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https://www.readbyqxmd.com/read/29339480/local-policy-proposals-can-bridge-latino-and-most-white-americans-response-to-immigration
#1
Yuen J Huo, John F Dovidio, Tomás R Jiménez, Deborah J Schildkraut
In the past 15 years, the adoption of subnational immigration policies in the United States, such as those established by individual states, has gone from nearly zero to over 300 per year. These include welcoming policies aimed at attracting and incorporating immigrants, as well as unwelcoming policies directed at denying immigrants access to public resources and services. Using data from a 2016 random digit-dialing telephone survey with an embedded experiment, we examine whether institutional support for policies that are either welcoming or hostile toward immigrants differentially shape Latinos' and whites' feelings of belonging in their state (Arizona/New Mexico, adjacent states with contrasting immigration policies)...
January 16, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29336559/investigation-on-two-forms-of-temperature-sensing-parameters-for-fluorescence-intensity-ratio-thermometry-based-on-thermal-coupled-theory
#2
Mochen Jia, Guofeng Liu, Zhen Sun, Zuoling Fu, Weiguo Xu
Absolute temperature sensitivity (Sa) reflects the precision of sensors that belong to the same mechanism, whereas relative temperature sensitivity (Sr) is used to compare sensors from different mechanisms. For the fluorescence intensity ratio (FIR) thermometry based on two thermally coupled energy levels of one rare earth (RE) ion, we define a new ratio as the temperature-sensing parameter that can vary greatly with temperature in some circumstances, which can obtain higher Sa without changing Sr. Further discussion is made on the conditions under which these two forms of temperature-sensing parameters can be used to achieve higher Sa for biomedical temperature sensing...
January 16, 2018: Inorganic Chemistry
https://www.readbyqxmd.com/read/29336337/-training-program-in-endourological-surgery-future-perspectives
#3
Federico Soria, Felipe Villacampa, Alvaro Serrano, Jesús Moreno, Jorge Rioja, Francisco Miguel Sánchez
Current training in urological endoscopy lacks a specific training program. However, there is a clear need for a specific and uniform program, which will ensure the training, regardless of the unit where it is carried out. So, the goal is to first evaluate the current model and then bring improvements for update. The hospital training accreditation programme are only the adjustment of the official program of the urology specialty to the specific circumstances of each center, which causes variability in training of residents...
January 2018: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/29333037/curcumin-and-natural-derivatives-inhibit-ebola-viral-proteins-an-in-silico-approach
#4
Shruti Baikerikar
Background: Ebola viral disease is a severe and mostly fatal disease in humans caused by Ebola virus. This virus belongs to family Filoviridae and is a single-stranded negative-sense virus. There is no single treatment for this disease which puts forth the need to identify new therapy to control and treat this fatal condition. Curcumin, one of the bioactives of turmeric, has proven antiviral property. Objective: The current study evaluates the inhibitory activity of curcumin, bisdemethoxycurcumin, demethoxycurcumin, and tetrahydrocurcumin against Zaire Ebola viral proteins (VPs)...
December 2017: Pharmacognosy Research
https://www.readbyqxmd.com/read/29332802/total-%C3%AE-1-acid-glycoprotein-determination-in-serum-samples-using-disposable-screen-printed-electrodes-and-osmium-vi-as-electrochemical-tag
#5
Tania Sierra, María Cristina González, Begoña Moreno, Agustin G Crevillen, Alberto Escarpa
Alpha-1-acid glycoprotein (AGP) or Orosomucoid is a serum glycoprotein which belongs to the group of acute phase proteins. It is a potential biomarker for inflammatory bowel diseases. In this sense, there is a need for developing fast and cheap analytical methods for diagnosis, prognosis and follow-up of these diseases. In this work, we propose a simple and cheap electrochemical method for total AGP determination using disposable carbon screen-printed electrodes (SPE) and using a selective acidic precipitation of the rest of proteins...
April 1, 2018: Talanta
https://www.readbyqxmd.com/read/29326102/collectively-improving-our-teaching-attempting-biology-department-wide-professional-development-in-scientific-teaching
#6
Melinda T Owens, Gloriana Trujillo, Shannon B Seidel, Colin D Harrison, Katherine M Farrar, Hilary P Benton, J R Blair, Katharyn E Boyer, Jennifer L Breckler, Laura W Burrus, Dana T Byrd, Natalia Caporale, Edward J Carpenter, Yee-Hung M Chan, Joseph C Chen, Lily Chen, Linda H Chen, Diana S Chu, William P Cochlan, Robyn J Crook, Karen D Crow, José R de la Torre, Wilfred F Denetclaw, Lynne M Dowdy, Darleen Franklin, Megumi Fuse, Michael A Goldman, Brinda Govindan, Michael Green, Holly E Harris, Zheng-Hui He, Stephen B Ingalls, Peter Ingmire, Amber R B Johnson, Jonathan D Knight, Gretchen LeBuhn, Terrye L Light, Candace Low, Lance Lund, Leticia M Márquez-Magaña, Vanessa C Miller-Sims, Christopher A Moffatt, Heather Murdock, Gloria L Nusse, V Thomas Parker, Sally G Pasion, Robert Patterson, Pleuni S Pennings, Julio C Ramirez, Robert M Ramirez, Blake Riggs, Rori V Rohlfs, Joseph M Romeo, Barry S Rothman, Scott W Roy, Tatiane Russo-Tait, Ravinder N M Sehgal, Kevin A Simonin, Greg S Spicer, Jonathon H Stillman, Andrea Swei, Leslie C Tempe, Vance T Vredenburg, Steven L Weinstein, Andrew G Zink, Loretta A Kelley, Carmen R Domingo, Kimberly D Tanner
Many efforts to improve science teaching in higher education focus on a few faculty members at an institution at a time, with limited published evidence on attempts to engage faculty across entire departments. We created a long-term, department-wide collaborative professional development program, Biology Faculty Explorations in Scientific Teaching (Biology FEST). Across 3 years of Biology FEST, 89% of the department's faculty completed a weeklong scientific teaching institute, and 83% of eligible instructors participated in additional semester-long follow-up programs...
2018: CBE Life Sciences Education
https://www.readbyqxmd.com/read/29316047/parainfluenza-virus-5-vectored-vaccines-against-human-and-animal-infectious-diseases
#7
REVIEW
Zhenhai Chen
Parainfluenza virus 5 (PIV5), known as canine parainfluenza virus in the veterinary field, is a negative-sense, nonsegmented, single-stranded RNA virus belonging to the Paramyxoviridae family. Parainfluenza virus 5 is an excellent viral vector and has been used as a live vaccine for kennel cough for many years in dogs without any safety concern. It can grow to high titers in many cell types, and its genome is stable even in the presence of foreign gene insertions. So far, PIV5 has been used to develop vaccines against influenza virus, respiratory syncytial virus, rabies virus, and Mycobacterium tuberculosis, demonstrating its ability to elicit robust and protective immune responses in preclinical animal models...
January 5, 2018: Reviews in Medical Virology
https://www.readbyqxmd.com/read/29302574/nurses-attitude-towards-professionalization-and-factors-influencing-it
#8
Masoumeh Shohani, Vahid Zamanzadeh
Introduction: Professionalism is one of the fundamental concepts in nursing and the result of the interaction with the environment and others. Nursing professionalism influences the quality of care and is affected by several factors. This study aimed to determine the attitude of nurses regarding professionalism and the factors affecting it. Methods: In this descriptive study, the attitude among nurses to professionalism has been measured through the questionnaire Hall, in five dimensions "membership in professional organizations", "public service", "a sense of calling", "self-regulation"," autonomy" and a researcher-made questionnaire about effective factors...
December 2017: Journal of Caring Sciences
https://www.readbyqxmd.com/read/29299996/consumer-perception-of-sustainability-attributes-in-organic-and-local-food
#9
Azzurra Annunziata
BACKGROUND: Although sustainable food consumption is gaining growing importance on the international agenda, research on this subject is still quite fragmented and most studies analyse single aspects of sustainable food consumption with particular reference to environmental sustainability. In addition, the literature highlights the need to take account of the strong heterogeneity of consumers in studying sustainable behaviour. Identifying consumer segments with common profiles, needs and values is essential for developing effective communication strategies to promote sustainability in food consumption...
December 14, 2017: Recent Patents on Food, Nutrition & Agriculture
https://www.readbyqxmd.com/read/29281637/cell-envelope-stress-in-mycobacteria-is-regulated-by-the-novel-signal-transduction-atpase-inir-in-response-to-trehalose
#10
Maikel Boot, Vincent J C van Winden, Marion Sparrius, Robert van de Weerd, Alexander Speer, Roy Ummels, Tige Rustad, David R Sherman, Wilbert Bitter
The cell envelope of mycobacteria is a highly unique and complex structure that is functionally equivalent to that of Gram-negative bacteria to protect the bacterial cell. Defects in the integrity or assembly of this cell envelop must be sensed to allow the induction of stress response systems. The promoter that is specifically and most strongly induced upon exposure to ethambutol and isoniazid, first line drugs that affect cell envelope biogenesis, is the iniBAC promoter. In this study, we set out to identify the regulator of the iniBAC operon in Mycobacterium marinum using an unbiased transposon mutagenesis screen in a constitutively iniBAC-expressing mutant background...
December 27, 2017: PLoS Genetics
https://www.readbyqxmd.com/read/29278248/when-the-spell-is-broken-gentrification-urban-tourism-and-privileged-discontent-in-the-amsterdam-canal-district
#11
Fenne M Pinkster, Willem R Boterman
Expansion of urban tourism in historic districts in European cities is putting increasing pressure on these areas as places to live. In Amsterdam, an ever-growing number of tourists visit the famous canal district, which also forms the home of a group of long-term, upper-middle-class residents. While such residents are generally depicted as instigators of urban transformation, in this case, they are on the receiving end. Bringing together the literature on the socio-spatial impact of tourism, belonging and the lived experience of place, this article explores the changing relationship between these established residents and their neighbourhood and provides insight into their growing sense of discontent and even powerlessness in the face of neighbourhood change...
July 2017: Cult Geogr
https://www.readbyqxmd.com/read/29274419/an-overview-of-the-immune-modulating-effects-of-enzymatic-toxins-from-snake-venoms
#12
REVIEW
Sandra M Burin, Danilo L Menaldo, Suely V Sampaio, Fabiani G Frantz, Fabíola A Castro
Snake venoms are complex mixtures of organic and inorganic compounds, including proteins belonging to the protease (serine and metalloproteinases), oxidase (L-amino acid oxidases), and phospholipase (especially phospholipases A2) enzyme classes. These toxins account for the serious deleterious effects of snake envenomations, such as tissue necrosis, neurotoxicity, and hemorrhage. In addition to their toxic effects, snake venom toxins have served as important tools for investigating the mechanisms underlying envenomation and discovering new pharmacologically active compounds with immunotherapeutic potential...
December 20, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29251060/ethnic-density-of-regions-and-psychiatric-disorders-among-ethnic-minority-individuals
#13
Scott Daniel Emerson, Anita Minh, Martin Guhn
BACKGROUND: Ethnic minorities form an increasingly large proportion of Canada's population. Living in areas of greater ethnic density may help protect mental health among ethnic minorities through psychosocial pathways such as accessibility to culturally appropriate provision of mental health care, less discrimination and a greater sense of belonging. Mood and anxiety disorders are common psychiatric disorders. AIM: This study examined whether ethnic density of regions was related to mood and anxiety disorders among ethnic minorities in Canada...
December 1, 2017: International Journal of Social Psychiatry
https://www.readbyqxmd.com/read/29248385/a-cytosolic-sensor-pmddx41-mediates-antiviral-immune-response-in-black-tiger-shrimp-penaeus-monodon
#14
Suthinee Soponpong, Piti Amparyup, Anchalee Tassanakajon
DEAD (Asp-Glu-Ala-Asp)-box polypeptide 41 (DDX41), a receptor belonging to the DExD family, has recently been identified as an intracellular DNA sensor in vertebrates. Here, we report on the identification and functional characterization of PmDDX41, the first cytosolic DNA sensor in shrimp. By searching a Penaeus monodon expressed sequence tag (EST) database (http://pmonodon.biotec.or.th), three cDNA fragments exhibiting similarity to DDX41 in various species were identified and assembled, resulting in a complete open reading frame of PmDDX41 that contains 1868-bp and encodes a putative protein of 620 amino acids...
December 14, 2017: Developmental and Comparative Immunology
https://www.readbyqxmd.com/read/29245518/a-new-species-of-the-i-chaleponcus-i-i-dabagaensis-i-group-from-mount-rungwe-tanzania-support-for-an-extended-concept-of-the-eastern-arc-mountains-diplopoda-spirostreptida-odontopygidae
#15
Henrik Enghoff
Chaleponcus altirungwensis sp. nov. is described from Mount Rungwe, Tanzania. The new species belongs to the Chaleponcus dabagaensis group which is otherwise restricted to the Udzungwa Mountains and joins a growing set of taxa indicating close biogeographical connections between Mount Rungwe and the Eastern Arc Mountains in a strict sense.
November 23, 2017: Zootaxa
https://www.readbyqxmd.com/read/29235472/a-ph-gated-conformational-switch-regulates-the-phosphatase-activity-of-bifunctional-hiska-family-histidine-kinases
#16
Yixiang Liu, Joshua Rose, Shaojia Huang, Yangbo Hu, Qiong Wu, Dan Wang, Conggang Li, Maili Liu, Pei Zhou, Ling Jiang
Histidine kinases are key regulators in the bacterial two-component systems that mediate the cellular response to environmental changes. The vast majority of the sensor histidine kinases belong to the bifunctional HisKA family, displaying both kinase and phosphatase activities toward their substrates. The molecular mechanisms regulating the opposing activities of these enzymes are not well understood. Through a combined NMR and crystallographic study on the histidine kinase HK853 and its response regulator RR468 from Thermotoga maritima, here we report a pH-mediated conformational switch of HK853 that shuts off its phosphatase activity under acidic conditions...
December 13, 2017: Nature Communications
https://www.readbyqxmd.com/read/29229443/immune-functions-of-insect-%C3%AE-grps-and-their-potential-application
#17
Xiang-Jun Rao, Ming-Yue Zhan, Yue-Min Pan, Su Liu, Pei-Jin Yang, Li-Ling Yang, Xiao-Qiang Yu
Insects rely completely on the innate immune system to sense the foreign bodies and to mount the immune responses. Germ-line encoded pattern recognition receptors play crucial roles in recognizing pathogen-associated molecular patterns. Among them, β-1,3-glucan recognition proteins (βGRPs) and gram-negative bacteria-binding proteins (GNBPs) belong to the same pattern recognition receptor family, which can recognize β-1,3-glucans. Typical insect βGRPs are comprised of a tandem carbohydrate-binding module in the N-terminal and a glucanase-like domain in the C-terminal...
December 8, 2017: Developmental and Comparative Immunology
https://www.readbyqxmd.com/read/29224584/long-term-implications-of-feed-energy-source-in-different-genetic-types-of-reproductive-rabbit-females-iii-fitness-and-productivity
#18
A Arnau-Bonachera, D Savietto, J J Pascual
The specialization process associated with genetic selection could be associated with functional disorders, affecting the reproductive success of females (fitness). We hypothesized that by modulating energy acquisition and allocation of females we could balance productivity and reproductive success. To test this hypothesis, we used 203 rabbit females belonging to three genetic types: H (n=66) maternal line specialized in prolificacy, LP (n=67) generalist maternal line, R (n=70) paternal line specialized in growth rate...
December 11, 2017: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/29219246/identification-and-genomic-characterization-of-the-emerging-senecavirus-a-in-southeast-china-2017
#19
X Zhang, J Xiao, L Ba, F Wang, D Gao, J Zhang, C Pan, P Qi
Senecavirus A (SVA) is an emerging non-enveloped virus with a single-stranded, positive-sense RNA genome that belongs to the Senecavirus genus in the Picornaviridae family. Senecavirus A-associated swine idiopathic vesicular disease and epidemic transient neonatal losses have caused substantial economic losses for the swine industry. Here, we describe a case of re-emerging vesicular disease among sows and finishing pigs on a swine farm in Fujian Province of southeast China. Other causative pathogens, including FMDV, SVDV and VSV, were excluded, and a novel SVA strain, CH-FJZZ-2017, was isolated...
December 8, 2017: Transboundary and Emerging Diseases
https://www.readbyqxmd.com/read/29216874/factors-influencing-the-experience-of-sexual-and-reproductive-healthcare-for-female-adolescents-with-perinatally-acquired-hiv-a-qualitative-case-study
#20
Gertrude Mwalabu, Catrin Evans, Sarah Redsell
BACKGROUND: Young people living with perinatally-acquired HIV require age-appropriate support regarding sex and relationships as they progress towards adulthood. HIV affects both genders but evidence suggests that young women are particularly vulnerable to sexual abuse and more prone to engaging in sexual behaviours to meet their daily survival needs. This can result in poor sexual and reproductive health (SRH) outcomes. HIV services in Malawi provide support for young women's HIV-related clinical needs, but it is unclear whether there is sufficient provision for their SRH needs as they become adults...
December 8, 2017: BMC Women's Health
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