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https://www.readbyqxmd.com/read/28437292/use-of-electronic-consultation-system-to-improve-access-to-care-in-pediatric-hematology-oncology
#1
Donna L Johnston, Kimmo Murto, Julia Kurzawa, Clare Liddy, Erin Keely, Lillian Lai
BACKGROUND: Electronic consultations (eConsult) allow for communication between primary care providers and specialists in an asynchronous manner. This study examined provider satisfaction, topics of interest, and efficiency of eConsult in pediatric hematology/oncology in Ottawa, Canada. METHODS: We conducted a cross-sectional assessment of all eConsult cases directed to pediatric hematology/oncology specialists using the Champlain BASE (Building Access to Specialists through eConsultation) eConsult service from June 1, 2014 to May 31, 2016...
April 21, 2017: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/28434482/how-to-implement-clinical-guidelines-to-optimise-familial-hypercholesterolaemia-diagnosis-and-treatment
#2
Michel Farnier, Fernando Civeira, Olivier Descamps
BACKGROUND AND AIMS: Familial hypercholesterolaemia (FH) is a genetic disorder associated with significantly elevated plasma low-density lipoprotein cholesterol (LDL-C) and premature coronary heart disease (CHD). Optimal management of FH relies on early identification and treatment with statins alone or in combination with other lipid-lowering therapies. A lack of awareness of FH and its manifestations among primary care physicians and specialists has led to many individuals being misdiagnosed in the early stages of the disease, further increasing the risk of CHD and requiring much more intensive lipid-lowering strategies...
April 2017: Atherosclerosis. Supplements
https://www.readbyqxmd.com/read/28433857/the-relationship-between-joint-attention-and-theory-of-mind-in-neurotypical-adults
#3
Jordan A Shaw, Lauren K Bryant, Bertram F Malle, Daniel J Povinelli, John R Pruett
Joint attention (JA) is hypothesized to have a close relationship with developing theory of mind (ToM) capabilities. We tested the co-occurrence of ToM and JA in social interactions between adults with no reported history of psychiatric illness or neurodevelopmental disorders. Participants engaged in an experimental task that encouraged nonverbal communication, including JA, and also ToM activity. We adapted an in-lab variant of experience sampling methods (Bryant et al., 2013) to measure ToM during JA based on participants' subjective reports of their thoughts while performing the task...
April 20, 2017: Consciousness and Cognition
https://www.readbyqxmd.com/read/28433195/predicting-successful-dental-examinations-for-children-with-autism-spectrum-disorder-in-the-context-of-a-dental-desensitization-program
#4
Travis Nelson, Amelia Chim, Barbara L Sheller, Christy M McKinney, JoAnna M Scott
BACKGROUND: The authors evaluated the effectiveness of a dental desensitization program for children with autism spectrum disorder (ASD) and determined characteristics associated with a successful dental examination. METHODS: The authors performed a retrospective review of clinical behavioral data and previsit questionnaires for 168 children with ASD who attended a university-based dental desensitization program. Data elements included demographic, treatment, and behavioral characteristics...
April 19, 2017: Journal of the American Dental Association
https://www.readbyqxmd.com/read/28432040/usability-acceptability-and-adherence-to-an-electronic-self-monitoring-system-in-patients-with-major-depression-discharged-from-inpatient-wards
#5
Lise Lauritsen, Louise Andersen, Emilia Olsson, Stine Rauff Søndergaard, Lasse Benn Nørregaard, Philip Kaare Løventoft, Signe Dunker Svendsen, Erik Frøkjær, Hans Mørch Jensen, Ida Hageman, Lars Vedel Kessing, Klaus Martiny
BACKGROUND: Patients suffering from depression have a high risk of relapse and readmission in the weeks following discharge from inpatient wards. Electronic self-monitoring systems that offer patient-communication features are now available to offer daily support to patients, but the usability, acceptability, and adherence to these systems has only been sparsely investigated. OBJECTIVE: We aim to test the usability, acceptability, adherence, and clinical outcome of a newly developed computer-based electronic self-assessment system (the Daybuilder system) in patients suffering from depression, in the period from discharge until commencing outpatient treatment in the Intensive Outpatient Unit for Affective Disorders...
April 21, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28429620/physician-perspectives-on-decision-making-for-treatment-of-pediatric-sleep-disordered-breathing
#6
Emily F Boss, Anne R Links, Ron Saxton, Tina L Cheng, Mary Catherine Beach
Sleep-disordered breathing (SDB) is prevalent in children and most commonly treated by surgery with adenotonsillectomy. We aimed to learn physician perspectives of social and communication factors that influence decision making for treatment of pediatric SDB. Purposive sampling identified 10 physician key informants across disciplines and practice settings, who participated in semistructured interviews regarding SDB care experiences and communication with parents. Interviews were analyzed using directed qualitative content analysis...
April 1, 2017: Clinical Pediatrics
https://www.readbyqxmd.com/read/28429618/the-clinician-perspective-on-sex-differences-in-autism-spectrum-disorders
#7
Rene Jamison, Somer L Bishop, Marisela Huerta, Alycia K Halladay
Research studies using existing samples of individuals with autism spectrum disorders have identified differences in symptoms between males and females. Differences are typically reported in school age and adolescence, with similarities in symptom presentation at earlier ages. However, existing studies on sex differences are significantly limited, making it challenging to discern if, how, and at what point in development females with autism spectrum disorder actually exhibit a different behavioral presentation than males...
April 1, 2017: Autism: the International Journal of Research and Practice
https://www.readbyqxmd.com/read/28428247/induction-of-cell-death-and-gain-of-function-properties-of-connexin26-mutants-predict-severity-of-skin-disorders-and-hearing-loss
#8
Eric R Press, Qing Shao, John J Kelly, Katrina Chin, Anton Alaga, Dale W Laird
Connexin26 (Cx26) is a gap junction protein that oligomerizes in the cell to form hexameric transmembrane channels called connexons. Cell surface connexons dock between adjacent cells to allow for gap junctional intercellular communication. Numerous autosomal dominant mutations in the Cx26 encoding GJB2 gene lead to many skin disorders and sensorineural hearing loss. Although some insights have been gained into the pathogenesis of these diseases, it is not fully understood how distinct GJB2 mutations result in hearing loss alone or in skin pathologies with comorbid hearing loss...
April 20, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/28427562/cardiokines-as-modulators-of-stress-induced-cardiac-disorders
#9
Anna Planavila, Joaquim Fernández-Solà, Francesc Villarroya
Almost 30 years ago, the protein, atrial natriuretic peptide, was identified as a heart-secreted hormone that provides a peripheral signal from the myocardium that communicates to the rest of the organism to modify blood pressure and volume under conditions of heart failure. Since then, additional peripheral factors secreted by the heart, termed cardiokines, have been identified and shown to coordinate this interorgan cross talk. In addition to this interorgan communication, cardiokines also act in an autocrine/paracrine manner to play a role in intercellular communication within the myocardium...
2017: Advances in Protein Chemistry and Structural Biology
https://www.readbyqxmd.com/read/28425776/development-of-the-aboriginal-communication-assessment-after-brain-injury-acaabi-a-screening-tool-for-identifying-acquired-communication-disorders-in-aboriginal-australians
#10
Elizabeth M Armstrong, Natalie Ciccone, Deborah Hersh, Judith Katzenellebogen, Juli Coffin, Sandra Thompson, Leon Flicker, Colleen Hayward, Deborah Woods, Meaghan McAllister
PURPOSE: Acquired communication disorders (ACD), following stroke and traumatic brain injury, may not be correctly identified in Aboriginal Australians due to a lack of linguistically and culturally appropriate assessment tools. Within this paper we explore key issues that were considered in the development of the Aboriginal Communication Assessment After Brain Injury (ACAABI) - a screening tool designed to assess the presence of ACD in Aboriginal populations. METHOD: A literature review and consultation with key stakeholders were undertaken to explore directions needed to develop a new tool, based on existing tools and recommendations for future developments...
February 21, 2017: International Journal of Speech-language Pathology
https://www.readbyqxmd.com/read/28425759/speech-pathology-as-the-masterchef-getting-the-right-ingredients-and-stirring-the-pot
#11
Pam Enderby
The purpose of this paper is to consider the many influences that have an impact on appropriate speech-language pathology service delivery. The competitive cooking and entertainment television program, MasterChef, is used as an analogy to consider the ingredients, blend and approach required to improve speech-language pathology services. Speech-language pathologists (SLPs) enter the profession with the aim of assisting those with communication and swallowing disorders to have a better quality of life. Thus, we should be restless to continue to improve our services in order to achieve the best influence and outcomes by changing our recipes and ingredients...
February 16, 2017: International Journal of Speech-language Pathology
https://www.readbyqxmd.com/read/28424068/efficacy-of-a-transdiagnostic-internet-based-treatment-for-emotional-disorders-with-a-specific-component-to-address-positive-affect-study-protocol-for-a-randomized-controlled-trial
#12
Amanda Díaz-García, Alberto González-Robles, Javier Fernández-Álvarez, Azucena García-Palacios, Rosa María Baños, Cristina Botella
BACKGROUND: Emotional disorders (ED) are among the most prevalent mental disorders. However, less than 50% of people suffering from ED receive the appropriate treatment. This situation has led to the development of new intervention proposals based on the transdiagnostic perspective, which tries to address the underlying processes common to ED. Most of these programs focus primarily on down-regulating negative affectivity, rather than increasing strengths and up-regulating positive affectivity...
April 20, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28422133/gene-set-analysis-shows-association-between-fmrp-targets-and-autism-spectrum-disorder
#13
Arija Jansen, Gwen C Dieleman, August B Smit, Matthijs Verhage, Frank C Verhulst, Tinca J C Polderman, Danielle Posthuma
Autism spectrum disorder (ASD) is a heterogeneous group of disorders characterized by problems with social interaction, communication, and repetitive and restricted behavior. Despite its high heritability and the substantial progress made in elucidating genetic associations, the corresponding biological mechanisms are largely unknown. Our objective is to investigate the contribution of common genetic variation to biological pathways functionally involved in ASD. We conducted gene-set analyses to identify ASD-associated functional biological pathways using the statistical tools MAGMA and INRICH...
April 19, 2017: European Journal of Human Genetics: EJHG
https://www.readbyqxmd.com/read/28421707/content-analysis-of-the-professional-journal-of-the-royal-college-of-speech-and-language-therapists-iii-1966-2015-into-the-21st-century
#14
Linda Armstrong, Jois Stansfield, Steven Bloch
BACKGROUND: Following content analyses of the first 30 years of the UK speech and language therapy professional body's journal, this study was conducted to survey the published work of the speech (and language) therapy profession over the last 50 years and trace key changes and themes. AIM: To understand better the development of the UK speech and language therapy profession over the last 50 years. METHODS & PROCEDURES: All volumes of the professional journal of the Royal College of Speech and Language Therapists published between 1966 and 2015 (British Journal of Communication Disorders, European Journal of Communication Disorders and International Journal of Language and Communication Disorders) were examined using content analysis...
April 18, 2017: International Journal of Language & Communication Disorders
https://www.readbyqxmd.com/read/28421695/evaluation-of-an-interview-skills-training-package-for-adolescents-with-speech-language-and-communication-needs
#15
Rachel Mathrick, Tina Meagher, Courtenay Frazier Norbury
BACKGROUND & AIMS: We evaluated a structured intervention programme aimed at preparing adolescents with developmental language disorders for job interviews. Our primary outcome measures included change in ratings of verbal and non-verbal social communication behaviours evident during mock interviews. METHODS & PROCEDURES: In study 1, 12 participants, aged 17-19 years, from a specialist sixth-form college completed the intervention and two mock interviews, one pre- and one post-intervention...
April 18, 2017: International Journal of Language & Communication Disorders
https://www.readbyqxmd.com/read/28421079/severe-sequelae-to-mold-related-illness-as-demonstrated-in-two-finnish-cohorts
#16
Tamara Tuuminen, Kyösti Sakari Rinne
The presence of toxic indoor molds with accompanying bacterial growth is clearly detrimental to human health. The pathophysiological and toxicological effects of toxins and structural components of molds and bacteria have been clarified in experiments conducted in tissue culture and animals, and there is convincing epidemiologic evidence; nonetheless their implications for human health are either ignored or denied, at least in Finland. In this communication, we describe two cohorts suffering severe sequelae to mold-related illness...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28419170/evaluation-of-the-relative-efficacy-of-a-couple-cognitive-behaviour-therapy-cbt-for-premenstrual-disorders-pmds-in-comparison-to-one-to-one-cbt-and-a-wait-list-control-a-randomized-controlled-trial
#17
Jane M Ussher, Janette Perz
DESIGN: A randomised control trial (RCT) was conducted to examine the efficacy of couple-based cognitive behaviour therapy (CBT) for Premenstrual Disorders (PMDs), in comparison to one-to-one CBT and a wait-list control. METHODS: Triangulation of quantitative and qualitative outcome measures evaluated changes pre-post intervention. Eighty three women were randomly allocated across three conditions, with 63 completing post-intervention measures, a retention rate of 76%...
2017: PloS One
https://www.readbyqxmd.com/read/28417950/differential-gender-effects-in-the-relationship-between-perceived-immune-functioning-and-autistic-traits
#18
Marlou Mackus, Deborah de Kruijff, Leila S Otten, Aletta D Kraneveld, Johan Garssen, Joris C Verster
Altered immune functioning has been demonstrated in individuals with autism spectrum disorder (ASD). The current study explores the relationship between perceived immune functioning and experiencing ASD traits in healthy young adults. N = 410 students from Utrecht University completed a survey on immune functioning and autistic traits. In addition to a 1-item perceived immune functioning rating, the Immune Function Questionnaire (IFQ) was completed to assess perceived immune functioning. The Dutch translation of the Autism-Spectrum Quotient (AQ) was completed to examine variation in autistic traits, including the domains "social insights and behavior", "difficulties with change", "communication", "phantasy and imagination", and "detail orientation"...
April 12, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28417440/developmental-neurotoxicity-of-traffic-related-air-pollution-focus-on-autism
#19
REVIEW
Lucio G Costa, Yu-Chi Chang, Toby B Cole
PURPOSE OF REVIEW: Epidemiological and animal studies suggest that air pollution may negatively affect the central nervous system (CNS) and contribute to CNS diseases. Traffic-related air pollution is a major contributor to global air pollution, and diesel exhaust (DE) is its most important component. RECENT FINDINGS: Several studies suggest that young individuals may be particularly susceptible to air pollution-induced neurotoxicity and that perinatal exposure may cause or contribute to developmental disabilities and behavioral abnormalities...
April 17, 2017: Current Environmental Health Reports
https://www.readbyqxmd.com/read/28413687/what-we-have-changed-our-minds-about-part-1-borderline-personality-disorder-as-a-limitation-of-resilience
#20
REVIEW
Peter Fonagy, Patrick Luyten, Elizabeth Allison, Chloe Campbell
This paper sets out a recent transition in our thinking in relation to psychopathology associated with personality disorder, in an approach that integrates our thinking about attachment, mentalizing (understanding ourselves and others in terms of intentional mental states) and epistemic trust (openness to the reception of social communication that is personally relevant and of generalizable significance) with recent findings on the structure of both adult and child psychopathology and resilience. In this paper - the first of two parts - we review evidence suggesting that a general psychopathology or p factor underlies vulnerability for psychopathology...
2017: Borderline Personality Disorder and Emotion Dysregulation
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