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developmental embryology

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https://www.readbyqxmd.com/read/28818334/the-use-of-acupuncture-in-first-aid-of-burns-clinical-report
#1
A Loskotova, J Loskotova
Burns are a very painful skin injury, or injury of soft tissues. The development of post-traumatic stress disorder can develop, even in those with minor injuries (Ia-IIb degree). Development of problems is very rapid and intense since, according to developmental embryology, the skin and central nervous system (CNS) descend from the same germ layer-ectoderm. This clinical report presents the results acquired from the data of 1008 patients suffering from burns treated by the acupuncture (ACU)-from 1983-2015 in the surgery ward of the hospital in Vysoke Myto in the Czech Republic...
August 14, 2017: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/28808898/wilhelm-his-and-mechanistic-approaches-to-development-at-the-time-of-entwicklungsmechanik
#2
Jean-Claude Dupont
At the end of the nineteenth century, approaches from experimental physiology made inroads into embryological research. A new generation of embryologists felt urged to study the mechanisms of organ formation. This new program, most prominently defended by Wilhelm Roux (1850-1924), was called Entwicklungsmechanik. Named variously as "causal embryology", "physiological embryology" or "developmental mechanics", it catalyzed the movement of embryology from a descriptive science to one exploring causal mechanisms...
August 14, 2017: History and Philosophy of the Life Sciences
https://www.readbyqxmd.com/read/28807504/bone-up-craniomandibular-development-and-hard-tissue-biomineralization-in-neonate-mice
#3
Khari D Thompson, Holly E Weiss-Bilka, Elizabeth B McGough, Matthew J Ravosa
The presence of regional variation in the osteogenic abilities of cranial bones underscores the fact that the mechanobiology of the mammalian skull is more complex than previously recognized. However, the relationship between patterns of cranial bone formation and biomineralization remains incompletely understood. In four strains of mice, micro-computed tomography was used to measure tissue mineral density during perinatal development in three skull regions (calvarium, basicranium, mandible) noted for variation in loading environment, embryological origin, and ossification mode...
January 29, 2017: Zoology: Analysis of Complex Systems, ZACS
https://www.readbyqxmd.com/read/28764139/atlantooccipital-fusion-prevalence-and-its-developmental-and-clinical-correlation
#4
D K Sharma, Deepak Sharma, Vandana Sharma
INTRODUCTION: Atlantooccipital fusion or occipitalization of atlas or assimilation of atlas is a rare or uncommon abnormality recorded in anatomical, morphological and radiological studies. It is usually associated with reduction in dimensions of foramen magnum leading to acute or chronic neurovascular compression and clinical manifestations of varying severity. Though, atlantooccipital fusion is rare but it is important and significant for the physicians and surgeons for their diagnostic and therapeutic approach...
June 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28757335/imaging-in-cutis-laxa-syndrome-caused-by-a-dominant-negative-aldh18a1-mutation-with-hypotheses-for-intracranial-vascular-tortuosity-and%C3%A2-wide-perivascular-spaces
#5
P F Sinnige, C M A van Ravenswaaij-Arts, P Caruso, A E Lin, M Boon, E Rahikkala, B Callewaert, L C Meiners
The autosomal dominant progeroid form of cutis laxa is a recently identified multiple congenital anomaly disorder characterized by thin, wrinkled skin, a progeroid appearance, intra-uterine growth retardation, postnatal growth restriction, psychomotor developmental delay, microcephaly, cataract, hypotonia and contractures. De novo heterozygous mutations in ALDH18A1 have been described in this condition. We present neuroimaging abnormalities in three patients. One patient had intracranial arterial and venous tortuosity, widened ventricular and extra-axial cerebrospinal fluid (CSF) spaces, wide perivascular spaces and increased T2 signal intensity in the cerebral white matter over time...
July 18, 2017: European Journal of Paediatric Neurology: EJPN
https://www.readbyqxmd.com/read/28734068/evolution-of-antero-posterior-patterning-of-the-limb-insights-from-the-chick
#6
REVIEW
Matthew Towers
The developing limbs of chicken embryos have served as pioneering models for understanding pattern formation for over a century. The ease with which chick wing and leg buds can be experimentally manipulated, while the embryo is still in the egg, has resulted in the discovery of important developmental organisers, and subsequently, the signals that they produce. Sonic hedgehog (Shh) is produced by mesenchyme cells of the polarizing region at the posterior margin of the limb bud and specifies positional values across the antero-posterior axis (the axis running from the thumb to the little finger)...
July 22, 2017: Genesis: the Journal of Genetics and Development
https://www.readbyqxmd.com/read/28698706/personhood-status-of-the-human-zygote-embryo-fetus
#7
John Janez Miklavcic, Paul Flaman
The fields of biology, medicine, and embryology have described the developmental milestones of humans throughout gestation in great detail. It is less clear as to when humans are recognized as people, persons, or beings with rights that are protected by legislation. The practice of law is irrevocably intertwined with that of ethical conduct; and the time at which a human life is considered a person has implications that extend to health care, legislation on abortion, and autonomy of individuals. This article reviews the economical position that fertilization is the moment that personhood of the conceptus begins...
May 2017: Linacre Quarterly
https://www.readbyqxmd.com/read/28695964/segmentation-gene-expression-patterns-in-bactrocera-dorsalis-and-related-insects-regulation-and-shape-of-blastoderm-and-larval-cuticle
#8
Worramin Suksuwan, Xiaoli Cai, Lertluk Ngernsiri, Stefan Baumgartner
The oriental fruit fly, Bactrocera dorsalis, is regarded as a severe pest of fruit production in Asia. Despite its economic importance, only limited information regarding the molecular and developmental biology of this insect is known to date. We provide a detailed analysis of B. dorsalis embryology, as well as the expression patterns of a number of segmentation genes known to act during patterning of Drosophila and compare these to the patterns of other insect families. An anterior shift of the expression of gap genes was detected when compared to Drosophila...
2017: International Journal of Developmental Biology
https://www.readbyqxmd.com/read/28673936/targeting-the-hepatocyte-growth-factor-met-pathway-in-cancer
#9
REVIEW
Dinuka M De Silva, Arpita Roy, Takashi Kato, Fabiola Cecchi, Young H Lee, Kunio Matsumoto, Donald P Bottaro
Hepatocyte growth factor (HGF)-induced activation of its cell surface receptor, the Met tyrosine kinase, drives mitogenesis, motogenesis and morphogenesis in a wide spectrum of target cell types and embryologic, developmental and homeostatic contexts. Typical paracrine HGF/Met signaling is regulated by HGF activation at target cell surfaces, HGF binding-induced receptor activation, internalization and degradation. Despite these controls, HGF/Met signaling contributes to oncogenesis, tumor angiogenesis and invasiveness, and tumor metastasis in many types of cancer, leading to the rapid growth of pathway-targeted anticancer drug development programs...
August 15, 2017: Biochemical Society Transactions
https://www.readbyqxmd.com/read/28669817/deep-ancestry-of-programmed-genome-rearrangement-in-lampreys
#10
Vladimir A Timoshevskiy, Ralph T Lampman, Jon E Hess, Laurie L Porter, Jeramiah J Smith
In most multicellular organisms, the structure and content of the genome is rigorously maintained over the course of development. However some species have evolved genome biologies that permit, or require, developmentally regulated changes in the physical structure and content of the genome (programmed genome rearrangement: PGR). Relatively few vertebrates are known to undergo PGR, although all agnathans surveyed to date (several hagfish and one lamprey: Petromyzon marinus) show evidence of large scale PGR...
September 1, 2017: Developmental Biology
https://www.readbyqxmd.com/read/28668160/mr-imaging-of-m%C3%A3-llerian-fusion-anomalies
#11
REVIEW
Jeffrey D Olpin, Aida Moeni, Roderick J Willmore, Marta E Heilbrun
Müllerian duct anomalies, also called congenital uterine anomalies, are developmental structural disorders of the female genital tract. These anomalies are clinically relevant in patients with a history of infertility and pregnancy-related complications. The American Society for Reproductive Medicine classification system is the most well known, although newer systems, such as from the European Society of Human Reproduction and Embryology/European Society for Gynaecological Endoscopy, are becoming more widely accepted...
August 2017: Magnetic Resonance Imaging Clinics of North America
https://www.readbyqxmd.com/read/28658972/programming-microphysiological-systems-for-children-s-health-protection
#12
T B Knudsen, B Klieforth, W Slikker
Microphysiological systems (MPS) and computer simulation models that recapitulate the underlying biology and toxicology of critical developmental transitions are emerging tools for developmental effects assessment of drugs/chemicals. Opportunities and challenges exist for their application to alternative, more public health relevant and efficient chemical toxicity testing methods. This is especially pertinent to children's health research and the evaluation of complex embryological and reproductive impacts of drug/chemical exposure...
January 1, 2017: Experimental Biology and Medicine
https://www.readbyqxmd.com/read/28643263/genome-editing-of-the-ascidian-ciona-intestinalis-with-tale-nuclease
#13
Yasunori Sasakura, Keita Yoshida, Nicholas Treen
The ascidian Ciona intestinalis is an important model animal for studying developmental mechanisms for constructing the chordate body. Although molecular and embryological techniques for manipulating Ciona genes were developed a long time ago, recent achievements of genome editing in this animal have innovated functional analyses of genes in Ciona. Particularly, knockout of genes in the G0 generation coupled with tissue-specific expression of TALENs enables us to rapidly address gene functions that were difficult using previous methods...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28621409/hefzibah-eyal-giladi-1925-2017-over-fifty-years-of-embryological-research-in-israel
#14
Oded Khaner
Hefzibah Eyal-Giladi was a creative and innovative pioneering scientist in the creation of the field of early chick embryo development. She had a sharp thinking and enthusiastic attitude, which enabled her to make a deep impression that was highly valued by the general scientific community. Notably, she was a highly successful female researcher in an era which was dominated by male scientists. Her unique personality and keen intellect enabled her to break these borders in a most successful manner. The experiments conducted by her personally, her students and her collaborators served to provide the basic knowledge and paradigms for future scientists in the field, also paving the way for discoveries in other vertebrate model systems...
2017: International Journal of Developmental Biology
https://www.readbyqxmd.com/read/28620997/morphology-and-evolution-of-the-oral-shield-in-marsupial-neonates-including-the-newborn-monito-del-monte-dromiciops-gliroides-marsupialia-microbiotheria-pouch-young
#15
Nanette Y Schneider, Yamila Gurovich
Newborn marsupials can be arranged into three grades of developmental complexity based on their external form, as well as based on their organ systems and their cytology. The dasyurids are considered the least developed marsupials at birth, while didelphids and peramelids are intermediate, and macropods are the most developed. Currently there is still little information on caenolestid and microbiotherid development at birth. Developmental stages can be graded as G1, G2 and G3, with G1 being the least developed at birth, and G3 the most developed...
July 2017: Journal of Anatomy
https://www.readbyqxmd.com/read/28612426/embryology-and-pathophysiology-of-the-chiari-i-and-ii-malformations-a-comprehensive-review
#16
REVIEW
Mohammadali M Shoja, Jaspreet Johal, W Jerry Oakes, R Shane Tubbs
Although the Chiari malformations are well-studied and described developmental anomalies, there remains some incongruity in regards to their underlying etiologies. A number of theories have been proposed with the purpose of accounting for the embryology and pathogenesis of the Chiari I and II malformations and their associated complications and clinical syndromes. The present review aims to review the pertinent literature for all of the main theories that have been proposed, and outline their validity and relevance to our contemporary understanding of these anomalies...
June 13, 2017: Clinical Anatomy
https://www.readbyqxmd.com/read/28602826/an-alternative-didactic-functional-and-topographic-systematization-of-the-spinal-muscles
#17
Vivianne Izabelle de Araújo Baptista, William Paganini Mayer, Ricardo Eustáquio da Silva, Ricardo Bragança de Vasconcellos Fontes, Josemberg da Silva Baptista
Back muscles are commonly described in a topographically-oriented manner without necessarily following morphological criteria. In this manner, non-standard terms may be employed which convey incorrect morphological concepts and demanding more time from both faculty and students to transmit knowledge. We propose a classification system for spinal muscles incorporating morphological concepts with the goal of facilitating knowledge transfer and suggest the term "spinal muscles". Those muscles were systematically divided and classified in seven strata from anterior to posterior: vertebro-appendicular (VA), transversarium (Tr), deep post-transversarium (DPT), middle post-transversarium (MPT), superficial post-transversarium (SPT), deep spino-appendicular (DSA) and superficial spino-appendicular (SSA)...
September 2017: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
https://www.readbyqxmd.com/read/28592182/perioperative-and-anesthetic-considerations-in-atrioventricular-septal-defect
#18
Faith J Ross, Viviane G Nasr, Denise Joffe, Gregory J Latham
Atrioventricular septal defect results from a failure of normal endocardial cushion fusion during embryologic cardiac development. This developmental aberration results in defects in the atrial and/or ventricular septum and malformation of the atrioventricular valves. The pathophysiology of atrioventricular septal defect is variable, and ranges from mild left to right shunting similar to a simple atrial septal defect to complex single-ventricle heart disease. This review focuses on the spectrum of atrioventricular septal defect from partial to complete, without associated cardiac defects...
September 2017: Seminars in Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/28553657/cancer-is-to-embryology-as-mutation-is-to-genetics-hypothesis-of-the-cancer-as-embryological-phenomenon
#19
REVIEW
Jaime Cofre, Eliana Abdelhay
Despite numerous advances in cell biology, genetics, and developmental biology, cancer origin has been attributed to genetic mechanisms primarily involving mutations. Embryologists have expressed timidly cancer embryological origin with little success in leveraging the discussion that cancer could involve a set of conventional cellular processes used to build the embryo during morphogenesis. Thus, this "cancer process" allows the harmonious and coherent construction of the embryo structural base, and its implementation as the embryonic process involves joint regulation of differentiation, proliferation, cell invasion, and migration, enabling the human being recreation of every generation...
2017: TheScientificWorldJournal
https://www.readbyqxmd.com/read/28548230/molecular-basis-of-social-competence-in-medaka-fish
#20
REVIEW
Teruhiro Okuyama, Saori Yokoi, Hideaki Takeuchi
Oryzias latipes (Medaka) is an established vertebrate model for studying developmental genetics, genomics, and evolutionary biology. The physiology, embryology, and genetics of this species have been extensively investigated for centuries. Medaka fish recently attracted attention in the field of social neuroscience. This review introduces recent advances in medaka behavioral studies, focusing on female mating preferences and male mate-guarding behaviors. The medaka female has the ability to discriminate male individuals and prefers to mate with socially familiar males (female mating preference)...
May 26, 2017: Development, Growth & Differentiation
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