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https://www.readbyqxmd.com/read/28205058/gastric-cancer-treated-by-endoscopic-submucosal-dissection-or-endoscopic-mucosal-resection-in-japan-from-2004-through-2006-jgca-nationwide-registry-conducted-in-2013
#1
Satoshi Tanabe, Shigeki Hirabayashi, Ichiro Oda, Hiroyuki Ono, Atsushi Nashimoto, Yoh Isobe, Isao Miyashiro, Shunichi Tsujitani, Yasuyuki Seto, Takeo Fukagawa, Souya Nunobe, Hiroshi Furukawa, Yasuhiro Kodera, Michio Kaminishi, Hitoshi Katai
BACKGROUND: The Japanese Gastric Cancer Association (JGCA) initiated a new nationwide gastric cancer registry in 2008 and reported the treatment outcomes of patients with primary gastric cancer who underwent surgical therapy in 2001 and 2003. However, the outcomes of endoscopic therapy have not been reported yet. METHODS: The JGCA conducted a retrospective nationwide registry in 2013 to investigate the short-term and long-term outcomes of endoscopic mucosal resection or endoscopic submucosal dissection in patients with gastric cancer treated from January 2004 through December 2006...
February 15, 2017: Gastric Cancer
https://www.readbyqxmd.com/read/28133197/-a-case-of-early-onset-rapidly-progressive-cerebral-infarction-with-trousseau-s-syndrome-in-a-patient-with-pancreatic-cancer-undergoing-surgery
#2
Norikazu Yogi, Hiroyuki Nojima, Hiroaki Shimizu, Masayuki Ohtsuka, Atsushi Kato, Hideyuki Yoshitomi, Katsunori Furukawa, Tsukasa Takayashiki, Shigetsugu Takano, Satoshi Kuboki, Daisuke Suzuki, Nozomu Sakai, Shingo Kagawa, Masaru Miyazaki
Trousseau's syndrome refers to cerebral infarction associated with hypercoagulability caused by cancer. Here, we report a case of Trousseau's syndrome in a patient with pancreatic cancer undergoing surgery. A 71-year-old woman was diagnosed with pancreatic head cancer with portal vein invasion; she underwent pancreaticoduodenectomy combined with portal vein resection. Pathological examination showed poorly differentiated adenocarcinoma with para-aortic lymph nodal metastasis. Although the patient had an uneventful postoperative course, she suddenly developed right hemiplegia and dysarthria 6 weeks after surgery, resulting in multiple cerebral infarctions scattered over both hemispheres...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28133192/-a-radically-resected-case-of-ruptured-ipmc-of-the-pancreas-after-abscess-drainage-using-an-endoscopic-naso-pancreatic-drainage-tube
#3
Arata Furukawa, Satoshi Kuboki, Hiroaki Shimizu, Masayuki Ohtsuka, Hideyuki Yoshitomi, Katsunori Furukawa, Tsukasa Takayashiki, Shigetsugu Takano, Daisuke Suzuki, Nozomu Sakai, Shingo Kagawa, Hiroyuki Nojima, Masaru Miyazaki
A 79-year-old man was referred to our hospital because of sudden upper abdominal pain. Enhanced computed tomography revealed a huge multilocular cystic tumor with a thickened wall, which was connected with the main pancreatic duct of the pancreatic body. Abscess formation was seen inside the omental bursa; however, there were no signs of direct invasion of the cystic tumor into the stomach or transverse colon. Therefore, we performed emergency endoscopic naso-pancreatic drainage(ENPD)under the diagnosis of an intraperitoneal abscess caused by rupture of intraductal papillary mucinous carcinoma(IPMC)...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28133133/-a-rare-complication-of-transcatheter-arterial-injection-for-multiple-liver-metastases-of-rectal-neuroendocrine-tumor-a-case-report
#4
Kensuke Suzuki, Nozomu Sakai, Hiroaki Shimizu, Masayuki Ohtsuka, Hideyuki Yoshitomi, Katsunori Furukawa, Tsukasa Takayashiki, Satoshi Kuboki, Shigetsugu Takano, Daisuke Suzuki, Shingo Kagawa, Hiroyuki Nojima, Masaru Miyazaki
A 50-year-old man was diagnosed with multiple bilobar liver metastases of rectal neuroendocrine tumor(NET). Although he received octreotide for 6 months and everolimus for 10 months, the liver metastases gradually increased in size. Therefore, we decided to perform transcatheter arterial infusion(TAI)with miriplatin. The serum total bilirubin level increased to 13.1 mg/dL 9 days after treatment, and it took 2 months to return to the normal range. CT scan demonstrated that most of the liver tumors had remarkably shrunk 4 months after treatment, and the patient has no sign of tumor regrowth even 12 months after treatment...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28133092/-two-cases-of-remnant-pancreatic-cancer-treated-using-remnant-pancreatectomy-combined-with-hepatic-arterial-resection
#5
Atsuhiko Ueda, Nozomu Sakai, Hideyuki Yoshitomi, Hiroaki Shimizu, Masayuki Ohtsuka, Atsushi Kato, Katsunori Furukawa, Tsukasa Takayashiki, Shigetsugu Takano, Satoshi Kuboki, Daisuke Suzuki, Shingo Kagawa, Hiroyuki Nojima, Masaru Miyazaki
Case 1: A 40-year-old man was diagnosed with remnant pancreatic cancer invading the celiac axis 8 months after pancreaticoduodenectomy for pancreatic head cancer. As his gastroduodenal artery had been resected, the patient underwent preoperative coil embolization of the common hepatic artery for the development of extrahepatic collaterals. Eighteen days after the coil embolization, remnant pancreatectomy combined with celiac axis resection without reconstruction was performed. The patient was discharged without postoperative hepatic complications...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28069106/portal-vein-thrombosis-after-reconstruction-in-270-consecutive-patients-with-portal-vein-resections-in-hepatopancreatobiliary-hpb-surgery
#6
Masaru Miyazaki, Hiroaki Shimizu, Masayuki Ohtuka, Atsushi Kato, Hiroyuki Yoshitomi, Katsunori Furukawa, Tsukasa Takayashiki, Satoshi Kuboki, Shigetsugu Takano, Daisuke Suzuki, Taku Higashihara
BACKGROUNDS: This study was aimed to evaluate the occurrence of portal vein thrombosis after portal vein reconstruction. METHODS: The portal veins were repaired with venorrhaphy, end-to-end, patch graft, and segmental graft in consecutive 270 patients undergoing hepato-pancreto-biliary (HPB) surgery. RESULTS: Portal vein thrombosis was encountered in 20 of 163 of end-to-end, 2 of 56 of venorrhaphy, and 2 of 5 of patch graft groups, as compared with 0 of 46 of segmental graft group (p < 0...
December 24, 2016: American Journal of Surgery
https://www.readbyqxmd.com/read/27849659/a-new-proposal-of-criteria-for-the-future-remnant-liver-volume-in-older-patients-undergoing-major-hepatectomy-for-biliary-tract-cancer
#7
Yoshihiro Watanabe, Satoshi Kuboki, Hiroaki Shimizu, Masayuki Ohtsuka, Hideyuki Yoshitomi, Katsunori Furukawa, Masaru Miyazaki
OBJECTIVE: To evaluate whether advanced age increases the risk of severe complications after major hepatectomy with bile duct resection (BDR) in patients with biliary tract cancer, and to establish new criteria for the percentage of the future remnant liver volume (%FLV) in older patients undergoing this operation. BACKGROUND: Advanced age is reported to inhibit liver regeneration and suppress immune function; however, little is known about the risk of aging in high-stress surgery, such as biliary tract surgery...
November 15, 2016: Annals of Surgery
https://www.readbyqxmd.com/read/26805378/-surgical-resection-of-metachronous-hepatic-metastasis-from-pancreatic-acinar-cell-carcinoma-after-total-pancreatectomy
#8
REVIEW
Takashi Mishima, Katsunori Furukawa, Hiroaki Shimizu, Masayuki Ohtsuka, Atsushi Kato, Hideyuki Yoshitomi, Tsukasa Takayashiki, Satoshi Kuboki, Shigeaki Takano, Daiki Okamura, Daisuke Suzuki, Nozomu Sakai, Shingo Kagawa, Masaru Miyazaki
Pancreatic acinar cell carcinoma is rare. There is no consensus on a treatment strategy for metastatic lesions to the liver. We report of a 68-year-old man who received total pancreatectomy for pancreatic acinar cell carcinoma. One year after surgery, abdominal enhanced CT showed a small liver tumor in segment 8. We diagnosed this tumor as hepatic metastasis of pancreatic acinar cell carcinoma, and we resected it via partial liver resection. Pathological studies indicated a metastasis from pancreatic acinar cell carcinoma...
November 2015: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/26805371/-a-case-of-r0-resection-of-locally-advanced-pancreatic-cancer-following-chemoradiation-therapy
#9
Yoji Miyahara, Daiki Okamura, Takahiro Nishida, Hiroaki Shimizu, Masayuki Ohtsuka, Atsushi Kato, Hideyuki Yoshitomi, Katsunori Furukawa, Tsukasa Takayashiki, Satoshi Kuboki, Shigetsugu Takano, Daisuke Suzuki, Nozomu Sakai, Shingo Kagawa, Masaru Miyazaki
Patients with borderline resectable pancreatic cancer have a poorer prognosis than patients with resectable pancreatic cancer, but some cases treated with neoadjuvant chemoradiation therapy and radical surgery (R0 surgery) show long-term survival. A 72-year-old woman presented with a history of back pain and weight loss. Computed tomography revealed a cancer of the pancreatic body encasing the celiac trunk, common hepatic artery, and portal vein. After neoadjuvant chemotherapy ( S-1) and carbon-ion radiotherapy, the tumor was considered to be resectable...
November 2015: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/26805092/-peritoneovenous-shunting-as-a-palliative-therapy-for-refractory-ascites-after-biliary-cancer-surgery
#10
Youhei Miyauchi, Tsukasa Takayashiki, Hiroaki Shimizu, Masayuki Ohtsuka, Atsushi Kato, Hideyuki Yoshitomi, Katsunori Furukawa, Shigetsugu Takano, Satoshi Kuboki, Daisuke Suzuki, Nozomu Sakai, Shingo Kagawa, Hiroyuki Nojima, Masaru Miyazaki
The quality of life of patients with recurrence of biliary cancer is remarkably diminished by the occurrence of refractory ascites caused by peritoneal dissemination or portal vein obstruction. In this study, we examined the effectiveness of peritoneovenous shunting (PVS) in patients with refractory ascites after recurrence of biliary cancer. PVS was performed 7 times in 5 patients, with 6 shunts (85.7%) placed from the left-side abdomen to the left subclavian vein. During the median observation period of 136 days, the ascites and symptoms of abdominal distension disappeared in 4 patients...
November 2015: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/26569206/auraptene-acts-as-an-anti-inflammatory-agent-in-the-mouse-brain
#11
Satoshi Okuyama, Mayu Morita, Miki Kaji, Yoshiaki Amakura, Morio Yoshimura, Koji Shimamoto, Yu Ookido, Mitsunari Nakajima, Yoshiko Furukawa
The anti-inflammatory activity of auraptene (AUR), a citrus coumarin, in peripheral tissues is well-known, and we previously demonstrated that AUR exerts anti-inflammatory effects in the ischemic brain; the treatment of mice with AUR for eight days immediately after ischemic surgery suppressed demise and neuronal cell death in the hippocampus, possibly through its anti-inflammatory effects in the brain. We suggested that these effects were at least partly mediated by the suppression of inflammatory mediators derived from astrocytes...
2015: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/25972515/clinical-efficacy-of-daikenchuto-for-gastrointestinal-dysfunction-following-colon-surgery-a-randomized-double-blind-multicenter-placebo-controlled-study-jfmc39-0902
#12
RANDOMIZED CONTROLLED TRIAL
Hidetoshi Katsuno, Koutarou Maeda, Takashi Kaiho, Katsuyuki Kunieda, Kimihiko Funahashi, Junichi Sakamoto, Toru Kono, Hirotoshi Hasegawa, Yoshiyuki Furukawa, Yoshihiro Imazu, Satoshi Morita, Masahiko Watanabe
OBJECTIVE: This exploratory trial was performed to determine whether Daikenchuto accelerates recovery of gastrointestinal function in patients undergoing open colectomy for colon cancer. METHODS: A total of 386 patients undergoing colectomy at 1 of the 51 clinical trial sites in Japan from January 2009 to June 2011 were registered for the study (JFMC39-0902). Patients received either placebo or Daikenchuto (15.0 g/day, t.i.d) between post-operative day 2 and post-operative day 8...
July 2015: Japanese Journal of Clinical Oncology
https://www.readbyqxmd.com/read/25732615/sclerosing-stromal-tumor-of-the-ovary-treated-with-2-incision-total-laparoscopic-cystectomy
#13
Shigenori Furukawa, Kiyoshi Kanno, Manabu Kojima, Miki Ohara, Shu Soeda, Satoshi Suzuki, Takafumi Watanabe, Hiroshi Nishiyama, Tsuyoshi Honda, Keiya Fujimori
Sclerosing stromal tumor (SST) is an extremely rare benign tumor of the ovary that is derived from the sex cord stroma [1,2] and occurs in young women [3-11]. Preoperative diagnosis of the tumor is difficult as it often mimics a malignant tumor. Oophorectomy is usually performed in many cases of young women [3], and diagnosis of SST is made based on post-operative pathological examination. Laparoscopic surgery is seldom performed in SST cases. Here, we report a case of SST of the ovary in an 18-year-old girl who was diagnosed by preoperative imaging and underwent laparoscopic cystectomy...
2015: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/25731235/-a-case-of-curative-resection-after-downsizing-chemotherapy-in-initially-unresectable-locally-advanced-intrahepatic-cholangiocarcinoma
#14
Yu Aoki, Takayuki Suzuki, Atsushi Kato, Hiroaki Shimizu, Masayuki Ohtsuka, Hideyuki Yoshitomi, Katsunori Furukawa, Tsukasa Takayashiki, Satoshi Kuboki, Shigetsugu Takano, Daiki Okamura, Daisuke Suzuki, Nozomu Sakai, Shingo Kagawa, Masaru Miyazaki
This case report describes an 83-year-old man with intrahepatic cholangiocarcinoma who was referred by a local hospital. Abdominal computed tomography (CT) showed a large tumor in hepatic segments 4, 5, and 8 involving the right hepatic vein and inferior vena cava, which is normally indicative of an unresectable locally advanced tumor. After systemic chemotherapy with gemcitabine and cisplatin, the observed decrease in the level of tumor marker suggested that the cancer was responding to treatment, while radiological findings showed the main tumor shrunk without the presence of distant metastases...
November 2014: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/25614490/partial-nephrectomy-for-hilar-tumors-comparison-of-conventional-open-and-robot-assisted-approaches
#15
COMPARATIVE STUDY
Hideaki Miyake, Nobuyuki Hinata, Satoshi Imai, Junya Furukawa, Kazushi Tanaka, Masato Fujisawa
BACKGROUND: To characterize clinical advantages in robot-assisted partial nephrectomy (RAPN) for targeting renal hilar tumors, and compare them with those of open PN (OPN). METHODS: This study included 31 consecutive patients with renal hilar tumors, consisting of 15 and 16 who received OPN and RAPN, respectively, between January 2012 and May 2014. The perioperative and oncological outcomes of the two approaches were compared. In this series, a hilar tumor was defined as a renal cortical tumor located in the renal hilum that was shown, by preoperative imaging, to be in direct physical contact with the renal artery and/or vein...
August 2015: International Journal of Clinical Oncology
https://www.readbyqxmd.com/read/25410442/efficacy-of-2-port-laparoscopic-surgery-for-gynecologic-disease-invention-of-new-suture-technique
#16
COMPARATIVE STUDY
Satoshi Suzuki, Shigenori Furukawa, Miki Ohara, Kiyoshi Kanno, Shun Yasuda, Takeharu Ohzeki, Takafumi Watanabe, Hidenori Takahashi, Hiroshi Suzuki, Keiya Fujimori
BACKGROUND AND OBJECTIVE: To evaluate the efficacy and safety of 2-port laparoscopic surgery for ovarian tumors and uterine leiomyomas. A conventional slip knot under laparoscopic surgery is useful, but it is difficult for beginners. Therefore, we developed new suture technique. METHODS: Between January 2011 and December 2012, 38 patients underwent 2-port total laparoscopic cystectomy (TLC); between January 2010 and December 2011, 45 patients underwent multiport (3 or 4 ports) TLC...
2014: Fukushima Journal of Medical Science
https://www.readbyqxmd.com/read/25390978/cytomegalovirus-retinitis-after-intravitreous-triamcinolone-treatment-of-a-vitrectomized-eye-in-an-immunocompetent-patient
#17
Mariko Furukawa, Kazuyuki Kumagai, Nobuchika Ogino, Satoshi Okinami, Akinori Uemura, Eric Larson
PURPOSE: To report a case of cytomegalovirus (CMV) retinitis after intravitreous injection of triamcinolone for a vitrectomized eye in an immunocompetent patient. DESIGN: Observational case report. METHODS: Review of medical records. RESULTS: A 54-year-old woman with well-controlled type 2 diabetes developed anterior uveitis, papillitis, retinal vasculitis, and retinal exudates 3 months after intravitreous triamcinolone for the treatment of recurred macular edema...
2007: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/25074253/incidence-and-outcome-of-surgical-procedures-after-coronary-artery-bypass-grafting-compared-with-those-after-percutaneous-coronary-intervention-a-report-from-the-coronary-revascularization-demonstrating-outcome-study-in-kyoto-pci-cabg-registry-cohort-2
#18
MULTICENTER STUDY
Akihiro Tokushige, Hiroki Shiomi, Takeshi Morimoto, Koh Ono, Yutaka Furukawa, Yoshihisa Nakagawa, Kazushige Kadota, Kenji Ando, Satoshi Shizuta, Tomohisa Tada, Junichi Tazaki, Yoshihiro Kato, Mamoru Hayano, Mitsuru Abe, Shuichi Hamasaki, Mitsuru Ohishi, Hitoshi Nakashima, Kazuaki Mitsudo, Masakiyo Nobuyoshi, Toru Kita, Yutaka Imoto, Ryuzo Sakata, Hitoshi Okabayashi, Michiya Hanyu, Mitsuomi Shimamoto, Noboru Nishiwaki, Tatsuhiko Komiya, Takeshi Kimura
BACKGROUND: Noncardiac surgery after percutaneous coronary intervention (PCI) has been reported to be carrying high risk for both ischemic and bleeding complications. However, there has been no report comparing the incidence and outcomes of surgical procedures after coronary artery bypass grafting (CABG) with those after PCI. METHODS AND RESULTS: Among 14 383 patients undergoing first coronary revascularization (PCI, n=12 207; CABG, n=2176) enrolled in the Coronary Revascularization Demonstrating Outcome Study in Kyoto (CREDO-Kyoto) PCI/CABG Registry Cohort-2, surgical procedures were performed more frequently after CABG (n=560) than after PCI (n=2398; cumulative 3-year incidence: 27% versus 22%; unadjusted P<0...
August 2014: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/24657445/3-5-6-7-8-3-4-heptamethoxyflavone-a-citrus-flavonoid-on-protection-against-memory-impairment-and-neuronal-cell-death-in-a-global-cerebral-ischemia-mouse-model
#19
Satoshi Okuyama, Mayu Morita, Kazuhiro Miyoshi, Yuki Nishigawa, Miki Kaji, Atsushi Sawamoto, Tsukasa Terugo, Nobuki Toyoda, Nahomi Makihata, Yoshiaki Amakura, Morio Yoshimura, Mitsunari Nakajima, Yoshiko Furukawa
The present study evaluated the effects of treatment with the citrus flavonoid, 3,5,6,7,8,3',4'-heptamethoxyflavone (HMF) on protection against memory impairment and neuronal death in a global cerebral ischemia mouse model. The results showed that HMF, administrated for three days immediately after ischemic surgery, protected against ischemia-induced memory dysfunction, rescued neuronal cell death in the CA1 cell layer, increased the production of BDNF, stimulated the autophosphorylation of CaMK II and suppressed microglial activation in the hippocampus...
May 2014: Neurochemistry International
https://www.readbyqxmd.com/read/24256464/improvement-of-long-term-outcomes-in-pancreatic-cancer-and-its-associated-factors-within-the-gemcitabine-era-a-collaborative-retrospective-multicenter-clinical-review-of-1-082-patients
#20
MULTICENTER STUDY
Taira Kuroda, Teru Kumagi, Tomoyuki Yokota, Hirotaka Seike, Mari Nishiyama, Yusuke Imai, Nobu Inada, Naozumi Shibata, Satoshi Imamine, Shin-ichi Okada, Mitsuhito Koizumi, Hirofumi Yamanishi, Nobuaki Azemoto, Jiro Miyaike, Yoshinori Tanaka, Haruka Tatsukawa, Hiroki Utsunomiya, Yoshinori Ohno, Teruki Miyake, Masashi Hirooka, Shinya Furukawa, Masanori Abe, Yoshiou Ikeda, Bunzo Matsuura, Yoichi Hiasa, Morikazu Onji
BACKGROUND: Although the outcomes of pancreatic cancer have been improved by gemcitabine, the changes in its characteristics and long-term outcomes within the gemcitabine era remain unclear. This study was conducted to identify clinical characteristics of pancreatic cancer patients within the gemcitabine era. METHODS: A retrospective chart review was performed at 10 centers for 1,248 consecutive patients who were ever considered to have a diagnosis of pancreatic cancer between 2001 and 2010...
2013: BMC Gastroenterology
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