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bioresorbable vascular scaffold

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https://www.readbyqxmd.com/read/28741575/the-drug-eluting-absorbable-magnesium-vascular-scaffold-in-complex-coronary-bifurcations-insights-from-an-in-vivo-multimodality-imaging-study
#1
Johan Bennett, Maarten Vanhaverbeke, Nina Vanden Driessche, Nick Hiltrop, Tom Adriaenssens, Walter Desmet, Peter Sinnaeve, Christophe Dubois
AIMS: This acute in-vivo study sought to provide insights regarding the feasibility of performing complex bifurcation stenting with Magmaris magnesium-alloy bioresorbable scaffolds (Biotronik,Bulach, Switzerland). METHODS AND RESULTS: Twenty-five New-Zealand-White rabbits underwent stenting of non-diseased aorto-iliac bifurcations with Magmaris using provisional (PS,n=5), culotte (n=6), modified-T (n=6), or T-and-protrusion (TAP,n=8) stenting techniques. Angiography, optical coherence tomography and micro-computed tomography were performed...
July 25, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28734925/coronary-ct-angiography-and-bioresorbable-vascular-scaffolds-is-there-clarity
#2
EDITORIAL
Joaquin E Cigarroa
No abstract text is available yet for this article.
July 13, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28734923/diagnostic-accuracy-of-coronary-ct-angiography-for%C3%A2-the-evaluation-of-bioresorbable-vascular-scaffolds
#3
Carlos Collet, Bernard Chevalier, Angel Cequier, Jean Fajadet, Marcello Dominici, Steffen Helqvist, A J Van Boven, Dariusz Dudek, Dougal McClean, Manuel Almeida, Jan J Piek, Erhan Tenekecioglu, Antonio Bartorelli, Stephan Windecker, Patrick W Serruys, Yoshinobu Onuma
OBJECTIVES: To assess the diagnostic accuracy of coronary computed tomography angiography (CTA) for bioresorbable vascular scaffold (BVS) evaluation. BACKGROUND: Coronary CTA has emerged as a noninvasive method to evaluate patients with suspected or established coronary artery disease. The diagnostic accuracy of coronary CTA to evaluate angiographic outcomes after BVS implantation has not been well established. METHODS: In the ABSORB II (A Bioresorbable Everolimus-Eluting Scaffold Versus a Metallic Everolimus-Eluting Stent II) study, patients were randomized either to receive treatment with the BVS or everolimus-eluting metallic stent...
July 13, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28732815/2-year-outcomes-with-the-absorb-bioresorbable-scaffold-for-treatment-of-coronary-artery-disease-a-systematic-review-and-meta-analysis-of-seven-randomised-trials-with-an-individual-patient-data-substudy
#4
Ziad A Ali, Patrick W Serruys, Takeshi Kimura, Runlin Gao, Stephen G Ellis, Dean J Kereiakes, Yoshinobu Onuma, Charles Simonton, Zhen Zhang, Gregg W Stone
BACKGROUND: Bioresorbable vascular scaffolds (BVS) offer the potential to improve long-term outcomes of percutaneous coronary intervention after their complete bioresorption. Randomised trials have shown non-inferiority between BVS and metallic drug-eluting stents at 1 year in composite safety and effectiveness outcomes, although some increases in rates of target vessel-related myocardial infarction and device thrombosis were identified. Outcomes of BVS following the first year after implantation are unknown...
July 18, 2017: Lancet
https://www.readbyqxmd.com/read/28725934/-scaffold-based-bone-tissue-engineering
#5
REVIEW
B M Holzapfel, M Rudert, D W Hutmacher
Tissue engineering provides the possibility of regenerating damaged or lost osseous structures without the need for permanent implants. Within this context, biodegradable and bioresorbable scaffolds can provide structural and biomechanical stability until the body's own tissue can take over their function. Additive biomanufacturing makes it possible to design the scaffold's architectural characteristics to specifically guide tissue formation and regeneration. Its nano-, micro-, and macro-architectural properties can be tailored to ensure vascularization, oxygenation, nutrient supply, waste exchange, and eventually ossification not only in its periphery but also in its center, which is not in direct contact with osteogenic elements of the surrounding healthy tissue...
July 19, 2017: Der Orthopäde
https://www.readbyqxmd.com/read/28714525/dedicated-bifurcation-stents-or-regular-drug-eluting-stents-in-distal-left-main-stenosis-a-retrospective-study
#6
Adam Kern, Robert J Gil, Krystian Bojko, Bartłomiej Rzeszowski, Krzysztof Bednarski, Jerzy Górny, Jacek Bil
BACKGROUND: Mainly atherosclerosis develops in distal left main (LM) within bifurcation or trifurcation. The aim of this study was to analyze the strategy of distal LM stenosis treatment and associated clinical outcomes in a large hospital in Northern Poland. METHODS: The study population consisted of consecutive patients with stable coronary artery disease or acute coronary syndrome (ACS) and distal LM stenosis who were hospitalized between June 2012 and June 2013...
July 17, 2017: Cardiology Journal
https://www.readbyqxmd.com/read/28707440/everolimus-eluting-bioresorbable-vascular-scaffolds-can-we-absorb-the-risk-in-complex-pci
#7
EDITORIAL
Firas Zahr, Joaquin E Cigarroa
BVS, as compared with DES, have higher stent thrombosis (ST) rates. BVS may prove reasonable in patients with complex anatomy. Future trials will be necessary to guide clinicians regarding whether BVS are equivalent to DES in patients with noncomplex or complex coronary anatomy.
July 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28707316/ticagrelor-and-absorb-bioresorbable-vascular-scaffold-implantation-for-recovery-of-vascular-function-after-successful-chronic-total-occlusion-recanalization-tiger-bvs-trial-rationale-and-study-design
#8
Salvatore Brugaletta, Josep Gomez-Lara, Juan Caballero, Luis Ortega-Paz, Luis Teruel, Miriam Jimenez Fernandez, Rafael Romaguera, Vicente Alcalde Martinez, Marcos Ñato, Eduardo Molina Navarro, Joan-Antoni Gomez-Hospital, Concepcion Correa Vilches, Maria Joyera, Angel Cequier, Manel Sabate
OBJECTIVES: To explore the role of ticagrelor versus clopidogrel in coronary blood flow normalization immediately after chronic coronary total occlusion (CTO) recanalization. BACKGROUND: Coronary vascular function of a CTO immediately after recanalization is demonstrated to be poor. METHODS: The TIGER BVS is a prospective, double-randomized, open-label, two parallel-group controlled clinical trial to evaluate efficacy of ticagrelor versus clopidogrel in improving vascular function of coronary segment distal to CTO immediately after CTO recanalization...
July 14, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28705057/applicability-and-procedural-success-rate-of-bioresorbable-vascular-scaffolds-for-percutaneous-coronary-intervention-in-an-all-comer-cohort-of-383-consecutive-patients
#9
Christian Schlundt, Stephan Achenbach, Fabiola Felten, Jens Roether, Mohamed Marwan, Holger Nef, Josef Ludwig, Monique Tröbs
Objectives The purpose of this study was to determine applicability and procedural success of bioresorbable vascular scaffolds (BVS) for percutaneous coronary intervention (PCI) in an all-comer cohort. Background BVS use in bifurcations and severely calcified lesions is not recommended, and a relatively large crossing profile may cause limitations. It is has never been studied how widely BVS can be applied in all-comer cohorts. Methods In 383 consecutive patients (acute coronary syndrome: 124, stable coronary disease 259), a BVS (Absorb) was used as first-line device unless any of the following contraindications were present: bifurcation with side branch >2...
July 14, 2017: Acta Cardiologica
https://www.readbyqxmd.com/read/28701488/comparative-biomechanical-behavior-and-healing-profile-of-a-novel-thinned-wall-ultrahigh-molecular-weight-amorphous-poly-l-lactic-acid-sirolimus-eluting-bioresorbable-coronary-scaffold
#10
Yanping Cheng, Pawel Gasior, Jing-Gang Xia, Kamal Ramzipoor, Chang Lee, Edward A Estrada, Daniell Dokko, Jenn C McGregor, Gerard B Conditt, Thomas McAndrew, Greg L Kaluza, Juan F Granada
BACKGROUND: Mechanical strength of bioresorbable scaffolds (BRS) is highly dependent on strut dimensions and polymer features. To date, the successful development of thin-walled BRS has been challenging. We compared the biomechanical behavior and vascular healing profile of a novel thin-walled (115 µm) sirolimus-eluting ultrahigh molecular weight amorphous poly-l-lactic acid-based BRS (APTITUDE, Amaranth Medical [AMA]) to Absorb (bioresorbable vascular scaffold [BVS]) using different experimental models...
July 2017: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28698292/optical-coherence-tomography-findings-in-patients-with-recanalized-coronary-thrombi-treated-with-bioresorbable-vascular-scaffolds
#11
Javier Cuesta, Marcos García-Guimaraes, Teresa Bastante, Fernando Rivero, Teresa Alvarado, Fernando Alfonso
No abstract text is available yet for this article.
July 2017: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28692483/bioresorbable-vascular-scaffolds-implication-of-very-late-scaffold-thrombosis
#12
Hiroyoshi Mori, Renu Virmani, Aloke V Finn
No abstract text is available yet for this article.
July 7, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28681058/appearance-of-bioresorbable-vascular-scaffolds-on-computed-tomography-coronary-angiography
#13
Siong Sung Wong, Gunasekaran Ramsamy
No abstract text is available yet for this article.
July 6, 2017: Singapore Medical Journal
https://www.readbyqxmd.com/read/28680011/bioresorbable-vascular-scaffolds%C3%A3-are-we-facing-a-time-of-crisis-or-one-of-breakthrough
#14
Jeehoon Kang, Jung-Kyu Han, Han-Mo Yang, Kyung Woo Park, Hyun-Jae Kang, Bon-Kwon Koo, Hyo-Soo Kim
Current 2nd-generation drug-eluting stents (DES) have dramatically improved clinical outcomes after percutaneous coronary intervention for coronary artery disease. However, DES implantation has major long-term limitations related to the permanent presence of foreign material in the coronary artery. Bioresorbable vascular scaffolds (BVS) were designed to overcome this limitation of permanent metal-based DES. However, because of immature manufacturing technology, BVS have several drawbacks, such as the thicker strut, poor deliverability, poor radio-opacity, poor radial strength, and cumbersome procedure to meet the principle of PSP (Preparation, Sizing, and Post-dilatation)...
July 6, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/28667808/coronary-artery-aneurysm-after-bioresorbable-scaffold-implantation-in-a-woman-with-an-acute-coronary-syndrome
#15
Alberto F Cereda, Paolo A Canova, Jacopo A Oreglia, Francesco S Soriano
We herein report the case of an ST-elevation myocardial infarction due to bioresorbable vascular scaffold (BRS) failure. Optical coherence tomography (OCT) revealed the exact mechanism of late BRS stent thrombosis due to an acquired coronary aneurysm related to BRS. A drug eluting OCT-guided stenting over a failed BRS in the context of an acute coronary syndrome, with the simultaneous presence of a BRS thrombosis and coronary artery aneurysm, proved to be effective.
July 2017: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/28662808/arterial-remodeling-after-bioresorbable-scaffolds-and-metallic-stents
#16
Patrick W Serruys, Yuki Katagiri, Yohei Sotomi, Yaping Zeng, Bernard Chevalier, René J van der Schaaf, Andreas Baumbach, Pieter Smits, Nicolas M van Mieghem, Antonio Bartorelli, Paul Barragan, Anthony Gershlick, Ran Kornowski, Carlos Macaya, John Ormiston, Jonathan Hill, Irene M Lang, Mohaned Egred, Jean Fajadet, Maciej Lesiak, Stephan Windecker, Robert A Byrne, Lorenz Räber, Robert-Jan van Geuns, Gary S Mintz, Yoshinobu Onuma
BACKGROUND: Although previous observational studies have documented late luminal enlargement and expansive remodeling following implantation of a bioresorbable vascular scaffold (BVS), no comparison with metallic stents has been conducted in a randomized fashion. OBJECTIVES: This study sought to compare vessel remodeling patterns after either Absorb BVS or Xience metallic drug-eluting stent (DES) implantation (Abbott Vascular, Santa Clara, California) and determine the independent predictors of remodeling...
July 4, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28659541/very-late-strut-overhang-on-coronary-angioscopy-after-bioresorbable-vascular-scaffold-implantation-in-a-clinically-stable-patient
#17
Takashi Fujimura, Tomohiro Kawasaki, Takeshi Kimura
No abstract text is available yet for this article.
June 27, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/28651349/an-autopsy-case-of-sudden-cardiac-death-due-to-in-scaffold-restenosis-and-late-scaffold-thrombosis-after-bioresorbable-vascular-scaffold-implantation-back-to-past-stent-era
#18
Kumiko Asakura, Hiroyuki Hao
No abstract text is available yet for this article.
June 22, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28649953/clinical-restenosis-and-its-predictors-after-implantation-of-everolimus-eluting-bioresorbable-vascular-scaffolds-results-from-the-gabi-r-registry
#19
Julinda Mehilli, Stephan Achenbach, Jochen Woehrle, Moritz Baquet, Thomas Riemer, Thomas Muenzel, Holger Nef, Christoph Naber, Gert Richardt, Ralf Zahn, Tommaso Gori, Till Neumann, Johannes Kastner, Axel Schmermund, Christian Hamm
AIMS: To assess clinical restenosis and its predictors after implantation bioresorbable vascular scaffolds (BVS) in everyday practice in the large scale German-Austrian ABSORB Registry (GABI-R). METHODS AND RESULTS: Between November 2013 and January 2016, 3264 patients underwent BVS implantion in 93 centers of GABI-R. At 6-month follow-up, 24 patients experienced clinically-indicated target lesion revascularization (cTLR) unrelated to BVS thrombosis (cumulative incidence 0...
June 27, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28646446/innovations-in-the-endovascular-management-of-critical-limb-ischemia-retrograde-tibiopedal-access-and-advanced-percutaneous-techniques
#20
REVIEW
Jihad A Mustapha, Larry J Diaz-Sandoval, Fadi Saab
PURPOSE OF REVIEW: Retrograde tibiopedal access and interventions have contributed to advance of endovascular techniques to treat critical limb ischemia (CLI) patients. This review encompasses the spectrum from advanced diagnostic imaging and technical therapeutic approaches for infrapopliteal occlusions, to a discussion of current standards and future directions. RECENT FINDINGS: Contemporary studies of infrapopliteal angioplasty show suboptimal short-term and 1-year clinical outcomes...
August 2017: Current Cardiology Reports
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