keyword
MENU ▼
Read by QxMD icon Read
search

Horizontal DNA transfer

keyword
https://www.readbyqxmd.com/read/29143083/the-polyphyletic-origins-of-primase-helicase-bifunctional-proteins
#1
Ankita Gupta, Supriya Patil, Ramya Vijayakumar, Kiran Kondabagil
We studied the evolutionary relationships of different primase-helicase bifunctional proteins, found mostly in viruses, virophages, plasmids, and organellar genomes, by phylogeny and correlation analysis. Our study suggests independent origins of primase-helicase bifunctional proteins resulting from multiple fusion events between genes encoding primase and helicase domains of different families. The correlation analysis further indicated strong functional dependencies of domains in the bifunctional proteins that are part of smaller genomes and plasmids...
November 15, 2017: Journal of Molecular Evolution
https://www.readbyqxmd.com/read/29120392/impact-of-lateral-transfers-on-the-genomes-of-lepidoptera
#2
REVIEW
Jean-Michel Drezen, Thibaut Josse, Annie Bézier, Jérémy Gauthier, Elisabeth Huguet, Elisabeth Anne Herniou
Transfer of DNA sequences between species regardless of their evolutionary distance is very common in bacteria, but evidence that horizontal gene transfer (HGT) also occurs in multicellular organisms has been accumulating in the past few years. The actual extent of this phenomenon is underestimated due to frequent sequence filtering of "alien" DNA before genome assembly. However, recent studies based on genome sequencing have revealed, and experimentally verified, the presence of foreign DNA sequences in the genetic material of several species of Lepidoptera...
November 9, 2017: Genes
https://www.readbyqxmd.com/read/29120256/silent-but-deadly-is200-promotes-pathogenicity-in-salmonella-typhimurium
#3
Michael J Ellis, Lindsey A Carfrae, Craig R Macnair, Ryan S Trussler, Eric D Brown, David B Haniford
Bacterial transposons were long thought of as selfish mobile genetic elements that propagate at the expense of 'host' bacterium fitness. However, limited transposition can benefit the host organism by promoting DNA rearrangements and facilitating horizontal gene transfer. Here we discuss and provide context for our recently published work which reported the surprising finding that an otherwise dormant transposon, IS200, encodes a regulatory RNA in Salmonella Typhimurium. This previous work identified a trans-acting sRNA that is encoded in the 5'UTR of IS200 transposase mRNA (tnpA)...
November 9, 2017: RNA Biology
https://www.readbyqxmd.com/read/29116639/dna-replication-fidelity-in-the-mycobacterium-tuberculosis-complex
#4
Digby F Warner, Jeremy M Rock, Sarah M Fortune, Valerie Mizrahi
Mycobacterium tuberculosis is genetically isolated, with no evidence for horizontal gene transfer or the acquisition of episomal genetic information in the modern evolution of strains of the Mycobacterium tuberculosis complex. When considered in the context of the specific features of the disease M. tuberculosis causes (e.g., transmission via cough aerosol, replication within professional phagocytes, subclinical persistence, and stimulation of a destructive immune pathology), this implies that to understand the mechanisms ensuring preservation of genomic integrity in infecting mycobacterial populations is to understand the source of genetic variation, including the emergence of microdiverse sub-populations that may be linked to the acquisition of drug resistance...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29112165/poxvirus-host-range-genes-and-virus-host-spectrum-a-critical-review
#5
REVIEW
Graziele Pereira Oliveira, Rodrigo Araújo Lima Rodrigues, Maurício Teixeira Lima, Betânia Paiva Drumond, Jônatas Santos Abrahão
The Poxviridae family is comprised of double-stranded DNA viruses belonging to nucleocytoplasmic large DNA viruses (NCLDV). Among the NCLDV, poxviruses exhibit the widest known host range, which is likely observed because this viral family has been more heavily investigated. However, relative to each member of the Poxviridae family, the spectrum of the host is variable, where certain viruses can infect a large range of hosts, while others are restricted to only one host species. It has been suggested that the variability in host spectrum among poxviruses is linked with the presence or absence of some host range genes...
November 7, 2017: Viruses
https://www.readbyqxmd.com/read/29109705/complete-genome-sequence-of-vibrio-campbellii-lmb-29-isolated-from-red-drum-with-four-native-megaplasmids
#6
Jinxin Liu, Zhe Zhao, Yiqing Deng, Yan Shi, Yupeng Liu, Chao Wu, Peng Luo, Chaoqun Hu
Vibrio spp. are the most common pathogens for animals reared in aquaculture. Vibrio campbellii, which is often involved in shrimp, fish and mollusks diseases, is widely distributed in the marine environment worldwide, but our knowledge about its pathogenesis and antimicrobial resistance is very limited. The existence of this knowledge gap is at least partially because that V. campbellii was originally classified as Vibrio harveyi, and the detailed information of its comparative genome analysis to other Vibrio spp...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29101189/distribution-and-phylogeny-of-microsymbionts-associated-with-cowpea-vigna-unguiculata-nodulation-in-three-agro-ecological-regions-of-mozambique
#7
Ifeoma N Chidebe, Sanjay K Jaiswal, Felix D Dakora
Cowpea derives most of its N nutrition from biological nitrogen fixation (BNF) via symbiotic bacteroids in root nodules. In Sub-Saharan Africa, the diversity and biogeo-graphic distribution of bacterial microsymbionts nodulating cowpea and other indigenous legumes are not well understood, though needed for increased legume production. The aim of this study was to describe rhizobial distribution and their phylogenies at different agro-ecological regions of Mozambique using BOX-PCR, ITS-RFLP and sequence analysis of housekeeping genes...
November 3, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/29091031/inter-species-population-dynamics-enhance-microbial-horizontal-gene-transfer-and-spread-of-antibiotic-resistance
#8
Robert M Cooper, Lev Tsimring, Jeff Hasty
Horizontal gene transfer (HGT) plays a major role in the spread of antibiotic resistance. Of particular concern are Acinetobacter baumannii bacteria, which recently emerged as global pathogens, with nosocomial mortality rates reaching 19-54% (Centers for Disease Control and Prevention, 2013; Joly Guillou, 2005; Talbot et al., 2006). Acinetobacter gains antibiotic resistance remarkably rapidly (Antunes et al., 2014; Joly Guillou, 2005), with multi drug-resistance (MDR) rates exceeding 60% (Antunes et al., 2014; Centers for Disease Control and Prevention, 2013)...
November 1, 2017: ELife
https://www.readbyqxmd.com/read/29079617/staphylococcus-edaphicus-sp-nov-isolated-in-antarctica-harbours-mecc-gene-and-genomic-islands-with-suspected-role-in-adaptation-to-extreme-environment
#9
Roman Pantůček, Ivo Sedláček, Adéla Indráková, Veronika Vrbovská, Ivana Mašlaňová, Vojtěch Kovařovic, Pavel Švec, Stanislava Králová, Lucie Krištofová, Jana Kekláková, Petr Petráš, Jiří Doškař
Two Gram-stain-positive, coagulase-negative staphylococcal strains were isolated from abiotic sources, stone fragments and sandy soil in James Ross Island, Antarctica. Here we describe properties of novel species of the genus Staphylococcus that has near identical 16S rRNA gene sequence to Staphylococcus saprophyticus However, compared to S. saprophyticus and the next closest relatives, the new species demonstrates considerable phylogenetic distance at whole genome level, average nucleotide identity <85 %, and inferred DNA-DNA hybridization <30%...
October 27, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/29073103/packaging-and-transfer-of-mitochondrial-dna-via-exosomes-regulate-escape-from-dormancy-in-hormonal-therapy-resistant-breast-cancer
#10
Pasquale Sansone, Claudia Savini, Ivana Kurelac, Qing Chang, Laura Benedetta Amato, Antonio Strillacci, Anna Stepanova, Luisa Iommarini, Chiara Mastroleo, Laura Daly, Alexander Galkin, Basant Kumar Thakur, Nadine Soplop, Kunihiro Uryu, Ayuko Hoshinob, Larry Norton, Massimiliano Bonafé, Monica Cricca, Giuseppe Gasparre, David Lyden, Jacqueline Bromberg
The horizontal transfer of mtDNA and its role in mediating resistance to therapy and an exit from dormancy have never been investigated. Here we identified the full mitochondrial genome in circulating extracellular vesicles (EVs) from patients with hormonal therapy-resistant (HTR) metastatic breast cancer. We generated xenograft models of HTR metastatic disease characterized by EVs in the peripheral circulation containing mtDNA. Moreover, these human HTR cells had acquired host-derived (murine) mtDNA promoting estrogen receptor-independent oxidative phosphorylation (OXPHOS)...
October 24, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29069493/horizontal-transfer-of-non-ltr-retrotransposons-from-arthropods-to-flowering-plants
#11
Dongying Gao, Ye Chu, Han Xia, Chunming Xu, Karolina Heyduk, Brian Abernathy, Peggy Ozias-Akins, James H Leebens-Mack, Scott A Jackson
Even though lateral movements of transposons across families and even phyla within multicellular eukaryotic kingdoms have been found, little is known about transposon transfer between the kingdoms Animalia and Plantae. We discovered a novel non-LTR retrotransposon, AdLINE3, in a wild peanut species. Sequence comparisons and phylogenetic analyses indicated that AdLINE3 is a member of the RTE clade, originally identified in a nematode and rarely reported in plants. We identified RTE elements in 82 plants, spanning angiosperms to algae, including recently active elements in some flowering plants...
October 23, 2017: Molecular Biology and Evolution
https://www.readbyqxmd.com/read/29055834/long-term-industrial-metal-contamination-unexpectedly-shaped-diversity-and-activity-response-of-sediment-microbiome
#12
Samuel Jacquiod, Valentine Cyriaque, Leise Riber, Waleed Abu Al-Soud, David C Gillan, Ruddy Wattiez, Søren J Sørensen
Metal contamination poses serious biotoxicity and bioaccumulation issues, affecting both abiotic conditions and biological activity in ecosystem trophic levels, especially sediments. The MetalEurop foundry released metals directly into the French river "la Deûle" during a century, contaminating sediments with a 30-fold increase compared to upstream unpolluted areas (Férin, Sensée canal). Previous metaproteogenomic work revealed phylogenetically analogous, but functionally different microbial communities between the two locations...
September 28, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/29042411/a-horizontally-transferred-autonomous-helitron-became-a-full-polydnavirus-segment-in-cotesia-vestalis
#13
Pedro Heringer, Guilherme B Dias, Gustavo C S Kuhn
Bracoviruses associate symbiotically with thousands of parasitoid wasp species in the family Braconidae, working as virulence gene vectors, and allowing the development of wasp larvae within hosts. These viruses are composed by multiple DNA circles that are packaged into infective particles and injected together with wasp's eggs during parasitization. One of the viral segments of Cotesia vestalis bracovirus contains a gene that has been previously described as a helicase of unknown origin. Here we demonstrate that this gene is a Rep/Helicase from an intact Helitron transposable element that covers the viral segment almost entirely...
October 17, 2017: G3: Genes—Genomes—Genetics
https://www.readbyqxmd.com/read/29041914/analysis-of-the-genome-of-the-new-zealand-giant-collembolan-holacanthella-duospinosa-sheds-light-on-hexapod-evolution
#14
Chen Wu, Melissa D Jordan, Richard D Newcomb, Neil J Gemmell, Sarah Bank, Karen Meusemann, Peter K Dearden, Elizabeth J Duncan, Sefanie Grosser, Kim Rutherford, Paul P Gardner, Ross N Crowhurst, Bernd Steinwender, Leah K Tooman, Mark I Stevens, Thomas R Buckley
BACKGROUND: The New Zealand collembolan genus Holacanthella contains the largest species of springtails (Collembola) in the world. Using Illumina technology we have sequenced and assembled a draft genome and transcriptome from Holacanthella duospinosa (Salmon). We have used this annotated assembly to investigate the genetic basis of a range of traits critical to the evolution of the Hexapoda, the phylogenetic position of H. duospinosa and potential horizontal gene transfer events. RESULTS: Our genome assembly was ~375 Mbp in size with a scaffold N50 of ~230 Kbp and sequencing coverage of ~180×...
October 17, 2017: BMC Genomics
https://www.readbyqxmd.com/read/29030446/comparative-genomics-based-markers-discrimination-of-host-specificity-in-fusarium-oxysporum
#15
Peter van Dam, Mara de Sain, Anneliek Ter Horst, Michelle van der Gragt, Martijn Rep
The polyphyletic nature of many formae speciales of Fusarium oxysporum (Fo) prevents molecular identification of newly encountered strains based on conserved, vertically inherited genes. Alternative molecular detection methods that could replace labour- and time-intensive disease assays are therefore highly desired. Effectors are functional elements in the pathogen-host interaction and have been found to show very limited sequence diversity between strains of the same forma specialis, which makes them potential markers for host-specific pathogenicty...
October 13, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/29018417/molecular-mechanisms-that-contribute-to-horizontal-transfer-of-plasmids-by-the-bacteriophage-spp1
#16
Ana Valero-Rello, María López-Sanz, Alvaro Quevedo-Olmos, Alexei Sorokin, Silvia Ayora
Natural transformation and viral-mediated transduction are the main avenues of horizontal gene transfer in Firmicutes. Bacillus subtilis SPP1 is a generalized transducing bacteriophage. Using this lytic phage as a model, we have analyzed how viral replication and recombination systems contribute to the transfer of plasmid-borne antibiotic resistances. Phage SPP1 DNA replication relies on essential phage-encoded replisome organizer (G38P), helicase loader (G39P), hexameric replicative helicase (G40P), recombinase (G35P) and in less extent on the partially dispensable 5'→3' exonuclease (G34...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28956406/-aide-encodes-an-n-acyl-homoserine-lactonase-in-acinetobacter
#17
Chunyan Liu, Song Guo, Ali Turak, Junwei Zhang, Liqun Zhang
Quorum sensing (QS) is a cell-cell communication mechanism that allows bacterial populations to coordinate gene expression in response to cell density. N-acylhomoserine lactones (AHL) are used as quorum-sensing signal molecules by many Gram negative bacteria. Acinetobacter sp. 77, an AHL-degrading bacterium, was isolated in our previous work. The gene aidE for AHL inactivation was cloned in this study by screening a genomic DNA library. The deduced protein AidE is 268 amino acids in length and shares a high identity (95%) with the beta-lactamase family protein in Acinetobacter gyllenbergii CIP110306, but low identities with known AHL-degrading enzymes...
September 25, 2017: Sheng Wu Gong Cheng Xue Bao, Chinese Journal of Biotechnology
https://www.readbyqxmd.com/read/28956196/novel-bacteria-capable-of-degrading-phenanthrene-in-activated-sludge-revealed-by-stable-isotope-probing-coupled-with-high-throughput-sequencing
#18
Jibing Li, Dayi Zhang, Mengke Song, Longfei Jiang, Yujie Wang, Chunling Luo, Gan Zhang
The indigenous microorganisms responsible for degrading phenanthrene (PHE) in activated biosludge were identified using DNA-based stable isotope probing. Besides the well-known PHE degraders Burkholderia, Ralstonia, Sinobacteraceae and Arthrobacter, we for the first time linked the taxa Paraburkholderia and Kaistobacter with in situ PHE biodegradation. Analysis of PAH-RHDα gene detected in the heavy DNA fraction of (13)C-PHE treatment suggested the mechanisms of horizontal gene transfer or inter-species hybridisation in PAH-RHD gene spread within the microbial community...
September 27, 2017: Biodegradation
https://www.readbyqxmd.com/read/28932624/staphylococci-on-ice-overlooked-agents-of-horizontal-gene-transfer
#19
REVIEW
Emily A Sansevere, D Ashley Robinson
Horizontal gene transfer plays a significant role in spreading antimicrobial resistance and virulence genes throughout the genus Staphylococcus, which includes species of clinical relevance to humans and animals. While phages and plasmids are the most well-studied agents of horizontal gene transfer in staphylococci, the contribution of integrative conjugative elements (ICEs) has been mostly overlooked. Experimental work demonstrating the activity of ICEs in staphylococci remained frozen for years after initial work in the 1980s that showed Tn916 was capable of transfer from Enterococcus to Staphylococcus...
2017: Mobile Genetic Elements
https://www.readbyqxmd.com/read/28929030/genomic-analysis-of-p-elements-in-natural-populations-of-drosophila-melanogaster
#20
Casey M Bergman, Shunhua Han, Michael G Nelson, Vladyslav Bondarenko, Iryna Kozeretska
The Drosophila melanogaster P transposable element provides one of the best cases of horizontal transfer of a mobile DNA sequence in eukaryotes. Invasion of natural populations by the P element has led to a syndrome of phenotypes known as P-M hybrid dysgenesis that emerges when strains differing in their P element composition mate and produce offspring. Despite extensive research on many aspects of P element biology, many questions remain about the genomic basis of variation in P-M dysgenesis phenotypes across populations...
2017: PeerJ
keyword
keyword
74169
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"