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https://www.readbyqxmd.com/read/28086880/influence-of-border-disease-virus-bdv-on-serological-surveillance-within-the-bovine-virus-diarrhea-bvd-eradication-program-in-switzerland
#1
V Kaiser, L Nebel, G Schüpbach-Regula, R G Zanoni, M Schweizer
BACKGROUND: In 2008, a program to eradicate bovine virus diarrhea (BVD) in cattle in Switzerland was initiated. After targeted elimination of persistently infected animals that represent the main virus reservoir, the absence of BVD is surveilled serologically since 2012. In view of steadily decreasing pestivirus seroprevalence in the cattle population, the susceptibility for (re-) infection by border disease (BD) virus mainly from small ruminants increases. Due to serological cross-reactivity of pestiviruses, serological surveillance of BVD by ELISA does not distinguish between BVD and BD virus as source of infection...
January 13, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/27997620/molecular-and-serological-survey-of-selected-viruses-in-free-ranging-wild-ruminants-in-iran
#2
Farhid Hemmatzadeh, Wayne Boardman, Arezo Alinejad, Azar Hematzade, Majid Kharazian Moghadam
A molecular and serological survey of selected viruses in free-ranging wild ruminants was conducted in 13 different districts in Iran. Samples were collected from 64 small wild ruminants belonging to four different species including 25 Mouflon (Ovis orientalis), 22 wild goat (Capra aegagrus), nine Indian gazelle (Gazella bennettii) and eight Goitered gazelle (Gazella subgutturosa) during the national survey for wildlife diseases in Iran. Serum samples were evaluated using serologic antibody tests for Peste de petits ruminants virus (PPRV), Pestiviruses [Border Disease virus (BVD) and Bovine Viral Diarrhoea virus (BVDV)], Bluetongue virus (BTV), Bovine herpesvirus type 1 (BHV-1), and Parainfluenza type 3 (PI3)...
2016: PloS One
https://www.readbyqxmd.com/read/27980135/financial-boost-for-bvd-eradication-in-northern-ireland
#3
(no author information available yet)
No abstract text is available yet for this article.
December 17, 2016: Veterinary Record
https://www.readbyqxmd.com/read/27978850/ct-perfusion-measurements-in-pancreatic-carcinoma-with-different-kinetic-models-is-there-a-chance-for-tumour-grading-based-on-functional-parameters
#4
Sven Schneeweiß, Marius Horger, Anja Grözinger, Konstantin Nikolaou, Dominik Ketelsen, Roland Syha, Gerd Grözinger
BACKGROUND: To evaluate the interchangeability of perfusion parameters obtained with help of models used for post-processing of perfusion-CT images in pancreatic adenocarcinoma and to determine the mean values and ranges of perfusion in different tumour gradings. METHODS: Perfusion-CT imaging was performed prospectively in 48 consecutive patients with pancreatic adenocarcinoma. In 42 patients biopsy-proven tumor grading was available (4 × G1/24 × G2/14 × G3/6× unknown)...
December 15, 2016: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/27913251/unmapped-reads-from-cattle-rnaseq-data-a-source-for-missing-and-misassembled-sequences-in-the-reference-assemblies-and-for-detection-of-pathogens-in-the-host
#5
Tahir Usman, Frieder Hadlich, Wiebke Demasius, Rosemarie Weikard, Christa Kühn
Usually, reads from transcriptome sequencing data unmapped to the target species' reference genome are disregarded. A recent RNAseq project on the new fatal disease Bovine Neonatal Pancytopenia had indicated an unexplained immune response signature to a double-stranded RNA virus. To unravel its background, contigs were de novo assembled from unmapped RNAseq reads and aligned against the bovine genome assemblies and multispecies NCBI databases. Lack of genuine virus sequence contigs rejected the hypothesis of a live virus being causal for the unexplained immune response...
January 2017: Genomics
https://www.readbyqxmd.com/read/27865262/soluble-forms-of-cd46-are-detected-in-bos-taurus-plasma-and-neutralize-bvdv-the-bovine-pestivirus
#6
Nidal Alzamel, Calixte Bayrou, Annabelle Decreux, Daniel Desmecht
The pestivirus bovine viral diarrhea virus (BVDV) is known to bind to the CD46 molecule, which subsequently promotes entry of the virus. Mapping of the BVD-virion-binding site has shown that two peptides, 66EQIV69 and 82GQVLAL87, located on antiparallel beta sheets in the most distal complement control protein module (CCP1), provide the attachment platform. In the present study, we reveal new CD46-encoding transcripts that are predicted to encode CCP1-containing soluble forms. Further, we show that the serum of most adult cattle contains soluble CD46 (sCD46) and that a recombinant soluble isoform neutralizes BVDV infectivity in an in vitro assay...
December 2016: Comparative Immunology, Microbiology and Infectious Diseases
https://www.readbyqxmd.com/read/27863293/the-conical-stent-in-coronary-artery-improves-hemodynamics-compared-with-the-traditional-cylindrical-stent
#7
Yi Yu, Yujie Zhou, Qian Ma, Shuo Jia, Sijing Wu, Yan Sun, Xiaoli Liu, Yingxin Zhao, Yuyang Liu, Dongmei Shi
OBJECTIVES: This study sought to explore the efficacy of the conical stent implantation in the coronary artery by comparing the effects of cylindrical and conical stents on wall shear stress (WSS) and velocity of flow and fractional flow reserve (FFR). BACKGROUND: The traditional cylindrical stent currently used in the percutaneous coronary intervention (PCI) has a consistent diameter, which does not match the physiological change of the coronary artery. On the contrary, as a new patent, the conical stent with tapering lumen is consistent with the physiological change of vascular diameter...
January 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/27843266/heat-shock-protein-concentration-and-clarity-of-porcine-lenses-incubated-at-elevated-temperatures
#8
T M Dzialoszynski, K J Milne, J R Trevithick, E G Noble
PURPOSE: To quantify the concentration of heat shock proteins in lenses in lens organ culture at elevated temperatures, and to examine the relation between elevated temperature and lens clarity. METHODS: Pig lenses obtained from a local abattoir were dissected aseptically and incubated in medium M199 without serum for 4 days to stabilize, and lenses with protein leakage of less than 10 mg/l were obtained for heat shock exposure. Heat shock was performed by incubation for 1 h in M199 without serum at various temperatures ranging from 37 °C to 55 °C...
2016: Molecular Vision
https://www.readbyqxmd.com/read/27836034/temporal-trends-in-the-retention-of-bvd-calves-and-associated-animal-and-herd-level-risk-factors-during-the-compulsory-eradication-programme-in-ireland
#9
T A Clegg, D A Graham, P O'Sullivan, G McGrath, S J More
The national BVD eradication programme in Ireland started on a voluntary basis in 2012, becoming compulsory in 2013. The programme relies on accurate identification and prompt removal of BVD+ calves. However, a minority of herd owners have chosen to retain BVD+ animals (defined as still being alive more than seven weeks after the date of the initial test), typically with a view to fattening them to obtain some salvage value. During each year of the programme, additional measures have been introduced and implemented to encourage prompt removal of BVD+ animals...
November 1, 2016: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/27805246/bovine-neonatal-pancytopenia-correlation-between-clinical-symptoms-hematological-parameters-and-lifespan
#10
Marek Gehrke, Vivian Junge, Jędrzej M Jaśkowski, Mirosław P Polak, Krzysztof Urbaniak, Aleksandra Żuraw
OBJECTIVE: To compare the hematological parameters and clinical symptoms between Bovine Neonatal Pancytopenia (BNP) diseased calves dying before and after 14 days of life. MATERIAL AND METHODS: Clinical observations included 47 calves from dams which underwent a 3-year vaccination program with the inactivated PregSure(®) BVD vaccine. In 25 of these 47 BNP affected calves blood examinations were performed and in 22 dead calves diagnosis was mainly based on post-mortem findings...
December 5, 2016: Tierärztliche Praxis. Ausgabe G, Grosstiere/Nutztiere
https://www.readbyqxmd.com/read/27764130/first-results-in-the-use-of-bovine-ear-notch-tag-for-bovine-viral-diarrhoea-virus-detection-and-genetic-analysis
#11
Christian Quinet, Guy Czaplicki, Elise Dion, Fabiana Dal Pozzo, Anke Kurz, Claude Saegerman
BACKGROUND: Infection due to bovine viral diarrhoea virus (BVDV) is endemic in most cattle-producing countries throughout the world. The key elements of a BVDV control programme are biosecurity, elimination of persistently infected animals and surveillance. Bovine viral diarrhoea (BVD) is a notifiable disease in Belgium and an official eradication programme started from January 2015, based on testing ear notches sampled during the official identification and registration of calves at birth...
2016: PloS One
https://www.readbyqxmd.com/read/27717350/incidence-of-bovine-neonatal-pancytopenia-in-243-farms-in-germany
#12
Frederike Reichmann, Annette Pfitzner, Guenter Rademacher, Elke Schwedinger, Klaus Cussler, Carola M Sauter-Louis
BACKGROUND: Several research groups from different European countries have worked on the aetiopathogenesis of bovine neonatal pancytopenia (BNP) and an association between the use of the vaccine PregSure BVD (Pfizer, Germany) and the development of this haemorrhagic disease was confirmed. Because BNP is not a notifiable disease, it is difficult to obtain information on its incidence. Based on pharmacovigilance (PhV) data, which are the only officially available data at the national level, the incidence of BNP is considered low...
October 7, 2016: BMC Veterinary Research
https://www.readbyqxmd.com/read/27687927/existence-of-bovine-neonatal-pancytopenia-before-the-year-2005-retrospective-evaluation-of-215-cases-of-haemorrhagic-diathesis-in-cattle
#13
A Stoll, A Pfitzner-Friedrich, F Reichmann, J Rauschendorfer, A Roessler, G Rademacher, G Knubben-Schweizer, C Sauter-Louis
Haemorrhagic diathesis (HD) in cattle is a relatively rare syndrome that can have many different causes. With the occurrence of bovine neonatal pancytopenia (BNP) in 2007, the number of cases of HD in cattle has increased. This led to an enhanced interest in diseases presenting with bleeding disorders. The possible causes of HD in cattle, the clinical findings, and the course of various diseases are described and evaluated. Furthermore, we determined whether cases of BNP occurred before the introduction of the vaccine Pregsure BVD since its widespread use was associated with the syndrome...
October 2016: Veterinary Journal
https://www.readbyqxmd.com/read/27617959/forsythoside-a-inhibits-bvdv-replication-via-traf2-dependent-cd28-4-1bb-signaling-in-bovine-pbmcs
#14
Quan-Jiang Song, Xiao-Gang Weng, Dong-Jie Cai, Wang Zhang, Jiu-Feng Wang
Bovine viral diarrhea virus (BVDV), the causative agent of bovine viral diarrhea/mucosal disease (BVD/MD), is an important pathogen of cattle and other wild animals throughout the world. BVDV infection typically leads to an impaired immune response in cattle. In the present study, we investigated the effect of Forsythoside A (FTA) on BVDV infection of bovine peripheral blood mononuclear cells (PBMCs). We found that Forsythoside A could not only promote proliferation of PBMCs and T cells activation but also inhibit the replication of BVDV as well as apoptosis induced by BVDV...
2016: PloS One
https://www.readbyqxmd.com/read/27513006/identification-of-a-cyanine-dye-labeled-peptidic-ligand-for-y1r-and-y4r-based-upon-the-neuropeptide-y-c-terminal-analogue-bvd-15
#15
Mengjie Liu, Rachel R Richardson, Simon J Mountford, Lei Zhang, Matheus H Tempone, Herbert Herzog, Nicholas D Holliday, Philip E Thompson
Traceable truncated Neuropeptide Y (NPY) analogues with Y1 receptor (Y1R) affinity and selectivity are highly desirable tools in studying receptor location, regulation, and biological functions. A range of fluorescently labeled analogues of a reported Y1R/Y4R preferring ligand BVD-15 have been prepared and evaluated using high content imaging techniques. One peptide, [Lys(2)(sCy5), Arg(4)]BVD-15, was characterized as an Y1R antagonist with a pKD of 7.2 measured by saturation analysis using fluorescent imaging...
September 21, 2016: Bioconjugate Chemistry
https://www.readbyqxmd.com/read/27486768/functional-intratumoral-lymphatics-in-patient-derived-xenograft-models-of-squamous-cell-carcinoma-of-the-uterine-cervix-implications-for-lymph-node-metastasis
#16
Einar K Rofstad, Ruixia Huang, Kanthi Galappathi, Lise Mari K Andersen, Catherine S Wegner, Anette Hauge, Jon-Vidar Gaustad, Trude G Simonsen
Studies of cell line-derived human tumor xenografts have suggested that the lymphatics seen in immunohistochemical preparations from non-peripheral regions of tumors are nonfunctional. In this investigation, lymphangiogenesis, hemangiogenesis, and lymph node metastasis were studied in patient-derived xenograft (PDX) models of carcinoma of the uterine cervix. Lymph vessel density (LVD) and blood vessel density (BVD) were measured in immunohistochemical preparations. The expression of angiogenesis-related genes was investigated by quantitative PCR...
August 30, 2016: Oncotarget
https://www.readbyqxmd.com/read/27441213/bvd-2-outbreak-leads-to-high-losses-in-cattle-farms-in-western-germany
#17
Jörn Gethmann, Timo Homeier, Mark Holsteg, Horst Schirrmeier, Michael Saßerath, Bernd Hoffmann, Martin Beer, Franz J Conraths
In November 2012, a dairy farmer in the district Kleve first observed a reduction in milk yield, respiratory symptoms, nasal discharge, fever, sporadic diarrhoea and sudden deaths in dairy cows and calves. In the following months, further farms were found infected with cattle showing similar clinical signs. An epidemiological investigation was carried out to identify the source of infection, the date of introduction, potential transmission pathways and to analyse the extent of the epidemic. Furthermore, laboratory analyses were conducted to characterise the causative agent...
September 2015: Heliyon
https://www.readbyqxmd.com/read/27375947/detection-of-retinal-blood-vessel-changes-in-multiple-sclerosis-with-optical-coherence-tomography
#18
Basanta Bhaduri, Ryan M Nolan, Ryan L Shelton, Lara A Pilutti, Robert W Motl, Heather E Moss, John H Pula, Stephen A Boppart
Although retinal vasculitis is common in multiple sclerosis (MS), it is not known if MS is associated with quantitative abnormalities in retinal blood vessels (BVs). Optical coherence tomography (OCT) is suitable for examining the integrity of the anterior visual pathways in MS. In this paper we have compared the size and number of retinal blood vessels in patients with MS, with and without a history of optic neuritis (ON), and control subjects from the cross-sectional retinal images from OCT. Blood vessel diameter (BVD), blood vessel number (BVN), and retinal nerve fiber layer thickness (RNFLT) were extracted from OCT images collected from around the optic nerves of 129 eyes (24 control, 24 MS + ON, 81 MS-ON) of 71 subjects...
June 1, 2016: Biomedical Optics Express
https://www.readbyqxmd.com/read/27365236/bva-joins-bvd-coalition
#19
(no author information available yet)
No abstract text is available yet for this article.
July 2, 2016: Veterinary Record
https://www.readbyqxmd.com/read/27342097/prevalence-of-bovine-viral-diarrhoea-virus-in-cattle-farms-in-hungary
#20
Ágnes Szabára, Zsolt Lang, József Földi, Ákos Hornyák, Tamás Abonyi, László Ózsvári
A study was performed to survey the virological prevalence of bovine viral diarrhoea (BVD) virus (BVDV) in cattle herds in Hungary between 2008 and 2012. A total of 40,413 samples for BVDV detection and 24,547 samples for antibody testing were collected from 3,247 herds (570,524 animals), thus representing approximately 75% of the cattle population in Hungary. Retrospective Bayesian analysis demonstrated that (1) the herd-level true virus prevalence was 12.4%, (2) the mean individual (within-herd) true virus prevalence was 7...
June 2016: Acta Veterinaria Hungarica
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