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https://www.readbyqxmd.com/read/27154812/overuse-of-surgery-in-patients-with-pancreatic-cancer-a%C3%A2-nationwide-analysis-in-italy
#1
Gianpaolo Balzano, Giovanni Capretti, Giuditta Callea, Elena Cantù, Flavia Carle, Raffaele Pezzilli
BACKGROUND: According to current guidelines, pancreatic cancer patients should be strictly selected for surgery, either palliative or resective. METHODS: Population-based study, including all patients undergoing surgery for pancreatic cancer in Italy between 2010 and 2012. Hospitals were divided into five volume groups (quintiles), to search for differences among volume categories. RESULTS: There were 544 hospitals performing 10 936 pancreatic cancer operations...
May 2016: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/26998598/onset-of-inflammation-with-ischemia-implications-for-donor-lung-preservation-and-transplant-survival
#2
J-Q Tao, E M Sorokina, J P Vazquez Medina, M K Mishra, Y Yamada, J Satalin, G F Nieman, J R Nellen, B Beduhn, E Cantu, N M Habashi, W Jungraithmayr, J D Christie, S Chatterjee
Lungs stored ahead of transplant surgery experience ischemia. Pulmonary ischemia differs from ischemia in the systemic organs in that stop of blood flow in the lung leads to loss of shear alone because the lung parenchyma does not rely on blood flow for its cellular oxygen requirements. Our earlier studies on the ischemia-induced mechanosignaling cascade showed that the pulmonary endothelium responds to stop of flow by production of reactive oxygen species (ROS). We hypothesized that ROS produced in this way led to induction of proinflammatory mediators...
September 2016: American Journal of Transplantation
https://www.readbyqxmd.com/read/26880735/alterations-in-expression-of-imprinted-genes-from-the-h19-igf2-loci-in-a-multigenerational-model-of-intrauterine-growth-restriction-iugr
#3
Pablo Gonzalez-Rodriguez, Jessica Cantu, Derek O'Neil, Maxim D Seferovic, Danielle M Goodspeed, Melissa A Suter, Kjersti M Aagaard
BACKGROUND: The H19/IGF2 imprinted loci have attracted recent attention because of their role in cellular differentiation and proliferation, heritable gene regulation, and in utero or early postnatal growth and development. Expression from the imprinted H19/IGF2 locus involves a complex interplay of 3 means of epigenetic regulation: proper establishment of DNA methylation, promoter occupancy of CTCF, and expression of microRNA-675. We have demonstrated previously in a multigenerational rat model of intrauterine growth restriction the epigenetic heritability of adult metabolic syndrome in a F2 generation...
May 2016: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/26581529/-effectiveness-of-trabeculectomy-trabeculotomy-in-the-reduction-of-intraocular-pressure-in-patients-with-primary-congenital-glaucoma
#4
Rocío Azeneth Tolentino-Reyes, Daniel Garza-Cantu, Gerardo del Carmen Palacios-Saucedo
OBJECTIVE: To evaluate the effectiveness of trabeculectomy trabeculotomy in the reduction of intraocular pressure in patients with primary congenital glaucoma. MATERIAL AND METHODS: A pre-experimental before and after study was conducted with several measurements after; patients with intraocular pressure≥21 mmHg were included, of both sexes, and children under six years, which had ​​the trabeculotomy trabeculectomy. Success was defined as the reduction of intraocular pressure<21 mmHg within three months after the procedure...
November 2015: Gaceta Médica de México
https://www.readbyqxmd.com/read/26016314/-hypogastric-arteries-ligation-an-experience-in-gynecological-and-obstetric-patients-at-hospital-universitario-de-saltillo
#5
José Ignacio García de la Torre, Antonio Delgado-Rosas, Gerardo González-Cantú
BACKGROUND: Pelvic hemorrhage is a potential complication that occurs performing an obstetric or gynecological surgery, it is essential to know the distribution of pelvic vascular supplement, and implement preventive measures, can significantly reduce morbidity and mortality. OBJECTIVE: To describe the experience of hypogastric artery ligation, as a preventive and therapeutic measure of pelvic hemorrhage, this will give us new prospective lines for future investigation...
January 2015: Ginecología y Obstetricia de México
https://www.readbyqxmd.com/read/25221682/incidental-benign-metastasizing-leiomyoma-in-a-patient-with-bone-sarcoma-a-case-report
#6
Zanndor Jacob Del Real-Romo, Carlos Montero-Cantú, Oscar Villegas-Cabello, José Antonio Díaz-Elizondo, Danae Reyes-Salas, Rene Palomo-Hoil, Guillermo Peralta-Castillo, David Martínez-Sánchez, Eduardo Flores-Villalba
Background. The benign metastasizing leiomyoma is an exceptionally rare entity; it presents with ectopic leiomyoma nodules with a benign pattern. Symptoms vary according to the anatomic location. The diagnosis is histopathological, usually in patients with history of hysterectomy. Case Presentation. A 36-year-old female with 2-month history of left knee pain was diagnosed with bone fibrosarcoma. A CT scan showed pulmonary nodules. The patient started neoadjuvant chemotherapy. Conservative surgery of pelvic limb was achieved...
2014: Case Reports in Surgery
https://www.readbyqxmd.com/read/25187198/perioperative-use-of-anti-rheumatic-agents-does-not-increase-early-postoperative-infection-risks-a-veteran-affairs-administrative-database-study
#7
Zaki Abou Zahr, Andrew Spiegelman, Maria Cantu, Bernard Ng
The aim of this study was to validate a novel technique that predicts stopping of disease-modifying anti-rheumatic drugs (DMARDs) and biologic agents (BA) from the Veterans Affairs (VA) database and compare infection risks of rheumatoid arthritis patients who stopped versus continued DMARDs/BA perioperatively. We identified 6,024 patients on 1 DMARD or BA in the perioperative period between 1999 and 2009. Time gap between medication stop date and the next start date predicted drug stoppage (X). Time gap between surgery date and stop date predicted whether stoppage was before surgery (Y)...
February 2015: Rheumatology International
https://www.readbyqxmd.com/read/24854312/in-hospital-mortality-from-femoral-shaft-fracture-depends-on-the-initial-delay-to-fracture-fixation-and-injury-severity-score-a-retrospective-cohort-study-from-the-ntdb-2002-2006
#8
MULTICENTER STUDY
Robert Victor Cantu, Sara Catherine Graves, Kevin F Spratt
BACKGROUND: Optimal surgical timing for definitive treatment of femur fractures in severely injured patients remains controversial. This study was performed to examine in-hospital mortality for patients with femur fractures with regard to surgical timing, Injury Severity Score (ISS), and age. METHODS: The National Trauma Data Bank version 7.0 was used to evaluate in-hospital mortality for patients presenting with unilateral femur fractures. Patients were stratified into four groups by surgical timing (ST) and four groups by ISS...
June 2014: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/24843219/patients-survival-after-free-flap-reconstructive-surgery-of-head-and-neck-squamous-cell-carcinoma-a-retrospective-multicentre-study
#9
MULTICENTER STUDY
P Salvatori, S Paradisi, L Calabrese, A Zani, G Cantù, J Cappiello, M Benazzo, A Bozzetti, G Bellocchi, A Rinaldi Ceroni, G Succo, A Pastore, F Chiesa, S Riccio, C Piazza, A Occhini, D Sozzi, V Damiani, U Caliceti, E Crosetti, S Pelucchi, M Squadrelli Saraceno, S Podrecca
Head and neck squamous cell carcinoma of the (HNSCC) represents approximately 5% of malignant tumours in Italy. HNSCC are commonly treated with surgery or radiotherapy, or a combination of such therapies. The objectives of treatment are maximum cure rate balanced with organ preservation, restoration of form and function, reduction of morbidities and improvement or maintenance of the patient's quality of life. Immediate reconstructive surgery: local, regional or free flaps are now widely advised in the treatment of these patients...
April 2014: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/23730550/craniofacial-surgery-for-esthesioneuroblastoma-report-of-an-international-collaborative-study
#10
Snehal G Patel, Bhuvanesh Singh, Hilda E Stambuk, Diane Carlson, Patrick G Bridger, Giulio Cantu, Anthony D Cheesman, Paul Donald, Dan Fliss, Patrick Gullane, Shin-Etsu Kamata, Ivo Janecka, Luiz P Kowalski, Dennis H Kraus, Paul A Levine, Luiz R Medina, Sultan Pradhan, Victor Schramm, Carl Snyderman, William I Wei, Jatin P Shah
Introduction Impact of treatment and prognostic indicators of outcome are relatively ill-defined in esthesioneuroblastomas (ENB) because of the rarity of these tumors. This study was undertaken to assess the impact of craniofacial resection (CFR) on outcome of ENB. Patients and Methods Data on 151 patients who underwent CFR for ENB were collected from 17 institutions that participated in an international collaborative study. Patient, tumor, treatment, and outcome data were collected by questionnaires and variables were analyzed for prognostic impact on overall, disease-specific and recurrence-free survival...
June 2012: Journal of Neurological Surgery. Part B, Skull Base
https://www.readbyqxmd.com/read/23664822/uterine-sarcomas-review-of-26-years-at-the-instituto-nacional-de-cancerologia-of-mexico
#11
REVIEW
David Cantú de León, Heliodoro González, Delia Pérez Montiel, Jaime Coronel, Carlos Pérez-Plasencia, Verónica Villavicencio-Valencia, Ernesto Soto-Reyes, Luis Alonso Herrera
UNLABELLED: Uterine sarcomas are a group of uncommon tumors that account for approximately 1% of malignant neoplasms of the female genital tract and between 3 and 8.4% of malignant uterine neoplasms. OBJECTIVE: To evaluate the factors associated with the clinical behavior of uterine sarcomas. MATERIALS AND METHODS: In the period from October 1983 to December 2009, clinical files of patients with a confirmed diagnosis of uterine sarcoma at the National Institute of Cancerology of Mexico (INCan) were reviewed and evaluated...
2013: International Journal of Surgery
https://www.readbyqxmd.com/read/23650680/-third-national-ovarian-consensus-2011-grupo-de-investigaci%C3%A3-n-en-c%C3%A3-ncer-de-ovario-y-tumores-ginecol%C3%A3-gicos-de-m%C3%A3-xico-gicom
#12
Dolores Gallardo-Rincón, David Cantú-de-León, Patricia Alanís-López, Miguel Angel Alvarez-Avitia, Joel Bañuelos-Flores, Guillermo Sidney Herbert-Núñez, Luis Fernando Oñate-Ocaña, María Delia Pérez-Montiel, Amelia Rodríguez-Trejo, Eva Ruvalcaba-Limón, Alberto Serrano-Olvera, Andrea Ortega-Rojo, Patricia Cortés-Esteban, Aura Erazo-Valle, Raquel Gerson-Cwilich, Jaime De-la-Garza-Salazar, Dan Green-Renner, Eucario León-Rodríguez, Flavia Morales-Vásquez, Andrés Poveda-Velasco, José Luis Aguilar-Ponce, Luis Felipe Alva-López, Salvador Alvarado-Aguilar, Isabel Alvarado-Cabrero, Cinthia Alejandra Aquino-Mendoza, Carlos Eduardo Aranda-Flores, Artfy Bandera-Delgado, Eduardo Barragán-Curiel, Patricia Barrón-Rodríguez, Rocío Brom-Valladares, Paula Anel Cabrera-Galeana, Germán Calderillo-Ruiz, Salvador Camacho-Gutiérrez, Daniel Capdeville-García, Jesús Cárdenas-Sánchez, Elisa Carlón-Zárate, Oscar Carrillo-Garibaldi, Gerardo Castorena-Roji, Guadalupe Cervantes-Sánchez, Jaime Alberto Coronel-Martínez, José Gregorio Chanona-Vilchis, Verónica Díaz-Hernández, Pedro Escudero-de-los Ríos, Olga Garibay-Cerdenares, Eva Gómez-García, Luis Alonso Herrera-Montalvo, Luz María Hinojosa-García, David Isla-Ortiz, Josefina Jiménez-López, Arturo Javier Lavín-Lozano, Jesús Alberto Limón-Rodriguez, Horacio Noé López-Basave, Sergio César López-García, Antonio Maffuz-Aziz, Jorge Martínez-Cedillo, Dulce María Martínez-López, Juan Manuel Medina-Castro, Carlos Melo-Martínez, Carmen Méndez-Herrera, Gonzalo Montalvo-Esquivel, Miguel Angel Morales-Palomares, Andrés Morán-Mendoza, Gilberto Morgan-Villela, Aída Mota-García, David Eduardo Muñoz-González, Francisco J Ochoa-Carrillo, Maricruz Pérez-Amador, Edgar Recinos-Money, Samuel Rivera-Rivera, Juan U Robles Flores, Edith Rojas-Castillo, Carlos Rojas-Marín, Efraín Salas-Gonzáles, Liliana Sámano-Nateras, Miguel Santibañez-Andrade, Antonio Santillán-Gómez, Araceli Silva-García, Juan Alejandro Silva, Gilberto Solorza-Luna, Adán Raúl Tabarez-Ortiz, Patricia Talamás-Rohana, Laura Leticia Tirado-Gómez, Alfonso Torres-Lobatón, Félix Quijano-Castro
INTRODUCTION: Ovarian cancer (OC) is the third most common gynecologic malignancy worldwide. Most of cases it is of epithelial origin. At the present time there is not a standardized screening method, which makes difficult the early diagnosis. The 5-year survival is 90% for early stages, however most cases present at advanced stages, which have a 5-year survival of only 5-20%. GICOM collaborative group, under the auspice of different institutions, have made the following consensus in order to make recommendations for the diagnosis and management regarding to this neoplasia...
November 2011: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/23562930/head-and-neck-soft-tissue-sarcomas-prognostic-factors-and-outcome-in-a-series-of-patients-treated-at-a-single-institution
#13
D Mattavelli, R Miceli, S Radaelli, F Mattavelli, G Cantù, M Barisella, P Quattrone, S Stacchiotti, C Sangalli, P G Casali, A Gronchi, M Fiore
BACKGROUND: Head and neck soft tissue sarcomas (STS) represent a rare disease. PATIENTS AND METHODS: One hundred and sixty-seven patients underwent surgery at our institution with an eradicating intent between 1990 and 2010. Local recurrence (LR), distant metastasis (DM) and disease-specific mortality (DSM) incidence were studied along with clinicopathological prognostic factors. RESULTS: Ten-year crude cumulative incidence (CCI) of LR, DM and DSM were 19%, 11% and 26%, respectively (median follow-up 66 months)...
August 2013: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/23524776/coadjuvant-treatment-with-surgery-and-pirfenidone-in-severe-facial-trauma-due-to-dog-bite
#14
María Zulema Cantú-Cantú, Iván Lyra-González, Juan Armendáriz-Borunda
BACKGROUND: This case report assesses the effectiveness of surgery plus pirfenidone (PFD) as a concomitant therapy in the management of facial trauma after severe dog bite. METHODS: A 16-month-old female patient who suffered a severe attack by a big-sized dog (Rottweiler) in the midface area was managed with surgery/PFD combination and followed up for 20 months to evaluate the efficacy to control, prevent, and improve injury sequels. RESULTS: Surgery/PFD combination offered a good complementary therapy downregulating inflammatory activity, improving blood supply, and activating cytokine modulation and collagen synthesis/biosynthesis (scar control)...
March 2013: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/23369851/tp53-status-as-guide-for-the-management-of-ethmoid-sinus-intestinal-type-adenocarcinoma
#15
COMPARATIVE STUDY
Paolo Bossi, Federica Perrone, Rosalba Miceli, Giulio Cantù, Luigi Mariani, Ester Orlandi, Carlo Fallai, Laura D Locati, Barbara Cortelazzi, Pasquale Quattrone, Paolo Potepan, Lisa Licitra, Silvana Pilotti
OBJECTIVE: Intestinal-type adenocarcinoma (ITAC) of the ethmoid sinus is a rare, occupational-related tumor. Optimal treatment consists of surgery and radiotherapy, while chemotherapy is still investigational. The molecular profile of ITAC is characterized by the occurrence of TP53 mutations associated with genotoxic agents such as wood dust. We investigated the role of p53 functionality in relation to the primary treatment. MATERIALS AND METHODS: We retrospectively reviewed 100 medical charts of consecutive patients with a first diagnosis of ITAC treated at our Institute; 74 patients were evaluable for TP53 analysis...
May 2013: Oral Oncology
https://www.readbyqxmd.com/read/22945381/conservative-management-of-early-stage-epithelial-ovarian-cancer-results-of-a-large-retrospective-series
#16
R Fruscio, S Corso, L Ceppi, D Garavaglia, A Garbi, I Floriani, D Franchi, M G Cantù, C M Bonazzi, R Milani, C Mangioni, N Colombo
BACKGROUND: To assess the long-term oncological outcome and the fertility of young women with early-stage epithelial ovarian cancer (ES/EOC) treated with fertility-sparing surgery (FSS). PATIENTS AND METHODS: All patients treated with FSS for ES/EOC in two Italian centers were considered for this analysis. Univariate and multivariate analyses were used to test demographic characteristics and clinical features for the association with overall survival (OS), recurrence-free survival (RFS) and fertility...
January 2013: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/22916233/optimal-therapy-for-adults-with-langerhans-cell-histiocytosis-bone-lesions
#17
Maria A Cantu, Philip J Lupo, Mrinalini Bilgi, M John Hicks, Carl E Allen, Kenneth L McClain
BACKGROUND: There is little data on treatment of Langerhans cell histiocytosis (LCH) in adults. Available data is on small numbers of patients with short follow-up times and no comparison of results from different treatment regimens. We analyzed the responses of adult LCH patients with bone lesions to three primary chemotherapy treatments to define the optimal one. METHODS AND FINDINGS: Fifty-eight adult patients with bone lesions, either as a solitary site or as a component of multisystem disease, were analyzed for disease location and response to surgery, curettage, steroids, radiation, vinblastine/prednisone, 2-Chlorodeoxyadenosine (2-CdA), or cytosine arabinoside (ARA-C)...
2012: PloS One
https://www.readbyqxmd.com/read/22527901/embryo-transfer-following-in-vitro-maturation-and-cryopreservation-of-oocytes-recovered-from-antral-follicles-during-conservative-surgery-for-ovarian-cancer
#18
Rubens Fadini, Mariabeatrice Dal Canto, Mario Mignini Renzini, Rodolfo Milani, Robert Fruscio, Maria Grazia Cantù, Fausta Brambillasca, Giovanni Coticchio
No abstract text is available yet for this article.
August 2012: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/21716179/biliary-strictures-after-liver-transplantation-is-percutaneous-treatment-indicated
#19
Tullio Piardi, Michael Greget, Maxim Audet, GianFranco Calandra, Federico Gheza, Bernard Ellero, Marrie-Lorraine Woehl-Jaegle, Massimiliano Cantu, Nazario Portolani, Philippe Wolf, Patrick Pessaux
BACKGROUND: Biliary complications are common after orthotopic liver transplantation. Our study's aim is to evaluate the efficacy of percutaneous treatment of biliary strictures after orthotopic liver transplantation (OLT). MATERIAL/METHODS: Sixty-five patients with biliary anastomotic strictures received percutaneous transhepatic balloon cholangioplasty (PTBC). Three dilatations were performed with a 2- to 4-week period between the procedures. Primary and secondary patency were evaluated, with a follow-up between 6 months and 6 years...
April 2011: Annals of Transplantation: Quarterly of the Polish Transplantation Society
https://www.readbyqxmd.com/read/21573416/squamous-cell-carcinoma-of-the-upper-lip-analysis-of-123-cases
#20
L Calabrese, F Ionna, N Tradati, N Pizzi, F Mattavelli, M Greco, S Zurrida, G Cantu
Squamous cell carcinoma of the upper lip is rare and poorly described in the literature. We analysed retrospectively 123 cases occurring from 1929 to 1987. Greatest incidence was in the seventh decade and the M/F ratio was 2:1. Treatment was radiotherapy (36) or surgery (87). In early disease stages radiotherapy and surgery were equally effective, but in advanced disease surgery provided better results. Involved nodes indicate mandatory laterocervical submandibular lymph node dissection (bilateral for central lesions) but prophylactic dissection is inappropriate...
October 1993: International Journal of Oncology
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