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https://www.readbyqxmd.com/read/28345965/experiences-of-attending-day-care-services-designed-for-people-with-dementia-a-qualitative-study-with-individual-interviews
#1
Margit Gausdal Strandenæs, Anne Lund, Anne Marie Mork Rokstad
OBJECTIVES: Day care is assumed to promote independence in home-dwelling people with dementia, increase well-being and enhance social stimulation. Few studies have directly engaged people with dementia to better understand the benefits and impacts of such services. The aim of this study was to explore attendees' experiences with day care designed for people with dementia. METHOD: This study had a qualitative descriptive design and included individual interviews with 17 users attending day care...
March 27, 2017: Aging & Mental Health
https://www.readbyqxmd.com/read/28336824/-the-functions-of-calcium-sensing-receptor-in-regulating-mineral-metabolism
#2
Yuka Kinoshita
Calcium-sensing receptor(CaSR)which belongs to a G protein-coupled receptor family is one of the key elements in regulating calcium homeostasis. CaSR has been identified as a receptor to control parathyroid hormone(PTH)secretion in parathyroid glands according to serum calcium ion(Ca2+)levels. It has also been shown that CaSR controls reabsorption of water and several cations including Ca2+and magnesium ion(Mg2+)in renal tubular cells. This review summarizes the functions and roles of CaSR in mineral metabolism that are exerted in parathyroid glands, kidney, and intestine...
2017: Clinical Calcium
https://www.readbyqxmd.com/read/28328385/a-qualitative-study-exploring-women-s-journeys-to-becoming-smokers-in-the-social-context-of-urban-india
#3
Aarti Nagarkar, Devashri Salvi
In India, the prevalence of smoking among women is increasing, and the reasons behind this are unclear. We aimed to study the factors leading to initiation and maintenance of the smoking habit in women in Pune, India. Twenty-seven urban women-smokers, ranging from 21 to 60 years of age (31.96 ± 10.70 years), were interviewed from September 2015 to February 2016. The in-depth interviews consisted of questions on pre-decided categories, viz., initiation, motivation to continue smoking, and risk perception...
March 22, 2017: Women & Health
https://www.readbyqxmd.com/read/28298368/building-a-new-life-in-australia-an-analysis-of-the-first-wave-of-the-longitudinal-study-of-humanitarian-migrants-in-australia-to-assess-the-association-between-social-integration-and-self-rated-health
#4
Wen Chen, Li Ling, Andre M N Renzaho
OBJECTIVES: To assess the relationship between social integration and physical and mental health among humanitarian migrants (HMs) in Australia. DESIGN, SETTING AND PARTICIPANTS: We used the recently released first wave of data from the 2013 'Building a New Life in Australia' survey, which is an ongoing nationwide longitudinal study. A total of 2399 HMs participated in the survey. MAIN OUTCOME MEASURES: Self-rated physical health was measured using four items selected from the SF-36 which is a generic measure of health status...
March 15, 2017: BMJ Open
https://www.readbyqxmd.com/read/28292700/canonical-and-noncanonical-functions-of-ulk-atg1
#5
REVIEW
Bo Wang, Mondira Kundu
Mammalian Unc-51-like kinases 1 and 2 (ULK1 and ULK2) belong to the ULK/Atg1 family of serine/threonine kinases, which are conserved from yeast to mammals. Although ULK/Atg1 is best known for regulating flux through the autophagy pathway, it has evolutionarily conserved noncanonical functions in protein trafficking that are essential for maintaining cellular homeostasis. As a direct target of energy- and nutrient-sensing kinases, ULK/Atg1 is positioned to regulate the distribution and use of cellular resources in response to metabolic cues...
March 11, 2017: Current Opinion in Cell Biology
https://www.readbyqxmd.com/read/28276186/a-novel-highly-conserved-metallothionein-family-in-basidiomycete-fungi-and-characterization-of-two-representative-slmta-and-slmtb-genes-in-the-ectomycorrhizal-fungus-suillus-luteus
#6
Hoai Nguyen, François Rineau, Jaco Vangronsveld, Ann Cuypers, Jan V Colpaert, Joske Ruytinx
The basidiomycete Suillus luteus is an important member of the ectomycorrhizal community that thrives in heavy metal polluted soils covered with pioneer pine forests. This study aimed to identify potential heavy metal chelators in S. luteus. Two metallothionein (MT) coding genes, SlMTa and SlMTb, were identified. When heterologously expressed in yeast, both SlMTa and SlMTb can rescue the Cu sensitive mutant from Cu toxicity. In S. luteus, transcription of both SlMTa and SlMTb is induced by Cu but not Cd nor Zn...
March 9, 2017: Environmental Microbiology
https://www.readbyqxmd.com/read/28267410/combined-haplotypes-of-casr-gene-sequence-variants-and-their-associations-with-growth-traits-in-cattle
#7
Binglin Yue, Fuhai Han, Jiyao Wu, Yanhuan Wang, Chunlei Zhang, Xingtang Fang, Xinglei Qi, Yueyu Bai, Hong Chen
The calcium-sensing receptor (CaSR) is a Class C G-protein coupled receptor that regulates food intake and assimilation. However, studies on the relationship between CaSR gene and growth traits in cattle are deficient. The aim of this study was to examine the association of the CaSR polymorphism with growth traits in cattle breeds. Four novel single nucleotide polymorphisms (SNPs) and one previously reported SNP (NC_007299.5: g.67630865T>C, 67638409G>C, 67660395G>C, 67661546C>G, and 67661892A>C) were identified in the bovine CaSR gene using DNA sequencing and PCR-SSCP methods in 520 individuals from three representative breeds...
March 7, 2017: Animal Biotechnology
https://www.readbyqxmd.com/read/28251783/indole-signaling-and-micro-algal-auxins-decrease-the-virulence-of-vibrio-campbellii-a-major-pathogen-of-aquatic-organisms
#8
Qian Yang, Gde Sasmita Julyantoro Pande, Zheng Wang, Baochuan Lin, Robert A Rubin, Gary J Vora, Tom Defoirdt
Vibrios belonging to the Harveyi clade are major pathogens of marine vertebrates and invertebrates, causing major losses in wild and cultured organisms. Despite their significant impact, the pathogenicity mechanisms of these bacteria are not yet completely understood. In this study, we investigated the impact of indole signaling on the virulence of Vibrio campbellii. Elevated indole levels significantly decreased motility, biofilm formation, exopolysaccharide production and virulence to crustacean hosts. Indole furthermore inhibited the three-channel quorum sensing system of V...
March 2, 2017: Environmental Microbiology
https://www.readbyqxmd.com/read/28250336/the-periplasmic-sensing-domain-of-pseudomonas-fluorescens-chemotactic-transducer-of-amino-acids-type-b-ctab-cloning-refolding-purification-crystallization-and-x-ray-crystallographic-analysis
#9
Abu Iftiaf Md Salah Ud-Din, Anna Roujeinikova
Pseudomonas fluorescens is a plant growth promoting rhizobacterium that provides nutrients for growth and induces systemic resistance against plant diseases. It has been linked with a number of human diseases including nosocomial infections and bacterial cystitis. Chemotactic motility of P. fluorescens towards root exudates plays a crucial role in establishing a symbiotic relationship with host plants. The P. fluorescens chemotactic transducer of amino acids type B (CtaB) mediates chemotaxis towards amino acids...
February 28, 2017: Bioscience Trends
https://www.readbyqxmd.com/read/28242447/levofloxacin-capped-ag-nanoparicles-a-new-highly-selective-sensor-for-cations-under-joint-experimental-and-dft-investigation
#10
Sutapa Mondal Roy, Debesh Ranjan Roy
A very new and alternate function of an antibiotic drug levofloxacin (Lv), as a highly selective, colorimetric turn-OFF/turn-ON chemosensor for metal-ions Hg(2+) and Fe(3+), has been reported in this study. An extremely easy, very less time consuming, economical one-pot method of synthesis has been developed for the production of silver nanoparticles (AgNPs). The AgNPs that are stabilized and surface functionalized by Lv. Functionalization of AgNPs by antibiotic drug Lv has been thoroughly confirmed using FTIR spectrophotometry...
February 17, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28223788/the-level-of-emotion-control-anxiety-and-self-efficacy-in-the-elderly-in-bialystok-poland
#11
Mateusz Cybulski, Lukasz Cybulski, Elzbieta Krajewska-Kulak, Urszula Cwalina
PURPOSE: The aim of the study was to assess the level of emotion control, anxiety, and self-efficacy in the inhabitants of Bialystok (Poland) aged above 60. PATIENTS AND METHODS: The study included 300 people above the age of 60, inhabitants of Bialystok and its neighborhoods: 100 residents of public nursing home, 100 participants of the University of the Third Age in Bialystok, and 100 students of the University of Healthy Senior. The three standardized psychometric scales were used in the study: Courtauld Emotional Control Scale (CECS), State-Trait Anxiety Inventory (STAI), and General Self-Efficacy Scale (GSES)...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28220963/the-association-between-gender-ethnicity-and-suicidality-among-vocational-students-in-israel
#12
Joy Benatov, Ora Nakash, Shai Chen-Gal, Anat Brunstein Klomek
Gender and ethnicity are significant factors when evaluating suicidal risk, especially among ethnically diverse populations. In the current study we explored the association between gender, ethnicity, and suicide ideation and attempts among Arab and Jewish vocational education and training high school students in Israel. Students (N = 3,554) completed a self-report survey evaluating suicide ideation and attempts, depression, anxiety, somatization, and sense of belonging. Hierarchical generalized linear modeling indicated that female Arab adolescents had elevated levels of suicide ideation, higher rates of suicide attempts, and greater psychological distress than Arab males and Jewish students...
February 21, 2017: Suicide & Life-threatening Behavior
https://www.readbyqxmd.com/read/28208598/neighborhood-environment-and-falls-among-community-dwelling-older-adults
#13
Emily Joy Nicklett, Matthew C Lohman, Matthew Lee Smith
Background: Falls present a major challenge to active aging, but the relationship between neighborhood factors and falls is poorly understood. This study examined the relationship between fall events and neighborhood factors, including neighborhood social cohesion (sense of belonging, trust, friendliness, and helpfulness) and physical environment (vandalism/graffiti, rubbish, vacant/deserted houses, and perceived safety walking home at night). Methods: Data were analyzed from 9259 participants over four biennial waves (2006-2012) of the Health and Retirement Study (HRS), a nationally representative sample of adults aged 65 and older in the United States...
February 10, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28193786/bile-acids-potentiate-proton-activated-currents-in-xenopus-laevis-oocytes-expressing-human-acid-sensing-ion-channel-asic1a
#14
Alexandr V Ilyaskin, Alexei Diakov, Christoph Korbmacher, Silke Haerteis
Acid-sensing ion channels (ASICs) are nonvoltage-gated sodium channels transiently activated by extracellular protons and belong to the epithelial sodium channel (ENaC)/Degenerin (DEG) family of ion channels. Bile acids have been shown to activate two members of this family, the bile acid-sensitive ion channel (BASIC) and ENaC. To investigate whether bile acids also modulate ASIC function, human ASIC1a was heterologously expressed in Xenopus laevis oocytes. Exposing oocytes to tauro-conjugated cholic (t-CA), deoxycholic (t-DCA), and chenodeoxycholic (t-CDCA) acid at pH 7...
February 2017: Physiological Reports
https://www.readbyqxmd.com/read/28190937/belonging-and-unbelonging-jewish-refugee-and-survivor-women-in-1950s-britain
#15
Angela Davis
This article analyses the life stories of female Jewish refugees and survivors in 1950s Britain in order to explore their relationship with the existing Jewish community and wider society. The paper is based on an analysis of twenty-one oral history testimonies from the Jewish survivors of the Holocaust collection held at the British library. Around 50,000 Jewish refugees from Central Europe came to Britain in the 1930s after fleeing from Hitler. In addition, a relatively small number of camp survivors and former hidden children settled in the country after the war; the Board of Deputies of British Jews Demographic Unit estimates the figure at 2000...
January 2, 2017: Women's History Review
https://www.readbyqxmd.com/read/28181795/water-responsive-shape-recovery-induced-buckling-in-biodegradable-photo-cross-linked-poly-ethylene-glycol-peg-hydrogel
#16
Abhijit Vijay Salvekar, Wei Min Huang, Rui Xiao, Yee Shan Wong, Subbu S Venkatraman, Kiang Hiong Tay, Ze Xiang Shen
The phenomenon of recovering the permanent shape from a severely deformed temporary shape, but only in the presence of the right stimulus, is known as the shape memory effect (SME). Materials with such an interesting effect are known as shape memory materials (SMMs). Typical stimuli to trigger shape recovery include temperature (heating or cooling), chemical (including water/moisture and pH value), and light. As a SMM is able not only to maintain the temporary shape but also to respond to the right stimulus when it is applied, via shape-shifting, a seamless integration of sensing and actuation functions is achieved within one single piece of material...
February 9, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/28177307/acedrg-a-stereochemical-description-generator-for-ligands
#17
Fei Long, Robert A Nicholls, Paul Emsley, Saulius Graǽulis, Andrius Merkys, Antanas Vaitkus, Garib N Murshudov
The program AceDRG is designed for the derivation of stereochemical information about small molecules. It uses local chemical and topological environment-based atom typing to derive and organize bond lengths and angles from a small-molecule database: the Crystallography Open Database (COD). Information about the hybridization states of atoms, whether they belong to small rings (up to seven-membered rings), ring aromaticity and nearest-neighbour information is encoded in the atom types. All atoms from the COD have been classified according to the generated atom types...
February 1, 2017: Acta Crystallographica. Section D, Structural Biology
https://www.readbyqxmd.com/read/28170406/youth-as-contested-sites-of-culture-the-intergenerational-acculturation-gap-amongst-new-migrant-communities-parental-and-young-adult-perspectives
#18
Andre M N Renzaho, Nidhi Dhingra, Nichole Georgeou
BACKGROUND: Immigration often results in changes in family dynamics, and within this process of dynamic relational adjustment youth can be conceptualised as contested sites of culture and associated intergenerational conflicts. This paper considers the experiences of migrant youth in Greater Western Sydney, New South Wales, Australia using conflict as a useful lens through which to view issues of migrant youth identity and their sense of social connectedness, belonging, and agency. The aim of this study was twofold: 1) to explore how migrant youth cope with acculturative stress and intergenerational conflicts, and 2) to better understand the systemic and family-related factors that facilitate positive settlement experiences for migrant youth...
2017: PloS One
https://www.readbyqxmd.com/read/28124783/diversity-of-culturable-bacterial-communities-in-the-intestinal-tracts-of-goldfish-carassius-auratus-and-their-ability-to-produce-n-acyl-homoserine-lactone
#19
Haruo Sugita, Shun Kitao, Satoshi Narisawa, Ryosuke Minamishima, Shiro Itoi
Intestinal bacteria isolated from goldfish (Carassius auratus) were identified based on 16 ribosomal RNA (rRNA) gene sequences and screened for their ability to produce N-acyl homoserine lactone (AHL), an autoinducer of the quorum sensing (QS) system. The 230 aerobes/facultative anaerobes that were isolated comprised members of the genera Aeromonas (184 isolates), Citrobacter (11), Enterobacter (2), Shewanella (28), Vagococcus (1), and Vibrio (4). Among these genera, the two most abundant species were Aeromonas veronii (163 isolates) and Shewanella xiamenensis (27)...
January 26, 2017: Folia Microbiologica
https://www.readbyqxmd.com/read/28124211/youth-from-fundamentalist-societies-what-are-their-attitudes-toward-war-and-peace-and-their-relations-with-anxiety-reactions
#20
Tehila Kalagy, Orna Braun-Lewensohn, Sara Abu-Kaf
The present study was conducted during "Protective Edge," a long-lasting military operation between the State of Israel and Hamas in Gaza, during which hundreds of rockets were fired from Gaza into various regions across the country. At the same time, Israeli forces bombed Gaza and sent in ground forces. The military operation ended after 50 days of fighting, with a cease-fire between the warring sides. The aim of this study was to compare attitudes and perceptions of youth from different religious fundamentalist societies, toward the war and their readiness for peace during this specific violent struggle, and attitudes toward the Israeli-Palestinian (I-P) conflict in general...
June 2017: Journal of Religion and Health
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