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JOURNAL ARTICLE
I want to be safe: understanding the main drivers behind vaccination choice throughout the pandemic.
Marco Marini, Alessandro Demichelis, Dario Menicagli, Giovanna Mancini, Folco Panizza, Ennio Bilancini, Gustavo Cevolani
BACKGROUND: Despite being a major advancement in modern medicine, vaccines face widespread hesitancy and refusal, posing challenges to immunization campaigns. The COVID-19 pandemic accentuated vaccine hesitancy, emphasizing the pivotal role of beliefs in efficacy and safety on vaccine acceptance rates. This study explores the influence of efficacy and safety perceptions on vaccine uptake in Italy during the pandemic. METHODS: We administered a 70-item questionnaire to a representative sample of 600 Italian speakers...
April 22, 2024: BMC Public Health
#2
JOURNAL ARTICLE
Vittoria Rizzello, Maria Denitza Tinti, Mauro Gori, Marco Marini, Vittorio Palmieri, Luisa De Gennaro, Paolo Manca, Maria Vittoria Matassini, Concetta Di Nora, Matteo Bianco, Samuela Carigi, Piero Gentile, Giuseppe Leonardi, Francesco Orso, Marco Gorini, Lucio Gonzini, Donata Lucci, Aldo Pietro Maggioni, Renata De Maria, Luigi Tavazzi
The Italian Network on Congestive Heart Failure (IN-CHF) project, later known as IN-HF Online, was launched in 1995 to provide the Italian cardiology community with a digital tool, standardized across the country, for managing outpatients with heart failure (HF), that enabled the creation of a database for clinical, educational and scientific purposes. During its almost three decades of activity, this observational research program has achieved highly positive scientific results. Indeed, IN-HF fostered professional relationships among individuals working in different centers, established a cultural network for the care of HF patients, periodically updated on the scientific advances, and allowed the assessment of several clinical, epidemiological, and prognostic features...
May 2024: Giornale Italiano di Cardiologia
#3
JOURNAL ARTICLE
Chia Yaw Teoh, Evelyn Li Min Tai, Wan Mariny Wan Md Kasim
No abstract text is available yet for this article.
April 1, 2024: JAMA Ophthalmology
#4
REVIEW
Lauren Dietz, Jessica Marini, Hamza Hashmi, Mary McGann
High-dose chemotherapy followed by autologous hematopoietic stem cell transplantation is the standard of care for eligible patients with newly diagnosed multiple myeloma leading to prolonged progression free and overall survival. Successful engraftment following hematopoietic stem cell infusion requires adequate stem cell doses. Current mobilization regimens include granulocyte colony-stimulating factor (G-CSF) with or without plerixafor. Motixafortide is a recently approved agent that can be used in combination with G-CSF for mobilization...
April 17, 2024: Journal of Oncology Pharmacy Practice
#5
MULTICENTER STUDY
Gennaro Perrone, Mario Giuffrida, Fikri Abu-Zidan, Vitor F Kruger, Marco Livrini, Gabriele Luciano Petracca, Giorgio Rossi, Antonio Tarasconi, Brian W C A Tian, Elena Bonati, Ricardo Mentz, Federico N Mazzini, Juan P Campana, Elisabeth Gasser, Reinhold Kafka-Ritsch, Daniel M Felsenreich, Christopher Dawoud, Stefan Riss, Carlos Augusto Gomes, Felipe Couto Gomes, Ricardo Alessandro Teixeira Gonzaga, Cassio Alfred Brattig Canton, Bruno Monteiro Pereira, Gustavo P Fraga, Leticia Gonçalves Zem, Vinicius Cordeiro-Fonseca, Renato de Mesquita Tauil, Boyko Atanasov, Nikolay Belev, Nikola Kovachev, L Juan José Meléndez, Ana Dimova, Stefan Dimov, Zdravko Zelić, Goran Augustin, Branko Bogdanić, Trpimir Morić, Elie Chouillard, Melinda Bajul, Belinda De Simone, Yves Panis, Francesco Esposito, Margherita Notarnicola, Lelde Lauka, Anna Fabbri, Hassen Hentati, Iskander Fnaiech, Venara Aurélien, Marie Bougard, Maxime Roulet, Zaza Demetrashvili, Irakli Pipia, Giorgi Merabishvili, Konstantinos Bouliaris, Georgios Koukoulis, Christos Doudakmanis, Sofia Xenaki, Emmanuel Chrysos, Stamatios Kokkinakis, Panteleimon Vassiliu, Nikolaos Michalopoulos, Ioannis Margaris, Aristotelis Kechagias, Konstantinos Avgerinos, Jevgeni Katunin, Eftychios Lostoridis, Eleni-Aikaterini Nagorni, Antonio Pujante, Francesk Mulita, Ioannis Maroulis, Michail Vailas, Athanasios Marinis, Ioannis Siannis, Eirini Bourbouteli, Dimitrios K Manatakis, Nikolaos Tasis, Vasileios Acheimastos, Sotiropoulou Maria, Kapiris Stylianos, Harilaos Kuzeridis, Dimitrios Korkolis, Evangelos Fradelos, George Kavalieratos, Thalia Petropoulou, Andreas Polydorou, Ioannis Papacostantinou, Tania Triantafyllou, Despina Kimpizi, Dimitrios Theodorou, Konstantinos Toutouzas, Alexandros Chamzin, Maximos Frountzas, Dimitrios Schizas, Ioannis Karavokyros, Athanasios Syllaios, Alexandros Charalabopoulos, Maria Boura, Efstratia Baili, Orestis Ioannidis, Lydia Loutzidou, Elissavet Anestiadou, Ioannis Tsouknidas, Georgios Petrakis, Eleni Polenta, Lovenish Bains, Rahul Gupta, Sudhir K Singh, Archana Khanduri, Miklosh Bala, Asaf Kedar, Marcello Pisano, Mauro Podda, Adolfo Pisanu, Gennaro Martines, Giuseppe Trigiante, Giuliano Lantone, Antonino Agrusa, Giuseppe Di Buono, Salvatore Buscemi, Massimiliano Veroux, Rossella Gioco, Gastone Veroux, Luigi Oragano, Sandro Zonta, Federico Lovisetto, Carlo V Feo, Antonio Pesce, Nicolò Fabbri, Giulio Lantone, Fabio Marino, Fabrizio Perrone, Leonardo Vincenti, Vincenzo Papagni, Arcangelo Picciariello, Stefano Rossi, Biagio Picardi, Simone Rossi Del Monte, Diego Visconti, Giulia Osella, Luca Petruzzelli, Giusto Pignata, Jacopo Andreuccetti, Rossella D'Alessio, Massimo Buonfantino, Eleonora Guaitoli, Stefano Spinelli, Gianluca Matteo Sampietro, Carlo Corbellini, Leonardo Lorusso, Alice Frontali, Isabella Pezzoli, Alessandro Bonomi, Andrea Chierici, Christian Cotsoglou, Giuseppe Manca, Antonella Delvecchio, Nicola Musa, Massimiliano Casati, Laface Letizia, Emmanuele Abate, Giorgio Ercolani, Fabrizio D'Acapito, Leonardo Solaini, Gianluca Guercioni, Simone Cicconi, Diego Sasia, Felice Borghi, Giorgio Giraudo, Giuseppe Sena, Pasquale Castaldo, Eugenia Cardamone, Giuseppe Portale, Matteo Zuin, Ylenia Spolverato, Marialusia Esposito, Roberta Maria Isernia, Maria Di Salvo, Romina Manunza, Giuseppe Esposito, Marcello Agus, Emanuele Luigi Giuseppe Asti, Daniele Tiziano Bernardi, Tommaso Panici Tonucci, Davide Luppi, Massimiliano Casadei, Stefano Bonilauri, Angela Pezzolla, Annunziata Panebianco, Rita Laforgia, Maurizio De Luca, Monica Zese, Dario Parini, Elio Jovine, Giuseppina De Sario, Raffaele Lombardi, Giovanni Aprea, Giuseppe Palomba, Marianna Capuano, Giulio Argenio, Gianluca Orio, Mariano Fortunato Armellino, Marina Troian, Martina Guerra, Carlo Nagliati, Alan Biloslavo, Paola Germani, Giada Aizza, Igor Monsellato, Ali Chaouki Chahrour, Gabriele Anania, Cristina Bombardini, Francesco Bagolini, Gabriele Sganga, Pietro Fransvea, Valentina Bianchi, Paolo Boati, Francesco Ferrara, Francesco Palmieri, Pasquale Cianci, Domenico Gattulli, Enrico Restini, Nicola Cillara, Alessandro Cannavera, Gabriela Elisa Nita, Jlenia Sarnari, Francesco Roscio, Federico Clerici, Ildo Scandroglio, Stefano Berti, Alessandro Cadeo, Alice Filippelli, Luigi Conti, Carmine Grassi, Gaetano Maria Cattaneo, Marina Pighin, Davide Papis, Giovanni Gambino, Vanessa Bertino, Domenico Schifano, Daniela Prando, Luisella Fogato, Fabio Cavallo, Luca Ansaloni, Roberto Picheo, Nicholas Pontarolo, Norma Depalma, Marcello Spampinato, Stefano D'Ugo, Luca Lepre, Michela Giulii Capponi, Rossella Domenica Campa, Giuliano Sarro, Vincenza Paola Dinuzzi, Stefano Olmi, Matteo Uccelli, Davide Ferrari, Marco Inama, Gianluigi Moretto, Michele Fontana, Francesco Favi, Erika Picariello, Alessia Rampini, Andrea Barberis, Antonio Azzinnaro, Alba Oliva, Luigi Totaro, Ilaria Benzoni, Valerio Ranieri, Gabriella Teresa Capolupo, Filippo Carannante, Marco Caricato, Maurizio Ronconi, Silvia Casiraghi, Giovanni Casole, Desire Pantalone, Giovanni Alemanno, Maximilian Scheiterle, Marco Ceresoli, Marco Cereda, Chiara Fumagalli, Federico Zanzi, Stefano Bolzon, Enrico Guerra, Francesca Lecchi, Paola Cellerino, Antonella Ardito, Rosa Scaramuzzo, Andrea Balla, Pasquale Lepiane, Nicola Tartaglia, Antonio Ambrosi, Giovanna Pavone, Gian Marco Palini, Simone Veneroni, Gianluca Garulli, Claudio Ricci, Beatrice Torre, Iris Shari Russo, Matteo Rottoli, Marta Tanzanu, Angela Belvedere, Marco Milone, Michele Manigrasso, Giovanni Domenico De Palma, Micaela Piccoli, Gianmaria Casoni Pattacini, Stefano Magnone, Paolo Bertoli, Michele Pisano, Paolo Massucco, Marco Palisi, Andrea-Pierre Luzzi, Francesco Fleres, Guglielmo Clarizia, Alessandro Spolini, Yoshiro Kobe, Takayuki Toma, Fumihiko Shimamura, Robert Parker, Sinkeet Ranketi, Mercy Mitei, Saulius Svagzdys, Henrikas Pauzas, Justas Zilinskas, Tomas Poskus, Marius Kryzauskas, Matas Jakubauskas, Andee Dzulkarnaen Zakaria, Zaidi Zakaria, Michael Pak-Kai Wong, Asri Che Jusoh, Muhammad Nazreen Zakaria, Daniel Rios Cruz, Aurea Barbara Rodriguez Elizalde, Alejandro Bañon Reynaud, Edgard Efren Lozada Hernandez, Jose Maria Victor Palomo Monroy, Diego Hinojosa-Ugarte, Martha Quiodettis, María Esther Du Bois, José Latorraca, Piotr Major, Michał Pędziwiatr, Magdalena Pisarska-Adamczyk, Maciej Walędziak, Andrzej Kwiatkowski, Łukasz Czyżykowski, Silvia Dantas da Costa, Bela Pereira, Ana Rita Oliveira Ferreira, Filipe Almeida, Ricardo Rocha, Carla Carneiro, Diego Pita Perez, João Carvas, Catarina Rocha, Cátia Ferreira, Rita Marques, Urânia Fernandes, Pedro Leao, André Goulart, Rita Gonçalves Pereira, Sara Daniela Direito Patrocínio, Nuno Gonçalo Gonçalves de Mendonça, Maria Isabel Cerqueira Manso, Henrique Manuel Cardoso Morais, Paulo Sebastião Cardoso, Valentin Calu, Adrian Miron, Elena Adelina Toma, Mahir Gachabayov, Abakar Abdullaev, Andrey Litvin, Taras Nechay, Alexander Tyagunov, Anvar Yuldashev, Alison Bradley, Michael Wilson, Arpád Panyko, Zuzana Látečková, Vladimír Lacko, Dusan Lesko, Marek Soltes, Jozef Radonak, Victor Turrado-Rodriguez, Roser Termes-Serra, Xavier Morales-Sevillano, Pierfrancesco Lapolla, Andrea Mingoli, Gioia Brachini, Maurizio Degiuli, Silvia Sofia, Rossella Reddavid, Andrea de Manzoni Garberini, Angelica Buffone, Eduardo Perea Del Pozo, Daniel Aparicio-Sánchez, Sandra Dos Barbeito, Mercedes Estaire-Gómez, Rebeca Vitón-Herrero, Mª de Los Ángeles Gil Olarte-Marquez, José Gil-Martínez, Felipe Alconchel, Tatiana Nicolás-López, Aida Cristina Rahy-Martin, María Pelloni, Raquel Bañolas-Suarez, Fernando Mendoza-Moreno, Francisca García-Moreno Nisa, Manuel Díez-Alonso, María Elisa Valle Rodas, María Carmona Agundez, María Inmaculada Pérez Andrés, Claudia Cristina Lopes Moreira, Aintzane Lizarazu Perez, Iñigo Augusto Ponce, Ana María González-Castillo, Estela Membrilla-Fernández, Silvia Salvans, Mario Serradilla-Martín, Pablo Sancho Pardo, Daniel Rivera-Alonso, Jana Dziakova, Jose Mugüerza Huguet, Naila Pagès Valle, Enrique Colás Ruiz, Cristina Rey Valcárcel, Cristina Ruiz Moreno, Yeniffer Tatiana Moreno Salazar, Juan Jesús Rubio García, Silvia Sevila Micó, Joaquín Ruiz López, Silvia Pérez Farré, Maite Santamaria Gomez, Nuria Mestres Petit, Alberto Titos-García, Jose Manuel Aranda-Narváez, Laura Romacho-López, Luis Sánchez-Guillén, Veronica Aranaz-Ostariz, Marina Bosch-Ramírez, Aleix Martínez-Pérez, Elías Martínez-López, Juan Carlos Sebastián-Tomás, Granada Jimenez-Riera, Javier Jimenez-Vega, Jose Aurelio Navas Cuellar, Andrea Campos-Serra, Anna Muñoz-Campaña, Raquel Gràcia-Roman, Javier Martínez Alegre, Francisca Lima Pinto, Sara Nuñez O'Sullivan, Francisco Blanco Antona, Beatriz Muñoz Jiménez, Jaime López-Sánchez, Zahira Gómez Carmona, Rocio Torres Fernández, Isabel Blesa Sierra, Laura Román García de León, Verónica Polaino Moreno, Eva Iglesias, Paola Lora Cumplido, Altea Arango Bravo, Ignacio Rey Simó, Carlota López Domínguez, Aloia Guerreiro Caamaño, Rafael Calleja Lozano, Manuel Durán Martínez, Álvaro Naranjo Torres, Javier Tomas Morales Bernaldo de Quiros, Gianluca Pellino, Miriam Moratal Cloquell, Elsa García Moller, Sami Jalal-Eldin, Ahmed K Abdoun, Hytham K S Hamid, Varut Lohsiriwat, Aitsariya Mongkhonsupphawan, Oussama Baraket, Karim Ayed, Imed Abbassi, Ali Ben Ali, Houssem Ammar, Ali Kchaou, Ahmed Tlili, Imen Zribi, Elif Colak, Suleyman Polat, Zehra Alan Koylu, Ali Guner, Mehmet Arif Usta, Murat Emre Reis, Baris Mantoglu, Emre Gonullu, Emrah Akin, Fatih Altintoprak, Zulfu Bayhan, Necattin Firat, Arda Isik, Ufuk Memis, Mehmet Bayrak, Yasemin Altıntaş, Yasin Kara, Mehmet Abdussamet Bozkurt, Ali Kocataş, Koray Das, Ahmet Seker, Nazmi Ozer, Semra Demirli Atici, Korhan Tuncer, Tayfun Kaya, Zeynep Ozkan, Onur Ilhan, Ibrahim Agackiran, Mustafa Yener Uzunoglu, Eren Demirbas, Yuksel Altinel, Serhat Meric, Nadir Adnan Hacım, Derya Salim Uymaz, Nail Omarov, Emre Balık, Giovanni D Tebala, Hany Khalil, Mridul Rana, Mansoor Khan, Charlotte Florence, Christie Swaminathan, Cosimo Alex Leo, Lampros Liasis, Josef Watfah, Ivan Trostchansky, Edward Delgado, Marcelo Pontillo, Rifat Latifi, Raul Coimbra, Sara Edwards, Ana Lopez, George Velmahos, Ander Dorken, Anthony Gebran, Amanda Palmer, Jeffrey Oury, James M Bardes, Sirivan Suon Seng, Lauren S Coffua, Asanthi Ratnasekera, Tanya Egodage, Karla Echeverria-Rosario, Isabella Armento, Lena M Napolitano, Naveen F Sangji, Mark Hemmila, Jacob A Quick, Tyler R Austin, Theodore S Hyman, William Curtiss, Amanda McClure, Nicholas Cairl, Walter L Biffl, Hung P Truong, Kathryn Schaffer, Summer Reames, Filippo Banchini, Patrizio Capelli, Federico Coccolini, Massimo Sartelli, Francesca Bravi, Carlo Vallicelli, Vanni Agnoletti, Gian Luca Baiocchi, Fausto Catena
BACKGROUND: Literature suggests colonic resection and primary anastomosis (RPA) instead of Hartmann's procedure (HP) for the treatment of left-sided colonic emergencies. We aim to evaluate the surgical options globally used to treat patients with acute left-sided colonic emergencies and the factors that leading to the choice of treatment, comparing HP and RPA. METHODS: This is a prospective, international, multicenter, observational study registered on ClinicalTrials...
April 16, 2024: World Journal of Emergency Surgery: WJES
#6
EDITORIAL
James A Davis, Mary McGann, Jessica Marini, Hamza Hashmi
No abstract text is available yet for this article.
April 16, 2024: Expert Review of Anticancer Therapy
#7
JOURNAL ARTICLE
Massimiliano Maines, Francesco Rotondi, Fabrizio Guarracini, Cristina Esposito, Francesco Peruzza, Paolo Vitillo, Nertil Kola, Silvia Quintarelli, Fabio Franculli, Paola Napoli, Daniele Giacopelli, Maurizio Del Greco, Emilio Di Lorenzo, Massimiliano Marini
AIMS: In this study, we investigated a cohort of unselected patients with various indications for an implantable cardiac monitor (ICM). Our main objectives were to determine the incidence of arrhythmic diagnoses, both anticipated and incidental in relation to the ICM indication, and to assess their clinical relevance. METHODS: We examined remote monitoring transmissions from patients with an ICM at four Italian sites to identify occurrences of cardiac arrhythmias...
April 9, 2024: Journal of Cardiovascular Medicine
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JOURNAL ARTICLE
Hanako Ishimaru, Mitsuhiro Nishimura, Hideki Shigematsu, Maria Istiqomah Marini, Natsumi Hasegawa, Rei Takamiya, Sachiyo Iwata, Yasuko Mori
The evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has continued, enabling the virus to escape from host immunity by changing its spike antigen, while biased toward the receptor-binding domain and N-terminal domain. Here, we isolated a novel pan-SARS-CoV-2 neutralizing antibody (which we named MO11) for even the recent dominators XBB.1.16 and EG.5.1, from a convalescent patient who had received three doses of an original mRNA COVID-19 vaccination. A cryo-electron microscopy analysis of the spike-MO11 complex at 2...
April 16, 2024: Journal of Virology
#9
JOURNAL ARTICLE
D Salman, C Bolano-Diaz, R Muni-Lofra, K Wong, M Elseed, E Harris, J Diaz-Manera, M Guglieri, C Marini-Bettolo, V Straub, G Tasca
No abstract text is available yet for this article.
April 4, 2024: Neuromuscular Disorders: NMD
#10
JOURNAL ARTICLE
Loredana Vesci, Grazia Tundo, Sara Soldi, Serena Galletti, Daniela Stoppoloni, Roberta Bernardini, Anamaria Bianca Modolea, Laura Luberto, Emanuele Marra, Fabrizio Giorgi, Stefano Marini
Crohn's and ulcerative colitis are common conditions associated with inflammatory bowel disease as well as intestinal flora and epithelial barrier dysfunction. A novel fermented Lactobacillus brevis (AL0035) herein assayed in a trinitro benzene sulfonic acid (TNBS)-induced colitis mice model after oral administration significantly counteracted the body weight loss and improves the disease activity index and histological injury scores. AL0035 significantly decreased the mRNA and protein expression of different pro-inflammatory cytokines (TNFalpha, IL-1beta, IL-6, IL-12, IFN-gamma) and enhanced the expression of IL-10...
March 24, 2024: Nutrients
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JOURNAL ARTICLE
Federico Pio Fabrizio, Ilaria Attili, Filippo de Marinis
Uncommon (ucEGFRmuts) and rare epidermal growth factor receptor ( EGFR ) mutations account for 10-15% of diagnosed cases and consist of a heterogeneous group represented by several clusters within exons 18-21 (e.g., exon 18 point mutations, exon 21 L861X, exon 20 S768I), as well as exon 20 insertions (Ex20ins). Their incidence is under molecular and clinical investigation following recent findings that reported an increase of sensitivity and specificity of next-generation sequencing (NGS) methods. Consequently, their detection allows for the selection of emerging treatment options to significantly improve patients' outcomes in these particular subgroups of EGFR -mutated advanced non-small cell lung cancer (NSCLC)...
March 29, 2024: Cancers
#12
JOURNAL ARTICLE
Leonardo Belfioretti, Matteo Francioni, Ilaria Battistoni, Luca Angelini, Maria Vittoria Matassini, Giulia Pongetti, Matilda Shkoza, Luca Piangerelli, Tommaso Piva, Elisa Nicolini, Alessandro Maolo, Andi Muçaj, Paolo Compagnucci, Christopher Munch, Antonio Dello Russo, Marco Di Eusanio, Marco Marini
Background: The management of cardiogenic shock (CS) after ACS has evolved over time, and the development of a multidisciplinary team-based approach has been shown to improve outcomes, although mortality remains high. Methods: All consecutive patients with ACS-CS admitted at our CICU from March 2012 to July 2021 were included in this single-center retrospective study. In 2019, we established a "shock team" consisting of a cardiac intensivist, an interventional cardiologist, an anesthetist, and a cardiac surgeon...
April 3, 2024: Journal of Clinical Medicine
#13
REVIEW
Rebecca L Kummer, John J Marini
Acute respiratory distress syndrome (ARDS) is a well-defined clinical entity characterized by the acute onset of diffuse pulmonary injury and hypoxemia not explained by fluid overload. The COVID-19 pandemic brought about an unprecedented volume of patients with ARDS and challenged our understanding and clinical approach to treatment of this clinical syndrome. Unique to COVID-19 ARDS is the disruption and dysregulation of the pulmonary vascular compartment caused by the SARS-CoV-2 virus, which is a significant cause of hypoxemia in these patients...
March 22, 2024: Journal of Clinical Medicine
#14
JOURNAL ARTICLE
Ingridi Camboim Franceschi, Rubem Augusto da Paixão Dornas, Isabel Salgueiro Lermen, Artur Vicente Pfeifer Coelho, Ademir Henrique Vilas Boas, Adriano Garcia Chiarello, Adriano Pereira Paglia, Agnis Cristiane de Souza, Alana Rafaela Borsekowsky, Alessandro Rocha, Alex Bager, Alexander Zaidan de Souza, Alexandre Martins Costa Lopes, Aloysio Souza de Moura, Aluane Silva Ferreira, Alvaro García-Olaechea, Ana Cláudia Delciellos, Ana Elisa de Faria Bacellar, Ana Kellen Nogueira Campelo, Ana Maria Oliveira Paschoal, Anderson Claudino Rolim, André Luiz Ferreira da Silva, Andre Monnerat Lanna, André Pereira da Silva, Andresa Guimarães, Ângela Cardoso, Angelica Soligo Cassol, Anna Ludmilla da Costa-Pinto, Ariel Guilherme Santos do Nascimento, Arthur Soares Fernandes, Aryanne Clyvia, Aureo Banhos Dos Santos, Barbara Lima-Silva, Beatriz de Mello Beisiegel, Beatriz Fernandes Lima Luciano, Bernardo de Faria Leopoldo, Bruna Nunes Krobel, Bruno Busnello Kubiak, Bruno Henrique Saranholi, Bruno Senna Correa, Caio Sant Anna Teixeira, Camila Rezende Ayroza, Camila Righetto Cassano, Camilo Benitez-Riveros, Carla Cristina Gestich, Carla Denise Tedesco, Carla Gheler-Costa, Carla Grasiele Zanin Hegel, Carlito da Silva Evangelista Junior, Carlos Eduardo Morando Faria Ferreira, Carlos Eduardo Viveiros Grelle, Carolina Franco Esteves, Caroline da Costa Espinosa, Caroline Leuchtenberger, Catalina Sanchéz-Lalinde, Cauanne Iglesias Campos Machado, Cecilia Andreazzi, Cecília Bueno, Cecilia Cronemberger de Faria, Claudio Novaes, Cynthia Elisa Widmer, Cyntia Cavalcante Santos, Daniel da Silva Ferraz, Daniel Galiano, Daniela Aparecida Savariz Bôlla, Daniela Behs, Daniele Pereira Rodrigues, Danielle Picão de Melo, Déborah Maria Soares Ramos, Denise Lidório de Mattia, Diego Dias Pavei, Diogo Loretto, Douglas da Silva Huning, Douglas de Matos Dias, Éder Ricardo Paetzhold, Elaine Rios, Eleonore Zulnara Freire Setz, Eliana Cazetta, Emanuel Giovani Cafofo Silva, Emanuelle Pasa, Erica Naomi Saito, Erick Francisco Silva de Aguiar, Érika Paula Castro, Ernesto Bastos Viveiros de Castro, Ezequiel Pedó, Fabiane de Aguiar Pereira, Fábio Bolzan, Fábio de Oliveira Roque, Fábio Dias Mazim, Fábio Henrique Comin, Fábio Maffei, Felipe Bortolotto Peters, Felipe Moreli Fantacini, Felipe Pessoa da Silva, Felipe Santana Machado, Felipe Vélez-Garcia, Fernanda Stussi Duarte Lage, Fernando Araújo Perini, Fernando Camargo Passos, Fernando Carvalho, Fernando Cesar Cascelli de Azevedo, Fernando Ferreira, Fernando Ferreira de Pinho, Flávia Guimarães Chaves, Flavia Regina Miranda, Flavio Henrique Guimarães Rodrigues, Flávio Kulaif Ubaid, Francisco Homem Gabriel, Franco Leandro de Souza, Fred Victor de Oliveira, Gabriel Cupolillo, Gabriela de Araújo Pires Moreira, Gabriela Mette, Gabriela Teixeira Duarte, Gabrielle Beca, Gilberto Corso, Gilmar Perbiche-Neves, Glauber Henrique Borges de Oliveira Souto, Glenda Jéssica da Silva Vilarroel, Graziele O Batista, Guilherme Braga Ferreira, Gustavo Alves da Costa Toledo, Gustavo Senger, Helena de Godoy Bergallo, Hellen Cristina Pinheiro Dos Santos, Humberto Angelo Gazola, Isabel Melo, Ismael Verrastro Brack, Iuri Veríssimo, Ivan Réus Viana, Izabela Costa Laurentino, Jaime Luis Diehl, Jairo José Zocche, Jimi Martins-Silva, João Paulo Gava Just, Jorge José Cherem, Jorge Luiz Nascimento, Jorge Reppold Marinho, José Oliveira Dantas, Jose Roberto de Matos, José Salatiel Rodrigues Pires, Josi Fernanda Cerveira, Juan Ruiz-Esparza, Juliana Paulo da Silva, Juliano André Bogoni, Karina Theodoro Molina, Karla Dayane de Lima Pereira, Karoline Ceron, Kristel de Vleeschouwer, Laís Lautenschlager, Larissa Bailey, Larissa Fornitano, Lilian Elaine Rampim, Lorena Sforza, Luan Gonçalves Bissa, Luca Mattos Santucci, Lucas Gonçalves da Silva, Lucas Neves Perillo, Lucas Ribeiro Correa, Ludmila Hufnagel, Luis Fernando Alberti, Luis Jose Recalde Mello, Luis Renato Rezende Bernardo, Luiz Gustavo Rodrigues Oliveira-Santos, Luiza Neves Guimarães, Maíra Benchimol, Manuela Catharina Twardowschy, Marcela Ferreira-Riveros, Marcelo da Silva, Márcia Maria de Assis Jardim, Marco Aurélio Leite Fontes, Marcos Adriano Tortato, Marcos Tadeu do Nascimento, Margareth Lumy Sekiama, Maria Clara Nascimento-Costa, Maria Ester Bueno Dos Santos, Maria Santina de Castro Morini, Mariana Baldy Nagy-Reis, Mariane da Cruz Kaizer, Mariano José Ribeiro da Silva Sant'Anna, Marilia Teresinha Hartmann, Marina Ochoa Favarini, Marina Oliveira Olivo, Martín Alejandro Montes, Martin Roberto Del Valle Alvaréz, Matheus Feldstein Haddad, Maurício Djalles Costa, Maurício Eduardo Graipel, Mauricio Quoos Konzen, Mauro Galetti, Meyline de Oliveira Souza Almeida, Michel Barros Faria, Micheli Ribeiro Luiz, Michelle Noronha da Matta Baptista, Miguel Ângelo Marini, Milton Cezar Ribeiro, Natalie Olifiers, Natasha Moraes de Albuquerque, Nicolás Cantero, Nivaldo Peroni, Noeli Zanella, Olívia Mendonça-Furtado, Olivier Pays, Orlando Ednei Ferretti, Oscar Rocha-Barbosa, Paloma Marques Santos, Patrícia Menegaz de Farias, Patrício Adriano da Rocha, Paul François Colas-Rosas, Paula Ribeiro-Souza, Paula Ferracioli, Paulo Afonso Hartmann, Paulo de Tarso Zuquim Antas, Paulo Ribeiro, Paulo Tomasi Sarti, Paulo Ivo Mônico, Pedro Volkmer de Castilho, Peônia Brito de Moraes Pereira, Peter Gransden Crawshaw, Pierre-Cyril Renaud, Rafael Spilere Romagna, Rafael Turíbio Moraes de Sousa, Raíssa Soares Spagnol, Raone Beltrão-Mendes, Ravi Fernandes Mariano, Renata Reinoso Rocha, Renata Sousa-Lima, Renata Valls Pagotto, Rhayssa Terra de Faria, Ricardo Corassa Arrais, Ricardo Moratelli, Ricardo Sartorello, Rita de Cassia Bianchi, Roberto de Carvalho Guimarães, Rodrigo Lima Massara, Romulo Theodoro Costa, Rosane Vera Marques, Ruan Márcio Ruas Nunes, Sandra Maria Hartz, Saulo Meneses Silvestre de Sousa, Saulo Ramos Lima, Sergio Lutz Barbosa, Silvia Neri Godoy, Stephen Francis Ferrari, Talita Guimarães de Araújo-Piovezan, Talita Laura Góes, Tatiane Campos Trigo, Thales R O de Freitas, Thiago Bernardes Maccarini, Thiago Marcial de Castro, Thiago Ribas Bella, Tonny Marques de Oliveira Junior, Uslaine Maciel Cunha, Vanessa Tavares Kanaan, Vera Pfannerstill, Victor Siqueira Pimentel, Vilmar Picinatto Filho, Vinícius Nunes Alves, Viviana Rojas-Bonzi, Viviane Mottin, Vlamir José Rocha, Andreas Kindel, Igor Pfeifer Coelho
Camera traps became the main observational method of a myriad of species over large areas. Data sets from camera traps can be used to describe the patterns and monitor the occupancy, abundance, and richness of wildlife, essential information for conservation in times of rapid climate and land-cover changes. Habitat loss and poaching are responsible for historical population losses of mammals in the Atlantic Forest biodiversity hotspot, especially for medium to large-sized species. Here we present a data set from camera trap surveys of medium to large-sized native mammals (>1 kg) across the Atlantic Forest...
April 12, 2024: Ecology
#15
JOURNAL ARTICLE
Cell Membrane Fragment-Wrapped Parenteral Nanoemulsions: A New Drug Delivery Tool to Target Gliomas.
Chiara Dianzani, Annalisa Bozza, Valentina Bordano, Luigi Cangemi, Chiara Ferraris, Federica Foglietta, Chiara Monge, Margherita Gallicchio, Stefania Pizzimenti, Elisabetta Marini, Elisabetta Muntoni, Maria Carmen Valsania, Luigi Battaglia
Poor prognosis in high-grade gliomas is mainly due to fatal relapse after surgical resection in the absence of efficient chemotherapy, which is severely hampered by the blood-brain barrier. However, the leaky blood-brain-tumour barrier forms upon tumour growth and vascularization, allowing targeted nanocarrier-mediated drug delivery. The homotypic targeting ability of cell-membrane fragments obtained from cancer cells means that these fragments can be exploited to this aim. In this experimental work, injectable nanoemulsions, which have a long history of safe clinic usage, have been wrapped in glioma-cell membrane fragments via co-extrusion to give targeted, homogeneously sized, sterile formulations...
April 6, 2024: Cells
#16
JOURNAL ARTICLE
Claude Lambré, José Manuel Barat Baviera, Claudia Bolognesi, Pier Sandro Cocconcelli, Riccardo Crebelli, David Michael Gott, Konrad Grob, Evgenia Lampi, Marcel Mengelers, Alicja Mortensen, Gilles Rivière, Inger-Lise Steffensen, Christina Tlustos, Henk Van Loveren, Laurence Vernis, Yrjö Roos, Yi Liu, Eleonora Marini, Giulio di Piazza, Andrew Chesson
The food enzyme peroxidase (phenolic donor: hydrogen-peroxide oxidoreductase, EC 1.11.1.7) is produced with the genetically modified Aspergillus niger strain MOX by DSM Food Specialties B.V. A safety evaluation of this food enzyme was made previously, in which EFSA concluded that this food enzyme did not give rise to safety concerns when used in one food manufacturing process. Subsequently, the applicant requested to extend its use to include an additional process. In this assessment, EFSA updated the safety evaluation of this food enzyme when used in a total of two food manufacturing processes: processing of dairy products for the production of modified milk proteins and the production of plant-based analogues of milk and milk products...
April 2024: EFSA journal
#17
JOURNAL ARTICLE
Claude Lambré, José Manuel Barat Baviera, Claudia Bolognesi, Pier Sandro Cocconcelli, Riccardo Crebelli, David Michael Gott, Konrad Grob, Evgenia Lampi, Marcel Mengelers, Alicja Mortensen, Gilles Rivière, Inger-Lise Steffensen, Christina Tlustos, Henk Van Loveren, Laurence Vernis, Holger Zorn, Yrjö Roos, Yi Liu, Eleonora Marini, Giulio di Piazza, Andrew Chesson
The food enzyme triacylglycerol lipase (triacylglycerol acylhydrolase, EC 3.1.1.3) is produced with the non-genetically modified Mucor circinelloides strain AE-LMH by Amano Enzyme Inc. A safety evaluation of this food enzyme was made previously, in which EFSA concluded that this food enzyme did not give rise to safety concerns when used in three food manufacturing processes. Subsequently, the applicant requested to extend its use to include two additional processes. In this assessment, EFSA updated the safety evaluation of this food enzyme when used in a total of five food manufacturing processes...
April 2024: EFSA journal
#18
JOURNAL ARTICLE
Claude Lambré, José Manuel Barat Baviera, Claudia Bolognesi, Pier Sandro Cocconcelli, Riccardo Crebelli, David Michael Gott, Konrad Grob, Evgenia Lampi, Marcel Mengelers, Alicja Mortensen, Gilles Rivière, Inger-Lise Steffensen, Christina Tlustos, Henk Van Loveren, Laurence Vernis, Holger Zorn, Yrjö Roos, Yi Liu, Eleonora Marini, Giulio di Piazza, Andrew Chesson
The food enzyme α -glucosidase ( α -d-glucoside glucohydrolase; EC 3.2.1.20) is produced with the non-genetically modified Aspergillus niger strain AE-TGU by Amano Enzyme Inc. A safety evaluation of this food enzyme was made previously, in which EFSA concluded that this food enzyme did not give rise to safety concerns when used in four food manufacturing processes. Subsequently, the applicant requested to extend its use to include three additional processes. In this assessment, EFSA updated the safety evaluation of this food enzyme when used in a total of seven food manufacturing processes...
April 2024: EFSA journal
#19
RANDOMIZED CONTROLLED TRIAL
Yi-Long Wu, Rafal Dziadziuszko, Jin Seok Ahn, Fabrice Barlesi, Makoto Nishio, Dae Ho Lee, Jong-Seok Lee, Wenzhao Zhong, Hidehito Horinouchi, Weimin Mao, Maximilian Hochmair, Filippo de Marinis, M Rita Migliorino, Igor Bondarenko, Shun Lu, Qun Wang, Tania Ochi Lohmann, Tingting Xu, Andres Cardona, Thorsten Ruf, Johannes Noe, Benjamin J Solomon
BACKGROUND: Platinum-based chemotherapy is the recommended adjuvant treatment for patients with resectable, ALK -positive non-small-cell lung cancer (NSCLC). Data on the efficacy and safety of adjuvant alectinib as compared with chemotherapy in patients with resected ALK -positive NSCLC are lacking. METHODS: We conducted a global, phase 3, open-label, randomized trial in which patients with completely resected, ALK -positive NSCLC of stage IB (tumors ≥4 cm), II, or IIIA (as classified according to the seventh edition of the Cancer Staging Manual of the American Joint Committee on Cancer and Union for International Cancer Control) were randomly assigned in a 1:1 ratio to receive oral alectinib (600 mg twice daily) for 24 months or intravenous platinum-based chemotherapy in four 21-day cycles...
April 11, 2024: New England Journal of Medicine
#20
JOURNAL ARTICLE
James A Fowler, Marini Mendis, Alex Crook, UnYoung Chavez-Baldini, Tabitha Baca, Judith A Dean
OBJECTIVE: To explore what aromanticism is, common misconceptions about this identity, and the experiences people have connecting with an aromantic identity. METHODS: An online, international open-ended survey with a convenience sample of aromantic individuals ( N = 1642) analyzed with thematic analysis. RESULTS: To identify as aromantic involves a spectrum of experiences with romance commonly tied to experiencing stigma. Connecting with an aromantic identity allows for a greater understanding of the self and a connection to a community...
2024: International Journal of Sexual Health
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