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https://www.readbyqxmd.com/read/16573614/specific-autologous-cytotoxic-t-lymphocytes-for-chronic-varicella-in-a-liver-transplanted-child
#1
Maria Luisa Melzi, Aurelio Sonzogni, Patrizia Comoli, Paola Stroppa, Silvia Riva, Monica Altobelli, Annalia Casati, Giuliano Torre, Daniele Alberti, Michela Guizzetti, Milena Furione, Marco Spada, Michele Colledan, Bruno Gridelli
Infections by herpesviruses may have severe complications in liver transplant patients. Although prophylactic varicella zoster virus vaccination is strongly recommended and widely applied, severe infection may still occur. We report the case of systemic chronic varicella, which developed in a liver allograft recipient, unresponsive to antiviral drug treatment, successfully treated by varicella zooster-specific CTL. Graft failure ensued, likely, because of massive cytolysis of infected hepatocytes. The patient, who was re-transplanted in the absence of signs of varicella zooster reactivation, is now well and disease free 3 yr after second liver transplant...
March 2006: Pediatric Transplantation
https://www.readbyqxmd.com/read/10488675/chronic-motor-cortex-stimulation-in-the-treatment-of-central-and-neuropathic-pain-correlations-between-clinical-electrophysiological-and-anatomical-data
#2
COMPARATIVE STUDY
J P Nguyen, J P Lefaucheur, P Decq, T Uchiyama, A Carpentier, D Fontaine, P Brugières, B Pollin, A Fève, S Rostaing, P Cesaro, Y Keravel
Thirty-two patients with refractory central and neuropathic pain of peripheral origin were treated by chronic stimulation of the motor cortex between May 1993 and January 1997. The mean follow-up was 27.3 months. The first 24 patients were operated according to the technique described by Tsubokawa. The last 13 cases (eight new patients and five reinterventions) were operated by a technique including localisation by superficial CT reconstruction of the central region and neuronavigator guidance. The position of the central sulcus was confirmed by the use of intraoperative somatosensory evoked potentials...
September 1999: Pain
https://www.readbyqxmd.com/read/577377/immunosuppression-role-on-the-infectious-diseases-of-oncologic-children
#3
V Castel, J Ferris, A Verdeguer
Cancer patients show an immune deficit whose beginnings are influenced to one extent or another, by two factors: the cancer itself, and the antimitotic-immunosuppressive treatment to which the patient is subjected. The immune deficit will have repercussions in the anti-infectious defense that these patients show: --Greater number of infections. --Greater severity of infections. --Tendency towards generalization and showing of septicemic states. The problem is most serious in hematological tumors (leukemia, lymphosarcoma) where the primary cause of death is infection...
January 1977: Allergologia et Immunopathologia
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