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Sacral neuromodulation

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https://www.readbyqxmd.com/read/29773501/what-is-new-in-neuromodulation-for-overactive-bladder
#1
REVIEW
Manuela Tutolo, Enrico Ammirati, Frank Van der Aa
We reviewed the available studies on efficacy and safety of percutaneous tibial nerve stimulation (PTNS) and sacral nerve modulation (SNM) for overactive bladder (OAB) symptoms not responsive to conservative treatments. We limited our search to randomized trials, in English, with at least 20 adult patients, and 6 mo and 12 wk of follow-up for SNM and PTNS, respectively, published between January 1998 and December 2017. Therapeutic success ranges from 61% to 90% for SNM and from 54% to 79% for PTNS. Both techniques are effective and safe, with no life-threatening adverse effects...
May 14, 2018: European Urology Focus
https://www.readbyqxmd.com/read/29746857/women-undergoing-third-line-overactive-bladder-treatment-demonstrate-elevated-thermal-temporal-summation
#2
W Stuart Reynolds, Casey Kowalik, Joshua Cohn, Melissa Kaufman, Alan Wein, Roger Dmochowski, Stephen Bruehl
PURPOSE: To determine if women with overactive bladder (OAB) requiring 3rd line therapy demonstrate greater central sensitization, indexed by temporal summation to heat pain stimuli, than those with OAB. MATERIALS AND METHODS: We recruited 39 adult women with OAB from the Urology clinic who were planning to undergo interventional therapy for medication refractory OAB with either onabotulinumtoxinA bladder injection or sacral neuromodulation and 55 women with OAB, either newly seen in our Urology clinic or responding to advertisements for study participation...
May 7, 2018: Journal of Urology
https://www.readbyqxmd.com/read/29725872/review-of-economic-value-drivers-of-the-treatment-of-overactive-bladder
#3
REVIEW
Sonya J Snedecor
Overactive bladder (OAB) is a symptom-driven condition with economic burden estimated to be on the order of several hundred dollars or euros per patient in some North American and European countries. This work reviews recently published economic models to evaluate how health states are defined, what cost components are considered, and what utility values are used to estimate the cost effectiveness of OAB pharmacotherapies, botulinum toxin, or sacral neuromodulation. It was found that no clear standard exists for determining OAB health states, although most were defined by some measure of incontinence frequency...
May 4, 2018: PharmacoEconomics
https://www.readbyqxmd.com/read/29682720/-research-progress-of-sacral-neuromodulation-procedure-in-the-treatment-of-chronic-constipation-and-fecal-incontinence
#4
Chenxiang He, Shaoqing Liu, Shisen Li, Bo Zhang, Jianyong Zheng
Sacral neuromodulation(SNM) procedure has become a new therapy to treat chronic constipation and fecal incontinence. The surgical procedure is easy and safe. It has a small incision compared with traditional surgery and is mainly used in patients whose traditional treatment was unsuccessful. Chronic constipation is one of the most common digestive symptoms. The quality of life in patients with severe constipation has decreased greatly. Although the incidence of fecal incontinence in China is not as high as that of constipation, it also seriously affects the life of the patients, resulting in a decline in the quality of life...
2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29677906/re-prediction-of-sacral-neuromodulation-treatment-success-in-men-with-impaired-bladder-emptying-time-for-a-new-diagnostic-approach
#5
Alan J Wein
No abstract text is available yet for this article.
May 2018: Journal of Urology
https://www.readbyqxmd.com/read/29642366/re-detailed-analysis-of-adverse-events-and-surgical-interventions-in-a-large-prospective-trial-of-sacral-neuromodulation-therapy-for-overactive-bladder-patients
#6
https://www.readbyqxmd.com/read/29627882/an-animal-model-of-faecal-incontinence-and-sacral-neuromodulation
#7
James F X Jones
The pudendal nerves can be injured during traumatic vaginal childbirth and result in faecal incontinence. Some of these incontinent patients benefit from chronic sacral neuromodulation and the mechanism of action of this therapy has been a focus of many studies. In 2008, a rodent model of neuropathic faecal incontinence was introduced and subsequently validated through a series of investigations. This review summarizes the decade-long contribution of Professor Ronan O'Connell to the inception and application of this rodent model of faecal incontinence and sacral neuromodulation...
April 8, 2018: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/29623108/electrical-neuromodulation-in-the-management-of-lower-urinary-tract-dysfunction-evidence-experience-and-future-prospects
#8
REVIEW
Alejandro Abello, Anurag K Das
Lower urinary tract dysfunction (LUTD) is common and causes a spectrum of morbidity and decreased quality of life (QoL) for patients. LUTD can range from urinary retention to urge incontinence, and includes a variety of syndromes, with the most common and widely recognized being overactive bladder (OAB). The classic treatments of LUTD and OAB comprise different strategies including behavioral therapies, medications and minimally invasive or invasive surgical procedures. Generally, once patients have tried behavioral modifications and oral medical therapy, and have not experienced adequate relief of their symptoms, the next step is to consider minimally invasive therapies...
May 2018: Therapeutic Advances in Urology
https://www.readbyqxmd.com/read/29593988/fowler-s-syndrome-post-oocyte-retrieval-for-intracytoplasmic-sperm-injection
#9
Gamar Salim, Mohammed Agdi, Jawharah Al-Zebeidi, Ashraf Dawood, Dania Al-Jaroudi
Objective: To report a case of Fowler's syndrome after oocyte retrieval. Design: Case report. Setting: Tertiary referral center, King Fahad Medical City. Patients: A 23-year-old nulligravida with polycystic ovarian syndrome and primary infertility underwent oocyte retrieval for intracytoplasmic sperm injection (ICSI), and developed Fowler's syndrome (FS). Interventions: Intermittent self-catheterization, insertion of sacral neuromodulator (SNM)...
April 2017: Case Reports in Women's Health
https://www.readbyqxmd.com/read/29574121/sacral-neuromodulation-and-twiddler-s-syndrome
#10
Ted M Roth
Twiddler's syndrome is the deliberate, inadvertent, or subconscious manipulation of an implantable generator within its subcutaneous pocket which can lead to malposition and fracture of the associated lead.1 The syndrome is well-recognized in patients with pacemakers, implantable cardioverter-defibrillators, deep brain stimulators and more recently in intrathecal drug delivery devices.1-3 Here we present an instance of Twiddler's syndrome after sacral neuromodulation [SNM].
March 21, 2018: Urology
https://www.readbyqxmd.com/read/29570127/successful-treatment-of-paradoxical-puborectalis-contraction-and-intractable-anorectal-pain-with-sacral-neuromodulation
#11
Ted M Roth
BACKGROUND: Paradoxical puborectalis contraction (PPC) is a syndrome of obstructed defecation associated with a cluster of complaints including rectal pain, incomplete evacuatory sensation, prolonged repetitive straining with bowel movements, and the need for digital manipulation. Traditional treatment has yielded mixed results. CASE: We present a case of PPC successfully treated with staged sacral neuromodulation and review her diagnostic features, medical regimen, and prior unsuccessful interventions tried...
March 21, 2018: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/29568364/efficacy-of-different-spinal-nerve-roots-for-neuromodulation-of-micturition-reflex-in-rats
#12
Jianshu Ni, Xiaohu Wang, Nailong Cao, Jiemin Si, Baojun Gu
Electrical stimulation of peripheral nerves controlling the bladder is an alternative, nondestructive medical treatment for urinary incontinence and retention. In this study, we aimed to identify the most efficient sensory and motor spinal nerve roots involved in the micturition reflex. Unilateral L5-S2 dorsal and ventral roots were electrically stimulated, and bladder reflex contractions were recorded under isovolumetric conditions. Repeated stimulation of the L6 and S1 dorsal roots not only abolished bladder reflex contractions but also induced a poststimulation inhibitory effect, whereas repeated stimulation of the L5 and S2 dorsal roots had no effect...
March 2, 2018: Oncotarget
https://www.readbyqxmd.com/read/29551556/what-is-the-best-treatment-option-for-coexisting-pelvic-floor-dysfunctions
#13
Manuela Tutolo, Enrico Ammirati, Frank Van der Aa
Although both intravesical onabotulinumtoxinA injections and sacral neuromodulation could be offered in cases of bladder pain syndrome and overactive bladder syndrome, there is still no scientific agreement on the best option after failure of standard therapies.
December 2017: European Urology Focus
https://www.readbyqxmd.com/read/29508446/predicting-a-successful-outcome-in-sacral-neuromodulation-testing-are-urodynamic-parameters-prognostic
#14
Richard P Nobrega, Eskinder Solomon, Julie Jenks, Tamsin Greenwell, Jeremy Ockrim
AIMS: To assess whether the urodynamic parameters of mean voided volume, peak detrusor overactivity (DO) pressure, bladder compliance, capacity, and volume at first detrusor overactivity during filling cystometry can predict a successful outcome at first stage tined lead placement (FSTLP). METHODS: Ninty-nine consecutive patients with urodynamically proven idiopathic detrusor overactivity (IDO) refractory to medical treatment and opting for Sacral Nerve Stimulation (SNS), were assessed pre and post FSTLP...
March 2018: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/29504634/affective-symptoms-and-quality-of-life-in-patients-with-voiding-or-storage-dysfunction-results-before-and-after-sacral-neuromodulation-a-prospective-follow-up-study
#15
Ranjana Jairam, Jamie Drossaerts, Desiree Vrijens, Carsten Leue, Philip van Kerrebroeck, Gommert van Koeveringe
AIMS: Sacral neuromodulation (SNM) is an effective treatment for patients with overactive bladder syndrome (OAB) or non-obstructive urinary retention (NOR). These lower urinary tract symptoms (LUTS) are the result of a functional urological cause but often coincide with psychological and/or psychiatric factors. It has been stated that there is an association between LUTS, depression and anxiety disorders. With this study we will investigate whether affective symptoms and quality of life (QoL) improve after successful SNM...
March 5, 2018: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/29484231/the-role-of-the-neurometer-cpt-c-in-sacral-neuromodulation
#16
Abdullah Ahmed Ghazi, Malak Abuzgaya, Mai Banakhar, Magdy Hassouna
Objective: The aim of the current research project was to study the role of the Neurometer® as a tool to predict responders to sacral neuromodulation therapy (SNM). Material and methods: This was a prospective, open study in male and female patients, aged 18 and over with voiding dysfunction [non-obstructive retention and/or frequency/ urgency syndrome]. The first group underwent a screening test to evaluate percutaneous nerve functions (PNE) and to determine whether they are candidates for SNM with the InterStim® ...
January 2018: Turkish Journal of Urology
https://www.readbyqxmd.com/read/29482936/two-year-outcomes-of-sacral-neuromodulation-versus-onabotulinumtoxina-for-refractory-urgency-urinary-incontinence-a-randomized-trial
#17
Cindy L Amundsen, Yuko M Komesu, Christopher Chermansky, W Thomas Gregory, Deborah L Myers, Emily F Honeycutt, Sandip P Vasavada, John N Nguyen, Tracey S Wilson, Heidi S Harvie, Dennis Wallace
BACKGROUND: Urgency urinary incontinence (UUI) is a chronic condition for which sacral neuromodulation (SNM) (InterStim/Medtronic) and onabotulinumtoxinA (BTX) (BotoxA/Allergan) are utilized. These therapies have not been compared over extended time. OBJECTIVE: To compare UUI episodes (UUIE) over 24 mo following SNM or BTX. DESIGN, SETTING, AND PARTICIPANTS: Multicenter, open-label, randomized, extension trial (February 2012-July 2016) at nine US medical centers involving 386 women with ≥6 UUIE over 3 d inadequately managed by medications...
February 23, 2018: European Urology
https://www.readbyqxmd.com/read/29470731/sacral-neuromodulation-versus-personalized-conservative-treatment-in-patients-with-idiopathic-slow-transit-constipation-study-protocol-of-the-no-2-trial-a-multicenter-open-label-randomized-controlled-trial-and-cost-effectiveness-analysis
#18
S C M Heemskerk, A H Rotteveel, M A Benninga, C I M Baeten, A A M Masclee, J Melenhorst, S M J van Kuijk, C D Dirksen, S O Breukink
PURPOSE: The evidence regarding the (cost-)effectiveness of sacral neuromodulation (SNM) in patients with therapy-resistant idiopathic slow-transit constipation is of suboptimal quality. The Dutch Ministry of Health, Welfare and Sports has granted conditional reimbursement for SNM treatment. The objective is to assess the effectiveness, cost-effectiveness, and budget impact of SNM compared to personalized conservative treatment (PCT) in patients with idiopathic slow-transit constipation refractory to conservative treatment...
April 2018: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/29464748/prospective-randomized-study-evaluating-ultrasound-versus-fluoroscopy-guided-sacral-interstim%C3%A2-lead-placement-a-pilot-study
#19
Jaschar Shakuri-Rad, Arman Cicic, Jannah Thompson
OBJECTIVE: To investigate the use of intraoperative ultrasound during stage I InterStim® sacral lead placement. METHODS: A total of 40 patients were randomly assigned to undergo InterStim® lead placement utilizing fluoroscopy or ultrasound guidance. Patients were blinded for the duration of the study. The surgeon and staff were blinded until after induction of anesthesia. Patients met criteria for refractory overactive bladder, fecal incontinence, or both. The ICIQ-OABqol, OABSS, and FIQL validated questionnaires were used pre- and post-operatively...
February 21, 2018: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/29450441/failures-of-sacral-neuromodulation-for-incontinence
#20
Bilal Chughtai, Dominique Thomas, Tianyi Sun, Art Sedrakyan
No abstract text is available yet for this article.
February 14, 2018: JAMA Surgery
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