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Daniel S Thoma, Nadja Naenni, Goran I Benic, Christoph H F Hämmerle, Ronald E Jung
AIM: To test whether or not soft tissue augmentation with a collagen matrix (VCMX) leads to a similar increase in ridge width around dental implants compared to the use of an autogenous subepithelial connective tissue graft (SCTG). MATERIALS AND METHODS: In 12 dogs, immediate dental implants were placed with simultaneous guided bone regeneration. Three months later, soft tissue volume augmentation was performed by randomly allocating three treatment modalities to these sites (VCMX, SCTG, sham-operated group (control))...
October 7, 2016: Journal of Clinical Periodontology
Daeyoung Kim, Eun Yeon Joo, Dae-Won Seo, Min-Young Kim, Yong-Ho Lee, Hyuk Chan Kwon, Jae-Moon Kim, Seung Bong Hong
BACKGROUND: We conducted the study to examine accuracy of the magnetoencephalography (MEG) spike source localization in presurgical evaluation of patients with medically refractory focal epilepsy. METHODS: Ten consecutive patients with refractory focal epilepsy who were candidates for two-stage surgery with long-term intracranial electroencephalography (ICEEG) monitoring were enrolled. Interictal MEG recordings with simultaneous scalp EEG were obtained within 7days before the ICEEG electrode implantation...
August 16, 2016: Epilepsy Research
Jamal Hassan Assaf, Débora do Canto Assaf, Raquel Pippi Antoniazzi, Leandro Berni Osório, Fabiana Mantovani Gomes França
BACKGROUND: The aim of the study was to evaluate a new technique for treating dehiscence buccal bone sites (Class 2) with immediate implant and collagen-enriched bovine-derived xenograft blocks without a surgical flap or membrane. MATERIALS AND METHODS: Individuals with at least 5 mm of buccal bone dehiscence were selected for a flapless surgical approach to insert xenografts blocks into buccal dehiscence defects as well as the gap between the implant and the residual bone wall...
September 13, 2016: Journal of Periodontology
Lauranne Sins, Patrice Tétreault, Natalia Nuño, Nicola Hagemeister
Prosthetic components mismatch and subscapularis tear are determining factors for glenoid failure complication in non-conforming total shoulder arthroplasty. Risk factors are linked to glenoid prosthetic loading. However, the mechanisms underlying the clinical observations remain unclear. This study assessed the combined impact of mismatch and subscapularis tear on glenoid loading. It was assumed that adequate glenoid loading was associated with minimal, but non-null, humeral head translations and contact pressure, as well as with maximal glenoid contact area, and that the center of pressure on the glenoid would have a centered displacement pattern...
September 12, 2016: Journal of Biomechanical Engineering
Hiraku Iramina, Mitsuhiro Nakamura, Yusuke Iizuka, Takamasa Mitsuyoshi, Yukinori Matsuo, Takashi Mizowaki, Masahiro Hiraoka, Ikuo Kanno
PURPOSE: To quantify the accuracy of extracted target motion trajectories in dual-source four-dimensional cone-beam computed tomography (4D-CBCT) by comparison with the actual three-dimensional (3D) target motion acquired simultaneously during 4D-CBCT scan. MATERIALS AND METHODS: 4D-CBCT scans were performed for 19 different sinusoidal-like patterns and 13 lung cancer patients with implanted markers. Internal (In) or external (Ex) surrogates with amplitude (Amp)- or phase (Ph)-based sorting were used for the reconstructions...
August 12, 2016: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
Shih-Jie Lin, Kuo-Chin Huang, Po-Yao Chuang, Chien-Yin Lee, Tsan-Wen Huang, Mel S Lee, Robert Wen-Wei Hsu
BACKGROUND: The Russel-Taylor type 2B fractures compromised the trochanteric region and medial buttress of proximal femur. This fracture pattern limits the choice of implants and raises the risk of adverse outcomes. We aimed to (i) determine the outcome of Russel-Taylor type 2B fractures treated using reverse less invasive stabilization system plates (LISS-DF) and to (ii) learn what factors affected outcomes after osteosynthesis with reverse LISS plates. DESIGN: A retrospective study SETTING: The study was conducted at a Level III trauma center in Taiwan...
October 2016: Injury
G Bonfort, D T Nguyen, C Rumeau, R Jankowski
OBJECTIVES: The facial implantation of the osseous nasal pyramid corresponds to the piriform aperture, the shape of which is projected on the facial skin in the form of bracket-shaped parentheses. The objective of this study was to compare inter-parenthesis width with subjective visibility on frontal photographs. MATERIAL AND METHODS: The "patient" group came from a retrospective cohort of photographs taken ahead of septorhinoplasty. The "model" group photographs were collected from the Web or magazines...
July 14, 2016: European Annals of Otorhinolaryngology, Head and Neck Diseases
Gianluca Caiazzo, Giovanni Longo, Alessandra Giavarini, Ismail Dogu Kilic, Enrico Fabris, Roberta Serdoz, Alessio Mattesini, Nicolas Foin, Gioel Gabrio Secco, Salvatore De Rosa, Ciro Indolfi, Carlo Di Mario
BACKGROUND: The effect of optical coherence tomography (OCT) guidance on the implantation strategy during all phases of percutaneous coronary intervention (PCI) with bioresorbable vascular scaffolds (BVSs) in a real-world scenario has been poorly investigated. METHODS: Consecutive patients undergoing BVS implantation at our institution were included in this registry. Frequency-domain OCT pullbacks were performed at the operator's discretion during all phases of BVS implantation procedures to optimize preparation of lesions, confirm BVS size, and optimize expansion and apposition of scaffolds...
October 15, 2016: International Journal of Cardiology
Matteo Pagnesi, Enrico A Martino, Mauro Chiarito, Antonio Mangieri, Richard J Jabbour, Nicolas M Van Mieghem, Susheel K Kodali, Cosmo Godino, Giovanni Landoni, Antonio Colombo, Azeem Latib
BACKGROUND: The aims of this study were: 1) to evaluate silent cerebral injury detected by cerebral diffusion weighted magnetic resonance imaging (DW-MRI) after transcatheter aortic valve implantation (TAVI); and 2) to assess the efficacy of embolic protection devices (EPDs) on DW-MRI endpoints. METHODS: We included in a pooled analysis 25 prospective studies reporting post-procedural cerebral DW-MRI data after TAVI (n=1225). Among these studies, we included in a meta-analysis 6 studies investigating TAVI performed with versus without EPDs (n=384)...
October 15, 2016: International Journal of Cardiology
Xinping Hao, Shubin Chen, Zilong Yu, Fenghe Liang, Yongxin Li
OBJECTIVE: To investigate the feasibility of the treatment of otosclerosis using laser stapedotomy with mini incision in the external auditory meatus. METHOD: Thirteen patients(15 ears) with otosclerosis evidence on clinic history. They were all operated using the laser assisted stapedotomy by mini incision in external auditory meatus because of the wide straight canal. Laser resection the tendo musculistapedius and anterior and postrior arch, breaking the articulatioincudostapedia, removing the stapes superstructure, making a hole of 6mm diameter in the rear of stapes footplate by laser drilling, implanting the corresponding length Piston artificial ossicle...
March 2016: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
Tim Kinnaird, Mehmood Butt, Fairoz Abdul, Khaled Yazji, Ahmed Hailan, Sean Gallagher, Nicholas Ossei-Gerning, Alexander Chase, Anirban Choudhury, David Smith, Richard Anderson
INTRODUCTION: Prolonged dual anti-platelet therapy (DAPT) may cause excess bleeding in certain patients. The biolimus-A9 drug-coated stent (BA9-DCS) has a rapid drug-elution profile allowing shortened DAPT. Data were gathered on the early experience implanting this stent in drug-eluting stent eligible patients deemed to be at high risk of bleeding. BACKGROUND AND METHODS: The demographics, procedural data and clinical outcomes were gathered prospectively for 249 patients treated with a BA9-DCS stent at 2 UK centres, and compared to a cohort of patients treated in the same period with drug-eluting stents (PCI-DES)...
2016: PloS One
Huibo Li, Jigang Lou, Hao Liu, Beiyu Wang
OBJECTIVES: Cervical total disc replacement (TDR) is an emerging technology. Cervical arthroplasty theoretically reduces the risk of adjacent level disc degeneration and segmental instability. However, the factors that influence postoperative range of motion (ROM) and clinical outcomes are not fully understood. The aim of our study was to evaluate the effect of intervertebral disc height on the range of motion and clinical outcomes after single-level implantation of Prestige LP cervical disc prosthesis METHODS: A total of 160 patients with single-level Prestige LP cervical disc prosthesis were evaluated...
September 2016: Clinical Neurology and Neurosurgery
Jonathan G Eastman, James C Krieg, Milton L Chip Routt
INTRODUCTION: Operative fixation of a disrupted symphysis pubis helps return alignment and stability to a traumatized pelvic ring. Implant loosening or failure has been demonstrated to commonly occur at some subacute point during the postoperative period. The purpose of this study is to report on a series of patients with traumatic pelvic ring disruptions to determine the incidence and common factors associated with early postoperative symphyseal plate failure before 7 weeks. MATERIALS AND METHODS: 126 patients retrospectively identified with unstable pelvic injuries treated with open reduction and plate fixation of the symphysis pubis and iliosacral screw fixation...
August 2016: Injury
Prerak Gupta, Manishekhar Kumar, Nandana Bhardwaj, Jadi Praveen Kumar, C S Krishnamurthy, Samit Kumar Nandi, Biman B Mandal
Autologous graft replacement as a strategy to treat diseased peripheral small diameter (≤6 mm) blood vessel is often challenged by prior vein harvesting. To address this issue, we fabricated native-tissue mimicking multilayered small diameter vascular graft (SDVG) using mulberry (Bombyx mori) and Indian endemic non-mulberry (Antheraea assama and Philosamia ricini) silk. Patterned silk films were fabricated on microgrooved PDMS mold, casted by soft lithography. The biodegradable patterned film templates with aligned cell sheets were rolled onto an inert mandrel to mimic vascular conduit...
June 29, 2016: ACS Applied Materials & Interfaces
Tonghui Xu, Qiuhong Yang, Ruoxi Liu, Wenfu Wang, Shuanglian Wang, Chuanyong Liu, Jingxin Li
Most studies have demonstrated that alcohol consumption is associated with decreased fertility. The aim of this study was to investigate the effects of alcohol on pre-implantation embryo transport and/or early embryo development in the oviduct. We reported here that ethanol concentration-dependently suppressed the spontaneous motility of isolated human oviduct strips (EC50 50±6mM), which was largely attenuated in the present of L-NAME, a classical nitric oxide synthase(NOS) competitive inhibitor. Notably, either acute or chronic alcohol intake delayed egg transport and retarded early development of the embryo in the mouse oviduct, which was largely rescued by co-administration of L-NAME in a acute alcohol intake group but not in chronic alcohol intake group...
May 16, 2016: Toxicology
Tzu-Hua Lin, Jukka Pajarinen, Taishi Sato, Florence Loi, Changchun Fan, Luis A Córdova, Akira Nabeshima, Emmanuel Gibon, Ruth Zhang, Zhenyu Yao, Stuart B Goodman
UNLABELLED: Total joint replacement is a cost-effective surgical procedure for patients with end-stage arthritis. Wear particle-induced chronic inflammation is associated with the development of periprosthetic osteolysis. Modulation of NF-κB signaling in macrophages, osteoclasts, and mesenchymal stem cells could potentially mitigate this disease. In the current study, we examined the effects of local delivery of decoy NF-κB oligo-deoxynucleotide (ODN) on wear particle-induced bone loss in a murine continuous femoral particle infusion model...
September 1, 2016: Acta Biomaterialia
Verena Tscholl, Abdullah Khaled-A Lsharaf, Tina Lin, Barbara Bellmann, Sebastian Biewener, Patrick Nagel, Saba Suhail, Klaus Lenz, Ulf Landmesser, Mattias Roser, Andreas Rillig
BACKGROUND: The efficacy of the second-generation cryoballoon (CB) in patients with paroxysmal atrial fibrillation (AF) has been demonstrated previously. Data on the efficacy of CB ablation in patients with persistent AF are sparse. OBJECTIVE: The aim of this study was to evaluate the 2-year success rate of pulmonary vein isolation in patients with persistent AF using the second-generation CB. METHODS: Fifty consecutive patients (mean age 64...
September 2016: Heart Rhythm: the Official Journal of the Heart Rhythm Society
Andre Walter, Brigitte Wendl, Oliver Ploder, Sergi Mojal, Andreu Puigdollers
BACKGROUND: The aim was to test which component [wire arm, connecting abutment attachment, and orthodontic mini-implant (OMI)] of the force-transmitting system (FTS) in the anterior palate of three commonly used hybrid expanders (HEs; WILMES-HE, LUDWIG-HE, and WINSAUER-HE) deforms under increasing load. MATERIALS AND METHODS: Crude single and double wire arms were tested individually. Non-opening of the maxillae halves was simulated in artificial bone blocks with single wire and double wire FTS specimens...
April 1, 2016: European Journal of Orthodontics
Rafael Narciso Franklin, Pierre Galvagni Silveira, Jorge Rufino Ribas Timi, Jason T Lee, Gilberto do Nascimento Galego, Cristiano Torres Bortoluzzi
BACKGROUND: The Octopus technique is an off-label and off-the-shelf strategy used as an option in the management of some specific and selected cases of thoracoabdominal aortic aneurysms (TAAA). We sought to compare 2 different methods of measurements on computed tomography (CT) slices and to evaluate the accommodation and conformability, before and after ballooning, of the components used in the Octopus technique. METHODS: The CT gutter analysis between the 3 stent grafts within the short docking limb of the Excluder(®) was made using Viabahns(®) of 8, 7, and 6 mm in diameter...
May 2016: Annals of Vascular Surgery
Juri A Steiner, Stephen J Ferguson, G Harry van Lenthe
Secure fracture fixation is still a major challenge in orthopedic surgery, especially in osteoporotic bone. While numerous studies have investigated the effect of implant loading on the peri-implant bone after screw insertion, less focus has been put on bone damage that may occur due to the screw insertion process itself. Therefore, the aim of this study was to localize and quantify peri-implant bone damage caused by screw insertion. We used non-invasive three-dimensional micro-computed tomography to scan twenty human femoral bone cores before and after screw insertion...
April 2016: Medical Engineering & Physics
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