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S Furukawa

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https://www.readbyqxmd.com/read/28069106/portal-vein-thrombosis-after-reconstruction-in-270-consecutive-patients-with-portal-vein-resections-in-hepatopancreatobiliary-hpb-surgery
#1
Masaru Miyazaki, Hiroaki Shimizu, Masayuki Ohtuka, Atsushi Kato, Hiroyuki Yoshitomi, Katsunori Furukawa, Tsukasa Takayashiki, Satoshi Kuboki, Shigetsugu Takano, Daisuke Suzuki, Taku Higashihara
BACKGROUNDS: This study was aimed to evaluate the occurrence of portal vein thrombosis after portal vein reconstruction. METHODS: The portal veins were repaired with venorrhaphy, end-to-end, patch graft, and segmental graft in consecutive 270 patients undergoing hepato-pancreto-biliary (HPB) surgery. RESULTS: Portal vein thrombosis was encountered in 20 of 163 of end-to-end, 2 of 56 of venorrhaphy, and 2 of 5 of patch graft groups, as compared with 0 of 46 of segmental graft group (p < 0...
December 24, 2016: American Journal of Surgery
https://www.readbyqxmd.com/read/27995327/quantitative-diagnosis-of-chronic-pancreatitis-using-eus-elastography
#2
Takamichi Kuwahara, Yoshiki Hirooka, Hiroki Kawashima, Eizaburo Ohno, Takuya Ishikawa, Manabu Kawai, Hiroki Suhara, Tomoaki Takeyama, Kiyotaka Hashizume, Toshinari Koya, Hiroyuki Tanaka, Daisuke Sakai, Takeshi Yamamura, Kazuhiro Furukawa, Kohei Funasaka, Masanao Nakamura, Ryoji Miyahara, Osamu Watanabe, Masatoshi Ishigami, Senju Hashimoto, Hidemi Goto
BACKGROUND: It is difficult to diagnose chronic pancreatitis (CP) objectively because of a lack of standard diagnostic criteria. Endoscopic ultrasonography (EUS) has been used to assess the severity of CP, but the diagnosis of CP using EUS depends on an endosnonographer. The aim of this study was to establish an objective diagnostic method for CP using EUS elastography (EUS-EG). METHODS: A retrospective study was designed and 96 patients underwent EUS-EG for follow-up of known CP, or who were clinically suspected as having CP...
December 19, 2016: Journal of Gastroenterology
https://www.readbyqxmd.com/read/27994106/resistance-to-first-line-antituberculosis-drugs-in-washington-state-by-region-of-birth-and-implications-for-latent-tuberculosis-treatment-among-foreign-born-individuals
#3
Nathan W Furukawa, Mahri Z Haider, Sheanne J Allen, Sherry L Carlson, Scott W Lindquist
The United States has a low burden of drug resistance among tuberculosis (TB) cases compared with other world regions. TB is increasingly concentrated among foreign-born individuals who have higher rates of drug resistance than U.S.-born individuals. While universal drug susceptibility testing is the standard for detecting active tuberculosis, there are limited guidelines for latent tuberculosis infection (LTBI) treatment based on risk factors for drug resistance. To quantify the variable risk of drug resistance among foreign-born individuals, all TB cases in Washington State between 1994 and 2014 with drug resistance data for isoniazid, rifampin, pyrazinamide, and ethambutol were divided into eight regions of birth...
December 19, 2016: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/27993950/in-situ-straining-and-time-resolved-electron-tomography-data-acquisition-in-a-transmission-electron-microscope
#4
S Hata, S Miyazaki, T Gondo, K Kawamoto, N Horii, K Sato, H Furukawa, H Kudo, H Miyazaki, M Murayama
This paper reports the preliminary results of a new in-situ three-dimensional (3D) imaging system for observing plastic deformation behavior in a transmission electron microscope (TEM) as a directly relevant development of the recently reported straining-and-tomography holder [Sato K et al (2015) Development of a novel straining holder for transmission electron microscopy compatible with single tilt-axis electron tomography. Microsc. 64: 369-375]. We designed an integrated system using the holder and newly developed straining and image-acquisition software and then developed an experimental procedure for in-situ straining and time-resolved electron tomography (ET) data acquisition...
December 18, 2016: Microscopy
https://www.readbyqxmd.com/read/27983908/calcium-concentration-in-culture-medium-as-a-nondestructive-and-rapid-marker-of-osteogenesis
#5
Yohei Tanikake, Manabu Akahane, Akira Furukawa, Yasuaki Tohma, Yusuke Inagaki, Tsutomu Kira, Yasuhito Tanaka
Artificial bones made of &#946;-tricalcium phosphate (&#946;-TCP) combined with bone marrowderived stromal cells (BMSCs) are used for effective reconstruction of bone defects caused by genetic defects, traumatic injury, or surgical resection of bone tumors. However, the selection of constructs with high osteogenic potential before implantation is challenging. The purpose of this study was to determine whether the calcium concentration in BMSC culture medium can be used as a nondestructive and simple osteogenic marker for selecting tissueengineered grafts constructed using &#946;-TCP and BMSCs...
November 29, 2016: Cell Transplantation
https://www.readbyqxmd.com/read/27865193/different-clinical-outcomes-in-patients-with-asymptomatic-severe-aortic-stenosis-according-to-the-stage-classification-does-the-aortic-valve-area-matter
#6
Takeshi Kitai, Tomohiko Taniguchi, Takeshi Morimoto, Toshiaki Toyota, Chisato Izumi, Shuichiro Kaji, Kitae Kim, Naritatsu Saito, Kazuya Nagao, Tsukasa Inada, Eri Minamino-Muta, Takao Kato, Moriaki Inoko, Katsuhisa Ishii, Tadaaki Koyama, Ryuzo Sakata, Yutaka Furukawa, Takeshi Kimura
BACKGROUND: The ACC/AHA guidelines introduced a new classification of severe aortic stenosis (AS) mainly based on maximum jet velocity (Vmax) and mean pressure gradient (mPG), but not on aortic valve area (AVA). However, prognostic value of this new classification has not yet been fully evaluated. METHODS AND RESULTS: We studied 1512 patients with asymptomatic severe AS enrolled in the CURRENT AS registry in whom surgery was not initially planned. Patients were divided into 2 groups: Group 1 (N=122) comprised patients who met the recommendation for surgery; high-gradient (HG)-AS (Vmax≥4...
February 1, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/27853168/depressive-symptoms-and-prevalence-of-erectile-dysfunction-in-japanese-patients-with-type-2-diabetes-mellitus-the-dogo-study
#7
S Furukawa, T Sakai, T Niiya, H Miyaoka, T Miyake, S Yamamoto, K Maruyama, T Ueda, H Senba, M Torisu, H Minami, M Onji, T Tanigawa, B Matsuura, Y Hiasa, Y Miyake
In several studies of patients with type 2 diabetes mellitus, a positive association between depressive symptoms and erectile dysfunction (ED) has been reported. No evidence exists, however, regarding the association between depressive symptoms and ED among Japanese patients with type 2 diabetes mellitus. Thus, we examined this issue among Japanese patients with type 2 diabetes mellitus. Study subjects were 469 male Japanese patients with type 2 diabetes mellitus, aged 19 years or over. ED, moderate to severe ED and severe ED were defined as present when a subject had a Sexual Health Inventory for Men score <22, <12 and <8, respectively...
November 17, 2016: International Journal of Impotence Research
https://www.readbyqxmd.com/read/27829665/the-role-of-common-protective-alleles-hla-drb1-13-among-systemic-autoimmune-diseases
#8
REVIEW
H Furukawa, S Oka, N Tsuchiya, K Shimada, A Hashimoto, S Tohma, A Kawasaki
Associations between human leukocyte antigen (HLA) and susceptibility to systemic autoimmune diseases have been reported. The predisposing alleles are variable among ethnic groups and/or diseases. On the other hand, some HLA alleles are associated with resistance to systemic autoimmune diseases, including systemic sclerosis, systemic lupus erythematosus and rheumatoid arthritis. Interestingly, DRB1*13 alleles are the protective alleles shared by multiple autoimmune diseases. DRB1*13:01 allele is protective in European populations and DRB1*13:02 in Japanese...
November 10, 2016: Genes and Immunity
https://www.readbyqxmd.com/read/27802546/safety-and-wound-outcomes-following-genetically-corrected-autologous-epidermal-grafts-in-patients-with-recessive-dystrophic-epidermolysis-bullosa
#9
Zurab Siprashvili, Ngon T Nguyen, Emily S Gorell, Kylie Loutit, Phuong Khuu, Louise K Furukawa, H Peter Lorenz, Thomas H Leung, Douglas R Keene, Kerri E Rieger, Paul Khavari, Alfred T Lane, Jean Y Tang, M Peter Marinkovich
Importance: Recessive dystrophic epidermolysis bullosa (RDEB) is a devastating, often fatal, inherited blistering disorder caused by mutations in the COL7A1 gene encoding type VII collagen. Support and palliation are the only current therapies. Objective: To evaluate the safety and wound outcomes following genetically corrected autologous epidermal grafts in patients with RDEB. Design, Setting, and Participants: Single-center phase 1 clinical trial conducted in the United States of 4 patients with severe RDEB with a measured area of wounds suitable for grafting of at least 100 cm2...
November 1, 2016: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/27797445/tau-imaging-with-18-f-thk-5351-in-progressive-supranuclear-palsy
#10
A Ishiki, R Harada, N Okamura, N Tomita, C C Rowe, V L Villemagne, K Yanai, Y Kudo, H Arai, S Furumoto, M Tashiro, K Furukawa
BACKGROUND AND PURPOSE: Visualization of pathogenic protein aggregates is crucial to elucidate pathomechanisms and to make an accurate diagnosis in many neurodegenerative conditions. Aggregates of the microtubule-binding protein, tau, are one of the most important pathogenic molecules in neurodegenerative disorders. Progressive supranuclear palsy (PSP) is characterized by the deposition of tau proteins in some specific area such as the basal ganglia and brainstem. We tried to detect tau lesions in the brains of living patients with PSP with a novel positron emission tomography (PET) tracer, [(18) F]THK-5351, which we have recently developed...
January 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/27784886/diabetic-peripheral-neuropathy-and-prevalence-of-erectile-dysfunction-in-japanese-patients-aged-65-years-with-type-2-diabetes-mellitus-the-dogo-study
#11
S Furukawa, T Sakai, T Niiya, H Miyaoka, T Miyake, S Yamamoto, K Maruyama, T Ueda, H Senba, Y Todo, M Torisu, H Minami, M Onji, T Tanigawa, B Matsuura, Y Hiasa, Y Miyake
Only limited epidemiological evidence exists regarding the relationship between diabetic neuropathy and erectile dysfunction (ED) among Japanese patients with type 2 diabetes mellitus. To investigate the relationship between diabetic neuropathy and ED among Japanese patients with type 2 diabetes mellitus, a multicenter cross-sectional study was conducted in 287 male Japanese patients with type 2 diabetes mellitus, age (19-65 years). Diabetic neuropathy was diagnosed if the patients showed two or more of the following three characteristics: neuropathic symptoms, decreased or disappeared Achilles tendon reflex and/or abnormal vibration perception...
October 27, 2016: International Journal of Impotence Research
https://www.readbyqxmd.com/read/27773607/identification-of-4-mercapto-4-methylpentan-2-one-as-the-characteristic-aroma-of-sake-made-from-low-glutelin-rice
#12
Sachiko Iizuka-Furukawa, Atsuko Isogai, Kazutaka Kusaka, Tsutomu Fujii, Yoshinori Wakai
The grassy characteristic aroma perceived in brewed sake made from low-glutelin rice (Oryza sativa L. Mizuhonoka) was examined by gas chromatography-olfactometry and gas chromatography-mass spectrometry. By comparing the odor properties and Kovats retention indices to those of standard compounds, 4-mercapto-4-methylpentan-2-one (4MMP) was found to contribute to the characteristic aroma. Sake brewing using Mizuhonoka, low-glutelin rice, and Gin-ohmi (a control) revealed that 4MMP concentrations in Mizuhonoka sake samples were higher than those in Gin-ohmi samples over the fermentation period...
October 20, 2016: Journal of Bioscience and Bioengineering
https://www.readbyqxmd.com/read/27690434/passive-membrane-permeability-in-cyclic-peptomer-scaffolds-is-robust-to-extensive-variation-in-side-chain-functionality-and-backbone-geometry
#13
Akihiro Furukawa, Chad E Townsend, Joshua Schwochert, Cameron R Pye, Maria A Bednarek, R Scott Lokey
Synthetic and natural cyclic peptides provide a testing ground for studying membrane permeability in nontraditional drug scaffolds. Cyclic peptomers, which incorporate peptide and N-alkylglycine (peptoid) residues, combine the stereochemical and geometric complexity of peptides with the functional group diversity accessible to peptoids. We synthesized cyclic peptomer libraries by split-pool techniques, separately permuting side chain and backbone geometry, and analyzed their membrane permeabilities using the parallel artificial membrane permeability assay...
October 27, 2016: Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/27672730/isolation-of-baker-s-yeast-mutants-with-proline-accumulation-that-showed-enhanced-tolerance-to-baking-associated-stresses
#14
Ariunzaya Tsolmonbaatar, Keisuke Hashida, Yukiko Sugimoto, Daisuke Watanabe, Shuhei Furukawa, Hiroshi Takagi
During bread-making processes, yeast cells are exposed to baking-associated stresses such as freeze-thaw, air-drying, and high-sucrose concentrations. Previously, we reported that self-cloning diploid baker's yeast strains that accumulate proline retained higher-level fermentation abilities in both frozen and sweet doughs than the wild-type strain. Although self-cloning yeasts do not have to be treated as genetically modified yeasts, the conventional methods for breeding baker's yeasts are more acceptable to consumers than the use of self-cloning yeasts...
December 5, 2016: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/27611786/evidence-for-increased-behavioral-control-by-punishment-in-children-with-attention-deficit-hyperactivity-disorder
#15
E Furukawa, B Alsop, P Sowerby, S Jensen, G Tripp
BACKGROUND: The behavioral sensitivity of children with ADHD to punishment has received limited theoretical and experimental attention. This study evaluated the effects of punishment on the response allocation of children with ADHD and typically developing children. METHOD: Two hundred and ten children, 145 diagnosed with ADHD, completed an operant task in which they chose between playing two simultaneously available games. Reward was arranged symmetrically across the games under concurrent variable interval schedules...
September 9, 2016: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/27597530/influence-of-aortic-valve-leaflet-calcification-on-dynamic-aortic-valve-motion-assessed-by-cardiac-computed-tomography
#16
Keisuke Minami, Kihei Yoneyama, Masaki Izumo, Kengo Suzuki, Yasuyoshi Ogawa, Kousuke Chikaraishi, Yukihisa Ogawa, Yasuyuki Kobayashi, Toshiyuki Furukawa, Yasuhiro Tanabe, Yoshihiro J Akashi
BACKGROUND: Computed tomography is the best noninvasive imaging modality for evaluating valve leaflet calcification. OBJECTIVE: To evaluate the association of aortic valve leaflet calcification with instantaneous valve opening and closing using dynamic multidetector computed tomography (MDCT). METHODS: We retrospectively evaluated 58 consecutive patients who underwent dynamic MDCT imaging. Aortic valve calcification (AVC) was quantified using the Agatston method...
November 2016: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/27580577/prevalence-and-characteristics-of-salmonella-and-campylobacter-in-retail-poultry-meat-in-japan
#17
Ichiro Furukawa, Tomoe Ishihara, Hiroshi Teranishi, Shioko Saito, Jun Yatsuyanagi, Eriko Wada, Yuko Kumagai, Shiho Takahashi, Takayuki Konno, Hiroko Kashio, Akihiko Kobayashi, Naoki Kato, Ken-Ichi Hayashi, Keisuke Fukushima, Kazuhiko Ishikawa, Kazumi Horikawa, Akira Oishi, Hidemasa Izumiya, Takahiro Ohnishi, Yoshiko Konishi, Toshiro Kuroki
This study was undertaken to determine the prevalence, antimicrobial susceptibility, and genetic relatedness of Salmonella enterica subsp. enterica and Campylobacter spp. in poultry meat, and to analyze the association of genetic types of these bacteria with their geographical distribution and antimicrobial resistance profiles. Fifty-four and 71 of 100 samples were found to be contaminated with Salmonella and Campylobacter, respectively. Nine Salmonella serotypes were found, including S. enterica subsp. enterica serovar Infantis (33%), Schwarzengrund (12%), Manhattan (9%), and others...
August 31, 2016: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/27562476/ice-vii-from-aqueous-salt-solutions-from-a-glass-to-a-crystal-with-broken-h-bonds
#18
S Klotz, K Komatsu, F Pietrucci, H Kagi, A-A Ludl, S Machida, T Hattori, A Sano-Furukawa, L E Bove
It has been known for decades that certain aqueous salt solutions of LiCl and LiBr readily form glasses when cooled to below ≈160 K. This fact has recently been exploited to produce a « salty » high-pressure ice form: When the glass is compressed at low temperatures to pressures higher than 4 GPa and subsequently warmed, it crystallizes into ice VII with the ionic species trapped inside the ice lattice. Here we report the extreme limit of salt incorporation into ice VII, using high pressure neutron diffraction and molecular dynamics simulations...
2016: Scientific Reports
https://www.readbyqxmd.com/read/27546317/studies-on-the-magnetic-ground-state-of-a-spin-m%C3%A3-bius-strip
#19
Graham N Newton, Norihisa Hoshino, Takuto Matsumoto, Takuya Shiga, Motohiro Nakano, Hiroyuki Nojiri, Wolfgang Wernsdorfer, Yuji Furukawa, Hiroki Oshio
Here we report the synthesis, structure and detailed characterisation of three n-membered oxovanadium rings, Nan [(V=O)n Nan (H2 O)n (α, β, or γ-CD)2 ]⋅m H2 O (n=6, 7, or 8), prepared by the reactions of (V=O)SO4 ⋅x H2 O with α, β, or γ-cyclodextrins (CDs) and NaOH in water. Their alternating heterometallic vanadium/sodium cyclic core structures were sandwiched between two CD moieties such that O-Na-O groups separated the neighbouring vanadyl ions. Antiferromagnetic interactions between the S=1/2 vanadyl ions led to S=0 ground states for the even-membered rings, but to two quasi-degenerate S=1/2 states for the spin-frustrated heptanuclear cluster...
September 26, 2016: Chemistry: a European Journal
https://www.readbyqxmd.com/read/27515580/erratum-partially-ordered-state-of-ice-xv
#20
K Komatsu, F Noritake, S Machida, A Sano-Furukawa, T Hattori, R Yamane, H Kagi
No abstract text is available yet for this article.
2016: Scientific Reports
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