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https://www.readbyqxmd.com/read/29906542/expression-of-neu5ac%C3%AE-2-3gal-and-neu5ac%C3%AE-2-6gal-on-the-nasal-mucosa-of-patients-with-chronic-rhinosinusitis-and-its-possible-effect-on-bacterial-biofilm-formation
#1
Qinying Wang, Haihong Chen, Yang Yang, Bo Wang
OBJECTIVE: Adherence of pathogen to nasal mucosa and colonization is the first step of bacterial biofilm(BBF) formation in patients with chronic rhinosinusitis (CRS).Terminal sialic acids presenting on cell surface are potential targets for bacterial binding, thus may partly contribute to the pathogenesis of CRS. However, little has been published in this respect, the purpose of our study aimed to investigate the expression of sialic acids on the nasal mucosa in CRS patients and its possible effect on BBF formation...
June 12, 2018: Microbial Pathogenesis
https://www.readbyqxmd.com/read/29904490/rectal-lipoma-as-a-lead-point-for-colo-colonic-intussusception
#2
Farzaneh Shobeirian, Mersad Mehrnahad, Hossein Soleimantabar
Intussusception in adults is a rare condition and most of the time there is a pathologic lesion that serves as a leading point. Unless highly suspicious, intussusception causing chronic abdominal pain and obstructive symptoms are rarely diagnosed before the surgery. In this study, we report a colo-colonic intussusception in a 73-year-old man with an intraluminal rectal lipoma as the leading point.
April 2018: Radiology Case Reports
https://www.readbyqxmd.com/read/29902524/surgical-protocol-and-outcome-for-sigmoidovesical-fistula-secondary-to-diverticular-disease-of-the-left-colon-a-retrospective-cohort-study
#3
Hany M El-Haddad, Mohamed I Kassem, Ahmed A Sabry, Ahmed Abouelfotouh
BACKGROUND: Diverticular disease of sigmoid colon can rarely be complicated by a connective track to urinary bladder. Pneumaturia and fecaluria are the pathognomonic symptoms. Resection surgery is the preferred treatment to overcome the renal sequellae of the disease. The purpose of this study is to propose a guiding classification to help general surgeons during surgical management of diverticular disease complicated by sigmoidovesical fistula (SVF). PATIENTS AND METHODS: The data of 40 cases with colovesical fistula due to diverticular disease of sigmoid colon were retrospectively analyzed...
June 11, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29901613/a-rare-case-of-primary-small-bowel-de-differentiated-liposarcoma-causing-intussusception-a-case-report
#4
Kentaro Matsuo, Masaya Inoue, Yasutsugu Shirai, Tatsuki Kataoka, Shuji Kagota, Kohei Taniguchi, Sang-Woong Lee, Kazuhisa Uchiyama
RATIONALE: Liposarcoma (LPS) is a relatively rare malignant soft tissue tumor. Management of LPS including diagnosis is difficult, because it has no characteristic symptoms and no established effective treatment. Herein we reported an extremely rare case of intussusception induced by primary small bowel LPS. PATIENT'S CONCERN: A-84-year-old male was a consult to our Emergency Department with symptoms of a terrible general fatigue, abdominal pain, and vomiting. DIAGNOSIS: Abdominal ultrasonography and computed tomography (CT) revealed probable intussusception...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29899765/anal-extrusion-of-ventriculoperitoneal-shunt-a-report-of-two-cases-and-review-of-literature
#5
REVIEW
Abul Hasan, Somnath Sharma, Sanjeev Chopra, Devendra Kumar Purohit
We report two cases of gastrointestinal perforation by ventriculoperitoneal (VP) shunts and review the literature on the topic. The time interval between shunt surgery and detection of bowel perforation is minimum in infants and increases with age. Sigmoid and transverse colon followed by stomach are the most frequent sites of gastrointestinal perforations by VP shunts.
January 2018: Journal of Pediatric Neurosciences
https://www.readbyqxmd.com/read/29898664/an-unusual-diverticulum-adjacent-to-two-large-colonic-polyps-a-case-report
#6
John Schembri, Jonathan Bury, Lesley Hunt, Stuart Riley
BACKGROUND: Adenocarcinomas can arise in a variety of circumstances in which intestinal segments have been used for urinary diversions. Whereas ureterosigmoidostomy is the oldest and simplest form of continent urinary diversion it also seems to be the most dangerous in this regard. Herein we present a case of colonic neoplasia complicating a non-functioning ureterosigmoidostomy after 55 years; the longest latent period documented to date. CASE PRESENTATION: A 56-year-old lady born with congenital bladder exystrophy and who had a functional ileal conduit presented to us with a 6 month history of change in bowel habit and rectal bleeding...
June 14, 2018: BMC Gastroenterology
https://www.readbyqxmd.com/read/29895094/oncological-outcomes-of-complete-versus-conventional-mesocolic-excision-in-laparoscopic-right-hemicolectomy
#7
Min Sung An, HyungJoo Baik, Se Hui Oh, Yo-Han Park, Sang Hyuk Seo, Kwang Hee Kim, Kwan Hee Hong, Ki Beom Bae
BACKGROUND: Complete mesocolic excision (CME) has been proposed for colon cancer to improve oncological outcomes. The risks and benefits of laparoscopic CME have not been examined fully. We compared short- and long-term outcomes of CME with a conventional mesocolic excision (non-CME) in laparoscopic right hemicolectomy (RHC) for right-sided colon cancer. METHODS: In total, 115 patients who underwent laparoscopic RHC with stage I-III right-sided colon cancer at Busan Paik Hospital from August 2007 to October 2011 were enrolled in this case-control study...
June 12, 2018: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/29894583/prognostic-value-and-characteristics-of-n1c-colorectal-cancer
#8
Morgane Bouquot, Ben Creavin, Nicolas Goasguen, Najim Chafai, Emmanuel Tiret, Thierry André, Jean-Francois Flejou, Yann Parc, Jérémie H Lefevre, Magali Svrcek
The presence of tumor deposits (TD) in colorectal cancer (CRC) is associated with poor prognosis. The 7th edition of TNM subclassified a new nodal stage, N1c, characterized by the presence of TD without any concurrent positive lymph node (LN). It is not clear if the N1c category is equal or not to LN metastasis. We aimed to examine the prevalence, characteristics and prognostic significance of this new subcategory METHODS: Consecutive patients who underwent surgery for CRC in two centers (2011-2014) were analyzed...
June 12, 2018: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/29893319/the-value-of-serum-survivin-level-in-early-diagnosis-of-cancer
#9
Meral Gunaldi, Nilgun Isiksacan, Hakan Kocoglu, Yildiz Okuturlar, Omur Gunaldi, Turkan Ozturk Topcu, Mehmet Karabulut
Objective: Survivin is one of the apoptosis inhibitor proteins, and it plays a key role in tumor angiogenesis and cancer progression. This study was conducted to investigate the serum level of survivin to determine its diagnostic value in cancer patients. Materials and Methods: Blood samples were taken from cancer patients (n = 67) prior to surgery or chemo/radiotherapy and age-matched healthy volunteers (n = 23). The serum levels of survivin were analyzed by enzyme-linked immunosorbent assays...
April 2018: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/29891525/weekend-effect-in-emergency-colon-and-rectal-cancer-surgery-a-prospective-study-using-data-from-the-dutch-colorectal-audit
#10
Daniëlle D Huijts, Julia T van Groningen, Onno R Guicherit, Jan Willem T Dekker, Leti van Bodegom-Vos, Esther Bastiaannet, Johannes A Govaert, Michel W Wouters, Perla J Marang-van de Mheen
Background: It is unclear whether emergency weekend colon and rectal cancer surgery are associated with worse outcomes (ie, weekend effect) because previous studies mostly used administrative data, which may insufficiently adjust for case-mix. Materials and Methods: Prospectively collected data from the 2012-2015 Dutch ColoRectal Audit (n=5,224) was used to examine differences in 30-day mortality and severe complication and failure-to-rescue rates for emergency weekend (Saturday and Sunday) versus Monday surgery, stratified for colon and rectal cancer...
June 2018: Journal of the National Comprehensive Cancer Network: JNCCN
https://www.readbyqxmd.com/read/29890817/nonshaved-ear-surgery-effect-of-hair-on-surgical-site-infection-of-the-middle-ear-mastoid-surgery-and-patients-preference-for-the-hair-removal
#11
Dong-Hee Lee, Soonil Yoo, Eunhye Shin, Yesun Cho
Background and Objectives: This study aimed 1) to compare the rates of surgical site infection (SSI) between two groups with and without preoperative hair shaving, 2) to compare the bacterial colonization just before the skin incision between them, and 3) to evaluate people's preference for the hair shaving. Subjects and Methods: The retrospective study enrolled cases in which middle ear and mastoid surgery was performed with as well as without hair removal. Main measurement outcomes were the SSI rate within 3 months following the surgery, bacterial culture results obtained from the incision area just before the skin incision, and questionnaire to evaluate the preference for hair shaving from patients with chronic suppurative otitis media but without experience with the ear surgery...
June 14, 2018: Journal of Audiology & Otology
https://www.readbyqxmd.com/read/29890349/healing-after-resection-of-colonic-endometriosis-and-growth-factor-enriched-agents-an-experimental-rat-model
#12
Anastasia Prodromidou, Kitty Pavlakis, Vasileios Pergialiotis, Maximos Frountzas, Nikolaos Machairas, Ioannis D Kostakis, Laskarina M Korou, Konstantinos Stergios, Dimitrios Dimitroulis, George Vaos, Despoina N Perrea
STUDY OBJECTIVE: To examine the potential beneficial effect of platelet rich plasma (PRP) and fibrin sealant (TISSEEL; Baxter Healthcare Corporation, Deerfield, IL) on bowel wound healing after shaving of an experimentally induced endometriotic lesion. DESIGN: Single-blind, randomized study (Canadian Task Force classification I). SETTING: Certified animal research facility. ANIMALS: Thirty female Sprague-Dawley rats...
June 8, 2018: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29888718/surgical-management-of-anorectal-foreign-bodies
#13
H Cinar, M Berkesoglu, M Derebey, E Karadeniz, C Yildirim, K Karabulut, T Kesicioglu, K Erzurumlu
Purpose: Anorectal foreign bodies (AFBs) inserted into anus constitute one of the most important problems needing surgical emergency due to its complications. We describe our experience in the diagnosis and treatment of AFBs retained in the rectosigmoid colon. Materials and Methods: Between the years 2006 and 2015, a total of 11 patients diagnosed with AFBs were admitted to an emergency room and general surgery clinics. They were diagnosed and treated in four different hospitals in four different cities in Turkey...
June 2018: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29888630/a-critical-appraisal-of-advances-in-the-diagnosis-of-diverticular-disease
#14
Antonio Tursi
Diverticulosis of the colon is a common condition, and about one fourth of those people develop symptoms, which is called "diverticular disease" (DD). Since there are still some concerns about the diagnosis of diverticular disease, the aim of this review was to analyse current and evolving advances in its diagnosis. Area covered: Analysis of clinical, radiology, laboratory and endoscopic tools to pose a correct diagnosis of DD was performed according to current PubMed literature. Expert commentary: A combination of clinical characteristic of the abdominal pain and fecal calprotectin expression may help to differentiate between Symptomatic Uncomplicated Diverticular Disease (SUDD) and Irritable Bowel Syndrome (IBS)...
June 9, 2018: Expert Review of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29888518/epidemiology-and-outcomes-of-pretransplant-methicillin-resistant-staphylococcus-aureus-screening-in-pediatric-solid-organ-transplant-candidates
#15
Grant Paulsen, Samantha Blum, Lara Danziger-Isakov
MRSA infection following SOT is an important cause of morbidity and mortality, but epidemiology and risk factors for colonization prior to pediatric SOT remain unclear. A retrospective cohort of SOT patients ≤21 years of age from 2009 to 2014 was evaluated. Demographics, MRSA screens, timing of transplantation, and MRSA infection were abstracted. From 2013 to 2014, 130 SOT candidates were screened or had known prior MRSA infection. Seventeen patients (13%) were MRSA colonized. Liver transplant candidates were least likely to be colonized (OR 0...
June 11, 2018: Pediatric Transplantation
https://www.readbyqxmd.com/read/29885983/evidence-based-quality-standards-improve-prognosis-in-colon-cancer-care
#16
Freya Trautmann, Christoph Reißfelder, Mathieu Pecqueux, Jürgen Weitz, Jochen Schmitt
BACKGROUND: Colon cancer requires interdisciplinary care with quality of initial surgical treatment being a major prognostic factor. Implementation of quality standards based on structural and procedural indicators in routine care via certification (Germany) or accreditation (USA) is an established quality assurance method. However, evidence on effects is scarce. We undertook a population-based cohort study to investigate the effectiveness of colon cancer care in certified vs non-certified hospitals...
May 17, 2018: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29884570/colorectal-cancer-survival-at-an-oncologic-center-in-colombia-a-historic-cohort-study
#17
S M Campo-Sánchez, J Camargo-Trillos, J A Calle-Ramírez, L R Gómez-Wolff, L A Sánchez-Patiño, H I García-García
INTRODUCTION AND AIMS: In Colombia, cancer of the colon is the third most frequent cancer in relation to incidence and mortality. Five-year survival depends on stage at diagnosis, albeit that rate is not known for the country. The aim of the present study was to characterize the overall survival and disease-free survival rates in an adult population with colorectal cancer treated at an oncology center in Medellín, Colombia. MATERIALS AND METHODS: A retrospective cohort study was conducted...
June 5, 2018: Revista de Gastroenterología de México
https://www.readbyqxmd.com/read/29882252/the-impact-of-ileal-pouch-anal-anastomosis-on-graft-survival-following-liver-transplantation-for-primary-sclerosing-cholangitis
#18
P J Trivedi, J Reece, R W Laing, E Slaney, R Cooney, B K Gunson, S K Kamarajah, T Pinkney, F Thompson, P Muiesan, A Schlegel, G M Hirschfield, T Iqbal, J Ferguson
BACKGROUND: Liver transplantation is the only life-extending intervention for primary sclerosing cholangitis (PSC). Given the co-existence with colitis, patients may also require colectomy; a factor potentially conferring improved post-transplant outcomes. AIM: To determine the impact of restorative surgery via ileal pouch-anal anastomosis (IPAA) vs retaining an end ileostomy on liver-related outcomes post-transplantation. METHODS: Graft survival was evaluated across a prospectively accrued transplant database, stratified according to colectomy status and type...
June 8, 2018: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/29881759/predicting-future-elective-colon-resection-for-diverticulitis-using-patterns-of-health-care-utilization
#19
Lucas W Thornblade, David R Flum, Abraham D Flaxman
Background: Recurrent diverticulitis is the most common reason for elective colon surgery and, although professional societies now recommend against early resection, its use continues to rise. Shared decision making decreases use of low-value surgery but identifying which patients are most likely to elect surgery has proven difficult. We hypothesized that Machine Learning algorithms using health care utilization (HCU) data can predict future clinical events including early resection for diverticulitis...
January 24, 2018: EGEMS
https://www.readbyqxmd.com/read/29879760/preclinical-efficacy-of-v4q5-ddavp-a-second-generation-vasopressin-analog-on-metastatic-spread-and-tumor-associated-angiogenesis-in-colorectal-cancer
#20
Juan Garona, Natasha T Sobol, Marina Pifano, Valeria I Segatori, Daniel E Gomez, Giselle V Ripoll, Daniel F Alonso
Purpose: Control of metastatic spread of colorectal cancer (CRC) remains as a major therapeutic challenge. [V4Q5]dDAVP is a vasopressin peptide analog with previously reported anticancer activity against carcinoma tumors. By acting as a selective agonist of AVPR2 present in endothelial and tumor cells, [V4Q5]dDAVP is able to impair tumor aggressiveness and distant spread. Our aim was to evaluate the potential therapeutic benefits of [V4Q5]dDAVP on highly aggressive CRC disease using experimental models with translational relevance...
June 1, 2018: Cancer Research and Treatment: Official Journal of Korean Cancer Association
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