Lee E Goldstein, Andrew M Fisher, Chad A Tagge, Xiao-Lei Zhang, Libor Velisek, John A Sullivan, Chirag Upreti, Jonathan M Kracht, Maria Ericsson, Mark W Wojnarowicz, Cezar J Goletiani, Giorgi M Maglakelidze, Noel Casey, Juliet A Moncaster, Olga Minaeva, Robert D Moir, Christopher J Nowinski, Robert A Stern, Robert C Cantu, James Geiling, Jan K Blusztajn, Benjamin L Wolozin, Tsuneya Ikezu, Thor D Stein, Andrew E Budson, Neil W Kowall, David Chargin, Andre Sharon, Sudad Saman, Garth F Hall, William C Moss, Robin O Cleveland, Rudolph E Tanzi, Patric K Stanton, Ann C McKee
Blast exposure is associated with traumatic brain injury (TBI), neuropsychiatric symptoms, and long-term cognitive disability. We examined a case series of postmortem brains from U.S. military veterans exposed to blast and/or concussive injury. We found evidence of chronic traumatic encephalopathy (CTE), a tau protein-linked neurodegenerative disease, that was similar to the CTE neuropathology observed in young amateur American football players and a professional wrestler with histories of concussive injuries...
May 16, 2012: Science Translational Medicine