keyword
MENU ▼
Read by QxMD icon Read
search

Arboreal behavior

keyword
https://www.readbyqxmd.com/read/28203140/tamoxifen-activation-of-cre-recombinase-has-no-persisting-effects-on-adult-neurogenesis-or-learning-and-anxiety
#1
Peter Rotheneichner, Pasquale Romanelli, Lara Bieler, Sebastian Pagitsch, Pia Zaunmair, Christina Kreutzer, Richard König, Julia Marschallinger, Ludwig Aigner, Sébastien Couillard-Després
Adult neurogenesis is a tightly regulated process continuously taking place in the central nervous system of most mammalian species. In neuroscience research, transgenic animals bearing the tamoxifen-inducible CreER(T2)-Lox system are widely used. In this study, we made use of a Nestin-CreER(T2)/R26R-YFP transgenic mouse model in which the CreER(T2) activates the expression of YFP in multipotent neural stem cells upon tamoxifen application. Humoral factors, such as the levels of estrogens, have been reported to affect the hippocampal neurogenesis...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28196398/factors-of-influence-and-social-correlates-of-parturition-in-captive-campbell-s-monkeys-case-study-and-breeding-data
#2
Alban Lemasson, Ronan Jubin, Philippe Bec, Martine Hausberger
How nonhuman primates deal with birth, at the moment of delivery, and during the following days, remains poorly explored because of the unpredictability of this event, particularly for forest-dwelling arboreal species. Available studies highlight intra- and interspecific variation which suggest flexibility of the timing of delivery, of behavior associated with labor contractions and parturition, and the social context and ambient noise surrounding delivery. Here, we present the findings of a two-decade survey of reproduction in a population of captive Campbell's monkeys...
February 14, 2017: American Journal of Primatology
https://www.readbyqxmd.com/read/28190643/left-habenula-mediates-light-preference-behavior-in-zebrafish-via-an-asymmetrical-visual-pathway
#3
Bai-Bing Zhang, Yuan-Yuan Yao, He-Fei Zhang, Koichi Kawakami, Jiu-Lin Du
Habenula (Hb) plays critical roles in emotion-related behaviors through integrating inputs mainly from the limbic system and basal ganglia. However, Hb also receives inputs from multiple sensory modalities. The function and underlying neural circuit of Hb sensory inputs remain unknown. Using larval zebrafish, we found that left dorsal Hb (dHb, a homolog of mammalian medial Hb) mediates light-preference behavior by receiving visual inputs from a specific subset of retinal ganglion cells (RGCs) through eminentia thalami (EmT)...
February 22, 2017: Neuron
https://www.readbyqxmd.com/read/28148643/developmental-nicotine-exposure-alters-potassium-currents-in-hypoglossal-motoneurons-of-neonatal-rat
#4
Marina Cholanian, Jesse Wealing, Richard B Levine, Ralph F Fregosi
We previously showed that nicotine exposure in utero and after birth via breast milk [developmental nicotine exposure (DNE)] is associated with many changes in the structure and function of hypoglossal motoneurons (XIIMNs), including a reduction in the size of the dendritic arbor and an increase in cell excitability. Interestingly, the elevated excitability was associated with a reduction in the expression of glutamate receptors on the cell body. Together, these observations are consistent with a homeostatic compensation aimed at restoring cell excitability...
February 1, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28130356/a-novel-human-camk2a-mutation-disrupts-dendritic-morphology-and-synaptic-transmission-and-causes-asd-related-behaviors
#5
Jason R Stephenson, Xiaohan Wang, Tyler L Perfitt, Walker P Parrish, Brian C Shonesy, Christian R Marks, Douglas P Mortlock, Terunaga Nakagawa, James S Sutcliffe, Roger J Colbran
: Characterizing the functional impact of novel mutations linked to autism spectrum disorder (ASD) provides a deeper mechanistic understanding of the underlying pathophysiological mechanisms. Here we show that a de novo Glu183 to Val (E183V) mutation in the CaMKIIα catalytic domain, identified in a proband diagnosed with ASD, decreases both CaMKIIα substrate phosphorylation and regulatory autophosphorylation, and that the mutated kinase acts in a dominant-negative manner to reduce CaMKIIα-WT autophosphorylation...
January 27, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28089852/dopamine-d1-receptor-agonist-treatment-attenuates-extinction-of-morphine-conditioned-place-preference-while-increasing-dendritic-complexity-in-the-nucleus-accumbens-core
#6
Kendra L Kobrin, Danielle T Arena, Stephen C Heinrichs, Olivia H Nguyen, Gary B Kaplan
The dopamine D1 receptor (D1R) has a role in opioid reward and conditioned place preference (CPP), but its role in CPP extinction is undetermined. We examined the effect of D1R agonist SKF81297 on the extinction of opioid CPP and associated dendritic morphology in the nucleus accumbens (NAc), a region involved with reward integration and its extinction. During the acquisition of morphine CPP, mice received morphine and saline on alternate days; injections were given immediately before each of eight daily conditioning sessions...
January 12, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28069946/wnt5a-is-essential-for-hippocampal-dendritic-maintenance-and-spatial-learning-and-memory-in-adult-mice
#7
Chih-Ming Chen, Lauren L Orefice, Shu-Ling Chiu, Tara A LeGates, Samer Hattar, Richard L Huganir, Haiqing Zhao, Baoji Xu, Rejji Kuruvilla
Stability of neuronal connectivity is critical for brain functions, and morphological perturbations are associated with neurodegenerative disorders. However, how neuronal morphology is maintained in the adult brain remains poorly understood. Here, we identify Wnt5a, a member of the Wnt family of secreted morphogens, as an essential factor in maintaining dendritic architecture in the adult hippocampus and for related cognitive functions in mice. Wnt5a expression in hippocampal neurons begins postnatally, and its deletion attenuated CaMKII and Rac1 activity, reduced GluN1 glutamate receptor expression, and impaired synaptic plasticity and spatial learning and memory in 3-mo-old mice...
January 24, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28069777/an-african-origin-of-the-eurylaimides-passeriformes-and-the-successful-diversification-of-the-ground-foraging-pittas-pittidae
#8
Alexandre Pedro Selvatti, Ana Galvão, Anieli Guirro Pereira, Luiz Pedreira Gonzaga, Claudia Augusta de Moraes Russo
The Eurylaimides is one of the few passerine groups with a pantropical distribution. In this study, we generated a multi-calibrated tree with 83% of eurylaimid species diversity based on 30 molecular loci. Particular attention was given to the monotypic Sapayoidae to reconstruct the biogeography of this radiation. We conducted several topological tests including nonoverlapping subsampling of the concatenated alignment and coalescent species tree reconstruction. These tests firmly placed the South American Sapayoidae as the sister group to all other Eurylaimides families (split at ∼28 Ma), with increasing branch support as highly variable sites were removed...
November 14, 2016: Molecular Biology and Evolution
https://www.readbyqxmd.com/read/28041904/long-term-high-resolution-imaging-of-developing-c-%C3%A2-elegans-larvae-with-microfluidics
#9
Wolfgang Keil, Lena M Kutscher, Shai Shaham, Eric D Siggia
Long-term studies of Caenorhabditis elegans larval development traditionally require tedious manual observations because larvae must move to develop, and existing immobilization techniques either perturb development or are unsuited for young larvae. Here, we present a simple microfluidic device to simultaneously follow development of ten C. elegans larvae at high spatiotemporal resolution from hatching to adulthood (∼3 days). Animals grown in microchambers are periodically immobilized by compression to allow high-quality imaging of even weak fluorescence signals...
January 23, 2017: Developmental Cell
https://www.readbyqxmd.com/read/28033671/visual-experience-dependent-regulation-of-neuronal-structure-and-function-by-histone-deacetylase-1-in-developing-xenopus-tectum-in-vivo
#10
Hangze Ruan, Juanmei Gao, Xianjie Qi, Yi Tao, Xia Guo, Zhaoyi Guo, Lijun Zheng, Yaling Song, Yuan Liao, Wanhua Shen
Histone deacetylase 1 (HDAC1) is thought to play pivotal roles in neurogenesis and neurodegeneration. However, the role of HDAC1 in neuronal growth and structural plasticity in the developing brain in vivo remains unclear. Here, we show that in the optic tectum of Xenopus laevis, HDAC1 knockdown dramatically decreased the frequency of AMPAR-mediated synaptic currents and increased the frequency of GABAAR-mediated currents, whereas HDAC1 overexpression significantly decreased the frequency of GABAAR-mediated synaptic currents...
December 29, 2016: Developmental Neurobiology
https://www.readbyqxmd.com/read/28003347/olfactory-bulb-deep-short-axon-cells-mediate-widespread-inhibition-of-tufted-cell-apical-dendrites
#11
Shawn D Burton, Greg LaRocca, Annie Liu, Claire E J Cheetham, Nathaniel N Urban
: In the main olfactory bulb (MOB), the first station of sensory processing in the olfactory system, GABAergic interneuron signaling shapes principal neuron activity to regulate olfaction. Lack of known selective markers for MOB interneurons has strongly impeded cell type-selective investigation of interneuron function, however. Here, we identify the first selective marker of glomerular layer-projecting deep short-axon cells (GL-dSACs) and systematically investigate the structure, abundance, intrinsic physiology, feedforward sensory input, neuromodulation, synaptic output, and functional role of GL-dSACs in the mouse MOB circuit...
December 21, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/27997694/spatial-patterning-of-excitatory-and-inhibitory-neuropil-territories-during-spinal-circuit-development
#12
Qing Yan, Lu Zhai, Bo Zhang, Julia E Dallman
To generate rhythmic motor behaviors, both single neurons and neural circuits require a balance between excitatory inputs that trigger action potentials and inhibitory inputs that promote a stable resting potential (E/I balance). Previous studies have focused on individual neurons and have shown that, over a short spatial scale, excitatory and inhibitory (E/I) synapses tend to form structured territories with inhibitory inputs enriched on cell bodies and proximal dendrites and excitatory inputs on distal dendrites...
December 20, 2016: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/27984183/repeated-prenatal-exposure-to-valproic-acid-results-in-cerebellar-hypoplasia-and-ataxia
#13
Stacey L Main, Randy J Kulesza
Autism spectrum disorder (ASD) is a developmental brain disorder characterized by restricted and repetitive patterns of behavior, social and communication defects, and is commonly associated with difficulties with motor coordination. The etiology of ASD, while mostly idiopathic, has been linked to hereditary factors and teratogens, such as valproic acid (VPA). VPA is used clinically to treat epilepsy, mood disorders, and in the prevention of migraines. The use of VPA during pregnancy significantly increases the risk of ASD in the offspring...
October 27, 2016: Neuroscience
https://www.readbyqxmd.com/read/27977132/mk-801-dizocilpine-regulates-multiple-steps-of-adult-hippocampal-neurogenesis-and-alters-psychological-symptoms-via-wnt-%C3%AE-catenin-signaling-in-parkinsonian-rats
#14
Sonu Singh, Akanksha Mishra, Neha Srivastava, Shubha Shukla
Adult hippocampal neurogenesis is directly involved in regulation of stress, anxiety, and depression that are commonly observed nonmotor symptoms in Parkinson's disease (PD). These symptoms do not respond to pharmacological dopamine replacement therapy. Excitotoxic damage to neuronal cells by N-methyl-d-aspartate (NMDA) receptor activation is also a major contributing factor in PD development, but whether it regulates hippocampal neurogenesis and nonmotor symptoms in PD is yet unexplored. Herein, for the first time, we studied the effect of MK-801, an NMDA receptor antagonist, on adult hippocampal neurogenesis and behavioral functions in 6-OHDA (6-hydroxydopamine) induced rat model of PD...
December 15, 2016: ACS Chemical Neuroscience
https://www.readbyqxmd.com/read/27940019/the-habenula-as-a-critical-node-in-chronic-stress-related-anxiety
#15
Luis R Jacinto, Rui Mata, Ashley Novais, Fernanda Marques, Nuno Sousa
The habenula is activated in response to stressful and aversive events, resulting in exploratory inhibition. Although possible mechanisms for habenula activation have been proposed, the effects of chronic stress on the habenular structure have never been studied. Herein, we assessed changes in volume, cell density and dendritic structure of habenular cells after chronic stress exposure using stereological and 3D morphological analysis. This study shows for the first time that there is a hemispherical asymmetry in the medial habenula (MHb) of the adult rat, with the right MHb containing more neurons than its left counterpart...
December 7, 2016: Experimental Neurology
https://www.readbyqxmd.com/read/27936448/flavivirus-transmission-focusing-on-zika
#16
REVIEW
Nikos Vasilakis, Scott C Weaver
Flaviviruses are among the most diverse viruses with over 85 species recognized. Taxonomically, this genus is one of the 4 recognized genera within the family Flaviviridae. Most flaviviruses of human public health significance, for example, dengue, yellow fever and Zika viruses, are arthropod-borne (arboviruses) and have two evolutionarily and ecologically distinct transmission cycles: a sylvatic transmission cycle, where the virus circulates between zoonotic vertebrate reservoir and amplification hosts and arboreal mosquitoes; and an urban transmission cycle, where the virus circulates between humans and peridomestic Aedes spp...
December 6, 2016: Current Opinion in Virology
https://www.readbyqxmd.com/read/27927737/the-rock-inhibitor-fasudil-prevents-chronic-restraint-stress-induced-depressive-like-behaviors-and-dendritic-spine-loss-in-rat-hippocampus
#17
Gonzalo García-Rojo, Cristóbal Fresno, Natalia Vilches, Gabriela Díaz-Véliz, Sergio Mora, Felipe Aguayo, Aníbal Pacheco, Nicolás Parra-Fiedler, Claudio S Parra, Paulina S Rojas, Macarena Tejos, Esteban Aliaga, Jenny L Fiedler
BACKGROUND: Dendritic arbor simplification and dendritic spine loss in the hippocampus -a limbic structure implicated in mood disorders- are assumed to contribute to symptoms of depression. These morphological changes imply changes in dendritic cytoskeleton. Rho GTPases are regulators of actin dynamics through their effector Rho kinase (ROCK). We have reported that chronic stress promotes depressive-like behaviors in rats, along with dendritic spine loss in apical dendrites of hippocampal pyramidal neurons; changes associated with ROCK activation...
December 7, 2016: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/27909399/a-subset-of-autism-associated-genes-regulate-the-structural-stability-of-neurons
#18
REVIEW
Yu-Chih Lin, Jeannine A Frei, Michaela B C Kilander, Wenjuan Shen, Gene J Blatt
Autism spectrum disorder (ASD) comprises a range of neurological conditions that affect individuals' ability to communicate and interact with others. People with ASD often exhibit marked qualitative difficulties in social interaction, communication, and behavior. Alterations in neurite arborization and dendritic spine morphology, including size, shape, and number, are hallmarks of almost all neurological conditions, including ASD. As experimental evidence emerges in recent years, it becomes clear that although there is broad heterogeneity of identified autism risk genes, many of them converge into similar cellular pathways, including those regulating neurite outgrowth, synapse formation and spine stability, and synaptic plasticity...
2016: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/27902687/limb-bone-structural-proportions-and-locomotor-behavior-in-a-l-288-1-lucy
#19
Christopher B Ruff, M Loring Burgess, Richard A Ketcham, John Kappelman
While there is broad agreement that early hominins practiced some form of terrestrial bipedality, there is also evidence that arboreal behavior remained a part of the locomotor repertoire in some taxa, and that bipedal locomotion may not have been identical to that of modern humans. It has been difficult to evaluate such evidence, however, because of the possibility that early hominins retained primitive traits (such as relatively long upper limbs) of little contemporaneous adaptive significance. Here we examine bone structural properties of the femur and humerus in the Australopithecus afarensis A...
2016: PloS One
https://www.readbyqxmd.com/read/27878209/preclinical-models-of-overwhelming-sepsis-implicate-the-neural-system-that-encodes-contextual-fear-memory
#20
Patricio T Huerta, Sergio Robbiati, Tomás Salvador Huerta, Anchal Sabharwal, Rose A Berlin, Maya Frankfurt, Bruce T Volpe
Long-term sepsis survivors sustain cryptic brain injury that leads to cognitive impairment, emotional imbalance, and increased disability burden. Suitable animal models of sepsis, such as cecal ligation and puncture (CLP), have permitted the analysis of abnormal brain circuits that underlie post-septic behavioral phenotypes. For instance, we have previously shown that CLP-exposed mice exhibit impaired spatial memory together with depleted dendritic arbors and decreased spines in the apical dendrites of pyramidal neurons in the CA1 region of the hippocampus...
November 17, 2016: Molecular Medicine
keyword
keyword
74451
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"