Zijian Lv, Lu Li, Yin Li, Lizi Zhang, Xing Guo, Caihong Huang, Wenjuan Hou, Yishan Qu, Limin Liu, Yitong Li, Zhixiong He, Fadao Tai
Male mammals display different paternal responses to pups, either attacking or killing the young offspring, or contrastingly, caring for them. The neural circuit mechanism underlying the between-individual variation in the pup-directed responsiveness of male mammals remains unclear. Monogamous mandarin voles were used to complete the present study. The male individuals were identified as paternal and infanticidal voles, according their behavioral responses to pups. It was found that the serotonin release in the medial preoptic area (MPOA), as well as the serotonergic neuron activity, significantly increased upon licking the pups, but showed no changes after attacking the pups, as revealed by the in vivo fiber photometry of the fluorescence signal from the 5-HT 1...
July 18, 2023: International Journal of Molecular Sciences