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https://www.readbyqxmd.com/read/27643694/late-cardiac-events-after-childhood-cancer-methodological-aspects-of-the-pan-european-study-pancaresurfup
#1
Elizabeth A M Feijen, Anna Font-Gonzalez, Elvira C van Dalen, Helena J H van der Pal, Raoul C Reulen, David L Winter, Claudia E Kuehni, Riccardo Haupt, Daniela Alessi, Julianne Byrne, Edit Bardi, Zsuzsanna Jakab, Desiree Grabow, Stanislaw Garwicz, Momcilo Jankovic, Gill A Levitt, Roderick Skinner, Lorna Zadravec Zaletel, Lars Hjorth, Wim J E Tissing, Florent de Vathaire, Mike M Hawkins, Leontien C M Kremer
BACKGROUND AND AIM: Childhood cancer survivors are at high risk of long-term adverse effects of cancer and its treatment, including cardiac events. The pan-European PanCareSurFup study determined the incidence and risk factors for cardiac events among childhood cancer survivors. The aim of this article is to describe the methodology of the cardiac cohort and nested case-control study within PanCareSurFup. METHODS: Eight data providers in Europe participating in PanCareSurFup identified and validated symptomatic cardiac events in their cohorts of childhood cancer survivors...
2016: PloS One
https://www.readbyqxmd.com/read/23836424/changes-in-neuron-specific-enolase-are-more-suitable-than-its-absolute-serum-levels-for-the-prediction-of-neurologic-outcome-in-hypothermia-treated-patients-with-out-of-hospital-cardiac-arrest
#2
Michael Huntgeburth, Christoph Adler, Stephan Rosenkranz, Carsten Zobel, Walter F Haupt, Christian Dohmen, Hannes Reuter
BACKGROUND: To determine neurologic outcome in patients with out-of-hospital cardiac arrest (OHCA) and treatment with mild therapeutic hypothermia (MTH). METHODS: Seventy-three consecutive OHCA patients treated with MTH were retrospectively analyzed. Serum neuron-specific enolase (NSE) was measured 24, 48, and 72 h after admission. In patients with no motor response 48 h after termination of analgosedation (n = 40), clinical neurological examination and evoked potentials (EPs) were determined...
June 2014: Neurocritical Care
https://www.readbyqxmd.com/read/23698819/anterior-mediastinal-thymoma-compressing-the-right-ventricular-outflow-tract-rvot-causing-syncope
#3
Vidushi Sharma, Christine Rohr, Susan Sallach, Butchi Babu Paidipaty, Marilyn Haupt
SESSION TYPE: Cancer Student/Resident Case Report PostersPRESENTED ON: Tuesday, October 23, 2012 at 01:30 PM - 02:30 PMINTRODUCTION: The comman Anterior mediastinal masses found in the anterior mediastinum are thymomas, lymphomas, germ cell tumors, congenital cysts, intrathoracic thyroid tissue, and parathyroid lesions1. Common clinical presentations of the mediastinal masses include dyspnea on exertion, arrhythmias, right-sided heart failure, pericarditis, pericardial effusion, and syncope.1 Thymomas represent 20 percent of all mediastinal neoplasms in adults and is found in 15 percent of patients with myasthenia gravis...
October 1, 2012: Chest
https://www.readbyqxmd.com/read/23243401/sleep-related-expiratory-obstructive-apnea-in-children
#4
Mark E Haupt, Denise M Goodman, Stephen H Sheldon
STUDY OBJECTIVES: We describe the respiratory, cardiac, and sleep-related characteristics of two types of sleep-related respiratory pauses in children that can fulfill current criteria of pathological apnea, but often seem to be benign: prolonged expiratory apnea (PEA) and post-sigh central apnea (PSCA). METHODS: All outpatient comprehensive overnight polysomnography completed on children without significant underlying medical conditions completed during an 18-month period were retrospectively reviewed for the presence of augmented breaths followed by a respiratory pause...
December 15, 2012: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/19336430/percutaneous-intramyocardial-stem-cell-injection-in-patients-with-acute-myocardial-infarction-first-in-man-study
#5
K Krause, K Jaquet, C Schneider, S Haupt, M V Lioznov, K-M Otte, K-H Kuck
BACKGROUND: Clinical studies on intracoronary stem cell infusion in patients with acute myocardial infarction (AMI) have shown promising results for left ventricular ejection fraction (LVEF). However, preclinical studies have shown that intramyocardial cell injection is better than the intracoronary approach. OBJECTIVE: To test safety and feasibility of intramyocardial cell injection and left ventricular electromechanical mapping (EMM) early after AMI. DESIGN: On day 10...
July 2009: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/11096824/-toxic-and-less-toxic-plants
#6
H Haupt
No abstract text is available yet for this article.
June 2000: Kinderkrankenschwester: Organ der Sektion Kinderkrankenpflege
https://www.readbyqxmd.com/read/9617879/study-of-platelet-activating-factor-acetylhydrolase-in-the-perioperative-period-of-patients-undergoing-cardiac-surgery
#7
M Schlame, A B Schmid, R Haupt, B Rüstow, W J Kox
After operations with cardiopulmonary bypass, patients often show early symptoms of the systemic inflammatory response syndrome (SIRS). Potential mediators of SIRS include the platelet-activating factor (PAF), which has been linked to septic shock and multiple organ dysfunction. We studied the effect of cardiac surgery on PAF acetylhydrolase, the PAF-degrading plasma enzyme, as well as the relationship between the enzyme and the postoperative state of the patients. PAF acetylhydrolase activity decreased by 38+/-8% after instituting cardiopulmonary bypass because of plasma dilution and returned to near-preoperative levels within 6 h postsurgery...
May 1998: Shock
https://www.readbyqxmd.com/read/8037995/cardiac-release-of-chemoattractants-after-ischaemia-induced-by-coronary-balloon-angioplasty
#8
F J Neumann, G Richardt, M Schneider, I Ott, H M Haupt, H Tillmanns, A Schömig, B Rauch
OBJECTIVE: To investigate the release of chemoattractants after myocardial ischaemia during balloon angioplasty. DESIGN: Sampling of femoral arterial and coronary sinus blood before and immediately after the first balloon inflation during angioplasty. In a study group of 16 patients the balloon was kept expanded for two minutes, whereas in a control group of eight patients the first balloon inflation was brief (< 10 s). MAIN OUTCOME MEASURES: Chemotaxis of neutrophils from healthy donors towards patient plasma (Boyden chamber), superoxide anion production by normal neutrophils after incubation with patient plasma (cytochrome C reduction)...
July 1993: British Heart Journal
https://www.readbyqxmd.com/read/7838785/early-changes-in-defibrillation-threshold-following-implantation-of-a-nonthoracotomy-system-in-dogs
#9
B D Halperin, D W Haupt, J H Lemmer, S R Holcomb, R P Oliver, M J Silka
BACKGROUND: Nonthoracotomy systems are rapidly becoming the preferred surgical method for implantation of cardioverter defibrillators. Testing is performed at the time of implantation to insure an adequate margin of safety for defibrillation. However, this safety margin may change with lead maturation. This study evaluated changes in defibrillation threshold following implantation of a nonthoracotomy system. METHODS AND RESULTS: Ten dogs underwent implantation of a nonthoracotomy system consisting of a single catheter with a distal coil electrode in the right ventricular apex and a proximal coil electrode in the superior vena cava forming a common anode with a subcutaneous patch over the left thorax...
November 1994: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/7770364/use-of-adenosine-to-identify-patients-at-risk-for-recurrence-of-accessory-pathway-conduction-after-initially-successful-radiofrequency-catheter-ablation
#10
K W Walker, M J Silka, D Haupt, J Kron, J H McAnulty, B D Halperin
OBJECTIVE: The use of adenosine after radiofrequency catheter ablation of accessory pathways was prospectively studied to determine its utility for identifying patients at risk for recurrence of accessory pathway conduction and to guide therapy that might reduce late recurrence in this group. BACKGROUND: Accessory pathway conduction recurs in 5%-12% of patients following initially "successful" radiofrequency catheter ablation. Adenosine may facilitate conduction over accessory pathways that have been modified by radiofrequency delivery, thus identifying patients at risk for recurrence...
March 1995: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/7137049/the-heart-and-cardiac-conduction-system-in-polymyositis-dermatomyositis-a-clinicopathologic-study-of-16-autopsied-patients
#11
H M Haupt, G M Hutchins
We reviewed the clinical records of 16 patients with polymyositis-dermatomyositis syndromes autopsied at The Johns Hopkins Hospital to determine the nature and extent of cardiac involvement and its correlation with the severity of disease as a whole. The adult patients ranged in age from 32 to 84 years (average 56); the 2 children were aged 2 and 10 years. The duration of disease ranged from 1 to 72 months (average 21). Seven patients had dermatomyositis, 5 had dermatomyositis with malignancy, 2 had childhood dermatomyositis, and 2 had an overlap syndrome...
November 1982: American Journal of Cardiology
https://www.readbyqxmd.com/read/6705387/erdheim-chester-disease-a-case-report
#12
G G Poehling, D M Adair, H A Haupt
In a 57-year-old woman dizziness, staggering, altered mental status, and bilateral pain and cramping in the lower extremities developed. Extensive investigation yielded evidence of renal and long-bone lesions, with the latter being primarily metaphyseal and diaphyseal. Needle biopsy of the tibial marrow revealed the presence of lipid-laden histiocytes, osteosclerosis, and osteoclasts. A diagnosis of Erdheim-Chester disease was made; this is the 16th known case of the disease. The patient responded well to steroid therapy but later was readmitted and ultimately died of extensive infiltrates in the kidneys and pancreas...
May 1984: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/6194934/fluid-resuscitation-in-circulatory-shock-a-comparison-of-the-cardiorespiratory-effects-of-albumin-hetastarch-and-saline-solutions-in-patients-with-hypovolemic-and-septic-shock
#13
RANDOMIZED CONTROLLED TRIAL
E C Rackow, J L Falk, I A Fein, J S Siegel, M I Packman, M T Haupt, B S Kaufman, D Putnam
Twenty-six consecutive patients in hypovolemic shock were randomized to fluid challenge with 5% albumin (A), 6% hetastarch (H), or 0.9% saline (S) solutions. Fluid challenge consisted of 250 ml of test fluid every 15 min until the pulmonary artery wedge pressure (WP) reached 15 mm Hg. Thereafter, WP was maintained at 15 mm Hg for an additional 24 h with infusions of the same test fluid. Vital signs, hemodynamic and respiratory variables, as well as arterial lactate and colloid osmotic pressure (COP) were monitored according to protocol...
November 1983: Critical Care Medicine
https://www.readbyqxmd.com/read/3211244/-spontaneous-pontine-hemorrhage-an-analysis-of-38-cases
#14
H Bewermeyer, C Hojer, B Szelies, W F Haupt, M Neveling, W D Heiss
In 38 patients suffering from spontaneous pontine hemorrhages arterial hypertension was the most common risk factor. 31 patients, of whom 30 died, suffered centro-paramedian pontine hemorrhage leading to coma, hypertensive crisis, respiratory failure, cardiac arrhythmia, miosis and tetraparesis. Most cases showed involvement of the mesencephalon [17] and fourth ventricle [14]. The other seven patients demonstrated dorsotegmental [5] or hemipontine [2] hemorrhages with complex neuroophthalmologic signs, other cranial nerve lesions, and ataxia or hemiparesis; all these patients survived, some even without neurological deficit...
November 1988: Der Nervenarzt
https://www.readbyqxmd.com/read/2759111/haemorheologic-studies-in-patients-with-reduced-coronary-vasodilator-capacity-but-normal-coronary-angiogram-syndrome-x
#15
F J Neumann, W Waas, R Zimmermann, H Haupt, H Tillmanns, W Kübler
The cause of syndrome X, i.e. typical angina, positive exercise test, normal coronary angiogram, normal resting cardiac function, but reduced coronary vasodilator capacity is still unknown. The purpose of the study was to investigate blood fluidity as a possible cause of syndrome X. Haematocrit, plasma viscosity, erythrocyte aggregation, and erythrocyte deformability were examined in 14 patients with syndrome X (group 1), 24 patients with typical angina, positive exercise test, but normal coronary vasodilator capacity (group 2), and 37 patients with atypical chest pain and normal coronary arteries (control group)...
June 1989: European Heart Journal
https://www.readbyqxmd.com/read/2369232/extension-of-donor-criteria-in-cardiac-transplantation-surgical-risk-versus-supply-side-economics
#16
M S Sweeney, D E Lammermeier, O H Frazier, C M Burnett, H M Haupt, J M Duncan
To combat the continuing shortage of ideal donor hearts, we have used cardiac allografts from high-risk donors for critically ill recipients. We defined high-risk donor variables as age greater than 40 years, systemic (noncardiac) infection, cardiopulmonary resuscitation greater than 3 minutes, ischemic time longer than 5 hours, weight more than 20% less than that of the recipient, and requirements for high doses of inotropes. Of the 305 donors we have used, 73 (23.9%) have been high-risk, with 59/73 (80.8%) exhibiting one variable, 12/73 (16...
July 1990: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/2166490/use-of-potentially-infected-donor-hearts-for-cardiac-transplantation
#17
D E Lammermeier, M S Sweeney, H E Haupt, B Radovancevic, J M Duncan, O H Frazier
Despite the nationwide shortage of heart donors, more patients, some of whom are critically ill, are being accepted as candidates for transplantation. Thus, on occasion, we have liberalized our donor criteria to meet the demand. We have recently transplanted 16 potentially infected donor hearts into critically ill recipients. Of these 16 donors, 7 had multiple positive blood cultures as follows: Streptococcus pneumoniae (3), Staphylococcus aureus (2), Klebsiella pneumoniae (1), and Enterobacter sp (1). Seven other donors were accepted despite high fevers (rectal temperature greater than 38...
August 1990: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/1959372/hemodynamic-responses-to-gram-positive-versus-gram-negative-sepsis-in-critically-ill-patients-with-and-without-circulatory-shock
#18
A J Ahmed, J A Kruse, M T Haupt, P H Chandrasekar, R W Carlson
OBJECTIVE: To examine the hemodynamic patterns of critically ill patients with septicemia to evaluate their relationship to blood bacteriology. DESIGN: Retrospective study. SETTING: Medical ICUs of a tertiary care medical center. PATIENTS: Total of 59 critically ill patients with bacteremia: 33 with Gram-positive and 26 with Gram-negative bacteremia. MEASUREMENTS: Hemodynamic variables and mixed venous oxygen saturation (SvO2) measurements associated with the highest cardiac index measured within 72 hrs of positive blood cultures...
December 1991: Critical Care Medicine
https://www.readbyqxmd.com/read/1772707/increased-plasma-viscosity-and-erythrocyte-aggregation-indicators-of-an-unfavourable-clinical-outcome-in-patients-with-unstable-angina-pectoris
#19
F J Neumann, H A Katus, E Hoberg, P Roebruck, M Braun, H M Haupt, H Tillmanns, W Kübler
OBJECTIVE: To determine the prognostic significance of altered plasma viscosity and erythrocyte aggregation in unstable angina. DESIGN: A prospective study of 96 consecutive patients with unstable angina allocated to one of two groups according to predefined threshold values for plasma viscosity and erythrocyte aggregation at study entry. The patients received a standardised treatment and were followed up for six months or until angioplasty or bypass surgery. MAIN OUTCOME MEASURE: Frequency of myocardial infarction...
December 1991: British Heart Journal
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