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https://www.readbyqxmd.com/read/27849659/a-new-proposal-of-criteria-for-the-future-remnant-liver-volume-in-older-patients-undergoing-major-hepatectomy-for-biliary-tract-cancer
#1
Yoshihiro Watanabe, Satoshi Kuboki, Hiroaki Shimizu, Masayuki Ohtsuka, Hideyuki Yoshitomi, Katsunori Furukawa, Masaru Miyazaki
OBJECTIVE: To evaluate whether advanced age increases the risk of severe complications after major hepatectomy with bile duct resection (BDR) in patients with biliary tract cancer, and to establish new criteria for the percentage of the future remnant liver volume (%FLV) in older patients undergoing this operation. BACKGROUND: Advanced age is reported to inhibit liver regeneration and suppress immune function; however, little is known about the risk of aging in high-stress surgery, such as biliary tract surgery...
November 15, 2016: Annals of Surgery
https://www.readbyqxmd.com/read/26805378/-surgical-resection-of-metachronous-hepatic-metastasis-from-pancreatic-acinar-cell-carcinoma-after-total-pancreatectomy
#2
REVIEW
Takashi Mishima, Katsunori Furukawa, Hiroaki Shimizu, Masayuki Ohtsuka, Atsushi Kato, Hideyuki Yoshitomi, Tsukasa Takayashiki, Satoshi Kuboki, Shigeaki Takano, Daiki Okamura, Daisuke Suzuki, Nozomu Sakai, Shingo Kagawa, Masaru Miyazaki
Pancreatic acinar cell carcinoma is rare. There is no consensus on a treatment strategy for metastatic lesions to the liver. We report of a 68-year-old man who received total pancreatectomy for pancreatic acinar cell carcinoma. One year after surgery, abdominal enhanced CT showed a small liver tumor in segment 8. We diagnosed this tumor as hepatic metastasis of pancreatic acinar cell carcinoma, and we resected it via partial liver resection. Pathological studies indicated a metastasis from pancreatic acinar cell carcinoma...
November 2015: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/26805371/-a-case-of-r0-resection-of-locally-advanced-pancreatic-cancer-following-chemoradiation-therapy
#3
Yoji Miyahara, Daiki Okamura, Takahiro Nishida, Hiroaki Shimizu, Masayuki Ohtsuka, Atsushi Kato, Hideyuki Yoshitomi, Katsunori Furukawa, Tsukasa Takayashiki, Satoshi Kuboki, Shigetsugu Takano, Daisuke Suzuki, Nozomu Sakai, Shingo Kagawa, Masaru Miyazaki
Patients with borderline resectable pancreatic cancer have a poorer prognosis than patients with resectable pancreatic cancer, but some cases treated with neoadjuvant chemoradiation therapy and radical surgery (R0 surgery) show long-term survival. A 72-year-old woman presented with a history of back pain and weight loss. Computed tomography revealed a cancer of the pancreatic body encasing the celiac trunk, common hepatic artery, and portal vein. After neoadjuvant chemotherapy ( S-1) and carbon-ion radiotherapy, the tumor was considered to be resectable...
November 2015: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/26805092/-peritoneovenous-shunting-as-a-palliative-therapy-for-refractory-ascites-after-biliary-cancer-surgery
#4
Youhei Miyauchi, Tsukasa Takayashiki, Hiroaki Shimizu, Masayuki Ohtsuka, Atsushi Kato, Hideyuki Yoshitomi, Katsunori Furukawa, Shigetsugu Takano, Satoshi Kuboki, Daisuke Suzuki, Nozomu Sakai, Shingo Kagawa, Hiroyuki Nojima, Masaru Miyazaki
The quality of life of patients with recurrence of biliary cancer is remarkably diminished by the occurrence of refractory ascites caused by peritoneal dissemination or portal vein obstruction. In this study, we examined the effectiveness of peritoneovenous shunting (PVS) in patients with refractory ascites after recurrence of biliary cancer. PVS was performed 7 times in 5 patients, with 6 shunts (85.7%) placed from the left-side abdomen to the left subclavian vein. During the median observation period of 136 days, the ascites and symptoms of abdominal distension disappeared in 4 patients...
November 2015: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/26569206/auraptene-acts-as-an-anti-inflammatory-agent-in-the-mouse-brain
#5
Satoshi Okuyama, Mayu Morita, Miki Kaji, Yoshiaki Amakura, Morio Yoshimura, Koji Shimamoto, Yu Ookido, Mitsunari Nakajima, Yoshiko Furukawa
The anti-inflammatory activity of auraptene (AUR), a citrus coumarin, in peripheral tissues is well-known, and we previously demonstrated that AUR exerts anti-inflammatory effects in the ischemic brain; the treatment of mice with AUR for eight days immediately after ischemic surgery suppressed demise and neuronal cell death in the hippocampus, possibly through its anti-inflammatory effects in the brain. We suggested that these effects were at least partly mediated by the suppression of inflammatory mediators derived from astrocytes...
2015: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/25972515/clinical-efficacy-of-daikenchuto-for-gastrointestinal-dysfunction-following-colon-surgery-a-randomized-double-blind-multicenter-placebo-controlled-study-jfmc39-0902
#6
RANDOMIZED CONTROLLED TRIAL
Hidetoshi Katsuno, Koutarou Maeda, Takashi Kaiho, Katsuyuki Kunieda, Kimihiko Funahashi, Junichi Sakamoto, Toru Kono, Hirotoshi Hasegawa, Yoshiyuki Furukawa, Yoshihiro Imazu, Satoshi Morita, Masahiko Watanabe
OBJECTIVE: This exploratory trial was performed to determine whether Daikenchuto accelerates recovery of gastrointestinal function in patients undergoing open colectomy for colon cancer. METHODS: A total of 386 patients undergoing colectomy at 1 of the 51 clinical trial sites in Japan from January 2009 to June 2011 were registered for the study (JFMC39-0902). Patients received either placebo or Daikenchuto (15.0 g/day, t.i.d) between post-operative day 2 and post-operative day 8...
July 2015: Japanese Journal of Clinical Oncology
https://www.readbyqxmd.com/read/25732615/sclerosing-stromal-tumor-of-the-ovary-treated-with-2-incision-total-laparoscopic-cystectomy
#7
Shigenori Furukawa, Kiyoshi Kanno, Manabu Kojima, Miki Ohara, Shu Soeda, Satoshi Suzuki, Takafumi Watanabe, Hiroshi Nishiyama, Tsuyoshi Honda, Keiya Fujimori
Sclerosing stromal tumor (SST) is an extremely rare benign tumor of the ovary that is derived from the sex cord stroma [1,2] and occurs in young women [3-11]. Preoperative diagnosis of the tumor is difficult as it often mimics a malignant tumor. Oophorectomy is usually performed in many cases of young women [3], and diagnosis of SST is made based on post-operative pathological examination. Laparoscopic surgery is seldom performed in SST cases. Here, we report a case of SST of the ovary in an 18-year-old girl who was diagnosed by preoperative imaging and underwent laparoscopic cystectomy...
2015: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/25731235/-a-case-of-curative-resection-after-downsizing-chemotherapy-in-initially-unresectable-locally-advanced-intrahepatic-cholangiocarcinoma
#8
Yu Aoki, Takayuki Suzuki, Atsushi Kato, Hiroaki Shimizu, Masayuki Ohtsuka, Hideyuki Yoshitomi, Katsunori Furukawa, Tsukasa Takayashiki, Satoshi Kuboki, Shigetsugu Takano, Daiki Okamura, Daisuke Suzuki, Nozomu Sakai, Shingo Kagawa, Masaru Miyazaki
This case report describes an 83-year-old man with intrahepatic cholangiocarcinoma who was referred by a local hospital. Abdominal computed tomography (CT) showed a large tumor in hepatic segments 4, 5, and 8 involving the right hepatic vein and inferior vena cava, which is normally indicative of an unresectable locally advanced tumor. After systemic chemotherapy with gemcitabine and cisplatin, the observed decrease in the level of tumor marker suggested that the cancer was responding to treatment, while radiological findings showed the main tumor shrunk without the presence of distant metastases...
November 2014: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/25614490/partial-nephrectomy-for-hilar-tumors-comparison-of-conventional-open-and-robot-assisted-approaches
#9
COMPARATIVE STUDY
Hideaki Miyake, Nobuyuki Hinata, Satoshi Imai, Junya Furukawa, Kazushi Tanaka, Masato Fujisawa
BACKGROUND: To characterize clinical advantages in robot-assisted partial nephrectomy (RAPN) for targeting renal hilar tumors, and compare them with those of open PN (OPN). METHODS: This study included 31 consecutive patients with renal hilar tumors, consisting of 15 and 16 who received OPN and RAPN, respectively, between January 2012 and May 2014. The perioperative and oncological outcomes of the two approaches were compared. In this series, a hilar tumor was defined as a renal cortical tumor located in the renal hilum that was shown, by preoperative imaging, to be in direct physical contact with the renal artery and/or vein...
August 2015: International Journal of Clinical Oncology
https://www.readbyqxmd.com/read/25410442/efficacy-of-2-port-laparoscopic-surgery-for-gynecologic-disease-invention-of-new-suture-technique
#10
Satoshi Suzuki, Shigenori Furukawa, Miki Ohara, Kiyoshi Kanno, Shun Yasuda, Takeharu Ohzeki, Takafumi Watanabe, Hidenori Takahashi, Hiroshi Suzuki, Keiya Fujimori
BACKGROUND AND OBJECTIVE: To evaluate the efficacy and safety of 2-port laparoscopic surgery for ovarian tumors and uterine leiomyomas. A conventional slip knot under laparoscopic surgery is useful, but it is difficult for beginners. Therefore, we developed new suture technique. METHODS: Between January 2011 and December 2012, 38 patients underwent 2-port total laparoscopic cystectomy (TLC); between January 2010 and December 2011, 45 patients underwent multiport (3 or 4 ports) TLC...
2014: Fukushima Journal of Medical Science
https://www.readbyqxmd.com/read/25390978/cytomegalovirus-retinitis-after-intravitreous-triamcinolone-treatment-of-a-vitrectomized-eye-in-an-immunocompetent-patient
#11
Mariko Furukawa, Kazuyuki Kumagai, Nobuchika Ogino, Satoshi Okinami, Akinori Uemura, Eric Larson
PURPOSE: To report a case of cytomegalovirus (CMV) retinitis after intravitreous injection of triamcinolone for a vitrectomized eye in an immunocompetent patient. DESIGN: Observational case report. METHODS: Review of medical records. RESULTS: A 54-year-old woman with well-controlled type 2 diabetes developed anterior uveitis, papillitis, retinal vasculitis, and retinal exudates 3 months after intravitreous triamcinolone for the treatment of recurred macular edema...
2007: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/25074253/incidence-and-outcome-of-surgical-procedures-after-coronary-artery-bypass-grafting-compared-with-those-after-percutaneous-coronary-intervention-a-report-from-the-coronary-revascularization-demonstrating-outcome-study-in-kyoto-pci-cabg-registry-cohort-2
#12
MULTICENTER STUDY
Akihiro Tokushige, Hiroki Shiomi, Takeshi Morimoto, Koh Ono, Yutaka Furukawa, Yoshihisa Nakagawa, Kazushige Kadota, Kenji Ando, Satoshi Shizuta, Tomohisa Tada, Junichi Tazaki, Yoshihiro Kato, Mamoru Hayano, Mitsuru Abe, Shuichi Hamasaki, Mitsuru Ohishi, Hitoshi Nakashima, Kazuaki Mitsudo, Masakiyo Nobuyoshi, Toru Kita, Yutaka Imoto, Ryuzo Sakata, Hitoshi Okabayashi, Michiya Hanyu, Mitsuomi Shimamoto, Noboru Nishiwaki, Tatsuhiko Komiya, Takeshi Kimura
BACKGROUND: Noncardiac surgery after percutaneous coronary intervention (PCI) has been reported to be carrying high risk for both ischemic and bleeding complications. However, there has been no report comparing the incidence and outcomes of surgical procedures after coronary artery bypass grafting (CABG) with those after PCI. METHODS AND RESULTS: Among 14 383 patients undergoing first coronary revascularization (PCI, n=12 207; CABG, n=2176) enrolled in the Coronary Revascularization Demonstrating Outcome Study in Kyoto (CREDO-Kyoto) PCI/CABG Registry Cohort-2, surgical procedures were performed more frequently after CABG (n=560) than after PCI (n=2398; cumulative 3-year incidence: 27% versus 22%; unadjusted P<0...
August 2014: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/24657445/3-5-6-7-8-3-4-heptamethoxyflavone-a-citrus-flavonoid-on-protection-against-memory-impairment-and-neuronal-cell-death-in-a-global-cerebral-ischemia-mouse-model
#13
Satoshi Okuyama, Mayu Morita, Kazuhiro Miyoshi, Yuki Nishigawa, Miki Kaji, Atsushi Sawamoto, Tsukasa Terugo, Nobuki Toyoda, Nahomi Makihata, Yoshiaki Amakura, Morio Yoshimura, Mitsunari Nakajima, Yoshiko Furukawa
The present study evaluated the effects of treatment with the citrus flavonoid, 3,5,6,7,8,3',4'-heptamethoxyflavone (HMF) on protection against memory impairment and neuronal death in a global cerebral ischemia mouse model. The results showed that HMF, administrated for three days immediately after ischemic surgery, protected against ischemia-induced memory dysfunction, rescued neuronal cell death in the CA1 cell layer, increased the production of BDNF, stimulated the autophosphorylation of CaMK II and suppressed microglial activation in the hippocampus...
May 2014: Neurochemistry International
https://www.readbyqxmd.com/read/24256464/improvement-of-long-term-outcomes-in-pancreatic-cancer-and-its-associated-factors-within-the-gemcitabine-era-a-collaborative-retrospective-multicenter-clinical-review-of-1-082-patients
#14
MULTICENTER STUDY
Taira Kuroda, Teru Kumagi, Tomoyuki Yokota, Hirotaka Seike, Mari Nishiyama, Yusuke Imai, Nobu Inada, Naozumi Shibata, Satoshi Imamine, Shin-ichi Okada, Mitsuhito Koizumi, Hirofumi Yamanishi, Nobuaki Azemoto, Jiro Miyaike, Yoshinori Tanaka, Haruka Tatsukawa, Hiroki Utsunomiya, Yoshinori Ohno, Teruki Miyake, Masashi Hirooka, Shinya Furukawa, Masanori Abe, Yoshiou Ikeda, Bunzo Matsuura, Yoichi Hiasa, Morikazu Onji
BACKGROUND: Although the outcomes of pancreatic cancer have been improved by gemcitabine, the changes in its characteristics and long-term outcomes within the gemcitabine era remain unclear. This study was conducted to identify clinical characteristics of pancreatic cancer patients within the gemcitabine era. METHODS: A retrospective chart review was performed at 10 centers for 1,248 consecutive patients who were ever considered to have a diagnosis of pancreatic cancer between 2001 and 2010...
2013: BMC Gastroenterology
https://www.readbyqxmd.com/read/23823622/enhanced-intestinal-motility-during-oral-glucose-tolerance-test-after-laparoscopic-sleeve-gastrectomy-preliminary-results-using-cine-magnetic-resonance-imaging
#15
Vo Nguyen Trung, Hiroshi Yamamoto, Akira Furukawa, Tsuyoshi Yamaguchi, Satoshi Murata, Masahiro Yoshimura, Yoko Murakami, Shigetaka Sato, Hideji Otani, Satoshi Ugi, Katsutaro Morino, Hiroshi Maegawa, Tohru Tani
BACKGROUND: Enhanced secretion of glucagon-like peptide-1 (GLP-1) has been suggested as a possible mechanism underlying the improvement in type 2 diabetes mellitus (T2DM) after laparoscopic sleeve gastrectomy (LSG). However, the reason for enhanced GLP-1 secretion during glucose challenge after LSG remains unclear because LSG does not include intestinal bypass. In this study, we focused on the effects of LSG on GLP-1 secretion and intestinal motility during the oral glucose tolerance test (OGTT) using cine magnetic resonance imaging (MRI) before and 3 months after LSG...
2013: PloS One
https://www.readbyqxmd.com/read/23015155/influence-of-initial-acute-myocardial-infarction-presentation-on-the-outcome-of-surgical-procedures-after-coronary-stent-implantation-a-report-from-the-credo-kyoto-pci-cabg-registry-cohort-2
#16
MULTICENTER STUDY
Akihiro Tokushige, Hiroki Shiomi, Takeshi Morimoto, Koh Ono, Yutaka Furukawa, Yoshihisa Nakagawa, Kazushige Kadota, Masashi Iwabuchi, Satoshi Shizuta, Tomohisa Tada, Junichi Tazaki, Yoshihiro Kato, Mamoru Hayano, Mitsuru Abe, Shuichi Hamasaki, Chuwa Tei, Hitoshi Nakashima, Kazuaki Mitsudo, Masakiyo Nobuyoshi, Toru Kita, Takeshi Kimura
Several previous publications have consistently reported that surgical procedures performed early after coronary stenting were associated with significantly higher risk for ischemic events than those performed late. In the current post hoc analysis of the Coronary REvascularization Demonstrating Outcome Study in Kyoto PCI/coronary artery bypass grafting Registry Cohort-2, we compared the outcomes of early (within 42 days) versus late surgery (beyond 42 days) after coronary stenting stratified by the initial clinical presentations [acute myocardial infarction (AMI) [early N = 153, and late N = 586] and non-AMI (early N = 202, and late N = 1457)]...
January 2013: Cardiovascular Intervention and Therapeutics
https://www.readbyqxmd.com/read/22889349/two-cases-of-paraovarian-tumor-of-borderline-malignancy
#17
Satoshi Suzuki, Shigenori Furukawa, Hyo Kyozuka, Takafumi Watanabe, Hidenori Takahashi, Keiya Fujimori
Paraovarian tumor of borderline malignancy is rare. Only 13 cases in Japan, including the present cases, and 40 cases overseas have been reported. We report two cases of paraovarian tumor of borderline malignancy. Case 1: A 38-year-old woman was found to have a right ovarian cyst. Transvaginal ultrasonography showed a unilocular cystic tumor and a solid part of 8 mm in diameter within the tumor. Malignancy could not be ruled out, therefore the laparotomy was performed. The tumor was paraovarian tumor. Intraoperative rapid histological diagnosis was made and the patient was diagnosed with a serous borderline tumor...
January 2013: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/22888162/impact-of-aortic-regurgitation-on-the-prognosisof-severe-aortic-stenosis
#18
COMPARATIVE STUDY
Satoshi Honda, Takeshi Kitai, Yukikatsu Okada, Tomoko Tani, Kitae Kim, Shuichiro Kaji, Natsuhiko Ehara, Makoto Kinoshita, Atsushi Kobori, Atsushi Yamamuro, Toru Kita, Yutaka Furukawa
OBJECTIVE: Many patients with aortic stenosis (AS) have coexisting aortic regurgitation (AR). However, few data exist regarding its clinical significance and prognostic value. The aim of this study was to examine the effect of concomitant significant AR on clinical outcomes in patients with non-surgically treated severe AS. DESIGN: A single centre, retrospective cohort study. PATIENTS AND METHODS: We retrospectively reviewed 306 consecutive patients (age, 72±11 years) with severe AS in whom non-surgical management was primarily planned at our institution between January 1999 and December 2011...
November 2012: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/22610162/takotsubo-cardiomyopathy-associated-with-pulmonary-resections-after-induction-chemoradiotherapy-for-non-small-cell-lung-cancer
#19
Shinichi Toyooka, Satoshi Akagi, Masashi Furukawa, Kazufumi Nakamura, Junichi Soh, Masaomi Yamane, Takahiro Oto, Shinichiro Miyoshi
Takotsubo cardiomyopathy (TTC), also known as transient left ventricular (LV) apical ballooning syndrome, is characterized by transient LV dysfunction. We present the case of a 72-year-old man who was diagnosed as having TTC after surgery for two lung tumors. The patient was treated with induction chemoradiotherapy (CRT) followed by pulmonary resections for double primary non-small cell lung cancers (NSCLC): cT4N1M0 disease in the right lung and cT2N0M0 in the left lung. Induction CRT was performed. A right upper lobectomy was initially performed, and a left upper divisionectomy was subsequently performed...
September 2012: General Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/22580652/intrahepatic-cholangiojejunostomy-longmire-procedure-for-recurrent-bilioenteric-anastomotic-stricture-with-hepatolithiasis
#20
Hiroaki Shimizu, Fumio Kimura, Hiroyuki Yoshidome, Masayuki Ohtsuka, Atsushi Kato, Hideaki Yoshitomi, Satoshi Nozawa, Katunori Furukawa, Noboru Mitsuhashi, Dan Takeuchi, Tukasa Takayashiki, Kosuke Suda, Masaru Miyazaki
Interventional procedure via percutaneous transhepatic route is often performed, as an initial treatment, in patients with benign bilioenteric anastomotic stricture. However, surgical management is required in most cases in which radiological intervention is unsuccessful. In this report, we describe a case of a 67-year-old woman with recurrent bilioenteric anastomotic stricture, accompanying bilateral hepatolitiasis after several times of transhepatic interventions. The patient underwent intrahepatic cholangiojejunostomy (Longmire procedure) and cholangioscopic lithotomy after resection of an atrophic left lateral segment resulting from hepatolithiasis...
June 2012: Hepato-gastroenterology
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