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https://www.readbyqxmd.com/read/28944220/determinants-for-further-wishes-for-cosmetic-and-reconstructive-interventions-in-1652-patients-with-surgical-treated-carcinomas-of-the-oral-cavity
#1
Henrik Holtmann, Simon Spalthoff, Nils-Claudius Gellrich, Jörg Handschel, Julian Lommen, Norbert R Kübler, Gertrud Krüskemper, Majeed Rana, Karoline Sander
BACKGROUND: The impairment of the appearance is a major problem for patients with carcinomas of the oral cavity. These patients want to recover their preoperative facial appearance. Some do not realize that this is not always possible and hence develop a desire for further cosmetic and reconstructive surgery (CRS) which often causes psychological problems. METHOD: The desire of patients for CRS (N = 410; 26%) has been acquired in this DÖSAK rehab study including multiple reasons such as medical, functional, aesthetic and psychosocial aspects...
December 2017: Maxillofacial Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28943593/nationwide-survey-on-informed-consent-and-ethical-review-at-hospitals-conducting-post-marketing-studies-sponsored-by-pharmaceutical-companies
#2
Hisashi Urushihara, Yuka Murakami, Kenji Matsui, Shimon Tashiro
<bibitem lang="en">  Under the Japanese drug regulatory system, post-marketing studies (PMS) must be in compliance with Good Post-marketing Study Practice (GPSP). The GPSP Ordinance lacks standards for the ethical conduct of PMSs; although only post-marketing clinical trials are subject to Good Clinical Practice. <bibitem lang="en">  We conducted a web-based questionnaire survey on the ethical conduct of PMSs in collaboration with the Japanese Society of Hospital Pharmacists and pharmacists belonging to the Society...
September 25, 2017: Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan
https://www.readbyqxmd.com/read/28943259/-spanish-collaborative-study-description-of-usual-clinical-practice-in-infant-obesity
#3
Alfonso Lechuga Sancho, Enrique Palomo Atance, María José Rivero Martin, Mercedes Gil-Campos, Rosaura Leis Trabazo, María Pilar Bahíllo Curieses, Gloria Bueno Lozano
INTRODUCTION: Childhood obesity is a high prevalence health problem. Although there are clinical guidelines for its management, there is variability in its clinical approach. The aim of this study is to describe the usual clinical practice in Paediatric Endocrinology Units in Spain and to evaluate if it resembles the recommended guidelines. MATERIAL AND METHODS: An observational, cross-sectional and descriptive study was carried out by means of a questionnaire sent to paediatric endocrinologists of the Spanish Society of Paediatric Endocrinology...
September 21, 2017: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/28940368/cerebral-oximetry-and-postoperative-delirium-after-cardiac-surgery-a-randomised-controlled-trial
#4
L Lei, R Katznelson, L Fedorko, J Carroll, H Poonawala, M Machina, R Styra, V Rao, G Djaiani
Postoperative delirium is associated with increased morbidity and mortality. We hypothesised that restoration of regional cerebral oxygen desaturation would reduce the incidence of postoperative delirium in elderly patients after cardiac surgery. After institutional ethics review board approval and informed consent, a double-blinded, prospective, randomised, controlled trial was conducted in patients ≥ 60 years of age undergoing cardiac surgery with cardiopulmonary bypass. In the intervention group, an algorithm was commenced if regional cerebral oxygen saturation decreased below 75% of baseline value for 1 min or longer...
September 22, 2017: Anaesthesia
https://www.readbyqxmd.com/read/28938979/a-survey-of-patients-preoperative-need-for-information-about-postoperative-pain-effect-of-previous-surgery-experience
#5
Paraskevi Mavridou, Adamantia Manataki, Elena Arnaoutoglou, Dimitrios Damigos
PURPOSE: The aim of this study was to determine the kind of information patients need preoperatively about postoperative pain (POP) and whether this is affected by previous surgery experience. DESIGN: A descriptive study design using preoperative questionnaires. METHODS: Questionnaires with fixed questions related to POP and its management were distributed preoperatively to consenting, consecutive surgical patients. Patients were divided into two groups: patients with previous surgery experience (group A) and patients without previous surgery experience (group B)...
October 2017: Journal of Perianesthesia Nursing: Official Journal of the American Society of PeriAnesthesia Nurses
https://www.readbyqxmd.com/read/28938900/the-role-and-benefits-of-accessing-primary-care-patient-records-during-unscheduled-care-a-systematic-review
#6
Tom Bowden, Enrico Coiera
BACKGROUND: The purpose of this study was to assess the impact of accessing primary care records on unscheduled care. Unscheduled care is typically delivered in hospital Emergency Departments. Studies published to December 2014 reporting on primary care record access during unscheduled care were retrieved. RESULTS: Twenty-two articles met inclusion criteria from a pool of 192. Many shared electronic health records (SEHRs) were large in scale, servicing many millions of patients...
September 22, 2017: BMC Medical Informatics and Decision Making
https://www.readbyqxmd.com/read/28938309/successful-treatment-with-dabigatran-for-consumptive-coagulopathy-associated-with-extensive-vascular-malformations
#7
Atsushi Yasumoto, Ryohei Ishiura, Mitsunaga Narushima, Yutaka Yatomi
: Vascular malformation is occasionally complicated by consumptive coagulopathy, known as localized intravascular coagulopathy (LIC), which is characterized by a reduced fibrinogen level, an elevated D-dimer level and a normal platelet count. We report the case of a 17-year-old Japanese girl who presented with LIC secondary to extensive vascular malformations, whose condition had progressed to disseminated intravascular coagulation (DIC). She suddenly presented with severe anaemia, despite the absence of obvious bleeding, and she began to require regular red blood cell (RBC) transfusions...
September 21, 2017: Blood Coagulation & Fibrinolysis: An International Journal in Haemostasis and Thrombosis
https://www.readbyqxmd.com/read/28938284/longitudinal-validation-of-the-promis-physical-function-item-bank-in-upper-extremity-trauma
#8
Aaron J Kaat, Nan E Rothrock, Mark S Vrahas, Robert V OʼToole, Sarah K Buono, Timothy Zerhusen, Richard C Gershon
OBJECTIVES: To evaluate the reliability, validity, and responsiveness of the Patient-Reported Outcomes Measurement Information System (PROMIS) Upper Extremity Computer Adaptive Test (UE-CAT) and the 8-item Physical Function short form (PF-SF8a) for monitoring outcomes after musculoskeletal injuries in upper extremity trauma patients. DESIGN: Prospective cohort study. SETTING: Two Level-I trauma centers. PATIENTS: Eligible consecutive patients were approached and 424 consented at time 1 (median 9...
October 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28937898/selective-reduction-of-talon-cusps-a-case-series
#9
Rona Leith, Anne C O'Connell
Talon cusps associated with permanent incisors are a rare occurrence but can cause numerous complications. When treatment is indicated options include radical or selective reduction of the accessory cusp, but there is no standard protocol for management. STUDY DESIGN: Patients referred to the Dublin Dental University Hospital for treatment of talon cusps were identified, contacted and consent obtained. Clinical notes, photographs and radiographs were retrospectively reviewed. RESULTS: Eleven patients with 14 talon cusps were identified...
September 22, 2017: Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/28937853/assessment-of-microvascular-invasion-of-hepatocellular-carcinoma-with-diffusion-kurtosis-imaging
#10
Wen-Tao Wang, Li Yang, Zhao-Xia Yang, Xin-Xing Hu, Ying Ding, Xu Yan, Cai-Xia Fu, Robert Grimm, Meng-Su Zeng, Sheng-Xiang Rao
Purpose To evaluate the potential role of diffusion kurtosis imaging and conventional magnetic resonance (MR) imaging findings including standard monoexponential model of diffusion-weighted imaging and morphologic features for preoperative prediction of microvascular invasion (MVI) of hepatocellular carcinoma (HCC). Materials and Methods Institutional review board approval and written informed consent were obtained. Between September 2015 and November 2016, 84 patients (median age, 54 years; range, 29-79 years) with 92 histopathologically confirmed HCCs (40 MVI-positive lesions and 52 MVI-negative lesions) were analyzed...
September 22, 2017: Radiology
https://www.readbyqxmd.com/read/28936819/-the-scope-quality-and-safety-requirements-of-drug-abuse-testing
#11
Tuncay Küme, Çiğdem Karakükcü, Aslı Pınar, Hakan Coşkunol
The aim of this review is to inform about the scopes and requirements of drug abuse testing. Drug abuse testing is one of the tools for determination of drug use. It must fulfill the quality and safety requirements in judgmental legal and administrative decisions. Drug abuse testing must fulfill some requirements like selection of the appropriate test matrix, appropriate screening test panel, sampling in detection window, patient consent, identification of the donor, appropriate collection site, sample collection with observation, identification and control of the sample, specimen custody chain in preanalytical phase; analysis in authorized laboratories, specimen validity tests, reliable testing METHODS, strict quality control, two-step analysis in analytical phase; storage of the split specimen, confirmation of the split specimen in the objection, result custody chain, appropriate cut-off concentration, the appropriate interpretation of the result in postanalytical phase...
2017: Türk Psikiyatri Dergisi, Turkish Journal of Psychiatry
https://www.readbyqxmd.com/read/28936064/knowledge-and-attitude-of-nursing-students-toward-electroconvulsive-therapy
#12
Nitasha Sharma, Sandhya Ghai, Sandeep Grover
BACKGROUND: Electroconvulsive therapy (ECT) is one of the commonly used treatment modalities for patients with severe mental disorders. However, acceptance of ECT by the patient and relatives often depends on how the health-care professionals themselves present the treatment modality to the patients and their relatives. There is a lack of information about the knowledge and attitude toward ECT among health professionals. AIM: This study aimed to evaluate the knowledge about and attitude toward ECT among nursing students...
August 2017: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/28933329/-mid-term-to-long-term-results-of-revision-total-hip-arthroplasty-using-the-oval-shaped-acetabular-cup-tc-type
#13
E Šťastný, T Trč, J Frýdl, Z Kopečný, T Philippou, J Lisý
INTRODUCTION The purpose of our paper is to evaluate the mid-term to long-term results and to confirm the basic criteria of a high-quality revision implant: safe bridging of bone defects, achievement of reliable primary fixation of revision acetabular cup, achievement of good secondary stability with documentable osteointegration of cup and demonstration of remodelling of transplanted bone tissue in the area of defects and in spaces between the implant ribs. MATERIAL AND METHODS Altogether 36 patients (38 cups) were evaluated who had undergone revision hip arthroplasty in the period from 2004 to 2010...
2017: Acta Chirurgiae Orthopaedicae et Traumatologiae Cechoslovaca
https://www.readbyqxmd.com/read/28933226/nursing-adherence-to-ethical-codes-in-pediatric-oncology-wards
#14
Raziyeh Beykmirza, Lida Nikfarid, Foroozan Atashzadeh-Shoorideh, Maliheh Nasiri
BACKGROUND: The nature of children's cancer comes with lots of ethical issues. Nurses are encouraged to adhere to ethical codes in their practice. OBJECTIVES: This study aimed to compare the perspectives of nurses and mothers of children with cancer regarding the adherence of nurses to ethical codes. RESEARCH DESIGN: In this descriptive-comparative study, a researcher-made questionnaire was used to assess the amount of adherence to Iranian nurses' code of ethics in perspectives of pediatric oncology nurses and mothers...
January 1, 2017: Nursing Ethics
https://www.readbyqxmd.com/read/28932963/echocardiographic-screening-of-rheumatic-heart-disease-in-american-samoa
#15
Jennifer H Huang, Michael Favazza, Arthur Legg, Kathryn W Holmes, Laurie Armsby, Ipuniuesea Eliapo-Unutoa, Thomas Pilgrim, Erin J Madriago
While rheumatic heart disease (RHD) is a treatable disease nearly eradicated in the United States, it remains the most common form of acquired heart disease in the developing world. This study used echocardiographic screening to determine the prevalence of RHD in children in American Samoa. Screening took place at a subset of local schools. Private schools were recruited and public schools underwent cluster randomization based on population density. We collected survey information and performed a limited physical examination and echocardiogram using the World Heart Federation protocol for consented school children aged 5-18 years old...
September 20, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/28932961/enrolling-genomics-research-participants-through-a-clinical-setting-the-impact-of-existing-clinical-relationships-on-informed-consent-and-expectations-for-return-of-research-results
#16
Courtney Berrios, Cynthia A James, Karen Raraigh, Juli Bollinger, Brittney Murray, Crystal Tichnell, Carolyn D Applegate, Amanda L Bergner
Genetic counselors working in a clinical setting may find themselves recruiting, enrolling, and returning results for genomic research, and existing clinical relationships with study participants may impact these research interactions. We present a qualitative study using semi-structured interviews of participants enrolled in a genome sequencing/exome sequencing (GS/ES) study at the same institution where they receive clinical care. Interviews were coded for motivations to participate and expectations of this research...
September 20, 2017: Journal of Genetic Counseling
https://www.readbyqxmd.com/read/28932767/patient-specific-workup-of-adrenal-incidentalomas
#17
REVIEW
Romy R de Haan, Johannes B R Visser, Ewoud Pons, Richard A Feelders, Uzay Kaymak, M G Myriam Hunink, Jacob J Visser
PURPOSE: : To develop a clinical prediction model to predict a clinically relevant adrenal disorder for patients with adrenal incidentaloma. MATERIALS AND METHODS: : This retrospective study is approved by the institutional review board, with waiver of informed consent. Natural language processing is used for filtering of adrenal incidentaloma cases in all thoracic and abdominal CT reports from 2010 till 2012. A total of 635 patients are identified. Stepwise logistic regression is used to construct the prediction model...
2017: European Journal of Radiology Open
https://www.readbyqxmd.com/read/28931411/topiramate-s-effectiveness-on-weight-reduction-in-overweight-obese-persons-with-schizophrenia-study-protocol-for-a-randomized-controlled-trial
#18
Miyuru Chandradasa, Layani Champika, Silumini de Silva, K A L A Kuruppuarachchi
BACKGROUND: Schizophrenia is a psychiatric disorder with a higher mortality than that of the general population. Most of the deaths are due to cardiovascular causes and are related to metabolic risks. This risk is due not only to antipsychotics but also to inherent factors of the disorder. Studies in the West have shown topiramate to be effective in schizophrenia to reduce weight gain and for symptomatic control. Whether this is effective for South Asians is not known. It is important because South Asians have a higher risk of metabolic syndrome...
September 20, 2017: Trials
https://www.readbyqxmd.com/read/28931031/reducing-therapeutic-misconception-a-randomized-intervention-trial-in-hypothetical-clinical-trials
#19
Paul P Christopher, Paul S Appelbaum, Debbie Truong, Karen Albert, Louise Maranda, Charles Lidz
BACKGROUND: Participants in clinical trials frequently fail to appreciate key differences between research and clinical care. This phenomenon, known as therapeutic misconception, undermines informed consent to clinical research, but to date there have been no effective interventions to reduce it and concerns have been expressed that to do so might impede recruitment. We determined whether a scientific reframing intervention reduces therapeutic misconception without significantly reducing willingness to participate in hypothetical clinical trials...
2017: PloS One
https://www.readbyqxmd.com/read/28929695/-effects-of-mongolia-astragali-radix-in-protecting-early-cardiac-and-nephritic-functions-of-patients-of-hypertension-with-metabolic-syndrome
#20
Ning-Yin Li, Xiu-Li Li, Xiao-Ping Zhai, Qiong-Ying Wang, Xiao-Wei Zhang, Feng Zhao, Xiao-Feng Wang, Jian-Yun Fan, Feng Bai, Jing Yu
To explore the effect of Mongolia Astragali Radix produced in Longxi of Gansu province in protecting cardiac and nephritic functions of patients of essential hypertension(EH) with metabolic syndrome(MetS). A total of two hundred and twenty-six EH patients with MetS aged above 18 were selected. Patients were randomly divided to control group(adopted conventional medical treatment), Astragali Radix group 1(added Astragali Radix capsules 10 g•d⁻¹ besides conventional medical treatment) and Astragali Radix group 2(added Astragali Radix capsules 5 g•d⁻¹ besides conventional medical treatment)...
November 2016: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
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