Anke Salmen, Robert Hoepner, Vinzenz Fleischer, Milena Heldt, Barbara Gisevius, Jeremias Motte, Klemens Ruprecht, Ruth Schneider, Anna Lena Fisse, Thomas Grüter, Carsten Lukas, Achim Berthele, Katrin Giglhuber, Martina Flaskamp, Mark Mühlau, Jan Kirschke, Stefan Bittner, Sergiu Groppa, Felix Lüssi, Antonios Bayas, Sven Meuth, Cristoph Heesen, Corinna Trebst, Brigitte Wildemann, Florian Then Bergh, Gisela Antony, Tania Kümpfel, Friedemann Paul, Sandra Nischwitz, Hayrettin Tumani, Uwe Zettl, Bernhard Hemmer, Heinz Wiendl, Frauke Zipp, Ralf Gold
BACKGROUND: Depression has a major impact on the disease burden of multiple sclerosis (MS). Analyses of overlapping MS and depression risk factors [smoking, vitamin D (25-OH-VD) and Epstein-Barr virus (EBV) infection] and sex, age, disease characteristics and neuroimaging features associated with depressive symptoms in early MS are scarce. OBJECTIVES: To assess an association of MS risk factors with depressive symptoms within the German NationMS cohort. DESIGN: Cross-sectional analysis within a multicenter observational study...
2023: Therapeutic Advances in Neurological Disorders