Yaqin Jiang, Hucheng Zhu, Chenyang Cui, Chunmei Chen, Nina Wang, Hong Liao, Qin Li, Lina Mao, Nanjin Ding, Jinbing Kang, Jiajun Zhou, Yongji Lai, Zhiping Wang, Yonghui Zhang, Qun Zhou
Two pairs of new bisabolane-type sesquiterpenoids, (+)- aspersydowin A (7S) [(+)-1], (-)- aspersydowin A (7R) [(-)-1], (+)- aspersydowin B (7S,11S) [(+)-2], (-)- aspersydowin B (7R,11R) [(-)-2], along with six known compounds (1-8) were isolated from the fungus Aspergillus sydowii. Compounds 1 and 2 are enantiomers resolved by the Chiralpak IC, using a hexane- propan-2-ol mobile phase. The structure of 1 and 2 with the absolute configuration were assigned tentatively by 1D (1H, 13C, and DEPT) & 2D (HSQC, 1H-1H COSY, HMBC, and NOESY) NMR data analyses and ECD calculations...
August 14, 2023: Chemistry & Biodiversity