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vitamin d and mood

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https://www.readbyqxmd.com/read/29102433/effect-of-vitamin-d-supplementation-on-non-skeletal-disorders-a-systematic-review-of-meta-analyses-and-randomised-trials
#1
REVIEW
Philippe Autier, Patrick Mullie, Alina Macacu, Miruna Dragomir, Magali Boniol, Kim Coppens, Cécile Pizot, Mathieu Boniol
Randomised trials reported up to Dec 31, 2012, did not confirm that vitamin D supplementation could protect from non-skeletal health conditions affecting adults, as was expected on the basis of data from observational studies. To examine whether the more recently published meta-analyses and trials would change past conclusions, we systematically reviewed meta-analyses of vitamin D supplementation and non-skeletal disorders published between Jan 1, 2013, and May 31, 2017, that included study participants of all ages, including pregnant women...
October 25, 2017: Lancet Diabetes & Endocrinology
https://www.readbyqxmd.com/read/29091930/self-administered-vitamin-d-status-predictor-older-adults-are-able-to-use-a-self-questionnaire-for-evaluating-their-vitamin-d-status
#2
Cedric Annweiler, Anastasiia Kabeshova, Alix Callens, Marie-Liesse Paty, Guillaume T Duval, Michael F Holick
BACKGROUND: The 16-item Vitamin D Status Predictor (VDSP) questionnaire helps to identify, without resorting to a blood test, older adults with low vitamin D concentrations. Our objective was to determine whether a self-administered VDSP was concordant with the VDSP administered by a physician, and to examine the concordance of every single item of the VDSP. METHODS: A total of 349 older in- and outpatients (mean, 83.2±7.2years; 59% female) were consecutively recruited in the geriatric ward of the University Hospital of Angers, France...
2017: PloS One
https://www.readbyqxmd.com/read/29082262/vitamin-d-supplementation-improves-mood-in-women-with-type-2-diabetes
#3
Sue Penckofer, Mary Byrn, William Adams, Mary Ann Emanuele, Patricia Mumby, Joanne Kouba, Diane E Wallis
OBJECTIVE: The aim of this study was to determine the effect of vitamin D supplementation on improving mood (depression and anxiety) and health status (mental and physical) in women with type 2 diabetes mellitus (T2DM). METHODS: Fifty women with T2DM and significant depressive symptomology were enrolled into the "Sunshine Study," where weekly vitamin D supplementation (ergocalciferol, 50,000 IU) was given to all participants for six months. The main outcomes included (1) depression (Center for Epidemiologic Studies Depression, CES-D, and Patient Health Questionnaire, PHQ-9), (2) anxiety (State-Trait Anxiety), and (3) health status (Short Form, SF-12)...
2017: Journal of Diabetes Research
https://www.readbyqxmd.com/read/28777983/vitamin-d-supplementation-in-bipolar-depression-a-double-blind-placebo-controlled-trial
#4
Wendy K Marsh, Jessica L Penny, Anthony J Rothschild
OBJECTIVE: Bipolar depression is difficult to treat. Vitamin D supplementation is well tolerated and may improve mood via its neurotransmitter synthesis regulation, nerve growth factor enhancement and antioxidant properties. Vitamin D adjunct reduces unipolar depression, but has not been tried in bipolar depression. METHODS: 18-70yos with DSM IV bipolar depression and Vitamin D deficiency (<30 ng/ml) were randomized in a controlled double blind trial of 5000IU Vitamin D3 po qday supplementation versus placebo for twelve weeks...
December 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28628270/serum-klotho-vitamin-d-and-homocysteine-in-combination-predict-the-outcomes-of-chinese-patients-with-multiple-system-atrophy
#5
Yue Guo, Xiao-Dong Zhuang, Wen-Biao Xian, Ling-Ling Wu, Ze-Na Huang, Xun Hu, Xiang-Song Zhang, Ling Chen, Xin-Xue Liao
AIMS: Neuroinflammation contributed to the pathogenesis of multiple system atrophy (MSA). We aimed to detect the correlation between inflammatory mediators, such as Klotho (Klt), vitamin D (25(OH)D) and homocysteine (Hcy), and disease severity among MSA patients. METHODS: A total of 53 MSA patients, 65 PD patients, and 62 normal subjects were recruited in our cross-sectional study. Serum Klotho (Klt), vitamin D (25(OH)D), and homocysteine (Hcy) levels were measured...
June 19, 2017: CNS Neuroscience & Therapeutics
https://www.readbyqxmd.com/read/28574478/toxoplasma-gondii-moderates-the-association-between-multiple-folate-cycle-factors-and-cognitive-function-in-u-s-adults
#6
Andrew N Berrett, Shawn D Gale, Lance D Erickson, Bruce L Brown, Dawson W Hedges
Toxoplasma gondii (T. gondii) is a microscopic, apicomplexan parasite that can infect muscle or neural tissue, including the brain, in humans. While T. gondii infection has been associated with changes in mood, behavior, and cognition, the mechanism remains unclear. Recent evidence suggests that T. gondii may harvest folate from host neural cells. Reduced folate availability is associated with an increased risk of neurodevelopmental disorders, neurodegenerative diseases, and cognitive decline. We hypothesized that impairment in cognitive functioning in subjects seropositive for T...
June 2, 2017: Nutrients
https://www.readbyqxmd.com/read/28452835/vitamin-d-status-cardiometabolic-liver-and-mental-health-status-in-obese-youth-attending-a-pediatric-weight-management-center
#7
Krista MacDonald, Kristine Godziuk, Jason Yap, Rena LaFrance, Mohammad Ansarian, Andrea Haqq, Diana R Mager
BACKGROUND: Vitamin D (VitD) deficiency and obesity are reaching epidemic proportions in North America, particularly in those with comorbid conditions such as diabetes or liver disease. The study objective was to determine the prevalence of suboptimal vitD status and interrelationships with anthropometric, cardiometabolic, liver, mental health, and lifestyle (sleep/screen time) parameters in an ambulatory population of children with obesity. METHODS: Children (2-18 years) attending a pediatric weight management clinic (n = 217) were retrospectively reviewed...
October 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28324861/behavioral-improvements-in-a-valproic-acid-rat-model-of-autism-following-vitamin-d-supplementation
#8
Lin Du, Guolian Zhao, Zipeng Duan, Fan Li
The aim was to identify the effects of early vitamin D supplementation on autism-like behaviors (ASD) induced by valproic acid (VPA, an anti-convulsant and a mood stabilizer) in rats. 10 male Wistar rat pups with prenatal exposure to saline were in control group, and 20 Pups with prenatal exposure to VPA were divided into ASD-N (0.9% saline treated) and ASD-D group (vitamin D 80,000 IU/kg treated) on postnatal day 12. Self-grooming, olfactory habituation/dishabituation, and social interaction tests were conducted to assess social interaction, communication, and repetitive behaviors...
July 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28135835/clinical-use-of-nutraceuticals-in-the-adjunctive-treatment-of-depression-in-mood-disorders
#9
Jerome Sarris
OBJECTIVES: The aim of this paper is to detail a summary of the current evidence in this area, to better inform clinical practice. Our recent systematic reviews and meta-analyses of nutrient pharmacotherapies in the treatment unipolar depression revealed primarily positive results for replicated studies testing S-adenosyl methionine (SAMe), methylfolate, omega-3 (EPA or ethyl-EPA), and Vitamin D; with supportive isolated studies found for creatine and an amino acid combination. Mixed results were found for zinc, folic acid, Vitamin C, and tryptophan; and non-significant study results for inositol...
August 2017: Australasian Psychiatry: Bulletin of Royal Australian and New Zealand College of Psychiatrists
https://www.readbyqxmd.com/read/28075425/management-of-fibromyalgia-practical-guides-from-recent-evidence-based-guidelines
#10
REVIEW
Winfried Häuser, Jacob Ablin, Serge Perrot, Mary-Ann Fitzcharles
Fibromyalgia (FM) is a prevalent and costly condition worldwide, affecting approximately 2% of the general population. Recent evidence- and consensus‑based guidelines from Canada, Germany, Israel, and the European League Against Rheumatism aim to support physicians in achieving a comprehensive diagnostic workup of patients with chronic widespread (generalized) pain (CWP) and to assist patients and physicians in shared decision making on treatment options. Every patient with CWP requires, at the first medical evaluation, a complete history, medical examination, and some laboratory tests (complete blood count, measurement of C‑reactive protein, serum calcium, creatine phosphokinase, thyroid‑stimulating hormone, and 25‑hydroxyvitamin D levels) to screen for metabolic or inflammatory causes of CWP...
January 4, 2017: Polish Archives of Internal Medicine
https://www.readbyqxmd.com/read/28068788/a-double-blind-randomized-placebo-controlled-trial-of-lactobacillus-helveticus-and-bifidobacterium-longum-for-the-symptoms-of-depression
#11
Amy R Romijn, Julia J Rucklidge, Roeline G Kuijer, Chris Frampton
OBJECTIVES: This trial investigated whether probiotics improved mood, stress and anxiety in a sample selected for low mood. We also tested whether the presence or severity of irritable bowel syndrome symptoms, and levels of proinflammatory cytokines, brain-derived neurotrophic factor and other blood markers, would predict or impact treatment response. METHOD: Seventy-nine participants (10 dropouts) not currently taking psychotropic medications with at least moderate scores on self-report mood measures were randomly allocated to receive either a probiotic preparation (containing Lactobacillus helveticus and Bifidobacterium longum) or a matched placebo, in a double-blind trial for 8 weeks...
August 2017: Australian and New Zealand Journal of Psychiatry
https://www.readbyqxmd.com/read/28012571/perinatal-nutrition-interventions-and-post-partum-depressive-symptoms
#12
REVIEW
Jacqueline F Gould, Karen Best, Maria Makrides
BACKGROUND: Postpartum depression (PPD) is the most prevalent mood disorder associated with childbirth. No single cause of PPD has been identified, however the increased risk of nutritional deficiencies incurred through the high nutritional requirements of pregnancy may play a role in the pathology of depressive symptoms. Three nutritional interventions have drawn particular interest as possible non-invasive and cost-effective prevention and/or treatment strategies for PPD; omega-3 (n-3) long chain polyunsaturated fatty acids (LCPUFA), vitamin D and overall diet...
December 15, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27993842/exercise-induced-biochemical-changes-and-their-potential-influence-on-cancer-a-scientific-review
#13
REVIEW
Robert James Thomas, Stacey A Kenfield, Alfonso Jimenez
AIM: To review and discuss the available international literature regarding the indirect and direct biochemical mechanisms that occur after exercise, which could positively, or negatively, influence oncogenic pathways. METHODS: The PubMed, MEDLINE, Embase and Cochrane libraries were searched for papers up to July 2016 addressing biochemical changes after exercise with a particular reference to cancer. The three authors independently assessed their appropriateness for inclusion in this review based on their scientific quality and relevance...
April 2017: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/27975236/impact-of-high-dose-vitamin-d3-supplementation-in-patients-with-crohn-s-disease-in-remission-a-pilot-randomized-double-blind-controlled-study
#14
RANDOMIZED CONTROLLED TRIAL
Neeraj Narula, Mohan Cooray, Rebecca Anglin, Zack Muqtadir, Alisha Narula, John K Marshall
AIM: To assess the tolerability and efficacy of high-dose vitamin D3 in patients with Crohn's disease (CD). METHODS: This was a randomized, double-blind placebo-controlled trial of high-dose vitamin D3 at 10,000 IU daily (n = 18) compared to 1000 IU daily (n = 16) for 12 months in patients with CD in remission. The primary outcome was change in serum 25-hydroxy-vitamin D levels. Secondary outcomes included clinical relapse rates and changes in mood scores...
February 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/27827293/vitamin-d-deficiency-behavioral-atypicality-anxiety-and-depression-in-children-with-chromosome-22q11-2-deletion-syndrome
#15
L Kelley, A F P Sanders, E A Beaton
Chromosome 22q11.2 deletion syndrome (22q11.2DS) is a complex developmental disorder with serious medical, cognitive and emotional symptoms across the lifespan. This genetic deletion also imparts a lifetime risk for developing schizophrenia that is 25-30 times that of the general population. The origin of this risk is multifactorial and may include dysregulation of the stress response and immunological systems in relation to brain development. Vitamin D is involved in brain development and neuroprotection, gene transcription, immunological regulation and influences neuronal signal transduction...
December 2016: Journal of Developmental Origins of Health and Disease
https://www.readbyqxmd.com/read/27810275/serum-25-hydroxyvitamin-d-and-mental-health-in-young-australian-women-results-from-the-safe-d-study
#16
Emma T Callegari, Nicola Reavley, Alexandra Gorelik, Suzanne M Garland, John D Wark
BACKGROUND: While there is evidence linking vitamin D status with mood, this association and its clinical significance remain uncertain. Moreover, few studies have focused on young, community-dwelling females. The Safe-D study examined the association between serum 25-hydroxyvitamin D (25OHD) levels and mental health in young women. METHODS: Participants completed an online questionnaire, wore a UV dosimeter to measure personal sun exposure and underwent a comprehensive health assessment...
December 15, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27792133/effects-of-walnut-consumption-on-mood-in-young-adults-a-randomized-controlled-trial
#17
RANDOMIZED CONTROLLED TRIAL
Peter Pribis
Walnuts contain a number of potentially neuroprotective compounds like vitamin E, folate, melatonin, several antioxidative polyphenols and significant amounts of ω-3 fatty acids. The present study sought to determine the effect of walnuts on mood in healthy volunteers. Sixty-four college students were randomly assigned to two treatment sequences in a crossover fashion: walnut-placebo or placebo-walnut. At baseline mood was assessed using Profiles of Mood States (POMS). Data was collected again after eight weeks of intervention...
October 25, 2016: Nutrients
https://www.readbyqxmd.com/read/27716304/appropriate-vitamin-d-loading-regimen-for-patients-with-advanced-lung-cancer
#18
L John Hoffer, Line Robitaille, Nelda Swinton, Jason Agulnik, Victor Cohen, David Small, Carmela Pepe, Shaun Eintracht
BACKGROUND: Most patients attending cancer clinics have hypovitaminosis D. Correcting or preventing this abnormal condition could mitigate the emotional and physical complications of their disease, but clinical trials of vitamin D therapy in this setting are hindered by the unavailability of safe, effective and practical loading dose regimens. METHODS: In this single arm open-label pharmacokinetic trial, outpatients with advanced lung cancer consumed 20,000 IU vitamin D daily with the largest meal of the day for 14 days followed by 10,000 IU per day for a further 7 days...
October 6, 2016: Nutrition Journal
https://www.readbyqxmd.com/read/27672750/the-effect-of-vitamin-d-supplementation-on-pain-mood-depression-and-strength-in-patients-with-spinal-cord-injury
#19
Thornton G Williams, Reza Ehsanian, Kazuko L Shem, Jerry Wright, Linda Isaac, James Crew
No abstract text is available yet for this article.
September 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/27612362/fatty-acid-blood-levels-vitamin-d-status-physical-performance-activity-and-resiliency-a-novel-potential-screening-tool-for-depressed-mood-in-active-duty-soldiers
#20
Nicholas D Barringer, Russ S Kotwal, Michael D Lewis, Leslee K Funderburk, Timothy R Elliott, Stephen F Crouse, Stephen B Smith, Michael Greenwood, Richard B Kreider
This study examined whether blood fatty acid levels, vitamin D status, and/or physical activity are associated with physical fitness scores; a measure of mood, Patient Health Questionnaire-9; and a measure of resiliency, Dispositional Resiliency Scale-15 in active duty Soldiers. 100 active duty males at Fort Hood, Texas, underwent a battery of psychometric tests, anthropometric measurements, and fitness tests, and they also provided fasting blood samples for fatty acid and vitamin D analysis. Pearson bivariate correlation analysis revealed significant correlations among psychometric tests, anthropometric measurements, physical performance, reported physical inactivity (sitting time), and fatty acid and vitamin D blood levels...
September 2016: Military Medicine
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