keyword
https://read.qxmd.com/read/38544636/integrative-approach-of-conventional-physiotherapy-mulligan-s-mobilisation-with-movement-and-plyometric-training-in-a-young-volleyball-athlete-after-anterior-cruciate-ligament-acl-reconstruction-a-case-report
#1
Pratik R Jaiswal, Swapnil U Ramteke, Subrat Samal
The requirements of volleyball include specialized, strategic, and acrobatic skills. In volleyball, it is thus essential to build maximal power and strength properly. Strengthening has been recommended as an effective means to avoid injuries and build muscle strength. It also enhances one's health in relation to performance in the game. Anterior cruciate ligament (ACL) tears are a common knee injury affecting athletes of all levels. A big problem with injury healing and getting back to sports is that there isn't a tried-and-true protocol or set of steps an athlete should follow following an ACL injury...
February 2024: Curēus
https://read.qxmd.com/read/38540898/adulteration-of-brain-health-cognitive-mood-and-sleep-enhancement-food-supplements-by-the-addition-of-pharmaceutical-drugs-a-comprehensive-review-of-analytical-approaches-and-trends
#2
REVIEW
Rafael Paiva, Manuela Correia, Cristina Delerue-Matos, Joana S Amaral
In recent years, the consumption of dietary supplements has grown worldwide, particularly in developed regions. However, this growing market has also become a prime target for adulteration practices, with some manufacturers illegally adding pharmaceuticals into plant-based food supplements (PFS) to enhance their effects. While extensive research has focused on detecting adulterant drugs in PFS tailored for improving sexual performance, weight loss, and muscle building, less attention has been given to supplements intended for mood enhancement, sleep aid, and cognitive function (nootropics)...
March 16, 2024: Foods (Basel, Switzerland)
https://read.qxmd.com/read/38536803/electromyographic-activity-of-pelvic-floor-muscles-in-different-positions-during-the-use-an-innovative-vaginal-educator-cross-sectional-study
#3
JOURNAL ARTICLE
Natália de Souza Duarte, Yury Souza De Azevedo, Emilly Cássia Soares Furtado, Lorena Jarid Freire De Araújo, Rayanne Mesquita Bendelack, Cibele Nazaré Câmara Rodrigues, Nazete Dos Santos Araujo, Pablo Fabiano Moura das Neves, Ana Clara Nunes Soares, Rayana Carvalho Barros, Tainah Lacerda Santos, Erica Feio Carneiro Nunes, Elizabeth Alves Gonçalves Ferreira, Bianca Callegari, João Simão de Melo-Neto
The pelvic floor requires an integrated anatomical structure owing to its multiple functions. Therefore, it is necessary to study methods for improving muscle recruitment during training. This study aimed to analyze the effect of using an innovative vaginal trainer on the bioelectrical activity of the pelvic floor muscles. Pelvic positioning and interference factors, such as age, childbirth, sexual activity, urinary incontinence, and menopause, were also analyzed. A cross-sectional study assessed 30 women using an evaluation form, International Consultation on Incontinence Questionnaire-Short Form, and surface electromyography...
2024: PloS One
https://read.qxmd.com/read/38533721/new-developments-in-cosmetic-applications-of-electromagnetic-fields-client-and-occupational-hazard-assessment
#4
REVIEW
Rianne Stam
Energy-based devices are used to improve features of appearance for aesthetic reasons while avoiding more invasive methods. Examples of treatment targets are the reduction of wrinkles, sagging, unwanted skin lesions, body hair and excess fatty tissue, and the enhancement of muscle tissue. One treatment modality is the use of electromagnetic fields (EMF, 0‒300 GHz). The present work aims to give an up-to-date survey of cosmetic applications of EMF for professional use with an assessment of client and worker exposure and possible adverse effects...
March 27, 2024: Bioelectromagnetics
https://read.qxmd.com/read/38524234/circulating-mir-129-3p-in-combination-with-clinical-factors-predicts-vascular-calcification-in-hemodialysis-patients
#5
JOURNAL ARTICLE
Jingjing Jin, Meijuan Cheng, Xueying Wu, Haixia Zhang, Dongxue Zhang, Xiangnan Liang, Yuetong Qian, Liping Guo, Shenglei Zhang, Yaling Bai, Jinsheng Xu
BACKGROUND: Vascular calcification (VC) commonly occurs and seriously increases the risk of cardiovascular events and mortality in patients with hemodialysis. For optimizing individual management, we will develop a diagnostic multivariable prediction model for evaluating the probability of VC. METHODS: The study was conducted in four steps. First, identification of miRNAs regulating osteogenic differentiation of vascular smooth muscle cells (VSMCs) in calcified condition...
March 2024: Clinical Kidney Journal
https://read.qxmd.com/read/38517831/influence-of-brick-laying-height-on-biomechanical-load-in-masons-cross-sectional-field-study-with-technical-measurements
#6
JOURNAL ARTICLE
Mikkel Brandt, Rúni Bláfoss, Markus Due Jakobsen, Afshin Samani, Jeppe Z N Ajslev, Pascal Madeleine, Lars L Andersen
BACKGROUND: Work-related musculoskeletal disorders (WMSDs) located in the low back and neck/shoulder regions are major concerns for both workers, workplaces, and society. Masons are prone to WMSD, because their work is characterized by repetitive work and high physical workload. However, the knowledge on the physical workload during bricklaying is primarily based on subjective measurements. OBJECTIVE: This cross-sectional field study with technical measurements aimed to quantify physical workload in terms of muscular activity and degree of forward bending during bricklaying at different working heights among masons, i...
March 19, 2024: Work: a Journal of Prevention, Assessment, and Rehabilitation
https://read.qxmd.com/read/38517769/effects-of-short-foot-training-on-foot-posture-in-patients-with-flatfeet-a-systematic-review-and-meta-analysis
#7
REVIEW
Jinling Cheng, Dongmiao Han, Jiayang Qu, Zicai Liu, Ying Huang
BACKGROUND: With lifestyle changes, the prevalence of flatfoot is increasing year by year, with a prevalence of 29%. Flatfoot will lead to an inevitable injury and reduce the quality of life. Short foot exercises can enhance the strength of the intrinsic muscles of the foot and improve the symptoms of flatfoot. However, there is controversy regarding its specific efficacy. OBJECTIVE: This meta-analysis quantitatively evaluates the effect of short foot training on patients with flatfeet and provides evidence to inform the clinical approach to short foot training in patients with flat feet...
February 27, 2024: Journal of Back and Musculoskeletal Rehabilitation
https://read.qxmd.com/read/38514598/revealing-a-novel-methylated-integrin-alpha-8-related-to-extracellular-matrix-and-anoikis-resistance-using-proteomic-analysis-in-the-immune-microenvironment-of-lung-adenocarcinoma
#8
JOURNAL ARTICLE
Tingting Liu, Wen Ji, Xue Cheng, Lin Lv, Xiaohui Yu, Na Wang, Mengcong Li, Tinghua Hu, Zhihong Shi
Genomic epigenetics of extracellular matrix (ECM) play an important role in lung adenocarcinoma (LUAD). Our study identified a signature of potential prognostic genes associated with ECM and constructed immune risk-related prognosis model in LUAD. We downloaded mRNAs transcriptome data, miRNAs expression data, and clinical patient information for LUAD based on The Cancer Genome Atlas. "Limma, clusterProfiler, ggplot2" R packages and GSEA were used to analyze meaningful genes and explore potential biological function...
March 21, 2024: Molecular Biotechnology
https://read.qxmd.com/read/38506185/spatiotemporal-modulation-of-a-common-set-of-muscle-synergies-during-unpredictable-and-predictable-gait-perturbations-in-older-adults
#9
JOURNAL ARTICLE
Leon Brüll, Alessandro Santuz, Falk Mersmann, Sebastian Bohm, Michael Schwenk, Adamantios Arampatzis
Muscle synergies as functional low-dimensional building blocks of the neuromotor system regulate the activation patterns of muscle groups in a modular structure during locomotion. The purpose of the current study was to explore how older adults organize locomotor muscle synergies to counteract unpredictable and predictable gait perturbations during the perturbed and the recovery steps. Sixty-three healthy older adults (71.2 ± 5.2 years) participated in the study. Mediolateral and anteroposterior unpredictable and predictable perturbations during walking were introduced using a treadmill...
March 20, 2024: Journal of Experimental Biology
https://read.qxmd.com/read/38505523/a-protocol-for-the-prospective-study-of-urinary-cadmium-with-risk-of-fracture-bone-loss-and-muscle-loss
#10
JOURNAL ARTICLE
Christopher de la Bastide, Lissa Soares, Li-Yung Lui, James Harrington, Peggy Cawthon, Eric Orwoll, Deborah Kado, Jaymie Meliker
Cadmium (Cd) is a heavy metal and natural element found in soil and crops with increasing concentrations linked to phosphate fertilizers and sewage sludge applied to crop lands. A large fraction of older US men and woman have documented Cd exposure. Cd exposure has proven health concerns such as risk of lung cancer from inhalation and impaired renal function; however, growing evidence suggests it also influences bone and muscle health. Given that low levels of Cd could affect bone and muscle, we have designed prospective studies using the two largest and most detailed US studies of bone health in older men and women: the Osteoporotic Fractures in Men Study and the Study of Osteoporotic Fractures...
February 2024: JBMR Plus
https://read.qxmd.com/read/38495957/building-on-muscles-how-built-environment-design-impacts-modern-sports-science
#11
JOURNAL ARTICLE
Mohammad Javad Koohsari, Andrew T Kaczynski, Motohiko Miyachi, Koichiro Oka
Sports science focuses on enhancing athletes' performance, requiring a multifaceted approach. It is evolving from a purely muscle-centred approach to an interdisciplinary one. This paper investigates built environment design science, a dimension less explored in relation to enhancing athlete performance in sports science. The discussion is divided into three categories: athlete-centric training built environment design, enhanced fan and community engagement, and improved integrative accessibility. The study also identifies future research directions, including evidence of the relative impact of the built environment, financial aspects, and performance evaluation methods...
2024: BMJ Open Sport & Exercise Medicine
https://read.qxmd.com/read/38487400/preclinical-models-of-orthopaedic-trauma-orthopaedic-research-society-ors-and-orthopaedic-trauma-association-ota-symposium-2022
#12
JOURNAL ARTICLE
Patrick M Wise, Augustine M Saiz, Justin Haller, Joseph C Wenke, Thomas Schaer, Prism Schneider, Saam Morshed, Chelsea S Bahney
Orthopaedic trauma remains a leading cause of patient morbidity, mortality, and global health care burden. Although significant advances have been made in the diagnosis, treatment, and rehabilitation of these injuries, complications such as malunion, nonunion, infection, disuse muscle atrophy and osteopenia, and incomplete return to baseline function still occur. The significant inherent clinical variability in fracture care such as differing patient demographics, injury patterns, and treatment protocols make standardized and replicable study, especially of cellular and molecular based mechanisms, nearly impossible...
March 2024: OTA international: the open access journal of orthopaedic trauma
https://read.qxmd.com/read/38477382/functional-specialisation-and-coordination-of-myonuclei
#13
JOURNAL ARTICLE
Amaury Korb, Shahragim Tajbakhsh, Glenda E Comai
Myofibres serve as the functional unit for locomotion, with the sarcomere as fundamental subunit. Running the entire length of this structure are hundreds of myonuclei, located at the periphery of the myofibre, juxtaposed to the plasma membrane. Myonuclear specialisation and clustering at the centre and ends of the fibre are known to be essential for muscle contraction, yet the molecular basis of this regionalisation has remained unclear. While the 'myonuclear domain hypothesis' helped explain how myonuclei can independently govern large cytoplasmic territories, novel technologies have provided granularity on the diverse transcriptional programs running simultaneously within the syncytia and added a new perspective on how myonuclei communicate...
March 13, 2024: Biological Reviews of the Cambridge Philosophical Society
https://read.qxmd.com/read/38469980/examining-associations-between-disordered-eating-and-harmful-substance-use-in-a-nationally-representative-sample-of-us-veterans
#14
JOURNAL ARTICLE
Yiyang Chen, Kara A Christensen Pacella, Kelsie T Forbush, Marianna L Thomeczek, Sonakshi Negi, Alesha E Doan, Alicia M Wendler, R William Morgan, Samiya I Rasheed, Sarah Johnson-Munguia, Anjali R Sharma
OBJECTIVE: The association between eating disorders (EDs) and harmful substance use (substance use that causes psychosocial impairment) is well recognized in the literature, and military veterans may be at heightened risk for both issues due to deployment-related stressors. However, little is known about which ED-related symptoms are associated with harmful substance use in veterans, and whether gender plays a differential role in this relationship. Our aims were to: (1) examine gender differences in ED-related symptoms; and (2) examine whether ED-related symptoms differentially predict harmful substance use in US veteran men and women who had recently separated from service...
March 12, 2024: International Journal of Eating Disorders
https://read.qxmd.com/read/38465995/pilot-study-of-a-digital-behavioral-therapy-for-overactive-bladder-in-women
#15
JOURNAL ARTICLE
Celine Sooknarine, Sylvia Farrell, Susmita Sarma, Fadi Salameh, Naomi Burke, Brendan Staunton, Emma Carr, K Sexton, Gerry Agnew, Andrew Downey, Francis D'Arcy, Geoffrey W Cundiff
IMPORTANCE: The burden and high prevalence of overactive bladder (OAB) underline the urgent need for effective treatment. This study provides an initial look at an alternative approach to behavioral therapy for overactive bladder (OAB) that is delivered as an app on a smartphone. OBJECTIVE: This study aimed to investigate feasibility, acceptability, and preliminary efficacy of a digital therapeutic for OAB. STUDY DESIGN: This was a multicentered prospective pilot study...
March 7, 2024: Urogynecology (Phila)
https://read.qxmd.com/read/38446501/the-non-muscle-actinopathy-associated-mutation-e334q-in-cytoskeletal-%C3%AE-actin-perturbs-interaction-of-actin-filaments-with-myosin-and-adf-cofilin-family-proteins
#16
JOURNAL ARTICLE
Johannes N Greve, Anja Marquardt, Robin Heiringhoff, Theresia Reindl, Claudia Thiel, Nataliya Di Donato, Manuel H Taft, Dietmar J Manstein
Various heterozygous cytoskeletal γ-actin mutations have been shown to cause Baraitser-Winter cerebrofrontofacial syndrome, non-syndromic hearing loss, or isolated eye coloboma. Here, we report the biochemical characterization of human cytoskeletal γ-actin carrying mutation E334Q, a mutation that leads to a hitherto unspecified non-muscle actinopathy. Following expression, purification, and removal of linker and thymosin β4 tag sequences, the p.E334Q monomers show normal integration into linear and branched actin filaments...
March 6, 2024: ELife
https://read.qxmd.com/read/38442667/engines-of-change-nonmuscle-myosin-ii-in-mechanobiology
#17
REVIEW
Marina Garrido-Casado, Gloria Asensio-Juárez, Vanessa C Talayero, Miguel Vicente-Manzanares
The emergence of mechanobiology has unveiled complex mechanisms by which cells adjust intracellular force production to their needs. Most communicable intracellular forces are generated by myosin II, an actin-associated molecular motor that transforms adenosine triphosphate (ATP) hydrolysis into contraction in nonmuscle and muscle cells. Myosin II-dependent force generation is tightly regulated, and deregulation is associated with specific pathologies. Here, we focus on the role of myosin II (nonmuscle myosin II, NMII) in force generation and mechanobiology...
March 4, 2024: Current Opinion in Cell Biology
https://read.qxmd.com/read/38442043/an-opensim-based-closed-loop-biomechanical-wrist-model-for-subject-specific-pathological-tremor-simulation
#18
JOURNAL ARTICLE
Wellington C Pinheiro, Henrique B Ferraz, Maria Claudia F Castro, Luciano L Menegaldo
OBJECTIVE: A pathological tremor (PT) is an involuntary rhythmic movement of varying frequency and amplitude that affects voluntary motion, thus compromising individuals' independence. A comprehensive model incorporating PT's physiological and biomechanical aspects can enhance our understanding of the disorder and provide valuable insights for therapeutic approaches. This study aims to build a biomechanical model of pathological tremors using OpenSim's realistic musculoskeletal representation of the human wrist with two degrees of freedom...
March 5, 2024: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://read.qxmd.com/read/38440022/enhancing-athletic-performance-a-comprehensive-review-on-kettlebell-training
#19
REVIEW
Pratik R Jaiswal, Swapnil U Ramteke, Saylee Shedge
A kettlebell is a weight made of cast iron shaped like a ball with a handle. Commercial kettlebells are offered in capacities that vary from 3 pounds to 100 pounds (or more). The kettlebell has a variety of possible clinical applications, including dynamic flexibility exercises and power training. Players' efficacy during the game can be improved by developing their strongest potential prior to exercising and efficiently converting that strength to power as the event draws near. Strengthening has been recommended as an effective means to avoid injuries, build muscle strength, and enhance one's health in relation to performance in the game...
February 2024: Curēus
https://read.qxmd.com/read/38428633/an-update-on-the-cell-free-dna-derived-methylome-as-a-non-invasive-biomarker-for-coronary-artery-disease
#20
JOURNAL ARTICLE
Manoswini Dash, Bhawna Mahajan, Ghulam Mehdi Dar, Parameswar Sahu, Sundeep Singh Saluja
Cardiovascular diseases are the foremost contributor to global mortality, presenting a complex etiology and an expanding array of risk factors. Coronary artery disease characterized by atherosclerotic plaque build-up in the coronary arteries, imposes significant mortality and financial burdens, especially in low- and middle-income nations. The pathogenesis of coronary artery disease involves a multifaceted interplay of genetic, environmental, and epigenetic factors. Epigenetic regulation contributes to the dynamic control of gene expression without altering the underlying DNA sequence...
February 28, 2024: International Journal of Biochemistry & Cell Biology
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