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https://www.readbyqxmd.com/read/27910817/on-the-molecular-interaction-between-femoral-heads-and-polyethylene-liners-in-artificial-hip-joints-phenomenology-and-molecular-scale-phenomena
#1
Giuseppe Pezzotti, B Sonny Bal, Elisa Casagrande, Nobuhiko Sugano, Bryan J McEntire, Wenliang Zhu, Leonardo Puppulin
The chemical interaction of femoral heads with polyethylene liners is an important new area of research in total hip arthroplasty (THA) as a consequence of an unabating quest for elongated artificial joint lifetimes. It is a topic that goes beyond simple mechanical behavior or wear. It seeks to describe the prosthetic device as a whole by adding chemical considerations to mechanics and abrasion. One of the poorly understood chemical interactions is oxygen affinity of the femoral heads. While oxygen unavoidably diffuses into the non-crystalline enclaves of the polyethylene liner as a result of its contact with the tribolayer, a ceramic femoral head can either attract or release oxygen due to its tribochemical interactions...
December 2, 2016: Biomedical Materials
https://www.readbyqxmd.com/read/27909903/obesity-and-kidney-cancer
#2
Kathryn M Wilson, Eunyoung Cho
Renal cell cancer (RCC) is the major type of kidney cancer with increasing incidence. Obesity is one of the well-established risk factors for RCC. Meta-analyses including multiple cohort and case-control studies have found a consistent positive association between obesity and RCC. The association appeared to be independent of other RCC risk factors including hypertension and has been often stronger in women, although a positive association has also been observed in men. Obesity has been largely measured as body mass index (BMI)...
2016: Recent Results in Cancer Research
https://www.readbyqxmd.com/read/27909900/obesity-and-colorectal-cancer
#3
Carmen Jochem, Michael Leitzmann
There is strong evidence that modifiable lifestyle factors such as obesity play a key role in colorectal carcinogenesis. Epidemiologic data have consistently reported a positive association between obesity and colorectal cancer. The relative risk associated with general obesity (as assessed by BMI) is higher in men than in women and for cancer of the colon than for cancer of the rectum. Abdominal obesity (as assessed by waist circumference (WC) or waist-to-hip ratio) is associated with an increased risk of colorectal cancer in both sexes, with stronger associations for cancer of the colon than for cancer of the rectum...
2016: Recent Results in Cancer Research
https://www.readbyqxmd.com/read/27909663/the-quebec-city-slider-a-technique-for-capsular-closure-and-plication-in-hip-arthroscopy
#4
Travis J Menge, Jorge Chahla, Eduardo Soares, Justin J Mitchell, Marc J Philippon
Biomechanical and clinical studies have shown that the hip joint capsule plays an important role in maintaining stability and hip mechanics, including rotation and translation. The recent literature has shown that capsule closure after hip arthroscopy helps to restore stability. Without restoration of the native anatomy, the hip joint may translate when patients engage in activities that place force across the hip, leading to either microinstability or frank dislocation. The purpose of this note is to describe our preferred technique of capsular closure or plication during hip arthroscopy...
October 2016: Arthroscopy Techniques
https://www.readbyqxmd.com/read/27907000/whole-body-vibration-treatments-in-postmenopausal-women-can-improve-bone-mineral-density-results-of-a-stimulus-focussed-meta-analysis
#5
Antonio Fratini, Tecla Bonci, Anthony M J Bull
Whole body vibration treatment is a non-pharmacological intervention intended to stimulate muscular response and increase bone mineral density, particularly for postmenopausal women. The literature related to this topic is controversial, heterogeneous, and unclear despite the prospect of a major clinical effect.The aim of this study was to identify and systematically review the literature to assess the effect of whole body vibration treatments on bone mineral density (BMD) in postmenopausal women with a specific focus on the experimental factors that influence the stimulus...
2016: PloS One
https://www.readbyqxmd.com/read/27906085/tissue-engineered-cardiac-patch-seeded-with-human-induced-pluripotent-stem-cell-derived-cardiomyocytes-promoted-the-regeneration-of-host-cardiomyocytes-in-a-rat-model
#6
Tadahisa Sugiura, Narutoshi Hibino, Christopher K Breuer, Toshiharu Shinoka
BACKGROUND: Thousands of babies are born with congenital heart defects that require surgical repair involving a prosthetic implant. Lack of growth in prosthetic grafts is especially detrimental in pediatric surgery. Cell seeded biodegradable tissue engineered grafts are a novel solution to this problem. The purpose of the present study is to evaluate the feasibility of seeding human induced pluripotent stem cell derived cardiomyocytes (hiPS-CMs) onto a biodegradable cardiac patch. METHODS: The hiPS-CMs were cultured on a biodegradable patch composed of a polyglycolic acid (PGA) and a 50:50 poly (l-lactic-co-ε-caprolactone) copolymer (PLCL) for 1 week...
December 1, 2016: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/27904792/current-concepts-and-treatment-of-patellofemoral-compressive-issues
#7
Michael J Mullaney, Takumi Fukunaga
Patellofemoral disorders, commonly encountered in sports and orthopedic rehabilitation settings, may result from dysfunction in patellofemoral joint compression. Osseous and soft tissue factors, as well as the mechanical interaction of the two, contribute to increased patellofemoral compression and pain. Treatment of patellofemoral compressive issues is based on identification of contributory impairments. Use of reliable tests and measures is essential in detecting impairments in hip flexor, quadriceps, iliotibial band, hamstrings, and gastrocnemius flexibility, as well as in joint mobility, myofascial restrictions, and proximal muscle weakness...
December 2016: International Journal of Sports Physical Therapy
https://www.readbyqxmd.com/read/27896394/the-orientation-of-the-surgical-epicondylar-axis-varies-in-varus-and-non-varus-knees-in-the-coronal-plane
#8
Yunjie Zhang, Xiaofeng Wang, Yunchao Shao, Qing Xia
PURPOSE: To investigate the orientations of the surgical epicondylar axis (SEA) of varus and non-varus knees in the coronal plane. METHODS: One-hundred and sixty-two knees from 81 Chinese patients undergoing total knee arthroplasty (TKA) were retrospectively investigated. The angle between the medial side of the femoral mechanical axis and the SEA (MA-SEA), as well as the physiological valgus angle, was measured in the coronal plane using three-dimensional reconstruction...
November 28, 2016: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/27896294/a-qualitative-assessment-of-return-to-sport-after-hip-arthroscopy-for-femoroacetabular-impingement
#9
Vehniah K Tjong, Charles J Cogan, Brett D Riederman, Michael A Terry
BACKGROUND: Hip arthroscopy for femoroacetabular impingement (FAI) is known to produce excellent outcomes, yet some patients do not return to their preinjury level of sport participation. Much literature on return to sport has revolved around anterior cruciate ligament reconstruction and even shoulder instability, but none to date have used qualitative, semistructured patient interviews on patients with hip labral tears. PURPOSE: To understand the factors influencing the decision to return to sport after arthroscopic hip surgery for FAI...
November 2016: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/27892748/are-porous-tantalum-cups-superior-to-conventional-reinforcement-rings
#10
Anders Brüggemann, Erik Fredlund, Hans Mallmin, Nils P Hailer
Background and purpose - Porous tantalum cups have been introduced as an alternative to various reinforcement rings in revision hip surgery. We hypothesized that porous tantalum cups would be superior to Müller acetabular roof reinforcement rings (MARRs) in revision hip surgery with re-revision for aseptic loosening as the primary outcome measure. Patients and methods - 207 hips operated with either a porous tantalum cup (TM cup, n = 111) or a MARR (n = 96) at index procedure were identified in our local arthroplasty register...
November 28, 2016: Acta Orthopaedica
https://www.readbyqxmd.com/read/27892564/zirconia-based-dental-ceramics-structure-mechanical-properties-biocompatibility-and-applications
#11
Chandkiram Gautam, Jarin Joyner, Amarendra Gautam, Jitendra Rao, Robert Vajtai
Zirconia (ZrO2) based dental ceramics have been considered to be advantageous materials with adequate mechanical properties for the manufacturing of medical devices. Due to its very high compression strength of 2000 MPa, ZrO2 can resist differing mechanical environments. During the crack propagation on the application of stress on the surface of ZrO2, a crystalline modification diminishes the propagation of cracks. In addition, zirconia's biocompatibility has been studied in vivo, leading to the observation of no adverse response upon the insertion of ZrO2 samples into the bone or muscle...
November 28, 2016: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/27890623/sirt1-protects-osteoblasts-against-particle-induced-inflammatory-responses-and-apoptosis-in-aseptic-prosthesis-loosening
#12
Zhantao Deng, Zhenheng Wang, Jiewen Jin, Yong Wang, Nirong Bao, Qian Gao, Jianning Zhao
: We hypothesized that SIRT1 downregulation in osteoblasts induced by wear particles was one of the reasons for particle-induced osteolysis (PIO) in total joint arthroplasty failure. In the present study, the expression of SIRT1 was examined in osteoblasts treated with TiAl6V4 particles (TiPs) and CoCrMo particles (CoPs) from materials used in prosthetics and specimens from PIO animal models. To address whether SIRT1 downregulation triggers inflammatory responses and apoptosis in osteoblasts, the effect of a SIRT1 activator, resveratrol on the expression of inflammatory cytokines and apoptosis in particle-treated osteoblasts was tested...
November 23, 2016: Acta Biomaterialia
https://www.readbyqxmd.com/read/27889840/five-to-thirteen-year-results-of-a-cemented-dual-mobility-socket-to-treat-recurrent-dislocation
#13
Moussa Hamadouche, Mickael Ropars, Camille Rodaix, Thierry Musset, François Gaucher, David Biau, Jean Pierre Courpied, Denis Huten
PURPOSE: Dual mobility (DM) socket has been associated with a low rate of dislocation following both primary and revision total hip arthroplasty (THA). However, little is known about the long-term efficiency of DM in the treatment of THA instability. The purpose of this retrospective study was to evaluate the outcome of a cemented DM socket to treat recurrent dislocation after a minimum of five year follow-up. METHODS: The series included 51 patients with a mean age of 71...
November 26, 2016: International Orthopaedics
https://www.readbyqxmd.com/read/27886360/high-proximal-migration-in-cemented-acetabular-revisions-operated-with-bone-impaction-grafting-47-revision-cups-followed-with-rsa-for-17-years
#14
Maziar Mohaddes, Peter Herberts, Henrik Malchau, Per-Erik Johanson, Johan Kärrholm
BACKGROUND: Bone impaction grafting is a biologically and mechanically appealing option in acetabular revision surgery, allowing restitution of the bone stock and restoration of the biomechanics. We analysed differences in proximal migration of the revision acetabular components when bone impaction grafting is used together with a cemented or an uncemented cup. PATIENTS AND METHODS: 43 patients (47 hips), revised due to acetabular loosening and judged to have less than 50% host bone-implant contact were included...
November 22, 2016: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/27881118/electrolyte-disorders-and-aging-risk-factors-for-delirium-in-patients-undergoing-orthopedic-surgeries
#15
Li-Hong Wang, Dong-Juan Xu, Xian-Jiao Wei, Hao-Teng Chang, Guo-Hong Xu
BACKGROUND: At present, the exact mechanism of postoperative delirium has not been elucidated. The purpose of this study was to analyze the incidence of delirium in patients undergoing orthopedic surgeries and to explore possible related factors. METHODS: This is a retrospective study. We used 582 patients who had undergone orthopedic surgery between January 2011 and December 2014. The surgeries consisted of 155 cases of internal fixation for intertrochanteric fracture (IFIF), 128 cases of femoral head replacement (FHR), 169 cases of total hip arthroplasty (THA) and 130 cases of total knee arthroplasty (TKA)...
November 23, 2016: BMC Psychiatry
https://www.readbyqxmd.com/read/27876489/morphologic-changes-and-outcomes-after-arthroscopic-acetabular-labral-repair-evaluated-using-postoperative-computed-tomography-arthrography
#16
Jun-Il Yoo, Yong-Chan Ha, Young-Kyun Lee, Guen-Young Lee, Moon-Jib Yoo, Kyung-Hoi Koo
PURPOSE: To investigate smaller sized labra after acetabular labral repair comparing preoperative and postoperative computed tomography arthrography (CTA) and to assess the correlation between the anatomic changes and clinical outcomes. METHODS: The design and protocol of this retrospective study were approved by the institutional review board of our hospital. The inclusion criteria included age older than 18 years and hip pain associated with mechanical symptoms...
November 19, 2016: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/27876256/do-changes-in-the-production-process-affect-the-outcome-of-ceramic-liners-a-3-year-follow-up-study
#17
Tom Schmidt-Braekling, Lisa Renner, Douglas N Mintz, Wenzel Waldstein, Yoshimi Endo, Friedrich Boettner
BACKGROUND: In 2011, the current liner was withdrawn from the market because of the potential risk for liner fracture secondary to increased pressures used to assemble the metal locking ring. The present study provides a short-term follow-up of patients with this implant. METHODS: We retrospectively evaluated 63 consecutive hips in 53 patients operated by a single surgeon using a recalled ceramic-on-ceramic bearing. There were 30 women and 23 men with an average age of 50...
October 20, 2016: Journal of Arthroplasty
https://www.readbyqxmd.com/read/27876030/long-term-outcomes-following-lower-extremity-press-fit-bone-anchored-prosthesis-surgery-a-5-year-longitudinal-study-protocol
#18
Ruud A Leijendekkers, J Bart Staal, Gerben van Hinte, Jan Paul Frölke, Hendrik van de Meent, Femke Atsma, Maria W G Nijhuis-van der Sanden, Thomas J Hoogeboom
BACKGROUND: Patients with lower extremity amputation frequently suffer from socket-related problems. This seriously limits prosthesis use, level of activity and health-related quality of life (HRQoL). An additional problem in patients with lower extremity amputation are asymmetries in gait kinematics possibly accounting for back pain. Bone-anchored prostheses (BAPs) are a possible solution for socket-related problems. Knowledge concerning the level of function, activity and HRQoL after surgery is limited...
November 22, 2016: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/27872981/dual-mobility-arthroplasty-failure-a-rationale-review-of-causes-and-technical-considerations-for-revision
#19
Philippe Hernigou, Arnaud Dubory, Damien Potage, François Roubineau, Charles Henri Flouzat Lachaniette
PURPOSE: Dual-mobility arthroplasty is an alternative to conventional total hip arthroplasty (THA) in appropriately selected, active adults with degenerative, necrotic or post-traumatic hip disease or with revision hip arthroplasty. Numerous papers have been published with results of dual-mobility arthroplasty, but there have been no comprehensive literature reviews that summarise the most recent findings and help the orthopaedic surgeon facing different scenarios in which revision of one or both components of a dual-mobility arthroplasty is indicated...
November 21, 2016: International Orthopaedics
https://www.readbyqxmd.com/read/27870648/facilitated-temporal-summation-of-pain-correlates-with-clinical-pain-intensity-after-hip-arthroplasty
#20
Masashi Izumi, Kristian Kjær Petersen, Mogens Berg Laursen, Lars Arendt-Nielsen, Thomas Graven-Nielsen
Widespread hyperalgesia has been found in patients with painful hip osteoarthritis (OA) which can be normalized after total hip arthroplasty (THA) if patients have no residual postoperative pain. This study characterized the preoperative somatosensory profiles and provided possible interpretation of underlying pain mechanisms that might influence the development of postoperative pain. Forty hip OA patients with unilateral pain were assessed before and 6 weeks post-THA and compared with forty asymptomatic control subjects...
November 17, 2016: Pain
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