keyword
MENU ▼
Read by QxMD icon Read
search

Infant microbiota

keyword
https://www.readbyqxmd.com/read/28798374/culture-independent-assessment-of-human-milk-microbial-community-in-lactational-mastitis
#1
Shriram H Patel, Yati H Vaidya, Reena J Patel, Ramesh J Pandit, Chaitanya G Joshi, Anju P Kunjadiya
Breastfeeding undoubtedly provides important benefits to the mother-infant dyad and should be encouraged. Mastitis, one of the common but major cause of premature weaning among lactating women, is an inflammation of connective tissue within the mammary gland. This study reports the influence of mastitis on human milk microbiota by utilizing 16 S rRNA gene sequencing approach. We sampled and sequenced microbiome from 50 human milk samples, including 16 subacute mastitis (SAM), 16 acute mastitis (AM) and 18 healthy-controls...
August 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28795339/impact-of-nasopharyngeal-microbiota-on-the-development-of-respiratory-tract-diseases
#2
REVIEW
S Esposito, N Principi
Knowledge of whether and how respiratory microbiota composition can prime the immune system and provide colonisation resistance, limiting consecutive pathobiont overgrowth and infections, is essential to improving the prevention and therapy of respiratory disorders. Modulation of dysbiotic ecosystems or reconstitution of missing microbes might be a possible measure to reduce respiratory diseases. The aim of this review is to analyse the role of nasopharyngeal microbiota in the development of respiratory tract disease in paediatric-age subjects...
August 9, 2017: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/28793975/infant-gut-microbiome-associated-with-cognitive%C3%A2-development
#3
Alexander L Carlson, Kai Xia, M Andrea Azcarate-Peril, Barbara D Goldman, Mihye Ahn, Martin A Styner, Amanda L Thompson, Xiujuan Geng, John H Gilmore, Rebecca C Knickmeyer
BACKGROUND: Studies in rodents provide compelling evidence that microorganisms inhabiting the gut influence neurodevelopment. In particular, experimental manipulations that alter intestinal microbiota impact exploratory and communicative behaviors and cognitive performance. In humans, the first years of life are a dynamic time in gut colonization and brain development, but little is known about the relationship between these two processes. METHODS: We tested whether microbial composition at 1 year of age is associated with cognitive outcomes using the Mullen Scales of Early Learning and with global and regional brain volumes using structural magnetic resonance imaging at 1 and 2 years of age...
June 27, 2017: Biological Psychiatry
https://www.readbyqxmd.com/read/28789705/impact-of-intrapartum-antimicrobial-prophylaxis-upon-the-intestinal-microbiota-and-the-prevalence-of-antibiotic-resistance-genes-in-vaginally-delivered-full-term-neonates
#4
Alicja Nogacka, Nuria Salazar, Marta Suárez, Christian Milani, Silvia Arboleya, Gonzalo Solís, Nuria Fernández, Lidia Alaez, Ana M Hernández-Barranco, Clara G de Los Reyes-Gavilán, Marco Ventura, Miguel Gueimonde
BACKGROUND: Disturbances in the early establishment of the intestinal microbiota may produce important implications for the infant's health and for the risk of disease later on. Different perinatal conditions may be affecting the development of the gut microbiota. Some of them, such as delivery mode or feeding habits, have been extensively assessed whereas others remain to be studied, being critical to identify their impact on the microbiota and, if any, to minimize it. Antibiotics are among the drugs most frequently used in early life, the use of intrapartum antimicrobial prophylaxis (IAP), present in over 30% of deliveries, being the most frequent source of exposure...
August 8, 2017: Microbiome
https://www.readbyqxmd.com/read/28780103/human-milk-oligosaccharide-consumption-by-probiotic-and-human-associated-bifidobacteria-and-lactobacilli
#5
Taksawan Thongaram, Jennifer L Hoeflinger, JoMay Chow, Michael J Miller
Human milk contains high concentrations of nondigestible complex oligosaccharides (human milk oligosaccharides; HMO) that reach the colon and are subsequently fermented by the infant gut microbiota. Using a high-throughput, low-volume growth determination, we evaluated the ability of 12 lactobacilli and 12 bifidobacteria strains, including several commercial probiotics, to ferment HMO and their constituent monomers. Of the 24 strains tested, only Bifidobacterium longum ssp. infantis ATCC 15697 and Bifidobacterium infantis M-63 were able to ferment 3'-sialyllactose, 6'-sialyllactose, 2'-fucosyllactose, and 3'-fucosyllactose...
August 2, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28771949/synbiotic-approaches-to-human-health-and-well-being
#6
Thomas Gurry
Synbiotics refer to combinations of probiotics and prebiotics that act synergistically to confer health benefits to the host. As a therapeutic strategy, they provide a gentle yet powerful method for modulating the composition and metabolic output of the human gut microbiota. In the context of achieving the UN Sustainable Development Goals, synbiotics have the potential to act as cost-effective prophylactic measures against a variety of human ailments, ranging from infant diarrhoea to metabolic and inflammatory diseases in adults, by maintaining commensal microbial communities and metabolic networks that are conducive to human health...
August 3, 2017: Microbial Biotechnology
https://www.readbyqxmd.com/read/28761935/the-skin-microbiome-of-cohabiting-couples
#7
Ashley A Ross, Andrew C Doxey, Josh D Neufeld
Distinct microbial communities inhabit individuals as part of the human skin microbiome and are continually shed to the surrounding environment. Microbial communities from 17 skin sites of 10 sexually active cohabiting couples (20 individuals) were sampled to test whether cohabitation impacts an individual's skin microbiome, leading to shared skin microbiota among partner pairs. Amplified 16S rRNA genes of bacteria and archaea from a total of 340 skin swabs were analyzed by high-throughput sequencing, and the results demonstrated that cohabitation was significantly associated with microbial community composition, although this association was greatly exceeded by characteristics of body location and individuality...
July 2017: MSystems
https://www.readbyqxmd.com/read/28753958/iron-in-micronutrient-powder-promotes-an-unfavorable-gut-microbiota-in-kenyan-infants
#8
Minghua Tang, Daniel N Frank, Audrey E Hendricks, Diana Ir, Fabian Esamai, Edward Liechty, K Michael Hambidge, Nancy F Krebs
Iron supplementation may have adverse health effects in infants, probably through manipulation of the gut microbiome. Previous research in low-resource settings have focused primarily on anemic infants. This was a double blind, randomized, controlled trial of home fortification comparing multiple micronutrient powder (MNP) with and without iron. Six-month-old, non- or mildly anemic, predominantly-breastfed Kenyan infants in a rural malaria-endemic area were randomized to consume: (1) MNP containing 12.5 mg iron (MNP+Fe, n = 13); (2) MNP containing no iron (MNP-Fe, n = 13); or (3) Placebo (CONTROL, n = 7), from 6-9 months of age...
July 19, 2017: Nutrients
https://www.readbyqxmd.com/read/28753043/the-impact-of-storage-conditions-on-the-stability-of-lactobacillus-rhamnosus-gg-and-bifidobacterium-animalis-subsp-lactis-bb12-in-human-milk
#9
Anastasia Mantziari, Juhani Aakko, Himanshu Kumar, Satu Tölkkö, Elloise du Toit, Seppo Salminen, Erika Isolauri, Samuli Rautava
Human milk is the optimal source of complete nutrition for neonates and it also guides the development of infant gut microbiota. Importantly, human milk can be supplemented with probiotics to complement the health benefits of breastfeeding. Storage of human milk for limited periods of time is often unavoidable, but little is known about the effect of different storage conditions (temperature) on the viability of the added probiotics. Therefore, in this study, we evaluated how different storage conditions affect the viability of two specific widely used probiotics, Lactobacillus rhamnosus GG (LGG) and Bifidobacterium animalis subsp...
July 28, 2017: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
https://www.readbyqxmd.com/read/28751453/maternal-modifiers-of-the-infant-gut-microbiota-metabolic-consequences
#10
Christopher M Mulligan, Jacob E Friedman
Transmission of metabolic diseases from mother to child is multifactorial and includes genetic, epigenetic, and environmental influences. Evidence in rodents, humans and non-human primates support the scientific premise that exposure to maternal obesity or high-fat diet during pregnancy creates a long-lasting metabolic signature on the infant innate immune system and the juvenile microbiota which predisposes the offspring to obesity and metabolic diseases. In neonates, gastrointestinal microbes introduced through the mother are noted for their ability to serve as direct inducers/regulators of the infant immune system...
July 27, 2017: Journal of Endocrinology
https://www.readbyqxmd.com/read/28744259/development-of-human-breast-milk-microbiota-associated-mice-as-a-method-to-identify-breast-milk-bacteria-capable-of-colonizing-gut
#11
Xiaoxin Wang, Huifang Lu, Zhou Feng, Jie Cao, Chao Fang, Xianming Xu, Liping Zhao, Jian Shen
Human breast milk is recognized as one of multiple important sources of commensal bacteria for infant gut. Previous studies searched for the bacterial strains shared between breast milk and infant feces by isolating bacteria and performing strain-level bacterial genotyping, but only limited number of milk bacteria were identified to colonize infant gut, including bacteria from Bifidobacterium, Staphylococcus, Lactobacillus, and Escherichia/Shigella. Here, to identify the breast milk bacteria capable of colonizing gut without the interference of bacteria of origins other than the milk or the necessity to analyze infant feces, normal chow-fed germ-free mice were orally inoculated with the breast milk collected from a mother 2 days after vaginal delivery...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28738889/influence-of-the-pneumococcal-conjugate-vaccines-on-the-temporal-variation-of-pneumococcal-carriage-and-the-nasal-microbiota-in-healthy-infants-a-longitudinal-analysis-of-a-case-control-study
#12
Moana Mika, Josua Maurer, Insa Korten, Aurélie Allemann, Suzanne Aebi, Silvio D Brugger, Weihong Qi, Urs Frey, Philipp Latzin, Markus Hilty
BACKGROUND: Bacterial colonization of the upper airways is a prerequisite for subsequent invasive disease. With the introduction of the 7- and 13-valent pneumococcal conjugate vaccines (PCV7 and PCV13), changes in pneumococcal upper airway colonization have been described. It is, however, less evident whether the vaccines lead to compositional changes of the upper airway microbiota. Here, we performed a case-control study using samples from a longitudinal infant cohort from Switzerland...
July 24, 2017: Microbiome
https://www.readbyqxmd.com/read/28727206/the-mother-offspring-dyad-microbial-transmission-immune-interactions-and-allergy-development
#13
REVIEW
Maria C Jenmalm
The increasing prevalence of allergy in affluent countries may be caused by reduced intensity and diversity of microbial stimulation, resulting in abnormal postnatal immune maturation. Most studies investigating the underlying immunomodulatory mechanisms have focused on postnatal microbial exposure, for example demonstrating that the gut microbiota differs in composition and diversity during the first months of life in children who later do or do not develop allergic disease. However, it is also becoming increasingly evident that the maternal microbial environment during pregnancy is important in childhood immune programming, and the first microbial encounters may occur already in utero...
July 20, 2017: Journal of Internal Medicine
https://www.readbyqxmd.com/read/28726512/human-milk-oligosaccharide-categories-define-the-microbiota-composition-in-human-colostrum
#14
J Aakko, H Kumar, S Rautava, A Wise, C Autran, L Bode, E Isolauri, S Salminen
Human milk oligosaccharides (HMOs) are structurally diverse unconjugated glycans with a composition unique to each lactating mother. While HMOs have been shown to have an impact on the development of infant gut microbiota, it is not well known if HMOs also already affect milk microbial composition. To address this question, we analysed eleven colostrum samples for HMO content by high-pressure liquid chromatography and microbiota composition by quantitative PCR. Higher total HMO concentration was associated with higher counts of Bifidobacterium spp...
July 20, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/28721502/mucin-cross-feeding-of-infant-bifidobacteria-and-eubacterium-hallii
#15
Vera Bunesova, Christophe Lacroix, Clarissa Schwab
Mucus production is initiated before birth and provides mucin glycans to the infant gut microbiota. Bifidobacteria are the major bacterial group in the feces of vaginally delivered and breast milk-fed infants. Among the bifidobacteria, only Bifidobacterium bifidum is able to degrade mucin and to release monosaccharides which can be used by other gut microbes colonizing the infant gut. Eubacterium hallii is an early occurring commensal that produces butyrate and propionate from fermentation metabolites but that cannot degrade complex oligo- and polysaccharides...
July 18, 2017: Microbial Ecology
https://www.readbyqxmd.com/read/28713365/what-s-normal-immune-profiling-of-human-milk-from-healthy-women-living-in-different-geographical-and-socioeconomic-settings
#16
Lorena Ruiz, Irene Espinosa-Martos, Cristina García-Carral, Susana Manzano, Michelle K McGuire, Courtney L Meehan, Mark A McGuire, Janet E Williams, James Foster, Daniel W Sellen, Elizabeth W Kamau-Mbuthia, Egidioh W Kamundia, Samwel Mbugua, Sophie E Moore, Linda J Kvist, Gloria E Otoo, Kimberly A Lackey, Katherine Flores, Rossina G Pareja, Lars Bode, Juan M Rodríguez
Human milk provides a very wide range of nutrients and bioactive components, including immune factors, human milk oligosaccharides, and a commensal microbiota. These factors are essential for interconnected processes including immunity programming and the development of a normal infant gastrointestinal microbiome. Newborn immune protection mostly relies on maternal immune factors provided through milk. However, studies dealing with an in-depth profiling of the different immune compounds present in human milk and with the assessment of their natural variation in healthy women from different populations are scarce...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28713343/the-bacterial-ecosystem-of-mother-s-milk-and-infant-s-mouth-and-gut
#17
Elena Biagi, Sara Quercia, Arianna Aceti, Isadora Beghetti, Simone Rampelli, Silvia Turroni, Giacomo Faldella, Marco Candela, Patrizia Brigidi, Luigi Corvaglia
The progressive building of the infants' gut microbiota is pivotal for educating their immune system. Human breast milk is among the first sources of microbes for the assembly of the infant's microbiota, but research struggles to give a demonstration for the origin of bacteria in milk. Aiming at contributing to the knowledge on assembly of the mother's milk and infant's microbiome, here we characterized the oral, gut and milk ecosystems in a homogeneous cohort of 36 healthy mother-infants pairs, by 16S rRNA next-generation sequencing...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28708872/nasopharyngeal-microbiota-in-infants-and-changes-during-viral-upper-respiratory-tract-infection-and-acute-otitis-media
#18
Tasnee Chonmaitree, Kristofer Jennings, Georgiy Golovko, Kamil Khanipov, Maria Pimenova, Janak A Patel, David P McCormick, Michael J Loeffelholz, Yuriy Fofanov
BACKGROUND: Interferences between pathogenic bacteria and specific commensals are known. We determined the interactions between nasopharyngeal microbial pathogens and commensals during viral upper respiratory tract infection (URI) and acute otitis media (AOM) in infants. METHODS: We analyzed 971 specimens collected monthly and during URI and AOM episodes from 139 infants. The 16S rRNA V4 gene regions were sequenced on the Illumina MiSeq platform. RESULTS: Among the high abundant genus-level nasopharyngeal microbiota were Moraxella, Haemophilus, and Streptococcus (3 otopathogen genera), Corynebacterium, Dolosigranulum, Staphylococcus, Acinetobacter, Pseudomonas, and Bifidobacterium...
2017: PloS One
https://www.readbyqxmd.com/read/28708417/association-of-antibiotics-airway-microbiome-and-inflammation-in-infants-with-cystic-fibrosis
#19
Jessica E Pittman, Kristine M Wylie, Kathryn Akers, Gregory A Storch, Joseph Hatch, Jane Quante, Katherine B Frayman, Nadeene Clarke, Miriam Davis, Stephen M Stick, Graham L Hall, Gregory Montgomery, Sarath Ranganathan, Stephanie D Davis, Thomas W Ferkol
RATIONALE: The underlying defect in the cystic fibrosis (CF) airway leads to defective mucociliary clearance and impaired bacterial killing, resulting in endobronchial infection and inflammation that contributes to progressive lung disease. Little is known about the respiratory microbiota in the early CF airway and its relationship to inflammation. OBJECTIVES: To examine the bacterial microbiota and inflammatory profiles in bronchoalveolar lavage fluid and oropharyngeal secretions in infants with CF...
July 14, 2017: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/28706260/early-intervention-with-bifidobacterium-lactis-ncc2818-modulates-the-host-microbe-interface-independent-of-the-sustained-changes-induced-by-the-neonatal-environment
#20
Marie C Lewis, Claire A Merrifield, Bernard Berger, Olivier Cloarec, Swantje Duncker, Annick Mercenier, Jeremy K Nicholson, Elaine Holmes, Mick Bailey
Inflammatory and metabolic diseases can originate during early-life and have been correlated with shifts in intestinal microbial ecology. Here we demonstrate that minor environmental fluctuations during the early neonatal period had sustained effects on the developing porcine microbiota and host-microbe interface. These inter-replicate effects appear to originate during the first day of life, and are likely to reflect very early microbiota acquisition from the environment. We statistically link early systemic inflammation with later local increases in inflammatory cytokine (IL-17) production, which could have important enteric health implications...
July 13, 2017: Scientific Reports
keyword
keyword
74326
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"