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https://www.readbyqxmd.com/read/29772585/thoracoplasty-current-view-on-indication-and-technique
#1
Oleg Kuhtin, Marina Veith, Mohammed Alghanem, Ivan Martel, Dmitrii Giller, Viktor Haas, Ludwig Lampl
Thoracoplasty was invented for removing cavities between thoracic wall and remnant lung or mediastinum. It was initially used in cases of tuberculosis or unspecific infections, while currently it is used mainly for space problems after lobectomy/pneumonectomy.This article presents an overview of the historical and current techniques of this surgical procedure.Nowadays, thoracoplasty is rarely performed due to the low incidence of diseases for which this method is necessary. Therefore, this method has even been discredited...
May 17, 2018: Thoracic and Cardiovascular Surgeon
https://www.readbyqxmd.com/read/29770265/herniation-of-packing-material-into-a-bronchopleural-fistula-after-right-pneumonectomy-and-clagett-window
#2
Iclal Ocak, Gideon Bollino, Diane Strollo
Diagnosis of a bronchopleural fistula (BPF) can be challenging in patients after pneumonectomy and Clagett window. Herein, we present a case of pneumonectomy for advanced lung cancer complicated by a BPF. Herniation of packing material from the open-chest cavity into the fistula and airways on computed tomography was an important clue to making the diagnosis.
2018: Journal of Clinical Imaging Science
https://www.readbyqxmd.com/read/29768335/igg4-related-disease-of-pulmonary-artery-causing-pulmonary-hypertension
#3
Hui Deng, Sheng Zhao, Yunlong Yue, Yong Liu, Yali Xu, Jin Qian, Xiaorong Ma, Peiliang Gao, Xiaoyan Yao, Xin Jiang, Xiqi Xu, Zhicheng Jing, Yong Wang, Lei Pan, Xinying Xue
IgG4-related disease (IgG4-RD) is recognized as an immune-mediated condition with pathology features of lymphoplasmacytic infiltrate, storiform fibrosis, and obliterative phlebitis, accompanied with or without elevated serum IgG4 concentrations. However, few of pulmonary artery IgG4-RD causing pulmonary hypertension (PH) was reported.The medical records of 3 patients with pulmonary artery IgG4-RD inducing PH were analyzed retrospectively.Imaging findings demonstrated that the lesions of 3 patients located in pulmonary artery, which were initially diagnosed as pulmonary thrombus or malignant tumor...
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29755103/-when-should-we-perform-surgery-for-n2-lung-cancer-induction-chemoradiotherapy-or-surgery-for-local-recurrence-or-residual-tumor-after-definitive-chemoradiotherapy
#4
Hiroyuki Ito, Haruhiko Nakayama
BACKGROUND: Standard treatment for locally advanced clinical N2 lung cancer is definitive chemoradiotherapy, and induction chemoradiotherapy(IND-CRT) followed by surgery is an option. Most of them recurs remotely within a few years after initial therapy. Patients who received salvage surgery(SAL) after definitive chemoradiotherapy had no remote relapse for some period after definitive chemoradiotherapy, thus the outcome of SAL may be better than those of IND-CRT, but the operative risks of both procedures seem to be high...
April 2018: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/29755101/-outcome-of-surgical-treatment-of-locally-advanced-lung-cancer-after-induction-chemoradiotherapy
#5
Masayuki Tanahashi, Haruhiro Yukiue, Eriko Suzuki, Naoko Yoshii, Shinsuke Kitazawa, Yasunori Kaminuma, Hiroshi Niwa
OBJECTIVE: The outcome of surgical treatment of non-small-cell lung cancer after induction chemoradiotherapy was investigated. SUBJECTS: The subjects were 74 patients with non-small-cell lung cancer who received induction chemoradiotherapy( ICRT) between 1998 and 2016. ICRT was administered to pT3 lung cancer invading the chest wall(20 patients), pT4 lung cancer invading the adjacent organ(22 patients), and cN2 lung cancer(32 patients). cN2 was confirmed by mediastinoscopy(13 patients) and endobronchial ultrasound-guided transbronchial needle aspiration(EBUS-TBNA)(19 patients)...
April 2018: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/29753120/a-phase-i-trial-of-surgical-resection-and-intraoperative-hyperthermic-cisplatin-and-gemcitabine-for-pleural-mesothelioma
#6
Bryan M Burt, William G Richards, Hyun-Sung Lee, Sylvia Bartel, Marcelo C Dasilva, Ritu R Gill, Michael T Jaklitsch, Bruce E Johnson, Scott J Swanson, Raphael Bueno, David J Sugarbaker
INTRODUCTION: The primary objective of this single-institution Phase I clinical trial was to establish the maximum tolerated dose (MTD) of gemcitabine added to cisplatin delivered as heated intraoperative chemotherapy (HIOC) following resection of malignant pleural mesothelioma (MPM). METHODS: Extrapleural pneumonectomy (EPP) and pleurectomy/decortication (P/D) treatment arms were based on investigators' assessment of patient fitness and potential for macroscopic complete resection...
May 9, 2018: Journal of Thoracic Oncology
https://www.readbyqxmd.com/read/29752282/niche-mediated-bmp-smad-signaling-regulates-lung-alveolar-stem-cell-proliferation-and-differentiation
#7
Mei-I Chung, Melissa Bujnis, Christina E Barkauskas, Yoshihiko Kobayashi, Brigid L M Hogan
The bone morphogenetic protein (BMP) signaling pathway, including antagonists, functions in lung development and regeneration of tracheal epithelium from basal stem cells. Here, we explore its role in the alveolar region, where type 2 epithelial cells (AT2s) and Pdgfrα+ type 2-associated stromal cells (TASCs) are components of the stem cell niche. We use organoids and in vivo alveolar regrowth after pneumonectomy (PNX) - a process that requires proliferation of AT2s and differentiation into type 1 cells (AT1s)...
May 11, 2018: Development
https://www.readbyqxmd.com/read/29750933/regional-thoracic-surgery-quality-collaboration-formation-providence-thoracic-surgery-initiative
#8
John R Handy, Kimberly Costas, Robert McKenna, Steven Nisco, Raymond Schaerf, Kenton Stephens, Eric Vallières, Kasia Konieczny, Roshanthi Weerasinghe, Mansen Wang, Katherine Lothrop, Cathy Betzer
BACKGROUND: Surgery quality initiatives improve clinical outcomes in cardiac and general surgery. No mature thoracic surgery (TS) regional effort has been described. METHODS: An intramural grant funded the Thoracic Surgery Initiative (TSI). Using professional organization, site specific administrative and clinical databases, surgeons performing TS across a large western health system were identified. Participants were recruited through stakeholder surveys, personal contact and meetings...
May 8, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29748018/facility-volume-and-postoperative-outcomes-for-malignant-pleural-mesothelioma-a-national-cancer-data-base-analysis
#9
Vivek Verma, Christopher A Ahern, Christopher G Berlind, William D Lindsay, Surbhi Grover, Melissa J Culligan, Joseph S Friedberg, Charles B Simone
PURPOSE: This study of a large, contemporary national database evaluated postoperative outcomes and overall survival (OS) for malignant pleural mesothelioma (MPM) by facility volume. METHODS: The National Cancer Database was queried for newly-diagnosed non-metastatic MPM undergoing definitive surgery (extrapleural pneumonectomy (EPP) or pleurectomy/decortication (P/D)). Patients were dichotomized into those receiving therapy at a high-volume facility (HVF), defined a priori at the 90th percentile of case volume, with all others categorized as lower-volume facilities (LVFs)...
June 2018: Lung Cancer: Journal of the International Association for the Study of Lung Cancer
https://www.readbyqxmd.com/read/29744048/icg-easily-detects-not-only-the-segmental-plane-but-also-the-course-and-blood-distribution-of-the-bronchial-artery-case-report
#10
Hidetaka Uramoto, Nozomu Motono
Introduction: Sublobar resection has become an acceptable alternative to lobectomy in patients with early-stage lung cancer. Most notable among these approaches is indocyanine green fluorescence (ICG) imaging. Case presentation: Operative finding showed clear green staining of the left upper lobe, S6, superior pulmonary vein, and inferior PV under fluorescence navigation. Soon, the bronchial artery of right lower bronchus showed clear green staining. Next, the whole right lower bronchus is deeply colored green...
April 2018: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/29737212/baicalein-ameliorates-pulmonary-arterial-hypertension-caused-by-monocrotaline-through-downregulation-of-et-1-and-et-a-r-in-pneumonectomized-rats
#11
Wen-Lin Hsu, Yu-Chieh Lin, Jing-Ren Jeng, Heng-Yuan Chang, Tz-Chong Chou
Baicalein (BE) extracted from Scutellaria baicalensis Georgi is able to alleviate various cardiovascular and inflammatory diseases. However, the effects of BE on pulmonary arterial hypertension (PAH) remain unknown. Therefore, the present study aimed to examine whether BE ameliorates pneumonectomy and monocrotaline-induced PAH in rats and further investigate the underlying molecular mechanisms. Administration of BE greatly attenuated the development of PAH as evidenced by an improvement of its characteristic features, including elevation of right ventricular systolic pressure, right ventricular hypertrophy, and pulmonary vascular remodeling...
May 8, 2018: American Journal of Chinese Medicine
https://www.readbyqxmd.com/read/29734831/ipsilateral-pulmonary-infarction-after-major-lung-resection
#12
Vasileios K Kouritas, Emmanuel M Kefaloyannis, Nilanjan Chaudhuri, Richard Milton
Background Lung infarction is a rare complication of lung resection, developing mainly because of technical errors. In some cases, a specific reason cannot be identified. This study aimed to investigate the occurrence, characteristics, and outcome of this pathology in a series of patients. Methods The medical records of patients who underwent reoperation for lung infarction without an apparent cause (based on imaging, reoperation findings, and histopathology) after major lung resection at our institution from 2006 to 2015, were investigated...
January 1, 2018: Asian Cardiovascular & Thoracic Annals
https://www.readbyqxmd.com/read/29730353/aggressive-surgical-resection-of-pulmonary-artery-intimal-sarcoma
#13
Yoko Yamamoto, Yasushi Shintani, Soichiro Funaki, Masaki Taira, Takayoshi Ueno, Tomohiro Kawamura, Ryu Kanzaki, Masato Minami, Yoshiki Sawa, Meinoshin Okumura
Intimal sarcoma of the pulmonary artery is a rare and highly malignant neoplasm. We herein report a case of a 30-year-old woman with an extensive right pulmonary artery tumor who underwent an emergent operation. The tumor was aggressively resected with right pneumonectomy and reconstruction of the right ventricle outflow tract and left pulmonary artery. Although the resected margin at the left pulmonary artery was positive, as confirmed by Mouse double minute type 2 homolog staining, she is doing well and remains free of relapse at 16 months after the operation...
May 3, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29730119/surgical-management-of-bronchial-stumps-in-lobar-lung-transplantation
#14
Hidenao Kayawake, Toyofumi F Chen-Yoshikawa, Akihiro Aoyama, Hideki Motoyama, Masatsugu Hamaji, Kyoko Hijiya, Hiroshi Date
BACKGROUND: The validity of lobar lung transplantation (LT) has been established in both living-donor lobar lung transplantation (LDLLT) and cadaveric-donor lung transplantation (CLT). However, bronchial stump management in lobar LT has not been precisely documented. Thus, we retrospectively analyzed our strategies for bronchial stump management in lobar LT. METHODS: Between June 2008 and August 2016, 145 LTs (72 LDLLTs and 73 CLTs) were performed at our institution...
April 7, 2018: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29723532/the-persistent-problem-of-local-regional-failure-following-surgery-for-early-stage-lung-cancer
#15
Gregory D Judy, Orit Kaidar-Person, Allison Deal, Yue Wang, Andrew Migliardi, Jason Long, Benjamin Haithcock, Lawrence B Marks
BACKGROUND: The goal of the present study is to estimate the rate of local/regional failure (LRF) following definitive surgery for early stage non-small cell lung cancer (NSCLC) (without postoperative radiation) in the era of contemporary imaging and minimally invasive surgical techniques. METHODS: Retrospectively reviewed medical records of patients with early-stage NSCLC (pathologic T1-4, N0-1) who underwent lobectomy, sleeve lobectomy, bilobectomy, or pneumonectomy with/without adjuvant chemotherapy between 2007 and 2015...
April 30, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29715708/the-feasibility-of-thoracoscopic-left-pneumonectomy
#16
Hao Xu, Linyou Zhang
OBJECTIVE:  In this study, we describe our experience with video-assisted thoracoscopic surgery (VATS) left pneumonectomy as a treatment for advanced malignant and benign diseases. METHODS:  Patients who underwent VATS left pneumonectomy in our clinic between October 2013 and August 2017 were retrospectively evaluated. VATS pneumonectomy was successfully completed in 46 patients. We reviewed and analyzed the characteristics of the patients in addition to intraoperative parameters, chest tube duration, length of hospital stay, morbidity, and mortality...
May 1, 2018: Thoracic and Cardiovascular Surgeon
https://www.readbyqxmd.com/read/29707366/sleeve-lobectomy-for-lung-adenocarcinoma-treated-with-neoadjuvant-afatinib
#17
Ichiro Sakanoue, Hiroshi Hamakawa, Reiko Kaji, Yukihiro Imai, Nobuyuki Katakami, Yutaka Takahashi
Afatinib, the second-generation epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI), has been postulated to be associated with improved inhibition of EGFR-dependent tumor growth compared with first-generation EGFR-TKIs for advanced non-small cell lung cancer (NSCLC). We present a case of lung adenocarcinoma (cT3N0M0) treated with neoadjuvant afatinib and sleeve lobectomy. Because of the location of the tumor, reduced FEV1 value, and the presence of EGFR mutation, the patient was planned to be prescribed afatinib (30 mg daily) for 3 weeks as neoadjuvant therapy and underwent sleeve lobectomy to avoid pneumonectomy as much as possible...
March 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29701375/surgical-treatment-for-elderly-patients-with-lung-cancer
#18
Telma Calado, Mariana Antunes, Daniel Cabral, Magda Alvoeiro, Francisco Félix
INTRODUCTION: Non-small cell lung cancer is a very common disease in the elderly population and its incidence in this particular population is expected to increase further, because of the ageing of the Western population. Pulmonary resection is often not recommended in the elderly, even though they have no medical contraindications to surgery. Such patients are postulated to have a limited life expectancy, the rate of complications and perioperative death is considered to be higher than younger population...
July 2017: Revista Portuguesa de Cirurgia Cardio-torácica e Vascular
https://www.readbyqxmd.com/read/29701367/severe-intraoperative-complications-during-vats-anatomical-ressections-and-their-surgical-resolution-in-a-portuguese-thoracic-surgery-centre-a-9-year-review
#19
João Eurico Reis, Ana Rita Costa, Manuel Godinho, João Santos Silva, Rita Barata, Ivan Bravio, Fernando Martelo, Paulo Calvinho, José Fragata
INTRODUCTION: Many studies have demonstrated that video-assisted thoracoscopic surgery (VATS) is not only feasible and safe but is actually the approach chosen for an increasing number of pulmonary anatomic resections. There are however few studies reporting on severe intraoperative complications during VATS anatomical ressections and their resolution. OBJECTIVE: Our aim is to analyse the incidence of severe intraoperative complications during VATS anatomical ressections, at our department, in the past nine years, and describe their technical resolution during the surgery...
July 2017: Revista Portuguesa de Cirurgia Cardio-torácica e Vascular
https://www.readbyqxmd.com/read/29697836/aortobronchial-fistula-caused-by-an-endobronchial-lobar-y-stent-a-word-of-caution
#20
Margarete Härting, Stefan Welter, Clemens Aigner
A 17-year-old female patient with a history of pulmonary tuberculosis was admitted with progressive dyspnoea and haemoptysis. Five months prior to admission, a left bronchial carina Y stent was implanted. Because of the already destroyed parenchyma, a pneumonectomy was planned. Intraoperatively, an aortobronchial fistula was discovered as the source of bleeding, which could be stopped by pledget-armed sutures. The formation of an aortobronchial fistula has to be considered as a potential source of endobronchial bleeding after stent implantation...
April 25, 2018: Interactive Cardiovascular and Thoracic Surgery
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