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bioresorbable vascular scaffold

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https://www.readbyqxmd.com/read/28646446/innovations-in-the-endovascular-management-of-critical-limb-ischemia-retrograde-tibiopedal-access-and-advanced-percutaneous-techniques
#1
REVIEW
Jihad A Mustapha, Larry J Diaz-Sandoval, Fadi Saab
PURPOSE OF REVIEW: Retrograde tibiopedal access and interventions have contributed to advance of endovascular techniques to treat critical limb ischemia (CLI) patients. This review encompasses the spectrum from advanced diagnostic imaging and technical therapeutic approaches for infrapopliteal occlusions, to a discussion of current standards and future directions. RECENT FINDINGS: Contemporary studies of infrapopliteal angioplasty show suboptimal short-term and 1-year clinical outcomes...
August 2017: Current Cardiology Reports
https://www.readbyqxmd.com/read/28644214/the-future-of-bioresorbable-vascular-scaffolds-niche-or-workhorse-devices
#2
Rony Lahoud, Stephen Ellis
No abstract text is available yet for this article.
June 21, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28643297/recommendations-for-the-use-of-bioresorbable-vascular-scaffolds-in-percutaneous-coronary-interventions-2017-revision
#3
B Everaert, J J Wykrzykowska, J Koolen, P van der Harst, P den Heijer, J P Henriques, R van der Schaaf, B de Smet, S H Hofma, R Diletti, A Weevers, J Hoorntje, P Smits, R J van Geuns
BACKGROUND: To eliminate some of the potential late limitations of permanent metallic stents, the bioresorbable coronary stents or 'bioresorbable vascular scaffolds' (BVS) have been developed. METHODS: We reviewed all currently available clinical data on BVS implantation. RESULTS: Since the 2015 position statement on the appropriateness of BVS in percutaneous coronary interventions, several large randomised trials have been presented. These have demonstrated that achieving adequate 1 and 2 year outcomes with these first-generation BVS is not straightforward...
June 22, 2017: Netherlands Heart Journal
https://www.readbyqxmd.com/read/28624381/in-scaffold-neovascularization-24-months-after-bioresorbable-vascular-scaffold-implantation-in-a-patient-with-st-segment%C3%A2-elevation-myocardial%C3%A2-infarction
#4
Mariusz Tomaniak, Janusz Kochman, Łukasz Kołtowski, Arkadiusz Pietrasik, Adam Rdzanek, Krzysztof J Filipiak, Grzegorz Opolski, Evelyn Regar
No abstract text is available yet for this article.
June 7, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28612280/mid-term-and-long-term-safety-and-efficacy-of-bioresorbable-vascular-scaffolds-versus-metallic-everolimus-eluting-stents-in-coronary-artery-disease-a%C3%A2-weighted-meta-analysis-of-seven-randomised-controlled-trials-including-5577-patients
#5
J Elias, I M van Dongen, R P Kraak, R Y G Tijssen, B E P M Claessen, J G P Tijssen, R J de Winter, J J Piek, J J Wykrzykowska, J P S Henriques
AIMS: Mid- and long-term safety and efficacy of the Absorb bioresorbable vascular scaffold (BVS) have been studied in randomised trials; however, most were not individually powered for clinical endpoints. We performed a weighted meta-analysis comparing mid- and long-term outcomes in patients treated with the BVS compared with the Xience metallic stent. METHODS AND RESULTS: Randomised trials comparing the BVS and Xience were identified by searching MEDLINE, EMBASE and conference abstracts...
June 13, 2017: Netherlands Heart Journal
https://www.readbyqxmd.com/read/28600401/comparison-of-a-drug-free-early-programmed-dismantling-pdlla-bioresorbable-scaffold-and-a-metallic-stent-in-a-porcine-coronary-artery-model-at-3-year-follow-up
#6
Kazuyuki Yahagi, Yi Yang, Sho Torii, Johanne Mensah, Roseann M White, Marion Mathieu, Erica Pacheco, Masataka Nakano, Abdul Barakat, Tahmer Sharkawi, Michel Vert, Michael Joner, Aloke V Finn, Renu Virmani, Antoine Lafont
BACKGROUND: Arterial Remodeling Technologies bioresorbable scaffold (ART-BRS), composed of l- and d-lactyl units without drug, has shown its safety in a porcine coronary model at 6 months. However, long-term performance remains unknown. The aim of this study was to evaluate the ART-BRS compared to a bare metal stent (BMS) in a healthy porcine coronary model for up to 3 years. METHODS AND RESULTS: Eighty-two ART-BRS and 66 BMS were implanted in 64 Yucatan swine, and animals were euthanatized at intervals of 1, 3, 6, 9, 12, 18, 24, and 36 months to determine the vascular response using quantitative coronary angiography, optical coherence tomography, light and scanning electron microscopy, and molecular weight analysis...
June 9, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28597206/effect-of-strut-distribution-on-neointimal-coverage-of-everolimus-eluting-bioresorbable-scaffolds-an-optical-coherence-tomography-study
#7
Takao Sato, John Jose, Abdelhakim Allai, Mohamed El-Mawardy, Ralph Tölg, Gert Richardt, Mohamed Abdel-Wahab
The thick struts of bioresorbable vascular scaffolds (BRS) are associated with changes in wall shear stress and contribute to neointimal proliferation. We aimed to evaluate the relationship between the BRS strut distribution and the neointimal proliferation. 50 lesions underwent optical coherence tomography, 12 months after BRS implantation. Scaffold area and neointimal thickness were evaluated in each cross-sectional area (CSA). Scaffold eccentricity was defined as follows: (maximum diameter - minimum diameter) × 100/maximum diameter...
June 9, 2017: Journal of Thrombosis and Thrombolysis
https://www.readbyqxmd.com/read/28592227/long-term-outcome-of-bioresorbable-vascular-scaffolds-for-the-treatment-of-coronary-artery-disease-a-meta-analysis-of-rcts
#8
Alberto Polimeni, Remzi Anadol, Thomas Münzel, Ciro Indolfi, Salvatore De Rosa, Tommaso Gori
BACKGROUND: Coronary bioresorbable scaffolds (BRS) were developed to overcome the limitations of standard metallic stents, especially to address late events after percutaneous coronary interventions. The aim of this meta-analysis was to evaluate the efficacy and safety of BRS, compared with Everolimus-eluting stents (EES), using the data available from randomized trials, with a focus on long-term outcomes. METHODS: Published randomized trials comparing BRS to EES for the treatment of coronary artery disease were searched for within PubMed, Cochrane Library and Scopus electronic databases up to April 4th 2017...
June 7, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28591063/a-new-technique-for-lipid-core-plaque-detection-by-optical-coherence-tomography-for-prevention-of-peri-procedural-myocardial-infarction-a-case-report
#9
Yongcheol Kim, Muthukaruppan Gnanadesigan, Gijs van Soest, Thomas W Johnson
RATIONALE: Percutaneous coronary intervention (PCI) provides effective revascularization of atherosclerotic coronary arteries but the invasive nature of treatment can result in complications. PATIENT CONCERNS: A 53-year old man underwent coronary angiography due to chest pain with minimal ST-segment elevation in the inferior leads of the electrocardiogram. DIAGNOSIS: We proceeded directly to coronary angiography and delineated a moderate stenosis with haziness in the mid right coronary artery (RCA)...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28590249/difference-in-hemodynamic-microenvironment-in-vessels-scaffolded-with-absorb-bvs-and-mirage-brms-insights-from-a-pre-clinical-endothelial-shear-stress-study
#10
Erhan Tenekecioglu, Ryo Torii, Christos Bourantas, Yohei Sotomi, Rafael Cavalcante, Yaping Zeng, Carlos Collet, Tom Crake, Pannipa Suwannasom, Yoshinobu Onuma, Patrick W Serruys
AIMS: In silico studies have provided robust evidence that stent design affects local hemodynamic forces, which appear as a major determinant of clinical outcomes following stent implantation. However, implications of different stent/scaffold configurations on local hemodynamic forces have not yet been investigated in vivo in a comparative fashion. METHOD AND RESULTS: Eight healthy mini pigs were implanted with six Absorb everolimus-eluting Bioresorbable Vascular Scaffolds (Absorb BVS) and five Mirage sirolimus-eluting Bioresorbable Microfiber Scaffolds (Mirage BRMS)...
June 6, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28582032/design-principles-of-bioresorbable-polymeric-scaffolds
#11
REVIEW
Mary Beth Kossuth, Laura E L Perkins, Richard J Rapoza
The concept for a bioresorbable vascular scaffold combines the best features of the first 3 generations of percutaneous coronary intervention (namely), balloon angioplasty, bare metallic stents, and drug-eluting stents, into a single device. The principles of operation of a BRS follow 3 phases of functionality that reflect the different physiologic requirements over time; revascularization, restoration, and resorption. Most BRS designs make use of the continuum of hydrolytic degradation in aliphatic polyesters, such as poly(l-lactide), in which molecular weight, strength, and mass decrease progressively in 3 distinct stages, consistent with the in vivo requirements of each performance phase...
July 2016: Interventional cardiology clinics
https://www.readbyqxmd.com/read/28579240/first-observation-of-a-golden-tube-after-complete-resorption-of-a-bioresorbable-vascular-scaffold-in-a-transplanted-patient-with-cardiac-allograft-vasculopathy
#12
Flavio Ribichini, Roberto Scarsini, Claudia Zanetti, Gabriele Pesarini
No abstract text is available yet for this article.
May 25, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28579092/coronary-artery-aneurysm-formation-following-implantation-of-a-bioresorbable-vascular-scaffold-for-in-stent-restenosis
#13
Marcos García-Guimaraes, Javier Cuesta, Teresa Alvarado, Fernando Rivero, Teresa Bastante, Amparo Benedicto, Fernando Alfonso
Coronary artery aneurysm (CAA) formation is a rare complication of coronary intervention that may develop after implantation of bare-metal or drug-eluting stents. The etiology of this entity appears to be multifactorial and its prognosis is poorly understood, but it has been associated with an increased risk of stent thrombosis. To date few cases of CAAs related to bioresorbable vascular scaffold (BVS) implantation have been reported, and the development of CAA after BVS implantation for the treatment of in-stent restenosis (ISR) has not been previously described...
May 31, 2017: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/28576627/comparison-of-everolimus-and-biolimus-eluting-coronary-stents-with-everolimus-eluting-bioresorbable-vascular-scaffolds-two-year-clinical-outcomes-of-the-everbio-ii-trial
#14
Diego Arroyo, Gregoire Gendre, Sara Schukraft, Zacharenia Kallinikou, Olivier Müller, Gérard Baeriswyl, Jean-Christophe Stauffer, Jean-Jacques Goy, Mario Togni, Stéphane Cook, Serban Puricel
BACKGROUND: Data from randomized controlled trials have shown that the ABSORB BVS is non-inferior to Cobalt Chromium everolimus-eluting stents at 2years. METHODS & RESULTS: The EVERBIO II trial (Comparison of Everolimus- and Biolimus-Eluting Coronary Stents with Everolimus-Eluting Bioresorbable Vascular Scaffold) is a single-center, assessor-blind, randomized controlled trial enrolling 240 patients with an allocation ration of 1:1:1 conducted at University and Hospital Fribourg, Switzerland...
May 12, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28574901/first-in-man-demonstration-of-complete-bioresorbable-vascular-scaffold-resorption-after-treatment-of-in-stent-restenosis
#15
Elisabetta Moscarella, Alfonso Ielasi, Bernardo Cortese, Maria C De Angelis, Attilio Varricchio
No abstract text is available yet for this article.
June 1, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28568564/long-term-clinical-results-of-bioresorbable-absorb-scaffolds-using-the-psp-technique-in-patients-with-and-without-diabetes
#16
Sinisa Markovic, Christine Kugler, Wolfgang Rottbauer, Jochen Wöhrle
OBJECTIVES: We evaluated clinical results up to 36 months after implantation of Absorb BVS using PSP-technique and compared the outcome of patients with and without diabetes mellitus. BACKGROUND: Absorb II demonstrated that interventional treatment of coronary artery disease with bioresorbable vascular scaffolds (BVS) without proper PSP-technique (pre-dilation, proper sizing, and post-dilation) is associated with an increased thrombotic risk, even in simple lesions...
June 1, 2017: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/28562185/hypoxia-biomimicry-to-enhance-monetite-bone-defect-repair
#17
Justin Drager, Jose Luis Ramirez-GarciaLuna, Abhishek Kumar, Uwe Gbureck, Edward J Harvey, Jake Barralet
Tissue hypoxia is a critical driving force for angiogenic and osteogenic responses in bone regeneration and is, at least partly, under the control of the Hypoxia Inducible Factor-1α (HIF-1α) pathway. Recently, the widely used iron chelator Deferoxamine (DFO) has been found to elevate HIF-1α levels independent of oxygen concentrations, thereby, creating an otherwise normal environment that mimics the hypoxic state. This has the potential to augment the biological properties of inorganic scaffolds without the need of recombinant growth factors...
May 31, 2017: Tissue Engineering. Part A
https://www.readbyqxmd.com/read/28559655/everolimus-eluting-bioresorbable-vascular-scaffold-in-real-world-practice-a-single-center-experience
#18
Huai-Wen Liang, Hsien-Li Kao, Yen-Hung Lin, Juey-Jen Hwang, Mao-Shin Lin, Fu-Tien Chiang, Chii-Ming Lee, Chih-Fan Yeh, Tzung-Dau Wang, Cho-Kai Wu, Lian-Yu Lin, Chia-Ti Tsai, Ying-Hsien Chen
BACKGROUND: Drug-eluting stents are widely used in coronary artery intervention. However, vessel caging and very late thrombotic events are of persistent and substantial concern. Bioresorbable vascular scaffolds (BVS) were developed to deliver vascular reparative therapy, by eliminating permanent mechanical restraint. However, data regarding its clinical performance is lacking. METHODS: After the BVS implantation procedure received national approval in May 2014, patients receiving BVS implantation until November 2014 in National Taiwan University Hospital (NTUH) were enrolled...
May 2017: Acta Cardiologica Sinica
https://www.readbyqxmd.com/read/28559495/temporal-trends-in-adverse-events-after-everolimus-eluting-bioresorbable-vascular-scaffold-versus-everolimus-eluting-metallic-stent-implantation-a-meta-analysis-of-randomized-controlled-trials
#19
Rocco A Montone, Giampaolo Niccoli, Federico De Marco, Silvia Minelli, Fabrizio D'Ascenzo, Luca Testa, Francesco Bedogni, Filippo Crea
BACKGROUND: Bioresorbable coronary stents have been introduced into clinical practice to improve the outcomes of patients treated with percutaneous coronary intervention. The everolimus-eluting bioresorbable vascular scaffold (BVS) is the most studied of these stent platforms; however, recent trials comparing BVS with everolimus-eluting metallic stents (EES) raised concerns about BVS safety. We aimed to assess the efficacy and safety of BVS versus EES in patients undergoing percutaneous coronary intervention...
May 30, 2017: Circulation
https://www.readbyqxmd.com/read/28527768/randomized-comparison-of-absorb-bioresorbable-vascular-scaffold-and-mirage-microfiber-sirolimus-eluting-scaffold-using-multimodality-imaging
#20
Erhan Tenekecioglu, Patrick W Serruys, Yoshinobu Onuma, Ricardo Costa, Daniel Chamié, Yohei Sotomi, Ting-Bin Yu, Alexander Abizaid, Houng-Bang Liew, Teguh Santoso
OBJECTIVES: The primary objective of this study was to evaluate the safety and effectiveness of the Mirage bioresorbable microfiber sirolimus-eluting scaffold compared with the Absorb bioresorbable vascular scaffold in the treatment of stenotic target lesions located in native coronary arteries, ranging from ≥2.25 to ≤4.0 mm in diameter. Secondary objectives were to establish the medium-term safety, effectiveness, and performance of the Mirage device. BACKGROUND: The current generation of bioresorbable scaffolds has several limitations, such as thick square struts with large footprints that preclude their deep embedment into the vessel wall, resulting in protrusion into the lumen with microdisturbance of flow...
May 11, 2017: JACC. Cardiovascular Interventions
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