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https://www.readbyqxmd.com/read/28814336/risk-behaviour-determinants-among-people-who-inject-drugs-in-stockholm-sweden-over-a-10-year-period-from-2002-to-2012
#1
Niklas Karlsson, Michele Santacatterina, Kerstin Käll, Maria Hägerstrand, Susanne Wallin, Torsten Berglund, Anna Mia Ekström
BACKGROUND: People who inject drugs (PWID) frequently engage in injection risk behaviours exposing them to blood-borne infections. Understanding the underlying causes that drive various types and levels of risk behaviours is important to better target preventive interventions. METHODS: A total of 2150 PWID in Swedish remand prisons were interviewed between 2002 and 2012. Questions on socio-demographic and drug-related variables were asked in relation to the following outcomes: Having shared injection drug solution and having lent out or having received already used drug injection equipment within a 12 month recall period...
August 16, 2017: Harm Reduction Journal
https://www.readbyqxmd.com/read/28814121/perceptions-of-iranian-female-drug-users-toward-hiv-testing-a-qualitative-content-analysis
#2
Mansoureh Jamshidimanesh, Effat Merghati Khoie, Seyed Abbas Mousavi, Afsaneh Keramat, Mohammad Hassan Emamian
BACKGROUND: Drug-dependent women are the vulnerable population deprived of access to health services and also have particular relevance to public health perspective because they are important bridge population for driving HIV/AIDS epidemic. This qualitative study aimed to explore the perception of drug-dependent women regarding HIV testing. METHODS: In this qualitative study, we approached 23 women with substance use disorders in 2 of the selected drop-in centers in the south Tehran...
January 1, 2017: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/28800503/intravenous-heroin-use-in-haiphong-vietnam-need-for-comprehensive-care-including-methamphetamine-use-related-interventions
#3
Laurent Michel, Don C Des Jarlais, Huong Duong Thi, Oanh Khuat Thi Hai, Khuê Pham Minh, Marianne Peries, Roselyne Vallo, Thanh Nham Thi Tuyet, Giang Hoang Thi, Mai Le Sao, Jonathan Feelemyer, Vinh Vu Hai, Jean-Pierre Moles, Didier Laureillard, Nicolas Nagot
BACKGROUND: The aim of this study was to describe patterns among people who inject drugs (PWID), risk-related behaviours and access to methadone treatment, in order to design a large-scale intervention aiming to end the HIV epidemic in Haiphong, Vietnam. METHODS: A respondent-driven sampling (RDS) survey was first conducted to identify profiles of drug use and HIV risk-related behaviour among PWID. A sample of PWID was then included in a one-year cohort study to describe access to methadone treatment and associated factors...
August 2, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28797967/multipurpose-tenofovir-disoproxil-fumarate-electrospun-fibers-for-the-prevention-of-hiv-1-and-hsv-2-infections-in-vitro
#4
Kevin M Tyo, Hung R Vuong, Danial A Malik, Lee B Sims, Houda Alatassi, Jinghua Duan, Walter H Watson, Jill M Steinbach-Rankins
Sexually transmitted infections affect hundreds of millions of people worldwide. Both human immunodeficiency virus (HIV-1 and -2) and herpes simplex virus-2 (HSV-2) remain incurable, urging the development of new prevention strategies. While current prophylactic technologies are dependent on strict user adherence to achieve efficacy, there is a dearth of delivery vehicles that provide discreet and convenient administration, combined with prolonged-delivery of active agents. To address these needs, we created electrospun fibers (EFs) comprised of FDA-approved polymers, poly(lactic-co-glycolic acid) (PLGA) and poly(DL-lactide-co-ε-caprolactone) (PLCL), to provide sustained-release and in vitro protection against HIV-1 and HSV-2...
August 7, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28797018/editorial-atrocity-in-the-philippines-how-rodrigo-duterte-s-war-on-drug-users-may-exacerbate-the-burgeoning-hiv-epidemic
#5
Julia C Dombrowski, Jimmy Dorabjee, Steffanie A Strathdee
No abstract text is available yet for this article.
September 1, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28796591/utilization-of-buprenorphine-and-methadone-among-opioid-users-who-inject-drugs
#6
Judith I Tsui, Richard Burt, Hanne Thiede, Sara N Glick
BACKGROUND: There has been a rise in opioid abuse and related injection drug use in the United States and treatment for opioid use disorders may be underutilized. The study aim was to describe utilization of opioid agonist therapy (OAT), and assess factors associated with utilization of OAT, among persons who inject drugs (PWID) in the Seattle metropolitan area. METHODS: We used data from the 2015 National HIV Behavioral Surveillance (NHBS) system among PWID in the Seattle area...
August 10, 2017: Substance Abuse
https://www.readbyqxmd.com/read/28796293/il7ra-polymorphisms-are-not-associated-with-aids-progression
#7
Luz María Medrano, José Luis Jiménez, María A Jiménez-Sousa, Amanda Fernández-Rodíguez, Mónica Gutiérrez-Rivas, José María Bellón, José Ramón Blanco, Alexy Inciarte, Mª Ángeles Muñoz-Fernández, Salvador Resino
BACKGROUND: Our aim was to determine whether α-chain of the IL-7 Receptor (IL7RA) polymorphisms (rs10491434, rs6897932, and rs987106) are associated with the clinical pattern of AIDS progression in ART-naïve HIV-infected patients. METHODS: We carried out a cross-sectional study in 673 HIV-infected patients who were classified into three groups according to the clinical pattern of AIDS progression (188 long-term non-progressors (LTNPs), 334 moderate progressors (MPs), and 151 rapid progressors (RPs))...
August 10, 2017: European Journal of Clinical Investigation
https://www.readbyqxmd.com/read/28783374/hiv-and-cognitive-impairment-in-clinical-practice-the-evaluation-of-a-stepwise-screening-protocol-in-relation-to-clinical-outcomes-and-management
#8
Charlotte S Hakkers, Jordan M Kraaijenhof, Esther B van Oers-Hazelzet, Anne J M A Visser-Meily, Andy I M Hoepelman, Joop E Arends, Roos E Barth
Neurocognitive impairment (NCI) is an increasingly important comorbidity in an ageing HIV+ population. Despite the lack of available treatment modalities, screening for NCI is recommended. In the UMC Utrecht, yearly NCI screening is done using the Montreal Cognitive Assessment (MoCA) tool and the HIV Dementia Scale (HDS). The aim of this study was to evaluate this screening protocol in relation to clinical outcomes and management. A retrospective cohort study was performed in suppressed adult HIV+ patients...
August 7, 2017: AIDS Patient Care and STDs
https://www.readbyqxmd.com/read/28771449/using-technology-to-assess-and-intervene-with-illicit-drug-using-persons-at-risk-for-hiv
#9
Keith J Horvath, Sara Lammert, Sara LeGrand, Kathryn E Muessig, José A Bauermeister
PURPOSE OF REVIEW: This review describes recent literature on novel ways technology is used for assessment of illicit drug use and HIV risk behaviours, suggestions for optimizing intervention acceptability, and recently completed and ongoing technology-based interventions for drug-using persons at risk for HIV and others with high rates of drug use and HIV risk behaviour. RECENT FINDINGS: Among studies (n = 5) comparing technology-based to traditional assessment methods, those using Ecological Momentary Assessment (EMA) had high rates of reported drug use and high concordance with traditional assessment methods...
September 2017: Current Opinion in HIV and AIDS
https://www.readbyqxmd.com/read/28771077/the-changing-face-of-women-living-with-hiv-in-western-ukraine
#10
Divya Dethier, Natasha Rybak, Priya Hirway, Mariya Bachmaha, Jennifer Carroll, Andriy Sorokolit, Timothy Flanigan, Maryana Sluzhynska
Ukraine has the second largest HIV epidemic in Eastern Europe/Central Asia. This study characterizes the demographics of HIV-infected women in the Lviv region of western Ukraine, patterns in their clinical presentation, and factors associated with delays in seeking care. A retrospective chart review was conducted of 622 HIV-infected women who registered for HIV treatment at the Lviv AIDS Center between 2008 and 2013. A total of 81.6% of women were infected through heterosexual transmission and the remaining 18...
January 1, 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28762652/hiv-incidence-in-the-estonian-population-in-2013-determined-using-the-hiv-1-limiting-antigen-avidity-assay
#11
P Soodla, R Simmons, K Huik, M Pauskar, E-L Jõgeda, H Rajasaar, E Kallaste, M Maimets, R Avi, G Murphy, K Porter, I Lutsar
OBJECTIVES: Estonia has one the highest number of new HIV diagnoses in the European Union, mainly among injecting drug users and heterosexuals. Little is known of HIV incidence, which is crucial for limiting the epidemic. Using a recent HIV infection testing algorithm (RITA) assay, we aimed to estimate HIV incidence in 2013. METHODS: All individuals aged ≥18 years newly-diagnosed with HIV in Estonia January- December 2013, except blood donors and those undergoing antenatal screening, were included...
August 1, 2017: HIV Medicine
https://www.readbyqxmd.com/read/28759568/cannabinoid-receptor-2-63-rr-variant-is-independently-associated-with-severe-necroinflammation-in-hiv-hcv-coinfected-patients
#12
Caterina Sagnelli, Caterina Uberti-Foppa, Hamid Hasson, Giulia Bellini, Carmine Minichini, Stefania Salpietro, Emanuela Messina, Diletta Barbanotti, Marco Merli, Francesca Punzo, Nicola Coppola, Adriano Lazzarin, Evangelista Sagnelli, Francesca Rossi
OBJECTIVE: This is the first study to analyze the impact of the rs35761398 variant of the CNR2 gene leading to the substitution of GLN (Q) of codon 63 of the cannabinoid receptor 2 (CB2) with ARG (R) on the clinical presentation of chronic hepatitis in HIV/HCV coinfected patients. METHODS: Enrolled in this study were 166 consecutive HIV/HCV coinfected patients, naïve for HCV treatment. A pathologist unaware of the patients' condition graded liver fibrosis, necroinflammation (Ishak) and steatosis...
2017: PloS One
https://www.readbyqxmd.com/read/28753637/collaborative-update-of-a-rule-based-expert-system-for-hiv-1-genotypic-resistance-test-interpretation
#13
Roger Paredes, Philip L Tzou, Gert van Zyl, Geoff Barrow, Ricardo Camacho, Sergio Carmona, Philip M Grant, Ravindra K Gupta, Raph L Hamers, P Richard Harrigan, Michael R Jordan, Rami Kantor, David A Katzenstein, Daniel R Kuritzkes, Frank Maldarelli, Dan Otelea, Carole L Wallis, Jonathan M Schapiro, Robert W Shafer
INTRODUCTION: HIV-1 genotypic resistance test (GRT) interpretation systems (IS) require updates as new studies on HIV-1 drug resistance are published and as treatment guidelines evolve. METHODS: An expert panel was created to provide recommendations for the update of the Stanford HIV Drug Resistance Database (HIVDB) GRT-IS. The panel was polled on the ARVs to be included in a GRT report, and the drug-resistance interpretations associated with 160 drug-resistance mutation (DRM) pattern-ARV combinations...
2017: PloS One
https://www.readbyqxmd.com/read/28751487/ability-to-join-the-workforce-and-work-productivity-among-drug-users-under-methadone-maintenance-treatment-in-a-mountainous-area-of-northern-vietnam-a-cross-sectional-study
#14
Vuong Minh Nong, Victoria L Boggiano, Lan Huong Thi Nguyen, Cuong Tat Nguyen, Long Hoang Nguyen, Tran Xuan Bach, Hung Van Nguyen, Canh Dinh Hoang, Carl A Latkin, Minh Thuc Thi Vu
OBJECTIVES: A major measure of treatment success for drug users undergoing rehabilitation is the ability to enter the workforce and generate income. This study examines the absenteeism and productivity among people who inject drugs (PWID) enrolled in methadone maintenance treatment (MMT) in Northern Vietnam. SETTING: We conducted a cross-sectional study in two clinics in Tuyen Quang province. PARTICIPANTS: A total of 241 patients enrolled in MMT...
July 26, 2017: BMJ Open
https://www.readbyqxmd.com/read/28738467/-epidemiological-survey-of-prevalence-of-hiv-infection-syphilis-and-hepatitis-c-in-female-sex-workers-and-other-6-risk-populations-in-tibet-autonomous-region
#15
S Lu, Y Cui, W Guo, D M Li, J Sun
Objective: To understand the prevalence of HIV infection, syphilis and hepatitis C and related behavioral factors in female sex workers (FSWs) and other 6 risk populations in Tibet Autonomous Region. Methods: A cross-sectional survey was conducted among 2 000 FSWs, 200 men who have sex with men (MSM), 200 drug users, 1 200 male migrants, 5 600 young students, as well as hospital patients and pregnant women in Lhasa, Qamdo, Nyingchi, Xigaze Shannan, Ali and Nagqum from June to December 2015. Face to face interviews were conducted to collect their demographic and behavioral information, and blood samples were collected for the tests of HIV, syphilis and hepatitis C virus (HCV) antibodies...
July 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28732503/opium-trade-and-the-spread-of-hiv-in-the-golden-crescent
#16
REVIEW
Syeda Ayesha Farooq, Mohammad Hafiz Rasooly, Syed Hani Abidi, Kayvon Modjarrad, Syed Ali
The Golden Crescent region of South Asia-comprising Afghanistan, Iran, and Pakistan-is a principal global site for opium production and distribution. Over the past few decades, war, terrorism, and a shifting political landscape have facilitated an active heroin trade throughout the region. Protracted conflict has exacerbated already dire socio-economic conditions and political strife within the region and contributed to a consequent rise in opiate trafficking and addiction among the region's inhabitants. The worsening epidemic of injection drug use has paralleled the rising incidence of HIV and other blood-borne infections in the region and drawn attention to the broader implications of the growing opiate trade in the Golden Crescent...
July 21, 2017: Harm Reduction Journal
https://www.readbyqxmd.com/read/28725561/bronchopleural-and-pleurocutaneous-fistula-in-hiv-patient-with-pulmonary-tuberculosis
#17
Filipa Duarte-Ribeiro, Cátia Dias, Margarida Mota
We present a 37-year-old man intravenous drug user, with HIV/HCV/HBV co-infection, lymph node tuberculosis 10 years before (completed 12 months of treatment), and left lobar pneumonia 4 years earlier complicated by empyema (treated with left lower lobectomy with a persistent bronchopleural fistula) who was admitted to the emergency department with caseous-purulent drainage and exteriorization of air from an orifice in the chest wall. Acid-fast bacilli were identified in this drainage. A pleurocutaneous fistula was evident on the chest computed tomography scan...
2017: IDCases
https://www.readbyqxmd.com/read/28719295/regional-differences-in-the-prevalence-of-major-opportunistic-infections-among-antiretroviral-na%C3%A3-ve-human-immunodeficiency-virus-patients-in-japan-northern-thailand-northern-vietnam-and-the-philippines
#18
Louie Mar A Gangcuangco, Ikumi Sawada, Naho Tsuchiya, Cuong D Do, Thanh Thuy T Pham, Archawin Rojanawiwat, Marissa Alejandria, Katerina Leyritana, Yoshiyuki Yokomaku, Panita Pathipvanich, Koya Ariyoshi
To identify regional differences in the distribution of opportunistic infections (OIs) among human immunodeficiency virus (HIV)-infected patients in Asia, the medical records of antiretroviral therapy (ART)-naïve patients who attended the following tertiary hospitals from 2003 to 2011 were reviewed: Nagoya Medical Center (NMC, Nagoya, Japan), Lampang Hospital (LPH, Lampang, northern Thailand), Bach Mai Hospital (BMH, Hanoi, northern Vietnam), and Philippine General Hospital (PGH, Manila, Philippines). Logistic regression analyses were performed to identify associations between country of origin and risk of major OIs...
July 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28716791/factors-associated-with-nicotine-dependence-during-methadone-maintenance-treatment-findings-from-a-multisite-survey-in-vietnam
#19
Huyen Phuc Do, Long Hoang Nguyen, Nhung Phuong Thi Nguyen, Chau Ngo, Huong Lan Thi Nguyen, Giang Tong Le, Linh Khanh Nguyen, Cuong Tat Nguyen, Bach Xuan Tran, Huong Thi Le, Thuc Minh Thi Vu, Huong Thu Thi Phan, Tho Dinh Tran, Carl A Latkin, Michael P Dunne
OBJECTIVES: Smoking is associated with adverse health outcomes among drug users, including those in treatment. To date, however, there has been little evidence about smoking patterns among people receiving opioid-dependence treatment in developing countries. We examined self-reported nicotine dependence and associated factors in a large sample of opioid-dependent patients receiving methadone maintenance treatment (MMT) in northern Vietnam. SETTING: Five clinics in Hanoi (urban area) and Nam Dinh (rural area)...
July 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/28716395/-it-ruined-my-life-the-effects-of-the-war-on-drugs-on-people-who-inject-drugs-pwid-in-rural-puerto-rico
#20
R Abadie, C Gelpi-Acosta, C Davila, A Rivera, M Welch-Lazoritz, K Dombrowski
BACKGROUND: The War on Drugs has raised the incarceration rates of racial minorities for non-violent drug-related crimes, profoundly stigmatized drug users, and redirected resources from drug prevention and treatment to militarizing federal and local law enforcement. Yet, while some states consider shifting their punitive approach to drug use, to one based on drug treatment and rehabilitation, nothing suggests that these policy shifts are being replicated in Puerto Rico. METHODS: This paper utilizes data from 360 PWID residing in four rural towns in the mountainous area of central Puerto Rico...
July 14, 2017: International Journal on Drug Policy
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