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Online Wellness

Bryan W Heckman, K Michael Cummings, Georges J Nahas, Marc C Willemsen, Richard J O'Connor, Ron Borland, Alexander A Hirsch, Warren K Bickel, Matthew J Carpenter
Introduction: The demand for alternative nicotine/tobacco products is not well established. This paper uses a behavioral economic approach to test whether smokers have differential demand for conventional factory-made, electronic, and very low nicotine content cigarettes (FMCs/ECs/VLNCs) and uses the prospective cohort design to test the predictive validity of demand indices on subsequent use of commercially available FMCs and ECs. Methods: Daily smokers (>16 years) from the Netherlands completed an online survey in April 2014 (N=1215)...
March 14, 2018: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
Jiawei Wang, Bingjiao Yang, André Leier, Tatiana T Marquez-Lago, Morihiro Hayashida, Andrea Rocker, Zhang Yanju, Tatsuya Akutsu, Kuo-Chen Chou, Richard A Strugnell, Jiangning Song, Trevor Lithgow
Motivation: Many Gram-negative bacteria use type VI secretion systems (T6SS) to export effector proteins into adjacent target cells. These secreted effectors (T6SEs) play vital roles in the competitive survival in bacterial populations, as well as pathogenesis of bacteria. Although various computational analyses have been previously applied to identify effectors secreted by certain bacterial species, there is no universal method available to accurately predict T6SS effector proteins from the growing tide of bacterial genome sequence data...
March 14, 2018: Bioinformatics
David Kavaler, Vladimir Filkov
Stack Overflow is a popular crowdsourced question and answer website for programming-related issues. It is an invaluable resource for software developers; on average, questions posted there get answered in minutes to an hour. Questions about well established topics, e.g., the coercion operator in C++, or the difference between canonical and class names in Java, get asked often in one form or another, and answered very quickly. On the other hand, questions on previously unseen or niche topics take a while to get a good answer...
2018: PloS One
Sherry Hamby, Zach Blount, Alli Smith, Lisa Jones, Kimberly Mitchell, Elizabeth Taylor
Many forms of victimization, including bullying and property crime, are increasingly moving online, but most studies of poly-victimization still primarily focus on in-person crime and violence. Few studies have examined the importance of incorporating technology-based victimizations for assessing the true burden of violence. The purpose of this study is to explore whether digital poly-victimization contributes to post-traumatic stress and anxiety/dysphoria symptoms after controlling for in-person poly-victimization...
May 2018: Journal of Trauma & Dissociation
N Tehrani
Background: Working with victims and offenders of child abuse can impact on the health and well-being of police officers and staff. Aims: To identify the effects of tenure, work ability, gender and a personal experience of child abuse on symptoms of anxiety, depression and primary and secondary trauma in child abuse investigators (CAIs). Methods: Screening questionnaires were sent to police officers and staff. The officers and staff worked in child protection in seven police forces...
March 13, 2018: Occupational Medicine
Barbara J Howard, Raymond Sturner
Purpose of review: To describe benefits and problems with screening and addressing developmental and behavioral problems in primary care and using an online clinical process support system as a solution. Recent findings: Screening has been found to have various implementation barriers including time costs, accuracy, workflow and knowledge of tools. In addition, training of clinicians in dealing with identified issues is lacking. Patients disclose more to and prefer computerized screening...
December 2017: Current Developmental Disorders Reports
Agnes Leu, Corinna Jung, Marianne Frech, Joe Sempik, Urs Moser, Martin Verner, Saul Becker
BACKGROUND: In Switzerland, the issue of young carers and young adult carers - young people under the age of 18 and 24 respectively, who take on significant or substantial caring tasks and levels of responsibility that would usually be associated with an adult - has not been researched before. The number of these younger carers is unknown, as is the extent and kind of their caring activities and the outcomes for their health, well-being, psycho-social development, education, transitions to adulthood, future employability and economic participation...
March 15, 2018: BMC Health Services Research
Emily K Prentiss, Colleen L Schneider, Zoë R Williams, Bogachan Sahin, Bradford Z Mahon
The division of labour between the dorsal and ventral visual pathways is well established. The ventral stream supports object identification, while the dorsal stream supports online processing of visual information in the service of visually guided actions. Here, we report a case of an individual with a right inferior quadrantanopia who exhibited accurate spontaneous rotation of his wrist when grasping a target object in his blind visual field. His accurate wrist orientation was observed despite the fact that he exhibited no sensitivity to the orientation of the handle in a perceptual matching task...
March 15, 2018: Cognitive Neuropsychology
Patricia C Griffiths, Mariya Kovaleva, Melinda Higgins, Ashley H Langston, Kenneth Hepburn
INTRODUCTION: This study examined the feasibility and efficacy of Tele-Savvy, an online version of the Savvy Caregiver Program, a psychoeducation program for caregivers caring for a person with dementia. METHODS: A convenience sample of 22 caregivers from the Atlanta VA and 42 caregivers from 14 different states enrolled in Tele-Savvy. Pre- and post-program evaluations assessed caregiver burden, caregiver competency, and frequency of behavioral and psychological symptoms of dementia (BPSD)...
January 1, 2018: American Journal of Alzheimer's Disease and Other Dementias
Tongyang Li, Shaoping Wang, Enrico Zio, Jian Shi, Wei Hong
Leakage is the most important failure mode in aircraft hydraulic systems caused by wear and tear between friction pairs of components. The accurate detection of abrasive debris can reveal the wear condition and predict a system's lifespan. The radial magnetic field (RMF)-based debris detection method provides an online solution for monitoring the wear condition intuitively, which potentially enables a more accurate diagnosis and prognosis on the aviation hydraulic system's ongoing failures. To address the serious mixing of pipe abrasive debris, this paper focuses on the superimposed abrasive debris separation of an RMF abrasive sensor based on the degenerate unmixing estimation technique...
March 15, 2018: Sensors
Marc N Jarczok, Corina Aguilar-Raab, Julian Koenig, Michael Kaess, Jeremy C Borniger, Randy J Nelson, Martica Hall, Beate Ditzen, Julian F Thayer, Joachim E Fischer
INTRODUCTION: Successful regulation of emotional states is positively associated to mental health, while difficulties in regulating emotions are negatively associated to overall mental health and in particular associated with anxiety or depression symptoms. A key structure associated to socio-emotional regulatory processes is the central autonomic network. Activity in this structure is associated to vagal activity can be indexed noninvasively and simply by measures of peripheral cardiac autonomic modulations such as heart rate variability...
March 15, 2018: Chronobiology International
Gernot Kriegshäuser, Dietmar Enko, Hasmik Hayrapetyan, Stepan Atoyan, Christian Oberkanins, Tamara Sarkisian
PurposeThis work aimed at investigating demographic, clinical, and genetic characteristics of individuals experiencing their first familial Mediterranean fever (FMF) attack at age ≥40 years in a very large cohort of Armenian FMF patients.MethodsIn total, 10,370 Armenian patients diagnosed with FMF based on the Tel Hashomer criteria and carrying at least one MEFV mutant allele were included in this study.ResultsA total of 354 (3.40%) patients had late-onset FMF. Of these, 194 (54.80%) were female and 160 (45...
March 15, 2018: Genetics in Medicine: Official Journal of the American College of Medical Genetics
Lilian Roos, Wolfgang Taube, Carolin Tuch, Klaus Michael Frei, Thomas Wyss
PURPOSE: Session rating of perceived exertion (sRPE) is an often used measure to assess athletes' training load. However, little is known which factors could optimize the quality of data collection thereof. The aim of the present study was to investigate the effects of (i) the survey methods and (ii) the time points when sRPE was assessed on the correlation between subjective (sRPE) and objective (heart rate training impulse; TRIMP) assessment of training load. METHODS: In the first part, 45 well-trained subjects (30 men, 15 women) performed 20 running sessions with a heart rate monitor and reported sRPE 30 minutes after training cessation...
March 15, 2018: International Journal of Sports Physiology and Performance
Erin M Buchanan, John E Scofield
Web-based data collection methods such as Amazon's Mechanical Turk (AMT) are an appealing option to recruit participants quickly and cheaply for psychological research. While concerns regarding data quality have emerged with AMT, several studies have exhibited that data collected via AMT are as reliable as traditional college samples and are often more diverse and representative of noncollege populations. The development of methods to screen for low quality data, however, has been less explored. Omitting participants based on simple screening methods in isolation, such as response time or attention checks may not be adequate identification methods, with an inability to delineate between high or low effort participants...
March 14, 2018: Behavior Research Methods
Dieter Galea, Ivan Laponogov, Kirill Veselkov
Motivation: Recognition of biomedical entities from scientific text is a critical component of natural language processing and automated information extraction platforms. Modern named entity recognition approaches rely heavily on supervised machine learning techniques, which are critically dependent on annotated training corpora. These approaches have been shown to perform well when trained and tested on the same source. However, in such scenario, the performance and evaluation of these models may be optimistic, as such models may not necessarily generalize to independent corpora, resulting in potential non-optimal entity recognition for large-scale tagging of widely diverse articles in databases such as PubMed...
March 10, 2018: Bioinformatics
Joaquin Escribano, Natalia Ferré, Mariona Gispert-Llaurado, Veronica Luque, Carmen Rubio-Torrents, Marta Zaragoza-Jordana, Isabel Polanco, Francisco M Codoñer, Empar Chenoll, Mireia Morera, Jose Antonio Moreno Muñoz, Montserrat Rivero, Ricardo Closa-Monasterolo
BACKGROUND: Intestinal microbiota of breast-fed infants is plenty of beneficial bifidobacteria. We aimed to determine whether an infant formula supplemented with probiotic Bifidobacterium longum subsp. infantis CECT7210 (B. infantis IM1®) is effective at reducing diarrhoea incidence in healthy term infants. METHODS: Double-blinded, randomized, multicentre, controlled clinical trial, where formula-fed infants (<3 months) received an infant formula supplemented (Probiotic) or not (Control) with 107 cfu/g of B...
March 14, 2018: Pediatric Research
Bernadette O Erokwu, Christian E Anderson, Chris A Flask, Katherine M Dell
BACKGROUND: Autosomal Recessive Polycystic Kidney Disease (ARPKD) is associated with significant mortality and morbidity and there are currently no disease-specific treatments available for ARPKD patients. One major limitation in establishing new therapies for ARPKD is a lack of sensitive measures of kidney disease progression. Magnetic Resonance Imaging (MRI) can provide multiple quantitative assessments of disease. METHODS: We applied quantitative image analysis of high resolution (non-contrast) T2-weighted MRI techniques to study cystic kidney disease progression and response to therapy in the PCK rat model of ARPKD...
March 14, 2018: Pediatric Research
Carolyn J Baglole, Feng Liang, Hussein Traboulsi, Angela Rico de Souza, Christian Giordano, Josephine T Tauer, Frank Rauch, Basil J Petrof
BACKGROUND: Osteogenesis imperfecta (OI) is most often caused by mutations in type I collagen genes. Respiratory complications have been largely attributed to spine and ribcage deformities. We hypothesized that direct involvement of the pulmonary parenchyma and/or diaphragm by the disease may occur. METHODS: In Col1a1Jrt/+ mice, a model of severe dominant OI, mean linear intercept length (Lm) was used to assess distal airspace size. Cross-sectional area (CSA) and myosin heavy chain (MyHC) phenotype of diaphragm muscle fibers, as well as contractile properties, were determined...
March 14, 2018: Pediatric Research
Bridget M Smith, Rachael N Martinez, Charlesnika T Evans, Karen L Saban, Salva Balbale, Eric J Proescher, Kevin Stroupe, Timothy P Hogan
BACKGROUND: Veterans who experience traumatic brain injury (TBI) may have long-term needs placing a premium on well-coordinated care. This study aimed to (1) identify barriers to care coordination for Veterans with TBI; and (2) describe strategies used by VA polytrauma care team members to coordinate care for Veterans with TBI. METHODS: We utilised a mixed method design, including an online survey of VA polytrauma care team members (N = 236) and subsequent semi-structured interviews (N = 25)...
March 14, 2018: Brain Injury: [BI]
William R Phillips, Toby Keys
BACKGROUND AND OBJECTIVES: Primary care (PC) requires interprofessional teamwork and training. Although clinical training in PC settings is well developed in some professions, classroom teaching on the principles and practice of PC provides additional opportunities for interprofessional education. METHODS: We offered an elective one-credit classroom course on PC over 3 years, 2013 through 2015, enrolling students from dentistry, medicine, nursing, pharmacy, physician assistant, public health, social work, and other fields...
March 2018: Family Medicine
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