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JOURNAL ARTICLE
Hao Liu, Michael Sacks, Natalie T Simonian, Joseph Gorman, Robert Gorman
Development of patient specific models of LV-MV interactions in ischemic mitral regurgitation (IMR) are complicated by the substantial variability and complex etiologies, making it difficult to extract underlying mechanisms. We thus developed a detailed ovine LV-MV finite element model based for the normal and acute post-MI states. The ovine LV FEM model was first extended to incorporate a detailed MV leaflet sub-model with a functionally-equivalent CT structure. The resulting complete LV-MV model was first used to simulate the full cardiac cycle in the normal state to establish baseline responses...
April 23, 2024: Journal of Biomechanical Engineering
#2
JOURNAL ARTICLE
Richmond Yeboah, Richmond Gorman, Henry Kyeremateng Acheampong, Emmanuella Nyarko-Afriyie, Sherihane Aryeetey, Henrietta Dede Tetteh, Michael Owusu, Eric Smart Yeboah, Titus Adade, Joseph Bonney, Yaw Ampem Amoako, Philip El-Duah, Kwasi Obiri-Danso, Christian Drosten, Richard Odame Phillips, Augustina Angelina Sylverken
Viral encephalitis is a rare, yet severe neurological disorder. It poses a significant public health threat due to its high morbidity and mortality. Despite the disproportionate burden of the disease in impoverished African countries, the true extent of the problem remains elusive due to the scarcity of accurate diagnostic methods. The absence of timely and effective diagnostic tools, particularly Real-time Polymerase Chain Reaction, has led to misguided treatment, and an underestimation of the disease burden in Ghana...
2024: PloS One
#3
JOURNAL ARTICLE
Shaynna N Herrera, Cansu Sarac, Shreya A Vaidya, Sophia Shuster, Romi Lyallpuri, Matthew F Dobbs, Jane Gorman, Antigone Phili, Alessia Mcgowan, Storm Portner, Maxwell Mikelic, Rachel Jespersen, Joseph S Deluca, Kayla Y Lim, Lawrence H Yang, Katarzyna Wyka, Yulia Landa, Cheryl M Corcoran
Individuals at clinical high risk for psychosis (CHR) report a strong desire for psychoeducation, and clinical guidelines recommend psychoeducation in early psychosis care. Although several CHR psychoeducation models have been developed, additional research is needed to establish the effectiveness of these models. The goal of this study was to conduct a pilot trial of the Brief Educational Guide for Individuals in Need (BEGIN). BEGIN is a brief structured psychoeducation intervention designed to educate CHR individuals on symptoms and treatment options...
February 8, 2024: Psychological Services
#4
JOURNAL ARTICLE
Natalie T Simonian, Hao Liu, Sneha Vakamudi, Mark J Pirwitz, Alison M Pouch, Joseph H Gorman, Robert C Gorman, Michael S Sacks
PURPOSE: Mitral regurgitation (MR) is a highly prevalent and deadly cardiac disease characterized by improper mitral valve (MV) leaflet coaptation. Among the plethora of available treatment strategies, the MitraClip is an especially safe option, but optimizing its long-term efficacy remains an urgent challenge. METHODS: We applied our noninvasive image-based strain computation pipeline [1] to intraoperative transesophageal echocardiography datasets taken from ten patients undergoing MitraClip repair, spanning a range of MR etiologies and MitraClip configurations...
September 5, 2023: Cardiovascular Engineering and Technology
#5
REVIEW
Michelle L Blakely, Elias B Chahine, Roshni P Emmons, Emily F Gorman, Kevin N Astle, Jay L Martello, T Joseph Mattingly Ii, Anna Nogid, Amy Pick, Anandi V Law
OBJECTIVES: The 2020-2021 American Association of Colleges of Pharmacy Faculty Affairs Standing Committee (FASC) was charged with identifying how faculty can self-advocate and promote themselves in a social influence context. FINDINGS: The FASC identified social influence and persuasion theories and strategies that can be used by faculty to initiate self-advocacy discussions and collaborations. Social influence and persuasion theories can provide a framework for research and scholarship or for beginning discussions regarding self-advocacy...
August 2023: American Journal of Pharmaceutical Education
#6
JOURNAL ARTICLE
Hao Liu, Natalie T Simonian, Alison Pouch, Paul Iaizzo, Joseph Gorman, Robert Gorman, Michael Sacks
In the present work, we established a patient-specific mitral valve (MV) computational pipeline based strictly on standard-of-care preoperative imaging data to quantitatively predict the post-repair MV functional state. First, we developed a finite-element model of the full patient-specific MV apparatus by quantifying the MV chordae tendinae (MVCT) distributions from five CT-imaged excised human hearts and segmenting the MV leaflet geometry and identifiable MVCT origins from three patients' preoperative 3D echocardiography images...
June 29, 2023: Journal of Biomechanical Engineering
#7
JOURNAL ARTICLE
Emily R Edwards, Brettland Coolidge, Danny Ruiz, Gabriella Epshteyn, Alison Krauss, Daniel Gorman, Brigid Connelly, Clare Redden, Paul El-Meouchy, Joseph Geraci
INTRODUCTION: Prevention of suicide-related behaviors is considered a top clinical priority within the Departments of Veterans Affairs and Defense. Despite previous literature attesting to the likely importance of situational stress as a key correlate of acute changes in suicide risk, longitudinal research into associations between situational stress and suicide-related outcomes among military personnel has been relatively limited. METHODS: The current study examined associations between situational stress, recent suicide attempt, and future suicide attempt using data from 14,508 Army soldiers and recently discharged veterans enrolled in the Army Study to Assess Risk and Resilience in Servicemembers-Longitudinal Studies (STARRS-LS)...
June 12, 2023: Suicide & Life-threatening Behavior
#8
JOURNAL ARTICLE
Ankush Aggarwal, Peter Mortensen, Jilei Hao, Łukasz Kaczmarczyk, Albert T Cheung, Lourdes Al Ghofaily, Robert C Gorman, Nimesh D Desai, Joseph E Bavaria, Alison M Pouch
Even though the central role of mechanics in the cardiovascular system is widely recognized, estimating mechanical deformation and strains in-vivo remains an ongoing practical challenge. Herein, we present a semi-automated framework to estimate strains from four-dimensional (4D) echocardiographic images and apply it to the aortic roots of patients with normal trileaflet aortic valves (TAV) and congenital bicuspid aortic valves (BAV). The method is based on fully nonlinear shell-based kinematics, which divides the strains into in-plane (shear and dilatational) and out-of-plane components...
April 1, 2023: Medical Image Analysis
#9
JOURNAL ARTICLE
Chi D L Nguyen, Aura Cecilia Jimenez-Moreno, Monika Merker, Charles Joseph Bowers, Nikoletta Nikolenko, Andreas Hentschel, Thomas Müntefering, Angus Isham, Tobias Ruck, Matthias Vorgerd, Vera Dobelmann, Genevieve Gourdon, Ulrike Schara-Schmidt, Andrea Gangfuss, Charlotte Schröder, Albert Sickmann, Claudia Gross, Grainne Gorman, Werner Stenzel, Laxmikanth Kollipara, Denisa Hathazi, Sally Spendiff, Cynthia Gagnon, Corinna Preusse, Elise Duchesne, Hanns Lochmüller, Andreas Roos
BACKGROUND AND PURPOSE: Myotonic dystrophy type 1 (DM1) is the most common form of adult-onset muscular dystrophy and is caused by an repeat expansion [r(CUG)exp ] located in the 3' untranslated region of the DMPK gene. Symptoms include skeletal and cardiac muscle dysfunction and fibrosis. In DM1, there is a lack of established biomarkers in routine clinical practice. Thus, we aimed to identify a blood biomarker with relevance for DM1-pathophysiology and clinical presentation. METHODS: We collected fibroblasts from 11, skeletal muscles from 27, and blood samples from 158 DM1 patients...
March 9, 2023: Journal of Neurology
#10
JOURNAL ARTICLE
Kai-Wen K Yang, Chloé F Paris, Kevin T Gorman, Ilia Rattsev, Rebecca H Yoo, Yijia Chen, Jacob M Desman, Tony Y Wei, Joseph L Greenstein, Casey Overby Taylor, Stuart C Ray
There have been over 621 million cases of COVID-19 worldwide with over 6.5 million deaths. Despite the high secondary attack rate of COVID-19 in shared households, some exposed individuals do not contract the virus. In addition, little is known about whether the occurrence of COVID-19 resistance differs among people by health characteristics as stored in the electronic health records (EHR). In this retrospective analysis, we develop a statistical model to predict COVID-19 resistance in 8,536 individuals with prior COVID-19 exposure using demographics, diagnostic codes, outpatient medication orders, and count of Elixhauser comorbidities in EHR data from the COVID-19 Precision Medicine Platform Registry...
2023: PloS One
#11
REVIEW
Shaynna N Herrera, Cansu Sarac, Antigone Phili, Jane Gorman, Lily Martin, Romi Lyallpuri, Matthew F Dobbs, Joseph S DeLuca, Kim T Mueser, Katarzyna E Wyka, Lawrence H Yang, Yulia Landa, Cheryl M Corcoran
Psychoeducation is recommended in the treatment of patients with schizophrenia and has been shown to improve satisfaction with mental health service and treatment adherence, reduce relapse and hospital readmission rates, and enhance functioning and quality of life. Youth at clinical high risk for psychosis (CHR) may also benefit from receiving psychoeducation as part of their treatment. The goal of this study was to conduct a scoping review to map out the existing literature on psychoeducation for CHR individuals, including content, utilization, and benefits, in order to identify areas for future research and clinical care...
January 16, 2023: Schizophrenia Research
#12
JOURNAL ARTICLE
Natalie T Simonian, Hao Liu, Alison M Pouch, Joseph H Gorman, Robert C Gorman, Michael S Sacks
OBJECTIVES: Long-term outcomes of mitral valve repair procedures to correct ischemic mitral regurgitation remain unpredictable, due to an incomplete understanding of the disease process and the inability to reliably quantify the coaptation zone using echocardiography. Our objective was to quantify patient-specific mitral valve coaptation behavior from clinical echocardiographic images obtained before and after repair to assess coaptation restoration and its relationship with long-term repair durability...
December 2022: JTCVS techniques
#13
JOURNAL ARTICLE
Paul J White, Clare Guilding, Tom Angelo, John P Kelly, Laurel Gorman, Steven J Tucker, Ashleigh Fun, Jae Han, Guanliang Chen, Yassmin Samak, Anna-Marie Babey, Fabiana A Caetano, Sudhir Chandra Sarangi, Jennifer Koenig, Haiping Hao, Joseph Goldfarb, Kelly Karpa, Luciene Vieira, Carolina Restini, Margaret Cunningham, Patrik Aronsson, Roisin Kelly-Laubscher, Mark Hernandez, Patangi K Rangachari, Janet Mifsud, Fatima Mraiche, Ramzi Sabra, Octavio Piñeros, Xuechu Zhen, Helen Kwanashie, Betty Exintaris, Nilushi Karunaratne, Kuniaki Ishii, Yannee Liu
BACKGROUND AND PURPOSE: In recent decades, a focus on the most critical and fundamental concepts has proven highly advantageous to students and educators in many science disciplines. Pharmacology, unlike microbiology, biochemistry, or physiology, lacks a consensus list of such core concepts. EXPERIMENTAL APPROACH: We sought to develop a research-based, globally relevant list of core concepts that all students completing a foundational pharmacology course should master...
May 2023: British Journal of Pharmacology
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JOURNAL ARTICLE
Yuwaraj Kadariya, Eleonora Sementino, Ujjawal Shrestha, Greg Gorman, Jonathan M White, Eric A Ross, Margie L Clapper, Nouri Neamati, Mark Steven Miller, Joseph R Testa
Malignant mesothelioma (MM) is an incurable cancer of the serosal lining that is often caused by exposure to asbestos. Therefore, novel agents for the prevention and treatment of this disease are urgently needed. Asbestos induces the release of pro-inflammatory cytokines such as IL-1β and IL-6, which play a role in MM development. IL-6 is a component of the JAK-STAT3 pathway that contributes to inflammation-associated tumorigenesis. Glycoprotein 130 (gp130), the signal transducer of this signaling axis, is an attractive drug target because of its role in promoting neoplasia via the activation of downstream STAT3 signaling...
November 10, 2022: Carcinogenesis
#15
JOURNAL ARTICLE
Bruno V Rego, Amir H Khalighi, Eric K Lai, Robert C Gorman, Joseph H Gorman, Michael S Sacks
Each year, more than 40,000 people undergo mitral valve (MV) repair surgery domestically to treat regurgitation caused by myocardial infarction (MI). Although continual MV tissue remodelling following repair is believed to be a major contributor to regurgitation recurrence, the effects of the post-MI state on MV remodelling remain poorly understood. This lack of understanding limits our ability to predict the remodelling of the MV both post-MI and post-surgery to facilitate surgical planning. As a necessary first step, the present study was undertaken to noninvasively quantify the effects of MI on MV remodelling in terms of leaflet geometry and deformation...
October 26, 2022: Scientific Reports
#16
JOURNAL ARTICLE
Houriiyah Tegally, James E San, Matthew Cotten, Monika Moir, Bryan Tegomoh, Gerald Mboowa, Darren P Martin, Cheryl Baxter, Arnold W Lambisia, Amadou Diallo, Daniel G Amoako, Moussa M Diagne, Abay Sisay, Abdel-Rahman N Zekri, Abdou Salam Gueye, Abdoul K Sangare, Abdoul-Salam Ouedraogo, Abdourahmane Sow, Abdualmoniem O Musa, Abdul K Sesay, Abe G Abias, Adam I Elzagheid, Adamou Lagare, Adedotun-Sulaiman Kemi, Aden Elmi Abar, Adeniji A Johnson, Adeola Fowotade, Adeyemi O Oluwapelumi, Adrienne A Amuri, Agnes Juru, Ahmed Kandeil, Ahmed Mostafa, Ahmed Rebai, Ahmed Sayed, Akano Kazeem, Aladje Balde, Alan Christoffels, Alexander J Trotter, Allan Campbell, Alpha K Keita, Amadou Kone, Amal Bouzid, Amal Souissi, Ambrose Agweyu, Amel Naguib, Ana V Gutierrez, Anatole Nkeshimana, Andrew J Page, Anges Yadouleton, Anika Vinze, Anise N Happi, Anissa Chouikha, Arash Iranzadeh, Arisha Maharaj, Armel L Batchi-Bouyou, Arshad Ismail, Augustina A Sylverken, Augustine Goba, Ayoade Femi, Ayotunde E Sijuwola, Baba Marycelin, Babatunde L Salako, Bamidele S Oderinde, Bankole Bolajoko, Bassirou Diarra, Belinda L Herring, Benjamin Tsofa, Bernard Lekana-Douki, Bernard Mvula, Berthe-Marie Njanpop-Lafourcade, Blessing T Marondera, Bouh Abdi Khaireh, Bourema Kouriba, Bright Adu, Brigitte Pool, Bronwyn McInnis, Cara Brook, Carolyn Williamson, Cassien Nduwimana, Catherine Anscombe, Catherine B Pratt, Cathrine Scheepers, Chantal G Akoua-Koffi, Charles N Agoti, Chastel M Mapanguy, Cheikh Loucoubar, Chika K Onwuamah, Chikwe Ihekweazu, Christian N Malaka, Christophe Peyrefitte, Chukwa Grace, Chukwuma E Omoruyi, Clotaire D Rafaï, Collins M Morang'a, Cyril Erameh, Daniel B Lule, Daniel J Bridges, Daniel Mukadi-Bamuleka, Danny Park, David A Rasmussen, David Baker, David J Nokes, Deogratius Ssemwanga, Derek Tshiabuila, Dominic S Y Amuzu, Dominique Goedhals, Donald S Grant, Donwilliams O Omuoyo, Dorcas Maruapula, Dorcas W Wanjohi, Ebenezer Foster-Nyarko, Eddy K Lusamaki, Edgar Simulundu, Edidah M Ong'era, Edith N Ngabana, Edward O Abworo, Edward Otieno, Edwin Shumba, Edwine Barasa, El Bara Ahmed, Elhadi A Ahmed, Emmanuel Lokilo, Enatha Mukantwari, Eromon Philomena, Essia Belarbi, Etienne Simon-Loriere, Etilé A Anoh, Eusebio Manuel, Fabian Leendertz, Fahn M Taweh, Fares Wasfi, Fatma Abdelmoula, Faustinos T Takawira, Fawzi Derrar, Fehintola V Ajogbasile, Florette Treurnicht, Folarin Onikepe, Francine Ntoumi, Francisca M Muyembe, Frank E Z Ragomzingba, Fred A Dratibi, Fred-Akintunwa Iyanu, Gabriel K Mbunsu, Gaetan Thilliez, Gemma L Kay, George O Akpede, Gert U van Zyl, Gordon A Awandare, Grace S Kpeli, Grit Schubert, Gugu P Maphalala, Hafaliana C Ranaivoson, Hannah E Omunakwe, Harris Onywera, Haruka Abe, Hela Karray, Hellen Nansumba, Henda Triki, Herve Albéric Adje Kadjo, Hesham Elgahzaly, Hlanai Gumbo, Hota Mathieu, Hugo Kavunga-Membo, Ibtihel Smeti, Idowu B Olawoye, Ifedayo M O Adetifa, Ikponmwosa Odia, Ilhem Boutiba Ben Boubaker, Iluoreh Ahmed Mohammad, Isaac Ssewanyana, Isatta Wurie, Iyaloo S Konstantinus, Jacqueline Wemboo Afiwa Halatoko, James Ayei, Janaki Sonoo, Jean-Claude C Makangara, Jean-Jacques M Tamfum, Jean-Michel Heraud, Jeffrey G Shaffer, Jennifer Giandhari, Jennifer Musyoki, Jerome Nkurunziza, Jessica N Uwanibe, Jinal N Bhiman, Jiro Yasuda, Joana Morais, Jocelyn Kiconco, John D Sandi, John Huddleston, John K Odoom, John M Morobe, John O Gyapong, John T Kayiwa, Johnson C Okolie, Joicymara S Xavier, Jones Gyamfi, Joseph F Wamala, Joseph H K Bonney, Joseph Nyandwi, Josie Everatt, Joweria Nakaseegu, Joyce M Ngoi, Joyce Namulondo, Judith U Oguzie, Julia C Andeko, Julius J Lutwama, Juma J H Mogga, Justin O'Grady, Katherine J Siddle, Kathleen Victoir, Kayode T Adeyemi, Kefentse A Tumedi, Kevin S Carvalho, Khadija Said Mohammed, Koussay Dellagi, Kunda G Musonda, Kwabena O Duedu, Lamia Fki-Berrajah, Lavanya Singh, Lenora M Kepler, Leon Biscornet, Leonardo de Oliveira Martins, Lucious Chabuka, Luicer Olubayo, Lul Deng Ojok, Lul Lojok Deng, Lynette I Ochola-Oyier, Lynn Tyers, Madisa Mine, Magalutcheemee Ramuth, Maha Mastouri, Mahmoud ElHefnawi, Maimouna Mbanne, Maitshwarelo I Matsheka, Malebogo Kebabonye, Mamadou Diop, Mambu Momoh, Maria da Luz Lima Mendonça, Marietjie Venter, Marietou F Paye, Martin Faye, Martin M Nyaga, Mathabo Mareka, Matoke-Muhia Damaris, Maureen W Mburu, Maximillian G Mpina, Michael Owusu, Michael R Wiley, Mirabeau Y Tatfeng, Mitoha Ondo'o Ayekaba, Mohamed Abouelhoda, Mohamed Amine Beloufa, Mohamed G Seadawy, Mohamed K Khalifa, Mooko Marethabile Matobo, Mouhamed Kane, Mounerou Salou, Mphaphi B Mbulawa, Mulenga Mwenda, Mushal Allam, My V T Phan, Nabil Abid, Nadine Rujeni, Nadir Abuzaid, Nalia Ismael, Nancy Elguindy, Ndeye Marieme Top, Ndongo Dia, Nédio Mabunda, Nei-Yuan Hsiao, Nelson Boricó Silochi, Ngiambudulu M Francisco, Ngonda Saasa, Nicholas Bbosa, Nickson Murunga, Nicksy Gumede, Nicole Wolter, Nikita Sitharam, Nnaemeka Ndodo, Nnennaya A Ajayi, Noël Tordo, Nokuzola Mbhele, Norosoa H Razanajatovo, Nosamiefan Iguosadolo, Nwando Mba, Ojide C Kingsley, Okogbenin Sylvanus, Oladiji Femi, Olubusuyi M Adewumi, Olumade Testimony, Olusola A Ogunsanya, Oluwatosin Fakayode, Onwe E Ogah, Ope-Ewe Oludayo, Ousmane Faye, Pamela Smith-Lawrence, Pascale Ondoa, Patrice Combe, Patricia Nabisubi, Patrick Semanda, Paul E Oluniyi, Paulo Arnaldo, Peter Kojo Quashie, Peter O Okokhere, Philip Bejon, Philippe Dussart, Phillip A Bester, Placide K Mbala, Pontiano Kaleebu, Priscilla Abechi, Rabeh El-Shesheny, Rageema Joseph, Ramy Karam Aziz, René G Essomba, Reuben Ayivor-Djanie, Richard Njouom, Richard O Phillips, Richmond Gorman, Robert A Kingsley, Rosa Maria D E S A Neto Rodrigues, Rosemary A Audu, Rosina A A Carr, Saba Gargouri, Saber Masmoudi, Sacha Bootsma, Safietou Sankhe, Sahra Isse Mohamed, Saibu Femi, Salma Mhalla, Salome Hosch, Samar Kamal Kassim, Samar Metha, Sameh Trabelsi, Sara Hassan Agwa, Sarah Wambui Mwangi, Seydou Doumbia, Sheila Makiala-Mandanda, Sherihane Aryeetey, Shymaa S Ahmed, Side Mohamed Ahmed, Siham Elhamoumi, Sikhulile Moyo, Silvia Lutucuta, Simani Gaseitsiwe, Simbirie Jalloh, Soa Fy Andriamandimby, Sobajo Oguntope, Solène Grayo, Sonia Lekana-Douki, Sophie Prosolek, Soumeya Ouangraoua, Stephanie van Wyk, Stephen F Schaffner, Stephen Kanyerezi, Steve Ahuka-Mundeke, Steven Rudder, Sureshnee Pillay, Susan Nabadda, Sylvie Behillil, Sylvie L Budiaki, Sylvie van der Werf, Tapfumanei Mashe, Thabo Mohale, Thanh Le-Viet, Thirumalaisamy P Velavan, Tobias Schindler, Tongai G Maponga, Trevor Bedford, Ugochukwu J Anyaneji, Ugwu Chinedu, Upasana Ramphal, Uwem E George, Vincent Enouf, Vishvanath Nene, Vivianne Gorova, Wael H Roshdy, Wasim Abdul Karim, William K Ampofo, Wolfgang Preiser, Wonderful T Choga, Yahaya Ali Ahmed, Yajna Ramphal, Yaw Bediako, Yeshnee Naidoo, Yvan Butera, Zaydah R de Laurent, Ahmed E O Ouma, Anne von Gottberg, George Githinji, Matshidiso Moeti, Oyewale Tomori, Pardis C Sabeti, Amadou A Sall, Samuel O Oyola, Yenew K Tebeje, Sofonias K Tessema, Tulio de Oliveira, Christian Happi, Richard Lessells, John Nkengasong, Eduan Wilkinson
Investment in SARS-CoV-2 sequencing in Africa over the past year has led to a major increase in the number of sequences generated, now exceeding 100,000 genomes, used to track the pandemic on the continent. Our results show an increase in the number of African countries able to sequence domestically, and highlight that local sequencing enables faster turnaround time and more regular routine surveillance. Despite limitations of low testing proportions, findings from this genomic surveillance study underscore the heterogeneous nature of the pandemic and shed light on the distinct dispersal dynamics of Variants of Concern, particularly Alpha, Beta, Delta, and Omicron, on the continent...
September 15, 2022: Science
#17
Cholsoon Jang, Sheng Hui, Xianfeng Zeng, Alexis J Cowan, Lin Wang, Li Chen, Raphael J Morscher, Jorge Reyes, Christian Frezza, Ho Young Hwang, Akito Imai, Yoshiaki Saito, Keitaro Okamoto, Christine Vaspoli, Loewe Kasprenski, Gerald A Zsido, Joseph H Gorman, Robert C Gorman, Joshua D Rabinowitz
No abstract text is available yet for this article.
September 6, 2022: Cell Metabolism
#18
JOURNAL ARTICLE
Emily R Edwards, Matthew M Goldsmith, Hannah N Tran, Nicole K Bulanchuk, Gabriella Epshteyn, Joseph Wrobleski, David G May, Shayne Snyder, Alice S Lee, Katharine F Schofield, Daniel Gorman, Ariana Dichiara, Joseph C Geraci
Each year, approximately 200,000 service members transition out of military service and return to civilian life. For many, the stresses of this military-to-civilian transition are vast and include instabilities in mental health, relationships, employment, education, and housing. Given their unique training, mental health professionals often find themselves on the front lines of efforts to support this population. However, to date, literature to guide work with this population has been scant and disorganized...
September 1, 2022: Psychological Services
#19
JOURNAL ARTICLE
Bruno V Rego, Amir H Khalighi, Joseph H Gorman, Robert C Gorman, Michael S Sacks
Left ventricular myocardial infarction (MI) has broad and debilitating effects on cardiac function. In many cases, MI leads to ischemic mitral regurgitation (IMR), a condition characterized by incompetency of the mitral valve (MV). IMR has many deleterious effects as well as a high mortality rate. While various clinical treatments for IMR exist, success of these procedures remains limited, in large part because IMR dramatically alters the geometry and function of the MV in ways that are currently not well understood...
August 27, 2022: Annals of Biomedical Engineering
#20
JOURNAL ARTICLE
Philip El-Duah, Augustina Angelina Sylverken, Michael Owusu, Yaw Ampem Amoako, Richmond Yeboah, Richmond Gorman, Emmanuella Nyarko-Afriyie, Julia Schneider, Terry C Jones, Joseph Bonney, Titus Adade, Eric Smart Yeboah, Tabea Binger, Victor Max Corman, Christian Drosten, Richard Odame Phillips
BACKGROUND: Encephalitis is a serious disease of the brain characterized by prodromal and specific neurological symptoms. HIV infections offer opportunistic viruses, such as Varicella-zoster virus (VZV), the chance to cause encephalitis in patients. There is a lack of information on the genetic diversity of VZV in Ghana and other parts of Africa which requires sequencing and characterization studies to address. The active evolution of HIV-1 in West Africa also requires continuous surveillance for the emergence of new genetic forms...
July 26, 2022: Virology Journal
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