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https://www.readbyqxmd.com/read/28818316/predicting-in-hospital-mortality-in-patients-with-acute-coronary-syndrome-in-china
#1
Yong Peng, Xin Du, Kris D Rogers, Yangfeng Wu, Runlin Gao, Anushka Patel
Currently available risk scores (RSs) were derived from populations with very few participants from China. We aimed to develop an RS based on data from patients with acute coronary syndrome in China and to compare its performance with the commonly promoted Global Registry of Acute Coronary Events (GRACE) RS. Clinical Pathways for Acute Coronary Syndromes-Phase 2 was a trial of a quality improvement intervention in China. Patients recruited from 75 hospitals from October 2007 to August 2010 were divided into training and validation sets based on immediate or delayed implementation...
July 19, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28817299/how-do-medicare-advantage-beneficiary-payments-vary-with-tenure
#2
Paul D Jacobs, Eamon Molloy
OBJECTIVES: To compare how premiums and expected out-of-pocket medical costs (OOPC) vary with the length of time Medicare Advantage (MA) beneficiaries have been enrolled in their plans. STUDY DESIGN: Descriptive and fixed effects regression analyses. METHODS: Using linked administrative enrollment and plan data, we compared the costs of the MA plans that beneficiaries chose with the costs of other plans available to them. We show predicted values adjusted for age, gender, race/ethnicity, disability, individual health risk, presence of mental health diagnoses, health plan quality, relative size of the plan's provider network, and the number of years continuously enrolled in the same plan...
June 2017: American Journal of Managed Care
https://www.readbyqxmd.com/read/28813555/analysis-of-item-level-bias-in-the-bayley-iii-language-subscales-the-validity-and-utility-of-standardized-language-assessment-in-a-multilingual-setting
#3
Shaun K Y Goh, Elaine K H Tham, Iliana Magiati, Litwee Sim, Shamini Sanmugam, Anqi Qiu, Mary L Daniel, Birit F P Broekman, Anne Rifkin-Graboi
Purpose: The purpose of this study was to improve standardized language assessments among bilingual toddlers by investigating and removing the effects of bias due to unfamiliarity with cultural norms or a distributed language system. Method: The Expressive and Receptive Bayley-III language scales were adapted for use in a multilingual country (Singapore). Differential item functioning (DIF) was applied to data from 459 two-year-olds without atypical language development...
August 15, 2017: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/28812957/examining-gender-bias-in-the-feedback-shared-with-family-medicine-residents
#4
Chantal Loeppky, Oksana Babenko, Shelley Ross
OBJECTIVES: Competency-based education places increasing emphasis on formative feedback to learners as part of the assessment process. We wished to determine if gender bias was present in the feedback shared with post-graduate medical trainees (residents) in a two-year family medicine residency program at a Canadian university. METHODS: We performed secondary data analyses of documented feedback (FieldNotes) extracted from the Competency-Based Achievement System database...
August 16, 2017: Education for Primary Care
https://www.readbyqxmd.com/read/28812371/two-physical-activity-measures-paffenbarger-physical-activity-questionnaire-versus-aerobics-center-longitudinal-study-as-predictors-of-adult-onset-type-2-diabetes-in-a-follow-up-study
#5
Serena Tonstad, Patti Herring, Jerry Lee, Jennifer Duxbury Johnson
PURPOSE: To compare 2 self-report methods of measuring weekly minutes of physical activity based on the Aerobics Center Longitudinal Study (ACLS) questionnaire and question 6 of the Paffenbarger Physical Activity Questionnaire (PPAQ) to determine the better predictor of adult-onset type 2 diabetes mellitus (T2DM). DESIGN: An observational, prospective study. SETTING: Survey data from the Adventist Health Study-2 (AHS-2) collected between 2002 and 2006 (baseline) and the Psychosocial Manifestations of Religion Sub-Study (PsyMRS), an AHS-2 subset collected 1 to 4 years later...
January 1, 2017: American Journal of Health Promotion: AJHP
https://www.readbyqxmd.com/read/28797893/genetic-association-of-telomere-length-with-hepatocellular-carcinoma-risk-a-mendelian-randomization-analysis
#6
Yue Cheng, Chengxiao Yu, Mingtao Huang, Fangzhi Du, Ci Song, Zijian Ma, Xiangjun Zhai, Yuan Yang, Jibin Liu, Jin-Xin Bei, Weihua Jia, Guangfu Jin, Shengping Li, Weiping Zhou, Jianjun Liu, Juncheng Dai, Zhibin Hu
BACKGROUND: Observational studies show an association between telomere length and Hepatocellular carcinoma (HCC) risk, but the relationship is controversial. Particularly, it remains unclear whether the association is due to confounding or biases inherent in conventional epidemiological studies. Here, we applied Mendelian randomization approach to evaluate whether telomere length is causally associated with HCC risk. METHODS: Individual-level data were from HBV-related HCC Genome-wide association studies (1,538 HBV positive HCC patients and 1,465 HBV positive controls)...
August 7, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28797237/validity-of-the-global-physical-activity-questionnaire-gpaq-in-bangladesh
#7
Shirin Jahan Mumu, Liaquat Ali, Anthony Barnett, Dafna Merom
BACKGROUND: Feasible and cost-effective as well as population specific instruments for monitoring physical activity (PA) levels are needed for the management and prevention of non-communicable diseases. The WHO-endorsed Global Physical Activity Questionnaire (GPAQ) has been widely used in developing countries, but the evidence base for its validity, particularly for rural populations, is still limited. The aim of the study was to validate GPAQ among rural and urban residents in Bangladesh...
August 10, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28795307/sex-symptom-severity-and-quality-of-life-in-rheumatology
#8
REVIEW
Marco Krasselt, Christoph Baerwald
Inflammatory rheumatic diseases such as rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) show a striking female predominance ranging from 3:1 in RA up to 9:1 in SLE. The background for those gender bias is not fully understood yet, but seems to be the result of a complex interaction between sex hormones, (epi-)genetics, and possibly even the composition of gut microbiota. Moreover, time of disease onset, the clinical phenotype including co-morbidities as well as the course of the diseases during life differ between genders...
August 9, 2017: Clinical Reviews in Allergy & Immunology
https://www.readbyqxmd.com/read/28794278/research-papers-gender-bias-and-peer-review
#9
EDITORIAL
Rick Battarbee
No abstract text is available yet for this article.
August 2017: Biology Letters
https://www.readbyqxmd.com/read/28792940/differences-in-words-used-to-describe-racial-and-gender-groups-in-medical-student-performance-evaluations
#10
David A Ross, Dowin Boatright, Marcella Nunez-Smith, Ayana Jordan, Adam Chekroud, Edward Z Moore
PURPOSE: The transition from medical school to residency is a critical step in the careers of physicians. Because of the standardized application process-wherein schools submit summative Medical Student Performance Evaluations (MSPE's)-it also represents a unique opportunity to assess the possible prevalence of racial and gender disparities, as shown elsewhere in medicine. METHOD: The authors conducted textual analysis of MSPE's from 6,000 US students applying to 16 residency programs at a single institution in 2014-15...
2017: PloS One
https://www.readbyqxmd.com/read/28790228/association-between-serum-uric-acid-and-non-alcoholic-fatty-liver-disease-a-meta-analysis
#11
Guntur Darmawan, Laniyati Hamijoyo, Irsan Hasan
BACKGROUND: non-alcoholic fatty liver disease (NAFLD) is known to be associated with some metabolic disorders. Recent studies suggested the role of uric acid in NAFLD through oxidative stress and inflammatory process. This study is aimed to evaluate the association between serum uric acid and NAFLD. METHODS: a systematic literature review was conducted using Pubmed and Cochrane library. The quality of all studies was assessed using the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE)...
April 2017: Acta Medica Indonesiana
https://www.readbyqxmd.com/read/28782577/down-regulation-of-long-non-coding-rna-meg3-indicates-an-unfavorable-prognosis-in-non-small-cell-lung-cancer-evidence-from-the-geo-database
#12
Zichao Zhang, Tiantian Liu, Kai Wang, Xiao Qu, Zhaofei Pang, Shaorui Liu, Qi Liu, Jiajun Du
Long non-coding RNA (lncRNA) MEG3 (maternally expressed gene 3) is an imprinted gene that suppresses cells growth in various tumors. However, the association between MEG3 expression and prognosis in non-small cell lung cancer (NSCLC) has not been fully investigated. Seven datasets with 1144 patients were obtained from Gene Expression Omnibus (GEO) database (Affymetrix U133 Plus 2.0 platform). Association between MEG3 and other variables was tested using the chi-squared test. Kaplan-Meier survival analysis was carried out to explore the association between MEG3 expression and overall survival (OS)/progression free survival (PFS)...
August 3, 2017: Gene
https://www.readbyqxmd.com/read/28782534/variation-in-adrenal-and-thyroid-hormones-with-life-history-stage-in-juvenile-northern-elephant-seals-mirounga-angustirostris
#13
J A Jelincic, M S Tift, D S Houser, D E Crocker
The classical approach to quantifying the impact of stressors on wildlife is through characterization of hormones associated with the generalized stress response. However, interpretation of hormone data can be difficult due to the range of natural variation within a species and potential confounds of individual and life-history variables. Blood adrenal and thyroid hormones were measured in 144 chemically immobilized yearling northern elephant seals (Mirounga angustirostris) to characterize variation between sexes and across semiannual haul-outs...
August 3, 2017: General and Comparative Endocrinology
https://www.readbyqxmd.com/read/28780991/a-simple-method-for-identification-of-misreporting-of-energy-intake-from-infancy-to-school-age-results-from-a-longitudinal-study
#14
Delphina Gomes, Veronica Luque, Annick Xhonneux, Elvira Verduci, Piotr Socha, Berthold Koletzko, Ursula Berger, Veit Grote
BACKGROUND & AIMS: Misreporting is a major source of reporting bias in nutritional surveys. It can affect the analysis of associations between diet and disease. Although various methods have been proposed to identify misreporting, their application to infants and young children is difficult. We identify misreporting of energy intake in infants and young children and propose a simplified approach. METHODS: 1199 children were enrolled in the Childhood Obesity Programme (CHOP) based in 5 European countries (Belgium, Germany, Italy, Poland and Spain) with repeated measurements of 3-day weighed food protocol and anthropometric indices at 10 time points between ages 1-96 months...
June 1, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28771634/regional-gray-matter-correlates-of-memory-for-emotion-laden-words-in-middle-aged-and-older-adults-a-voxel-based-morphometry-study
#15
Carina Saarela, Juho Joutsa, Matti Laine, Riitta Parkkola, Juha O Rinne, Mira Karrasch
Emotional content is known to enhance memory in a content-dependent manner in healthy populations. In middle-aged and older adults, a reduced preference for negative material, or even an enhanced preference for positive material has been observed. This preference seems to be modulated by the emotional arousal that the material evokes. The neuroanatomical basis for emotional memory processes is, however, not well understood in middle-aged and older healthy people. Previous research on local gray matter correlates of emotional memory in older populations has mainly been conducted with patients suffering from various neurodegenerative diseases...
2017: PloS One
https://www.readbyqxmd.com/read/28771518/cholecystectomy-can-increase-the-risk-of-colorectal-cancer-a-meta-analysis-of-10-cohort-studies
#16
Yong Zhang, Hao Liu, Li Li, Min Ai, Zheng Gong, Yong He, Yunlong Dong, Shuanglan Xu, Jun Wang, Bo Jin, Jianping Liu, Zhaowei Teng
OBJECTIVE: This study aimed to elucidate the effects of cholecystectomy on the risk of colorectal cancer (CRC) by conducting a meta-analysis of 10 cohort studies. METHODS: The eligible cohort studies were selected by searching the PubMed and EMBASE databases from their origination to June 30, 2016, as well as by consulting the reference lists of the selected articles. Two authors individually collected the data from the 10 papers. When the data showed marked heterogeneity, we used a random-effects model to estimate the overall pooled risk; otherwise, a fixed effects model was employed...
2017: PloS One
https://www.readbyqxmd.com/read/28768321/leber-s-hereditary-optic-neuropathy-specific-mutation-m-11778g-a-exists-on-diverse-mitochondrial-haplogroups-in-india
#17
Nahid Akhtar Khan, Periyasamy Govindaraj, Nagasamy Soumittra, Sonika Sharma, Sundaramoorthy Srilekha, Selvakumar Ambika, Ayyasamy Vanniarajan, Angamuthu Kanikannan Meena, Megha S Uppin, Challa Sundaram, Parayil Sankaran Bindu, Narayanappa Gayathri, Arun B Taly, Kumarasamy Thangaraj
Purpose: Leber's hereditary optic neuropathy (LHON; OMIM 535000) is one of the most common maternally inherited mitochondrial disorders. Three mitochondrial DNA point mutations-m.3460G>A (MT-ND1), m.11778G>A (MT-ND4), and m.14484T>C (MT-ND6)-account for the majority of reported LHON cases. Only approximately 50% of males and approximately 10% of females carrying these mutations develop optic neuropathy and blindness. Additional factors, such as mtDNA/nuclear genetic background and environmental modifiers, are likely to contribute toward the observed incomplete penetrance and gender bias...
August 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28768226/you-can-be-too-thin-but-not-too-tall-social-desirability-bias-in-self-reports-of-weight-and-height
#18
Mary A Burke, Katherine G Carman
Previous studies of survey data from the U.S. and other countries find that women tend to understate their body weight on average, while both men and women overstate their height on average. Social norms have been posited as one potential explanation for misreporting of weight and height, but lack of awareness of body weight has been suggested as an alternative explanation, and the evidence presented to date is inconclusive. This paper is the first to offer a theoretical model of self-reporting behavior for weight and height, in which individuals face a tradeoff between reporting an accurate weight (or height) and reporting a socially desirable weight (or height)...
July 13, 2017: Economics and Human Biology
https://www.readbyqxmd.com/read/28767517/accuracy-of-self-reported-weight-in-hispanic-latino-adults-of-the-hispanic-community-health-study-study-of-latinos-hchs-sol
#19
Lindsay Fernández-Rhodes, Whitney R Robinson, Daniela Sotres-Alvarez, Nora Franceschini, Sheila F Castañeda, Christina Buelna, Ashley Moncrieft, Maria Llabre, Martha L Daviglus, Qibin Qi, Anita Agarwal, Carmen R Isasi, Paul Smokowski, Penny Gordon-Larsen, Kari E North
BACKGROUND: Previous United States (U.S.) population-based studies have found that body weight may be underestimated when self-reported. However, this research may not apply to all U.S. Hispanics/Latinos, many of whom are immigrants with distinct cultural orientations to ideal body size. We assessed the data quality and accuracy of self-reported weight in a diverse, community-based, U.S. sample of primarily foreign-born Hispanic/Latino adults. METHODS: Using baseline data (2008-2011) from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL), we described the difference between contemporaneous self-reported and measured current body weight (n=16,119) and used multivariate adjusted models to establish whether the observed trends in misreporting in potential predictors of inaccuracy persisted after adjustment for other predictors...
July 31, 2017: Epidemiology
https://www.readbyqxmd.com/read/28764819/sex-composition-of-twins-and-associations-with-morbidity-mortality-and-maternal-treatment-seeking-outcomes-in-resource-poor-settings
#20
Rob Stephenson, Mondie Blalock Tharp, John Mark Wiginton, Nicholas Metheny
Societal gender inequality and a preference for male children has been shown to be detrimental to girls' health. This is despite females' innate biological advantage early in life. The negative effects of gender inequity on female health are most pronounced in resource-poor countries, where cultural norms supporting a preference for male children are strongest. However, most of what is known about gender inequality and child health comes from studies of singleton births. There is little evidence for how, or if, the disadvantages associated with gender bias and son preference extend to multiple births, a population inherently at risk for a number of health challenges...
August 2, 2017: Journal of Biosocial Science
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