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https://www.readbyqxmd.com/read/28204842/the-effect-of-nonsurgical-periodontal-therapy-on-hnp1-3-level-in-gingival-crevicular-fluid-of-chronic-periodontitis-patients
#1
Ewa Dolińska, Anna Skurska, Małgorzata Pietruska, Violetta Dymicka-Piekarska, Robert Milewski, Jan Pietruski, Anton Sculean
The rich bacterial flora of oral cavity is controlled by innate immune response, including antibacterial peptides and among them human neutrophil peptides 1-3 (HNP1-3). The knowledge of the involvement of HNPs in innate and acquired immunity of the periodontium is fragmentary. The aim of the study was to assess alterations in HNP1-3 levels in the gingival crevicular fluid (GCF) of chronic periodontitis patients before and after nonsurgical periodontal therapy. Nineteen patients with chronic periodontitis were qualified to the study...
February 15, 2017: Archivum Immunologiae et Therapiae Experimentalis
https://www.readbyqxmd.com/read/28194708/editorial-comment-symposium-the-3rd-annual-meeting-of-pediatric-research-in-sports-medicine-prism
#2
EDITORIAL
Matthew D Milewski, Hank G Chambers
No abstract text is available yet for this article.
February 13, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28160477/the-arachidonate-5-lipoxygenase-activating-protein-gene-polymorphism-is-associated-with-the-risk-of-scleroderma-related-interstitial-lung-disease-a-multicentre-european-scleroderma-trials-and-research-group-eustar-study
#3
Otylia Kowal-Bielecka, Sylwia Chwiesko-Minarowska, Pawel L Bernatowicz, Yannick Allanore, Timothy Radstake, Marco Matucci-Cerinic, Jasper Broen, Roger Hesselstrand, Dorota Krasowska, Gabriella Riemekasten, Madelon Vonk, Oksana Kowalczuk, Marek Bielecki, Robert Milewski, Lech Chyczewski, Jacek Niklinski, Krzysztof Kowal
No abstract text is available yet for this article.
February 4, 2017: Rheumatology
https://www.readbyqxmd.com/read/28119140/a-clinical-evaluation-of-the-efficacy-of-photodynamic-therapy-in-the-treatment-of-erosive-oral-lichen-planus-a-case-series
#4
Magdalena Sulewska, Ewa Duraj, Stefan Sobaniec, Alfreda Graczyk, Robert Milewski, Marta Wróblewska, Jan Pietruski, Małgorzata Pietruska
BACKGROUND: Erosive oral lichen planus (EOLP) poses a substantial risk of malignant transformation into squamous cell cancer. The absence of established treatment gives way to alternative therapeutic strategies, including photodynamic therapy. The aim of the study was to evaluate the efficacy of PDT in the treatment of EOLP. METHODS: Twelve female patients aged 63-80 with 22 OLP lesions (16 on the buccal mucosa, 6 on gingiva and tongue), underwent authors' own PDT scheme with the use of 5% solution of 5-aminolevulinic acid (ALA) as photosensitizer...
January 21, 2017: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/28117940/peripheral-blood-gene-expression-changes-associated-with-primary-graft-dysfunction-after-lung-transplantation
#5
J M Diamond, E Cantu, M K Porteous, Y Suzuki, K C Meyer, D J Lederer, R K Milewski, S Arcasoy, F D'Ovidio, M Bacchetta, J R Sonett, G Singh, J Costa, J W Tobias, H Rodriguez, V M Van Deerlin, K M Olthoff, A Shaked, B-L Chang, J D Christie
Recipient responses to primary graft dysfunction (PGD) after lung transplantation may have important implications to the fate of the allograft. We therefore evaluated longitudinal differences in peripheral blood gene expression in subjects with PGD. RNA expression was measured throughout the first transplant year in 106 subjects enrolled in the Clinical Trials in Organ Transplantation-03 study using a panel of 100 hypothesis-driven genes. PGD was defined as grade 3 in the first 72 posttransplant hours. Eighteen genes were differentially expressed over the first year based on PGD development, with significant representation from innate and adaptive immunity genes, with most differences identified very early after transplant...
January 24, 2017: American Journal of Transplantation
https://www.readbyqxmd.com/read/28099101/myeloperoxidase-nuclear-imaging-for-epileptogenesis
#6
Yinian Zhang, Daniel P Seeburg, Benjamin Pulli, Gregory R Wojtkiewicz, Lionel Bure, Wendy Atkinson, Stefan Schob, Yoshiko Iwamoto, Muhammad Ali, Wei Zhang, Elisenda Rodriguez, Andrew Milewski, Edmund J Keliher, Cuihua Wang, Yawen Pan, Filip K Swirski, John W Chen
No abstract text is available yet for this article.
February 2017: Radiology
https://www.readbyqxmd.com/read/28090010/long-term-outcomes-after-percutaneous-lower-extremity-arterial-interventions-with-atherectomy-vs-balloon-angioplasty%C3%A3-propensity-score-matched-registry
#7
Adam Janas, Piotr P Buszman, Krzysztof P Milewski, Szymon Wiernek, Ksenia Janas, Maciej Pruski, Wojciech Wojakowski, Aleksandra Błachut, Wojciech Picheta, Pawel Buszman, Stefan Kiesz
BACKGROUND: The impact of endovascular revascularization of the lower extremity arteries with atherectomy (AT) compared with percutaneous transluminal angioplasty (PTA) is still unclear. Therefore, the aim of the study was to compare long-term outcomes after percutaneous PTA and AT in patients requiring endovascular revascularization.Methods and Results:This was a single-center, retrospective registry of obstructive and symptomatic PAD patients who underwent endovascular revascularization...
January 14, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/28067591/association-between-vitamin-d-receptor-polymorphism-and-serum-vitamin-d-levels-in-children-with-low-energy-fractures
#8
Michal Karpiński, Anna Galicka, Robert Milewski, Janusz Popko, Vladimir Badmaev, Sidney J Stohs
OBJECTIVE: Fractures of bones, especially forearm fractures, are very common in children and their number is increasing. This study was designed to determine the impact of vitamin D serum levels and vitamin D receptor (VDR) polymorphisms on the occurrence of low-energy fractures in children. METHODS: The study group consisted of 100 children with clinically relevant bone fractures and a control group consisted of 127 children without fractures. Total vitamin D [25(OH)D3 plus 25(OH)D2] serum concentrations were evaluated in every patient...
January 9, 2017: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/28043359/aberrant-effects-of-altrenogest-and-exposure-to-exogenous-gonadotropins-on-follicular-cysts-appearance-in-gilts
#9
A J Ziecik, J Klos, E Przygrodzka, R Milewski, B Jana
Research was conducted to determine the effect of altrenogest and exposure to exogenous gonadotropins on ovarian function in prepubertal and mature gilts. Crossbred, presumably sexually mature gilts (n = 51), were fed with altrenogest for 18 consecutive days and the day after the last feeding with altrenogest, gilts were treated with eCG and 72 hours later challenged with hCG. Animals were slaughtered on Days 10 to 13 of their gonadotropins synchronized estrous cycle. Ovaries were examined for the number of CL, number of follicular cysts, and presence of corpora albicantia...
February 2017: Theriogenology
https://www.readbyqxmd.com/read/28019051/remote-supervision-to-decrease-hospitalization-rate-unified-and-integrated-platform-for-data-collected-from-devices-manufactured-by-different-companies-design-and-rationale-of-the-result-study
#10
Mateusz Tajstra, Adam Sokal, Arkadiusz Gwóźdź, Marcin Wilczek, Adam Gacek, Konrad Wojciechowski, Elżbieta Gadula-Gacek, Elżbieta Adamowicz-Czoch, Katarzyna Chłosta-Niepiekło, Krzysztof Milewski, Piotr Rozentryt, Zbigniew Kalarus, Mariusz Gąsior, Lech Poloński
The number of patients with heart failure implantable cardiac electronic devices (CIEDs) is growing. Hospitalization rate in this group is very high and generates enormous costs. To avoid the need for hospital treatment, optimized monitoring and follow-up is crucial. Remote monitoring (RM) has been widely put into practice in the management of CIEDs but it may be difficult due to the presence of differences in systems provided by device manufacturers and loss of gathered data in case of device reimplantation...
December 25, 2016: Annals of Noninvasive Electrocardiology
https://www.readbyqxmd.com/read/27976797/comparable-vascular-response-of-a-new-generation-sirolimus-eluting-stents-when-compared-to-fluoropolymer-everolimus-eluting-stents-in-the-porcine-coronary-restenosis-model
#11
Piotr P Buszman, Magdalena J Michalak, Maciej Pruski, Carlos Fernandez, Michał Jelonek, Adam Janas, Claudine Savard, Beata Gwiazdowska-Nowotka, Aleksander Żurakowski, Wojciech Wojakowski, Paweł E Buszman, Krzysztof Milewski
BACKGROUND: Novel sirolimus eluting stents (SES) have shown non-inferior clinical outcomes when compared to everolimus eluting stents (EES), however only limited preclinical data have been published. Therefore, we evaluate vascular response of a new generation biodegradable polymer SES (BP-SES: Alex Plus, Balton) and fluoropolymer EES (EES: Xience Pro, Abbott) in the porcine coronary restenosis model. METHODS: A total of 40 stents were implanted with 120% overstretch in coronaries of 17 domestic swine: 16 BP-SES, 16 EES and 8 bare metal controls (BMS)...
2016: Cardiology Journal
https://www.readbyqxmd.com/read/27970228/tct-837-comparable-vascular-response-of-a-new-generation-sirolimus-eluting-stents-when-compared-to-fluoropolymer-everolimus-eluting-stents-in-the-porcine-coronary-restenosis-model
#12
Piotr Buszman, Magdalena Michalak, Maciej Pruski, Michał Jelonek, Adam Janas, Aleksander Żurakowski, Beata Gwiazdowska-Nowotka, Wojtek Wojakowski, Paweł Buszman, Krzysztof Milewski
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27970192/tct-803-long-term-outcomes-in-diabetic-patients-treated-with-atherectomy-for-peripheral-artery-disease
#13
Adam Janas, Piotr Buszman, Krzysztof Milewski, Marek Król, Wojciech Fil, Wojtek Wojakowski, Przemek Nowakowski, Aleksandra Blachut, Maciej Pruski, Pawel Buszman, R Stefan Kiesz
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27958618/morphokinetic-parameters-as-a-source-of-information-concerning-embryo-developmental-and-implantation-potential
#14
Robert Milewski, Jan Czerniecki, Agnieszka Kuczyńska, Bożena Stankiewicz, Waldemar Kuczyński
OBJECTIVES: The aim of the study was to present the results of time-lapse observation and to verify whether morphokinetic parameters are associated with embryo developmental and implantation potential. MATERIAL AND METHODS: The analysed data concern the development of 1,060 embryos, 898 of which (84.72%) achieved the blastocyst stage and 307 were transferred into the uterine cavity. As a result, 126 (41.04%) biochemical pregnancies and 109 (35.50%) clinical pregnancies were observed...
2016: Ginekologia Polska
https://www.readbyqxmd.com/read/27885576/asymmetric-dimethylarginine-and-hepatic-encephalopathy-cause-effect-or-association
#15
Anna Czarnecka, Krzysztof Milewski, Magdalena Zielińska
The methylated derivative of L-arginine, asymmetric dimethylarginine (ADMA) is synthesized in different mammalian tissues including the brain. ADMA acts as an endogenous, nonselective, competitive inhibitor of all three isoforms of nitric oxide synthase (NOS) and may limit L-arginine supply from the plasma to the enzyme via reducing its transport by cationic amino acid transporters. Hepatic encephalopathy (HE) is a relatively frequently diagnosed complex neuropsychiatric syndrome associated with acute or chronic liver failure, characterized by symptoms linked with impaired brain function leading to neurological disabilities...
November 25, 2016: Neurochemical Research
https://www.readbyqxmd.com/read/27812233/new-hybrid-pectin-based-biosorbents
#16
Agata Jakóbik-Kolon, Andrzej K Milewski, Krzysztof Karoń, Joanna Bok-Badura
In this work hybrid pectin-based biosorbents with secondary polysaccharide additives (gellan, carob and xanthan gum, ratio to pectin 1:1, 1:1 and 1:3, respectively) were obtained at two temperatures. The presence of these additives in prepared beads was confirmed by Raman spectra. The SEM micrographs show better homogeneity of blends and grater differences between structures of beads with various additives obtained at higher temperature. The sorption capacity of our hybrid biosorbents as well as sole pectin sorbent is rather the same, and equals 0...
November 1, 2016: Separation Science and Technology
https://www.readbyqxmd.com/read/27798791/anterolateral-ligament-of-the-knee-shows-variable-anatomy-in-pediatric-specimens
#17
Kevin G Shea, Matthew D Milewski, Peter C Cannamela, Theodore J Ganley, Peter D Fabricant, Elizabeth B Terhune, Alexandra C Styhl, Allen F Anderson, John D Polousky
BACKGROUND: Anterior cruciate ligament (ACL) reconstruction failure rates are highest in youth athletes. The role of the anterolateral ligament in rotational knee stability is of increasing interest, and several centers are exploring combined ACL and anterolateral ligament reconstruction for these young patients. Literature on the anterolateral ligament of the knee is sparse in regard to the pediatric population. A single study on specimens younger than age 5 years demonstrated the presence of the anterolateral ligament in only one of eight specimens; therefore, much about the prevalence and anatomy of the anterolateral ligament in pediatric specimens remains unknown...
October 31, 2016: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/27793802/a-sequence-upstream-of-canonical-pdz-binding-motif-within-cftr-cooh-terminus-enhances-nherf1-interaction
#18
Neeraj Sharma, Jessica LaRusch, Patrick R Sosnay, Laura B Gottschalk, Andrea P Lopez, Matthew J Pellicore, Taylor Evans, Emily Davis, Melis Atalar, Chan-Hyun Na, Gedge D Rosson, Deborah Belchis, Michal Milewski, Akhilesh Pandey, Garry R Cutting
The development of cystic fibrosis transmembrane conductance regulator (CFTR) targeted therapy for cystic fibrosis has generated interest in maximizing membrane residence of mutant forms of CFTR by manipulating interactions with scaffold proteins, such as sodium/hydrogen exchange regulatory factor-1 (NHERF1). In this study, we explored whether COOH-terminal sequences in CFTR beyond the PDZ-binding motif influence its interaction with NHERF1. NHERF1 displayed minimal self-association in blot overlays (NHERF1, Kd = 1,382 ± 61...
December 1, 2016: American Journal of Physiology. Lung Cellular and Molecular Physiology
https://www.readbyqxmd.com/read/27776368/erratum-research-in-osteochondritis-dissecans-of-the-knee-2016-update
#19
Jeffrey J Nepple, Matthew D Milewski, Kevin G Shea
No abstract text is available yet for this article.
November 2016: Journal of Knee Surgery
https://www.readbyqxmd.com/read/27738667/how-short-rnas-impact-the-human-ribonuclease-dicer-activity-putative-regulatory-feedback-loops-and-other-rna-mediated-mechanisms-controlling-microrna-processing
#20
Natalia Koralewska, Weronika Hoffmann, Maria Pokornowska, Marek Milewski, Andrea Lipinska, Krystyna Bienkowska-Szewczyk, Marek Figlerowicz, Anna Kurzynska-Kokorniak
Ribonuclease Dicer plays a pivotal role in RNA interference pathways by processing long double-stranded RNAs and single-stranded hairpin RNA precursors into small interfering RNAs (siRNAs) and microRNAs (miRNAs), respectively. While details of Dicer regulation by a variety of proteins are being elucidated, less is known about non-protein factors, e.g. RNA molecules, that may influence this enzyme's activity. Therefore, we decided to investigate the question of whether the RNA molecules can function not only as Dicer substrates but also as its regulators...
2016: Acta Biochimica Polonica
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