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Chronic lymphocytic thyroiditis

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https://www.readbyqxmd.com/read/27878772/chronic-lymphocytic-thyroiditis-does-not-influence-the-risk-of-recurrence-in-patients-with-papillary-thyroid-carcinoma-and-excellent-response-to-initial-therapy
#1
Marina S Carvalho, Pedro W Rosario, Gabriela F Mourão, Maria R Calsolari
BACKGROUND: This study evaluated the recurrence in patients with papillary thyroid cancer and an excellent response to initial therapy, comparing those with and without chronic lymphocytic thyroiditis. METHODS: This was a prospective study. Patients who met the following criteria were selected: diagnosis of papillary thyroid cancer; submitted to total thyroidectomy followed or not by ablation with (131)I; and neck ultrasonography without abnormalities, nonstimulated thyroglobulina (Tg) ≤0...
November 23, 2016: Endocrine
https://www.readbyqxmd.com/read/27756987/cytomorphologic-spectrum-of-lymphocytic-thyroiditis-and-correlation-between-cytological-grading-and-biochemical-parameters
#2
K R Anila, Nileena Nayak, K Jayasree
INTRODUCTION: Chronic lymphocytic thyroiditis [Hashimoto thyroiditis (HT)] is a common thyroid lesion diagnosed on fine-needle aspiration cytology (FNAC). Apart from FNAC, various other parameters, such as clinical features, ultrasonographic findings, antithyroid antibody levels, hormone profiles, and radionuclide thyroid scan, are also taken into consideration in making a diagnosis of HT. AIMS: To grade lymphocytic thyroiditis based on the cytomorphology and to correlate the cytological grades with the levels of antithyroid peroxidase antibody (ATPO), antithyroglobulin antibody (ATG), and thyroid stimulating hormone (TSH)...
July 2016: Journal of Cytology
https://www.readbyqxmd.com/read/27682712/an-update-on-thyroid-associated-ophthalmopathy-in-children-and-adolescents
#3
Justyna Szczapa-Jagustyn, Anna Gotz-Więckowska, Jarosław Kocięcki
BACKGROUND: Risk of developing thyroid-associated ophthalmopathy (TAO) in children and adolescents is similar or may be even slightly higher than in adults. The aim of this article is to review and summarize current knowledge regarding diagnostic and therapeutic measures in pediatric TAO. CONTENT: MEDLINE and EMBASE papers were searched using the terms 'pediatric Graves' ophthalmopathy' 'pediatric Graves' orbitopathy', 'thyroid-associated ophthalmopathy in childhood and adolescence' from the year 1970 to December 2015...
October 1, 2016: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/27645473/the-incidence-and-risk-factors-for-central-lymph-node-metastasis-in-cn0-papillary-thyroid-microcarcinoma-a-meta-analysis
#4
REVIEW
Liang-Sen Liu, Jia Liang, Jun-Hong Li, Xue Liu, Li Jiang, Jian-Xiong Long, Yue-Ming Jiang, Zhi-Xiao Wei
Although there have been many studies identifying clinical and pathologic factors that may predict central lymph node metastases (CLNM) in papillary thyroid microcarcinoma (PTMC) patients without clinically cervical lymph node metastasis (cN0), the results were inconsistent. And whether prophylactic central lymph node dissection (pCLND) should be performed in cN0 PTMC remains controversial. The EMBASE, PubMed, MEDLINE and the Cochrane Library were searched until Oct 2015 to identify relevant studies. Primary outcomes were clinical and pathologic factors for CLNM...
September 19, 2016: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/27560798/elevated-neutrophil-lymphocyte-ratio-in-patients-with-euthyroid-chronic-autoimmune-thyreotidis
#5
Havva Keskin, Y Kaya, K Cadirci, C Kucur, E Ziypak, E Simsek, H Gozcu, S Arikan, A Carlioglu
OBJECTIVE: The neutrophil-lymphocyte ratio (NLR), determined from peripheral blood, is accepted as an available and practical indicator of the systemic inflammation. In this study, we aimed to determine whether the NLR was higher in euthyroid chronic autoimmune thyreotidis (CAT) patients compared to a healthy control group. METHODS: A total of 112 patients were enrolled in this study, including 59 patients with euthyroid CAT on any form of therapy and 53 healthy controls...
July 2016: Endocrine Regulations
https://www.readbyqxmd.com/read/27386325/fine-needle-aspiration-cytology-guided-by-ultrasound-in-the-diagnosis-of-subcentimetre-thyroid-nodules
#6
Cheng Li, Weiwei Zhan, Fang Yi, Bin Zheng, Yaqin Zhou, Ran Zhao, Yi Jia
BACKGROUND: This study aimed to investigate the value of fine needle aspiration biopsy (FNAB) under ultrasound guidance in diagnosis of thyroid nodules. In a retrospective analysis of FNAB in 1050 cases of patients with 1100 nodules, patients were divided according to the maximum diameter of their nodules into two groups: >1.0 and ≤1.0 cm. The ultrasound-guided FNAB cytology results were compared between two groups. RESULTS: Ultrasound findings showed that among 1100 thyroid nodules, 547 were highly suspicious, 358 were moderately, 175 were low, and 19 were very low...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27347131/multidetector-computed-tomography-analysis-of-benign-and-malignant-nodules-in-patients-with-chronic-lymphocytic-thyroiditis
#7
Caisong Zhu, Wei Liu, Jun Yang, Jing Yang, Kangwei Shao, Lixin Yuan, Hairong Chen, Wei Lu, Ying Zhu
The aim of the present study was to compare the multidetector computed tomography (MDCT) features of benign and malignant nodules in patients with chronic lymphocytic thyroiditis (CLT). MDCT findings, including the size, solid percentage, calcification, margin, capsule, anteroposterior-transverse diameter ratio as well as the mode and the degree of enhancement of 137 thyroid nodules in 127 CLT cases were retrospectively analyzed. Furthermore, the correlation between MDCT findings and pathological results combined with the CT perfusion imaging was analyzed for the differences between benign and malignant nodules...
July 2016: Oncology Letters
https://www.readbyqxmd.com/read/27336835/histogram-and-gray-level-co-occurrence-matrix-on-gray-scale-ultrasound-images-for-diagnosing-lymphocytic-thyroiditis
#8
Young Gyung Shin, Jaeheung Yoo, Hyeong Ju Kwon, Jung Hwa Hong, Hye Sun Lee, Jung Hyun Yoon, Eun-Kyung Kim, Hee Jung Moon, Kyunghwa Han, Jin Young Kwak
The objective of the study was to evaluate whether texture analysis using histogram and gray level co-occurrence matrix (GLCM) parameters can help clinicians diagnose lymphocytic thyroiditis (LT) and differentiate LT according to pathologic grade. The background thyroid pathology of 441 patients was classified into no evidence of LT, chronic LT (CLT), and Hashimoto's thyroiditis (HT). Histogram and GLCM parameters were extracted from the regions of interest on ultrasound. The diagnostic performances of the parameters for diagnosing and differentiating LT were calculated...
August 1, 2016: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/27259353/incidence-of-thyroid-diseases-in-zhejiang-province-china-after-15-years-of-salt-iodization
#9
Fang Gu, Gangqiang Ding, Xiaoming Lou, Xiaofeng Wang, Zhe Mo, Wenming Zhu, Jinshui Zhou, Guangming Mao
Thyroid diseases(TD) can be induced by either deficient or excessive iodine intake. Universal Salt Iodization(USI) program has been implemented in China since 1995, to prevent iodine deficiency disorders (IDD). To evaluate the current conditions of TD and the role of USI, a multi-stage stratified random sampling scheme was used to perform a cross-sectional survey on the incidence of TD among participants in 6600 households in Zhejiang Province, a coastal area in China. Iodine nutrition status of the population was assessed by dietary iodine intake recall and urinary iodine concentration (UIC) of the participants, and TD were diagnosed by thyroid ultrasonography for 15122 participants and for 5873 participants by serum criteria for thyroid function(fT3, fT4, TSH, TRAb, TgAb, TPOAb; see Introduction for abbreviations)...
July 2016: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/27094616/the-rate-and-clinical-significance-of-incidental-thyroid-uptake-as-detected-by-gallium-68-dotatate-positron-emission-tomography-computed-tomography
#10
Pavel Nockel, Corina Millo, Xavier Keutgen, Joanna Klubo-Gwiezdzinska, Jasmine Shell, Dhaval Patel, Naris Nilubol, Peter Herscovitch, Samira M Sadowski, Electron Kebebew
BACKGROUND: Gallium-68 (Ga-68) DOTATATE is a radiolabeled peptide-imaging modality that targets the somatostatin receptor (SSTR), especially subtype 2 (SSTR2). Benign and malignant thyroid tumors have been observed to express SSTR. The aim of this study was to evaluate the frequency and clinical significance of incidental atypical thyroid uptake as detected by Ga-68 DOTATATE positron emission tomography/computed tomography (PET/CT). METHODS: A retrospective analysis was conducted of a prospective study in which 237 patients underwent Ga-68 DOTATATE PET/CT as part of a work-up for metastatic and unknown primary neuroendocrine tumors...
June 2016: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/27075321/predictive-factors-for-lymph-node-metastasis-in-papillary-thyroid-microcarcinoma
#11
Seo Ki Kim, Inhye Park, Jung-Woo Woo, Jun Ho Lee, Jun-Ho Choe, Jung-Han Kim, Jee Soo Kim
BACKGROUND: Because lymph node (LN) metastasis has been proven to be a predictor for locoregional recurrence (LRR) in papillary thyroid microcarcinoma (PTMC), better knowledge about the predictors for LN metastasis in PTMC is required. METHODS: We retrospectively reviewed 5656 PTMC patients who underwent total thyroidectomy and central neck dissection and/or lateral neck dissection between January 1997 and June 2015. RESULTS: Male gender (adjusted odds ratio [OR] 2...
September 2016: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/26998721/cancer-risks-in-u-s-radiologic-technologists-working-with-fluoroscopically-guided-interventional-procedures-1994-2008
#12
Preetha Rajaraman, Michele M Doody, Chu Ling Yu, Dale L Preston, Jeremy S Miller, Alice J Sigurdson, D Michal Freedman, Bruce H Alexander, Mark P Little, Donald L Miller, Martha S Linet
OBJECTIVE: The purpose of this study was to examine risks of cancer incidence and mortality among U.S. radiation technologists performing or assisting with fluoroscopically guided interventional procedures. SUBJECTS AND METHODS: A nationwide prospective cohort of 90,957 radiologic technologists, who responded to a 1994-1998 survey that collected information on whether they had ever worked with fluoroscopically guided interventional procedures, was followed through completion of a subsequent cohort survey during 2003-2005 (for cancer incidence) or December 31, 2008 (for cancer mortality)...
May 2016: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/26994869/clinical-challenge-an-orbital-hickam-s-dictum
#13
Michelle E Wilson, Sarah Thornton, Ann P Murchison, Jurij R Bilyk
A 53-year-old man with hyperthyroidism presented with asymmetric proptosis and diplopia. Thyroid-stimulating immunoglobulin was elevated, suggesting active thyroid eye disease. Imaging of the orbits revealed enlargement of the extraocular muscles, including irregular enlargement of the left lateral rectus muscle. Biopsy of the lateral rectus muscle demonstrated infiltration of the muscle with Bcl-2 positive B lymphocytes consistent with chronic lymphocytic leukemia (CLL). Evaluation for systemic lymphoproliferative disease was negative...
March 17, 2016: Survey of Ophthalmology
https://www.readbyqxmd.com/read/26888268/-raise-awareness-of-igg4-relative-ocular-disease
#14
Shihui Wei, Hongyang Li
Purpose IgG4-related ocular disease is a chronic systemic disease with lymphocyte abnormal. The lacrimal glands, extraocular muscles and infraorbital nerve were often involved which was often the first symptom of systemic disease. While ophthalmologists did not know this disease well. They usually misdiagnosed it as idiopathic inflammatory pseudotumor, thyroid-associated ophthalmopathy etc, which resulted in delayed treatments. Here pathogenesis, clinical features and treatment methods of IgG4-relative ocular disease were described in order to improve awareness of this ocular disease, reduce clinical misdiagnosis, improve disease prognosis and standardized treatment...
December 2015: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/26806192/ultrasonographic-features-and-clinical-characteristics-of-warthin-like-variant-of-papillary-thyroid-carcinoma
#15
Ga Ram Kim, Jung Hee Shin, Soo Yeon Hahn, Eun Young Ko, Young Lyun Oh
Warthin-like variant of papillary thyroid carcinoma (WVPTC) is a rare entity recently characterized. We evaluated ultrasonographic (US) features and clinical characteristics of WVPTC. Nine patients were diagnosed with WVPTC through surgery in our institution from May 2005 to January 2015. Eight of nine patients had available preoperative US images. A retrospective review of the US and clinical characteristics was performed. WVPTC compromised of 0.06% of 14,071 PTCs surgically confirmed. A mean age of nine patients was 53...
April 25, 2016: Endocrine Journal
https://www.readbyqxmd.com/read/26711636/clinical-analysis-of-familial-nonmedullary-thyroid-carcinoma
#16
Qiang Zhang, Shuai Yang, Xian-ying Meng, Guang Chen, Ren-zhu Pang
OBJECTIVE: To analyze the clinical characteristics of familial nonmedullary thyroid carcinoma (FNMTC), in order to provide evidence for early diagnosis and treatment. METHODS: We retrospectively investigated the inpatients between September 2006 and September 2013 in the First Bethune Hospital of Jilin University, in which 78 patients with FNMTC from 31 families were analyzed by a comparison with 3445 control cases from the patients with sporadic nonmedullary thyroid carcinoma (SNMTC)...
March 2016: World Journal of Surgery
https://www.readbyqxmd.com/read/26708864/coexistence-of-chronic-lymphocytic-thyroiditis-and-papillary-thyroid-carcinoma-impact-on-presentation-management-and-outcome
#17
C Dobrinja, P Makovac, M Pastoricchio, T Cipolat Mis, S Bernardi, B Fabris, L Piscopello, N de Manzini
BACKGROUND: The association between chronic lymphocytic thyroiditis (CLT) and papillary thyroid carcinoma (PTC) has been investigated for several years from different perspectives. In spite of that, there were only few attempts to design a common frame of references to understand the complex mutual interactions between the various pathways of inflammatory response and of thyroid tumor induction and progression. This study compares two independent groups of patients aiming to determine the frequency and the prognostic significance of CLT in patients with PTC...
April 2016: International Journal of Surgery
https://www.readbyqxmd.com/read/26693459/thyroiditis-a-clinico-cytomorphological-study-with-a-reference-to-the-ethnic-groups-of-northeast-regions-of-india
#18
Abhijit Kalita, Ronica Baruah
Definite clinico-cytological criterion is outlined for thyroid lesions. Fine needle aspiration cytology (FNAC) makes it easier to segregate cases of thyroiditis (Chronic lymphocytic thyroiditis/Hashimoto's thyroiditis-CLT/HT, and subacute thyroiditis-SAT) from other benign and malignant lesions of thyroid. The study was done for a period of 5½ years at a diagnostic centre in Guwahati. Patients underwent FNAC and smears were studied for cytomorphology. A correlation with clinical features and thyroid function, including antithyroid antibody estimation, was done, wherever possible...
December 2015: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/26614433/wnt5a-and-ror2-expression-associate-with-the-disease-progress-of-primary-thyroid-lymphoma
#19
Lei Wang, Dong Yang, Ying-Hou Wang, Xi Li, Hong-Ming Gao, Jun-Yuan Lv, Lei Wang, Shi-Jie Xin
Primary thyroid lymphoma (PTL) is a rare malignant thyroid tumor; its pathogenesis is closely related to chronic lymphocytic thyroiditis. The different pathological subtypes and stages of PTL have distinct clinical characteristics and prognosis, but the specific reasons are not clear. Wnt5a is a representative protein of non-canonical Wnt signaling. It plays an important role in many different types of tumors. This study is to explore the changes of Wnt5a and its receptor Ror2 in PTL development process and the clinical significance of their represent...
May 2016: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/26608372/wnt5a-and-ror2-expression-associate-with-the-disease-progress-of-primary-thyroid-lymphoma
#20
Lei Wang, Dong Yang, Ying-Hou Wang, Xi Li, Hong-Ming Gao, Jun-Yuan Lv, Lei Wang, Shi-Jie Xin
Primary thyroid lymphoma (PTL) is a rare malignant thyroid tumor; its pathogenesis is closely related to chronic lymphocytic thyroiditis. The different pathological subtypes and stages of PTL have distinct clinical characteristics and prognosis, but the specific reasons are not clear. Wnt5a is a representative protein of non-canonical Wnt signaling. It plays an important role in many different types of tumors. This study is to explore the changes of Wnt5a and its receptor Ror2 in PTL development process and the clinical significance of their represent...
May 2016: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
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