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https://www.readbyqxmd.com/read/27911587/effects-of-variable-pressure-support-ventilation-on-regional-homogeneity-and-aeration
#1
Tommaso Mauri, Marta Lazzeri, Alfio Bronco, Giacomo Bellani, Antonio Pesenti
No abstract text is available yet for this article.
December 2, 2016: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/27906709/looking-closer-at-acute-respiratory-distress-syndrome-the-role-of-advanced-imaging-techniques
#2
Giacomo Bellani, Jean-Jaques Rouby, Jean-Michel Constantin, Antonio Pesenti
PURPOSE OF REVIEW: Advanced imaging techniques have provided invaluable insights in understanding of acute respiratory distress syndrome (ARDS) and the effect of therapeutic strategies, thanks to the possibility of gaining regional information and moving from simple 'anatomical' information to in-vivo functional imaging. RECENT FINDINGS: Computed tomography (CT) led to the understanding of several ARDS mechanisms and interaction with mechanical ventilation. It is nowadays frequently part of routine diagnostic workup, often leading to treatment changes...
November 30, 2016: Current Opinion in Critical Care
https://www.readbyqxmd.com/read/27871970/surgical-management-of-post-traumatic-atlantoaxial-rotatory-fixation-due-to-c2-facet-fracture-5-clinical-cases
#3
H Peyriere, T Graillon, S Pesenti, P Tropiano, B Blondel, S Fuentes
PURPOSE: Report the results of surgical treatment of post-traumatic atlantoaxial rotatory fixation (AARF) due to C2 articular facet fracture in adults. MATERIAL AND METHODS: The records of five patients treated since 2009 for AARF due to a C2 articular facet fracture were analyzed retrospectively. Three women and two men with an average age of 60 years (27-82) were included, one of whom initially had neurological deficits. In all cases, the surgical strategy consisted of posterior fixation: Harms-type in four cases and trans-articular with hooks in one case...
November 18, 2016: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/27865518/impact-of-surgical-correction-of-a-u-shaped-sacral-fracture-on-sagittal-spino-pelvic-alignment-regarding-one-case
#4
N Mansouri, T Graillon, K Farah, S Pesenti, B Blondel, S Fuentes
U-shaped sacral fractures are uncommon and are mostly the consequence of a high-energy kinetic trauma. The sacrum is a crucial element for sagittal alignment in a standing position as it determines the value of the pelvic incidence, which is a fixed and unchanging parameter for a given individual. We report the case of a 21-year-old man who underwent corrective surgery for a type II U-shaped fracture of the sacrum (according to the Roy-Camille classification), associated with a S1-S2 dislocation and sacral kyphosis that modified the patient's pelvic incidence...
December 2016: Neuro-Chirurgie
https://www.readbyqxmd.com/read/27864924/pentraxin-3-in-patients-with-severe-sepsis-or-shock-the-albios-trial
#5
Pietro Caironi, Serge Masson, Tommaso Mauri, Barbara Bottazzi, Roberto Leone, Michela Magnoli, Simona Barlera, Filippo Mamprin, Andrea Fedele, Alberto Mantovani, Gianni Tognoni, Antonio Pesenti, Luciano Gattinoni, Roberto Latini
BACKGROUND: The long pentraxin PTX3 is a key component of the humoral arm of innate immunity related to sepsis severity and mortality. We evaluated the clinical and prognostic significance of circulating PTX3 in the largest cohort ever reported of patients with severe sepsis or septic shock. DESIGN: Plasma PTX3 was measured on days 1, 2 and 7 after randomization of 958 patients to albumin or crystalloids for fluid resuscitation in the multicenter Albumin Italian Outcome Sepsis (ALBIOS) trial...
November 16, 2016: European Journal of Clinical Investigation
https://www.readbyqxmd.com/read/27826904/forearm-lengthening-management-of-elbow-and-wrist
#6
REVIEW
Franck Launay, Sébastien Pesenti
The risk and consequences of an elbow or a wrist contracture are lower during a forearm lengthening than during a lower limb lengthening. This kind of complication can mostly be avoided by an active and intensive regimen of physiotherapy. However, there are some challenges to deal with in treating the disorder multiple exostoses and the radial club hand, including the lack of consensus on the best treatment for multiple exostoses. However, it is important to realize that the evolution of multiple exostoses can lead to a radial head dislocation which will damage the pronation and the supination range of motion...
November 8, 2016: Journal of Children's Orthopaedics
https://www.readbyqxmd.com/read/27826903/bone-lengthening-bridging-joints-soft-tissue-releases-physiotherapy
#7
REVIEW
Franck Launay, Sébastien Pesenti
When we lengthen a bone in a child, the parents and the family circle are often obsessed by the amount a lengthening obtained. However, for the surgeon, lengthen a bone is quite pretty easy, but dealing with the joints above and below the lengthening area can be very challenging. Indeed, during the lengthening process, muscles and tendons will be progressively stretched, leading to potential joint contracture or even dislocation. The objective of the surgeon will be to avoid this situation. The first mean at disposal is the physiotherapy in order to help the joints to be more supple and to maintain their range of motion...
November 8, 2016: Journal of Children's Orthopaedics
https://www.readbyqxmd.com/read/27782936/the-lateral-wedge-augmentation-trochleoplasty-in-a-pediatric-population-a-5-year-follow-up-study
#8
Sébastien Pesenti, Benjamin Blondel, Gregory Armaganian, Sébastien Parratte, Gérard Bollini, Franck Launay, Jean-Luc Jouve
Patellofemoral instability in children requires surgery when recurrent dislocation occurs. The aim of this study is to report the 5-year clinical and radiographic outcomes following lateral wedge augmentation trochleoplasty of the femoral trochlea. This is a review of 23 (mean age: 12.5 years) patients who underwent surgery for recurrent patellar dislocations related to a flat trochlea. In every case, a lateral wedge augmentation trochleoplasty was performed with preservation of the growth plate. This surgery was consistently associated with a soft tissue procedure...
October 25, 2016: Journal of Pediatric Orthopedics. Part B
https://www.readbyqxmd.com/read/27757516/potentially-modifiable-factors-contributing-to-outcome-from-acute-respiratory-distress-syndrome-the-lung-safe-study
#9
John G Laffey, Giacomo Bellani, Tài Pham, Eddy Fan, Fabiana Madotto, Ednan K Bajwa, Laurent Brochard, Kevin Clarkson, Andres Esteban, Luciano Gattinoni, Frank van Haren, Leo M Heunks, Kiyoyasu Kurahashi, Jon Henrik Laake, Anders Larsson, Daniel F McAuley, Lia McNamee, Nicolas Nin, Haibo Qiu, Marco Ranieri, Gordon D Rubenfeld, B Taylor Thompson, Hermann Wrigge, Arthur S Slutsky, Antonio Pesenti
PURPOSE: To improve the outcome of the acute respiratory distress syndrome (ARDS), one needs to identify potentially modifiable factors associated with mortality. METHODS: The large observational study to understand the global impact of severe acute respiratory failure (LUNG SAFE) was an international, multicenter, prospective cohort study of patients with severe respiratory failure, conducted in the winter of 2014 in a convenience sample of 459 ICUs from 50 countries across five continents...
October 18, 2016: Intensive Care Medicine
https://www.readbyqxmd.com/read/27753501/non-invasive-ventilation-of-patients-with-ards-insights-from-the-lung-safe-study
#10
Giacomo Bellani, John G Laffey, Tài Pham, Fabiana Madotto, Eddy Fan, Laurent Brochard, Andres Esteban, Luciano Gattinoni, Vesna Bumbasirevic, Lise Piquilloud, Frank van Haren, Anders Larsson, Daniel F McAuley, Philippe R Bauer, Yaseen M Arabi, Marco Ranieri, Massimo Antonelli, Gordon D Rubenfeld, B Taylor Thompson, Hermann Wrigge, Arthur S Slutsky, Antonio Pesenti
BACKGROUND: Non-invasive ventilation (NIV) is increasingly used in patients with Acute Respiratory Distress Syndrome (ARDS). Whether, during NIV, the categorization of ARDS severity based on the PaO2/FiO2 Berlin criteria is useful is unknown. The evidence supporting NIV use in patients with ARDS remains relatively sparse. METHODS: The Large observational study to UNderstand the Global impact of Severe Acute respiratory FailurE (LUNG SAFE) study described the management of patients with ARDS...
October 18, 2016: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/27688213/mucosal-perforation-during-laparoscopic-heller-myotomy-has-no-influence-on-final-treatment-outcome
#11
Renato Salvador, Lorenzo Spadotto, Giovanni Capovilla, Guerrino Voltarel, Elisa Pesenti, Cristina Longo, Francesco Cavallin, Loredana Nicoletti, Alberto Ruol, Michele Valmasoni, Stefano Merigliano, Mario Costantini
BACKGROUND: The aims of the study were (a) to examine the final outcome in patients experiencing accidental mucosal perforation during laparoscopic Heller myotomy with Dor fundoplication (LHD) and (b) to evaluate whether perforation episodes might influence the way in which surgeons subsequently approached the LHD procedure. METHODS: We studied all consecutive patients that underwent LHD between 1992 and 2015. Patients were divided into two main groups: those who experienced an intraoperative mucosal perforation (group P) and those whose LHD was uneventful (group NP)...
September 29, 2016: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/27686460/esicm-lives-2016-part-two-milan-italy-1-5-october-2016
#12
S Sivakumar, F S Taccone, K A Desai, C Lazaridis, M Skarzynski, M Sekhon, W Henderson, D Griesdale, L Chapple, A Deane, L Williams, R Strickland, K Lange, D Heyland, M Chapman, M J Rowland, P Garry, J Westbrook, R Corkill, C A Antoniades, K T Pattinson, G Fatania, A J Strong, R B Myers, C Lazaridis, C M Jermaine, C S Robertson, C G Rusin, J Hofmeijer, L Sondag, M C Tjepkema-Cloostermans, A Beishuizen, F H Bosch, M J A M van Putten, L Carteron, C Patet, D Solari, M Oddo, M A Ali, C Dias, R Almeida, A Vaz-Ferreira, J Silva, E Monteiro, A Cerejo, A P Rocha, A A Elsayed, A M Abougabal, B N Beshey, K M Alzahaby, S Pozzebon, A Blandino Ortiz, S Cristallini, O Lheureux, A Brasseur, J L Vincent, J Creteur, F S Taccone, M Hravnak, K Yousef, Y Chang, E Crago, R M Friedlander, S A Abdelmonem, S A Tahon, T A Helmy, H S Meligy, F Puig, I Dunn-Siegrist, J Pugin, S Gupta, D Govil, S Srinivasan, S J Patel, J K N, A Gupta, D S Tomar, M Shafi, R Harne, D P Arora, N Talwar, S Mazumdar, E E Papakrivou, D Makris, E Manoulakas, B Tsolaki, B Karadodas, E Zakynthinos, I Palacios Garcia, A Diaz Martin, V Sanchez Encinares, M Pachón Ibañez, J Garnacho Montero, G Labrador, T Cebrero Cangueiro, V Poulose, J Koh, J W Kam, H Yeter, A Kara, O Aktepe, A Topeli, I Tsolakoglou, G Intas, P Stergiannis, A A Kolaros, E Chalari, E Athanasiadou, A Martika, G Fildisis, V Faivre, C Mengelle, B Favier, D Payen, A Poppe, M S Winkler, E Mudersbach, J Schreiber, M L Wruck, E Schwedhelm, S Kluge, C Zöllner, T Tavladaki, A M Spanaki, H Dimitriou, E Kondili, C Choulaki, E Meleti, D Kafetzopoulos, D Georgopoulos, G Briassoulis, A García-de la Torre, M V de la Torre-Prados, T Tsvetanova-Spasova, P Nuevo-Ortega, C Rueda-Molina, A Fernández-Porcel, E Camara-Sola, L Salido-Díaz, A García-Alcántara, T Tavladaki, A M Spanaki, H Dimitriou, E Kondili, C Choulaki, D E Meleti, D Kafetzopoulos, D Georgopoulos, G Briassoulis, B Suberviola, J Riera, L Rellan, M Sanchez, J C Robles, E Lopez, R Vicente, E Miñambres, M Santibañez, M Le Guen, J Moore, N Mason, M Windpassinger, O Plattner, E Mascha, D I Sessler, Outcomes Research, U Melia, J Fontanet, J P van den Berg, M M R F Struys, H E M Vereecke, E W Jensen, P J T Rood, F van de Schoor, K van Tertholen, P Pickkers, M van den Boogaard, Z J Beardow, H Redhead, K Paramasivam, T Numan, M van den Boogaard, A M Kamper, P Rood, L M Peelen, P M Zeman, A J Slooter, C E van Ewijk, G E Jacobs, A R J Girbes, S N Myatra, M M Harish, N R Prabu, S Siddiqui, A P Kulkarni, J V Divatia, L D Murbach, M A Leite, E F Osaku, C R L M Costa, M Pelenz, N M Neitzke, M M Moraes, J L Jaskowiak, M M M Silva, R S Zaponi, L R L Abentroth, S M Ogasawara, A C Jorge, P A D Duarte, N Hernández-Sánchez, L A Sánchez-Hurtado, F J García-Guillen, S A Ñamendys-Silva, B Maghsoudi, M Emami, M B Khosravi, F Zand, H R Tabatabaie, M Masjedi, G Sabetiyan, A Mokri, J Troubleyn, M Diltoer, R Jacobs, D N Nguyen, E De Waele, J De Regt, P M Honoré, V Van Gorp, H D Spapen, R S Contreras, N D Toapanta, G Moreno, J Sabater, H Torrado, M Gonzalez, M Marin, E Farigola, A Gonzalez, J Fernandez, A Vera, X Gisbert, C Juliá, J Uya, L Corral, I Elias-Jones, L Gemmell, A MacKay, D Randall, A Adwaney, M Blunden, J R Prowle, C J Kirwan, N Thomas, A Martin, H Owen, L Darwin, D Conway, D Atkinson, M Sharman, J Moore, C Barbanti, J Amour, P Gaudard, B Rozec, P Mauriat, M M'rini, P L Leger, G Cambonie, J M Liet, C Girard, S Laroche, P Damas, Z Assaf, G Loron, L Lecourt, P Pouard, D Randall, A Adwaney, M Blunden, J R Prowle, C J Kirwan, S H Kim, S Na, J Kim, S Y Oh, C W Jung, S H Yoo, S H Min, E J Chung, H Lee, N J Lee, K W Lee, K S Suh, H G Ryu, D C Marshall, R J Goodson, J D Salciccioli, J Shalhoub, E K Potter, J Kirk-Bayley, N D Karanjia, L G Forni, B C Creagh-Brown, M Bossy, M Nyman, A Tailor, B Creagh-Brown, D D'Antini, S Spadaro, F Valentino, F Sollitto, G Cinnella, L Mirabella, F J Redondo Calvo, N Bejarano, D Padilla, V Baladron, P Villajero, R Villazala, J Redondo, A S Yuste, J Liu, F Shen, J L Teboul, N Anguel, A Beurton, N Bezaz, C Richard, X Monnet, T Fossali, R Colombo, D Ottolina, M Rossetti, C Mazzucco, A Marchi, A Porta, E Catena, K H Tollisen, G Ø Andersen, F Heyerdahl, D Jacobsen, M C de Waard, A R J Girbes, M C O van IJzendoorn, H Buter, W P Kingma, G J Navis, E C Boerma, J Rulisek, M Balik, S Zacharov, H S Kim, S J Jeon, H Namgung, E Lee, E Lee, Y J Cho, Y J Lee, A Huang, L Cioccari, N Luethi, J Mårtensson, R Bellomo, M Forsberg, G Edman, J Höjer, S Forsberg, M T Chiquito Freile, F N Hidalgo, J A Martinez Molina, R Lecumberri, A Figuerola Rosselló, P Medrano Travieso, G Tuero Leon, J Gonzalez Sanchez, L Sahuquillo Frias, D Balsells Rosello, J A Garcia Verdejo, J A Noria Serrano, D Winterwerp, T van Galen, A Vazin, I Karimzade, A Zand, E Ozen, S Ekemen, A Akcan, E Sen, B Buyukkidan Yelken, N Kureshi, L Fenerty, G Thibault-Halman, M Erdogan, S Walling, R S Green, D B Clarke, P Briassoulis, K Kalimeris, A Ntzouvani, T Nomikos, K Papaparaskeva, E Politi, G Kostopanagiotou, K Crewdson, M Rehn, A Weaver, K Brohi, D Lockey, S Wright, K Thomas, C Baker, L Mansfield, V Stafford, C Wade, G Watson, A Bryant, T Chadwick, J Shen, J Wilkinson, J Furneval, A Henderson, K Hugill, P Howard, A Roy, S Bonner, S Baudouin, C Sánchez Ramírez, S Hípola Escalada, M A Hernández Viera, M Cabrera Santana, L Caipe Balcázar, N Sangil Monroy, F Artiles Campelo, C F Lübbe Vázquez, P Saavedra Santana, S Ruiz Santana, L Carteron, C Patet, H Quintard, D Solari, P Bouzat, M Oddo, T Wollersheim, J Malleike, K Haas, N Carbon, J Schneider, C Birchmeier, J Fielitz, S Spuler, S Weber-Carstens, L Enseñat, A Pérez-Madrigal, P Saludes, L Proença, G Gruartmoner, C Espinal, J Mesquida, W Huber, M Eckmann, F Elkmann, A Gruber, T Lahmer, U Mayr, A Herner, R Schellnegger, J Schneider, R M Schmid, W Ayoub, W Samy, A Esmat, A Battah, S Mukhtar, W Mongkolpun, D Orbegozo Cortés, C P R Cordeiro, J L Vincent, J Creteur, S Funcke, H Groesdonk, B Saugel, G Wagenpfeil, S Wagenpfeil, D A Reuter, M M Fernandez, R Fernandez, M Magret, A González-Castro, M T Bouza, M Ibañez, C García, B Balerdi, A Mas, V Arauzo, J M Añón, F Ruiz, J Ferreres, R Tomás, M Alabert, A I Tizón, S Altaba, N Llamas, E C Goligher, E Fan, M Herridge, S Vorona, M Sklar, M Dres, N Rittayamai, A Lanys, C Urrea, G Tomlinson, W D Reid, G D Rubenfeld, B P Kavanagh, L J Brochard, N D Ferguson, A Serpa Neto, M Gama de Abreu, P Pelosi, M J Schultz, C Guérin, L Papazian, J Reignier, L Ayzac, A Loundou, J M Forel, C Rolland-Debord, C Bureau, T Poitou, M Clavel, S Perbet, N Terzi, A Kouatchet, T Similowski, A Demoule, N Hunfeld, Z Trogrlic, S Ladage, R J Osse, B Koch, W Rietdijk, J Devlin, M van der Jagt, E Picetti, P Ceccarelli, F Mensi, L Malchiodi, S Risolo, I Rossi, M V Antonini, F Servadei, M L Caspani, A Roquilly, S Lasocki, P Seguin, T Geeraerts, P F Perrigault, C Dahyot-Fizelier, C Paugam-Burtz, F Cook, R Cinotti, D Demeure Dit Latte, P J Mahe, C Fortuit, F Feuillet, K Asehnoune, C Marzorati, S Spina, V Scaravilli, A Vargiolu, M Riva, C Giussani, E Sganzerla, G Citerio, S Barbadillo, F J González de Molina, F Álvarez-Lerma, A Rodríguez, T Zakharkina, I Martin-Loeches, S Matamoros, P Povoa, A Torres, J Kastelijn, J J Hofstra, M de Jong, M Schultz, P Sterk, A Artigas, L J Bos, A S Moreau, I Martin-Loeches, P Povoa, J Salluh, A Rodriguez, S Nseir, E de Jong, J A van Oers, A Beishuizen, A R J Girbes, M W N Nijsten, D W de Lange, D Bonvicini, D Labate, L Benacchio, A Olivieri, E Pizzirani, J C Lopez-Delgado, M Gonzalez-Romero, V Fuentes-Mila, D Berbel-Franco, I Romera-Peregrina, A Martinez-Pascual, J Perez-Sanchez, R Abellan-Lencina, R E Ávila-Espinoza, G Moreno-Gonzalez, F Sbraga, S Griffiths, M P W Grocott, B Creagh-Brown, J Doyle, P Wilkerson, Y Soon, S Huddart, M Dickinson, A Riga, A Zuleika, K Miyamoto, Y Kawazoe, T Morimoto, T Yamamoto, A Fuke, A Hashimoto, H Koami, S Beppu, Y Katayama, M Ito, Y Ohta, H Yamamura, S L Rygård, L B Holst, J Wetterslev, P I Johansson, A Perner, I W Soliman, D W de Lange, D van Dijk, J J M van Delden, O L Cremer, A J C Slooter, L M Peelen, D McWilliams, C Snelson, A Das Neves, C I Loudet, M Busico, D Vazquez, D Villalba, M Veronesi, A Lischinsky, F J L López, L Benito Mori, G Plotnikow, A Díaz, S Giannasi, R Hernandez, L Krzisnik, C Cecotti, L Viola, R Lopez, J P Sottile, G Benavent, E Estenssoro, C M Chen, C C Lai, K C Cheng, W Chou, K S Chan, L E Roeker, C M Horkan, F K Gibbons, K B Christopher, P J M Weijs, K M Mogensen, J D Rawn, M K Robinson, K B Christopher, Z Tang, C Qiu, B Ouyang, C Cai, X Guan, T Regueira, L Cea, S Juan Carlos, B Elisa, C Puebla, A Vargas, M K Poulsen, L P Thomsen, S Kjærgaard, S E Rees, D S Karbing, T Wollersheim, S Frank, M C Müller, N M Carbon, V Skrypnikov, P A Pickerodt, R Falk, A Mahlau, S Weber-Carstens, A Lee, R Inglis, R Morgan, G Barker, K Kamata, T Abe, D Saitoh, Y Tokuda, R S Green, M B Butler, M Erdogan, H Tae Hwa, L Jae Gil, R Hernández Vaquero, E Rodriguez-Ruiz, A Lopez Lago, J L Garcia Allut, A Estany Gestal, M A Garcia Gonzalez, D O Thomas-Rüddel, D Schwarzkopf, C Fleischmann, K Reinhart, S Suwanpasu, Y Sattayasomboon, N M Filgueiras Filho, J C A Oliveira, C S Ballalai, C V De Lucia, G P Araponga, L N Veiga, C S Silva, M E Garrido, B B Ramos, E F Ricaldi, S S Gomes, L Gemmell, A MacKay, C Wright, R I Docking, P Doherty, E Black, P Stenhouse, M P Plummer, M E Finnis, L K Phillips, P Kar, S Bihari, V Biradar, S Moodie, M Horowitz, J E Shaw, A M Deane, T Yatabe, S Inoue, M Sakaguchi, M Egi, Y Ali Abdelhamid, M P Plummer, M E Finnis, L K Phillips, P Kar, S Bihari, V Biradar, S Moodie, M Horowitz, J E Shaw, A M Deane, M Hokka, M Egi, S Mizobuchi, P Kar, M Plummer, Y Ali Abdelhamid, E Giersch, M Summers, S Hatzinikolas, S Heller, M Chapman, K Jones, M Horowitz, A Deane, R Schweizer, M Jacquet-Lagreze, P Portran, S Junot, B Allaouchiche, J L Fellahi, P Guerci, B Ergin, A Kapucu, C Ince, L Cioccari, N Luethi, M Crisman, R Bellomo, J Mårtensson, C Righy Shinotsuka, D Fagnoul, A Brasseur, D Orbegozo, J L Vincent, J C Preiser, J C Preiser, O Lheureux, A Thooft, S Brimioulle, J L Vincent, H Iwasaka, S Tahara, M Nagamine, A Ichigatani, A Rugerio Cabrera, E Monares Zepeda, J Franco Granillo, J S Aguirre Sánchez, A A Tanaka Montoya, A Pedraza Montenegro, G A Gálvez Blanco, C M Coronado Robles, A Drolz, T Horvatits, K Roedl, K Rutter, S Kluge, G C Funk, B Schneeweiss, V Fuhrmann, G Sabetian, F Pooresmaeel, F Zand, S Ghaffaripour, A Farbod, H Tabei, L Taheri, R Anandanadesan, V Metaxa, C Teixeira, S M Pereira, P Hernández-Marrero, A S Carvalho, M Beckmann, C S Hartog, D Schwarzkopf, A Raadts, A Robertsen, R Førde, N O Skaga, E Helseth, S Honeybul, K Ho, P Martinez Lopez, M Nieto Gonzalez, P Nuevo Ortega, E Camara Sola, T Spasova, M V de la Torre-Prados, O Kopecky, K Rusinova, P Waldauf, Z Cepeplikova, M Balik, J Palamidessi Domínguez, P Matia Almudevar, S Alcántara Carmona, J J Rubio Muñoz, D Palacios Castañeda, A Naharro Abellán, P Rodríguez Villamizar, J Veganzones Ramos, L Pérez Pérez, A Pérez Lucendo, M Camós Ejarque, A Estella, V Lopez Camps, M C Martín, N Masnou, S Barbosa, A Varela, I Palma, L Cristina, E Nunes, I Pereira, G Campello, C Granja, R Pande, M Pandey, S Varghese, M Chanu, M J Van Dam, E W M T Ter Braak, A Estella, M Gracia, R Viciana, M Recuerda, L Perez Fontaiña, B Tharmalingam, F Kovari, L Rose, M Mcginlay, R Amin, K Burns, B Connolly, N Hart, P Jouvet, S Katz, D Leasa, C Mawdsley, D Mcauley, M Schultz, B Blackwood, S Denham, R Worrall, M Arshad, P Isherwood, A Khadjibaev, D Sabirov, A Rosstalnaya, F Parpibaev, V Sharipova, G A Galvez Blanco, C I Olvera Guzman, J S Aguirre Sánchez, J Franco Granillo, S Gupta, D Govil, S Srinivasan, S J Patel, J K N, A Gupta, M Shafi, D S Tomar, R Harne, D P Arora, N Talwar, S Mazumdar, Y S Cha, S J Lee, N Tyagi, R K Rajput, S Taneja, V K Singh, S C Sharma, S Mittal, B K Rao, J Ayachi, N Fraj, S Romdhani, A Khedher, K Meddeb, N Sma, A Azouzi, R Bouneb, I Chouchene, M El Ghardallou, M Boussarsar, R Jennings, E Walter, J M Ribeiro, I Moniz, R Marçal, A C Santos, C Candeias, Z Costa E Silva, S E Zamora Gomez, O R Perez Nieto, J A Castanon Gonzalez, A I Vasquez Cuellar, H Mildh, V Pettilä, A M Korhonen, S Karlsson, T Ala-Kokko, M Reinikainen, S T Vaara, M Zaleska-Kociecka, M Grabowski, M Dąbrowski, S Wozniak, K Piotrowska, M Banaszewski, J Imiela, J Stepinska, A González Pérez, P Florez Ordoñez, A Giribet, M A Alonso Cuervo, R Alonso Cuervo, M A Rodriguez Esteban, L Iglesias Fraile, C Ponte Mittelbrum, G Muñiz Albaiceta, J Koeze, F Keus, W Dieperink, I C C van der Horst, M van Meurs, J G Zijlstra, S Roberts, C Hernandez Caballero, G Isgro, D Hall, S Beitland, A-M S Trøseid, B S Brusletto, B E Waldum-Grevbo, J P Berg, K Sunde, D García Huertas, F Manzano, M M Jiménez- Quintana, A Osuna, F Santiago-Ruiz, C Rodríguez-Mejías, R Wangensteen, H R Jamaati, M Masjedi, F Zand, S M R Hashemian, G Sabetian, G Abbasi, V Khaloo, S H A Tabei, A 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No abstract text is available yet for this article.
September 2016: Intensive Care Medicine Experimental
https://www.readbyqxmd.com/read/27686458/esicm-lives-2016-part-one-milan-italy-1-5-october-2016
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Garcia Marin, G J Echeverry, W F Bermudez, H J Madriñan-Navia, J D Valencia, E Quiñonez, A Marulanda, C A Arango-Dávila, A Bruhn, G Hernandez, D De Backer, D Orbegozo Cortes, F Su, J L Vincent, J Creteur, L Tullo, L Mirabella, P Di Molfetta, G Cinnella, M Dambrosio, C Villavicencio Lujan, J Leache Irigoyen, M Cartanya Ferré, R Carbonell García, A Mukhtar, M Ahmed, M El Ayashi, A Hasanin, E Ayman, M Salem, A Eladawy, S Fathy, H Nassar, A Zaghlol, M F Aguilar Arzapalo, Å Valsø, K Sunde, T Rustøen, I Schou-Bredal, L Skogstad, K Tøien, C Padilla, Y Palmeiro, W Egbaria, R Kigli, B Maertens, K Blot, S Blot, E Santana-Santos, E R Dos Santos, R E D L Ferretti-Rebustini, R D C C D O Dos Santos, R G S Verardino, L A Bortolotto, A M Doyle, I Naldrett, J Tillman, S Price, S Shrestha, P Pearson, J Greaves, D Goodall, A Berry, A Richardson, G O Odundo, P Omengo, P Obonyo, N M Chanzu, R Kleinpell, S J Sarris, P Nedved, M Heitschmidt, H Ben-Ghezala, S Snouda, S Djobbi, H Ben-Ghezala, S Snouda, L Rose, N K J Adhikari, D Leasa, D Fergusson, D A Mckim, J Weblin, O Tucker, D McWilliams, F Doesburg, F Cnossen, W Dieperink, W Bult, M W N Nijsten, G A Galvez-Blanco, E Monares Zepeda, C I Olvera Guzman, J S Aguirre Sánchez, J Franco Granillo, J Santos Stroud, R Thomson, M Llaurado-Serra, A Lobo-Civico, M Pi-Guerrero, I Blanco-Sanchez, A Piñol-Tena, C Paños-Espinosa, Y Alabart-Segura, B Coloma-Gomez, A Fernandez-Blanco, F Braga-Dias, M Treso-Geira, A Valeiras-Valero, L Martinez-Reyes, A Sandiumenge, M F Jimenez-Herrera, R Prada, P Juárez, R Argandoña, J J Díaz, C Sánchez Ramirez, P Saavedra, S Ruiz Santana, O Obukhova, S Kashiya, I A Kurmukov, A M Pronina, P Simeone, L Puybasset, G Auzias, O Coulon, B Lesimple, G Torkomian, L Velly, A Bienert, A Bartkowska-Sniatkowska, P Wiczling, O Szerkus, D Siluk, J Bartkowiak-Wieczorek, J Rosada-Kurasinska, J Warzybok, A Borsuk, R Kaliszan, E Grzeskowiak, C Hernandez Caballero, S Roberts, G Isgro, D Hall, G Guillaume, O Passouant, F Dumas, W Bougouin, B Champigneulle, M Arnaout, J Chelly, J D Chiche, O Varenne, J P Mira, E Marijon, A Cariou, M Beerepoot, H R Touw, K Parlevliet, C Boer, P W Elbers, P R Tuinman, Á J Roldán Reina, Y Corcia Palomo, R Martín Bermúdez, L Martín Villén, I Palacios García, J R Naranjo Izurieta, J B Pérez Bernal, F J Jiménez Jiménez, F Cota-Delgado, M V de la Torre-Prados, A Fernández-Porcel, P Nuevo-Ortega, E Cámara-Sola, T Tsvetanova-Spasova, C Rueda-Molina, L Salido-Díaz, A García-Alcántara, T Kaneko, H Tanaka, M Kamikawa, R Karashima, S Iwashita, H Irie, S Kasaoka, O Arola, R Laitio, A Saraste, J Airaksinen, M Pietilä, M Hynninen, J Wennervirta, M Bäcklund, E Ylikoski, P Silvasti, E Nukarinen, J Grönlund, V P Harjola, J Niiranen, K Korpi, M Varpula, R O Roine, T Laitio, S Salah, B G Hassen, A Mohamed Fehmi, S Kim, Y C Hsu, J Barea-Mendoza, C García-Fuentes, M Castillo-Jaramillo, H Dominguez-Aguado, R Viejo-Moreno, L Terceros-Almanza, S Bermejo Aznárez, C Mudarra-Reche, W Xu, M Chico-Fernández, J C Montejo-González, K Crewdson, M Thomas, M Merghani, L Fenner, P Morgan, D Lockey, E J van Lieshout, B Oomen, J M Binnekade, D A Dongelmans, R J de Haan, N P Juffermans, M B Vroom, R Algarte, L Martínez, B Sánchez, I Romero, F Martínez, S Quintana, J Trenado, O Sheikh, D Pogson, R Clinton, F Riccio, L Gemmell, A MacKay, A Arthur, L Young, A Sinclair, D Markopoulou, K Venetsanou, L Filippou, E Salla, S Stratouli, I Alamanos, A H Guirgis, R Gutiérrez Rodriguez, M J Furones Lorente, I Macias Guarasa, A Ukere, S Meisner, G Greiwe, B Opitz, D Benten, B Nashan, L Fischer, C J C Trepte, D A Reuter, S A Haas, C R Behem, G Tavazzi, B Ana, A Vazir, D Gibson, S Price, M Masjedi, M R Hadavi, M Riahi Alam, M R Sasani, N Parenti, F Agrusta, C Palazzi, B Pifferi, R Sganzerla, F Tagliazucchi, A Luciani, M Möller, J Müller-Engelmann, G Montag, P Adams, C Lange, J Neuzner, R Gradaus, K H Wodack, F Thürk, A D Waldmann, M F Grässler, S Nishimoto, S H Böhm, E Kaniusas, D A Reuter, C J Trepte, T Sigmundsson, T Öhman, E Redondo, M Hallbäck, M Wallin, F Suarez Sipman, A Oldner, C Hällsjö Sander, H Björne, L Colinas, G Hernandez, R Vicho, M Serna, R Cuena, A Canabal, A Chaari, K Abdel Hakim, M Etman, M El Bahr, A El Sakka, K Bousselmi, A Arali, V Kauts, W F Casey, O Bond, P De Santis, E Iesu, F Franchi, J L Vincent, J Creteur, S Scolletta, F S Taccone, Z Marutyan, L Hamidova, A Shakotko, V Movsisyan, I Uysupova, A Evdokimov, S Petrikov, C Gonen, E Haftacı, C Balci, F J Redondo Calvo, N Bejarano, V Baladron, R Villazala, J Redondo, D Padilla, P Villarejo, A Akcan-Arikan, C E Kennedy, M F Aguilar Arzapalo, C Gomez-Gonzalez, S Mas-Font, A Puppo-Moreno, M Herrera-Gutierrez, M Garcia-Garcia, S Aldunate-Calvo, E P Plata-Menchaca, X L Pérez-Fernández, M Estruch, A Betbese-Roig, P Cárdenas Campos, M Rojas Lora, N D Toapanta Gaibor, R S Contreras Medina, V D Gumucio Sanguino, E J Casanova, J Sabater Riera, K Kritmetapak, S Peerapornratana, P Kittiskulnam, T Dissayabutra, K Tiranathanagul, P Susantithapong, K Praditpornsilpa, K Tungsanga, S Eiam-Ong, N Srisawat, T Winkelmann, T Busch, J Meixensberger, S Bercker, E M Flores Cabeza, M Sánchez Sánchez, N Cáceres Giménez, C Gutierrez Melón, E Herrero de Lucas, P Millán Estañ, M Hernández Bernal, A Garcia de Lorenzo Y Mateos, B Ergin, P Guerci, P A C Specht, Y Ince, C Ince, M Balik, M Zakharchenko, F Los, H Brodska, C de Tymowski, P Augustin, M Desmard, P Montravers, S N Stapel, R de Boer, H M Oudemans, A Hollinger, T Schweingruber, F Jockers, M Dickenmann, M Siegemund, N Runciman, M Ralston, R Appleton, T Mauri, L Alban, C Turrini, T Sasso, T Langer, M Panigada, P Taccone, E Carlesso, C Marenghi, G Grasselli, A Pesenti, P Wibart, T Reginault, M Garcia, B Barbrel, A Benard, C Bader, F Vargas, H N Bui, G Hilbert, J M Serrano Simón, P Carmona Sánchez, F Ruiz Ferrón, M García de Acilu, J Marin, V Antonia, L Ruano, M Monica, R Ferrer, J R Masclans, O Roca, G Hong, D H Kim, Y S Kim, J S Park, Y K Jee, Z Yu Xiang, W Jia-Xing, W Xiao 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Gerretsen, Q de Mast, S El Messaoudi, G Rongen, M Gomes, M Kox, P Pickkers, N P Riksen, Y Kashiwagi, M Okada, K Hayashi, Y Inagaki, S Fujita, M N Nakamae, Y R Kang, R B Souza, A M A Liberatore, I H J Koh, A Blet, M Sadoune, J Lemarié, N Bihry, R Bern, E Polidano, R Merval, J M Launay, B Lévy, J L Samuel, A Mebazaa, J Hartmann, S Harm, V Weber
No abstract text is available yet for this article.
September 2016: Intensive Care Medicine Experimental
https://www.readbyqxmd.com/read/27672641/small-bowel-entrapment-and-ureteropelvic-junction-disruption-associated-with-l3-chance-fracture-dislocation
#14
Sebastien Pesenti, Benjamin Blondel, Alice Faure, Emilie Peltier, Franck Launay, Jean-Luc Jouve
Paediatric Chance fracture are rare lesions but often associated with abdominal injuries. We herein present the case of a seven years old patient who sustained an entrapment of small bowel and an ureteropelvic disruption associated with a Chance fracture and spine dislocation following a traffic accident. Initial X-rays and computed tomographic (CT) scan showed a Chance fracture with dislocation of L3 vertebra, with an incarceration of a small bowel loop in the spinal canal and a complete section of the left lumbar ureter...
September 16, 2016: World Journal of Clinical Cases
https://www.readbyqxmd.com/read/27626833/mechanical-ventilation-to-minimize-progression-of-lung-injury-in-acute-respiratory-failure
#15
Laurent Brochard, Arthur Slutsky, Antonio Pesenti
Mechanical Ventilation (MV) is used to sustain life in patients with acute respiratory failure. A major concern in mechanically ventilated patients is the risk of Ventilator-Induced Lung Injury (VILI), which is partially prevented by lung protective ventilation. Spontaneously breathing, non-intubated, patients with acute respiratory failure may have a high respiratory drive and breathe with large tidal volumes and potentially injurious transpulmonary pressure swings. In patients with existing lung injury, regional forces generated by the respiratory muscles may lead to injurious effects on a regional level...
September 14, 2016: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/27586996/associations-between-ventilator-settings-during-extracorporeal-membrane-oxygenation-for-refractory-hypoxemia-and-outcome-in-patients-with-acute-respiratory-distress-syndrome-a-pooled-individual-patient-data-analysis-mechanical-ventilation-during-ecmo
#16
Ary Serpa Neto, Matthieu Schmidt, Luciano C P Azevedo, Thomas Bein, Laurent Brochard, Gernot Beutel, Alain Combes, Eduardo L V Costa, Carol Hodgson, Christian Lindskov, Matthias Lubnow, Catherina Lueck, Andrew J Michaels, Jose-Artur Paiva, Marcelo Park, Antonio Pesenti, Tài Pham, Michael Quintel, V Marco Ranieri, Michael Ried, Roberto Roncon-Albuquerque, Arthur S Slutsky, Shinhiro Takeda, Pier Paolo Terragni, Marie Vejen, Steffen Weber-Carstens, Tobias Welte, Marcelo Gama de Abreu, Paolo Pelosi, Marcus J Schultz
PURPOSE: Extracorporeal membrane oxygenation (ECMO) is a rescue therapy for patients with acute respiratory distress syndrome (ARDS). The aim of this study was to evaluate associations between ventilatory settings during ECMO for refractory hypoxemia and outcome in ARDS patients. METHODS: In this individual patient data meta-analysis of observational studies in adult ARDS patients receiving ECMO for refractory hypoxemia, a time-dependent frailty model was used to determine which ventilator settings in the first 3 days of ECMO had an independent association with in-hospital mortality...
September 1, 2016: Intensive Care Medicine
https://www.readbyqxmd.com/read/27580032/insights-from-biochemical-reconstitution-into-the-architecture-of-human-kinetochores
#17
John R Weir, Alex C Faesen, Kerstin Klare, Arsen Petrovic, Federica Basilico, Josef Fischböck, Satyakrishna Pentakota, Jenny Keller, Marion E Pesenti, Dongqing Pan, Doro Vogt, Sabine Wohlgemuth, Franz Herzog, Andrea Musacchio
Chromosomes are carriers of genetic material and their accurate transfer from a mother cell to its two daughters during cell division is of paramount importance for life. Kinetochores are crucial for this process, as they connect chromosomes with microtubules in the mitotic spindle. Kinetochores are multi-subunit complexes that assemble on specialized chromatin domains, the centromeres, that are able to enrich nucleosomes containing the histone H3 variant centromeric protein A (CENP-A). A group of several additional CENPs, collectively known as constitutive centromere associated network (CCAN), establish the inner kinetochore, whereas a ten-subunit assembly known as the KMN network creates a microtubule-binding site in the outer kinetochore...
August 31, 2016: Nature
https://www.readbyqxmd.com/read/27565373/reduced-kinase-activity-of-polo-kinase-cdc5-affects-chromosome-stability-and-dna-damage-response-in-s-cerevisiae
#18
Chetan C Rawal, Sara Riccardo, Chiara Pesenti, Matteo Ferrari, Federica Marini, Achille Pellicioli
Polo-like kinases (PLKs) control several aspects of eukaryotic cell division and DNA damage response. Remarkably, PLKs are overexpressed in several types of cancer, being therefore a marker of bad prognosis. As such, specific PLK kinase activity inhibitors are already used in clinical trials and the regulation of PLK activation is a relevant topic of cancer research. Phosphorylation of threonine residues in the T-loop of the kinase domain is pivotal for PLKs activation. Here, we show that T238A substitution in the T-loop reduces the kinase activity of Cdc5, the only PLK in Saccharomyces cerevisiae, with minor effect on cell growth in unperturbed conditions...
November 2016: Cell Cycle
https://www.readbyqxmd.com/read/27546769/a-mathematical-model-of-oxygenation-during-venovenous-extracorporeal-membrane-oxygenation-support
#19
Alberto Zanella, Domenico Salerno, Vittorio Scaravilli, Marco Giani, Luigi Castagna, Federico Magni, Eleonora Carlesso, Paolo Cadringher, Michela Bombino, Giacomo Grasselli, Nicolò Patroniti, Antonio Pesenti
PURPOSE: To develop a mathematical model of oxygenation during venovenous extracorporeal membrane oxygenation (vv-ECMO). MATERIAL AND METHODS: Total oxygen consumption, cardiac output, blood flow, recirculation, intrapulmonary shunt, hemoglobin, natural lung, and membrane lung oxygen fractions were chosen as inputs. Content, partial pressure, and hemoglobin saturation of oxygen in arterial, venous, pulmonary, and extracorporeal blood were outputs. To assess accuracy and predictive power of the model, we retrospectively analyzed data of 25 vv-ECMO patients...
July 15, 2016: Journal of Critical Care
https://www.readbyqxmd.com/read/27518321/bedside-assessment-of-the-effects-of-positive-end-expiratory-pressure-on-lung-inflation-and-recruitment-by-the-helium-dilution-technique-and-electrical-impedance-tomography
#20
Tommaso Mauri, Nilde Eronia, Cecilia Turrini, Marta Battistini, Giacomo Grasselli, Roberto Rona, Carlo Alberto Volta, Giacomo Bellani, Antonio Pesenti
PURPOSE: Higher positive end-expiratory pressure might induce lung inflation and recruitment, yielding enhanced regional lung protection. We measured positive end-expiratory pressure-related lung volume changes by electrical impedance tomography and by the helium dilution technique. We also used electrical impedance tomography to assess the effects of positive end-expiratory pressure on regional determinants of ventilator-induced lung injury. METHODS: A prospective randomized crossover study was performed on 20 intubated adult patients: 12 with acute hypoxemic respiratory failure and 8 with acute respiratory distress syndrome...
October 2016: Intensive Care Medicine
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