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Keywords Atrial fibrillation and heart ...

Atrial fibrillation and heart failure

https://read.qxmd.com/read/38535093/cardiopulmonary-exercise-testing-in-heart-failure
#1
REVIEW
Michel Juarez, Cristian Castillo-Rodriguez, Dina Soliman, Gaspar Del Rio-Pertuz, Kenneth Nugent
Cardiopulmonary exercise testing (CPET) provides important information for the assessment and management of patients with heart failure. This testing measures the respiratory and cardiac responses to exercise and allows measurement of the oxygen uptake (V˙O2 ) max and the relationship between minute ventilation (V˙E) and carbon dioxide excretion (V˙CO2 ). These two parameters help classify patients into categories that help predict prognosis, and patients with a V˙O2 < 14 mL/kg/min and V˙E/V˙CO2 slope >35 have a poor prognosis...
February 20, 2024: Journal of Cardiovascular Development and Disease
https://read.qxmd.com/read/38535079/skin-lesions-with-loss-of-tissue-and-cutaneous-onset-sepsis-the-skin-infection-sepsis-relationship
#2
JOURNAL ARTICLE
Adriana-Ionela Pătrașcu, Dan Vâță, Doinița Temelie-Olinici, Mădălina Mocanu, Dumitrița-Lenuța Guguluș, Mădălina Marinescu, Liviu Stafie, Bogdan-Marian Tarcău, Ioana Creţu, Ioana-Adriana Popescu, Carmen-Diana Cimpoeșu, Laura Gheucă-Solovăstru
Infectious and inflammatory dermatoses featuring skin lesions with loss of tissue expose skin layers to microbial invasions, disrupt the normal skin microbiome, and potentially lead to sepsis. However, literature data on the incidence of cutaneous-onset sepsis are scarce. This retrospective observational study assessed hospital admissions for primary skin lesions without bacterial infections and sepsis during 2020-2022 in the largest emergency hospital in NE Romania. Of 509 patients, 441 had infected lesions, 78 had sepsis caused by venous ulcers from microbial eczema cellulitis, superinfected bullous dermatoses, erysipelas, and erythroderma...
March 21, 2024: Diagnostics
https://read.qxmd.com/read/38533983/risk-of-death-and-cardiovascular-events-in-asian-patients-with-atrial-fibrillation-and-chronic-obstructive-pulmonary-disease-a-report-from-the-prospective-aphrs-registry
#3
JOURNAL ARTICLE
Tommaso Bucci, Giulio Francesco Romiti, Alena Shantsila, Wee-Siong Teo, Hyung-Wook Park, Wataru Shimizu, Bernadette Corica, Marco Proietti, Hung-Fat Tse, Tze-Fan Chao, Frederick Frost, Gregory Y H Lip
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is associated with an increased risk of adverse events in patients with atrial fibrillation (AF); however, few data are available on this topic in Asian populations. METHODS AND RESULTS: Prospective observational study conducted on patients with AF enrolled in the Asia-Pacific Heart Rhythm Society (APHRS) AF Registry. The diagnosis of COPD was based on data reported in the case report form by the investigators...
March 27, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38533962/lower-recurrence-rates-of-atrial-fibrillation-and-mace-events-after-early-compared-to-late-ablation-a-danish-nationwide-register-study
#4
JOURNAL ARTICLE
Jacob Tønnesen, Martin H Ruwald, Jannik Pallisgaard, Peter Vibe Rasmussen, Arne Johannessen, Jim Hansen, Rene H Worck, Christopher R Zörner, Lise Riis-Vestergaard, Charlotte Middelfart, Samuel K Sørensen, Stefan Sattler, Gunnar Gislason, Morten Lock Hansen
BACKGROUND: Guidelines recommend prioritizing treatment with antiarrhythmic drugs before referral of patients with atrial fibrillation to ablation, delaying a potential subsequent ablation. However, delaying ablation may affect ablation outcomes. We sought to investigate the impact of duration from diagnosis to ablation on the risk of atrial fibrillation recurrence and adverse events. METHODS AND RESULTS: Using Danish nationwide registries, all patients with first-time ablation for atrial fibrillation were identified and included from 2010 to 2018...
March 27, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38533961/correlates-of-plasma-nt-probnp-cyclic-gmp-ratio-in-heart-failure-with-preserved-ejection-fraction-an-analysis-of-the-relax-trial
#5
JOURNAL ARTICLE
Leonard Chiu, Vineet Agrawal, David Armstrong, Evan Brittain, Sheila Collins, Anna R Hemnes, Joseph A Hill, JoAnn Lindenfeld, Sanjiv J Shah, Lynne W Stevenson, Thomas J Wang, Deepak K Gupta
BACKGROUND: Phosphodiesterases degrade cyclic GMP (cGMP), the second messenger that mediates the cardioprotective effects of natriuretic peptides. High natriuretic peptide/cGMP ratio may reflect, in part, phosphodiesterase activity. Correlates of natriuretic peptide/cGMP in patients with heart failure with preserved ejection fraction are not well understood. Among patients with heart failure with preserved ejection fraction in the RELAX (Phosphodiesterase-5 Inhibition to Improve Clinical Status and Exercise Capacity in Heart Failure With Preserved Ejection Fraction) trial, we examined (1) cross-sectional correlates of circulating NT-proBNP (N-terminal pro-B-type natriuretic peptide)/cGMP ratio, (2) whether selective phosphodiesterase-5 inhibition by sildenafil changed the ratio, and (3) whether the effect of sildenafil on 24-week outcomes varied by baseline ratio...
March 27, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38532020/contemporary-pharmacological-treatment-and-management-of-heart-failure
#6
REVIEW
Biykem Bozkurt
The prevention and treatment strategies for heart failure (HF) have evolved in the past two decades. The stages of HF have been redefined, with recognition of the pre-HF state, which encompasses asymptomatic patients who have developed either structural or functional cardiac abnormalities or have elevated plasma levels of natriuretic peptides or cardiac troponin. The first-line treatment of patients with HF with reduced ejection fraction includes foundational therapies with angiotensin receptor-neprilysin inhibitors, angiotensin-converting enzyme inhibitors or angiotensin receptor blockers, β-blockers, mineralocorticoid receptor antagonists, sodium-glucose cotransporter 2 (SGLT2) inhibitors and diuretics...
March 26, 2024: Nature Reviews. Cardiology
https://read.qxmd.com/read/38531010/covert-cerebrovascular-changes-in-people-with-heart-disease-a-systematic-review-and-meta-analysis
#7
JOURNAL ARTICLE
Zien Zhou, Shoujiang You, Yuki Sakamoto, Ying Xu, Song Ding, Wenyi Xu, Wenjie Li, Jie Yu, Yanan Wang, Katie Harris, Candice Delcourt, Mathew J Reeves, Richard I Lindley, Mark W Parsons, Mark Woodward, Craig Anderson, Xin Du, Jun Pu, Joanna M Wardlaw, Cheryl Carcel
BACKGROUND AND OBJECTIVES: To determine the prevalence of silent brain infarction (SBI) and cerebral small vessel disease (CSVD) in adults with atrial fibrillation (AF), coronary artery disease, heart failure or cardiomyopathy, heart valve disease, and patent foramen ovale (PFO), with comparisons between those with and without recent stroke and an exploration of associations between heart disease and SBI/CSVD. METHODS: Medline, Embase, and Cochrane Library were systematically searched for hospital-based or community-based studies reporting SBI/CSVD in people with heart disease...
April 23, 2024: Neurology
https://read.qxmd.com/read/38530599/how-well-do-ed-physician-practices-align-with-the-caep-acute-atrial-fibrillation-checklist-for-stroke-prevention-and-disposition
#8
JOURNAL ARTICLE
Samara Adler, Amanda M S Mattice, Debra Eagles, Krishan Yadav, Sean Hui, Althaf Azward, Nikesh Pandey, Ian Stiell
OBJECTIVES: Acute atrial fibrillation (AF)/flutter (AFL) is a common emergency department (ED) presentation. In 2021, an updated version of CAEP's Acute AF/AFL Best Practices Checklist was published, seeking to guide management. We assessed the alignment with and safety of application of the Checklist, regarding stroke prevention and disposition. METHODS: This health records review included adults presenting to two tertiary care academic EDs between January and August 2022 with a diagnosis of acute AF/AFL...
March 26, 2024: CJEM
https://read.qxmd.com/read/38529655/repeated-measurement-of-the-novel-atrial-biomarker-bmp10-bone-morphogenetic-protein-10-refines-risk-stratification-in-anticoagulated-patients-with-atrial-fibrillation-insights-from-the-aristotle-trial
#9
JOURNAL ARTICLE
Konstantinos I Gkarmiris, Johan Lindbäck, John H Alexander, Christopher B Granger, Peter Kastner, Renato D Lopes, André Ziegler, Jonas Oldgren, Agneta Siegbahn, Lars Wallentin, Ziad Hijazi
BACKGROUND: BMP10 (bone morphogenic protein 10) has emerged as a novel biomarker associated with the risk of ischemic stroke and other outcomes in patients with atrial fibrillation (AF). The study aimed to determine if repeated BMP10 measurements improve prognostication of cardiovascular events in patients with AF. METHODS AND RESULTS: BMP10 was measured using a prototype Elecsys immunoassay in plasma samples collected at randomization and after 2 months in patients with AF randomized to apixaban or warfarin in the ARISTOTLE (Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation) trial (n=2878)...
March 26, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38525097/contemporary-spectrum-characteristics-and-outcomes-of-adult-patients-with-rheumatic-valvular-disease-in-china-insights-from-the-china-vhd-study
#10
JOURNAL ARTICLE
Zhenya Duan, Yunqing Ye, Zhe Li, Bin Zhang, Qingrong Liu, Zhenyan Zhao, Weiwei Wang, Zikai Yu, Haitong Zhang, Qinghao Zhao, Bincheng Wang, Junxing Lv, Shuai Guo, Haocheng Ren, Runlin Gao, Haiyan Xu, Yongjian Wu
BACKGROUND: Rheumatic valvular disease (RVD) represents a significant health concern in developing countries, yet a scarcity of detailed data exists. This study conducts a comprehensive examination of RVD patients in China, exploring aspects of the disease's spectrum, characteristics, investigation, management, and outcomes. METHODS: The China Valvular Heart Disease (China-VHD) study, a nationwide, multicenter, prospective observational study, enrolled 13,917 adults with moderate-to-severe valvular heart disease from April to June 2018...
June 2024: Int J Cardiol Cardiovasc Risk Prev
https://read.qxmd.com/read/38524992/a-tale-of-three-chambers-cor-triatriatum-sinistrum
#11
Maliha Butt, Husban Halim, Ataul Qureshi, Ryan Koene, Su Aung, Tara Karamlou, Ashish Saini
• Cor triatriatum is an important cause of HF and atrial arrhythmias in young adults. • Misdiagnosis can cause inappropriate interventions and delay in surgical treatment. • Integrated imaging is useful in describing anatomy and associated abnormalities. • Collaboration between hospitals and cardiac specialties helps prevent poor outcomes.
March 2024: CASE: Cardiovascular Imaging Case Reports
https://read.qxmd.com/read/38524021/intraoperative-acute-cardiac-tamponade-as-a-result-of-intracardiac-perforation-requiring-emergency-continuous-pericardiocentesis-and-open-sternotomy-a-case-report-and-literature-review-of-a-rare-but-fatal-complication
#12
Christopher M Russo, Mitchell E Harrison, Nathaniel M Harry, John R Benjamin, Christian Popa
Intraoperative acute cardiac tamponade associated with iatrogenic intracardiac perforation from percutaneous interventional cardiac procedures is a rare but potentially catastrophic complication. We report a case of intraoperative acute hemopericardium caused by a left atrial (LA) perforation resulting in cardiac tamponade in a patient undergoing a baffling procedure for the correction of two anomalous pulmonary veins draining into her superior vena cava (SVC) that required continuous pericardiocentesis with autologous blood transfusion via the femoral vein and an emergency intraoperative transfer from the interventional cardiology cath lab to the cardiac operating room for an open sternotomy and primary repair...
February 2024: Curēus
https://read.qxmd.com/read/38522770/prevalence-and-impact-of-pulmonary-hypertension-on-acute-decompensated-heart-failure-with-preserved-ejection-fraction-hospitalizations-a-five-year-retrospective-analysis
#13
REVIEW
Omar Al Wahadneh, Qusai Alitter, Apoorva Raju, Nmair Alziadin, Abdullah H Alshurafa, Hamdi Osama Aldabbas, Ibrahim Shaik
Heart Failure with Preserved Ejection Fraction (HFpEF) is a major and common cardiovascular condition with widely variable clinical outcomes. Pulmonary hypertension (PH) often co-exists with HFpEF and tends to affect patient outcomes; this study aims to identify the impact of PH on the clinical outcome of patients admitted to the hospital with acute HFpEF exacerbations. We analyzed data from the National Inpatient Sample between 2016 and 2020, focusing on 464,438 acute HFpEF exacerbation hospitalizations. Outcomes were compared between those with PH (27...
March 22, 2024: Current Problems in Cardiology
https://read.qxmd.com/read/38522599/risk-of-clinically-significant-cardiovascular-disease-associated-with-postoperative-radiotherapy-in-non-small-cell-lung-cancer-patients-receiving-surgical-resection-followed-by-adjuvant-chemotherapy-a-korean-nationwide-cohort-study
#14
JOURNAL ARTICLE
Jeanny Kwon, Byoung Hyuck Kim
BACKGROUND: There are no large-scale datasets that analyze the relationship between postoperative radiotherapy (PORT) and various cardiovascular diseases (CVDs) in patients with locally advanced non-small cell lung cancer (NSCLC). Therefore, we aimed to investigate the incidences of CVDs with PORT using a national population-based database. METHODS: Patients diagnosed with NSCLC who underwent curative surgery followed by adjuvant chemotherapy were included from 2007 to 2017...
March 22, 2024: Radiotherapy and Oncology
https://read.qxmd.com/read/38521897/predictors-of-improvement-in-left-ventricular-systolic-function-after-catheter-ablation-in-patients-with-persistent-atrial-fibrillation-complicated-with-heart-failure
#15
JOURNAL ARTICLE
Xinliang Zhao, Xiaoqin Hu, Wei Bao, Shuo Huang, Fei Li, Chen Liu, Liqi Ge, Quan Zhang, Chaoqun Zhang, Chengzong Li
AIMS: The current management of patients with atrial fibrillation (AF) and concomitant heart failure (HF) remains a significant challenge. Catheter ablation (CA) has been shown to improve left ventricular ejection fraction (LVEF) in these patients, but which patients can benefit from CA is still poorly understood. The aim of our study was to determine the predictors of improved ejection fraction in patients with persistent atrial fibrillation (PeAF) complicated with HF undergoing CA. METHODS AND RESULTS: A total of 435 patients with persistent AF underwent an initial CA between January 2019 and March 2023 in our hospital...
March 23, 2024: BMC Cardiovascular Disorders
https://read.qxmd.com/read/38521289/predictors-of-mortality-and-burden-of-arrhythmias-in-endstage-heart-failure
#16
REVIEW
Endurance Evbayekha, Akanimo Antia, Brittany Dixon, Craig K Reiss, Shane Larue
BACKGROUND: Heart failure (HF) is a significant cause of morbidity and mortality in the United States, contributing to approximately 1 in 8 deaths. Individuals with end-stage HF (eHF) experience debilitating symptoms leading to poor quality of life (QoL). METHODS: We used the ICD-10 code for eHF (I5084) from the National Inpatient Sample (NIS) (2016-2020) to identify all patients with eHF. We used a multivariable logistic regression model to adjust for confounders and estimate the mortality probability in each arrhythmia cohort...
March 21, 2024: Current Problems in Cardiology
https://read.qxmd.com/read/38520461/utility-and-validity-of-the-hfa-peff-and%C3%A2-h-2-fpef-scores-in-patients-with-symptomatic-atrial-fibrillation
#17
JOURNAL ARTICLE
Jonathan P Ariyaratnam, Ricardo S Mishima, Kadhim Kadhim, Mehrdad Emami, John L Fitzgerald, Anand Thiyagarajah, Jenelle K Dziano, Jackson O Howie, Melissa E Middeldorp, Prashanthan Sanders, Adrian D Elliott
BACKGROUND: Diagnosis of heart failure with preserved ejection fraction (HFpEF) in patients with atrial fibrillation (AF) represents a significant clinical challenge. Two diagnostic scoring tools have been developed to aid the noninvasive diagnosis of HFpEF: the HFA-PEFF (Heart Failure Association Pre-test assessment, Echocardiography and natriuretic peptide, Functional testing, Final etiology) and the H2 FPEF scoring systems. OBJECTIVES: The purpose of this study was to evaluate the performance of these 2 scoring tools for the diagnosis of HFpEF against a gold standard of invasive evaluation in a cohort of patients with AF...
March 8, 2024: JACC. Heart Failure
https://read.qxmd.com/read/38520149/sodium-glucose-cotransporter-2-inhibitors-and-the-risk-of-atrial-fibrillation-in-patients-with-type-2-diabetes-a-population-based-cohort-study
#18
JOURNAL ARTICLE
Talip E Eroglu, Ruben Coronel, Patrick C Souverein
AIMS: Sodium-glucose cotransporter-2 inhibitors (SGLT-2is) have a direct cardiac effect that is likely to be independent of its glucose lowering renal effect. Previous research has shown that SGLT2-is mitigate heart failure and prevent arrhythmic cardiac death. Our objective is to determine whether SGLT-2is reduce atrial fibrillation (AF) in comparison to other second-to third-line antidiabetic drugs in type 2 diabetes. METHODS AND RESULTS: We conducted a population-based, new-user active comparator cohort study using data from the UK Clinical Practice Research Datalink...
March 22, 2024: European Heart Journal. Cardiovascular Pharmacotherapy
https://read.qxmd.com/read/38519830/assessment-of-physician-compliance-to-the-caep-2021-atrial-fibrillation-best-practices-checklist-for-rate-and-rhythm-control-in-the-emergency-department
#19
JOURNAL ARTICLE
Amanda M S Mattice, Samara Adler, Debra Eagles, Krishan Yadav, Sean Hui, Althaf Azward, Nikesh Pandey, Ian G Stiell
OBJECTIVES: Acute atrial fibrillation and flutter (AF/AFL) are common arrhythmias treated in the emergency department (ED). The 2021 CAEP Best Practices Checklist provides clear recommendations for management of patients with acute AF/AFL. This study aimed to evaluate physician compliance to Checklist recommendations for risk assessment and ED management of AF/AFL. METHODS: This health records review assessed the management of adult patients presenting to two tertiary care EDs for management of acute AF/AFL from January to August, 2022...
March 23, 2024: CJEM
https://read.qxmd.com/read/38519537/prediction-of-pacemaker-induced-cardiomyopathy-using-a-convolutional-neural-network-based-on-clinical-findings-prior-to-pacemaker-implantation
#20
JOURNAL ARTICLE
Mitsunori Oida, Takuya Mizutani, Eriko Hasumi, Katsuhito Fujiu, Kosaku Goto, Kunihiro Kani, Tsukasa Oshima, Takumi J Matsubara, Yu Shimizu, Gaku Oguri, Toshiya Kojima, Issei Komuro
Risk factors for pacemaker-induced cardiomyopathy (PICM) have been previously reported, including a high burden of right ventricular pacing, lower left ventricular ejection fraction, a wide QRS duration, and left bundle branch block before pacemaker implantation (PMI). However, predicting the development of PICM remains challenging. This study aimed to use a convolutional neural network (CNN) model, based on clinical findings before PMI, to predict the development of PICM. Out of a total of 561 patients with dual-chamber PMI, 165 (mean age 71...
March 22, 2024: Scientific Reports
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