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https://www.readbyqxmd.com/read/28646184/homing-of-cultured-endothelial-progenitor-cells-and-their-effect-on-traumatic-brain-injury-in-rat-model
#1
Xin-Bin Guo, Xin Deng, Ying Wei
Transplanted endothelial progenitor cells (EPCs) may play an important role in reestablishing the endothelial integrity of the vessels after brain injury, and contribute to neurogenesis. We, therefore, tested the homing of ex vivo cultured peripheral blood-derived EPCs and their effect on injured brain tissue after intravenous administration. To track the homing of implanted EPCs in injured brain tissues, EPCs were labeled with DAPI and BrdU in vitro before transplantation. EPCs were transplanted into the host animal through peripheral administration through the femoral vein, and homing of EPCs was evaluated...
June 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28645960/efficacy-of-adding-a-physiotherapy-rehabilitation-programme-to-arthroscopic-management-of-femoroacetabular-impingement-syndrome-a-randomised-controlled-trial-fair
#2
Kim L Bennell, Libby Spiers, Amir Takla, John O'Donnell, Jessica Kasza, David J Hunter, Rana S Hinman
OBJECTIVES: Although several rehabilitation programmes following hip arthroscopy for femoracetabular impingement (FAI) syndrome have been described, there are no clinical trials evaluating whether formal physiotherapy-prescribed rehabilitation improves recovery compared with self-directed rehabilitation. The objective of this study was to evaluate the efficacy of adding a physiotherapist-prescribed rehabilitation programme to arthroscopic surgery for FAI syndrome. DESIGN: Randomised controlled trial...
June 23, 2017: BMJ Open
https://www.readbyqxmd.com/read/28645951/effects-of-socioeconomic-factors-on-cardiovascular-related-symptoms-among-residents-in-fukushima-after-the-great-east-japan-earthquake-a-cross-sectional-study-using-data-from-the-fukushima-health-management-survey
#3
Wen Zhang, Tetsuya Ohira, Seiji Yasumura, Masaharu Maeda, Akira Otsuru, Mayumi Harigane, Naoko Horikoshi, Yuriko Suzuki, Hirooki Yabe, Masato Nagai, Hironori Nakano, Mayumi Hirosaki, Mayu Uemura, Hideto Takahashi, Kenji Kamiya, Shunichi Yamashita, Masafumi Abe
OBJECTIVE: To investigate the association between socioeconomic factors and the exacerbation of cardiovascular symptoms among evacuees after the Great East Japan Earthquake. METHODS: A sample of 73 433 individuals was included in the Fukushima Health Management Survey. Self-report questionnaires were used to determine the influence of socioeconomic factors including living arrangements, loss of employment and decreased income on the exacerbation of headache, dizziness, palpitations and shortness of breath...
June 23, 2017: BMJ Open
https://www.readbyqxmd.com/read/28645521/platelet-count-and-indoor-cold-exposure-among-elderly-people-a%C3%A2-cross-sectional-analysis-of-the-heijo-kyo-study
#4
Keigo Saeki, Kenji Obayashi, Norio Kurumatani
BACKGROUND: Excess mortality from cardiovascular disease during cold seasons is a worldwide issue. Although some physiologic studies suggests that platelet activation via cold exposure may cause an increased incidence of cardiovascular disease in winter, the influence of indoor cold exposure in real-life situations on platelet (PLT) count remains unclear. METHODS: A cross-sectional study was conducted among 1095 elderly individuals. After obtaining a venous sample in the morning, indoor temperature of participants' home was measured every 10 min for 48 h...
June 20, 2017: Journal of Epidemiology
https://www.readbyqxmd.com/read/28645278/the-impact-of-mobile-phone-based-messages-on-maternal-and-child-healthcare-behaviour-a-retrospective-cross-sectional-survey-in-bangladesh
#5
Mafruha Alam, Catherine D'Este, Cathy Banwell, Kamalini Lokuge
BACKGROUND: Mobile phones are gradually becoming an integral part of healthcare services worldwide. We assessed the association between Aponjon mobile phone based messaging services and practices regarding childbirth and care of mother and neonates in selected areas in Bangladesh. METHODS: In early 2014, 476 subscriber mothers whose last born child's age was between 3 and 18 months, were recruited to the study by Dnet from selected areas of Bangladesh. One group of mothers received the early warning messages from Aponjon during pregnancy (exposed; n = 210) while the other group of new mothers did not receive the messages during pregnancy as they had enrolled in the service after childbirth (non-exposed; n = 266)...
June 24, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28645070/passive-smoking-and-mortality-from-aortic-dissection-or-aneurysm
#6
Tomomi Kihara, Kazumasa Yamagishi, Hiroyasu Iso, Akiko Tamakoshi
BACKGROUND AND AIMS: Evidence on the association between passive smoking and risk of aortic dissection or aneurysm is limited. This study aimed to investigate whether passive smoking increases risk of mortality from aortic dissection or aneurysm. METHODS: The Japan Collaborative Cohort (JACC) Study is a prospective community-based cohort study begun in 1988-90 and followed up to the end of 2009. We examined 48,677 individuals (mean age, 56 years; women, 46%) without history of stroke, coronary heart disease, or cancer, who provided valid responses to a lifestyle questionnaire including questions on active and passive smoking...
June 9, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28645052/cardiorespiratory-responses-of-air-filtration-a-randomized-crossover-intervention-trial-in-seniors-living-in-beijing-beijing-indoor-air-purifier-study-biapsy
#7
Danqing Shao, Yipeng Du, Shuo Liu, Bert Brunekreef, Kees Meliefste, Qian Zhao, Jie Chen, Xiaoming Song, Meng Wang, Juan Wang, Hongbing Xu, Rongshan Wu, Tong Wang, Baihuan Feng, Candice Shih-Chun Lung, Xian Wang, Bei He, Wei Huang
In this Beijing Indoor Air Purifier StudY (BIAPSY), we conducted a randomized crossover intervention trial in a panel of 35 non-smoking senior participants with free-living, with and without chronic obstructive pulmonary disease (COPD). Portable air filtration units were randomly allocated to active-(filter in) for 2weeks and sham-mode (filter out) for 2weeks in the households. We examined the differences in indoor air pollutant concentrations in 20 study homes and a suite of cardio-respiratory biomarker levels in study participants between filtration modes, with and without adjustment for potential confounders...
June 20, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28644074/reinforcing-marginality-maternal-health-interventions-in-rural-nicaragua
#8
Birgit Kvernflaten
To achieve Millennium Development Goal 5 on maternal health, many countries have focused on marginalized women who lack access to care. Promoting facility-based deliveries to ensure skilled birth attendance and emergency obstetric care has become a main measure for preventing maternal deaths, so women who opt for home births are often considered 'marginal' and in need of targeted intervention. Drawing upon ethnographic data from Nicaragua, this paper critically examines the concept of marginality in the context of official efforts to increase institutional delivery amongst the rural poor, and discusses lack of access to health services among women living in peripheral areas as a process of marginalization...
June 23, 2017: Anthropology & Medicine
https://www.readbyqxmd.com/read/28643908/jaw-mechanics-in-dolichofacial-and-brachyfacial-phenotypes-a-longitudinal-cephalometric-based-study
#9
L R Iwasaki, Y Liu, H Liu, J C Nickel
OBJECTIVES: To determine whether dolichofacial (Frankfort horizontal mandibular plane angle (FHMPA) ≥30°) vs brachyfacial (FHMPA ≤22°) phenotypes differ in temporomandibular joint (TMJ) loads and whether these differences correlate longitudinally with mandibular ramus height (Condylion-Gonion, Co-Go). SETTING AND SAMPLE POPULATION: Lateral and posteroanterior cephalographs from ten dolichofacial and ten brachyfacial individuals made at average ages of 6 (T1), 12 (T2) and 18 (T3) years and available online (http://www...
June 2017: Orthodontics & Craniofacial Research
https://www.readbyqxmd.com/read/28643377/randomized-feasibility-trial-to-improve-hydroxyurea-adherence-in-youth-ages-10-18-years-through-community-health-workers-the-habit-study
#10
Nancy S Green, Deepa Manwani, Sergio Matos, April Hicks, Luisa Soto, Yina Castillo, Karen Ireland, Yvonne Stennett, Sally Findley, Haomiao Jia, Arlene Smaldone
INTRODUCTION: The main therapeutic intervention for sickle cell disease (SCD) is hydroxyurea (HU). The effect of HU is largely through dose-dependent induction of fetal hemoglobin (HbF). Poor HU adherence is common among adolescents. METHODS: Our 6-month, two-site pilot intervention trial, "HABIT," was led by culturally aligned community health workers (CHWs). CHWs performed support primarily through home visits, augmented by tailored text message reminders. Dyads of youth with SCD ages 10-18 years and a parent were enrolled...
June 23, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28643119/home-based-versus-center-based-aerobic-exercise-on-cardiopulmonary-performance-physical-function-quality-of-life-and-quality-of-sleep-of-overweight-patients-with-chronic-kidney-disease
#11
Danilo Takashi Aoike, Flavia Baria, Maria Ayako Kamimura, Adriano Ammirati, Lilian Cuppari
BACKGROUND: The association between chronic kidney disease (CKD) and obesity can decrease the patients' cardiopulmonary capacity, physical functioning and quality of life. The search for effective and practical alternative methods of exercise to engage patients in training programs is of great importance. Therefore, we aimed to compare the effects of home-based versus center-based aerobic exercise on the cardiopulmonary and functional capacities, quality of life and quality of sleep of overweight non-dialysis-dependent patients with CKD (NDD-CKD)...
June 22, 2017: Clinical and Experimental Nephrology
https://www.readbyqxmd.com/read/28642372/the-highland-health-advocates-a-preliminary-evaluation-of-a-novel-programme-addressing-the-social-needs-of-emergency-department-patients
#12
Lia Ilona Losonczy, Dennis Hsieh, Michael Wang, Christopher Hahn, Tarak Trivedi, Marcela Rodriguez, Jahan Fahimi, Harrison Alter
OBJECTIVES: Patients commonly come to the emergency department (ED) with social needs. To address this, we created the Highland Health Advocates (HHA), an ED-based help desk and medical-legal partnership using undergraduate volunteers to help patients navigate public resources and provide onsite legal and social work referrals. We were able to provide these services in English and Spanish. We aimed to determine the social needs of the patients who presented to our ED and the potential impact of the programme in resolving those needs and connecting them to a 'medical home' (defined as a consistent, primary source of medical care such as a primary care doctor or clinic)...
June 22, 2017: Emergency Medicine Journal: EMJ
https://www.readbyqxmd.com/read/28642333/patients-and-providers-perceptions-of-the-preventability-of-hospital-readmission-a-prospective-observational-study-in-four-european-countries
#13
Louise S van Galen, Mikkel Brabrand, Tim Cooksley, Peter M van de Ven, Hanneke Merten, Ralph Kl So, Loes van Hooff, Harm R Haak, Rachel M Kidney, Christian H Nickel, John Ty Soong, Immo Weichert, Mark Hh Kramer, Christian P Subbe, Prabath Wb Nanayakkara
OBJECTIVES: Because of fundamental differences in healthcare systems, US readmission data cannot be extrapolated to the European setting: To investigate the opinions of readmitted patients, their carers, nurses and physicians on predictability and preventability of readmissions and using majority consensus to determine contributing factors that could potentially foresee (preventable) readmissions. DESIGN: Prospective observational study. Readmitted patients, their carers, and treating professionals were surveyed during readmission to assess the discharge process and the predictability and preventability of the readmission...
June 22, 2017: BMJ Quality & Safety
https://www.readbyqxmd.com/read/28642068/chloramphenicol-decreases-cb1-receptor-expression-in-the-nucleus-accumbens-and-prefrontal-cortex-and-prevents-amphetamine-induced-conditioned-place-preference-in-rats
#14
Octavio Amancio-Belmont, Diego Pérez-Vázquez, Alejandra E Ruiz-Contreras, Miguel Pérez de la Mora, Pavel E Rueda-Orozco, Mónica Méndez-Díaz, Oscar E Prospero-Garcia
Drug dependence seems to involve a learning and memory process. Since learning and memory depend on protein synthesis, drug dependence may depend on protein synthesis, too. Drug-induced reward is a crucial effect for the development of drug-dependence. We used chloramphenicol (CAP, a protein synthesis inhibitor), to evaluate its effects on amphetamine (amph)-seeking behavior, on CB1R expression and on protein synthesis in general, in specific areas of the brain. Two groups of Wistar adult male rats were subjected to amph-induced conditioned place preference (CPP)...
June 19, 2017: Pharmacology, Biochemistry, and Behavior
https://www.readbyqxmd.com/read/28641599/association-between-level-of-exposure-to-death-and-dying-and-professional-quality-of-life-among-palliative-care-workers
#15
Tali Samson, Pesach Shvartzman
BACKGROUND: Exposure to the death and dying of others is an anxiety-provoking condition that can contribute to psychological stress. However, the results of empirical studies that evaluated work-related outcomes among physicians and nurses with repeated exposure to dying patients are not consistent. OBJECTIVE: Our aim was to evaluate whether a high level of exposure to death and dying (LED) can increase the risk for poor professional quality of life (ProQoL) in most healthcare workers, but it can also improve ProQoL in a subset of healthcare workers with specific characteristics...
June 23, 2017: Palliative & Supportive Care
https://www.readbyqxmd.com/read/28641166/care-coordination-at-a-pediatric-accountable-care-organization-aco-a-qualitative-analysis
#16
Baria Hafeez, Sophia Miller, Anup D Patel, Zachary M Grinspan
OBJECTIVE: Care coordinators may help manage care for children with chronic illness. Their role in pediatric epilepsy care is understudied. We aimed to qualitatively describe the content of a care coordination intervention for children with epilepsy. METHODS: We conducted nine semi-structured interviews and one focus group with care coordinators at a pediatric accountable care organization (ACO) in Ohio. The care coordinators used a modified version of a published care coordination checklist for children with epilepsy (Patel AD, 2014)...
June 19, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28640845/is-self-assessment-of-medical-abortion-using-a-low-sensitivity-pregnancy-test-combined-with-a-checklist-and-phone-text-messages-feasible-in-south-african-primary-healthcare-settings-a-randomized-trial
#17
Deborah Constant, Jane Harries, Kristen Daskilewicz, Landon Myer, Kristina Gemzell-Danielsson
OBJECTIVE: To evaluate feasibility of self-assessment of medical abortion outcome using a low-sensitivity urine pregnancy test, checklist and text messages. The study assessed whether accurate self-assessment required a demonstration of the low-sensitivity urine pregnancy test or if verbal instructions suffice. METHODS: This non-inferiority trial enrolled 525 adult women from six public sector abortion clinics. Eligible women were undergoing medical abortion at gestations within 63 days...
2017: PloS One
https://www.readbyqxmd.com/read/28640674/racial-ethnic-minority-older-adults-perspectives-on-proposed-medicaid-reforms-effects-on-dental-care-access
#18
Mary E Northridge, Ivette Estrada, Eric W Schrimshaw, Ariel P Greenblatt, Sara S Metcalf, Carol Kunzel
To examine how proposed Medicaid reform plans are experienced by racial/ethnic minority older adults and what the implications are for their ability to access dental care through Medicaid, from 2013 to 2015 we conducted focus groups in northern Manhattan, New York, New York, among African American, Dominican, and Puerto Rican adults aged 50 years and older. Participants reported problems with affording copayments for care, complicated health and social issues, the need for vision and dental care close to home, and confusion about and stigmatization with Medicaid coverage...
June 22, 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28640509/meeting-the-needs-of-critical-care-patients-after-discharge-home-a-qualitative-exploratory-study-of-patient-perspectives
#19
Laura Allum, Bronwen Connolly, Eamonn McKeown
BACKGROUND: With improved survival rates in critical care, increasing focus is being placed on survivorship and how best to support patients in returning to their former activity. Little is known about what support patients themselves view as important, and this has implications for the efficacy and acceptability of services provided. OBJECTIVES: To describe former critical care patients' perspectives on the support needed to optimize recovery. STUDY DESIGN: This is a qualitative exploratory study of the experiences of support received by critical care survivors...
June 22, 2017: Nursing in Critical Care
https://www.readbyqxmd.com/read/28639869/economic-burden-of-inpatient-admission-of-ankle-fractures
#20
Justin D Stull, Suneel B Bhat, Justin M Kane, Steven M Raikin
BACKGROUND: Ankle fractures are among the most prevalent traumatic orthopaedic injuries. A large proportion of patients sustaining operative ankle fractures are admitted directly from the emergency department prior to operative management. In the authors' experience, however, many closed ankle injuries may be safely and effectively managed on an outpatient basis. The aim of this study was to characterize the economic impact of routine inpatient admission of ankle fractures. METHODS: A retrospective review of all outpatient ankle fracture surgery performed by a single foot and ankle fellowship-trained surgeon at a tertiary level academic center in 2012 was conducted to identify any patients requiring postoperative inpatient admission...
June 1, 2017: Foot & Ankle International
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