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https://www.readbyqxmd.com/read/28802366/formula-for-the-prediction-of-apnea-hypopnea-index-in-children-with-obstructive-sleep-apnea-without-polysomnography-according-to-the-clinical-parameters-is-it-reliable
#1
Zlatko Kljajić, Željka Roje, Kristijan Bečić, Vesna Čapkun, K Vilović, Petar Ivanišević, Eugenija Marušić
PURPOSE OF THE STUDY: The aim of the study was to propose "the risk formula" for obstructive sleep apnea in children according to the general and local clinical parameters and findings relevant for obstructive sleep apnea (OSA) severity. The unmet need for this formula arises from the economic burden of polysomnography (device, staff, training, special sleep centers, etc) as the golden standard for the diagnostics. MATERIALS AND METHODS USED: The study was performed from January 2013 until January 2016 in the Sleep Center, Department for Neuroscience, School of Medicine of the University of Split, Department of Pediatrics, University Hospital Split, Croatia and ENT Dept...
September 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28766829/the-nice-10-minute-physical-restraint-rule-a-discussion-of-the-relative-risks
#2
Lee Hollins
Physical restraint involves "any direct physical contact where the intervener's intention is to prevent, restrict, or subdue movement of the body, or part of the body of another person" (Dept. of Health, 2014 p.26). Such restrictive interventions are used to take control of situations deemed to be dangerous, where there is a real possibility of harm being caused, if no action were to be taken. The actions are designed to end, or significantly reduce, the danger presented to the patient or others including staff (Dept...
August 2, 2017: Journal of Psychiatric and Mental Health Nursing
https://www.readbyqxmd.com/read/28726494/roccellatol-a-new-%C3%AE-orcinol-based-metabolite-from-the-lichen-roccella-montagnei
#3
Uppuluri V Mallavadhani, Akella V S Sudhakar
Roccellatol, a new (2'R,3'S)-erythrityl-2,6-dihydroxy-4-methylbenzoate was isolated along with nine known compounds from the fruticose lichen, Roccella montagnei Bel. em. D.D. Awasthi. The structure of the new compound was elucidated by detailed spectroscopic analysis ((1)H, (13)C, DEPT and HRMS). The present isolation of roccellatol (10) assumes significance as the esters of p-orcellinic acid are rare in lichens. Interestingly, among the known compounds, (+)-montagnetol (9) was now isolated in very large quantity (4...
July 20, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28718238/bacteriology-of-diabetic-foot-in-tertiary-care-hospital-frequency-antibiotic-susceptibility-and-risk-factors
#4
Syeda Sadia Amjad, Jamal Zafar, Nadia Shams
BACKGROUND: Diabetic foot being one of the frequent and disabling complications of diabetes. In view of widespread regional variation in causative organisms and antimicrobial susceptibility, the current study aimed to determine frequency of causative organisms, their antimicrobial susceptibility and associated risk factors. METHODS: This descriptive cross-sectional study was conducted in 6 months' duration at dept. of Medicine; PIMS Hospital Islamabad. Type 2 Diabetes mellitus patients with diabetic foot ulcer were enrolled after informed consent...
April 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28698448/-a-case-of-chronic-myelogenous-leukemia-that-developed-fibrous-pericarditis-owing-to-nilotinib-use
#5
Shogo Miura, Kazuyuki Murase, Akira Sakurada, Kohichi Takada, Satoshi Iyama, Tsutomu Sato, Yasushi Sato, Koji Miyanishi, Masayoshi Kobune, Atsuko Muranaka, Kazutoshi Tachibana, Junji Kato
A 64-year-old man was diagnosed with chronic-phase chronic myelogenous leukemia(CML)in May 2009. He was treated with imatinib and achieved complete cytogenetic response(CCyR)in 2 months. After 4 months of treatment, he developed interstitial pneumonia and became intolerant to imatinib. He was then switched to nilotinib from October of the same year. In June 2013, he was diagnosed with drug-induced pericarditis resulting from nilotinib use, and thus, nilotinib was discontinued. Subsequently, he was followed up without specific treatment for CML...
June 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28677240/application-of-automated-image-analysis-reduces-the-workload-of-manual-screening-of-sentinel-lymph-node-biopsies-in-breast-cancer
#6
Henrik Holten-Rossing, Maj-Lis Møller Talman, Anne Marie Bak Jylling, Anne-Vibeke Laenkholm, Martin Kristensson, Ben Vainer
INTRODUCTION: Breast cancer is one of the most common cancer diseases in women with more than 1.67 million cases diagnosed worldwide each year. In breast cancer, the sentinel lymph node (SLN) pinpoints the first lymph node(s) into which the tumor spreads and it is usually located in the ipsilateral axilla. In patients with no clinical signs of metastatic disease in the axilla, a SLN biopsy (SLNB) is performed. Assessment of metastases in the SLNB is done in a conventional microscope by manually observing a metastasis and measuring its size and/or counting the number of tumor cells...
July 5, 2017: Histopathology
https://www.readbyqxmd.com/read/28671092/clinical-features-of-capillary-bronchitis-related-to-bordetella-pertussis
#7
Yongsheng Xu, Jing Ning, Zhulai Zhang
Pertussis infection can mimick the clinical manifestations of lower airway infection, while the symptoms and signs in some cases are like Bronchiolitis. The paper carried out retrospective analysis of infant pertussis bordetella infected cases admitted by the Respiratory Dept. of Tianjin Children's Hospital for "capillary bronchitis" from Sept. 2015 to Feb. 2016. It analyzed its clinical features, radiological features, laboratory characteristics and outcome through comparing the capillary bronchitis cases induced by the non-bordetella pertussis...
May 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28645717/surveillance-of-pneumococcal-colonization-and-invasive-pneumococcal-disease-reveals-shift-in-prevalent-carriage-serotypes-in-massachusetts-children-to-relatively-low-invasiveness
#8
I Yildirim, B A Little, J Finkelstein, G Lee, W P Hanage, K Shea, S I Pelton
BACKGROUND: Following the introduction of pneumococcal conjugate vaccines (PCV), overall nasopharyngeal colonization rates have not changed significantly, however a dramatic and sustained decline in invasive pneumococcal disease (IPD) in children was observed in every setting where the PCVs were implemented. We aimed to describe the differences in invasive disease potential of serotypes that are common colonizers in pre- and post-vaccine eras in order to provide further insight in our understanding of dynamic epidemiology of pneumococcal diseases...
July 13, 2017: Vaccine
https://www.readbyqxmd.com/read/28633755/dermatologists-mohs-surgeon
#9
Uc Davis School Of Medicine Dept Of Dermatology
The University of California, Davis, School of Medicine, Department of Dermatology, is recruiting for four academic dermatologists in the Clinical X series or Health Sciences Clinical Professor (HSCP) series at the Assistant/Associate/Professor level based on experience and qualifications. Three of these positions are for general medical dermatologists, and one is for a fellowship-trained Mohs surgeon/procedural dermatologist. The appointments may be made up to 100%.
June 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/28599241/triterpene-saponins-from-billia-rosea
#10
Luis De Freitas, Doris Jimenez, Sherley Pimentel, Anne-Claire Mitaine-Offer, Laurent Pouységu, Stéphane Quideau, Thomas Paululat, Freddy Gonzalez-Mujica, Luis B Rojas, María Rodríguez, Marie-Aleth Lacaille-Dubois
Five previously undescribed triterpene saponins, billiosides A-E, and a known analogue, were isolated from the seeds of Billia rosea (Planch. & Linden) C. Ulloa & P. Jørg. Their structures were elucidated on the basis of extensive 1D and 2D NMR experiments ((1)H, (13)C, DEPT, COSY, TOCSY, NOESY, ROESY, HSQC, and HMBC) and mass spectrometry as (3β,21β,22α)-3-[(2-O-β-D-glucopyranosyl-O-[α-L-arabinopyranosyl-(1 → 4)]-β-D-glucopyranosyl)oxy]-21-[((2E,6S)-2,6-dimethyl-6-hydroxyocta-2,7-dienoyl)oxy]-22-(acetyloxy)-24-hydroxyolean-12-en-28-oic acid, (3β,21β,22α)-3-[(2-O-β-D-galactopyranosyl-β-D-glucopyranosyl)oxy]-21,22-dihydroxyolean-12-en-28-yl O-α-L-arabinopyranosyl-(1 → 4)-β-D-glucopyranoside, (3β,21β,22α)-3-[(2-O-β-D-galactopyranosyl-O-[α-L-arabinopyranosyl-(1 → 4)]-β-D-xylopyranosyl)oxy]-21,22-dihydroxyolean-12-en-28-yl O-β-D-glucopyranoside, (3β,21β,22α)-3-[(2-O-β-D-galactopyranosyl-O-[α-L-arabinopyranosyl-(1 → 4)]-β-D-glucopyranosyl)oxy]-21,22-dihydroxyolean-12-en-28-yl O-β-D-glucopyranoside, (3β,21β,22α)-3-[(2-O-β-D-galactopyranosyl-O-[α-L-arabinopyranosyl-(1 → 4)]-β-D-glucopyranosyl)oxy]-21,22-dihydroxyolean-12-en-28-yl O-β-D-glucopyranosyl-(1 → 6)-β-D-glucopyranoside, and dipteroside A...
September 2017: Phytochemistry
https://www.readbyqxmd.com/read/28578966/new-findings-on-green-sweet-pepper-capsicum-annum-pectins-rhamnogalacturonan-and-type-i-and-ii-arabinogalactans
#11
Georgia Erdmann do Nascimento, Marcello Iacomini, Lucimara M C Cordeiro
Polysaccharides were extracted from sweet pepper (Capsicum annum) with hot water and named ANW (9% yield). Starch was precipitated by freeze-thaw treatment, while pectic polysaccharides (8% yield) remained soluble and consisted of GalA (67.0%), Rha (1.6%), Ara (6.4%), Xyl (0.3%), Gal (6.7%) and Glc (4.4%). A highly methoxylated homogalacturonan (HG, degree of methylesterification of 85% and degree of acetylation of 5%), and type I and type II arabinogalactans (AG-I and AG-II) were observed in NMR analyses. These were fractionated with Fehling's solution to give HG (5...
September 1, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28560191/application-of-fuzzy-logic-in-oral-cancer-risk-assessment
#12
Ioana Scrobotă, Grigore Băciuț, Adriana Gabriela Filip, Bianca Todor, Florin Blaga, Mihaela Felicia Băciuț
BACKGROUND: The mapping of the malignization mechanism is still incomplete, but oxidative stress is strongly correlated to carcinogenesis. In our research, using fuzzy logic, we aimed to estimate the oxidative stress related-cancerization risk of the oral potentially malignant disorders. METHODS: Serum from 16 patients diagnosed (clinical and histopathological) with oral potentially malignant disorders (Dept. of Cranio-Maxillofacial Surgery and Radiology, "Iuliu Hațieganu" University of Medicine and Pharmacy, Cluj Napoca, Romania) was processed fluorometric for malondialdehyde and proton donors assays (Dept...
May 2017: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/28552270/the-accuracy-of-bedside-usg-in-the-diagnosis-of-nasal-fractures
#13
Bahadır Caglar, Suha Serin, Serhat Akay, Gokhan Yilmaz, Alper Torun, Zehra Hilal Adıbelli, Ismet Parlak
A comparison of the sensitivity and specificity of bedside ultrasonography with conventional radiography for the evaluation of nasal fractures. INTRODUCTION - PURPOSE: There is increasing use of ultrasonography in the Emergency Dept (ED) and other areas. The purpose of the present study was to evaluate the sensitivity and specificity of bedside ultrasonography with conventional radiographs in the evaluation of nasal fractures in the ED. METHOD: Patients admitted to ED with maxillofacial trauma were evaluated in this prospective study...
May 18, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28537412/-solid-pseudopapillary-neoplasms-of-the-pancreas
#14
J Tesaříková, M Loveček, Č Neoral, K Vomáčková, L Bébarová, P Skalický
INTRODUCTION: Solid pseudopapillary neoplasm (SPN) is a very rare neoplasm that occurs in girls and young women in 90% of cases; the range is 779 years of age, and the median is 28 years of age. This tumour was first described by Virginia Frantz in 1959 as a papillary cystic tumour of the pancreas. METHODS: The aim of this retrospective study was to analyse the incidence of SPN in all patients with a pancreatic tumour operated at the 1st Dept. of Surgery, University Hospital Olomouc between years 2006 and 2015...
2017: Rozhledy V Chirurgii: Měsíčník Československé Chirurgické Společnosti
https://www.readbyqxmd.com/read/28502905/inhibition-of-proinflammatory-mediators-by-coumaroyl-lupendioic-acid-a-new-lupane-type-triterpene-from-careya-arborea-on-inflammation-induced-animal-model
#15
Rayhana Begum, Manjur Ali Sheliya, Showkat R Mir, Ekta Singh, Manju Sharma
ETHNOPHARMACOLOGICAL RELEVANCE: Careya arborea Roxb. (Lecythidaceae) is a large tree found throughout India in deciduous forests and grasslands. C. arborea is traditionally used in tumors, inflammation, anthelmintic, bronchitis, epileptic fits, astringents, antidote to snake-venom, skin disease, diarrhea, dysentery with bloody stools, dyspepsia, ulcer, tooth ache, and ear pain. AIM OF THE STUDY: In our previous work, the methanolic extract of Careya arborea stem bark showed significant anti-inflammatory activity...
July 12, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28491940/data-on-eleven-sesquiterpenoids-from-the-cultured-mycelia-of-ganoderma-capense
#16
Zhen Tan, Jinlian Zhao, Jimei Liu, Min Zhang, Ridao Chen, Kebo Xie, Jungui Dai
The data included in this paper are associated with the research article entitled "Sesquiterpenoids from the cultured mycelia of Ganoderma capense" [1]. (1)H NMR, (13)C NMR, DEPT, HSQC, (1)H-(1)H COSY, HMBC, NOESY, HRESIMS, and IR spectra of Ganodermanol A-H (1-11), together with Mo2(AcO)4-induced CD spectrum of Ganodermanol A, CD spectra of Ganodermanol D-E were included in the Data in Brief article. In addition, the cytotoxicities and anti-HIV-1 activity of isolated compounds were also included in the Data in Brief article...
June 2017: Data in Brief
https://www.readbyqxmd.com/read/28489013/-incidence-cause-and-treatment-of-colonic-perforations-in-iceland-1998-2007-a-nationwide-study
#17
MULTICENTER STUDY
Kristin Jonsdottir, Elsa B Valsdottir, Shreekrishna Datye, Fritz Berndsen, Pall Helgi Moller
INTRODUCTION: Colon perforation is a serious illness with mortality reported from 0-39%. Surgery used to be the gold standard but treatment has changed as studies have indicated comparable results with less invasive treatment. The aim of this study was to evaluate the incidence of acute colon perforations in Iceland, causes and treatment. MATERIAL AND METHODS: A retrospective, nationwide, multicenter analysis was performed based on ICD-10 codes from databases of the main hospitals in Iceland...
February 2017: Læknablađiđ
https://www.readbyqxmd.com/read/28479735/cucurbitane-type-triterpenoids-from-the-blood-glucose-lowering-extracts-of-coccinia-indica-and-momordica-balsamina-fruits
#18
Ujjwal Kaushik, Vidhu Aeri, R Mir Showkat, Mohammad Ali
CONTEXT: Few vegetables that are commonly consumed in India as part of diet have been claimed for their antidiabetic potential. OBJECTIVE: The present study was aimed at evaluating preventive effects of cucurbit vegetables namely, Coccinia indica and Momordica balsamina belonging to family Cucurbitaceae in diabetic hyperglycemia. MATERIALS AND METHODS: The fruits of M. balsamina and C. indica were extracted with chloroform and fractionated with hexane to prepare an extract rich in moderately polar components...
January 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/28465526/%C3%AF-development-%C3%AF-%C3%AF-of%C3%AF-%C3%AF-%C3%AF-a-facescan-3d-facial-reconstruction-technology-method%C3%A2-for-quantitative-evaluation%C3%A2-of-cheilitis-granulomatosa
#19
Chang-Qing Mu, Shi-Qin Wang, Yang Liu, Chun-Lei Li, Xiao-Sheng Hu, Hong Hua
We explored the applicability of Facescan three-dimensional (3D) facial reconstruction technology for adjunctive diagnosis and therapeutic evaluation of cheilitis granulomatosa (CG) in 33 patients with CG and 29 healthy controls at the Dept. of Oral Medicine, Peking University, School and Hospital of Stomatology (PKUSS), from January 2015 to May 2016. The Facescan structured-light 3D facial reconstruction scanner was used to scan the scope of lips in both groups, in order to acquire 3D morphological data of the lips...
May 2, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28448888/isolation-identification-and-characterization-of-potential-impurities-of-anidulafungin
#20
Lanning Zhao, Qilong Wang, Yi Bie, Xiaoxia Lu
Eight impurities ranging from 0.03 to 0.97% in anidulafungin bulk drug were detected by HPLC. Four impurities (Imp-I, Imp-II, Imp-III and Imp-VIII) among impurities were isolated from the self-prepared or marketed samples of anidulafungin bulk drug by means of preparative HPLC. A thorough study was undertaken to characterize these impurities and based on 1D ((1)H, (13)C, H-D, DEPT 90 and 135) and 2D (COSY, TOCSY, HSQC, HMBC) NMR and ESI-MS spectral data. Based on the characterization data, Imp-I was found to be known open-chain hydrolysis product formed during the synthesis and degradation...
April 17, 2017: Journal of Pharmaceutical and Biomedical Analysis
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