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Pavan Atluri

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https://www.readbyqxmd.com/read/28459740/engineering-the-future-one-cell-at-a-time-advancements-in-cell-based-techniques-from-novel-three-dimensional-cell-culture-to-a-bionic-kidney
#1
Jennifer J Chung, Maria F Arisi, Samir Zaman, Pavan Atluri
No abstract text is available yet for this article.
May 2017: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/28457697/extended-distance-cardiac-allograft-can-successfully-be-utilized-without-impacting-long-term-survival
#2
Ann C Gaffey, Carol W Chen, Jennifer J Chung, Jason Han, Anjali Owens, Michael A Acker, Pavan Atluri
BACKGROUND: Despite the severe shortage of donor cardiac allografts, the general belief in worse outcomes with donors from prolonged distances has resulted in many centers greatly limiting the acceptable geographic distance of acceptable donors. However, with improvements in allograft preservation, it is likely that distance may be extended without compromising graft integrity. We hypothesized that recipients of appropriately selected allografts from greater distances would have equivalent long-term survival compared with recipients from closer geographic regions...
April 15, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/28431737/examining-the-dark-recesses-of-the-heart-technology-drives-innovation
#3
EDITORIAL
Malini Daniel, Pavan Atluri
No abstract text is available yet for this article.
April 3, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28341625/non-cardiac-surgery-in-patients-with-continuous-flow-left-ventricular-assist-devices-a-single-institutional-experience
#4
Carol W Chen, Kristoffel R Dumon, Oren Shaked, Michael A Acker, Pavan Atluri, Daniel T Dempsey
With improvements in life expectancy for patients with continuous-flow left ventricular assist devices (LVADs), non-cardiac surgeons will increasingly encounter surgical problems in this population. 209 patients underwent LVAD placement between 10/1/2007 and 6/1/2015 at a single institution. Survival was compared between patients who had non-cardiac surgery (NCS) during the initial LVAD implantation hospitalization (n=36) and those who had NCS only in subsequent hospitalizations (n=33). Postoperative complication rates were examined...
March 24, 2017: Journal of Investigative Medicine: the Official Publication of the American Federation for Clinical Research
https://www.readbyqxmd.com/read/28325654/the-year-in-cardiothoracic-critical-care-selected-highlights-from-2016
#5
REVIEW
Jacob T Gutsche, Kamrouz Ghadimi, John G T Augoustides, Adam Evans, Hanjo Ko, Menachem Weiner, Jesse Raiten, Meghan Lane-Fall, Emily Gordon, Pavan Atluri, Rita Milewski, Jiri Horak, Prakash Patel, Harish Ramakrishna
No abstract text is available yet for this article.
April 2017: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/28314504/low-ejection-fraction-in-donor-hearts-is-not-directly-associated-with-increased-recipient-mortality
#6
Carol W Chen, Michael H Sprys, Ann C Gaffey, Jennifer J Chung, Kenneth B Margulies, Michael A Acker, Pavan Atluri
BACKGROUND: Reduced left ventricular ejection fraction (EF) in the donor heart is often a contraindication for transplant. However, small studies have validated the use of hearts with evidence of myocardial dysfunction to boost the number of organs available for transplant. We hypothesize that donor hearts with reduced EF undergo myocardial recovery after transplant and result in equivalent recipient survival compared with grafts with normal function. METHODS: We examined post-operative outcomes of heart recipients in the database of the United Network for Organ Sharing...
February 4, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/28258242/successful-cardiac-transplantation-outcomes-in-patients-with-adult-congenital-heart-disease
#7
Jonathan N Menachem, Jessica R Golbus, Maria Molina, Jeremy A Mazurek, Nicole Hornsby, Pavan Atluri, Stephanie Fuller, Edo Y Birati, Yuli Y Kim, Lee R Goldberg, Joyce W Wald
OBJECTIVES: The purpose of our study is (1) to characterise patients with congenital heart disease undergoing heart transplantation by adult cardiac surgeons in a large academic medical centre and (2) to describe successful outcomes associated with our multidisciplinary approach to the evaluation and treatment of adults with congenital heart disease (ACHD) undergoing orthotopic heart transplantation (OHT). BACKGROUND: Heart failure is the leading cause of death in patients with ACHD leading to increasing referrals for OHT...
March 3, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28242019/gone-fishing-looking-to-catch-some-answers-for-differing-mortality-in-the-corevalve-high-risk-trial
#8
EDITORIAL
Arman Kilic, Pavan Atluri
No abstract text is available yet for this article.
February 3, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28176387/bridge-with-a-left-ventricular-assist-device-to-a-simultaneous-heart-and-kidney-transplant-review-of-the-united-network-for-organ-sharing-database
#9
Ann C Gaffey, Carol W Chen, Jennifer Chung, Edward Wilson Grandin, Paige M Porrett, Michael A Acker, Pavan Atluri
BACKGROUND: Left ventricular assist device (LVAD) implantation as a bridge to cardiac transplantation (BTT) is an effective treatment for end-stage heart failure patients. Currently, there is an increasing number of patients with a LVAD who need a heart and kidney transplant (HKT). Little is known of the prognostic outcomes in these patients. This study was undertaken to determine whether an equivalent outcome would be present in HKTs as compared to a non-LVAD primary HKT cohort. METHODS: We reviewed the United Network for Organ Sharing database from 2004 to 2013...
February 8, 2017: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/28003575/higher-body-mass-index-increases-risk-of-heartmate-ii-pump-thrombosis-but-does-not-adversely-affect-long-term-survival
#10
Jason J Han, Renganaden Sooppan, Adam P Johnson, Carol W Chen, Ann C Gaffey, Emily C Phillips, Jessica Howard, J Eduardo Rame, Michael A Acker, Pavan Atluri
BACKGROUND: Obesity has been correlated with various adverse events in patients who receive left ventricular assist devices (LVAD). In this study, we sought to further characterize the role of obesity in this patient population.Methods and Results:We performed a retrospective analysis of 164 patients implanted with a HeartMate II from August 2008 to December 2014. Patients were categorized into 2 BMI groups based on WHO guidelines: BMI 18.5-30 kg/m(2)(n=99) and BMI >30 kg/m(2)(n=65)...
January 25, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/27997133/injectable-guest-host-assembled-polyethylenimine-hydrogel-for-sirna-delivery
#11
Leo L Wang, Janna N Sloand, Ann C Gaffey, Chantel M Venkataraman, Zhichun Wang, Alen Trubelja, Daniel A Hammer, Pavan Atluri, Jason A Burdick
While siRNA has tremendous potential for therapeutic applications, advancement is limited by poor delivery systems. Systemically, siRNAs are rapidly degraded, may have off-target silencing, and necessitate high working concentrations. To overcome this, we developed an injectable, guest-host assembled hydrogel between polyethylenimine (PEI) and polyethylene glycol (PEG) for local siRNA delivery. Guest-host modified polymers assembled with siRNAs to form polyplexes that had improved transfection and viability compared to PEI...
December 20, 2016: Biomacromolecules
https://www.readbyqxmd.com/read/27756463/off-pump-ventricular-assist-device-implantation-easy-as-1-2-3
#12
EDITORIAL
Arman Kilic, Pavan Atluri
No abstract text is available yet for this article.
January 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27726874/transdifferentiation-a-new-frontier-in-cardiovascular-cell-therapy
#13
EDITORIAL
Michael Ibrahim, Pavan Atluri
No abstract text is available yet for this article.
January 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27717422/left-ventricular-assist-device-design-reduces-von-willebrand-factor-degradation-a-comparative-study-between-the-heartmate-ii-and-the-evaheart-left-ventricular-assist-system
#14
Carlo R Bartoli, Jooeun Kang, David Zhang, Jessica Howard, Michael Acker, Pavan Atluri, Tadashi Motomura
BACKGROUND: Supraphysiologic shear stress from continuous-flow left ventricular assist devices (LVADs) accelerates von Willebrand factor (vWF) degradation and predisposes patients to nonsurgical bleeding. It is unknown whether unique design characteristics of LVADs differentially affect vWF degradation. We tested the hypothesis that the centrifugal-flow EVAHEART (Evaheart, Houston, TX) left ventricular assist system (LVAS), which was designed to minimize shear stress (low operational revolutions per minute [rpm], larger flow gaps, low shear stress, flat H-Q curve), reduced vWF degradation versus the axial-flow HeartMate II (Thoratec, Pleasanton, CA) LVAD...
October 4, 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27544289/valve-selection-in-end-stage-renal-disease-should-it-always-be-biological
#15
COMPARATIVE STUDY
Matthew L Williams, Joseph E Bavaria, Michael A Acker, Nimesh D Desai, Prashanth Vallabhajosyula, W Clark Hargrove, Pavan Atluri, Wilson Y Szeto
BACKGROUND: When valve replacement is required in patients with end-stage renal disease (ESRD), it is not clear if mechanical or bioprosthetic valve selection is better. We compared outcomes between ESRD patients who underwent either mechanical or biologic valve replacements at our institution. METHODS: All patients with ESRD who underwent either mitral or aortic valve replacement from 2002 to 2014 at our institution were reviewed (n = 215; mechanical = 64, biological = 151)...
November 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27498902/left-ventricular-assist-devices-and-small-body-surface-area%C3%A3-a-clinical-concern
#16
EDITORIAL
Michael Ibrahim, Arman Kilic, Pavan Atluri
No abstract text is available yet for this article.
August 25, 2016: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/27485679/stapled-aortic-graft-to-graft-anastomoses-is-automation-optimization
#17
EDITORIAL
Arman Kilic, Pavan Atluri
No abstract text is available yet for this article.
October 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27476028/nonfunctional-pacemaker-leads-to-remove-or-not-to-remove-that-is-the-multifactorial-question
#18
EDITORIAL
Carol W Chen, Pavan Atluri
No abstract text is available yet for this article.
October 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27469015/right-ventricular-response-to-pulsatile-load-is-associated-with-early-right-heart-failure-and-mortality-after-left-ventricular-assist-device
#19
E Wilson Grandin, Payman Zamani, Jeremy A Mazurek, Gregory S Troutman, Edo Y Birati, Esther Vorovich, Julio A Chirinos, Ryan J Tedford, Kenneth B Margulies, Pavan Atluri, J Eduardo Rame
BACKGROUND: Right ventricular (RV) adaptation to afterload is crucial for patients undergoing continuous-flow left ventricular assist device (cf-LVAD) implantation. We hypothesized that stratifying patients by RV pulsatile load, using pulmonary arterial compliance (PAC), and RV response to load, using the ratio of central venous to pulmonary capillary wedge pressure (CVP:PCWP), would identify patients at high risk for early right heart failure (RHF) and 6-month mortality after cf-LVAD...
January 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/27207130/lower-extremity-complications-with-femoral-extracorporeal-life-support
#20
Prashanth Vallabhajosyula, Matthew Kramer, Sofiane Lazar, Fenton McCarthy, Eduardo Rame, Joyce Wald, Wilson Szeto, Matthew Williams, Pavan Atluri, Nimesh Desai, Michael Acker
OBJECTIVE: Patients undergoing emergency peripheral arteriovenous extracorporeal life support were evaluated for lower-extremity complications on the basis of the ipsilateral limb perfusion strategy. METHODS: In a retrospective review of patients receiving extracorporeal life support (2008-2013), 105 of 250 underwent femoral extracorporeal life support. For ipsilateral lower-extremity perfusion, patients underwent no superficial femoral artery cannulation (n = 35), percutaneous superficial femoral artery cannulation (n = 23), or open superficial femoral artery cannulation (n = 47)...
June 2016: Journal of Thoracic and Cardiovascular Surgery
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