keyword
MENU ▼
Read by QxMD icon Read
search

Periampullary cancer

keyword
https://www.readbyqxmd.com/read/27882511/over-700-whipples-for-pancreaticobiliary-malignancies-postoperative-morbidity-is-an-additional-negative-prognostic-factor-for-distal-bile-duct-cancer
#1
Stefano Andrianello, Giovanni Marchegiani, Giuseppe Malleo, Borislav Chavdarov Rusev, Aldo Scarpa, Deborah Bonamini, Laura Maggino, Claudio Bassi, Roberto Salvia
BACKGROUND: Distal cholangiocarcinomas and pancreatic cancers both arise from pancreaticobiliary epithelium. Despite their common origin, there is a possible discrepancy in outcome. We analysed the surgical, pathological and survival outcome of resected distal cholangiocarcinoma compared with pancreatic cancer. METHODS: All cases of resected distal cholangiocarcinoma and pancreatic cancer from 1998 to 2014 were extracted from our database. Outcomes were compared...
November 23, 2016: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/27865285/palliative-care-for-pancreatic-and-periampullary-cancer
#2
REVIEW
Jennifer A Perone, Taylor S Riall, Kelly Olino
Most patients with pancreatic cancer will present with metastatic or locally advanced disease. Unfortunately, most patients with localized disease will experience recurrence even after multimodality therapy. As such, pancreatic cancer patients arrive at a common endpoint where decisions pertaining to palliative care come to the forefront. This article summarizes surgical, endoscopic, and other palliative techniques for relief of obstructive jaundice, relief of duodenal or gastric outlet obstruction, and relief of pain due to invasion of the celiac plexus...
December 2016: Surgical Clinics of North America
https://www.readbyqxmd.com/read/27865278/adjuvant-and-neoadjuvant-therapy-for-resectable-pancreatic-and-periampullary-cancer
#3
REVIEW
Stephanie M Kim, Jennifer R Eads
Pancreatic adenocarcinoma is a relatively uncommon malignancy associated with a high rate of cancer-related mortality despite best efforts to perform curative surgery. Adjuvant therapy in patients after surgical resection is associated with improved overall survival. Adjuvant treatment approaches may include either chemotherapy alone or a combination of chemotherapy and radiation therapy. Neoadjuvant approaches, also including either chemotherapy alone or a combination of chemotherapy and radiation therapy, are under investigation...
December 2016: Surgical Clinics of North America
https://www.readbyqxmd.com/read/27865277/surgical-therapy-for-pancreatic-and-periampullary-cancer
#4
REVIEW
John B Ammori, Kevin Choong, Jeffrey M Hardacre
Surgery is the key component of treatment for pancreatic and periampullary cancers. Pancreatectomy is complex, and there are numerous perioperative and intraoperative factors that are important for achieving optimal outcomes. This article focuses specifically on key aspects of the surgical management of periampullary and pancreatic cancers.
December 2016: Surgical Clinics of North America
https://www.readbyqxmd.com/read/27859270/impact-of-pancreatectomy-on-long-term-patient-reported-symptoms-and-quality-of-life-in-recurrence-free-survivors-of-pancreatic-and-periampullary-neoplasms
#5
Jordan M Cloyd, Hop S Tran Cao, Maria Q B Petzel, Jason W Denbo, Nathan H Parker, Graciela M Nogueras-González, Joseph S Liles, Michael P Kim, Jeffrey E Lee, Jean-Nicolas Vauthey, Thomas A Aloia, Jason B Fleming, Matthew H G Katz
BACKGROUND: Long term patient-reported symptoms and quality of life (QOL) are important outcome metrics following cancer operations, but have been poorly described in patients who have previously undergone pancreatectomy. METHODS: We conducted a cross-sectional survey of recurrence-free survivors of pancreatic ductal adenocarcinoma, periampullary carcinomas, and pancreatic neuroendocrine tumors who had undergone prior pancreatectomy. QOL and symptom burden were measured using the Functional Assessment of Cancer Therapy-Hepatobiliary Questionnaire, and psychosocial distress was measured using the Hospital Anxiety and Depression Scale...
November 11, 2016: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27829047/immunohistochemical-typing-of-adenocarcinomas-of-the-pancreatobiliary-system-improves-diagnosis-and-prognostic-stratification
#6
Carlos Fernández Moro, Alejandro Fernandez-Woodbridge, Melroy Alistair D'souza, Qianni Zhang, Benedek Bozoky, Senthil Vasan Kandaswamy, Piera Catalano, Rainer Heuchel, Sonia Shtembari, Marco Del Chiaro, Olof Danielsson, Mikael Björnstedt, J Matthias Löhr, Bengt Isaksson, Caroline Verbeke, Béla Bozóky
BACKGROUND & AIMS: Adenocarcinomas of the pancreatobiliary system are currently classified by their primary anatomical location. In particular, the pathological diagnosis of intrahepatic cholangiocarcinoma is still considered as a diagnosis of exclusion of metastatic adenocarcinoma. Periampullary cancers have been previously classified according to the histological type of differentiation (pancreatobiliary, intestinal), but overlapping morphological features hinder their differential diagnosis...
2016: PloS One
https://www.readbyqxmd.com/read/27778242/surgical-margins-for-duodenopancreatectomy
#7
R Coppola, M Cartillone, D Borzomati, G Nappo, S Valeri, T Petitti, G Perrone
Microscopic residual tumor (R1) affects prognosis of resected pancreatic head cancer patients. Surgeon's ability, caseload and accuracy of pathological staging affect the rate of R1 resections. The goal of this study was to verify if a standardized histopathological workup of the specimen affects the rate of microscopic residual tumor after PD for cancer. Two groups of specimens were managed with (Group 1, Standardized Group, SG) or without (Group 2, Non Standardized Group, NSG) a standardized histopathological workup reported by the Royal College of Pathologists...
September 2016: Updates in Surgery
https://www.readbyqxmd.com/read/27776651/double-contrast-enhanced-ultrasonography-in-the-detection-of-periampullary-cancer-comparison-with-b-mode-ultrasonography-and-mr-imaging
#8
Ting Zhang, Zhong-Zhen Su, Ping Wang, Tao Wu, Wen Tang, Er-Jiao Xu, Jin-Xiu Ju, Xian-Yue Quan, Rong-Qin Zheng
PURPOSE: To investigate the value of double contrast-enhanced ultrasonography (DCEUS) in the detection of periampullary cancer. MATERIALS AND METHODS: Ninety-nine patients with surgery or biopsy-proven periampullary cancer who underwent both DCEUS and magnetic resonance imaging (MRI) examinations before operation were enrolled in our study. DCEUS in which intravenous microbubbles were used in combination with oral contrast agent and MRI were performed preoperatively to make a detection diagnosis of periampullary cancer...
November 2016: European Journal of Radiology
https://www.readbyqxmd.com/read/27732711/association-of-histopathologic-phenotype-of-periampullary-adenocarcinomas-with-survival
#9
Jennifer L Williams, Carmen K Chan, Paul A Toste, Irmina A Elliott, Charles R Vasquez, Dharma B Sunjaya, Eric A Swanson, Jamie Koo, O Joe Hines, Howard A Reber, David W Dawson, Timothy R Donahue
Importance: Patients with periampullary adenocarcinomas have widely variable survival. These cancers are traditionally categorized by their anatomic location of origin, namely, the duodenum, ampulla, distal common bile duct (CBD), or head of the pancreas. However, they can be alternatively subdivided histopathologically into intestinal or pancreaticobiliary (PB) types, which may more accurately estimate prognosis. Objectives: To identify factors associated with survival in patients with periampullary adenocarcinomas and to compare survival between those having intestinal-type or PB-type cancers originating from the duodenum, ampulla, or distal CBD with those having pancreatic ductal adenocarcinoma (PDAC)...
October 12, 2016: JAMA Surgery
https://www.readbyqxmd.com/read/27732696/biology-trumps-anatomic-location-in-periampullary-cancers
#10
Richard J Bold
No abstract text is available yet for this article.
October 12, 2016: JAMA Surgery
https://www.readbyqxmd.com/read/27730351/surgical-strategy-and-outcome-in-patients-undergoing-pancreaticoduodenectomy-after-gastric-resection-a-three-center-experience-with-39-patients
#11
Dooin Lee, Jae Hoon Lee, Dongho Choi, Chang Moo Kang, Jae Uk Chong, Song-Chul Kim, Kyeong Geun Lee
BACKGROUND: Stomach cancer is the second most commonly diagnosed cancer in Korea. Although the long-term survival outcome has improved, secondary primary tumors from periampullary regions are increasing inevitably and pancreaticoduodenectomy (PD) following gastrectomy is challenging. This study evaluates the surgical outcomes of PD following gastrectomy and suggests the optimum method for reconstruction. METHODS: Patients who underwent curative PD with a history of gastric resection between 2005 and 2015 were assessed retrospectively...
October 11, 2016: World Journal of Surgery
https://www.readbyqxmd.com/read/27644962/factors-predicting-adequate-lymph-node-yield-in-patients-undergoing-pancreatoduodenectomy-for-malignancy
#12
Marek Sierzega, Łukasz Bobrzyński, Andrzej Matyja, Jan Kulig
BACKGROUND: Most pancreatoduodenectomy resections do not meet the minimum of 12 lymph nodes recommended by the American Joint Committee on Cancer for accurate staging of periampullary malignancies. The purpose of this study was to investigate factors affecting the likelihood of adequate nodal yield in pancreatoduodenectomy specimens subject to routine pathological assessment. METHODS: Six hundred sixty-two patients subject to pancreatoduodenectomy between 1990 and 2013 for pancreatic, ampullary, and common bile duct cancers were reviewed...
September 20, 2016: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27638672/skeletal-muscle-quality-is-associated-with-worse-survival-after-pancreatoduodenectomy-for-periampullary-nonpancreatic-cancer
#13
L B Van Rijssen, N C M van Huijgevoort, R J S Coelen, J A Tol, E B Haverkort, C Y Nio, O R Busch, M G Besselink
BACKGROUND: Body composition measures may predict outcomes of cancer surgery. Whereas low muscle mass shown on preoperative computed tomography (CT) scans has been associated with worse outcomes after surgery for pancreatic cancer, less consideration has been given to low muscle attenuation, reflecting poor muscle quality. Studies relating muscle mass and muscle attenuation with outcomes for patients with periampullary, nonpancreatic cancer are lacking. METHODS: Skeletal muscle mass and attenuation were assessed in 166 consecutive patients undergoing pancreatoduodenectomy (PD) for periampullary, nonpancreatic cancer at a single center between 2000 and 2012...
September 8, 2016: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/27631326/diagnostic-accuracy-of-different-imaging-modalities-following-computed-tomography-ct-scanning-for-assessing-the-resectability-with-curative-intent-in-pancreatic-and-periampullary-cancer
#14
Domenico Tamburrino, Deniece Riviere, Mohammad Yaghoobi, Brian R Davidson, Kurinchi Selvan Gurusamy
BACKGROUND: Periampullary cancer includes cancer of the head and neck of the pancreas, cancer of the distal end of the bile duct, cancer of the ampulla of Vater, and cancer of the second part of the duodenum. Surgical resection is the only established potentially curative treatment for pancreatic and periampullary cancer. A considerable proportion of patients undergo unnecessary laparotomy because of underestimation of the extent of the cancer on computed tomography (CT) scanning. Other imaging methods such as magnetic resonance imaging (MRI), positron emission tomography (PET), PET-CT, and endoscopic ultrasound (EUS) have been used to detect local invasion or distant metastases not visualised on CT scanning which could prevent unnecessary laparotomy...
September 15, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27602165/apc-promoter-is-frequently-methylated-in-pancreatic-juice-of-patients-with-pancreatic-carcinomas-or-periampullary-tumors
#15
Mireia M Ginesta, Zamira Vanessa Diaz-Riascos, Juli Busquets, Núria Pelaez, Teresa Serrano, Miquel Àngel Peinado, Rosa Jorba, Francisco Javier García-Borobia, Gabriel Capella, Joan Fabregat
Early detection of pancreatic and periampullary neoplasms is critical to improve their clinical outcome. The present authors previously demonstrated that DNA hypermethylation of adenomatous polyposis coli (APC), histamine receptor H2 (HRH2), cadherin 13 (CDH13), secreted protein acidic and cysteine rich (SPARC) and engrailed-1 (EN-1) promoters is frequently detected in pancreatic tumor cells. The aim of the present study was to assess their prevalence in pancreatic juice of carcinomas of the pancreas and periampullary area...
September 2016: Oncology Letters
https://www.readbyqxmd.com/read/27561734/isolating-tape-method-is-useful-for-an-early-judgment-of-curability-during-pancreaticoduodenectomy-for-pancreatic-cancer
#16
Shuichi Fujioka, Takeyuki Misawa, Katsuhiko Yanaga
Positive surgical margin of extrapancreatic nerve plexus (ENP) is a major cause of non-curative resection during pancreaticoduodenectomy (PD) for periampullary carcinoma (PC), which is difficult to detect at the early stage of PD. We describe a novel surgical technique using an isolating tape (iTape)-oriented ENP-first dissection (IOEFD) during PD. The iTape is firstly passed through the retroperitoneal space between ENP and inferior vena cava. Then, the iTape is further extracted from major vessels such as the common hepatic and superior mesenteric artery...
October 2016: Journal of Hepato-biliary-pancreatic Sciences
https://www.readbyqxmd.com/read/27552727/endoscopic-management-of-combined-malignant-biliary-and-gastric-outlet-obstruction
#17
Yousuke Nakai, Tsuyoshi Hamada, Hiroyuki Isayama, Takao Itoi, Kazuhiko Koike
Patients with periampullary cancer or gastric cancer often develop malignant biliary obstruction (MBO) and gastric outlet obstruction (GOO), and combined MBO and GOO is not rare in these patients. Combined MBO and GOO is classified by its location and sequence, and treatment strategy can be affected by this classification. Historically, palliative surgery, hepaticojejunostomy and gastrojejunostomy were carried out, but the current standard treatment is combined transpapillary stent and duodenal stent placement...
August 23, 2016: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/27517148/kras-mutation-as-a-prognostic-factor-in-ampullary-adenocarcinoma-a-meta-analysis-and-review
#18
Bum Jun Kim, Hyun Joo Jang, Jung Han Kim, Hyeong Su Kim, Jin Lee
Ampullary adenocarcinoma (A-AC) is a rare malignancy arising from the ampulla of Vater. KRAS mutation is detected in 30-40% of patients with A-AC, but its clinical implication and prognostic value are not well described. We conducted this meta-analysis to investigate the association between KRAS mutation and prognosis in patients with A-AC. We searched Pubmed, MEDLINE, EMBASE, and the Cochrane Library databases for articles including following terms in their titles, abstracts, or keywords: 'ampullary or periampullary or ampulla of vater', 'cancer or carcinoma', and 'KRAS'...
August 9, 2016: Oncotarget
https://www.readbyqxmd.com/read/27488532/the-genomic-landscape-of-pancreatic-and-periampullary-adenocarcinoma
#19
Vandana Sandhu, David C Wedge, Inger Marie Bowitz Lothe, Knut Jørgen Labori, Stefan C Dentro, Trond Buanes, Martina L Skrede, Astrid M Dalsgaard, Else Munthe, Ola Myklebost, Ole Christian Lingjærde, Anne-Lise Børresen-Dale, Tone Ikdahl, Peter Van Loo, Silje Nord, Elin H Kure
Despite advances in diagnostics, less than 5% of patients with periampullary tumors experience an overall survival of five years or more. Periampullary tumors are neoplasms that arise in the vicinity of the ampulla of Vater, an enlargement of liver and pancreas ducts where they join and enter the small intestine. In this study, we analyzed copy number aberrations using Affymetrix SNP 6.0 arrays in 60 periampullary adenocarcinomas from Oslo University Hospital to identify genome-wide copy number aberrations, putative driver genes, deregulated pathways, and potential prognostic markers...
September 1, 2016: Cancer Research
https://www.readbyqxmd.com/read/27484980/long-term-outcomes-and-prognostic-factors-in-periampullary-carcinoma
#20
Bhanu Jayanand Sunil, Ramakrishnan A Seshadri, S Gouthaman, Rama Ranganathan
PURPOSE: The aim of the study was to analyze the long-term survival and the various prognostic factors that influence overall survival in patients undergoing pancreaticoduodenectomy (PD) with non-pancreatic periampullary carcinomas. METHODS: A retrospective analysis of consecutive patients diagnosed with non-pancreatic periampullary carcinomas who underwent PD at a tertiary cancer center was performed. Univariate analysis of various prognostic factors influencing the disease-free survival (DFS) was performed using log-rank test...
August 3, 2016: Journal of Gastrointestinal Cancer
keyword
keyword
7430
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"