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Knowledge based treatment planning

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https://www.readbyqxmd.com/read/29330835/international-guidelines-for-groin-hernia-management
#1
(no author information available yet)
INTRODUCTION: Worldwide, more than 20 million patients undergo groin hernia repair annually. The many different approaches, treatment indications and a significant array of techniques for groin hernia repair warrant guidelines to standardize care, minimize complications, and improve results. The main goal of these guidelines is to improve patient outcomes, specifically to decrease recurrence rates and reduce chronic pain, the most frequent problems following groin hernia repair. They have been endorsed by all five continental hernia societies, the International Endo Hernia Society and the European Association for Endoscopic Surgery...
January 12, 2018: Hernia: the Journal of Hernias and Abdominal Wall Surgery
https://www.readbyqxmd.com/read/29328050/threshold-driven-optimization-for-reference-based-auto-planning
#2
Troy Long, Mingli Chen, Steve B Jiang, Weiguo Lu
We study threshold-driven optimization methodology for automatically generating a treatment plan that is motivated by a reference DVH for IMRT treatment planning. We present a framework for threshold-driven optimization for reference-based auto-planning (TORA). Commonly used voxel-based quadratic penalties have two components for penalizing under- and over-dosing of voxels: a reference dose threshold and associated penalty weight. Conventional manual- and auto-planning using such a function involves iteratively updating the preference weights while keeping the thresholds constant, an unintuitive and often inconsistent method for planning toward some reference DVH...
January 12, 2018: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29317383/research-and-practice-based-nutrition-education-and-cooking-workshops-in-pediatric-oncology-protocol-for-implementation-and-development-of-curriculum
#3
Cynthia Chaput, Sabrina Beaulieu-Gagnon, Véronique Bélanger, Simon Drouin, Laurence Bertout, Lucie Lafrance, Cinthia Olivier, Marthe Robitaille, Caroline Laverdière, Daniel Sinnett, Marie Marquis, Valérie Marcil
BACKGROUND: Progresses in childhood cancer treatment, diagnosis, and management have resulted in childhood cancer survival rates of over 80%. However, this therapeutic success comes with a heavy price: two-thirds of childhood cancer survivors will be affected by further complications, including cardiovascular and metabolic diseases. Adequate nutrition during cancer treatment is essential to ensure the child's optimal development, improve tolerance to treatments, and can contribute to lower the risk of developing cardiometabolic diseases...
January 9, 2018: JMIR Research Protocols
https://www.readbyqxmd.com/read/29314480/preliminary-assessment-of-the-computer-based-taenia-solium-educational-program-the-vicious-worm-on-knowledge-uptake-in-primary-school-students-in-rural-areas-in-eastern-zambia
#4
Emma C Hobbs, Kabemba Evans Mwape, Inge Van Damme, Dirk Berkvens, Gideon Zulu, Moses Mambwe, Mwelwa Chembensofu, Isaac Khozozo Phiri, Maxwell Masuku, Emmanuel Bottieau, Brecht Devleesschauwer, Niko Speybroeck, Angela Colston, Pierre Dorny, Arve Lee Willingham, Sarah Gabriël
OBJECTIVE: The zoonotic helminth Taenia solium is endemic in Zambia, causing human (taeniasis and (neuro)cysticercosis) and pig (porcine cysticercosis) diseases with high health, social and economic burdens. We aimed to evaluate the impact of a health educational program intended to lead to powerful and cumulative improvements in knowledge, attitudes and practices that decrease parasite transmission and disease occurrence. METHODS: Half-day health education workshops were conducted in three primary schools in the highly endemic Eastern Province of Zambia, using the computer-based T...
January 4, 2018: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/29302532/does-being-under-treatment-improve-knowledge-attitude-practice-for-hypertension-a-hospital-based-study-from-north-india
#5
Rajiv Kumar Gupta, Shahid Hussain, Zahida Parveen, Sunil Kumar Raina, Bhavna Langer, Rashmi Kumari
Background: Studies suggest that approximately half of patients with raised blood pressure (BP) are undetected, that half of those detected are not treated, and that half of those treated are not controlled, famously described as the "rule of halves." Importantly, the cornerstone of the primary prevention of cardiovascular diseases is early detection and drug treatment (antihypertensive) of patients with high BP. Studies across populations in developed world have shown that awareness and management of high BP levels are far from optimal...
April 2017: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/29300204/the-association-between-the-severity-and-level-of-understanding-of-depression-among-patients-treated-with-antidepressants-a-survey-of-424-outpatients-in-japan
#6
Tetsu Tomita, Norio Yasui-Furukori, Shuhei Kudo, Norio Sugawara, Akira Fujii, Koji Tsuruga, Yasushi Sato, Masamichi Ishioka, Kazuhiko Nakamura
OBJECTIVES: The present study investigated the association between the severity and knowledge of depression and attempted to reveal the specific aspects of understanding associated with severity. METHODS: A total of 424 outpatients were enrolled in this study. We used an original self-administered questionnaire: (a) the symptoms of depression, (b) the course of depression, (c) the cause of depression, (d) the treatment plan, (e) the duration of antidepressant use, (f) how to discontinue antidepressant use, (g) the adverse effects of antidepressants, and (h) psychotherapy...
January 3, 2018: Clinical Neuropharmacology
https://www.readbyqxmd.com/read/29284718/cohort-profile-study-of-transition-outcomes-and-gender-strong-to-assess-health-status-of-transgender-people
#7
Virginia P Quinn, Rebecca Nash, Enid Hunkeler, Richard Contreras, Lee Cromwell, Tracy A Becerra-Culqui, Darios Getahun, Shawn Giammattei, Timothy L Lash, Andrea Millman, Brandi Robinson, Douglas Roblin, Michael J Silverberg, Jennifer Slovis, Vin Tangpricha, Dennis Tolsma, Cadence Valentine, Kevin Ward, Savannah Winter, Michael Goodman
PURPOSE: The Study of Transition, Outcomes and Gender (STRONG) was initiated to assess the health status of transgender people in general and following gender-affirming treatments at Kaiser Permanente health plans in Georgia, Northern California and Southern California. The objectives of this communication are to describe methods of cohort ascertainment and data collection and to characterise the study population. PARTICIPANTS: A stepwise methodology involving computerised searches of electronic medical records and free-text validation of eligibility and gender identity was used to identify a cohort of 6456 members with first evidence of transgender status (index date) between 2006 and 2014...
December 27, 2017: BMJ Open
https://www.readbyqxmd.com/read/29261818/update-in-hospital-palliative-care-symptom-management-communication-caregiver-outcomes-and-moral-distress
#8
Rachel D Havyer, Daniel H Pomerantz, Robert L Jayes, Patricia F Harris, Stephanie M Harman, Aziz A Ansari
BACKGROUND: Updated knowledge of the palliative care (PC) literature is needed to maintain competency and best address the PC needs of hospitalized patients. We critiqued the recent PC literature with the highest potential to impact hospital practice. METHODS: We reviewed articles published between January 2016 and December 2016, which were identified through a handsearch of leading journals and a MEDLINE search. The final 9 articles selected were determined by consensus based on scientific rigor, relevance to hospital medicine, and impact on practice...
December 20, 2017: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
https://www.readbyqxmd.com/read/29261816/improving-quality-of-care-for-seriously-ill-patients-opportunities-for-hospitalists
#9
Robin E Fail, Diane E Meier
As the shift to value-based payment accelerates, hospitals are under increasing pressure to deliver high-quality, efficient services. Palliative care approaches improve quality of life and family well-being, and in doing so, reduce resource utilization and costs. Hospitalists frequently provide palliative care interventions to their patients, including pain and symptom management and engaging in conversations with patients and families about the realities of their illness and treatment plans that align with their priorities...
December 20, 2017: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
https://www.readbyqxmd.com/read/29261346/using-the-theoretical-domains-framework-to-identify-barriers-and-enablers-to-pediatric-asthma-management-in-primary-care-settings
#10
Janet Yamada, Melissa L Potestio, Andrew J Cave, Heather Sharpe, David W Johnson, Andrea M Patey, Justin Presseau, Jeremy M Grimshaw
OBJECTIVES: This study aimed to apply a theory-based approach to identify barriers and enablers to implementing the Alberta Primary Care Asthma Pediatric Pathway (PCAPP) into clinical practice. Phase 1 included an assessment of assumptions underlying the intervention from the perspectives of the developers. Phase 2 determined the perceived barriers and enablers for: 1) primary care physicians' prescribing practices, 2) allied health care professionals' provision of asthma education to parents, and 3) children and parents' adherence to their treatment plans...
December 20, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29261024/toward-patient-centered-outcomes-for-cognitive-evaluations-the-perspective-of-those-affected-by-parkinson-s-disease
#11
Jared F Benge, Teresa Heemsbergen, Ronald A Nelson, David O Konesheck, Bonny Konesheck, Charles S Aaron
OBJECTIVE: Patient-centered outcomes research is predicated on the idea that the opinions, attitudes, and preferences of patients should help inform study design and interpretation. To date, little is known about what defines patient-centered outcomes from cognitive evaluations. The current evaluation sought to explore this issue in persons with Parkinson's disease (PwPD) and their care partners (CP). METHOD: Focus groups of 22 PwPD/CP dyads were conducted to identify potential consumer oriented endpoints from cognitive evaluations...
December 20, 2017: Clinical Neuropsychologist
https://www.readbyqxmd.com/read/29259567/using-functional-analysis-as-a-framework-to-guide-individualized-treatment-for-negative-symptoms
#12
REVIEW
Tania M Lincoln, Marcel Riehle, Matthias Pillny, Sylvia Helbig-Lang, Anne-Katharina Fladung, Matthias Hartmann-Riemer, Stefan Kaiser
Although numerous interventions are available for negative symptoms, outcomes have been unsatisfactory with pharmacological and psychological interventions producing changes of only limited clinical significance. Here, we argue that because negative symptoms occur as a complex syndrome caused and maintained by numerous factors that vary between individuals they are unlikely to be treated effectively by the present "one size fits all" approaches. Instead, a well-founded selection of those interventions relevant to each individual is needed to optimize both the efficiency and the efficacy of existing approaches...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/29258978/the-effectiveness-of-text-messaging-for-detection-and-management-of-hypertension-in-indigenous-people-in-canada-protocol-for-a-randomized-controlled-trial
#13
Karen Yeates, Norm Campbell, Marion A Maar, Nancy Perkins, Peter Liu, Jessica Sleeth, Carter Smith, Colin McAllister, Diane Hua-Stewart, George Wells, Sheldon W Tobe
BACKGROUND: Hypertension, the leading cause of morbidity and mortality, affects more than 1 billion people and is responsible globally for 10 million deaths annually. Hypertension can be controlled on a national level; in Canada, for example, awareness, treatment, and control improved dramatically from only 16% in 1990 to 66% currently. The ongoing development, dissemination, and implementation of Hypertension Canada's clinical practice guidelines is considered to be responsible, in part, for achieving these high levels of control and the associated improvements in cardiovascular outcomes...
December 19, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/29250336/preoperative-planning-for-redirective-periacetabular-osteotomies
#14
REVIEW
Christoph E Albers, Piet Rogers, Nicholas Wambeek, Sufian S Ahmad, Piers J Yates, Gareth H Prosser
Redirective, periacetabular osteotomies (PAO) represent a group of surgical procedures for treatment of developmental dysplasia of the hip (DDH) in skeletally mature and immature patients. The ultimate goal of all procedures is to reduce symptoms, improve function and delay or prevent progression of osteoarthritis. During the last two decades, the understanding of the underlying pathomechanisms has continuously evolved. This is mainly attributable to the development of the femoroacetabular impingement concept that has increased the awareness of the underlying three-dimensional complexity associated with DDH...
December 2017: Journal of Hip Preservation Surgery
https://www.readbyqxmd.com/read/29240536/dementia-awareness-campaign-in-the-latino-community-a-novel-community-engagement-pilot-training-program-with-promotoras
#15
Nusha Askari, Ann Choryan Bilbrey, Iliana Garcia Ruiz, Marika Blair Humber, Dolores Gallagher-Thompson
OBJECTIVES: To create a curriculum about Alzheimer's disease and dementia, and to train Promotoras affiliated with a local community education and health advocacy organization, in order to raise awareness and knowledge of what dementia is, and how it can be recognized, in persons of Hispanic/Latino descent. METHODS: Community based participatory research (CPBR) model was used to create materials, implement training, and engage/empower Promotoras to educate the local community...
November 21, 2017: Clinical Gerontologist
https://www.readbyqxmd.com/read/29235457/serum-metabolic-profile-alteration-reveals-response-to-platinum-based-combination-chemotherapy-for-lung-cancer-sensitive-patients-distinguished-from-insensitive-ones
#16
Shan Xu, Yanping Zhou, Hui Geng, Dandan Song, Jing Tang, Xianmin Zhu, Di Yu, Sheng Hu, Yanfang Cui
Most lung cancers are diagnosed at fairly advanced stages due to limited clinical symptoms. Platinum-based chemotherapy, either as single regimen or in combination with radiation, is one of the major recommendations for the patients. Earlier evaluation of the effectiveness of the chemotherapies is critical for developing better treatment plan given the toxicity of the chemotherapeutic reagents. Drug efficacy could be reflected in the systemic metabolism characteristics though knowledge about which remains scarce...
December 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29233111/effectiveness-of-two-community-based-strategies-on-disease-knowledge-and-health-behaviour-regarding-malaria-diarrhoea-and-pneumonia-in-ghana
#17
Blanca Escribano-Ferrer, Margaret Gyapong, Jane Bruce, Solomon A Narh Bana, Clement T Narh, Naa-Korkor Allotey, Roland Glover, Charity Azantilow, Constance Bart-Plange, Isabella Sagoe-Moses, Jayne Webster
BACKGROUND: Ghana has developed two community-based strategies that aim to increase access to quality treatment for malaria, diarrhoea and suspected pneumonia, and to improve household and family practices: integrated Community Case Management (iCCM) and Community-based Health Planning and Services (CHPS). The objective of the study was to assess the effectiveness of iCCM and CHPS on disease knowledge and health behaviour regarding malaria, diarrhoea and pneumonia. METHODS: A household survey was conducted two and eight years after implementation of iCCM in the Volta and Northern Regions of Ghana respectively, and more than ten years of CHPS implementation in both regions...
December 12, 2017: BMC Public Health
https://www.readbyqxmd.com/read/29227151/evaluating-which-plan-quality-metrics-are-appropriate-for-use-in-lung-sbrt
#18
Ravindra Yaparpalvi, Madhur K Garg, Jin Shen, William R Bodner, Dinesh K Mynampati, Aleiya Gafar, Hsiang-Chi Kuo, Amar K Basavatia, Nitin Ohri, Linda X Hong, Shalom Kalnicki, Wolfgang A Tomé
OBJECTIVES: Several dose metrics in the categories - homogeneity, coverage, conformity and gradient have been proposed in literature for evaluating treatment plan quality. In this study, we applied these metrics to characterize and identify the plan quality metrics that would merit plan quality assessment in Lung SBRT dose distributions. METHODS: Treatment plans of 90 Lung SBRT patients, comprising 91 targets, treated in our institution were retrospectively reviewed...
December 11, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/29225692/recent-advances-in-radiation-oncology
#19
REVIEW
Cristina Garibaldi, Barbara Alicja Jereczek-Fossa, Giulia Marvaso, Samantha Dicuonzo, Damaris Patricia Rojas, Federica Cattani, Anna Starzyńska, Delia Ciardo, Alessia Surgo, Maria Cristina Leonardi, Rosalinda Ricotti
Radiotherapy (RT) is very much a technology-driven treatment modality in the management of cancer. RT techniques have changed significantly over the past few decades, thanks to improvements in engineering and computing. We aim to highlight the recent developments in radiation oncology, focusing on the technological and biological advances. We will present state-of-the-art treatment techniques, employing photon beams, such as intensity-modulated RT, volumetric-modulated arc therapy, stereotactic body RT and adaptive RT, which make possible a highly tailored dose distribution with maximum normal tissue sparing...
2017: Ecancermedicalscience
https://www.readbyqxmd.com/read/29218901/using-simulation-and-optimization-approach-to-improve-outcome-through-warfarin-precision-treatment
#20
Chih-Lin Chi, Lu He, Kourosh Ravvaz, John Weissert, Peter J Tonellato
We apply a treatment simulation and optimization approach to develop decision support guidance for warfarin precision treatment plans. Simulation include the use of ∼1,500,000 clinical avatars (simulated patients) generated by an integrated data-driven and domain-knowledge based Bayesian Network Modeling approach. Subsequently, we simulate 30-day individual patient response to warfarin treatment of five clinical and genetic treatment plans followed by both individual and subpopulation based optimization. Sub-population optimization (compared to individual optimization) provides a cost effective and realistic means of implementation of a precision-driven treatment plan in practical settings...
2018: Pacific Symposium on Biocomputing
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