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https://www.readbyqxmd.com/read/28329327/association-of-accelerometer-measured-physical-activity-with-leukocyte-telomere-length-among-older-women
#1
Aladdin H Shadyab, Michael J LaMonte, Charles Kooperberg, Alexander P Reiner, Cara L Carty, Todd M Manini, Lifang Hou, Chongzhi Di, Andrea Z LaCroix
Background: Previous studies on physical activity and telomere length have relied largely upon self-reported physical activity data, and few studies have examined older adults. The association of objectively measured physical activity with leukocyte telomere length (LTL) is currently unknown. Methods: In this study, we examined cross-sectional associations between accelerometer-measured total, light, and moderate-to-vigorous physical activity (MVPA) and LTL, measured using Southern blot...
March 9, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/28318431/the-pursuit-of-romantic-alternatives-online-social-media-friends-as-potential-romantic-alternatives
#2
Irum Saeed Abbasi, Nawal G Alghamdi
What causes some marriages to stand the test of time while others fail? Marital commitment is the key force underlying the stability, quality, and longevity of the romantic relationship. Commitment is strengthened in the presence of marital satisfaction, the absence of alternative attractions, and steady investments made in the relationship. Commitment is also a consequence of increasing dependence such that when partners are emotionally engaged with their virtual connections, their dependence on their significant other weakens resulting in low commitment...
March 20, 2017: Journal of Sex & Marital Therapy
https://www.readbyqxmd.com/read/28302125/joint-longitudinal-data-analysis-in-detecting-determinants-of-cd4-cell-count-change-and-adherence-to-highly-active-antiretroviral-therapy-at-felege-hiwot-teaching-and-specialized-hospital-north-west-ethiopia-amhara-region
#3
Awoke Seyoum, Principal Ndlovu, Zewotir Temesgen
BACKGROUND: Adherence and CD4 cell count change measure the progression of the disease in HIV patients after the commencement of HAART. Lack of information about associated factors on adherence to HAART and CD4 cell count reduction is a challenge for the improvement of cells in HIV positive adults. The main objective of adopting joint modeling was to compare separate and joint models of longitudinal repeated measures in identifying long-term predictors of the two longitudinal outcomes: CD4 cell count and adherence to HAART...
March 16, 2017: AIDS Research and Therapy
https://www.readbyqxmd.com/read/28296573/the-adverse-effects-and-treatment-results-of-smoking-cessation-pharmacotherapy-during-fasting-non-fasting-state
#4
Sinem Iliaz, Seda Tural Onur, Mehmet Atilla Uysal, Efsun Gonca Uğur Chousein, Elif Tanriverdi, Belma Akbaba Bagci, Ayse Bahadir, Didem Gorgun Hattatoglu, Mediha Gonenc Ortakoylu, Sibel Yurt
BACKGROUND: Cigarette smoking is one of the most common addictions worldwide. Muslim smokers reduce the number of cigarettes they smoke during Ramadan due to the long fasting hours. OBJECTIVES: We aimed to share our experience in a smoking cessation clinic during Ramadan by analyzing the efficacy and adverse effects of once-daily dosing of bupropion or varenicline in a fasting group compared with conventional dosing in a non-fasting group. METHODS: We analyzed 57 patients who attended our smoking cessation clinic during Ramadan of 2014 and 2015, and at least one follow-up visit...
March 15, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28273043/frailty-and-inflammatory-markers-in-older-adults-with-cancer
#5
Tomohiro F Nishijima, Allison M Deal, Grant R Williams, Emily J Guerard, Kirsten A Nyrop, Hyman B Muss
We examined the associations between frailty and inflammatory markers, in particular neutrophil lymphocyte ratio (NLR), in elderly cancer patients. We conducted cross-sectional analyses of data derived from the Carolina Seniors Registry (CSR), a database of geriatric assessments (GA) in older adults (≧65 years) with cancer. We included patients in the CSR who had a GA and complete blood count test before initiation of therapy. The primary outcome was frailty, determined using the 36-item Carolina Frailty Index (CFI)...
March 8, 2017: Aging
https://www.readbyqxmd.com/read/28272567/-thromboelastography-useful-in-cases-of-bleeding
#6
Aurora Espinosa, Marit Seim Ekeland
Blood products are a limited resource. A number of studies have shown that the use of thromboelastography (TEG) may reduce the need for blood transfusions. The analysis can be used in acute situations in patients with massive haemorrhage as a guide to transfusion therapy. Use of TEG may play an important role in targeting transfusion therapy.
March 2017: Tidsskrift for Den Norske Lægeforening: Tidsskrift for Praktisk Medicin, Ny Række
https://www.readbyqxmd.com/read/28270029/treatment-of-intra-oral-injection-phobia-a-randomized-delayed-intervention-controlled-trial-among-norwegian-10-to-16-year-olds
#7
Karin G Berge, Maren Lillehaug Agdal, Margrethe Vika, Marit Slåttelid Skeie
OBJECTIVE: To evaluate the effect of five sessions of cognitive behavioural therapy (CBT) for 10- to 16-year-olds with intra-oral injection phobia. MATERIAL AND METHODS: This was a randomized delayed intervention controlled trial in 67 patients, fulfilling the DSM-5 criteria for specific phobia. All patients received the same CBT performed by dentists specially trained in CBT. The patients were randomly assigned to either an immediate treatment group (ITG) (34 patients) or a waitlist-control group (WCG) (33 patients)...
March 7, 2017: Acta Odontologica Scandinavica
https://www.readbyqxmd.com/read/28266821/randomized-crossover-trial-of-amoxapine-versus-vitamin-b12-for-retrograde-ejaculation
#8
Jianlin Hu, Koichi Nagao, Toshihiro Tai, Hideyuki Kobayashi, Koichi Nakajima
OBJECTIVE: To compare the efficacy and safety of amoxapine and vitamin B12 for treating retrograde ejaculation (RE). MATERIALS AND METHODS: Between May 2009 and November 2012, this open-label, randomized, crossover study enrolled 26 men suffering with RE at Department of Reproductive Medicine, Omori Hospital. Patients were randomly allocated into two groups (n=13 each). The amoxapine-B12 group received amoxapine (50 mg daily for 4 weeks, orally) followed (after a 1-week washout period) by vitamin B12 (500 μg three-times daily for 4 weeks)...
March 7, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/28240966/efficacy-of-internet-based-cognitive-behavioral-therapy-in-improving-sexual-functioning-of-breast-cancer-survivors-results-of-a-randomized-controlled-trial
#9
Susanna B Hummel, Jacques J D M van Lankveld, Hester S A Oldenburg, Daniela E E Hahn, Jacobien M Kieffer, Miranda A Gerritsma, Marianne A Kuenen, Nina Bijker, Paul J Borgstein, Gijsbert Heuff, Alexander M F Lopes Cardozo, Peter W Plaisier, Herman Rijna, Suzan van der Meij, Eric J van Dulken, Bart C Vrouenraets, Eva Broomans, Neil K Aaronson
Purpose We evaluated the effect of Internet-based cognitive behavioral therapy (CBT) on sexual functioning and relationship intimacy (primary outcomes) and body image, menopausal symptoms, marital functioning, psychological distress, and health-related quality of life (secondary outcomes) in breast cancer survivors (BCSs) with a DSM-IV diagnosis of a sexual dysfunction. Patients and Methods We randomly assigned 169 BCSs to either Internet-based CBT or a waiting-list control group. The CBT consisted of weekly therapist-guided sessions, with a maximum duration of 24 weeks...
February 27, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28237124/pharmacological-treatment-of-visuospatial-neglect-a-systematic-review
#10
REVIEW
Jet van der Kemp, Marit Dorresteijn, Antonia F Ten Brink, Tanja C W Nijboer, Johanna M A Visser-Meily
OBJECTIVES: The aims of the current review were (1) to give an overview of human studies investigating pharmacotherapy to ameliorate visuospatial neglect and (2) to evaluate the quality of those studies. METHODS: A systematic literature search using PubMed, Scopus, and ResearchGate was conducted in regard to studies that evaluated pharmacological interventions aiming to ameliorate poststroke visuospatial neglect. The search was limited in the following features: species (human), adults (≥18 years of age), language (English), and type of neglect (visuospatial)...
February 22, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28226179/the-use-of-theory-in-family-therapy-research-content-analysis-and-update
#11
Ruoxi Chen, Alexandria C Hughes, Jason P Austin
In this study, we evaluated 275 empirical studies from Journal of Marital and Family Therapy and Family Process from 2010 to 2015 on their use of theory, and compared our findings to those of a similar previous analysis (Hawley & Geske, 2000). Overall, theory seems to have become much better incorporated in empirical family therapy research, with only 16.4% of the articles not using theory in either their introductory or discussion sections. Theory appeared better incorporated in the introductory sections than in the discussion sections...
February 22, 2017: Journal of Marital and Family Therapy
https://www.readbyqxmd.com/read/28206786/posttraumatic-stress-symptoms-and-marital-adjustment-among-israeli-combat-veterans-the-role-of-loneliness-and-attachment
#12
Liat Itzhaky, Jacob Y Stein, Yafit Levin, Zahava Solomon
OBJECTIVE: War trauma may foster ramifications for marital relationships. Veterans may feel that no one can understand them and thus impact their relationships. The current study aims to shed light on the role that posttraumatic stress symptoms (PTSS), loneliness, and attachment orientations may play in marital adjustment among combat veterans. METHOD: Participants were 504 veterans who served in the Lebanon War in 1982. RESULTS: Analysis revealed that higher PTSS levels were related to lower marital adjustment and that the indirect path of this relation through loneliness was significant...
February 16, 2017: Psychological Trauma: Theory, Research, Practice and Policy
https://www.readbyqxmd.com/read/28195022/impact-of-county-level-socioeconomic-status-on-oropharyngeal-cancer-survival-in-the-united-states
#13
Uchechukwu C Megwalu
Objective To evaluate the impact of county-level socioeconomic status on survival in patients with oropharyngeal cancer in the United States. Study Design Retrospective cohort study via a large population-based cancer database. Methods Data were extracted from the SEER 18 database (Surveillance, Epidemiology, and End Results) of the National Cancer Institute. The study cohort included 18,791 patients diagnosed with oropharyngeal squamous cell carcinoma between 2004 and 2012. Results Patients residing in counties with a low socioeconomic status index had worse overall survival (56...
February 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28187212/an-analysis-of-drug-resistance-among-people-living-with-hiv-aids-in-shanghai-china
#14
Fengdi Zhang, Li Liu, Meiyan Sun, Jianjun Sun, Hongzhou Lu
BACKGROUND: Understanding the mechanisms of drug resistance can facilitate better management of antiretroviral therapy, helping to prevent transmission and decrease the morbidity and mortality of people living with HIV/AIDS. However, there is little data about transmitted drug resistance and acquired drug resistance for HIV/AIDS patients in Shanghai. METHODS: A retrospective cohort study of HIV-infected patients who visited the Department of Infectious Disease from June 2008 to June 2015 was conducted in Shanghai, China...
2017: PloS One
https://www.readbyqxmd.com/read/28156554/universal-screening-for-depression-in-cancer-patients-and-its-impact-on-management-patterns
#15
Shehzad Niazi, David Hodge, Nicolette Chimato, Ankit Agarwal, Elaine Gustetic, William Adam Hammond, Bhagirathbhai R Dholaria, Sikander Ailawadhi
232 Background: Screening for distress in cancer patients (pts) is recommended by several national guidelines. High distress scores are associated with increased depression. We established universal depression screening and investigated its impact on cancer patient management. METHODS: Patient Health Questionnaire (PHQ9) was administered to newly diagnosed cancer patients prior to receiving their first non-oral antineoplastic agent. Patient demographics, disease characteristics, chronic medication load, antidepressant use, treatment interruptions, weight change, referral and adherence to psychiatry were recorded...
October 9, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28156515/perception-of-curability-in-an-international-cohort-of-advanced-cancer-patients-receiving-palliative-care
#16
Omar M Shamieh, Luis Fernando Rodrigues, Columbe Tricou, Marilène Filbet, Kyaw Naing, Akhileswaran Ramaswamy, Mary Joycylyn S Bautista, Pedro Emilio Perez-Cruz, Sarah Fakrooden, Mary Ann Muckaden, Sofia Bunge, Vikash Sewram, Antonio Noguera Tejedor, David Hui, Minjeong Park, Diane D Liu, Eduardo Bruera
5 Background: There is limited data on the illness understanding and perception of cure among advanced cancer patients (ACP) receiving palliative care around the world. The aim of the study was to determine the frequency and factors associated with perception of curability in countries in North and South Americas , Europe, Asia and Africa. METHODS: Secondary analysis of a study to determine the decisional control preferences in different countries. ACP receiving palliative care were surveyed to assess the patients' Understanding of Illness using a Understanding Of Illness questionnaire...
October 9, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28129240/sexual-function-and-quality-of-life-among-patients-with-endometrial-cancer-after-surgery
#17
Huiqiao Gao, Meizhu Xiao, Huimin Bai, Zhenyu Zhang
OBJECTIVE: The aim of this study was to evaluate the sexual function and quality of life (QOL) and identify their associated factors in survivors of endometrial cancer. METHODS: The participants in this study were survivors of endometrial cancer who visited the gynecological outpatient department for routine surveillance from June 2014 to May 2015. The QOL and sexual function were measured using the Functional Assessment of Cancer Therapy-General (FACT-G) and Female Sexual Function Index questionnaires...
March 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28088742/patterns-of-drug-use-and-hiv-infection-among-adults-in-a-nationally-representative-sample
#18
Stephanie Shiau, Stephen M Arpadi, Michael T Yin, Silvia S Martins
BACKGROUND: Little is known about drug use patterns among people living with HIV in comparison to an uninfected group in the general population. The aim of this study was to investigate the association between legal and illegal drug use and HIV infection in a nationally representative sample of adults in the United States. METHODS: Public use data files (2005-2014) from the National Survey on Drug Use and Health (NSDUH) were used. Respondents were asked whether a medical professional had ever told them that they had HIV/AIDS...
May 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28070247/effectiveness-of-cognitive-behavioral-therapy-and-fluoxetine-on-sexual-function-of-women-with-obsessive-compulsive-disorder-a-double-blind-randomized-controlled-trial
#19
Zahra Sabetnejad, Fatemeh Assarian, Abdollah Omidi, Mohammad Reza Najarzadegan
BACKGROUND: Obsessive compulsive disorder (OCD) is a mental health concern due to its various negative consequences, especially in sexual function. Therefore, the treatment of sexual dysfunction in women with OCD is important in order to improve the patient's marital function and mental health. OBJECTIVES: To compare the sexual behavior and sexual and marital satisfaction in women with obsessive-compulsive disorder (OCD) before and after treatment with fluoxetine and cognitive behavior therapy...
November 2016: Electronic Physician
https://www.readbyqxmd.com/read/28064386/brief-supportive-expressive-group-therapy-for-partners-of-men-with-early-stage-prostate-cancer-lessons-learned-from-a-negative-randomized-controlled-trial
#20
Linda E Carlson, Codie R Rouleau, Michael Speca, John Robinson, Barry D Bultz
PURPOSE: The purpose of this paper is to report the results of a negative randomized controlled trial, which piloted brief supportive-expressive therapy (SET) for partners of men with prostate cancer, and to discuss lessons learned for future clinical trials. METHODS: Partners of men with newly diagnosed, non-metastatic prostate cancer were randomized to SET (n = 45) or usual care (n = 32). SET involved six weekly group sessions emphasizing emotional expression, social support, and finding meaning in the cancer experience...
January 7, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
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