Read by QxMD icon Read

Malaria and panama

Andrés López-Rubio, Juan Suaza-Vasco, Paula L Marcet, Natalia Ruíz-Molina, Lorenzo Cáceres, Charles Porter, Sandra Uribe
A reference 535 bp barcode sequence from a fragment of the mitochondrial gene cytochrome oxidase I (COI), acquired from specimens of An. neivai Howard, Dyar & Knab, 1913 from its type locality in Panama, was used as a tool for distinguishing this species from others in the subgenus Kerteszia. Comparisons with corresponding regions of COI between An. neivai and other species in the subgenus (An. bellator Dyar & Knab 1906, An. homunculus Komp 1937, An cruzii Dyar & Knab, 1908 and An. laneanus Corrêa & Cerqueira, 1944) produced K2P genetic distances of 8...
October 17, 2016: Zootaxa
William Lainhart, Larissa C Dutari, Jose R Rovira, Izis M C Sucupira, Marinete M Póvoa, Jan E Conn, Jose R Loaiza
From 2002-2005, Panama experienced a malaria epidemic that has been associated with El Niño Southern Oscillation weather patterns, decreased funding for malaria control, and landscape modification. Case numbers quickly decreased afterward, and Panama is now in the pre-elimination stage of malaria eradication. To achieve this new goal, the characterization of epidemiological risk factors, foci of transmission, and important anopheline vectors is needed. Of the 24,681 reported cases in these analyses (2000-2014), ~62% occurred in epidemic years and ~44% in indigenous comarcas (5...
May 2016: PLoS Neglected Tropical Diseases
Macarthur Charles, Sanchita Das, Rachel Daniels, Laura Kirkman, Glavdia G Delva, Rodney Destine, Ananias Escalante, Leopoldo Villegas, Noah M Daniels, Kristi Shigyo, Sarah K Volkman, Jean W Pape, Linnie M Golightly
Hispaniola is the only Caribbean island to which Plasmodium falciparum malaria remains endemic. Resistance to the antimalarial drug chloroquine has rarely been reported in Haiti, which is located on Hispaniola, but the K76T pfcrt (P. falciparum chloroquine resistance transporter) gene mutation that confers chloroquine resistance has been detected intermittently. We analyzed 901 patient samples collected during 2006-2009 and found 2 samples showed possible mixed parasite infections of genetically chloroquine-resistant and -sensitive parasites...
May 2016: Emerging Infectious Diseases
Margarita Griffith, José Rovira, Rolando Torres, José Calzada, Carlos Victoria, Lorenzo Cáceres
INTRODUCTION: Knowledge, attitudes and practices surveys allow to determine the degree of knowledge on the management of malaria in a given population, as well as the attitudes and practices that contribute or not to its transmission. OBJECTIVE: To identify the knowledge, attitudes and practices that favor or not the transmission of malaria in the indigenous Guna population of Madungandí. MATERIALS AND METHODS: A cross-sectional study was conducted by applying a survey to the heads of the families in a sample of 40% of households in three communities with high malaria incidence...
October 2015: Biomédica: Revista del Instituto Nacional de Salud
José E Calzada, Ricardo Marquez, Chystrie Rigg, Carlos Victoria, Manuel De La Cruz, Luis F Chaves, Lorenzo Cáceres
BACKGROUND: This study aims to describe the epidemiological and entomological factors associated with a recent malaria outbreak that occurred in 2012 in a socially marginalized population from Guna Yala Comarca in Panama. METHODS: A descriptive and observational study was conducted by analysing demographic and epidemiological data from all malaria cases registered during 2012 in the Comarca Guna Yala, Panama. Malaria intensity indicators were calculated during the study period...
2015: Malaria Journal
Giovan F Gómez, Sara A Bickersmith, Ranulfo González, Jan E Conn, Margarita M Correa
Phylogenetic analysis of partial mitochondrial cytochrome oxidase c subunit I (COI) and nuclear internal transcribed spacer 2 (ITS2) sequences were used to evaluate initial identification and to investigate phylogenetic relationships of seven Anopheles morphospecies of the Arribalzagia Series from Colombia. Phylogenetic trees recovered highly supported clades for An. punctimaculas.s., An. calderoni, An. malefactor s.l., An. neomaculipalpus, An. apicimacula s.l., An. mattogrossensis and An. peryassui. This study provides the first molecular confirmation of An...
2015: PloS One
Nicanor Obaldia
BACKGROUND: Identification of risk factors is important for the establishment of malaria elimination programmes tailored to specific regions. Type of house construction had been associated with increasing risk of acquiring malaria. This study aimed at establishing the association between determinants of low socio-economic status (SES) and type of house construction with the likelihood of living in a Plasmodium vivax malarious corregimiento (smallest political division) in Panama during 2009-2012...
2015: Malaria Journal
Nicanor Obaldia, Nicholas K Baro, Jose E Calzada, Ana M Santamaria, Rachel Daniels, Wesley Wong, Hsiao-Han Chang, Elizabeth J Hamilton, Myriam Arevalo-Herrera, Socrates Herrera, Dyann F Wirth, Daniel L Hartl, Matthias Marti, Sarah K Volkman
Identifying the source of resurgent parasites is paramount to a strategic, successful intervention for malaria elimination. Although the malaria incidence in Panama is low, a recent outbreak resulted in a 6-fold increase in reported cases. We hypothesized that parasites sampled from this epidemic might be related and exhibit a clonal population structure. We tested the genetic relatedness of parasites, using informative single-nucleotide polymorphisms and drug resistance loci. We found that parasites were clustered into 3 clonal subpopulations and were related to parasites from Colombia...
April 1, 2015: Journal of Infectious Diseases
Peter J Hotez, Laila Woc-Colburn, Maria Elena Bottazzi
A review of the literature since 2009 reveals a staggering health and economic burden resulting from neglected tropical diseases in Panama and the six countries of Central America (referred to collectively here as 'Central America'). Particularly at risk are the 10.2million people in the region who live on less than $2 per day, mostly in Guatemala, Honduras, Nicaragua and El Salvador. Indigenous populations are especially vulnerable to neglected tropical diseases. Currently, more than 8million Central American children require mass drug treatments annually (or more frequently) for their intestinal helminth infections, while vector-borne diseases are widespread...
August 2014: International Journal for Parasitology
Paige Sachs, Gloria Alicia Diaz Rodriguez, Ireneo Briceno, Russell King, Nicole L Achee, John P Grieco
Anopheles darlingi is a major vector for malaria in Central and South America. Behavioral, ecological, genetic, and morphologic variability has been observed across its wide distribution. Recent studies have documented that 2 distinct genotypes exist for An. darlingi: a northern lineage (Belize, Guatemala, Colombia, Venezuela, and Panama) and a southern lineage (Amazonia and southern Brazil). In order to determine if these genotypes exhibited different behavioral traits, entrance and exit movement patterns between 2 field populations of An...
December 2013: Journal of the American Mosquito Control Association
Sarah Higginbotham, Weng Ruh Wong, Roger G Linington, Carmenza Spadafora, Liliana Iturrado, A Elizabeth Arnold
The extraordinary biological diversity of tropical forests harbors a rich chemical diversity with enormous potential as a source of novel bioactive compounds. Of particular interest are new environments for microbial discovery. Sloths--arboreal mammals commonly found in the lowland forests of Panama--carry a wide variety of micro- and macro-organisms on their coarse outer hair. Here we report for the first time the isolation of diverse and bioactive strains of fungi from sloth hair, and their taxonomic placement...
2014: PloS One
Sarah J Higginbotham, A Elizabeth Arnold, Alicia Ibañez, Carmenza Spadafora, Phyllis D Coley, Thomas A Kursar
Fungal endophytes--fungi that grow within plant tissues without causing immediate signs of disease--are abundant and diverse producers of bioactive secondary metabolites. Endophytes associated with leaves of tropical plants are an especially exciting and relatively untapped source of novel compounds. However, one major challenge in drug discovery lies in developing strategies to efficiently recover highly bioactive strains. As part of a 15-year drug discovery project, foliar endophytes were isolated from 3198 plant samples (51 orders, 105 families and at least 232 genera of angiosperms and ferns) collected in nine geographically distinct regions of Panama...
2013: PloS One
Jose R Loaiza, Matthew J Miller
Aedeomyia squamipennis and Culex (Melanoconion) ocossa, two ubiquitous Neotropical mosquito species, are likely involved in the transmission of several bird pathogens in Gamboa, central Panama. However, knowledge on their eco-epidemiological profiles is still incomplete. Our goal in this study was to investigate temporal trends of vector density and their relationship with avian plasmodia prevalence. This information is central to identifying the risk posed by each vector species to the avian community locally...
November 2013: Parasitology Research
Jose R Loaiza, Marilyn E Scott, Eldredge Bermingham, Oris I Sanjur, Jose R Rovira, Larissa C Dutari, Yvonne-Marie Linton, Sara Bickersmith, Jan E Conn
Anopheles punctimacula s.l. is a regional malaria vector in parts of Central America, but its role in transmission is controversial due to its unresolved taxonomic status. Two cryptic species, An. malefactor and An. calderoni, have been previously confused with this taxon, and evidence for further genetic differentiation has been proposed. In the present study we collected and morphologically identified adult female mosquitoes of An. punctimacula s.l. from 10 localities across Panama and one in Costa Rica. DNA sequences from three molecular regions, the three prime end of the mitochondrial cytochrome c oxidase I gene (3' COI), the Barcode region in the five prime end of the COI (5' COI), and the rDNA second internal transcribed spacer (ITS2) were used to test the hypothesis of new molecular lineages within An...
October 2013: Acta Tropica
Lorenzo Cáceres, José Rovira, Rolando Torres, Arsenio García, José Calzada, Manuel De La Cruz
INTRODUCTION: Few studies have described the factors associated with Plasmodium vivax transmission dynamics in endemic regions from Panamá. OBJECTIVE: Malaria transmission dynamics produced by P. vivax were characterized at the border between Panamá and Costa Rica. MATERIALS AND METHODS: In the municipality of Barú, an observational, descriptive and cross-sectional study was undertaken to measure the annual parasite index (API), slide positivity index (SPR), and the annual blood examination rate (ABER)...
October 2012: Biomédica: Revista del Instituto Nacional de Salud
Lorenzo Cáceres, José Rovira, Arsenio García, Rolando Torres
INTRODUCTION: The susceptibility of Anopheles albimanus to organophosphates, carbamates and pyrethroid insecticides was unknown in the Panama communities of Aguas Claras, Pintupo and Puente Bayano, located in the Amerindian Reservation of Madungandi. This region is considered a malaria transmission area, where An. albimanus is the main vector. OBJECTIVE: The resistance to organophosphate insecticides, carbamates and pyrethroids was evaluated in field populations of the Anopheles albimanus in Panama...
July 2011: Biomédica: Revista del Instituto Nacional de Salud
Angela I Calderón, Johayra Simithy-Williams, Mahabir P Gupta
CONTEXT: Malaria is still a major public health problem. The biodiversity of the tropics is extremely rich and represents an invaluable source of novel bioactive molecules. For screening of this diversity more sensitive and economical in vitro methods are needed, Flora of Panama has been studied based on ethnomedical uses for discovering antimalarial compounds. OBJECTIVE: This review aims to provide an overview of in vitro screening methodologies for antimalarial drug discovery and to present results of this effort in Panama during the last quarter century...
January 2012: Pharmaceutical Biology
Surendra K Prajapati, Hema Joshi, Sneh Shalini, Manuel A Patarroyo, Rossarin Suwanarusk, Ashwani Kumar, Surya K Sharma, Alex Eapen, Vas Dev, Rajendra M Bhatt, Neena Valecha, Francois Nosten, Moshahid A Rizvi, Aditya P Dash
BACKGROUND: Multi-drug resistance and severe/complicated cases are the emerging phenotypes of vivax malaria, which may deteriorate current anti-malarial control measures. The emergence of these phenotypes could be associated with either of the two Plasmodium vivax lineages. The two lineages had been categorized as Old World and New World, based on geographical sub-division and genetic and phenotypical markers. This study revisited the lineage hypothesis of P. vivax by typing the distribution of lineages among global isolates and evaluated their genetic relatedness using a panel of new mini-satellite markers...
2011: Malaria Journal
Eufemio Moreno, Titto Varughese, Carmenza Spadafora, A Elizabeth Arnold, Phyllis D Coley, Thomas A Kursar, William H Gerwick, Luis Cubilla-Rios
Chemical investigation of a new endophytic fungus, Mycosphaerella sp. nov. strain F2140, associated with the foliage of the plant Psychotria horizontalis (Rubiaceae) in Panama, resulted in the isolation of cercosporin (1) and a new cercosporin analog (3) as the major components. The structures of minor compounds in the extract were elucidated by detailed spectroscopic analysis as 2-(2-butyl)-6-ethyl-3-hydroxy-6-methylcyclohex-2-ene-1,5-dione (4), 3-(2-butyl)-6-ethyl-5-hydroxy-2-methoxy-6-methyl-cyclohex-2-enone (5), and an isomer of 5 (6)...
June 2011: Natural Product Communications
Nicanor Obaldia, William Otero, Camilo Marin, Jorge Aparicio, Gloria Cisneros
BACKGROUND: The long-term effect of a PVC pipe nest-box on the reproductive efficiency and other life traits of an Aotus monkey-breeding colony have not been characterized. METHODS AND RESULTS: We analyzed laboratory records of the Gorgas Memorial Institute (GMI) Aotus monkey colony in Panama for the period 1999-2010 and found a 273% increase in the annual mean life births in the following 7 years after the introduction of a PVC pipe nest-box in 2002, as well as increases in the mean body mass and survival of laboratory-bred monkeys...
December 2011: Journal of Medical Primatology
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"