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https://www.readbyqxmd.com/read/28718671/freeze-dried-and-irradiated-allograft-bone-combined-with-fresh-autologous-coagula-promotes-angiogenesis-in-an-ectopic-bone-allograft-implantation-model
#1
Haibo Lu, Haoye Meng, Shibi Lu, Ling Qin, Bin Zhao, Aiyuan Wang, Jiang Peng, Wenjing Xu, Quanyi Guo, Jian Zhang
BACKGROUND: Freeze-dried and irradiated allograft bone (FIAB) is more easily impacted than fresh-frozen allograft bone (FAB) but has weaker incorporation efficiency. We combined FIAB with fresh autologous coagula to enhance donor-host incorporation after impaction during hip revision. METHODS: Thirty adult male Sprague-Dawley rats were sacrificed for bone allograft harvesting, and nine male rats were subjected to ectopic bone allograft implantation. For each rat, the container on the left (study) side was filled with freeze-dried allograft bone powder and fresh autologous blood coagula, whereas the right (control) side was filled with freeze-dried allograft bone powder and physiological saline...
July 18, 2017: Connective Tissue Research
https://www.readbyqxmd.com/read/28714764/abdominal-hollowing-reduces-lateral-trunk-displacement-during-single-leg-squats-in-healthy-females-but-does-not-affect-peak-hip-abduction-angle-or-knee-abductio-angle-moment
#2
Lukas D Linde, Jessica Archibald, Eve C Lampert, John Z Srbely
CONTEXT: Females suffer 4-6 times more non-contact anterior cruciate ligament (ACL) injuries than males due to neuromuscular control deficits of the hip musculature leading to increases in hip adduction angle, knee abduction angle, and knee abduction moment during dynamic tasks such as single-leg squats. Lateral trunk displacement has been further related to ACL injury risk in females, leading to the incorporation of core strength/stability exercises in ACL preventative training programs...
July 17, 2017: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/28712802/efficacy-of-a-pelvic-lateral-positioner-with-a-mechanical-cup-navigator-based-on-the-anatomical-pelvic-plane-in-total-hip-arthroplasty
#3
Kentaro Iwakiri, Akio Kobayashi, Yoichi Ohta, Yukihide Minoda, Kunio Takaoka, Hiroaki Nakamura
BACKGROUND: The acetabular component orientation in total hip arthroplasty (THA) is of critical importance to the good clinical results. However, traditional widely used cup alignment guides for cup placement are reported to be relatively unreliable. The present study aims at comparing a novel cup alignment guide, which can be attached to our anatomical pelvic plane (APP) pelvic lateral positioner for reducing discrepancies in sagittal pelvic tilt and indicate a targeted cup angle based on the APP, with a conventional cup alignment guide...
June 27, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28708989/sex-specific-hip-osteoarthritis-associated-gait-abnormalities-alterations-in-dynamic-hip-abductor-function-differ-in-men-and-women
#4
Kharma C Foucher
BACKGROUND: Hip osteoarthritis results in abnormal gait mechanics, but it is not known whether abnormalities are the same in men and women. The hypothesis tested was that gait abnormalities are different in men and women with hip osteoarthritis vs. sex-specific asymptomatic groups. METHODS: 150 subjects with mild through severe radiographic hip osteoarthritis and 159 asymptomatic subjects were identified from an Institutional Review Board-approved motion analysis data repository...
July 4, 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/28708200/periacetabular-bone-densitometry-after-total-hip-arthroplasty-with-highly-porous-titanium-cups-a-2-year-follow-up-prospective-study
#5
Leo Massari, Alessandro Bistolfi, Pier Paolo Grillo, Alda Borré, Gaetano Gigliofiorito, Carlotta Pari, Andrea Francescotto, Piermario Tosco, Davide Deledda, Laura Ravera, Araldo Causero
INTRODUCTION: Trabecular Titanium is an advanced cellular solid structure, composed of regular multiplanar hexagonal interconnected cells that mimic the morphology of the trabecular bone. This biomaterial demonstrated improved mechanical properties and enhanced osteoinduction and osteoconduction in several in vitro and in vivo studies. The aim of this study was to assess Trabecular Titanium osseointegration by measuring periacetabular changes in bone mineral density (BMD) with dual-emission X-ray absorptiometry (DEXA)...
July 1, 2017: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/28705543/oral-multimodal-analgesia-for-total-joint-arthroplasty
#6
Gregory J Golladay, Karl R Balch, David F Dalury, Jibanananda Satpathy, William A Jiranek
BACKGROUND: Oral multimodal analgesia for hip and knee arthroplasty is increasingly used as part of enhanced recovery protocols designed to minimize early postoperative pain and to facilitate early discharge, while minimizing undesirable side effects related to single-agent opioid administration. METHODS: This article is a review of previously published data evaluating the use of various oral medications in the management of postoperative pain after lower extremity arthroplasty and was presented as part of a symposium at the November 2016 AAHKS Annual Meeting...
May 11, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28704747/two-cases-of-late-medial-instability-of-the-knee-due-to-hip-disease-after-total-knee-arthroplasty
#7
Masanori Tsubosaka, Tomoyuki Matsumoto, Koji Takayama, Naoki Nakano, Ryosuke Kuroda
INTRODUCTION: There are few specific reports of late medial instability after total knee arthroplasty (TKA). We described two cases of late medial instability of the knee due to hip disease with osteoarthritis or rheumatoid arthritis after TKA, which required revision TKA. PRESENTATION OF CASES: An 82-year-old woman experienced right femoral neck fracture due to a fall that required conservative treatment at age 77 years and underwent left TKA at age 80 years. A 68-year-old woman underwent left TKA at age 54 years, right TKA at age 64 years, and left THA at age 67 years...
June 29, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28702381/importance-of-preclinical-evaluation-of-wear-in-hip-implant-designs-using-simulator-machines
#8
REVIEW
Rafael Mello Trommer, Márcia Marie Maru
Total hip arthroplasty (THA) is a surgical procedure that involves the replacement of the damaged joint of the hip by an artificial device. Despite the recognized clinical success of hip implants, wear of the articulating surfaces remains as one of the critical issues influencing performance. Common material combinations used in hip designs comprise metal-on-polymer (MoP), ceramic-on-polymer (CoP), metal-on-metal (MoM), and ceramic-on-ceramic (CoC). However, when the design of the hip implant is concerned besides the materials used, several parameters can influence its wear performance...
May 2017: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/28698540/epigallocatechin-gallate-attenuates-hip-fracture-induced-acute-lung-injury-by-limiting-mitochondrial-dna-mtdna-release
#9
Xiao-Dan Zhao, Hao Liu, Tao Li, Quan Gong, Wen-Li Zhang
BACKGROUND To study the protective effects and explore the mechanism of epigallocatechingallate (EGCG) on the hip fracture-induced acute lung injury. MATERIAL AND METHODS Thirty male Sprague-Dawley (SD) rats were randomly divided into the control group, hip fracture group, and hip fracture + EGCG (10 mg/Kg) group. After 24 h, blood samples, bronchoalveolar lavage fluid (BALF), and lung tissue were collected. Serum mitochondrial DNA (mtDNA) was measured by RT-PCR and BALF was used to perform cytological analysis and enzyme-linked immunosorbent assay (ELISA) assay...
July 12, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28695179/inflammatory-pseudotumor-after-ceramic-on-ceramic-total-hip-arthroplasty
#10
Joshua Campbell, Sean Rajaee, Earl Brien, Guy D Paiement
We present a unique case of a symptomatic adverse local tissue reaction in a patient with a ceramic-on-ceramic total hip bearing surface. To our knowledge, this pathological finding has not yet been described in a ceramic-on-ceramic articulation without a cobalt-chromium alloy trunnion or modular neck component as a source of metal wear. We conclude that despite its mechanical mostly benign wear characteristics, ceramic wear debris is not entirely inert and may lead to the development of adverse local tissue reaction...
June 2017: Arthroplasty Today
https://www.readbyqxmd.com/read/28693543/finite-element-analysis-of-porously-punched-prosthetic-short-stem-virtually-designed-for-simulative-uncemented-hip-arthroplasty
#11
Matthew Jian-Qiao Peng, Hai-Yan Chen, Yong Hu, XiangYang Ju, Bo Bai
BACKGROUND: There is no universal hip implant suitably fills all femoral types, whether prostheses of porous short-stem suitable for Hip Arthroplasty is to be measured scientifically. METHODS: Ten specimens of femurs scanned by CT were input onto Mimics to rebuild 3D models; their *stl format dataset were imported into Geomagic-Studio for simulative osteotomy; the generated *.igs dataset were interacted by UG to fit solid models; the prosthesis were obtained by the same way from patients, and bored by punching bears designed by Pro-E virtually; cements between femora and prosthesis were extracted by deleting prosthesis; in HyperMesh, all compartments were assembled onto four artificial joint style as: (a) cemented long-stem prosthesis; (b) porous long-stem prosthesis; (c) cemented short-stem prosthesis; (d) porous short-stem prosthesis...
July 11, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28692359/prevention-of-limb-length-discrepancy-in-total-hip-arthroplasty
#12
Babar Kayani, Jurek Pietrzak, Fahad S Hossain, Sujith Konan, Fares S Haddad
Total hip arthroplasty is a highly effective and cost-efficient procedure but postoperative limb length discrepancy is a common source of patient dissatisfaction and litigation. This article provides a systematic, stepwise approach for identifying and proactively managing risk factors associated with limb length discrepancy following total hip arthroplasty. This review explores preoperative history taking, clinical examination, radiological templating, implant positioning, soft tissue balancing, and intraoperative surgical techniques for minimizing leg length discrepancy while maintaining stability and restoring mechanical function following total hip arthroplasty...
July 2, 2017: British Journal of Hospital Medicine
https://www.readbyqxmd.com/read/28690745/closed-reduction-of-a-traumatic-hip-dislocation-in-children-case-report
#13
Achraf El Bakkaly, Fouad Ettayebi, Houda Oubeja, Mounir Erraji, Hicham Zerhouni
Traumatic dislocation of the hip in children is a rare disease. It only represents 5% of hip dislocations in all age groups. Before 10 years, the mechanism is often a minimal domestic accident; after 10 years, the dislocation occurs with the waning of an accident of the public highway. It is different from that of the adult by its rarity, its ease of reduction and better prognosis. This is an emergency trauma: risk necrosis of the femoral head (If delayed reduction). We report a rare case of a 3 year old boy, who suffered from bipolar trauma after a fall near his height of his house causing him a detachment of the right humerus and post-traumatic dislocation of the left hip...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28690039/retained-antibiotic-spacers-after-total-hip-and-knee-arthroplasty-resections-high-complication-rates
#14
Stephen M Petis, Kevin I Perry, Mark W Pagnano, Daniel J Berry, Arlen D Hanssen, Matthew P Abdel
BACKGROUND: Prolonged retention of an antibiotic spacer is occasionally chosen during treatment of periprosthetic joint infections after total hip arthroplasty (THA) and total knee arthroplasty (TKA). The purpose of our study was to evaluate the outcome of extended spacer retention. METHODS: We reviewed 1106 cases of periprosthetic joint infection after THA (n = 308) and TKA (n = 798) and identified 17 (5.5%) retained hip and 34 (4.3%) retained knee spacers. Most patients (35 of 51, 69%) underwent spacer retention because they were medically unfit for further surgery...
June 8, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28689681/locomotion-pattern-and-foot-pressure-adjustments-during-gentle-turns-in-healthy-subjects
#15
Kathrin E Peyer, Charlotte A Brassey, Kayleigh A Rose, William I Sellers
People suffering from locomotor impairment find turning manoeuvres more challenging than straight-ahead walking. Turning manoeuvres are estimated to comprise a substantial proportion of steps taken daily, yet research has predominantly focused on straight-line walking, meaning that the basic kinetic, kinematic and foot pressure adaptations required for turning are not as well understood. We investigated how healthy subjects adapt their locomotion patterns to accommodate walking along a gently curved trajectory (radius 2...
June 21, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28680452/vertical-leaping-mechanics-of-the-lesser-egyptian-jerboa-reveal-specialization-for-maneuverability-rather-than-elastic-energy-storage
#16
Talia Y Moore, Alberto M Rivera, Andrew A Biewener
BACKGROUND: Numerous historical descriptions of the Lesser Egyptian jerboa, Jaculus jaculus, a small bipedal mammal with elongate hindlimbs, make special note of their extraordinary leaping ability. We observed jerboa locomotion in a laboratory setting and performed inverse dynamics analysis to understand how this small rodent generates such impressive leaps. We combined kinematic data from video, kinetic data from a force platform, and morphometric data from dissections to calculate the relative contributions of each hindlimb muscle and tendon to the total movement...
2017: Frontiers in Zoology
https://www.readbyqxmd.com/read/28679961/islet-inflammation-and-ductal-proliferation-may-be-linked-to-increased-pancreatitis-risk-in-type-2-diabetes
#17
Belinda Schludi, Abu Saleh Md Moin, Chiara Montemurro, Tatyana Gurlo, Aleksey V Matveyenko, David Kirakossian, David W Dawson, Sarah M Dry, Peter C Butler, Alexandra E Butler
Pancreatitis is more frequent in type 2 diabetes mellitus (T2DM), although the underlying cause is unknown. We tested the hypothesis that ongoing β cell stress and apoptosis in T2DM induces ductal tree proliferation, particularly the pancreatic duct gland (PDG) compartment, and thus potentially obstructs exocrine outflow, a well-established cause of pancreatitis. PDG replication was increased 2-fold in human pancreas from individuals with T2DM, and was associated with increased pancreatic intraepithelial neoplasia (PanIN), lesions associated with pancreatic inflammation and with the potential to obstruct pancreatic outflow...
July 6, 2017: JCI Insight
https://www.readbyqxmd.com/read/28677227/the-atypical-dopamine-receptor-agonist-skf-83959-enhances-hippocampal-and-prefrontal-cortical-neuronal-network-activity-in-a-rat-model-of-cognitive-dysfunction
#18
Melissa L Perreault, Theresa Fan, Tomek J Banasikowski, Anthony A Grace, Susan R George
Deficits in neuronal network synchrony in hippocampus and prefrontal cortex have been widely demonstrated in disorders of cognitive dysfunction, including schizophrenia and Alzheimer's disease. The atypical dopamine agonist SKF 83959 has been shown to increase brain-derived neurotrophic factor signaling and suppress activity of glycogen synthase kinase-3 in PFC, two processes important to learning and memory. The purpose of this study was to therefore evaluate the impact of SKF 83959 on oscillatory deficits in methylazoxymethanol acetate (MAM) rat model of schizophrenia...
July 5, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/28673601/femoroacetabular-impingement-causes-osteoarthritis-of-the-hip-by-migration-and-micro-instability-of-the-femoral-head
#19
Henk Eijer, Tom Hogervorst
Femoroacetabular impingement is the condition whereby parts of the proximal femur mechanically collide with the acetabular rim leading to adjacent and contrecoup acetabular damage. Evidence is growing that at least for cam impingement, and perhaps less so for pincer impingement, there is a relation to the development of osteoarthritis. It has been demonstrated that surgery for impingement can improve function and decrease pain. Intuitively, it would then make sense that surgical intervention would prevent further degeneration...
July 2017: Medical Hypotheses
https://www.readbyqxmd.com/read/28666047/acute-intraprosthetic-dissociation-of-a-dual-mobility-hip-in-the-united-states
#20
Mitchell R Klement, Elizabeth W Hubbard, Samuel S Wellman, Paul F Lachiewicz
After decades of use in Europe, dual-mobility (DM) components for total hip arthroplasty (THA) were approved by the US Food and Drug Administration (FDA) in 2011 for use in the United States. DM-THAs are designed with an inner articulation between the femoral head and a larger polyethylene insert, and an outer articulation between the mobile polyethylene and a highly polished metal insert, to increase motion and minimize impingement. Intraprosthetic dissociation (IPD), defined as separation of the femoral head from the inner polyethylene articulation, is usually caused by polyethylene wear, and occurs 3 to 10 years after implantation...
May 2017: American Journal of Orthopedics
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