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HM Haupt

Eftyhia Vardas, Anna R Giuliano, Stephen Goldstone, Joel M Palefsky, Edson D Moreira, Mary E Penny, Carlos Aranda, Heiko Jessen, Harald Moi, Daron G Ferris, Kai-Li Liaw, J Brooke Marshall, Scott Vuocolo, Eliav Barr, Richard M Haupt, Elizabeth I O Garner, Dalya Guris
BACKGROUND: We examined the baseline prevalence of penile, scrotal, and perineal/perianal human papillomavirus (HPV) in heterosexual men (HM). We also evaluated baseline characteristics of HM to assess factors associated with prevalent HPV detection. METHODS: We tested serum samples from 3463 HM aged 16-24 years with 1-5 lifetime female sexual partners for antibodies to HPV 6, 11, 16, and 18. We collected baseline swab specimens for the detection of DNA of HPV 6, 11, 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, and 59 from 3 areas: penile, scrotal, and perineal/perianal...
January 1, 2011: Journal of Infectious Diseases
S Moody-Haupt, J H Patterson, D Mirelman, M J McConville
Trophozoites of the parasitic protozoa, Entamoeba histolytica, synthesize a cell surface lipoglycoconjugate, termed lipophosphoglycan, which is thought to be an important virulence factor and potential vaccine candidate against invasive amebiasis. Here, we show that the E. histolytica lipophosphoglycans are in fact glycosylphosphatidylinositol (GPI)-anchored proteophosphoglycans (PPGs). These PPGs contain a highly acidic polypeptide component which is rich in Asp, Glu and phosphoserine residues. This polypeptide component is extensively modified with linear glycan chains having the general structure, [Glcalpha1-6](n)Glcbeta1-6Gal (where n=2-23)...
March 24, 2000: Journal of Molecular Biology
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