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Karl F Kowalewski, Christian Tapking, Svetlana Hetjens, Felix Nickel, Philipp Mandel, Philipp Nuhn, Manuel Ritter, Judd W Moul, Joachim W Thüroff, Maximilian C Kriegmair
CONTEXT: Vesicourethral anastomosis (VUA) is a crucial step during radical prostatectomy (RP). Generally, either a continuous (CS) or an interrupted suture (IS) is used. However, there is no clear evidence if one technique is superior to the other. OBJECTIVE: This study aimed to provide a systematic overview and comparison between IS and CS for the VUA during RP. EVIDENCE ACQUISITION: The study was conducting according to the PRISMA guidelines...
June 12, 2018: European Urology Focus
Rohan Menon, Aris Karatasakis, Siddharth Patel, Barbara A Danek, Judit Karacsonyi, Bavana V Rangan, Tayo Addo, Dharam Kumbhani, Samir Kapadia, Michael Luna, Ehtisham Mahmud, Charles Chambers, Subhash Banerjee, Emmanouil S Brilakis
BACKGROUND: There is great variability in radiation safety practices in cardiac catheterization laboratories around the world. METHODS: We performed an international online survey on radiation safety including interventional cardiologists, electrophysiologists, interventional radiologists, and vascular surgeons. RESULTS: A total of 570 responses were received from various geographic locations, including the United States (77.9%), Asia (7.9%), Europe (6...
June 15, 2018: Journal of Invasive Cardiology
Dai Kimura, Jordy Saravia, Sridhar Jaligama, Isabella McNamara, Luan D Vu, Ryan D Sullivan, Salvatore Mancarella, Dahui You, Stephania A Cormier
Pulmonary hypertension (PH) has been observed in up to 75% of infants with moderate to severe respiratory syncytial virus (RSV) bronchiolitis and is associated with significant morbidity and mortality in infants with congenital heart disease. The purpose of this study was to establish a mouse model of PH secondary to RSV bronchiolitis that mimics the disease etiology as it occurs in infants. Neonatal mice were infected with RSV at 5 days of age, and then re-infected 4 weeks later. Serum free medium was administered to age-matched mice as control...
June 15, 2018: American Journal of Physiology. Heart and Circulatory Physiology
Roxana Moayedifar, Andreas Zuckermann, Arezu Aliabadi-Zuckermann, Julia Riebandt, Philipp Angleitner, Kamen Dimitrov, Thomas Schloeglhofer, Angela Rajek, Guenther Laufer, Daniel Zimpfer
OBJECTIVES: Fixed pulmonary hypertension (fPH) is a contraindication for heart transplantation (HTX). Left ventricular assist device (LVAD) implantation as a bridge to candidacy can reverse fPH in patients with terminal heart failure by chronic left ventricular unloading. We report our institutional experience with terminal heart failure patients and fPH that were successfully bridged to candidacy and underwent subsequent HTX. METHODS: We retrospectively reviewed the data of 79 patients with terminal heart failure and fPH who were successfully bridged to candidacy for HTX with 6 different LVAD devices at our centre from October 1998 to September 2016 (Novacor n = 4, MicroMed DeBakey n = 29, DuraHeart n = 2, HeartMate II n = 14, HVAD n = 29 and MVAD n = 1)...
June 13, 2018: European Journal of Cardio-thoracic Surgery
Kahoru Fukuoka, Mihoko Furuichi, Kenta Ito, Yoshihiko Morikawa, Ichiro Watanabe, Naoki Shimizu, Yuho Horikoshi
OBJECTIVES: Catheter-associated urinary tract infections account for 30% of healthcare-associated infections. To date, few studies have addressed pediatric catheter-associated urinary tract infection in PICUs. The aim of our study was to assess the risk of catheter-associated urinary tract infection in relation to the duration of catheterization in the PICU. DESIGN: Retrospective cohort study. SETTING: PICU at a tertiary children's hospital...
June 13, 2018: Pediatric Critical Care Medicine
Jeffrey M Wilson, Anh T Nguyen, Alexander J Schuyler, Scott P Commins, Angela M Taylor, Thomas A E Platts-Mills, Coleen A McNamara
OBJECTIVE: Emerging evidence suggests a link between coronary artery disease and type 2 immunity. We sought to test the hypothesis that IgE sensitization to the mammalian oligosaccharide galactose-α-1,3-galactose (α-Gal)-the target allergen of delayed anaphylaxis to red meat-is associated with coronary artery disease. APPROACH AND RESULTS: Total IgE and specific IgE to α-Gal were assayed on sera from 118 subjects who presented for cardiac catheterization and underwent intravascular ultrasound...
June 14, 2018: Arteriosclerosis, Thrombosis, and Vascular Biology
Patrick Teefy, Rodrigo Bagur, Chantal Phillips, Kourosh Karimi-Shahri, John Teefy, Raksha Sule, Adam A Dempsey, Kambiz Norozi
OBJECTIVES: There are substantial potential benefits to noninvasive cardiac monitoring methods, such as electrical cardiometry (EC), over more invasive methods, including significantly reduced risk of complications, lower up-front and operational costs, ease of use, and continuous monitoring. To take advantage of these technologies, clinical equivalence to currently established methods must be determined. The authors sought to determine if the noninvasive measurement of cardiac index (CI) by EC was clinically equivalent to thermodilution (TD) in adult patients with aortic stenosis (AS)...
April 26, 2018: Journal of Cardiothoracic and Vascular Anesthesia
Farahnaz Ramezani, Mahnaz Khatiban, Farshid Rahimbashar, Ali Reza Soltanian
BACKGROUND: Bladder irrigation can be performed to prevent catheter-associated urinary tract infections (CAUTI), but its efficacy has been not reported in short-term indwelling urinary catheterization. This clinical trial aimed to examine the efficacy of bladder irrigation with normal saline solution in preventing CAUTI in comatose patients admitted to intensive care units. MATERIALS AND METHODS: Eligible patients were randomized to the experimental group or control group...
June 11, 2018: American Journal of Infection Control
Sunay Shah, Ryan Gindi, Mir B Basir, Akshay Khandelwal, Mohammad Alqarqaz, Mohammad Zaidan, Michele Voeltz, Gerald Koenig, Henry E Kim, William W O'Neill, Khaldoon Alaswad
INTRODUCTION: The purpose of the study is to develop an optimal TR-Band weaning strategy while minimizing vascular access site complications of hematoma or radial artery occlusion (RAO). METHODS: The trial was a randomized, prospective, single center study of 129 patients who underwent cardiac catheterization via the radial artery. Group A was an accelerated protocol in which weaning was initiated 20 min after sheath removal. Group B was an adjusted protocol, in which weaning was dependent on the amount of anti-platelet or anti-coagulation used...
April 14, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
Emily L Marshall, David Borrego, James C Fudge, Dhanashree Rajderkar, Wesley E Bolch
PURPOSE: To assess various computational phantom alignment techniques within Monte Carlo radiation transport models of pediatric fluoroscopically-guided cardiac interventional studies. METHODS: Logfiles, including all procedure radiation and machine data, were extracted from a Toshiba infinix-I unit in the University of Florida Pediatric Catheterization Laboratory for a cohort of 10 patients. Two different alignment methods were then tested against a ground-truth standard based upon identification of a unique anatomic reference point within images co-registered to specific irradiation events within each procedure...
June 13, 2018: Medical Physics
Martin Koestenberger, Alexander Avian, Andreas Gamillscheg, Hannes Sallmon, Gernot Grangl, Ante Burmas, Sabrina Schweintzger, Stefan Kurath-Koller, Gerhard Cvirn, Georg Hansmann
BACKGROUND: Echocardiographic determination of the RV end-systolic base/apex (RVESb/a) ratio was proposed to be of clinical value for the assessment of pulmonary arterial hypertension (PAH) in adults. HYPOTHESIS: We hypothesized that the RVES b/a ratio will be affected in children with PAH and aimed to correlate the RVES b/a ratio with conventionally used echocardiographic and hemodynamic variables, and with NYHA functional class (FC). METHODS: We first determined normal pediatric values for the RVES b/a ratio in 157 healthy children (68 male; age range: 0...
June 12, 2018: Clinical Cardiology
Yuman Lee, Hongkai Bao, Sagar Viramgama
PURPOSE: An overview of the growing health threat posed by the fungus Candida auris is provided, including a review of the literature and Centers for Disease Control and Prevention recommendations on C. auris identification, treatment, and infection control. SUMMARY: Since C. auris was first identified in Japan in 2009, cases of C. auris infection have been on the rise in several parts of the world, including the United States, where the first case was reported in 2017; as of November 2017, a total of 206 U...
June 12, 2018: American Journal of Health-system Pharmacy: AJHP
John P Reilly
This meta-analysis of randomized trials demonstrated no statistically significant difference in the incidence of MACE between patients who underwent trans-ulnar or the trans-radial cardiac catheterization. No differences in arterial access time, fluoroscopy time, and contrast load between the two groups.
June 2018: Catheterization and Cardiovascular Interventions
Victor Sam Lucas, Ivory Crittendon
Neonatal percutaneous carotid access is a safe technique that compares favorably to neonatal surgical carotid access. Mid-term ultrasound and angiographic follow after percutaneous carotid access shows 100% vessel patency rate with no severe stenoses or aneurysms detected. Mild stenosis (<12%) is frequent at follow up (35%), the clinical significance of which is unknown.
June 2018: Catheterization and Cardiovascular Interventions
Karen A Alroy, Gianfranco Arroyo, Robert H Gilman, Eloy Gonzales-Gustavson, Linda Gallegos, Cesar M Gavidia, Manuela Verastegui, Silvia Rodriguez, Teresa Lopez, Luis A Gomez-Puerta, Joseph Alroy, Hector H Garcia, Armando E Gonzalez, For The Cysticercosis Working Group In Peru
Neurocysticercosis (NCC), the infection of the human central nervous system (CNS) with larval cysts of Taenia solium causes widespread neurological morbidity. Animal models are crucial for studying the pathophysiology and treatment of NCC. Some drawbacks of current NCC models include differences in the pathogenesis of the model and wild-type parasite, low rates of infection efficiency and lack of reproducibility. We describe a novel porcine model that recreates infection in the CNS with high efficiency. Activated oncospheres, either in a high (45,000-50,000) or low (10,000) dose were inoculated in the common carotid artery of 12 pigs by ultrasound-guided catheterization...
June 11, 2018: American Journal of Tropical Medicine and Hygiene
C Linti, M Doser, H Planck, S Oberhoffner, E Mueller, M Renardy, J Biesinger, B Neumann, K Stang, T O Greiner, C Schlensak, S Krajewski, H P Wendel
Following percutaneous coronary intervention, vascular closure devices (VCDs) are increasingly used to reduce time to ambulation, enhance patient comfort, and reduce potential complications compared with traditional manual compression. Newer techniques include complicated, more or less automated suture devices, local application of pads or the use of metal clips and staples. These techniques often have the disadvantage of being time consuming, expensive or not efficient enough. The VCD failure rate in association with vascular complications of 2...
June 11, 2018: Journal of Materials Science. Materials in Medicine
Rabea Asleh, Tal Hasin, Alexandros Briasoulis, Sarah D Schettle, Barry A Borlaug, Atta Behfar, Naveen L Pereira, Brooks S Edwards, Alfredo L Clavell, Lyle D Joyce, Simon Maltais, John M Stulak, Sudhir S Kushwaha
OBJECTIVE: To investigate differences in invasive hemodynamic parameters and outcomes in patients with and without heart failure (HF) symptoms after left ventricular assist device (LVAD) implantation. PATIENTS AND METHODS: We performed a single-center retrospective analysis of 51 symptomatic patients and 50 patients with resolved HF symptoms who underwent right-sided heart catheterization (RHC) after LVAD implantation from March 1, 2007, through June 30, 2016. Patient characteristics and outcomes including all-cause mortality and right ventricular (RV) failure were compared between groups...
June 8, 2018: Mayo Clinic Proceedings
Edward Vincent S Faustino, Veronika Shabanova, Matthew G Pinto, Simon Li, Erin Trakas, Michael Miksa, Shira Gertz, Lee A Polikoff, Massimo Napolitano, Adele R Brudnicki, Joana A Tala, Cicero T Silva
OBJECTIVE: To determine the epidemiology of lower extremity deep venous thrombosis (DVT) in critically ill adolescents, which currently is unclear. STUDY DESIGN: We performed a multicenter, prospective, cohort study. Adolescents aged 13-17 years who were admitted to 6 pediatric intensive care units and were anticipated to receive cardiopulmonary support for at least 48 hours were eligible, unless they were admitted with DVT or pulmonary embolism or were receiving or anticipated to receive therapeutic anticoagulation...
June 8, 2018: Journal of Pediatrics
Alexandra Groth, Stéphanie Saxer, Patrick R Bader, Mona Lichtblau, Michael Furian, Simon R Schneider, Esther I Schwarz, Konrad E Bloch, Silvia Ulrich
BACKGROUND: There is insufficient evidence to counsel patients with pulmonary hypertension undergoing altitude or air travel. We thus aimed to study hemodynamic response of patients with pulmonary arterial or chronic thromboembolic pulmonary hypertension (PAH/CTEPH) during changes in inspiratory oxygen partial pressure. METHODS AND RESULTS: Consecutive patients undergoing right heart catheterization had hemodynamic assessments whilst breathing ambient air (normoxia, FiO2 0...
May 31, 2018: International Journal of Cardiology
Peizhe Kang
BACKGROUND: Most pulmonary arterial hypertension (PAH) biomarkers are for risk stratification and prognosis prediction. We aimed to evaluate the diagnostic value of circulating serum miR-509-3p in PAH with congenital heart disease. METHODS: Preoperative blood samples were collected from patients diagnosed as PAH to receive right ventricular catheterization. According to right ventricular catheterization results, they were divided into a control group with normal mean pulmonary artery pressure (mPAP <20 mmHg) and a PAH group (mPAP ≥25 mmHg)...
June 8, 2018: Hellenic Journal of Cardiology: HJC, Hellēnikē Kardiologikē Epitheōrēsē
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