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Sacral neuromodulation

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https://www.readbyqxmd.com/read/28226850/the-effect-of-inter-electrode-distance-on-the-electric-field-distribution-during-transcutaneous-lumbar-spinal-cord-direct-current-stimulation
#1
Rui Bastos, Sofia R Fernandes, Ricardo Salvador, Cornelia Wenger, Mamede A de Carvalho, Pedro C Miranda, Rui Bastos, Sofia R Fernandes, Ricardo Salvador, Cornelia Wenger, Mamede A de Carvalho, Pedro C Miranda, Pedro C Miranda, Rui Bastos, Cornelia Wenger, Ricardo Salvador, Mamede A de Carvalho, Sofia R Fernandes
Previous studies have indicated potential neuromodulation of the spinal circuitry by transcutaneous spinal direct current stimulation (tsDCS), such as changes in motor unit recruitment, shortening of the peripheral silent period and interference with supraspinal input to lower motor neurons. All of these effects were dependent on the polarity of the electrodes. The present study investigates how the distance between the electrodes during tsDCS influences the electric field's (E-field) spatial distribution in the lumbar and sacral spinal cord (SC)...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28224396/sacral-neuromodulation-implant-infection-risk-factors-and-prevention
#2
REVIEW
Calvin Lee, Javier Pizarro-Berdichevsky, Marisa M Clifton, Sandip P Vasavada
Device infection is one of the most common complications of sacral nerve stimulator placement and occurs in approximately 3-10% of cases. Infection is a serious complication, as it often requires complete explantation of the device. Not much is known regarding risk factors for and methods of preventing infection in sacral nerve stimulation. Multiple risk factors have been linked to device infection including prolonged percutaneous testing and choice of preoperative antibiotic. Methods of infection prevention have also been studied recently, including antibiotic-impregnated collage and type of skin preparation...
February 2017: Current Urology Reports
https://www.readbyqxmd.com/read/28218218/effects-of-appropriate-prolonged-sacral-neuromodulation-testing-in-improving-implantation-rate-of-a-permanent-implantable-pulse-generator-in-patients-with-refractory-lower-urinary-tract-dysfunctions-in-mainland-china
#3
Peng Zhang, Jian-Zhong Zhang, Li-Yang Wu, Xiao-Dong Zhang
BACKGROUND: Sacral neuromodulation (SNM) has become an effective method for treating lower urinary tract voiding dysfunction during the past 20 years. Because of the expensive cost, the number of implantable pulse generator (IPG) implantations per year in China is far lower than that in Western developed countries since 2012. This study was to summarize the effects of the appropriate prolonged SNM testing time in improving the implantation rate of a permanent IPG in patients with refractory lower urinary tract symptoms (LUTS) in mainland China...
2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28211186/sacral-neuromodulation-compared-with-injection-of-bulking-agents-for-faecal-incontinence-following-obstetric-anal-sphincter-injury-a-randomised-controlled-trial
#4
M Rydningen, T Dehli, T Wilsgaard, A Rydning, M Kumle, R O Lindsetmo, S Norderval
AIM: The purpose of this trial was to compare the effectiveness of sacral neuromodulation (SNM) with a sub-mucosal injection of collagen (Permacol(®) ) in women with faecal incontinence following obstetric anal sphincter injury (OASIS). METHOD: This single blinded randomized controlled trial at two hospital units in Norway included women with faecal incontinence following OASIS. Eligible women who had had a successful percutaneous nerve evaluation were randomly assigned to SNM or Permacol(®) ...
February 17, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/28192077/impact-of-age-and-comorbidities-on-utilization-of-sacral-neuromodulation
#5
Anna Er Faris, Bradley C Gill, Javier Pizarro-Berdichevsky, Elodi Dielubanza, Marisa M Clifton, Henry Okafor, Howard B Goldman, Courtenay K Moore, Raymond R Rackley, Sandip P Vasavada
PURPOSE: To investigate the influence of patient age on sacral nerve stimulation(SNS) trial outcomes, device implantation, and treatment durability. MATERIALS AND METHODS: A database of all SNS procedures between 2012-2014 at a high-volume institution was analyzed for associations of age with SNS indication, trial stimulation success, device revision, and device explantation. RESULTS: Within a 356 patient cohort, non-obstructive urinary retention and urgency- frequency patients were younger than those with urgency urinary incontinence...
February 10, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28170477/onabotulinumtoxina-vs-sacral-neuromodulation-for-urgency-incontinence-reply
#6
LETTER
Cindy L Amundsen, Holly E Richter, Dennis Wallace
No abstract text is available yet for this article.
7, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28170474/onabotulinumtoxina-vs-sacral-neuromodulation-for-urgency-incontinence
#7
LETTER
John F McCauley, Hector M Gonzalez, David James Osborn
No abstract text is available yet for this article.
7, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28170473/onabotulinumtoxina-vs-sacral-neuromodulation-for-urgency-incontinence
#8
LETTER
Bertil F M Blok
No abstract text is available yet for this article.
7, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28160010/the-effect-of-sacral-neuromodulation-on-pregnancy-a-systematic-review
#9
Amr Mahran, Alex Soriano, Ahmed S Safwat, Adonis Hijaz, Sangeeta T Mahajan, Emanuel C Trabuco, Steven W Siegel, Sherif A El-Nashar
INTRODUCTION AND HYPOTHESIS: To evaluate the effects of sacral neuromodulation (SNM) on pregnancy and the impact of delivery on SNM function. METHODS: A systematic search was conducted through January 2016. We selected studies including women who had SNM and a subsequent pregnancy. RESULTS: Out of 2,316, eight studies were included, comprising 22 patients (26 pregnancies). SNM indications were Fowler's syndrome in 11, urinary retention in 6, fecal incontinence in 1, fecal and urinary urgency in 1, overactive bladder in 1, intractable interstitial cystitis in 1, and myelodysplasia in 1...
February 3, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28159117/fecal-incontinence-treated-by-sacral-neuromodulation-long-term-follow-up-of-325-patients
#10
Paul T J Janssen, Sara Z Kuiper, Laurents P S Stassen, Nicole D Bouvy, Stephanie O Breukink, Jarno Melenhorst
BACKGROUND: Long-term results of large patient cohorts with fecal incontinence treated by sacral neuromodulation are limited. This study shows the long-term results after a mean follow-up of 7.1 years in 325 patients with fecal incontinence treated by continuous sacral neuromodulation. METHODS: All patients with fecal incontinence and eligible for sacral neuromodulation between 2000 and 2015 were evaluated retrospectively. Primary outcome was a decrease in episodes of fecal incontinence, which was defined as involuntary fecal loss at least once per week and documented by a 3 week bowel habit diary...
January 31, 2017: Surgery
https://www.readbyqxmd.com/read/28093307/the-impact-of-baseline-functional-bladder-capacity-on-short-term-neuromodulation-outcomes
#11
Kim A Killinger, Priyanka Gupta, Jason P Gilleran, Jamie Bartley, Michael Ehlert, Judith A Boura, Kenneth M Peters
OBJECTIVES: To evaluate the impact of functional bladder capacity (FBC) on clinical outcomes after a staged neuromodulation procedure. METHODS: Adults in our prospective neuromodulation database were evaluated. Data were collected from medical records, voiding diaries (FBC defined as average volume per void), Interstitial Cystitis Symptom/Problem Indices (ICSI-PI), Overactive Bladder Questionnaires (OAB-q), and Global Response Assessments over 3 months. Descriptive statistics, Pearson's Chi-square tests, Wilcoxon rank sum tests, logistic regression, repeated measures analyses and Spearman Correlation Coefficients were performed...
January 13, 2017: Urology
https://www.readbyqxmd.com/read/28089729/urinary-biomarkers-in-women-with-refractory-urgency-urinary-incontinence-randomized-to-sacral-neuromodulation-versus-onabotulinumtoxina-compared-to-controls
#12
Holly E Richter, Pamela Moalli, Cindy L Amundsen, Anna P Malykhina, Dennis Wallace, Rebecca Rogers, Deborah Myers, Maria Paraiso, Michael Albo, Haolin Shi, Tracy Nolen, Susie Meikle, R Ann Word
PURPOSE: To measure urinary biomarker levels in women with refractory urgency urinary incontinence (UUI) and controls at baseline and 6 months post treatment from sacral neuromodulation (SNM) or intradetrusor injection onabotulinumtoxinA and to assess association of baseline biomarkers to post treatment UUI episodes (UUIE) and overactive bladder (OAB) symptom bother outcomes. MATERIALS AND METHODS: First morning urines were collected from consented trial participants and age-matched women without UUI...
January 13, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28057156/-short-term-outcome-of-sacral-neuromodulation-on-refractory-interstitial-cystitis-pelvic-pain-syndrome
#13
P Zhang, J Z Zhang, L Y Wu, H Q Niu, Y B Yang, X D Zhang
Objective: To summarize the initial experiences of applying sacral neuromodulation (SNM) for refractory interstitial cystitis/pelvic pain syndrome (IC/PPS). Methods: From January 2013 to August 2016, 26 patients with refractory IC/PPS (including 5 males and 21 females) treated with SNM were recruited in Beijing Chaoyang Hospital and Hebei Yanda Hospital in this retrospective study. The data before operation, after implantation of stage Ⅰ tined lead, and during short-term follow-up after implantation of stage Ⅱ implanted pulse generator (IPG) were compared in order to observe the improvement of relevant symptoms, and to summarize the effectiveness and safety of SNM for IC/PPS...
December 27, 2016: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28034599/neuraxial-analgesia-in-a-pregnant-woman-with-fowler-s-syndrome-and-sacral-neuromodulation
#14
M Ansó, L Veiga-Gil, J De Carlos, A Hualde, J Pérez-Cajaraville
We report the anesthetic management of a 16-year-old woman with Fowler's syndrome who became pregnant three years after sacral neuromodulation was initiated for treatment of the condition. Multidisciplinary consensus was to switch off the neurostimulator during pregnancy, and attempt vaginal delivery with a neuraxial block. When the patient was admitted for labor, an epidural catheter was placed successfully. The patient had a normal vaginal delivery. Sacral neuromodulation was restarted uneventfully in the early puerperium and the Fowler's syndrome remains well controlled...
December 5, 2016: International Journal of Obstetric Anesthesia
https://www.readbyqxmd.com/read/28000184/-to-improve-the-surgical-outcome-of-chronic-constipation-from-bed-to-the-bench
#15
Weidong Tong, Li Wang
The prevalence of chronic constipation is about 16% in adults, and increases with age, especially after 60 years old. Usually, surgical intervention is recommended to patients with long standing intractable constipation, who have undergone various conservative therapies. Lots of surgical procedures have been reported for different kinds of constipation, including slow transit, outlet obstruction, etc. For slow transit constipation, total or subtotal colectomy is commonly used. Merely for the internal rectal prolapse, at least 10 procedures are commonly adopted in clinic...
December 25, 2016: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/27988174/-medico-economic-evaluation-of-urological-cares-of-spinal-cord-injured-patients-a-review
#16
C Guillot-Tantay, E Chartier-Kastler, Q Manach, M-A Perrouin-Verbe, P Denys, V Phé
INTRODUCTION: To provide an overview of the urological management of spinal cord injured patients based on an economic analysis. MATERIALS AND METHODS: A literature search from January 1994 to December 2014 was performed using Medline and Embase database using the following keywords: cost-effectiveness; cost-benefit; cost-utility; spinal cord injury; neurogenic bladder; intermittent catheterization; antimuscarinics; botulinum toxin; sacral neuromodulation; tibial nerve; Brindley; sphincterotomy...
January 2017: Progrès en Urologie
https://www.readbyqxmd.com/read/27935110/involvement-of-opioid-receptors-in-inhibition-of-bladder-overactivity-induced-by-sacral-neuromodulation-in-pigs-a-possible-action-mechanism
#17
Xing Li, Limin Liao, Guoqing Chen, Zhaoxia Wang, Han Deng
AIMS: To determine the role of opioid receptors in the inhibition of bladder overactivity by sacral neuromodulation (SNM) in pigs, and explore the possible mechanism of SNM. METHODS: Both implant-driven stimulators of the S3 spinal nerve were implanted in seven pigs. Naloxone and tramadol were administered. Multiple cystometrograms were performed to determine the effects of SNM and opioid receptors on the micturition reflex by infusing normal saline (NS) or acetic acid (AA)...
December 9, 2016: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/27920880/conditional-electrical-stimulation-in-animal-and-human-models-for-neurogenic-bladder-working-toward-a-neuroprosthesis
#18
C R Powell
Sacral neuromodulation has had a tremendous impact on the treatment of urinary incontinence and lower urinary tract symptoms for patients with neurologic conditions. This stimulation does not use real-time data from the body or input from the patient. Incorporating this is the goal of those pursuing a neuroprosthesis to enhance bladder function for these patients. Investigators have demonstrated the effectiveness of conditional (also called closed-loop) feedback in animal models as well as limited human studies...
December 2016: Current Bladder Dysfunction Reports
https://www.readbyqxmd.com/read/27915486/evaluation-of-the-axonics-modulation-technologies-sacral-neuromodulation-system-for-the-treatment-of-urinary-and-fecal-dysfunction
#19
Joshua A Cohn, Casey G Kowalik, Melissa R Kaufman, W Stuart Reynolds, Douglas F Milam, Roger R Dmochowski
Sacral neuromodulation (SNM) remains one of the few effective treatments for refractory bladder and bowel dysfunction. However, SNM is associated with frequent need for surgical intervention, in many cases because of a failed battery. A rechargeable SNM system, with a manufacturer-reported battery life of 15 years or more, has entered post-market clinical testing in Europe but has not yet been approved for clinical testing in the United States. Areas covered: We review existing neuromodulation technologies for the treatment of lower urinary tract and bowel dysfunction and explore the limitations of available technology...
January 2017: Expert Review of Medical Devices
https://www.readbyqxmd.com/read/27885800/sacral-neuromodulation-for-the-treatment-of-faecal-incontinence-following-proctectomy
#20
Ido Mizrahi, Sami A Chadi, Nadav Haim, Dana R Sands, Brooke Gurland, Massarat Zutshi, Steven D Wexner, Giovanna da Silva
AIM: This study assessed the effectiveness of sacral neuromodulation (SNM) for faecal incontinence (FI) following proctectomy with colorectal or coloanal anastomosis. METHODS: An IRB-approved database identified patients treated for FI following proctectomy (SNM-P) for benign or malignant disease, who were matched 1:1 by pre-operative Cleveland Clinic Florida Faecal Incontinence Scores (CCF-FIS) with patients without proctectomy (SNM-NP). Primary outcome was change in CCF-FIS...
November 25, 2016: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
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