Arash Sarveazad, Abazar Yari, Farnad Imani, Farimah Fayyaz, Marjan Mokhtare, Arash Babaei-Ghazani, Mahmoud Yousefifard, Shahriar Sarveazad, Siavash Assar, Jebreil Shamseddin, Mansour Bahardoust
INTRODUCTION: Fecal incontinence (FI) is caused by external anal sphincter injury. Vitamin E is a potential strategy for anal sphincter muscle repair via its antioxidant, anti-inflammatory, anti-fibrotic, and protective properties against myocyte loss. Thus, we aimed to evaluate the water-soluble form of vitamin E efficacy in repairing anal sphincter muscle defects in rabbits. METHODS: Twenty-one male rabbits were equally assigned to the intact (without any intervention), control (sphincterotomy), and Trolox (sphincterotomy + Trolox administration) groups...
June 20, 2023: BMC Gastroenterology