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https://www.readbyqxmd.com/read/28633287/genetic-diseases-and-aneuploidies-can-be-detected-with-a-single-blastocyst-biopsy-a-successful-clinical-approach
#1
Maria Giulia Minasi, Francesco Fiorentino, Alessandra Ruberti, Anil Biricik, Elisabetta Cursio, Ettore Cotroneo, Maria Teresa Varricchio, Matteo Surdo, Francesca Spinella, Ermanno Greco
STUDY QUESTION: Can simultaneous detection of aneuploidies and genetic diseases or chromosomal aberrations in blastocysts reduce the chance of transferring embryos with low implantation potential, guaranteeing good clinical outcomes? SUMMARY ANSWER: The screening for chromosomal aneuploidies revealed that 50.6% of blastocysts diagnosed free of genetic disease or balanced, were aneuploid, therefore avoiding the transfer of blastocysts potentially resulting in implantation failures, miscarriages, or in some cases, in health affected live births...
June 12, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28632916/diastasis-of-the-pubic-symphysis-following-vaginal-delivery
#2
Bhumireddy Sujana, Anish Keepanasseril, Dilip K Maurya
Diastasis of the pubic symphysis following vaginal delivery has been reported to occur during 1 in 300-30 000 deliveries [1, 2]. The present study describes two patients who presented at the Jawaharlal Institute of Postgraduate Medical Education & Research, Pondicherry, India, between July 2014 and December 2015 immediately postpartum after instrumental vaginal delivery. The patients provided written informed consent for the publication of the present study. This article is protected by copyright. All rights reserved...
June 20, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28632532/postpartum-tubal-sterilization-making-the-case-for-urgency
#3
Michael G Richardson, Sarah J Hall, Lisa C Zuckerwise
The parturient who requests postpartum sterilization has given consideration to and has made decisions regarding this aspect of her medical care long before her delivery. She arrives at parturition expecting the postpartum procedure to be performed as intended. The American Congress of Obstetricians and Gynecologists has reaffirmed its opinion that postpartum sterilization is an urgent procedure, owing to the safety and superior effectiveness of tubal sterilization via minilaparotomy in the immediate postpartum period, and the adverse consequences for mothers, babies, and society when the procedure is not actualized as desired and intended...
June 17, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28631962/needlestick-injuries-in-interventional-radiology-are-common-and-underreported
#4
Amy R Deipolyi, Anand M Prabhakar, Sailendra Naidu, Rahmi Oklu
Purpose To determine the prevalence of and risk factors for needlesticks in interventional radiology physicians, as well as the attitudes, behaviors, and conditions that promote or interfere with reporting of these injuries. Materials and Methods A total of 3889 interventional radiologists from academic and private practice in the United States were surveyed by emailing all interventional radiologist members of the Society of Interventional Radiology, including attending-level physicians and trainees (April-August 2016)...
June 19, 2017: Radiology
https://www.readbyqxmd.com/read/28631150/low-dose-subcutaneous-ketamine-for-postoperative-pain-management-in-rwanda-a-dose-finding-study
#5
Jon Tuchscherer, William P McKay, Theogene Twagirumugabe
PURPOSE: Good pain control is not a normal part of surgical care in sub-Saharan Africa due to lack of resources. The primary objective of this study was to determine an efficacious dose of subcutaneous ketamine for postoperative pain for use in a future randomized controlled trial. METHODS: Following research ethics board and local hospital approval for this research, we obtained informed consent from 31 patients undergoing major surgery for a random walk dose-finding study...
June 19, 2017: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/28629849/analysis-of-archived-newborn-dried-blood-spots-dbs-identifies-congenital-cytomegalovirus-as-a-major-cause-of-unexplained-pediatric-sensorineural-hearing-loss
#6
Lucy Meyer, Bazak Sharon, Tina C Huang, Abby C Meyer, Kristin E Gravel, Lisa A Schimmenti, Elizabeth C Swanson, Hannah E Herd, Nelmary Hernandez-Alvarado, Kirsten R Coverstone, Mark McCann, Mark R Schleiss
PURPOSE: Congenital cytomegalovirus (cCMV) infection is the most common non-genetic cause of sensorineural hearing loss (SNHL). However, accurate diagnosis of cCMV as the etiology of SNHL is problematic beyond the neonatal period. This study therefore examined whether cCMV infection could be identified retrospectively in children presenting with unexplained SNHL to a multidisciplinary diagnostic outpatient otolaryngology clinic at an academic medical center in Minnesota. METHODS: Over a 4-year period, 57 patients with an age range of 3months to 10years with unexplained SNHL were recruited to participate in this study...
June 7, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28629605/ct-findings-in-11-patients-with-tafro-syndrome-a-variant-of-multicentric-castleman-s-disease
#7
T Kiguchi, C Sato, K Takai, Y Nakai, Y Kaneko, M Matsuki
AIM: To assess detailed computed tomography (CT) findings in patients with the recently described thrombocytopenia, anasarca, fever, reticulin fibrosis, and organomegaly (TAFRO) syndrome, in order to contribute to imaging interpretation in the challenging diagnosis of this disease. MATERIALS AND METHODS: The institutional review board approved this retrospective study and waived the need for informed consent. Eleven patients (six men, five women; mean age, 52.5 years) with confirmed TAFRO syndrome were included in this study...
June 16, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28629573/added-value-of-prone-ct-in-the-assessment-of-honeycombing-and-classification-of-usual-interstitial-pneumonia-pattern
#8
Minjae Kim, Sang Min Lee, Jae-Woo Song, Kyung-Hyun Do, Hyun Joo Lee, Soyeoun Lim, Jooae Choe, Kye Jin Park, Hyo Jung Park, Hwa Jung Kim, Joon Beom Seo
OBJECTIVE: To retrospectively investigate whether prone CT improves identification of honeycombing and classification of UIP patterns in terms of interobserver agreement and accuracy using pathological results as a reference standard. MATERIALS AND METHODS: Institutional review board approval with waiver of patients' informed consent requirement was obtained. HRCTs of 86 patients with pathologically proven UIP, NSIP and chronic HP between January 2011 and April 2015 were evaluated by 8 observers...
June 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28629572/3t-diffusion-weighted-mri-in-the-response-assessment-of-colorectal-liver-metastases-after-chemotherapy-correlation-between-adc-value-and-histological-tumour-regression-grading
#9
Francescamaria Donati, Piero Boraschi, Federica Pacciardi, Rosa Cervelli, Maura Castagna, Lucio Urbani, Fabio Falaschi, Davide Caramella
PURPOSE: The purpose of the study was to correlate the apparent diffusion coefficient (ADC) values of diffusion-weighted MR imaging (DW-MRI) by 3T device with the histological tumour regression grading (TRG) analysis of colorectal liver metastases after preoperative chemotherapy. MATERIALS AND METHODS: Our study included thirty-five patients with colorectal liver metastases who had undergone MRI by 3T device (GE DISCOVERY MR750; GE Healthcare) after preoperative chemotherapy...
June 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28628656/ultrasound-guided-cable-free-13-gauge-vacuum-assisted-biopsy-of-non-mass-breast-lesions
#10
Jiwoon Seo, Sun Mi Kim, Mijung Jang, Bo La Yun, Soo Hyun Lee, Eun-Kyu Kim, Eunyoung Kang, So Yeon Park, Woo Kyung Moon, Hye Young Choi, Bohyoung Kim
PURPOSE: To compare the outcomes of ultrasound-guided core biopsy for non-mass breast lesions by the novel 13-gauge cable-free vacuum-assisted biopsy (VAB) and by the conventional 14-gauge semi-automated core needle biopsy (CCNB). MATERIALS AND METHODS: Our institutional review board approved this prospective study, and all patients provided written informed consent. Among 1840 ultrasound-guided percutaneous biopsies performed from August 2013 to December 2014, 145 non-mass breast lesions with suspicious microcalcifications on mammography or corresponding magnetic resonance imaging finding were subjected to 13-gauge VAB or 14-gauge CCNB...
2017: PloS One
https://www.readbyqxmd.com/read/28626811/the-enrich-study-to-evaluate-the-effectiveness-of-a-combination-intervention-package-to-improve-isoniazid-preventive-therapy-initiation-adherence-and-completion-among-people-living-with-hiv-in-ethiopia-rationale-and-design-of-a-mixed-methods-cluster-randomized
#11
Andrea A Howard, Yael Hirsch-Moverman, Suzue Saito, Tsigereda Gadisa, Amrita Daftary, Zenebe Melaku
BACKGROUND: Isoniazid preventive therapy (IPT) prevents tuberculosis among HIV-positive individuals, however implementation is suboptimal. Implementation science studies are needed to identify interventions to address this evidence-to-program gap. OBJECTIVE: The ENRICH Study is a mixed methods cluster randomized trial aimed at evaluating the effectiveness and acceptability of a combination intervention package (CIP) to improve IPT implementation in Ethiopia. DESIGN: Ten health centers were randomized to receive the CIP or standard of care...
June 2017: Contemporary Clinical Trials Communications
https://www.readbyqxmd.com/read/28625581/point-should-informed-consent-be-required-for-apnea-testing-in-patients-with-suspected-brain-death-no
#12
EDITORIAL
Ariane Lewis, David Greer
No abstract text is available yet for this article.
June 12, 2017: Chest
https://www.readbyqxmd.com/read/28625580/counterpoint-should-informed-consent-be-required-for-apnea-testing-in-patients-with-suspected-brain-death-yes
#13
EDITORIAL
Robert D Truog, Robert C Tasker
No abstract text is available yet for this article.
June 12, 2017: Chest
https://www.readbyqxmd.com/read/28624906/pathogen-reduction-inactivation-of-products-for-the-treatment-of-bleeding-disorders-what-are-the-processes-and-what-should-we-say-to-patients
#14
Giovanni Di Minno, David Navarro, Carlo Federico Perno, Mariana Canaro, Lutz Gürtler, James W Ironside, Hermann Eichler, Andreas Tiede
Patients with blood disorders (including leukaemia, platelet function disorders and coagulation factor deficiencies) or acute bleeding receive blood-derived products, such as red blood cells, platelet concentrates and plasma-derived products. Although the risk of pathogen contamination of blood products has fallen considerably over the past three decades, contamination is still a topic of concern. In order to counsel patients and obtain informed consent before transfusion, physicians are required to keep up to date with current knowledge on residual risk of pathogen transmission and methods of pathogen removal/inactivation...
June 18, 2017: Annals of Hematology
https://www.readbyqxmd.com/read/28624023/enhanced-radiation-damage-caused-by-iodinated-contrast-agents-during-ct-examination
#15
Ling Wang, Qiang Li, Xi-Ming Wang, Guang-Yu Hao, Jie-Bao, Su Hu, Chun-Hong Hu
OBJECTIVE: To access the effect of iodinate contrast agent (ICA) on DNA double-stand breaks (DSBs) in human peripheral blood lymphocytes during computed tomography (CT) examinations. MATERIALS AND METHODS: This present study was approved by the institutional ethics committee; written informed patient consent was obtained from 70 patients. A total of 48 patients underwent computed tomography urography (CTU), in which only one time CT scanning was examined after injecting ICA, and 22 patients received unenhanced whole abdominal CT, among them 10 patients were selected to get ICA injection immediately after irradiation...
July 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28624018/difference-in-the-craniocaudal-gradient-of-the-maximum-pixel-value-change-rate-between-chronic-obstructive-pulmonary-disease-patients-and-normal-subjects-using-sub-mgy-dynamic-chest-radiography-with-a-flat-panel-detector-system
#16
Yoshitake Yamada, Masako Ueyama, Takehiko Abe, Tetsuro Araki, Takayuki Abe, Mizuki Nishino, Masahiro Jinzaki, Hiroto Hatabu, Shoji Kudoh
OBJECTIVES: To compare the craniocaudal gradients of the maximum pixel value change rate (MPCR) during tidal breathing between chronic obstructive pulmonary disease (COPD) patients and normal subjects using dynamic chest radiography. MATERIALS AND METHODS: This prospective study was approved by the institutional review board and all participants provided written informed consent. Forty-three COPD patients (mean age, 71.6±8.7 years) and 47 normal subjects (non-smoker healthy volunteers) (mean age, 54...
July 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28623998/ruptured-common-femoral-vein-pseudoaneurysm-from-a-common-femoral-arteriovenous-fistula-presenting-as-lower-extremity-steal-after-radiofrequency-ablation-of-the-great-saphenous-vein
#17
Robert Scott Brumberg, Cassie Davis
Radiofrequency ablation of the superficial venous systems has become one of the mainstays of minimally invasive approaches to varicose veins and chronic venous insufficiency. These procedures have high rates of success with scarce complications. This case report highlights a patient with a common femoral arteriovenous fistula presenting with lower extremity steal after radiofrequency ablation treatment of the great saphenous vein. During operative repair of the arteriovenous fistula, a pseudoaneurysm of the common femoral vein ruptured...
July 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/28623892/improving-transitions-in-acute-stroke-patients-discharged-to-home-the-michigan-stroke-transitions-trial-mistt-protocol
#18
Mathew J Reeves, Anne K Hughes, Amanda T Woodward, Paul P Freddolino, Constantinos K Coursaris, Sarah J Swierenga, Lee H Schwamm, Michele C Fritz
BACKGROUND: For some stroke patients and caregivers, navigating the transition between hospital discharge and returning home is associated with substantial psychosocial and health-related challenges. Currently, no evidence-based standard of care exists that addresses the concerns of stroke patients and caregivers during the transition period. Objectives of the Michigan Stroke Transitions Trial (MISTT) are to test the impact of a social worker home-based case management program, as well as an online information and support resource, on patient and caregiver outcomes after returning home...
June 17, 2017: BMC Neurology
https://www.readbyqxmd.com/read/28622448/ileocecal-valve-syndrome-after-surgery-in-adult-patients-myth-or-reality
#19
S Palmisano, M Silvestri, M Troian, P Germani, F Giudici, N de Manzini
AIM: The onset of symptoms after ileocecal valve (ICV) removal may be perceived as an unwanted effect of surgery and induce patients to bring unnecessary litigation against surgeons. The aim of our study is to assess the real impact on the quality of life of patients whose ICV was surgically removed, using three validated questionnaires. METHOD: In patients who had their ICV removed surgically, the Gastrointestinal Quality of life (GIQLI) questionnaire and those used by the European Organization for research and Treatment of Cancer (EORTC) were administered pre and post surgery...
June 16, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/28621833/multiple-external-cervical-root-resorptions-after-home-bleaching-treatment-with-22-carbamide-peroxide
#20
Glauco Rodrigues Velloso, Marcos Motta de Freitas, Adriana Terezinha Neves Novellino Alves, Alan Roger Santos Silva, Eliane Dos Santos Porto Barboza, Vittorio Moraschini
Invasive multiple cervical root resorptions after vital tooth bleaching is a rare condition. The aim of this article is to present a case of multiple external cervical root resorptions (ECRR) after a misguided home whitening treatment. A 34-year-old male patient presented with slight sensitivity and mobility in several teeth. Despite the manufacturer's recommendations, the patient used a 22% carbamide peroxide-based tooth bleaching gel at home for 4 consecutive days, at night, on the upper and lower arches...
June 16, 2017: Australian Dental Journal
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