keyword
https://read.qxmd.com/read/38431895/lateralizing-calcaneal-osteotomy-performed-with-a-percutaneous-burr-results-in-a-significantly-lower-increase-in-tarsal-tunnel-pressure
#1
JOURNAL ARTICLE
Ali A Siddiqui, Wesley D Troyer, Jugert Bango, Moawiah S Mustafa, Jeannie F Buckner, Glenn G Shi, Edward T Haupt
PURPOSE: Tarsal tunnel syndrome is well documented following lateralizing calcaneal osteotomy to manage varus hindfoot deformity. Traditionally, calcaneal osteotomy is performed with an oscillating saw. No studies have investigated the effect of alternative surgical techniques on postoperative tarsal tunnel pressure. The purpose of this study was to investigate the difference in tarsal tunnel pressures following lateralizing calcaneal osteotomy performed using a high-torque, low-speed "minimally invasive surgery" (MIS) Shannon burr versus an oscillating saw...
March 3, 2024: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://read.qxmd.com/read/37567029/renal-medullary-carcinoma-a-surveillance-epidemiology-and-end-results-seer-analysis
#2
JOURNAL ARTICLE
Thomas Haupt, Oluwasegun Akinyemi, Richu A Raju, Andrew E Wadley, Siobhan Nnorom, Vanessa Aponte, Jennifer Thelus, Jeremy B Tonkin, Pamela W Coleman, Adam R Metwalli
INTRODUCTION: Renal medullary carcinoma (RMC) is an aggressive and rare renal malignancy that predominantly affects Black patients but is also found in individuals of other ethnicities. To date, only a few hundred cases have been reported in the urologic literature. Due to this extreme rarity, the exact pathophysiology and optimal treatment have yet to be well described. This study aims to determine the predictors of mortality and overall survival outcomes in patients with RMC. METHODS: We utilized the Surveillance, Epidemiology, and End Results Program (SEER) database 18 registries to retrieve demographic and clinical information on patients with RMC between 1996 and 2018...
August 9, 2023: Journal of Surgical Research
https://read.qxmd.com/read/37276035/underutilization-or-appropriate-care-assessing-adjuvant-chemotherapy-use-and-survival-in-3-heterogenous-subpopulations-with-stage-ii-iii-colorectal-cancer-within-a-large-integrated-health-system
#3
JOURNAL ARTICLE
Yilin Chen, Veena Shankaran, Erin E Hahn, Eric C Haupt, Aasthaa Bansal
BACKGROUND: Clinical guidelines have recommended adjuvant chemotherapy (ACT) for patients with high-risk stage II colon cancer, although the survival benefit is unclear. ACT is also recommended for patients with stage III colon cancer to reduce the risk of recurrence and mortality. For stage II/III rectal cancer, however, the role of perioperative chemotherapy (PCT, adjuvant or neoadjuvant) remains controversial, resulting in substantial variation in its use in clinical practice. OBJECTIVES: To understand real-world use and predictors of ACT or PCT use and survival outcomes in 3 heterogeneous patient groups with colorectal cancer (CRC), and to inform the evidence gap between guideline-based care and clinical practice...
June 2023: Journal of Managed Care & Specialty Pharmacy
https://read.qxmd.com/read/37275117/quantitative-ergonomic-comparison-of-traditional-versus-endoscopic-assisted-tonsillectomies-a-prospective-case-control-study
#4
JOURNAL ARTICLE
Thomas L Haupt, Andrew Wadley, Jamil Hayden, Earl H Harley
Objective: Quantitatively compare the ergonomics of traditional tonsillectomy versus an endoscopic-assisted tonsillectomy. Methods: The physical positioning of the senior author was studied during a simulation of two different operative approaches to tonsillectomy: one using an endoscope and one using direct visualization without the aid of an endoscope. Whole-body postural data was collected and analyzed using the validated Rapid Upper Limb Assessments (RULA) tool to calculate the risk of musculoskeletal injuries...
June 2023: Indian Journal of Otolaryngology and Head and Neck Surgery
https://read.qxmd.com/read/37224221/ultrasonographic-identification-of-shell-surface-types-in-commercially-available-silicone-gel-filled-breast-implants
#5
JOURNAL ARTICLE
Giovanni Herrera-Mora, Pablo Solis-Chaves, Georgina Hernandez-Aviles, Emma-Jane M Graham, Christine Clausen-Oreamuno, Jose Andres Castro-Cespedes, Jennifer Haupt, Morgan Jamiel, Omid Veiseh, Marcos Sforza, John Hancock, Brian Kinney, Roberto De Mezerville, Robert Langer, Joshua C Doloff, Manuel Chacon-Quiros
BACKGROUND: Breast implant safety issues have resulted in the need for global product recalls and medical device tracing. Conventional methods of breast implant tracing, have to date proven to be unsuccessful. This study aims to evaluate the effectiveness of HRUS screening in identifying implanted breast devices. METHODS: Data from 113 female patients undergoing pre-operative ultrasound screening for secondary breast surgery between 2019 and 2022 was prospectively reviewed to evaluate the effectiveness of HRUS imaging with the aid of a Sonographic Surface Catalog to identify the surface and brand type of implanted breast devices...
May 24, 2023: Plastic and Reconstructive Surgery
https://read.qxmd.com/read/37030445/clinical-phenotype-of-adolescent-and-adult-patients-with-extracranial-vascular-malformation
#6
JOURNAL ARTICLE
A Tuleja, S Bernhard, G Hamvas, T A Andreoti, J Rössler, L M Boon, M Vikkula, R Kammer, F Haupt, Y Döring, I Baumgartner
BACKGROUND: In recent years, genotypic characterization of congenital vascular malformations (CVM) has gained attention; however, the spectrum of clinical phenotype remains difficult to attribute to a genetic cause and is rarely described in the adult population. AIM: The aim of this study is to describe a consecutive series of adolescent and adult patients in a tertiary center, where a multimodal phenotypic approach was used for diagnosis. METHODS: We analyzed clinical findings, imaging, and laboratory results at initial presentation, and set a diagnosis according to the International Society for the Study of Vascular Anomalies (ISSVA) classification for all consecutively registered patients older than 14 years of age who were referred to the Center for Vascular Malformations at the University Hospital of Bern between 2008 and 2021...
April 6, 2023: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://read.qxmd.com/read/37005933/clavicular-hook-plate-versus-dog-bone-technique-for-acute-high-grade-acromioclavicular-joint-dislocation-a-retrospective-cohort-study-comparing-clinical-outcome-scores-complications-and-costs
#7
REVIEW
Silvan Hess, Kerstin Bütler, Samuel Haupt, Holger Grehn, Christoph Sommer, Christian Michelitsch
INTRODUCTION: Arthroscopically assisted coracoclavicular (CC) ligament fixation techniques have been promoted as providing superior outcomes for the treatment of acute high-grade acromioclavicular joint (ACJ) dislocations. Nevertheless, there is a lack of high-level evidence for clinically relevant benefits. At our institute, orthopaedic surgeons use an arthroscopically assisted coracoclavicular ligament fixation technique (DB), while general trauma surgeons use a clavicular hook plate (cHP) technique...
August 2023: Archives of Orthopaedic and Trauma Surgery
https://read.qxmd.com/read/36825255/contemporary-review-autograft-bone-use-in-foot-and-ankle-surgery
#8
REVIEW
Jose M Iturregui, Alex M Moses, Glenn G Shi, Edward T Haupt
UNLABELLED: Bone autografts are frequently harvested for use in foot and ankle surgery. A commonly used harvest site is the iliac crest; however, because of known morbidity with this site, the tibia and calcaneus are attractive alternatives. There remains limited understanding regarding the osteogenic potential of autografts from each of these locations. In this review, we provided an update of the known data on bone autografts from the iliac crest, tibia, and calcaneus, focusing on the total cells harvested from each site as well as the presence of osteogenic osteoprogenitor cells...
January 2023: Foot & ankle orthopaedics
https://read.qxmd.com/read/36744743/patient-satisfaction-and-pain-relief-after-deep-peroneal-nerve-neurectomy-for-midfoot-arthritis-a-preliminary-short-report
#9
COMMENT
Jose M Iturregui, Edward T Haupt, Benjamin K Wilke, Jonathan C Kraus, Glenn G Shi
BACKGROUND: The deep peroneal nerve (DPN) plays a role in afferent nociceptive dorsal midfoot joint pain perception. DPN neurectomy for treatment of symptomatic dorsal midfoot osteoarthritis allows early mobilization and weightbearing. The purpose of our study was to evaluate the patient satisfaction and pain relief after DPN neurectomy for treatment of chronic dorsal midfoot pain due to osteoarthritis. METHODS: In this retrospective, IRB-approved, questionnaire-based study, we evaluated 48 patients (55 feet) with an average follow-up of 35...
March 2023: Foot & Ankle International
https://read.qxmd.com/read/36728033/a-simple-preoperative-score-predicting-failure-following-decompression-surgery-for-degenerative-lumbar-spinal-stenosis
#10
JOURNAL ARTICLE
Dimitris Dimitriou, Elin Winkler, Sabrina Weber, Samuel Haupt, Michael Betz, Mazda Farshad
BACKGROUND CONTEXT: Proper patient selection is crucial for the outcome of surgically treated degenerative lumbar spinal stenosis (DLSS). Nevertheless, there is still not a clear consensus regarding the optimal treatment option for patients with DLSS. PURPOSE: To investigate the treatment failure rate and introduce a simple, preoperative score to aid surgical decision-making. STUDY DESIGN/SETTING: Retrospective observational study. PATIENT SAMPLE: Four-hundred-and-forty-five patients who underwent a surgical decompression for DLSS...
January 19, 2023: Spine
https://read.qxmd.com/read/36603058/accuracy-of-pain-tolerance-self-assessment-versus-objective-pressure-sensitivity
#11
JOURNAL ARTICLE
Edward T Haupt, Giselle M Porter, Timothy Charlton, David Thordarson
INTRODUCTION: Effective treatment of postoperative pain after elective surgery remains elusive, and the experience of pain can be variable for patients. The patient's intrinsic pain tolerance may contribute to this variability. We sought to identify whether there was a correlation between subjective report of intrinsic pain tolerance and objective measurement of pressure dolorimetry (PD). We also sought to identify whether a correlation existed between PD and Patient Reported Outcome Measurement Information System (PROMIS) scores of pain intensity, physical function, and mood...
January 4, 2023: Journal of the American Academy of Orthopaedic Surgeons
https://read.qxmd.com/read/36082428/measuring-deltoid-insufficiency-after-supination-external-rotation-ankle-fracture-with-lateral-talar-subluxation-on-gravity-stress-view
#12
JOURNAL ARTICLE
Edward T Haupt, Ronnie Sebro, Jose M Iturregui, Rupert Stanborough, Ali Siddiqui, Glenn G Shi
BACKGROUND: Stress-view radiographs are frequently obtained to evaluate supination-external rotation (SER) variant ankle fractures. Measurement of the ankle medial clear space (MCS) is a surrogate of medial structure integrity as part of overall ankle stability. Measurement of the lateral talus displacement with respect to the incisura may be a sensitive and specific method to assess joint subluxation. METHODS: Retrospective review of acute SER-variant isolated lateral malleolar fractures with gravity stress views (GSVs) were performed for 103 patients...
December 2022: Foot & Ankle International
https://read.qxmd.com/read/35767041/the-effect-of-lumbar-spinal-fusion-on-native-acetabular-anteinclination-in-standing-position
#13
JOURNAL ARTICLE
Dimitris Dimitriou, Samuel Haupt, Sabrina Weber, Elin Winkler, Michael Betz, Mazda Farshad
PURPOSE: The complex and dynamic spinopelvic interplay is not well understood. The aims of the present study were to investigate the following: (1) whether native acetabular anteinclination (AI) in standing position changes following lumbar spinal fusion (LSF); (2) potential correlations between AI change (ΔAI) and several spinopelvic parameters such as the change in lumbar lordosis (ΔLL), pelvic tilt (ΔPT), and anterior pelvic plane angle (ΔaPP). METHODS: A total of 485 patients (Males: 262, Females: 223) with an average age of 64 ± 13 years who underwent a primary LSF were identified from our institutional database...
June 29, 2022: Archives of Orthopaedic and Trauma Surgery
https://read.qxmd.com/read/35759106/shoulder-arthroplasty-for-proximal-humeral-fracture-treatment-a-retrospective-functional-outcome-analysis
#14
JOURNAL ARTICLE
Sabrina Weber, Holger Grehn, René Hutter, Christoph Sommer, Samuel Haupt
PURPOSE: Following proximal humeral fractures hemiarthroplasty (HA) or reversed total shoulder arthroplasty (rTSA) are performed if osteosynthesis or conservative treatment is not possible. HA has been reported to result in decreased functional outcomes compared with rTSA. Secondary shoulder arthroplasty, performed after a different initial treatment, has also been associated with inferior outcomes. METHODS: Patients recieving a shoulder arthroplasty related to a proximal humeral fracture from 2010 to 2019 were included...
June 27, 2022: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://read.qxmd.com/read/35619626/pelvic-fixation-in-surgical-correction-of-neuromuscular-scoliosis
#15
JOURNAL ARTICLE
Mazda Farshad, Sabrina Weber, José Miguel Spirig, Michael Betz, Samuel Haupt
Background: Surgical correction of neuromuscular scoliosis can be associated with high complication rates, including such associated with pelvic fixation. Up to now it is debated whether and when to include the pelvis into the fusion construct. Therefore, we aimed to illuminate when pelvic fixation is beneficial in surgical correction of neuromuscular scoliosis. Methods: A prospective cohort of 49 patients (mean age 13 ± 3 y, 63% females, follow up 56 months, range 24-215) who underwent correction of neuromuscular scoliosis including S1/the ileum ( n =  18) or without ( n =  31) pelvic fixation were included...
June 2022: N Am Spine Soc J
https://read.qxmd.com/read/35037521/cavovarus-with-a-twist-midfoot-coronal-and-axial-plane-rotational-deformity-in-charcot-marie-tooth-disease
#16
JOURNAL ARTICLE
Tonya An, Edward Haupt, Max Michalski, Jari Salo, Glenn Pfeffer
BACKGROUND: The cavovarus deformity of Charcot-Marie-Tooth (CMT) disease is often characterized by a paradoxical relationship of hindfoot varus and forefoot valgus. The configuration of the midfoot, which links these deformities, is poorly understood. Accurate assessment of 3-dimensional alignment under physiologic loadbearing conditions is possible using weightbearing computed tomography (WBCT). This is the first study to examine the rotational deformity in the midfoot of CMT patients and, thus, provide key insights to successful correction of CMT cavovarus foot...
January 15, 2022: Foot & Ankle International
https://read.qxmd.com/read/35031852/proximal-humeral-fracture-dislocation-outcome-analysis-in-osteosynthesis-and-arthroplasties
#17
JOURNAL ARTICLE
Samuel Haupt, Sabrina Weber, Herman Frima, René Hutter, Holger Grehn, Christoph Sommer
PURPOSE: Proximal humeral fracture-dislocations (PHFD) are challenging to treat. In older patients, usually arthroplasty is performed. In younger patients, osteosynthesis is chosen. This study presents functional outcomes of these different treatment modalities. METHODS: All patients operated for PHFD from 2010 until 2017 were included. Osteosynthesis was performed in younger patients and if reconstruction was possible. Either an open deltopectoral approach or a minimal invasive plate osteosynthesis (MIPO) was performed...
January 15, 2022: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://read.qxmd.com/read/34649003/clinical-presentation-of-simple-and-combined-or-syndromic-arteriovenous-malformations
#18
JOURNAL ARTICLE
Sarah M Bernhard, Aleksandra Tuleja, Jessica E Laine, Fabian Haupt, Dario Häberli, Ulrike Hügel, Jochen Rössler, Marc Schindewolf, Iris Baumgartner
OBJECTIVE: Arteriovenous malformations of the lower extremities (AVMLE ) can present as simple or complex combined or syndromic forms (eg, Parkes Weber Syndrome). We aimed to characterize the differences in clinical presentation and natural history of these potentially life- and limb-threatening congenital vascular malformations. METHODS: We conducted a retrospective analysis of a consecutive series of patients with AVMLE who presented to a tertiary referral center in Switzerland between 2008 and 2018...
May 2022: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://read.qxmd.com/read/34155355/the-surface-topography-of-silicone-breast-implants-mediates-the-foreign-body-response-in-mice-rabbits-and-humans
#19
JOURNAL ARTICLE
Joshua C Doloff, Omid Veiseh, Roberto de Mezerville, Marcos Sforza, Tracy Ann Perry, Jennifer Haupt, Morgan Jamiel, Courtney Chambers, Amanda Nash, Samira Aghlara-Fotovat, Jessica L Stelzel, Stuart J Bauer, Sarah Y Neshat, John Hancock, Natalia Araujo Romero, Yessica Elizondo Hidalgo, Isaac Mora Leiva, Alexandre Mendonça Munhoz, Ardeshir Bayat, Brian M Kinney, H Courtney Hodges, Roberto N Miranda, Mark W Clemens, Robert Langer
Silicone is widely used in chronic implants and is generally perceived to be safe. However, textured breast implants have been associated with immune-related complications, including malignancies. Here, by examining for up to one year the foreign body response and capsular fibrosis triggered by miniaturized or full-scale clinically approved breast implants with different surface topography (average roughness, 0-90 μm) placed in the mammary fat pads of mice or rabbits, respectively, we show that surface topography mediates immune responses to the implants...
October 2021: Nature Biomedical Engineering
https://read.qxmd.com/read/33860611/a-global-approach-to-long-term-follow-up-of-targeted-and-immune-based-therapy-in-childhood-and-adolescence
#20
JOURNAL ARTICLE
Mark W Kieran, Hubert Caron, Jeanette Falck Winther, Tara O Henderson, Riccardo Haupt, Lars Hjorth, Melissa M Hudson, Leontien C M Kremer, Helena J van der Pal, Andrew D J Pearson, Leonardo Pereira, Gregory Reaman, Roderick Skinner, Gilles Vassal, Susan L Weiner, Danielle Horton Taylor
While considerable efforts and progress in our understanding of the long-term toxicities of surgery, radiation and chemotherapy in children with cancer have been made over the last 5 decades, there continues to be a wide gap in our knowledge of the long-term health impact of most novel targeted and immunotherapy agents. To address this gap, ACCELERATE, a multi-stakeholder collaboration of clinical and translational academics, regulators from the EMA and FDA, patient/family advocates and members spanning small biotechnology through to large pharmaceutical companies have initiated the development of an international long-term follow-up data registry to collect this important information prospectively...
April 16, 2021: Pediatric Blood & Cancer
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