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Sacral neuromodulation

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https://www.readbyqxmd.com/read/29329897/-botulinium-toxin-and-idiopathic-overactive-bladder-multicentric-contempory-management-in-bourgogne
#1
A Schneider, B Tourlonias, L Cormier, E Mourey, N Koutlidis, E Delorme, J Pasquale, I Kermarec, A-D Foahom-Kamwa, V Bonniaud
INTRODUCTION: Since 2014, OnabotulinumtoxinA Botox® (Allergan, Inc., Irvine, USA) represents a new therapeutic option for second-line treatment of idiopathic overactive bladder. The purpose of the current study was to evaluate practices of surgeons using onabotulinium toxin (BoNTA) in this indication. MATERIAL AND METHODS: All urogynecology centers of the country were asked in order to list all patients who were treated since marketing autorisation. Patient symptoms, previous treatments, paraclinic evaluations, data of surgery and the characteristics of the follow up were collected and analyzed...
January 9, 2018: Progrès en Urologie
https://www.readbyqxmd.com/read/29320672/position-statement-a-clinical-approach-to-the-management-of-adult-non-neurogenic-overactive-bladder
#2
Eric Chung, Dominic Lee, Johan Gani, Michael Gillman, Christopher Maher, Janelle Brennan, Lydia Johns Putra, Laura Ahmad, Lewis Lw Chan
Overactive bladder (OAB) is a highly prevalent medical condition that has an adverse impact on various health-related quality-of-life domains, including a significant psychosocial and financial burden. This position statement, formulated by members of the Urological Society of Australia and New Zealand and the UroGynaecological Society of Australasia, summarises the current recommendations for clinical diagnosis and treatment strategies in patients with non-neurogenic OAB, and guides clinicians in the decision-making process for managing the condition using evidence-based medicine...
January 15, 2018: Medical Journal of Australia
https://www.readbyqxmd.com/read/29315785/three-month-clinical-results-with-a-rechargeable-sacral-neuromodulation-system-for-the-treatment-of-overactive-bladder
#3
Bertil Blok, Philip Van Kerrebroeck, Stefan de Wachter, Alain Ruffion, Frank Van der Aa, Ranjana Jairam, Marie Perrouin-Verbe, Sohier Elneil
AIMS: The primary aim of the RELAX-OAB study is to confirm the safety and efficacy of the Axonics r-SNM System, a miniaturized, rechargeable SNM system. METHODS: A total of 51 OAB patients were implanted in a single-stage implant procedure. These results represent the 3-month outcomes. Subject outcomes were evaluated using 3-day bladder diaries and quality of life questionnaires. RESULTS: A total of 31 of 34 patients (91%) that responded during an initial trial period ("Test Responders") continued to benefit from therapy with the Axonics r-SNM System at 3-months, defined as symptom improvement of ≥50% reduction in urinary voids or incontinence episodes or a return to <8 voids per day...
January 5, 2018: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/29302716/role-of-sacral-neuromodulation-in-modern-urogynaecology-practice-a-review-of-recent-literature
#4
REVIEW
Samina Tahseen
Sacral neuromodulation (SNM) offers promise in the therapy of many pelvic floor disorders. This innovative treatment has slowly gained popularity. A review of recent literature is presented in relation to its efficacy and complications in various pelvic floor conditions: overactive bladder and urge urinary incontinence, chronic urinary retention, painful bladder syndrome, pelvic pain and double incontinence. It is a minimally invasive, completely reversible safe procedure with good long-term outcomes. However, the treatment is costly, the revision rate is high and patients require life-long follow-up...
January 4, 2018: International Urogynecology Journal
https://www.readbyqxmd.com/read/29298468/radiographic-position-of-the-electrode-as-a-predictor-of-the-outcome-of-interstim-therapy
#5
Abdullah Ahmed Gahzi, Mai Ahmed Banakhar, Dean S Elterman, Magdy Hassouna
PURPOSE: Sacral neuromodulation (SNM) therapy is indicated for some refractory urological conditions. The electrode lead position in sacral x-rays during routine follow-up may predict the outcome of SNM therapy. To determine whether the radiographic position of the electrode in the sacral foramen predicted the long-term outcome of SNM therapy. METHODS: This was a retrospective study of patients who underwent InterStim SNM at Toronto Western Hospital by 2 surgeons from July 2013 to March 2014...
December 2017: International Neurourology Journal
https://www.readbyqxmd.com/read/29291416/onset-of-action-of-sacral-neuromodulation-in-lower-urinary-tract-dysfunction-what-is-the-optimal-duration-of-test-stimulation
#6
R Jairam, J Drossaerts, T Marcelissen, G van Koeveringe, Ph Van Kerrebroeck
PURPOSE: Since the development of sacral neuromodulation (SNM) a large number of patients with lower urinary tract symptoms (LUTS) have been treated with SNM. A test stimulation is performed prior to implantation. In centres worldwide the duration of this test stimulation varies considerably since it is not certain when the onset of the therapy effect can be expected. The objective of this prospective study is to evaluate the average onset time of SNM in patients with LUTS. METHODS: All patients who were eligible for treatment with SNM were asked to participate...
December 29, 2017: Journal of Urology
https://www.readbyqxmd.com/read/29280114/-promotion-of-basic-research-in-efficacy-enhancement-of-chronic-constipation
#7
Li Wang, Weidong Tong
The incidence of chronic constipation increases year by year, but it is underestimated in affecting the health of patients. Clinical diagnosis and treatment of chronic intractable constipation is difficult, owing to the diversity of clinical manifestations and the unclear pathogenesis. The basic research is expected to identify the pathophysiological mechanism of chronic intractable constipation in the future, which can find out a ultimate solution approach and improve clinical efficacy. At present there are several basic research ways attracting our attention, including enteric nervous system (such as nerve cells, intestinal neurotransmitters, intestinal sensory nerve regulation mechanism), intestinal smooth muscle cells, Cajal interstitial cells and sacral neuromodulation and intestinal microecology...
December 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29279881/current-pharmacological-and-surgical-treatment-of-underactive-bladder
#8
REVIEW
Dae Kyung Kim
Generally accepted guidelines are not yet available on the management of underactive bladder (UAB). Although the natural history of UAB is still not fully understood, observation may be an acceptable management option in patients with tolerable lower urinary tract symptoms and little risk of upper urinary tract damage. If needed, scheduled and double voiding may be recommended as an effective and safe add-on therapy. Parasympathomimetics have been widely used for the management of UAB, but the evidence does not support clinical benefit...
December 2017: Investigative and Clinical Urology
https://www.readbyqxmd.com/read/29218704/sacral-neuromodulation-for-pelvic-pain-and-pelvic-organ-dysfunction-a-case-series
#9
Thierry Vancaillie, Lauren Kite, Elizabeth Howard, Jason Chow
BACKGROUND: The use of neuromodulation is growing and it is an established therapy for conditions such as bladder dysfunction. It is an increasingly used therapy for the management of chronic perineal pain but little research is currently available looking at its efficacy. AIM: We present a series of 52 patients who underwent placement of a neuromodulator, the majority of whom suffered from perineal pain, with most placements via the sacral hiatus. METHOD: Patients were asked to complete a survey recalling their symptoms prior to implantation and describing their symptoms and experience after...
December 8, 2017: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/29160571/sacral-neuromodulation-and-pregnancy-results-of-a-national-survey-carried-out-for-the-neuro-urology-committee-of-the-french-association-of-urology-afu
#10
Pauline Roulette, Evelyne Castel-Lacanal, Sylvain Sanson, Romain Caremel, Véronique Phé, Stéphane Bart, Franck Duchêne, Marianne De Sèze, Alexia Even, Andréa Manunta, Maria C Scheiber-Nogueira, Pascal Mouracade, Catherine-Marie Loche, Emmanuel Chartier-Kastler, Alain Ruffion, Gilles Karsenty, Xavier Gamé
AIMS: To assess the impact of sacral neuromodulation (SNM) on pregnancy and vice-versa, by identifying women who had received SNM for lower-urinary tract symptoms (LUTS) and had become pregnant. METHODS: A cross-sectional descriptive study was carried out based on responses to an on-line questionnaire sent to practitioners listed on the InterStim enCaptureTM National Registry. Questions were related to pre-pregnancy health and SNM efficacy, deactivation of the device, its impact on LUTS, childbirth, the infant, its reactivation and postpartum effectiveness...
November 21, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/29154850/motor-response-matters-optimizing-lead-placement-improves-sacral-neuromodulation-outcomes
#11
Javier Pizarro-Berdichevsky, Bradley C Gill, Marisa Clifton, Henry T Okafor, Anna E Faris, Sandip P Vasavada, Howard B Goldman
PURPOSE: To determine the utility of motor responses during Sacral Neuromodulation (SNM) lead placement by testing the hypothesis that a greater number of motor responses during intraoperative electrode testing is associated with more durable therapy. MATERIALS AND METHODS: A retrospective review of all SNM lead placements at a large academic center from 2010-2015 was performed. All unilateral sacral lead placements with the presence or absence of a motor response documented discretely for each electrode were included...
November 14, 2017: Journal of Urology
https://www.readbyqxmd.com/read/29133935/sacral-neuromodulation-and-alterations-in-brain-activity-discussing-discrepancies
#12
Bradley C Gill, Howard B Goldman
No abstract text is available yet for this article.
November 14, 2017: Nature Reviews. Urology
https://www.readbyqxmd.com/read/29115915/neuromodulation-in-multiple-sclerosis
#13
Hesham Abboud, Eddie Hill, Junaid Siddiqui, Alessandro Serra, Benjamin Walter
Neuromodulation, or the utilization of advanced technology for targeted electrical or chemical neuronal stimulation or inhibition, has been expanding in several neurological subspecialties. In the past decades, immune-modulating therapy has been the main focus of multiple sclerosis (MS) research with little attention to neuromodulation. However, with the recent advances in disease-modifying therapies, it is time to shift the focus of MS research to neuromodulation and restoration of function as with other neurological subspecialties...
November 2017: Multiple Sclerosis: Clinical and Laboratory Research
https://www.readbyqxmd.com/read/29110390/a-novel-three-dimensional-printed-guiding-device-for-electrode-implantation-of-sacral-neuromodulation
#14
Zhe Cui, Zheng Wang, Guangyao Ye, Cheng Zhang, Guangyu Wu, Jianwei Lv
OBJECTIVE: To test the feasibility of a novel three-dimensional (3D) printed guiding device for electrode implantation of sacral neuromodulation (SNM). METHOD: A 3D printed guiding device for electrode implantation was customized as patients' anatomy of sacral region. Liquid photopolymer was selected as printing material. The details of device designation and prototype building are described. The guiding device was used in two patients underwent SNM for intractable constipation...
November 7, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/29102296/sacral-neuromodulation-for-faecal-incontinence-10-years-experience-at-a-scottish-tertiary-centre
#15
Hoey Koh, Stephen McSorley, Sarah Hunt, Martha Quinn, Graham MacKay, John Anderson
INTRODUCTION: Sacral nerve stimulation (SNS) is increasingly popular in the management of faecal incontinence. This paper reports the first 10-year experience of SNS in the management of faecal incontinence at a tertiary referral centre. Data was collected in a prospectively maintained database. RESULTS: In total 130 patients were referred. The majority were women (94%) under 75-year-old (98%). Seven patients were found to have full-thickness rectal prolapse at the initial work-up and proceeded to rectopexy...
October 25, 2017: Surgeon: Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland
https://www.readbyqxmd.com/read/29083137/efficacy-and-acceptance-of-the-sacral-neuromodulation-in-the-treatment-of-female-lower-urinary-tract-dysfunctions
#16
Biagio Adile, Patrizia Speciale, Giorgio Gugliotta, Paola Consiglio, Maria Manzone, Giorgio Adile, Salvatore Saitta, Antonino Perino, Gloria Calagna
No abstract text is available yet for this article.
October 27, 2017: Minerva Ginecologica
https://www.readbyqxmd.com/read/29072045/intradetrusor-injection-of-botulinum-toxin-a-and-sacral-neuromodulation-for-neurogenic-detrusor-overactivity
#17
Charles Joussain, Veronique Phé, Alexia Even, Emmanuel Chartier Kastler, Pierre Denys
Intradetrusor injection of botulinum toxin A and sacral neuromodulation are the two recommended third line treatments for patients with neurogenic detrusor overactivity, before undergoing with surgery. However, only Botox® injection is supported by a high level of evidence allowing its recommendation by all institutional guidelines. Despite few positive results, sacral neuromodulation should be proposed in carefully selected patients. Indeed, other studies remain mandatory to increase its level of evidence necessary for allowing its use in neurogenic detrusor overactivity (NDO)...
October 25, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/29065235/comparison-of-active-stimulating-electrodes-of-sacral-neuromodulation
#18
Xin Su, Matthew Cutinella, Jason E Agran, David A Dinsmoor
OBJECTIVE: The goal of this study was to compare the motor response to sacral neuromodulation (SNM) with different pairs of stimulating electrodes in anesthetized and awake sheep. MATERIALS AND METHODS: Similar to SNM clinical use in humans, the InterStim(®) quadripolar tined lead was implanted adjacent to the S3 nerve root in sheep and bipolar stimulation was configured with one electrode negative and one electrode positive on the four contacts (0 most distal to device, 1, 2, and 3 most proximal)...
October 24, 2017: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/29063170/-neuromodulation-of-lower-urinary-tract-dysfunction
#19
REVIEW
T M Kessler, S de Wachter
Neuromodulative procedures such as transcutaneous electrical nerve stimulation (TENS), transcutaneous/percutaneous tibial nerve stimulation (TTNS/PTNS), and sacral neuromodulation (SNM) are promising second-line treatments for refractory lower urinary tract dysfunction. Using these therapies, both storage and voiding disorders but also bowel dysfunction might be successfully treated. Although the mechanism of action of neuromodulation is not well understood, it seems to involve modulation of spinal cord reflexes and brain networks by peripheral afferents (genital/rectal, tibial and sacral afferents in the case of TENS, TTNS/PTNS, and SNM, respectively)...
October 23, 2017: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/29059782/re-cost-profiles-and-budget-impact-of-rechargeable-versus-non-rechargeable-sacral-neuromodulation-devices-in-the-treatment-of-overactive-bladder-syndrome
#20
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