keyword
MENU ▼
Read by QxMD icon Read
search

Photoaging

keyword
https://www.readbyqxmd.com/read/29330857/reduction-of-hyaluronan-and-increased-expression-of-hybid-kiaa1199-correlate-with-clinical-symptoms-in-photoaged-skin
#1
H Yoshida, A Nagaoka, A Komiya, M Aoki, S Nakamura, T Morikawa, R Ohtsuki, T Sayo, Y Okada, Y Takahashi
BACKGROUND: Hyaluronan (HA) metabolism in skin fibroblasts is mediated by HYBID (HYaluronan Binding protein Involved in hyaluronan Depolymerisation, KIAA1199) and HA synthases 1/2 (HAS1/2). However, photoageing-dependent changes in HA and their molecular mechanisms, and the relationship between HA metabolism and clinical symptoms in photoaged skin remain elusive. OBJECTIVES: We examined amount, size and tissue distribution of HA and expression levels of HYBID and HAS1/2 in photoaged skin, and analysed their relationships to the degree of photoageing...
January 12, 2018: British Journal of Dermatology
https://www.readbyqxmd.com/read/29320590/treatment-of-d%C3%A3-colletage-photoaging-with-fractional-microneedling-radiofrequency
#2
Alexis Lyons, Jillian Roy, Jennifer Herrmann, Lisa Chipps
OBJECTIVES: The objective of this study was to examine the efficacy and safety of a novel fractional microneedling radiofrequency device to improve the appearance of rhytides and skin laxity of the décolletage. METHODS: Twelve subjects received a total of three fractional microneedling radiofrequency treatments with Endymed Intensif (EndyMed Ltd., Cesarea, Israel) at least three weeks apart. Primary outcome measure was clinical efficacy quantified by a patient survey to assess treatment satisfaction as well as a physician Global Aesthetic Improvement Scale (GAIS)...
January 1, 2018: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/29320586/safety-and-efficacy-of-a-1550nm-1927nm-dual-wavelength-laser-for-the-treatment-of-photodamaged-skin
#3
Vic A Narurkar, Tina S Alster, Eric F Bernstein, Tina J Lin, Anya Loncaric
<p>BACKGROUND: Fractional photothermolysis (FP) is a popular treatment option for photodamaged skin and addresses shortcomings of ablative skin resurfacing and nonablative dermal remodeling. Previous studies have demonstrated that FP using the 1550nm wavelength has led to improvement of ultrastructural changes and clinical effects associated with photodamaged skin in the deeper dermal structures, while treatment with the 1927nm wavelength has shown clinical effects in the superficial dermis. Both wavelengths produce precise microscopic treatment zones (MTZs) in the skin...
January 1, 2018: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/29317425/correction-a-smoking-prevention-photoageing-intervention-for-secondary-schools-in-brazil-delivered-by-medical-students-protocol-for-a-randomised-trial
#4
(no author information available yet)
No abstract text is available yet for this article.
January 9, 2018: BMJ Open
https://www.readbyqxmd.com/read/29309339/punctuated-88-phenol-peeling-for-the-treatment-of-facial-photoaging-a-clinical-and-histopathological-study
#5
Maria Cristina C de Mendonça, Natália N Segheto, Fernando M Aarestrup, Beatriz J V Aarestrup
BACKGROUND: Phenol peeling is considered an important agent in the treatment of facial rejuvenation; however, its use has limitations due to its high potential for side effects. OBJECTIVE: This article proposes a new peeling application technique for the treatment of photoaging, aiming to evaluate, clinically and histopathologically, the efficacy of a new way of applying 88% phenol, using a punctuated pattern. METHODS: The procedure was performed in an outpatient setting, with female patients, on static wrinkles and high flaccidity areas of the face...
January 5, 2018: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/29307270/rice-bran-supplement-prevents-uvb-induced-skin-photoaging-in-vivo
#6
Su Jeong Ha, Joon Park, Jangho Lee, Kyung-Mo Song, Min Young Um, Suengmok Cho, Sung Keun Jung
Although rice bran consumption is reportedly has numerous beneficial effects on human health, the relationship between rice bran and the prevention of photoaging has not been investigated in detail. We sought to investigate whether consumption of rice bran supplement (RBS) can elicit preventive effects against UVB-induced photoaging in vivo. Dorsal skin sections of hairless mice were exposed to UVB over 16 weeks. RBS consumption suppressed UVB-induced wrinkle formation and inhibited the loss of water content and epidermal thickening in the mouse skin...
January 8, 2018: Bioscience, Biotechnology, and Biochemistry
https://www.readbyqxmd.com/read/29296569/effect-of-thread-embedding-acupuncture-for-facial-wrinkles-and-laxity-a-single-arm-prospective-open-label-study
#7
Younghee Yun, Inhwa Choi
Background: There is a growing trend for patients to seek the least invasive treatments with less risk of complications and downtime for facial rejuvenation. Thread embedding acupuncture has become popular as a minimally invasive treatment. However, there is little clinical evidence in the literature regarding its effects. Methods: This single-arm, prospective, open-label study recruited participants who were women aged 40-59 years, with Glogau photoaging scale III-IV...
December 2017: Integrative Medicine Research
https://www.readbyqxmd.com/read/29295735/photodynamic-therapy-interventions-in-facial-photodamage-a-systematic-review
#8
G Sanclemente, V Ruiz-Cañas, J M Miranda, A P Ferrín, P A Ramirez, G N Hernandez
INTRODUCTION: Photodynamic therapy (PDT) involves the combination of a light source and a photosensitizing agent to induce tissue damage via the generation of singlet oxygen. Although topical PDT has been approved for other indications, its use in facial photodamage is uncertain. AIMS: To assess the efficacy and safety of PDT in facial skin photoaging. METHODS: All randomized clinical trials (RCTs) evaluating the efficacy and safety of any form of topical PDT for the treatment of facial photodamage (dermatoheliosis) or photoaging in patients older than 18 years, were included...
December 30, 2017: Actas Dermo-sifiliográficas
https://www.readbyqxmd.com/read/29287765/mechanisms-of-aging-and-development-a-new-understanding-of-environmental-damage-to-the-skin-and-prevention-with-topical-antioxidants
#9
REVIEW
Karen E Burke
Recent research has given us new insights into the molecular biology of extrinsic aging of the skin. Not only does UV irradiation directly cause photoaging of the skin, but also environmental pollutants significantly damage exposed skin by several mechanisms. Exposure to the noxious gases of air pollution with simultaneous exposure to UVA can act synergistically to initiate skin cancer. Also ozone generated from pollutants reacting with UV induces oxidative stress of the skin's surface via formation of lipid peroxidation products, with cascading consequences to deeper layers...
December 26, 2017: Mechanisms of Ageing and Development
https://www.readbyqxmd.com/read/29285880/melasma-a-photoaging-disorder
#10
REVIEW
Thierry Passeron, Mauro Picardo
Melasma is a common hyperpigmentary disorder. The impact on the quality of life of affected individuals is well demonstrated, demanding new therapeutic strategies. However, the treatment of melasma remains highly challenging. Melasma is often considered as the main consequence of female hormone stimulation on a predisposed genetic background. Although these two factors do contribute to this acquired pigmentary disorder, the last decade has revealed several other key players and brought new pieces to the complex puzzle of the pathophysiology of melasma...
December 29, 2017: Pigment Cell & Melanoma Research
https://www.readbyqxmd.com/read/29275159/anti-photoaging-effects-of-chitosan-oligosaccharide-in-ultraviolet-irradiated-hairless-mouse-skin
#11
Song-Zhi Kong, Dong-Dong Li, Hui Luo, Wen-Jie Li, Yong-Mei Huang, Ji-Cheng Li, Zhang Hu, Na Huang, Min-Hui Guo, Yao Chen, Si-Dong Li
Skin photoaging (SP) is a premature skin-aging damage after repeated exposure to ultraviolet (UV) radiation, mainly characterized by oxidative stress and inflammatory disequilibrium, which makes skin show the typical symptoms of photoaging such as coarse wrinkling, dryness, irregular pigmentation and laxity. Chitosan oligosaccharide (COS), a natural polysaccharide with good humectant property, is the depolymerized product of chitosan with various biological activities, among which the antioxidant and anti-inflammatory effects have been frequently reported in recent years...
December 21, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/29273513/zerumbone-protects-human-skin-keratinocytes-against-uva-irradiated-damages-through-nrf2-induction
#12
Hsin-Ling Yang, Chin-Ling Lee, Mallikarjuna Korivi, Jiunn-Wang Liao, Peramaiyan Rajendran, Jia-Jiuan Wu, You-Cheng Hseu
Ultraviolet A (UVA) irradiation is toxic to skin as it penetrates deep into the dermis and damages cellular components through excessive reactive oxygen species (ROS) production, which accelerates photoaging and skin cancer. We evaluated the dermato-protective efficacies of zerumbone (natural sesquiterpene of Zingiber zerumbet) in UVA-irradiated human skin keratinocyte (HaCaT) cells and mouse epidermis. Zerumbone pretreatment (2-10 μM) substantially suppressed UVA (15 J/cm2)-induced HaCaT cell death and lactate dehydrogenase release in a dose-dependent manner...
December 19, 2017: Biochemical Pharmacology
https://www.readbyqxmd.com/read/29272917/purification-and-characterization-of-peptides-inhibiting-mmp-1-activity-with-c-terminate-of-gly-leu-from-simulated-gastrointestinal-digestion-hydrolysates-of-tilapia-oreochromis-niloticus-skin-gelatin
#13
Sun Liping, Liu Qiuming, Fan Jian, Li Xiao, Zhuang Yongliang
Tilapia skin gelatin hydrolysates (TSGH) were prepared by simulated gastrointestinal digestion and separated by gel filtration and semipreparative reverse phase-high performance liquid chromatography. The antiphotoaging effects were evaluated using an ultraviolet radiation B (UVB)-induced mouse embryonic fibroblasts (MEFs) photoaging model in vitro. Three fractions from TSGH with high inhibitory intercellular matrix metalloproteinases-1 (MMP-1) activities and reactive oxygen species (ROS) production were obtained...
December 22, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29250823/transcriptome-analysis-of-ultraviolet-a-induced-photoaging-cells-with-deep-sequencing
#14
Yue Zheng, Qingfang Xu, Haiyan Chen, Qiaoping Chen, Zijian Gong, Wei Lai
Gene expression changes associate with many biological processes. However, the relative consequences of the genetic alterations induced by ultraviolet (UV)-A radiation on skin photoaging are still not clear. Here, we performed deep sequencing of the transcriptome and explored altered genes related to biological changes in repeated UV-A-irradiated human dermal fibroblasts (HDF) to better understand the skin photoaging mechanisms. The repeatedly UV-A-irradiated group (HDF were induced by 10 J/cm2 UV-A twice daily for 7 days) and the control group (HDF without irradiation) were evaluated...
December 18, 2017: Journal of Dermatology
https://www.readbyqxmd.com/read/29235191/the-effect-of-cyanidin-3-o-glucoside-on-uva-induced-damage-in-human-dermal-fibroblasts
#15
Shi Wu, Yunfeng Hu, Zhen Li, Weibin Bai, Jiayi Zhao, Cuiqin Huang, Qin Li, Chongzhu Fan, Liehua Deng, Daxiang Lu
BACKGROUND/PURPOSE: Ultraviolet-A (UVA) radiation can induce photoaging and skin cancer, but means to prevent or treat UVA-induced skin damage require further study. We investigated the effects of cyanidin-3-o-glucoside (C3G), a monomer of anthocyanin, on UVA-induced damage in primary human dermal fibroblasts (HDFs), and we identify possible mechanisms underlying the protective effects of this compound. METHODS: Primary HDFs were pretreated with 80 μM C3G for 2 h and UVA irradiated at 12 J/cm2 ...
December 13, 2017: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/29229659/a-smoking-prevention-photoageing-intervention-for-secondary-schools-in-brazil-delivered-by-medical-students-protocol-for-a-randomised-trial
#16
Bianca Lisa Faria, Christian M Brieske, Ioana Cosgarea, Albert J Omlor, Fabian N Fries, Christian Olber Moreira de Faria, Henrique Augusto Lino, Ana Carla Cruz Oliveira, Oscar Campos Lisboa, Joachim Klode, Dirk Schadendorf, Breno Bernardes-Souza, Titus J Brinker
INTRODUCTION: Most smokers start smoking during their early adolescence, often with the idea that smoking is glamorous; the dramatic health consequences are too far in the future to fathom. We recently designed and tested an intervention that takes advantage of the broad availability of mobile phones as well as adolescents' interest in their appearance. A free photoageing mobile app (Smokerface) was implemented by medical students in secondary schools via a novel method called mirroring...
December 10, 2017: BMJ Open
https://www.readbyqxmd.com/read/29228428/inhibition-of-mmps-cat-g-and-downregulates-the-signaling-of-tgf-%C3%AE-smad-in-chronic-photodamaged-human-fibroblasts
#17
Y Zheng, Q-F Xu, H-Y Chen, C-X Ye, W Lai, H I Maibach
OBJECTIVE: To understand the action of Cathepsin G (Cat G) and matrix metalloproteases (MMPs) on the β/Smad pathway of transforming growth factor β (TGF-β) in chronically photodamaged human fibroblasts. Cat G plays a significant role in the process of skin photoaging and in collagen synthesis and degradation which is induced by UV irradiation it could interact with TGF-β/Smad signaling. No available studies have thoroughly explored its molecular mechanisms of photoaging regulation...
November 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29197123/what-is-the-role-of-mitochondrial-dysfunction-in-skin-photoageing
#18
Khimara Naidoo, Rebecca Hanna, Mark A Birch-Machin
Skin ageing is a complex process involving both internal and external factors, which leads to a progressive loss of cutaneous function and structure. Solar radiation is the primary environmental factor implicated in the development of skin ageing and the term photoageing describes the distinct clinical, histological and structural features of chronically sun-exposed skin. The changes that accompany photoageing are undesirable for aesthetic reasons and can compromise the skin and make it more susceptible to a number of dermatological disorders...
December 2, 2017: Experimental Dermatology
https://www.readbyqxmd.com/read/29191355/clinical-and-prognostic-factors-in-the-development-of-basal-cell-carcinoma
#19
Sevil Savas, Aslı V Turgut Erdemir, Ayse E Koku Aksu, Mehmet S Gurel, Ezgi Ozkur
We investigated the environmental and personal risk factors associated with the development of basal cell carcinoma (BCC). This retrospective cohort study included a total of 997 patients whose diagnosis was confirmed by histopathologic examination between 2007 and 2014. A control examination was performed in 363 of these patients, who were accessed via telephone. A total of 1151 tumors were detected in 997 patients. During their follow-up, 13% of them developed subsequent tumors. The risk of developing subsequent tumor was 2...
November 2017: Clinics in Dermatology
https://www.readbyqxmd.com/read/29189718/elucidating-the-skin-delivery-of-aglycone-and-glycoside-flavonoids-how-the-structures-affect-cutaneous-absorption
#20
Shih-Yi Chuang, Yin-Ku Lin, Chwan-Fwu Lin, Pei-Wen Wang, En-Li Chen, Jia-You Fang
Flavonoids are bioactive phytochemicals that exhibit protective potential against cutaneous inflammation and photoaging. We selected eight flavonoid aglycones or glycosides to elucidate the chemistry behind their skin absorption capability through experimental and computational approaches. The skin delivery was conducted using nude mouse and pig skins mounted on an in vitro Franz cell assembly. The anti-inflammatory activity was examined using the O₂•.
November 30, 2017: Nutrients
keyword
keyword
744
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"