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https://www.readbyqxmd.com/read/28100570/a-rare-cause-of-constrictive-pericarditis
#1
Shane Patrick Flood, Omar Ayah, Satoshi Furukawa, Robert B Norris
A 67-year-old man presented with 3 months of exertional dyspnoea and 1 week of oedema. Examination revealed elevated neck veins, pulsus paradoxus, muffled heart sounds, decreased breath sounds and pedal oedema. Transthoracic echocardiogram (TTE) demonstrated cardiac tamponade, and chest X-ray showed pleural effusion. Pericardiocentesis, thoracocentesis, laboratory investigations and CT did not elucidate an underlying aetiology. Three weeks later, he presented with recurrent cardiac tamponade and pleural effusion...
January 18, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28099004/nickel-mediated-decarbonylation-of-simple-unstrained-ketones-through-the-cleavage-of-carbon%C3%A2-carbon-bonds
#2
Toshifumi Morioka, Akihiro Nishizawa, Takayuki Furukawa, Mamoru Tobisu, Naoto Chatani
Despite advances in methods for the decarbonylation of aldehydes, the decarbonylation of ketones has met with limited success be-cause this process requires the activation of two inert carbon-carbon bonds. All of the decarbonylation reactions of simple unstained ketones reported to date require the addition of a stoichiometric rhodium complex. We report herein the nickel/N-heterocyclic car-bene-mediated decarbonylation of simple diary ketones. This reac-tion shows unique acceleration effects based on the presence of both electron-donating and electron-withdrawing groups...
January 18, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28098535/outbreak-of-legionnaire-s-disease-caused-by-legionella-pneumophila-serogroups-1-and-13
#3
Toshiro Kuroki, Junko Amemura-Maekawa, Hitomi Ohya, Ichiro Furukawa, Miyuki Suzuki, Tomoka Masaoka, Kastuhiro Aikawa, Kazumi Hibi, Masatomo Morita, Ken-Ichi Lee, Makoto Ohnishi, Fumiaki Kura
In Japan, hot springs and public baths are the major sources of legionellosis. In 2015, an outbreak of Legionnaires' disease occurred among 7 patients who had visited a spa house. Laboratory investigation indicated that L. pneumophila serogroup 1 and 13 strains caused the outbreak and that these strains were genetically related.
February 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28095852/the-st-george-s-respiratory-questionnaire-as-a-prognostic-factor-in-ipf
#4
Taiki Furukawa, Hiroyuki Taniguchi, Masahiko Ando, Yasuhiro Kondoh, Kensuke Kataoka, Osamu Nishiyama, Takeshi Johkoh, Junya Fukuoka, Koji Sakamoto, Yoshinori Hasegawa
BACKGROUND: It is unclear whether health related quality of life (HRQL) may have a predictive value for mortality in idiopathic pulmonary fibrosis (IPF). We investigated the relationship between HRQL assessed using the St. George's Respiratory Questionnaire (SGRQ) and survival time in patients with IPF, and tried to determine a clinical meaningful cut off value to predict poorer survival rates. METHODS: We retrospectively analyzed consecutive patients with IPF who underwent an initial evaluation from May 2007 to December 2012...
January 17, 2017: Respiratory Research
https://www.readbyqxmd.com/read/28094003/recombinant-thrombomodulin-suppresses-tumor-growth-of-pancreatic-cancer-by-blocking-thrombin-induced-par1-and-nf-%C3%AE%C2%BAb-activation
#5
Yoshihiro Shirai, Tadashi Uwagawa, Hiroaki Shiba, Yohta Shimada, Takashi Horiuchi, Nobuhiro Saito, Kenei Furukawa, Toya Ohashi, Katsuhiko Yanaga
BACKGROUND: Thrombomodulin, an anticoagulant that inhibits thrombin-induced growth factor promotion, also has an anti-inflammatory effect. Furthermore, thrombomodulin inhibits nuclear factor-kappa B activation, which plays a crucial role in cancer progression. We assessed the antitumor activity of recombinant thrombomodulin for pancreatic cancer. METHODS: A xenograft orthotopic model was established in mice by implantation of human pancreatic cancer cells. The animals were treated with intraperitoneal injection of recombinant thrombomodulin 5 times a week for 4 weeks...
January 13, 2017: Surgery
https://www.readbyqxmd.com/read/28092868/a-practical-evaluation-of-measurement-uncertainty-in-gamma-ray-efficiency-curve-determination-through-an-analytical-approach
#6
Katsuhiro Shirono, Yasuhiro Unno, Rio Furukawa, Chushiro Yonezawa
An example of uncertainty evaluation of an efficiency curve is reported. In the applied method, the efficiency curve is determined through the weighted least square method based on measured efficiencies employing a mixed-radionuclide standard source. The variance-covariance matrix of the efficiencies is determined by evaluating the uncertainties of the counting, the calibrated radioactivities, the correction factors for true coincidence summing, and the inadequacy of the fitting function. The proposed method can be a basis to develop a more general procedure...
December 15, 2016: Applied Radiation and Isotopes
https://www.readbyqxmd.com/read/28088806/effects-of-aloe-sterol-supplementation-on-skin-elasticity-hydration-and-collagen-score-a-12-week-double-blind-randomized-controlled-trial
#7
Miyuki Tanaka, Yuki Yamamoto, Eriko Misawa, Kazumi Nabeshima, Marie Saito, Koji Yamauchi, Fumiaki Abe, Fukumi Furukawa
BACKGROUND/AIMS: Our previous study confirmed that Aloe sterol stimulates collagen and hyaluronic acid production in human dermal fibroblasts. This study aims to investigate whether Aloe sterol intake affects skin conditions. METHODS: We performed a 12-week, randomized, double-blind, placebo-controlled study to evaluate the effects of oral Aloe sterol supplementation on skin elasticity, hydration, and the collagen score in 64 healthy women (age range 30-59 years; average 44...
January 14, 2017: Skin Pharmacology and Physiology
https://www.readbyqxmd.com/read/28087289/clinical-utility-and-functional-analysis-of-variants-in-atrial-fibrillation-associated-locus-4q25
#8
Yusuke Ebana, Kouichi Ozaki, Lian Liu, Hitoshi Hachiya, Kenzo Hirao, Mitsuaki Isobe, Michiaki Kubo, Toshihiro Tanaka, Tetsushi Furukawa
BACKGROUND: Chromosome 4q25 has been repeatedly identified as atrial fibrillation (AF)-sensitive locus in multiple genome-wide association studies (GWAS) and is considered to hold some clues to AF pathogenesis. We aimed to investigate the clinical utilities in Japanese and to unveil the function of the 4q25 locus in affecting transcription of adjacent genes. METHODS: We conducted AF GWAS in Japanese population (1382 AF cases and 1478 controls) and the replication panel (1666 AF cases and 1229 controls) with detailed clinical information which showed the acceleration of AF onset...
January 10, 2017: Journal of Cardiology
https://www.readbyqxmd.com/read/28081259/frequency-of-propionibacterium-acnes-infection-in-prostate-glands-with-negative-biopsy-results-is-an-independent-risk-factor-for-prostate-cancer-in-patients-with-increased-serum-psa-titers
#9
Tomoya Kakegawa, Yuan Bae, Takashi Ito, Keisuke Uchida, Masaki Sekine, Yutaka Nakajima, Asuka Furukawa, Yoshimi Suzuki, Jiro Kumagai, Takumi Akashi, Yoshinobu Eishi
BACKGROUND: Propionibacterium acnes has recently been implicated as a cause of chronic prostatitis and this commensal bacterium may be linked to prostate carcinogenesis. The occurrence of intracellular P. acnes infection in prostate glands and the higher frequency of P. acnes-positive glands in radical prostatectomy specimens from patients with prostate cancer (PCa) than in those from patients without PCa led us to examine whether the P. acnes-positive gland frequency can be used to assess the risk for PCa in patients whose first prostate biopsy, performed due to an increased prostate-specific antigen (PSA) titer, was negative...
2017: PloS One
https://www.readbyqxmd.com/read/28079613/centripetal-movement-of-the-capillaries-in-the-central-macular-region-after-internal-limiting-membrane-peeling
#10
Kazuyuki Kumagai, Masanori Hangai, Mariko Furukawa, Tetsuyuki Suetsugu, Nobuchika Ogino
PURPOSE: To report a case that showed centripetal movements of the capillaries in the central macular region after vitrectomy with internal limiting membrane peeling. METHODS: A 57-year-old pseudophakic woman underwent successful vitrectomy with internal limiting membrane peeling and air tamponade for a vitreomacular traction. Optical coherence tomography angiographic images of the 3 mm × 3 mm inner retinal vascular plexus were examined preoperatively and at 3 months postoperatively...
January 11, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28074366/improved-slant-drilling-well-for-in-situ-remediation-of-groundwater-and-soil-at-contaminated-sites
#11
Yasuhide Furukawa, Kazuhiro Mukai, Keisuke Ohmura, Takeshi Kobayashi
Soil contamination has become a crucial issue in urban redevelopment. Japan has many contaminated sites on which manufacturing has been conducted over several decades. Site holders are now under pressure to manage chemical contamination; however, the use of heavy machinery is difficult in remedial operations on restricted sites, especially where there are still working factories. The slant well is a potentially useful technique in such settings, but its use is technically challenging because of the need for high drilling accuracy and the difficulty in sealing the slanted bores...
January 10, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28073848/cardiac-and-noncardiac-causes-of-long-term-mortality-in-st-segment-elevation-acute-myocardial-infarction-patients-who-underwent-primary-percutaneous-coronary-intervention
#12
Yugo Yamashita, Hiroki Shiomi, Takeshi Morimoto, Hidenori Yaku, Yutaka Furukawa, Yoshihisa Nakagawa, Kenji Ando, Kazushige Kadota, Mitsuru Abe, Kazuya Nagao, Satoshi Shizuta, Koh Ono, Takeshi Kimura
BACKGROUND: In patients with ST-segment-elevation acute myocardial infarction (STEMI) who underwent primary percutaneous coronary intervention, long-term risks for cardiac and noncardiac death beyond acute phase of STEMI have not been thoroughly evaluated yet. METHODS AND RESULTS: We identified 3942 STEMI patients who had primary percutaneous coronary intervention within 24 hours after onset between January 2005 and December 2007 in the CREDO-Kyoto AMI registry (Coronary Revascularization Demonstrating Outcome study in Kyoto Acute Myocardial Infarction) and evaluated their short-term (within 6-month) and long-term (beyond 6-month) incidences and causes of deaths...
January 2017: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/28072656/isosorbide-induced-decompression-effect-on-the-scala-media-participation-of-plasma-osmolality-and-plasma-arginine-vasopressin
#13
Taizo Takeda, Setsuko Takeda, Natsumi Uehara, Shungaku Yanagisawa, Tatsuya Furukawa, Ken-Ichi Nibu, Akinobu Kakigi
OBJECTIVE: The correlation between the isosorbide-induced decompression effect on the endolymphatic space and plasma osmolality (p-OSM) or plasma arginine vasopressin (p-AVP) was investigated on comparing two different dosages of isosorbide (2.8 and 1.4 g/kg) to elucidate why the decompression effect is delayed with a large dose of isosorbide. MATERIALS AND METHODS: Two experiments were performed using 80 guinea pigs. Experiment 1 was designed to morphologically investigate the sequential influence of the oral intake of 1...
January 9, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28070328/safety-and-feasibility-of-single-incision-laparoscopic-cholecystectomy-in-obese-patients
#14
Masaki Wakasugi, Masahiro Tanemura, Mitsuyoshi Tei, Kenta Furukawa, Yozo Suzuki, Toru Masuzawa, Kentaro Kishi, Hiroki Akamatsu
BACKGROUND: Current literature frequently indicates that experienced laparoscopic surgeons can safely perform single-incision laparoscopic cholecystectomy, but there have been few reports evaluating the feasibility and safety of performing single-incision laparoscopic cholecystectomy for obese patients. Therefore, a large single-center database was retrospectively reviewed to evaluate the feasibility and safety of single-incision laparoscopic cholecystectomy for obese patients by comparing the outcomes of normal-weight and obese patients undergoing single-incision laparoscopic cholecystectomy...
January 2017: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/28070077/voltage-induced-infrared-absorption-from-a-spin-cast-thin-film-of-ferroelectric-poly-vinylidene-fluoride-co-trifluoroethylene-p-vdf-trfe
#15
Kenji Takashima, Yukio Furukawa
Voltage-induced infrared spectra of annealed spin-cast thin films of ferroelectric poly(vinylidene fluoride-co-trifluoroethylene) (P(VDF-TrFE)) (molar ratio, 3:1) were measured in a stepwise cyclic external electric field. Most of the observed infrared bands originated from the β ferroelectric crystalline phase. The voltage-induced spectral changes were decomposed into zeroth- (original), first-, and second-derivative spectra, and were attributed to the rotational motions of the polymer chains and the vibrational Stark effect...
2017: Analytical Sciences: the International Journal of the Japan Society for Analytical Chemistry
https://www.readbyqxmd.com/read/28069106/portal-vein-thrombosis-after-reconstruction-in-270-consecutive-patients-with-portal-vein-resections-in-hepatopancreatobiliary-hpb-surgery
#16
Masaru Miyazaki, Hiroaki Shimizu, Masayuki Ohtuka, Atsushi Kato, Hiroyuki Yoshitomi, Katsunori Furukawa, Tsukasa Takayashiki, Satoshi Kuboki, Shigetsugu Takano, Daisuke Suzuki, Taku Higashihara
BACKGROUNDS: This study was aimed to evaluate the occurrence of portal vein thrombosis after portal vein reconstruction. METHODS: The portal veins were repaired with venorrhaphy, end-to-end, patch graft, and segmental graft in consecutive 270 patients undergoing hepato-pancreto-biliary (HPB) surgery. RESULTS: Portal vein thrombosis was encountered in 20 of 163 of end-to-end, 2 of 56 of venorrhaphy, and 2 of 5 of patch graft groups, as compared with 0 of 46 of segmental graft group (p < 0...
December 24, 2016: American Journal of Surgery
https://www.readbyqxmd.com/read/28068304/benefits-of-high-dose-steroid%C3%A2-%C3%A2-hespander%C3%A2-%C3%A2-mannitol-administration-in-the-treatment-of-bell-s-palsy
#17
Takatoshi Furukawa, Yasuhiro Abe, Tsukasa Ito, Toshinori Kubota, Seiji Kakehata
OBJECTIVE: Large-scale investigations have not been recently conducted on the efficacy of high-dose steroid administration of prednisolone (PSL) for Bell's palsy. We compared treatment results between normal-dose steroid (PSL 60 mg/d) and high-dose steroid (PSL 200 mg/d) + Hespander + Mannitol administration. We also investigated the recovery rate for antiviral agents. STUDY DESIGN: Retrospective case review. SETTING: Tertiary referral center...
February 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28067302/effects-of-alcohol-abstinence-on-glucose-metabolism-in-japanese-men-with-elevated-fasting-glucose-a-pilot-study
#18
Takashi Funayama, Yoshifumi Tamura, Kageumi Takeno, Minako Kawaguchi, Saori Kakehi, Takahiro Watanabe, Yasuhiko Furukawa, Hideyoshi Kaga, Risako Yamamoto, Akio Kanazawa, Yoshio Fujitani, Ryuzo Kawamori, Hirotaka Watada
It has been demonstrated that moderate alcohol consumption provides protection against the development of type 2 diabetes. However, several other reports suggested that moderate alcohol intake may increase the risk of type 2 diabetes in non-obese Japanese. The aim of present study was to investigate the effect of 1-week alcohol abstinence on hepatic insulin sensitivity and fasting plasma glucose (FPG) in non-obese Japanese men. We recruited 8 non-obese Japanese men with mildly elevated FPG and drinking habits alcohol (mean frequency; 5...
January 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28064397/review-and-proposal-of-regional-surgical-management-for-melanoma-revisiting-of-integumentectomy-and-incontinuity-dissection-in-treatment-of-skin-melanoma
#19
Toshihiko Hayashi, Hiroshi Furukawa, Takashi Kitamura, Ryuji Shichinohe, Naoki Murao, Akihiko Oyama, Emi Funayama, Taku Maeda, Yuhei Yamamoto
BACKGROUND: Past studies showed that integumentectomy and incontinuity could be effective procedures in the surgical management of melanoma patients. The present study reports on the historical background of these procedures. In addition, we analyze the ICG assisted integumentectomy and incontinuity techniques and algorithms that we had created when performing this procedure. METHOD: In accordance with our algorithm, we performed ICG assisted integumentectomy/incontinuity procedures on 17 patients with stage III melanomas between 2008 and 2016...
January 7, 2017: International Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28064364/significance-of-right-atrial-tension-for-the-development-of-complications-in-patients-after-atriopulmonary-connection-fontan-procedure-potential-indicator-for-fontan-conversion
#20
Gaku Izumi, Hideaki Senzaki, Atsuhito Takeda, Hirokuni Yamazawa, Kohta Takei, Takuo Furukawa, Kei Inai, Tokuko Shinohara, Toshio Nakanishi
Elevated right atrial (RA) pressure and progressive RA dilation are thought to play pivotal roles in the development of late complications after atriopulmonary connection (APC) Fontan surgery. However, no clear cut-off value for RA pressure or RA volume has been determined for stratifying the risk of developing Fontan complications. We hypothesized that RA tension, which incorporates information about both RA pressure and volume, might help predict the risk of developing complications. We retrospectively studied 51 consecutive APC Fontan patients (median postoperative period 14 years)...
January 7, 2017: Heart and Vessels
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