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bioresorbable vascular scaffold

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https://www.readbyqxmd.com/read/27916744/does-acute-coronary-syndrome-impact-on-the-incidence-of-thrombosis-after-the-implantation-of-absorb-bioresorbable-vascular-scaffold
#1
Yohei Sotomi, Yosuke Miyazaki, Carlos Colet, Taku Asano, Pannipa Suwannasom, Jan Tijssen, Robbert J de Winter, Ron Waksman, Michael J Lipinski, Yoshinobu Onuma, Patrick W Serruys
AIMS: In the drug eluting stent (DES) era, patients with acute coronary syndrome (ACS) had a higher risk of early stent thrombosis compared with stable patients. The present study evaluated whether the same is true for the bioresorbable vascular scaffold (BVS: Abbott Vascular, Santa Clara CA). METHODS AND RESULTS: We assessed the relationship between the incidence of definite/probable scaffold thrombosis (ScT) (overall ScT and early ScT) and ACS percentage with the latest publications including the most recent large randomized controlled trials...
December 6, 2016: EuroIntervention
https://www.readbyqxmd.com/read/27896897/expanded-clinical-use-of-everolimus-eluting-bioresorbable-vascular-scaffolds-for-treatment-of-coronary-artery-disease
#2
Roberto Diletti, Yuki Ishibashi, Cordula Felix, Yoshinobu Onuma, Shimpei Nakatani, Nicolas M van Mieghem, Eveliyn Regar, Marco Valgimigli, Peter P de Jaegere, Nienke van Ditzhuijzen, Jiang Ming Fam, Jurgen M R Ligthart, Mattie J Lenzen, Patrick W Serruys, Felix Zijlstra, Robert Jan van Geuns
BACKGROUND: Limited data are currently available on the performance of everolimus eluting bioresorbable vascular scaffold (BVS) for treatment of complex coronary lesions representative of daily practice. METHODS: This is a prospective, mono-center, single-arm study, reporting data after BVS implantation in patients presenting with stable, unstable angina, or non-ST segment elevation myocardial infarction caused by de novo stenotic lesions in native coronary arteries...
November 29, 2016: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/27896843/impact-of-clinical-presentation-on-early-vascular-healing-after-bioresorbable-vascular-scaffold-implantation
#3
Moritz Baquet, Christoph Brenner, Maximilian Wenzler, Madeleine Eickhoff, Jochheim David, Stefan Brunner, Hans Theiss, Steffen Massberg, Giulio Guagliumi, Julinda Mehilli
BACKGROUND: Optimal strut coverage and early vascular healing are important factors to reduce the risk of stent thrombosis. Data on early vascular healing with the new bioresorbable vascular scaffolds (BVS) are lacking. Further, healing response after BVS implantation in different clinical presentation has not been fully investigated. METHODS AND RESULTS: We assessed with optical coherence tomography (OCT) the early vascular response to BVS implantation in 26 consecutive patients presenting with acute coronary syndrome (ACS) or stable angina (SA)...
November 28, 2016: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/27896495/accuracy-of-coronary-computed-tomography-angiography-for-bioresorbable-scaffold-luminal-investigation-a-comparison-with-optical-coherence-tomography
#4
Carlos Collet, Yohei Sotomi, Rafael Cavalcante, Taku Asano, Yosuke Miyazaki, Erhan Tenekecioglu, Pieter Kistlaar, Yaping Zeng, Pannipa Suwanasson, Robbert J de Winter, Koen Nieman, Patrick W Serruys, Yoshinobu Onuma
To establish the accuracy of coronary computed tomography angiography (CTA) for in-scaffold quantitative evaluation with optical coherence tomography (OCT) as a reference. The translucent backbone of the bioresorbable scaffold allow us to evaluate non-invasively the coronary lumen with coronary CTA. In the ABSORB first-in-man studies, coronary CTA was shown to be feasible for quantitative luminal assessment. Nevertheless, a comparison with an intravascular modality with higher resolution has never been performed...
November 28, 2016: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/27891384/bioresorbable-scaffolds-current-evidences-in-the-treatment-of-coronary-artery-disease
#5
REVIEW
Bhargav Dave
Percutaneous coronary revascularization strategies have gradually progressed over a period of last few decades. The advent of newer generation drug-eluting stents has significantly improved the outcomes of Percutaneous Coronary Intervention (PCI) by substantially reducing in-stent restenosis and stent thrombosis. However, vascular inflammation, restenosis, thrombosis, and neoatherosclerosis due to the permanent presence of a metallic foreign body within the artery limit their usage in complex Coronary Artery Disease (CAD)...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27889344/malabsorption-of-a-bioresorbable-vascular-scaffold-system-leading-to-very-late-in-scaffold-restenosis-more-than-3-5-years-after-implantation-assessment-by-optical-coherence-tomography
#6
Michael Dommasch, Nikolas Langwieser, Karl-Ludwig Laugwitz, Tareq Ibrahim
No abstract text is available yet for this article.
November 17, 2016: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/27886452/bioresorbable-vascular-scaffolds-in-coronary-bifurcation-lesions-the-next-frontiers
#7
EDITORIAL
Massoud A Leesar
No abstract text is available yet for this article.
November 15, 2016: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/27884634/late-strut-fracture-within-a-partially-resorbed-bioresorbable-vascular-scaffold-a-possible-cause-of-late-scaffold-thrombosis-and-acute-coronary-syndrome
#8
Muhammad Asrar Ul Haq, Matthew Erickson, James Rankin, Alan Whelan
The Bioresorbable Vascular Scaffold (BVS, Abbott Vascular, Santa Clara, Cal, USA) is an exciting advance in percutaneous coronary intervention providing a temporary drug eluting scaffold resorbed in two to five years. We present two cases of late scaffold thrombosis associated with strut fracture during the period of resorption, at 20 and 24 months following BVS implantation. We propose luminal migration of malapposed struts following strut fracture during resorption as a potential mechanism for late scaffold thrombosis and acute coronary syndrome...
November 11, 2016: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/27876562/early-multiple-coronary-micro-aneurysms-after-bioresorbable-vascular-scaffold-implantation
#9
Fabien Picard, Philippe L L'allier, Jean-François Tanguay
Bioresorbable vascular scaffold (BVS) is a novel technology designed to overcome the long-term limitations of permanent metallic stent implantation in percutaneous coronary intervention. However, little is known about the development of coronary aneurysms after the use of BVSs, and additional experience is needed to establish the entire spectrum of complications related to the use of these emerging materials. We hereby report an unusual case of early multiple coronary artery micro aneurysms formation after BVS implantation...
September 13, 2016: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/27866134/one-year-clinical-outcomes-of-patients-treated-with-everolimus-eluting-bioresorbable-vascular-scaffolds-versus-everolimus-eluting-metallic-stents-a-propensity-score-comparison-of-patients-enrolled-in-the-absorb-extend-and-spirit-trials
#10
José de Ribamar Costa, Alexandre Abizaid, Antonio L Bartorelli, Robert Whitbourn, Nigel Jepson, Marco Perin, Clemens Steinwender, Marrianne Stuteville, Divine Ediebah, Krishnankutty Sudhir, Patrick W Serruys
AIMS: We sought to compare the outcomes of low/moderate complexity patients treated with the Absorb BVS from the ABSORB EXTEND trial with patients treated with the XIENCE everolimus-eluting stent (EES), using propensity score (PS) matching of pooled data from the SPIRIT trials (SPIRIT II, SPIRIT III, SPIRIT IV) and the XIENCE V USA trial. METHODS AND RESULTS: ABSORB EXTEND was a prospective, single-arm, open-label clinical study in which 812 patients were enrolled at 56 sites...
November 20, 2016: EuroIntervention
https://www.readbyqxmd.com/read/27865187/final-shape-of-biovascular-scaffolds-and-clinical-outcome-results-from-a-multicenter-all-comers-study-with-intravascular-imaging
#11
Bernardo Cortese, Davide Piraino, Roberto A Latini, Dennis Zavalloni, Alfonso Ielasi, Piefrancesco Agostoni, Pietro Mazzarotto, Maurizio Tespili, Romano Seregni
AIMS: Radial strength of bioresorbable vascular scaffolds (BVS) implanted in coronary arteries is still under debate. Moreover, their final shape patterns, when implanted in an all-comer, unselected population, have not yet been completely correlated with clinical outcome and should be better investigated. METHODS AND RESULTS: A multicenter collaborative analysis was performed on all consecutive patients with native coronary artery disease undergoing PCI with intravascular imaging-guided BVS implantation...
November 9, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27845999/coronary-artery-aneurysm-after-sequential-stenting-with-bioresorbable-vascular-scaffolds
#12
Valeria Paradies, Pieter C Smits
No abstract text is available yet for this article.
November 11, 2016: Coronary Artery Disease
https://www.readbyqxmd.com/read/27845998/bioresorbable-scaffolds-compared-with-everolimus-eluting-stents-for-the-treatment-of-chronic-coronary-total-occlusion-clinical-and-angiographic-results-of-a-matched-paired-comparison
#13
Christine Kugler, Sinisa Markovic, Wolfgang Rottbauer, Jochen Wöhrle
OBJECTIVES: Data on bioresorbable vascular scaffolds for recanalization of chronic total occlusions (CTOs) are limited. We compared the bioresorbable scaffold Absorb with everolimus-eluting stents for the treatment of true CTO. METHODS: After recanalization of CTO, 15 lesions treated with the bioresorbable scaffold Absorb were matched with 15 lesions receiving everolimus-eluting stent (EES) (http://www.clinicaltrials.gov NCT02162082). Match criteria were presence of diabetes mellitus, total device length and maximal device diameter...
November 11, 2016: Coronary Artery Disease
https://www.readbyqxmd.com/read/27843570/bioresorbable-vascular-scaffold-promises-and-the-fallen-child-as-king
#14
EDITORIAL
Stephane Cook, Pascal Meier
No abstract text is available yet for this article.
2016: Open Heart
https://www.readbyqxmd.com/read/27832420/disruption-of-bioresorbable-vascular-scaffold-struts-due-to-loss-of-radial-integrity-insights-from-optical-coherence-tomography
#15
Ana Rita Ramalho, João Silva Marques, Guilherme Mariano Pêgo
Strut disruption of bioresorbable vascular scaffold is a known potential concern, although uncommon when adequate lesion preparation is achieved and nominal size of the scaffold is respected. It is usually difficult to detect with angiography and/or intravascular ultrasound. Three-dimensional reconstructions of optical coherence tomography facilitates understanding of complex luminal anatomy and configuration of stent struts, providing evaluation of stent integrity immediately after deployment and therefore optimization of the complex revascularization procedure...
November 10, 2016: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/27821375/impact-of-lesion-calcification-on-angiographic-outcomes-after-absorb-everolimus-eluting-bioresorbable-vascular-scaffold-implantation-an-observation-from-the-absorb-japan-trial
#16
Masanobu Ohya, Kazushige Kadota, Yohei Sotomi, Ken Kozuma, Kengo Tanabe, Masaaki Uematsu, Tomohiro Kawasaki, Yoshihiro Morino, Tetsuya Tobaru, Koichi Nakao, Kouichi Tachibana, Koichi Kishi, Yoshisato Shibata, Shihwa Ying, Hajime Kusano, Gregg W Stone, Jeffery J Popma, Yoshinobu Onuma, Patrick W Serruys, Takeshi Kimura
AIMS: We investigated the impact of lesion calcification on angiographic outcomes after Absorb everolimus-eluting bioresorbable vascular scaffold (BVS) implantation in comparison with those after cobalt chromium everolimus-eluting stent (CoCr-EES) implantation. METHODS AND RESULTS: The present post-hoc analysis of the ABSORB Japan randomized trial compared post-procedure and 13-month angiographic outcomes between patients implanted with BVS and CoCr-EES based on the presence or absence of calcification, excluding extremely heavily calcified lesions or lesions requiring rotational atherectomy...
November 8, 2016: EuroIntervention
https://www.readbyqxmd.com/read/27806897/comparison-of-an-everolimus-eluting-bioresorbable-scaffold-with-an-everolimus-eluting-metallic-stent-for-the-treatment-of-coronary-artery-stenosis-absorb-ii-a-3-year-randomised-controlled-single-blind-multicentre-clinical-trial
#17
Patrick W Serruys, Bernard Chevalier, Yohei Sotomi, Angel Cequier, Didier Carrié, Jan J Piek, Ad J Van Boven, Marcello Dominici, Dariusz Dudek, Dougal McClean, Steffen Helqvist, Michael Haude, Sebastian Reith, Manuel de Sousa Almeida, Gianluca Campo, Andrés Iñiguez, Manel Sabaté, Stephan Windecker, Yoshinobu Onuma
BACKGROUND: No medium-term data are available on the random comparison between everolimus-eluting bioresorbable vascular scaffolds and everolimus-eluting metallic stents. The study aims to demonstrate two mechanistic properties of the bioresorbable scaffold: increase in luminal dimensions as a result of recovered vasomotion of the scaffolded vessel. METHODS: The ABSORB II trial is a prospective, randomised, active-controlled, single-blind, parallel two-group, multicentre clinical trial...
November 19, 2016: Lancet
https://www.readbyqxmd.com/read/27797464/bioresorbable-vascular-scaffolds-for-the-treatment-of-coronary-artery-disease-clinical-outcomes-from-randomized-controlled-trials
#18
David G Rizik, James B Hermiller, Dean J Kereiakes
The permanent metal prosthesis common to bare metal stents (BMS) as well as both first- and second-generation drug-eluting stents (DES) following treatment of coronary artery disease represents a long-lasting substrate for late adverse coronary events including restenosis, thrombosis, and neoatherosclerosis. Following resorbtion, bioresorbable scaffolds (BRS) may eliminate this nidus and improve late outcomes through restoration of the vessel to more normal vascular structure and function. BRS represents a single platform which incorporates the mechanical features of metallic stents to provide safe and effective revascularization, suppression of restenosis and prevention of constrictive remodeling with long-term restoration of the treated vessel to a more natural state...
November 2016: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/27797463/role-of-invasive-imaging-in-acute-and-long-term-assessment-of-bioresorbable-scaffold-technology
#19
Daniel Chamié, Hector Garcia-Garcia, Ricardo A Costa, Yoshinobu Onuma, Alexandre Abizaid, Patrick W Serruys
Fully bioresorbable scaffolds (BRS) represent a novel approach for the percutaneous treatment of coronary artery stenosis, providing temporary vessel scaffolding with drug-eluting capability during the restenosis-prone phase of the vascular healing. Beyond this initial critical period, when mechanical scaffolding support is no longer necessary, the device is bioresorbed, restoring the normal vascular physiology with the aim to eliminate the long-term safety concerns related to permanent metallic implants. Nonetheless, current BRS technology suffers from limited mechanical properties as compared to available metallic platforms, requiring careful attention to lesion preparation, accurate vessel sizing, and implantation technique...
November 2016: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/27797461/update-on-clinical-evidence-part-ii-a-summary-of-the-main-post-market-studies
#20
Corrado Tamburino, Piera Capranzano, Bruno Francaviglia, Claudia Ina Tamburino, Giovanni Longo, Davide Capodanno
Bioresorbable vascular scaffolds (BVS, Absorb, Abbott Vascular, Santa Clara, CA) received the CE mark in October 2011, and were approved by the Food and Drug Administration in July 2016. After their introduction in clinical practice a broad amount of post-marketing clinical experience with BVS has been generated so far in Europe and outside the United States. The available BVS registries differ in many aspects, including their being single-center or multicenter, single-arm or controlled, sponsored or investigator-initiated, published or presented at a large-scale international meeting...
November 2016: Catheterization and Cardiovascular Interventions
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