and identified as Bacillus siamensis JFL15 through morphological, 16S rRNA, and average nucleotide identity analyses. The genome of B. siamensis JFL15 was sequenced, and three gene clusters involved in the biosynthesis of surfactin (srf), bacillibactin (dhb), and fengycin (fen) were predicted through antiSMASH analysis. The combined genomics-metabolics profiling of the strain revealed 20 active compounds, which belong to four main types of cyclic lipopeptides produced by Bacillus species: bacillibactin, iturin, fengycin, and surfactin...
2018: PloS One
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